TreeWAS – Variant ID: rs8083786

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	0.970	0.030	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.966	0.034	0.000
E03 Other hypothyroidism	0.966	0.034	0.000
E20-E35 Disorders of other endocrine glands	0.966	0.034	0.000
E10-E14 Diabetes mellitus	0.964	0.036	0.000
E10 Insulin-dependent diabetes mellitus	0.962	0.038	0.000
E00-E07 Disorders of thyroid gland	0.962	0.038	0.000
E10.3 With ophthalmic complications	0.935	0.065	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.920	0.080	0.000
E10.9 Without complications	0.919	0.081	0.000
E21.0 Primary hyperparathyroidism	0.874	0.126	0.000
K51.9 Ulcerative colitis, unspecified	0.867	0.133	0.000
K50-K52 Noninfective enteritis and colitis	0.862	0.138	0.000
K51 Ulcerative colitis	0.861	0.139	0.000
K90.0 Coeliac disease	0.861	0.139	0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.858	0.142	0.000
K11 Diseases of salivary glands	0.856	0.144	0.000
K90 Intestinal malabsorption	0.854	0.146	0.000
E27 Other disorders of adrenal gland	0.853	0.147	0.000
K50 Crohn's disease [regional enteritis]	0.842	0.158	0.000
K90-K93 Other diseases of the digestive system	0.840	0.160	0.000
Chapter XI Diseases of the digestive system	0.839	0.161	0.000
K07 Dentofacial anomalies [including malocclusion]	0.833	0.167	0.000
E24 Cushing's syndrome	0.831	0.169	0.000
E29 Testicular dysfunction	0.830	0.170	0.000
E13 Other specified diabetes mellitus	0.818	0.182	0.000
E03.1 Congenital hypothyroidism without goitre	0.805	0.195	0.000
E27.8 Other specified disorders of adrenal gland	0.800	0.200	0.000
E10.1 With ketoacidosis	0.797	0.203	0.000
E22 Hyperfunction of pituitary gland	0.789	0.211	0.000
E23 Hypofunction and other disorders of pituitary gland	0.786	0.214	0.000
K50.8 Other Crohn's disease	0.785	0.215	0.000
K11.1 Hypertrophy of salivary gland	0.778	0.222	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.772	0.228	0.000
E10.6 With other specified complications	0.769	0.231	0.000
K11.5 Sialolithiasis	0.764	0.236	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.760	0.240	0.000
K05 Gingivitis and periodontal diseases	0.760	0.240	0.000
E34 Other endocrine disorders	0.760	0.240	0.000
K90.9 Intestinal malabsorption, unspecified	0.758	0.242	0.000
E14 Unspecified diabetes mellitus	0.753	0.247	0.000
K00 Disorders of tooth development and eruption	0.752	0.248	0.000
K13 Other diseases of lip and oral mucosa	0.750	0.250	0.000
E28 Ovarian dysfunction	0.745	0.255	0.000
K11.3 Abscess of salivary gland	0.743	0.257	0.000
K50.0 Crohn's disease of small intestine	0.741	0.259	0.000
E26 Hyperaldosteronism	0.739	0.261	0.000
K51.4 Pseudopolyposis of colon	0.738	0.262	0.000
K11.9 Disease of salivary gland, unspecified	0.738	0.262	0.000
K11.2 Sialoadenitis	0.736	0.264	0.000
K07.6 Temporomandibular joint disorders	0.736	0.264	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.735	0.265	0.000
E29.1 Testicular hypofunction	0.732	0.268	0.000
K12 Stomatitis and related lesions	0.727	0.273	0.000
K07.3 Anomalies of tooth position	0.722	0.277	0.000
K07.9 Dentofacial anomaly, unspecified	0.718	0.282	0.000
E13.9 Without complications	0.713	0.287	0.000
E10.4 With neurological complications	0.711	0.289	0.000
E07 Other disorders of thyroid	0.710	0.290	0.000
K13.7 Other and unspecified lesions of oral mucosa	0.707	0.293	0.000
E10.2 With renal complications	0.703	0.296	0.000
E24.9 Cushing's syndrome, unspecified	0.703	0.297	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.702	0.298	0.000
K50.9 Crohn's disease, unspecified	0.702	0.298	0.000
E10.5 With peripheral circulatory complications	0.694	0.306	0.000
E03.5 Myxoedema coma	0.692	0.307	0.000
E03.4 Atrophy of thyroid (acquired)	0.692	0.307	0.000
E03.3 Postinfectious hypothyroidism	0.692	0.307	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.692	0.307	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.692	0.308	0.000
E32 Diseases of thymus	0.692	0.308	0.000
E31 Polyglandular dysfunction	0.692	0.308	0.000
E30 Disorders of puberty, not elsewhere classified	0.692	0.308	0.000
E25 Adrenogenital disorders	0.692	0.308	0.000
E10.0 With coma	0.692	0.308	0.000
E12 Malnutrition-related diabetes mellitus	0.691	0.309	0.000
E10.7 With multiple complications	0.690	0.310	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.690	0.310	0.000
E00 Congenital iodine-deficiency syndrome	0.690	0.310	0.000
K07.1 Anomalies of jaw-cranial base relationship	0.689	0.311	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.689	0.311	0.000
K11.6 Mucocele of salivary gland	0.687	0.313	0.000
E50-E64 Other nutritional deficiencies	0.684	0.316	0.000
E40-E46 Malnutrition	0.684	0.316	0.000
K52 Other non-infective gastro-enteritis and colitis	0.681	0.319	0.000
K04 Diseases of pulp and periapical tissues	0.673	0.327	0.000
K05.1 Chronic gingivitis	0.669	0.331	0.000
E14.9 Without complications	0.664	0.336	0.000
E27.9 Disorder of adrenal gland, unspecified	0.663	0.337	0.000
E10.8 With unspecified complications	0.662	0.338	0.000
E21.3 Hyperparathyroidism, unspecified	0.660	0.340	0.000
E21.4 Other specified disorders of parathyroid gland	0.659	0.340	0.000
E21.2 Other hyperparathyroidism	0.659	0.340	0.000
K51.8 Other ulcerative colitis	0.658	0.342	0.000
K51.1 Ulcerative (chronic) ileocolitis	0.658	0.342	0.000
K12.0 Recurrent oral aphthae	0.656	0.344	0.000
E22.1 Hyperprolactinaemia	0.650	0.349	0.000
K00.0 Anodontia	0.650	0.350	0.000
E14.1 With ketoacidosis	0.646	0.354	0.000
K06 Other disorders of gingiva and edentulous alveolar ridge	0.645	0.355	0.000
K11.8 Other diseases of salivary glands	0.645	0.355	0.000
K07.0 Major anomalies of jaw size	0.638	0.362	0.000
E24.0 Pituitary-dependent Cushing's disease	0.635	0.365	0.000
K03 Other diseases of hard tissues of teeth	0.634	0.366	0.000
E23.7 Disorder of pituitary gland, unspecified	0.634	0.366	0.000
K04.8 Radicular cyst	0.631	0.369	0.000
K05.6 Periodontal disease, unspecified	0.630	0.370	0.000
D50 Iron deficiency anaemia	0.629	0.371	0.000
K90.8 Other intestinal malabsorption	0.627	0.373	0.000
E20 Hypoparathyroidism	0.624	0.376	0.000
K05.4 Periodontosis	0.623	0.377	0.000
D50.9 Iron deficiency anaemia, unspecified	0.622	0.378	0.000
E28.2 Polycystic ovarian syndrome	0.621	0.379	0.000
D50-D53 Nutritional anaemias	0.620	0.380	0.000
D51 Vitamin B12 deficiency anaemia	0.620	0.380	0.000
E24.2 Drug-induced Cushing's syndrome	0.618	0.382	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.617	0.383	0.000
K11.4 Fistula of salivary gland	0.614	0.386	0.000
K11.0 Atrophy of salivary gland	0.614	0.386	0.000
E16 Other disorders of pancreatic internal secretion	0.613	0.387	0.000
K90.3 Pancreatic steatorrhoea	0.612	0.388	0.000
K90.2 Blind loop syndrome, not elsewhere classified	0.612	0.388	0.000
K90.1 Tropical sprue	0.612	0.388	0.000
E27.5 Adrenomedullary hyperfunction	0.612	0.388	0.000
E27.0 Other adrenocortical overactivity	0.612	0.388	0.000
K10 Other diseases of jaws	0.611	0.389	0.000
K00.1 Supernumerary teeth	0.609	0.391	0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.607	0.393	0.000
E23.6 Other disorders of pituitary gland	0.605	0.395	0.000
K50.1 Crohn's disease of large intestine	0.602	0.398	0.000
K93 Disorders of other digestive organs in diseases classified elsewhere	0.602	0.398	0.000
E22.0 Acromegaly and pituitary gigantism	0.602	0.398	0.000
K07.8 Other dentofacial anomalies	0.597	0.403	0.000
K07.5 Dentofacial functional abnormalities	0.597	0.403	0.000
E24.8 Other Cushing's syndrome	0.596	0.404	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.596	0.404	0.000
E24.3 Ectopic ACTH syndrome	0.596	0.404	0.000
E24.1 Nelson's syndrome	0.596	0.404	0.000
K13.4 Granuloma and granuloma-like lesions of oral mucosa	0.596	0.404	0.000
E29.9 Testicular dysfunction, unspecified	0.595	0.405	0.000
E29.8 Other testicular dysfunction	0.595	0.405	0.000
E29.0 Testicular hyperfunction	0.595	0.405	0.000
E34.0 Carcinoid syndrome	0.593	0.407	0.000
E03.8 Other specified hypothyroidism	0.593	0.407	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.593	0.407	0.000
K12.1 Other forms of stomatitis	0.590	0.410	0.000
K14 Diseases of tongue	0.590	0.410	0.000
K52.8 Other specified non-infective gastro-enteritis and colitis	0.588	0.412	0.000
D50.8 Other iron deficiency anaemias	0.588	0.412	0.000
E13.8 With unspecified complications	0.586	0.414	0.000
E13.7 With multiple complications	0.586	0.414	0.000
E13.6 With other specified complications	0.586	0.414	0.000
E13.5 With peripheral circulatory complications	0.586	0.414	0.000
E13.4 With neurological complications	0.586	0.414	0.000
E13.3 With ophthalmic complications	0.586	0.414	0.000
E13.2 With renal complications	0.586	0.414	0.000
E13.1 With ketoacidosis	0.586	0.414	0.000
E13.0 With coma	0.586	0.414	0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.585	0.415	0.000
K06.8 Other specified disorders of gingiva and edentulous alveolar ridge	0.585	0.415	0.000
E06 Thyroiditis	0.582	0.418	0.000
K04.0 Pulpitis	0.581	0.418	0.000
E26.0 Primary hyperaldosteronism	0.577	0.423	0.000
K52.9 Non-infective gastro-enteritis and colitis, unspecified	0.576	0.424	0.000
E23.0 Hypopituitarism	0.575	0.425	0.000
K13.5 Oral submucous fibrosis	0.574	0.426	0.000
E34.9 Endocrine disorder, unspecified	0.566	0.434	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.566	0.434	0.000
E22.8 Other hyperfunction of pituitary gland	0.566	0.434	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.563	0.437	0.000
E23.1 Drug-induced hypopituitarism	0.563	0.437	0.000
K07.2 Anomalies of dental arch relationship	0.550	0.450	0.000
E34.8 Other specified endocrine disorders	0.548	0.452	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.548	0.452	0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.547	0.453	0.000
K00.9 Disorder of tooth development, unspecified	0.546	0.453	0.000
E15 Nondiabetic hypoglycaemic coma	0.545	0.455	0.000
K05.2 Acute periodontitis	0.545	0.455	0.000
K05.5 Other periodontal diseases	0.545	0.455	0.000
K05.0 Acute gingivitis	0.545	0.455	0.000
E34.5 Androgen resistance syndrome	0.545	0.455	0.000
E34.4 Constitutional tall stature	0.545	0.455	0.000
E34.3 Short stature, not elsewhere classified	0.545	0.455	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.545	0.455	0.000
E34.1 Other hypersecretion of intestinal hormones	0.545	0.455	0.000
E61 Deficiency of other nutrient elements	0.543	0.457	0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)	0.540	0.460	0.000
E07.8 Other specified disorders of thyroid	0.540	0.460	0.000
E14.8 With unspecified complications	0.540	0.460	0.000
E14.7 With multiple complications	0.540	0.460	0.000
E14.6 With other specified complications	0.540	0.460	0.000
E14.5 With peripheral circulatory complications	0.540	0.460	0.000
E14.2 Withrenal complications	0.540	0.460	0.000
E14.0 With coma	0.540	0.460	0.000
E23.2 Diabetes insipidus	0.540	0.460	0.000
K00.8 Other disorders of tooth development	0.539	0.461	0.000
K00.7 Teething syndrome	0.539	0.461	0.000
K00.5 Hereditary disturbances in tooth structure, not elsewhere classified	0.539	0.461	0.000
K00.4 Disturbances in tooth formation	0.539	0.461	0.000
K00.3 Mottled teeth	0.539	0.461	0.000
K00.2 Abnormalities of size and form of teeth	0.539	0.461	0.000
K13.2 Leukoplakia and other disturbances of oral epithelium, including tongue	0.537	0.462	0.000
K13.3 Hairy leukoplakia	0.537	0.462	0.000
K13.1 Cheek and lip biting	0.537	0.462	0.000
E28.9 Ovarian dysfunction, unspecified	0.534	0.466	0.000
E28.8 Other ovarian dysfunction	0.534	0.466	0.000
E28.1 Androgen excess	0.534	0.466	0.000
E28.0 Oestrogen excess	0.534	0.466	0.000
K11.7 Disturbances of salivary secretion	0.532	0.467	0.000
E26.9 Hyperaldosteronism, unspecified	0.530	0.470	0.000
E26.8 Other hyperaldosteronism	0.530	0.470	0.000
E26.1 Secondary hyperaldosteronism	0.530	0.470	0.000
E56 Other vitamin deficiencies	0.526	0.474	0.000
K09 Cysts of oral region, not elsewhere classified	0.526	0.474	0.000
K51.0 Ulcerative (chronic) enterocolitis	0.524	0.476	0.000
K51.3 Ulcerative (chronic) rectosigmoiditis	0.522	0.478	0.000
K07.4 Malocclusion, unspecified	0.515	0.484	0.000
E27.2 Addisonian crisis	0.515	0.485	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.513	0.487	0.000
K12.2 Cellulitis and abscess of mouth	0.512	0.488	0.000
K04.4 Acute apical periodontitis of pulpal origin	0.512	0.488	0.000
E27.1 Primary adrenocortical insufficiency	0.510	0.490	0.000
E07.1 Dyshormogenetic goitre	0.509	0.491	0.000
E07.0 Hypersecretion of calcitonin	0.509	0.491	0.000
K91.4 Colostomy and enterostomy malfunction	0.508	0.492	0.000
K00.6 Disturbances in tooth eruption	0.508	0.492	0.000
K14.8 Other diseases of tongue	0.507	0.493	0.000
K52.2 Allergic and dietetic gastro-enteritis and colitis	0.500	0.500	0.000
E07.9 Disorder of thyroid, unspecified	0.497	0.503	0.000
E25.9 Adrenogenital disorder, unspecified	0.496	0.503	0.000
E25.8 Other adrenogenital disorders	0.496	0.503	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.496	0.503	0.000
E30.9 Disorder of puberty, unspecified	0.496	0.503	0.000
E30.8 Other disorders of puberty	0.496	0.503	0.000
E30.1 Precocious puberty	0.496	0.503	0.000
E30.0 Delayed puberty	0.496	0.503	0.000
E31.9 Polyglandular dysfunction, unspecified	0.496	0.503	0.000
E31.8 Other polyglandular dysfunction	0.496	0.503	0.000
E31.1 Polyglandular hyperfunction	0.496	0.503	0.000
E31.0 Autoimmune polyglandular failure	0.496	0.503	0.000
E32.9 Disease of thymus, unspecified	0.496	0.503	0.000
E32.8 Other diseases of thymus	0.496	0.503	0.000
E32.1 Abscess of thymus	0.496	0.503	0.000
E32.0 Persistent hyperplasia of thymus	0.496	0.503	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.496	0.503	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.496	0.503	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.496	0.503	0.000
E12.9 Without complications	0.496	0.504	0.000
E12.8 With unspecified complications	0.496	0.504	0.000
E12.7 With multiple complications	0.496	0.504	0.000
E12.6 With other specified complications	0.496	0.504	0.000
E12.5 With peripheral circulatory complications	0.496	0.504	0.000
E12.4 With neurological complications	0.496	0.504	0.000
E12.3 With ophthalmic complications	0.496	0.504	0.000
E12.2 With renal complications	0.496	0.504	0.000
E12.1 With ketoacidosis	0.496	0.504	0.000
E12.0 With coma	0.496	0.504	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.495	0.505	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.495	0.505	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.495	0.505	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.495	0.505	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.495	0.505	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.495	0.505	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.495	0.505	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.495	0.505	0.000
E14.4 With neurological complications	0.491	0.509	0.000
E16.2 Hypoglycaemia, unspecified	0.491	0.509	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.491	0.509	0.000
E63 Other nutritional deficiencies	0.491	0.509	0.000
E51 Thiamine deficiency	0.491	0.509	0.000
E50 Vitamin A deficiency	0.491	0.509	0.000
E60 Dietary zinc deficiency	0.491	0.509	0.000
E59 Dietary selenium deficiency	0.491	0.509	0.000
E58 Dietary calcium deficiency	0.491	0.509	0.000
E54 Ascorbic acid deficiency	0.491	0.509	0.000
E52 Niacin deficiency [pellagra]	0.491	0.509	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.490	0.509	0.000
E45 Retarded development following protein-energy malnutrition	0.490	0.509	0.000
E43 Unspecified severe protein-energy malnutrition	0.490	0.509	0.000
E42 Marasmic kwashiorkor	0.490	0.509	0.000
E41 Nutritional marasmus	0.490	0.509	0.000
E40 Kwashiorkor	0.490	0.509	0.000
K51.5 Mucosal proctocolitis	0.489	0.511	0.000
K52.0 Gastro-enteritis and colitis due to radiation	0.485	0.515	0.000
K04.3 Abnormal hard tissue formation in pulp	0.483	0.517	0.000
K04.2 Pulp degeneration	0.483	0.517	0.000
K04.1 Necrosis of pulp	0.483	0.517	0.000
E46 Unspecified protein-energy malnutrition	0.481	0.519	0.000
K35-K38 Diseases of appendix	0.477	0.523	0.000
K10.2 Inflammatory conditions of jaws	0.476	0.524	0.000
D52 Folate deficiency anaemia	0.476	0.524	0.000
E16.1 Other hypoglycaemia	0.475	0.525	0.000
E28.3 Primary ovarian failure	0.474	0.526	0.000
K03.6 Deposits [accretions] on teeth	0.474	0.526	0.000
E53 Deficiency of other B group vitamins	0.470	0.530	0.000
K04.9 Other and unspecified diseases of pulp and periapical tissues	0.469	0.530	0.000
K06.0 Gingival recession	0.463	0.537	0.000
D53 Other nutritional anaemias	0.458	0.542	0.000
K91.2 Postsurgical malabsorption, not elsewhere classified	0.457	0.543	0.000
K03.9 Disease of hard tissues of teeth, unspecified	0.455	0.545	0.000
K03.8 Other specified diseases of hard tissues of teeth	0.455	0.545	0.000
K03.7 Posteruptive colour changes of dental hard tissues	0.455	0.545	0.000
K03.5 Ankylosis of teeth	0.455	0.545	0.000
K03.4 Hypercementosis	0.455	0.545	0.000
K03.3 Pathological resorption of teeth	0.455	0.545	0.000
K03.2 Erosion of teeth	0.455	0.545	0.000
K03.1 Abrasion of teeth	0.455	0.545	0.000
K03.0 Excessive attrition of teeth	0.455	0.545	0.000
D50.1 Sideropenic dysphagia	0.451	0.549	0.000
E20.8 Other hypoparathyroidism	0.448	0.552	0.000
E20.1 Pseudohypoparathyroidism	0.448	0.552	0.000
E20.0 Idiopathic hypoparathyroidism	0.448	0.552	0.000
K10.8 Other specified diseases of jaws	0.446	0.554	0.000
D51.8 Other vitamin B12 deficiency anaemias	0.444	0.556	0.000
D51.3 Other dietary vitamin B12 deficiency anaemia	0.444	0.556	0.000
D51.2 Transcobalamin II deficiency	0.444	0.556	0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.444	0.556	0.000
K36 Other appendicitis	0.444	0.556	0.000
E61.1 Iron deficiency	0.442	0.558	0.000
K52.3 Indeterminate colitis	0.441	0.559	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.439	0.561	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.439	0.561	0.000
E16.4 Abnormal secretion of gastrin	0.439	0.561	0.000
E16.3 Increased secretion of glucagon	0.439	0.561	0.000
K10.9 Disease of jaws, unspecified	0.438	0.562	0.000
K10.3 Alveolitis of jaws	0.438	0.562	0.000
K10.1 Giant cell granuloma, central	0.438	0.562	0.000
E06.3 Autoimmune thyroiditis	0.436	0.564	0.000
K09.8 Other cysts of oral region, not elsewhere classified	0.436	0.564	0.000
K14.6 Glossodynia	0.434	0.566	0.000
K06.9 Disorder of gingiva and edentulous alveolar ridge, unspecified	0.432	0.568	0.000
K13.6 Irritative hyperplasia of oral mucosa	0.432	0.568	0.000
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere	0.432	0.568	0.000
K93.1 Megacolon in Chagas' disease	0.432	0.568	0.000
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands	0.432	0.568	0.000
E11 Non-insulin-dependent diabetes mellitus	0.426	0.574	0.000
K14.5 Plicated tongue	0.423	0.577	0.000
K14.4 Atrophy of tongue papillae	0.423	0.577	0.000
K14.3 Hypertrophy of tongue papillae	0.423	0.577	0.000
K14.2 Median rhomboid glossitis	0.423	0.577	0.000
K14.1 Geographic tongue	0.423	0.577	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.423	0.577	0.000
K09.1 Developmental (nonodontogenic) cysts of oral region	0.418	0.582	0.000
E06.5 Other chronic thyroiditis	0.417	0.583	0.000
E06.4 Drug-induced thyroiditis	0.417	0.583	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.417	0.583	0.000
E06.1 Subacute thyroiditis	0.417	0.583	0.000
E06.0 Acute thyroiditis	0.417	0.583	0.000
K04.5 Chronic apical periodontitis	0.417	0.583	0.000
E56.1 Deficiency of vitamin K	0.413	0.587	0.000
E11.6 With other specified complications	0.393	0.607	0.000
K91.9 Postprocedural disorder of digestive system, unspecified	0.392	0.607	0.000
K06.1 Gingival enlargement	0.391	0.608	0.000
K05.22 Aggressive periodontitis, generalized	0.391	0.609	0.000
K14.9 Disease of tongue, unspecified	0.390	0.610	0.000
E61.9 Deficiency of nutrient element, unspecified	0.389	0.611	0.000
E61.8 Deficiency of other specified nutrient elements	0.389	0.611	0.000
E61.7 Deficiency of multiple nutrient elements	0.389	0.611	0.000
E61.6 Vanadium deficiency	0.389	0.611	0.000
E61.5 Molybdenum deficiency	0.389	0.611	0.000
E61.4 Chromium deficiency	0.389	0.611	0.000
E61.3 Manganese deficiency	0.389	0.611	0.000
E61.2 Magnesium deficiency	0.389	0.611	0.000
E61.0 Copper deficiency	0.389	0.611	0.000
K13.29 Other disturbances of oral epithelium, including tongue	0.385	0.614	0.000
K91.0 Vomiting following gastro-intestinal surgery	0.382	0.618	0.000
K91.5 Postcholecystectomy syndrome	0.381	0.619	0.000
E20.9 Hypoparathyroidism, unspecified	0.380	0.620	0.000
E56.9 Vitamin deficiency, unspecified	0.377	0.622	0.000
E56.8 Deficiency of other vitamins	0.377	0.622	0.000
E56.0 Deficiency of vitamin E	0.377	0.622	0.000
E55 Vitamin D deficiency	0.377	0.622	0.000
K10.0 Developmental disorders of jaws	0.373	0.627	0.000
D52.9 Folate deficiency anaemia, unspecified	0.372	0.628	0.000
K09.9 Cyst of oral region, unspecified	0.367	0.633	0.000
E53.9 Vitamin B deficiency, unspecified	0.366	0.634	0.000
E65-E68 Obesity and other hyperalimentation	0.365	0.635	0.000
K06.2 Gingival and edentulous alveolar ridge lesions associated with trauma	0.363	0.637	0.000
E11.3 With ophthalmic complications	0.360	0.640	0.000
E11.1 With ketoacidosis	0.356	0.644	0.000
K91.1 Postgastric surgery syndromes	0.353	0.647	0.000
E50.9 Vitamin A deficiency, unspecified	0.352	0.648	0.000
E50.8 Other manifestations of vitamin A deficiency	0.352	0.648	0.000
E50.7 Other ocular manifestations of vitamin A deficiency	0.352	0.648	0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.352	0.648	0.000
E50.5 Vitamin A deficiency with night blindness	0.352	0.648	0.000
E50.4 Vitamin A deficiency with keratomalacia	0.352	0.648	0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.352	0.648	0.000
E50.2 Vitamin A deficiency with corneal xerosis	0.352	0.648	0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.352	0.648	0.000
E50.0 Vitamin A deficiency with conjunctival xerosis	0.352	0.648	0.000
E51.9 Thiamine deficiency, unspecified	0.352	0.648	0.000
E51.8 Other manifestations of thiamine deficiency	0.352	0.648	0.000
E51.2 Wernicke's encephalopathy	0.352	0.648	0.000
E51.1 Beriberi	0.352	0.648	0.000
E63.9 Nutritional deficiency, unspecified	0.352	0.648	0.000
E63.8 Other specified nutritional deficiencies	0.352	0.648	0.000
E63.1 Imbalance of constituents of food intake	0.352	0.648	0.000
E63.0 Essential fatty acid [EFA] deficiency	0.352	0.648	0.000
E64.9 Sequelae of unspecified nutritional deficiency	0.352	0.648	0.000
E64.8 Sequelae of other nutritional deficiencies	0.352	0.648	0.000
E64.3 Sequelae of rickets	0.352	0.648	0.000
E64.2 Sequelae of vitamin C deficiency	0.352	0.648	0.000
E64.1 Sequelae of vitamin A deficiency	0.352	0.648	0.000
E64.0 Sequelae of protein-energy malnutrition	0.352	0.648	0.000
E44.1 Mild protein-energy malnutrition	0.352	0.648	0.000
E44.0 Moderate protein-energy malnutrition	0.352	0.648	0.000
D52.8 Other folate deficiency anaemias	0.341	0.659	0.000
D52.1 Drug-induced folate deficiency anaemia	0.341	0.659	0.000
D52.0 Dietary folate deficiency anaemia	0.341	0.659	0.000
D53.9 Nutritional anaemia, unspecified	0.341	0.659	0.000
K12.3 Oral mucositis (ulcerative)	0.338	0.661	0.000
E53.1 Pyridoxine deficiency	0.337	0.663	0.000
E53.0 Riboflavin deficiency	0.337	0.663	0.000
K05.3 Chronic periodontitis	0.333	0.667	0.000
D53.8 Other specified nutritional anaemias	0.328	0.672	0.000
D53.2 Scorbutic anaemia	0.328	0.672	0.000
D53.1 Other megaloblastic anaemias, not elsewhere classified	0.328	0.672	0.000
D53.0 Protein deficiency anaemia	0.328	0.672	0.000
E11.8 With unspecified complications	0.322	0.678	0.000
K13.0 Diseases of lips	0.321	0.679	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.312	0.688	0.000
K38 Other diseases of appendix	0.306	0.694	0.000
E11.7 With multiple complications	0.306	0.694	0.000
E11.0 With coma	0.285	0.715	0.000
K02 Dental caries	0.279	0.721	0.000
E06.9 Thyroiditis, unspecified	0.274	0.726	0.001
E53.8 Deficiency of other specified B group vitamins	0.273	0.727	0.000
E55.0 Rickets, active	0.271	0.729	0.000
K52.1 Toxic gastro-enteritis and colitis	0.266	0.734	0.001
E67 Other hyperalimentation	0.262	0.738	0.000
E68 Sequelae of hyperalimentation	0.262	0.738	0.000
K51.2 Ulcerative (chronic) proctitis	0.261	0.739	0.000
K09.0 Developmental odontogenic cysts	0.259	0.740	0.000
E04 Other non-toxic goitre	0.256	0.744	0.000
K01 Embedded and impacted teeth	0.248	0.751	0.000
K14.0 Glossitis	0.245	0.754	0.000
K65-K67 Diseases of peritoneum	0.245	0.755	0.000
K09.2 Other cysts of jaw	0.243	0.756	0.000
K04.7 Periapical abscess without sinus	0.243	0.757	0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.236	0.764	0.000
K04.6 Periapical abscess with sinus	0.224	0.775	0.001
E65 Localised adiposity	0.224	0.776	0.000
E05.5 Thyroid crisis or storm	0.224	0.776	0.000
E05.4 Thyrotoxicosis factitia	0.224	0.776	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.224	0.776	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.224	0.776	0.000
E11.5 With peripheral circulatory complications	0.223	0.777	0.000
E05.8 Other thyrotoxicosis	0.223	0.777	0.000
K38.3 Fistula of appendix	0.219	0.780	0.000
K38.2 Diverticulum of appendix	0.219	0.780	0.000
K38.0 Hyperplasia of appendix	0.219	0.780	0.000
K38.8 Other specified diseases of appendix	0.219	0.781	0.000
K92 Other diseases of digestive system	0.219	0.781	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.216	0.784	0.000
K38.9 Disease of appendix, unspecified	0.213	0.787	0.000
K08 Other disorders of teeth and supporting structures	0.211	0.789	0.000
E04.0 Non-toxic diffuse goitre	0.207	0.793	0.000
K02.5 Caries with pulp exposure	0.200	0.800	0.000
K02.4 Odontoclasia	0.200	0.800	0.000
K02.3 Arrested dental caries	0.200	0.800	0.000
K02.2 Caries of cementum	0.200	0.800	0.000
K02.0 Caries limited to enamel	0.200	0.800	0.000
K02.1 Caries of dentin	0.200	0.800	0.000
K38.1 Appendicular concretions	0.193	0.807	0.000
# Top node	0.189	0.811	0.000
E67.8 Other specified hyperalimentation	0.188	0.812	0.000
E67.3 Hypervitaminosis D	0.188	0.812	0.000
E67.2 Megavitamin-B6 syndrome	0.188	0.812	0.000
E67.1 Hypercarotenaemia	0.188	0.812	0.000
E67.0 Hypervitaminosis A	0.188	0.812	0.000
E04.8 Other specified non-toxic goitre	0.183	0.816	0.000
E11.2 With renal complications	0.183	0.817	0.000
K92.8 Other specified diseases of digestive system	0.180	0.820	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.178	0.822	0.000
D80-D89 Certain disorders involving the immune mechanism	0.177	0.823	0.000
K67 Disorders of peritoneum in infectious diseases classified elsewhere	0.175	0.824	0.000
K37 Unspecified appendicitis	0.174	0.826	0.000
E70-E90 Metabolic disorders	0.172	0.828	0.000
E14.3 With ophthalmic complications	0.169	0.830	0.001
E05.9 Thyrotoxicosis, unspecified	0.170	0.830	0.000
E55.9 Vitamin D deficiency, unspecified	0.157	0.842	0.000
E83 Disorders of mineral metabolism	0.157	0.843	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.155	0.845	0.000
K92.2 Gastro-intestinal haemorrhage, unspecified	0.153	0.847	0.000
K08.0 Exfoliation of teeth due to systemic causes	0.151	0.849	0.000
E83.1 Disorders of iron metabolism	0.151	0.849	0.000
E85 Amyloidosis	0.151	0.849	0.000
D55-D59 Haemolytic anaemias	0.149	0.851	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.141	0.859	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.141	0.859	0.000
G30 Alzheimer's disease	0.136	0.864	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.136	0.864	0.000
G30.9 Alzheimer's disease, unspecified	0.135	0.865	0.000
G30-G32 Other degenerative diseases of the nervous system	0.135	0.865	0.000
K92.9 Disease of digestive system, unspecified	0.134	0.866	0.000
K02.8 Other dental caries	0.133	0.867	0.000
D84 Other immunodeficiencies	0.132	0.868	0.000
D80 Immunodeficiency with predominantly antibody defects	0.131	0.868	0.000
D83 Common variable immunodeficiency	0.131	0.869	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations