TreeWAS – Variant ID: rs8135665

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
D05.9 Carcinoma in situ of breast, unspecified	0.230	0.770	0.000
D05 Carcinoma in situ of breast	0.221	0.779	0.000
D05.1 Intraductal carcinoma in situ	0.215	0.785	0.000
D05.7 Other carcinoma in situ of breast	0.179	0.821	0.000
Z85.3 Personal history of malignant neoplasm of breast	0.162	0.838	0.000
D09.0 Bladder	0.155	0.845	0.000
D00-D09 In situ neoplasms	0.154	0.846	0.000
D09 Carcinoma in situ of other and unspecified sites	0.153	0.847	0.000
D05.0 Lobular carcinoma in situ	0.132	0.867	0.000
D02 Carcinoma in situ of middle ear and respiratory system	0.129	0.871	0.000
D03 Melanoma in situ	0.127	0.873	0.000
D03.5 Melanoma in situ of trunk	0.113	0.887	0.000
D02.0 Larynx	0.112	0.888	0.000
D09.9 Carcinoma in situ, unspecified	0.110	0.890	0.000
D09.7 Carcinoma in situ of other specified sites	0.110	0.890	0.000
D09.3 Thyroid and other endocrine glands	0.110	0.890	0.000
D09.2 Eye	0.110	0.890	0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.106	0.893	0.000
D03.2 Melanoma in situ of ear and external auricular canal	0.102	0.898	0.000
D03.6 Melanoma in situ of upper limb, including shoulder	0.100	0.900	0.000
D01 Carcinoma in situ of other and unspecified digestive organs	0.099	0.900	0.000
D09.1 Other and unspecified urinary organs	0.099	0.901	0.000
D02.4 Respiratory system, unspecified	0.093	0.907	0.000
D02.3 Other parts of respiratory system	0.093	0.907	0.000
D02.2 Bronchus and lung	0.093	0.907	0.000
D02.1 Trachea	0.093	0.907	0.000
D03.7 Melanoma in situ of lower limb, including hip	0.093	0.907	0.000
D03.9 Melanoma in situ, unspecified	0.091	0.909	0.000
D03.8 Melanoma in situ of other sites	0.091	0.909	0.000
D03.1 Melanoma in situ of eyelid, including canthus	0.091	0.909	0.000
D03.0 Melanoma in situ of lip	0.091	0.909	0.000
D07 Carcinoma in situ of other and unspecified genital organs	0.081	0.919	0.000
D06 Carcinoma in situ of cervix uteri	0.077	0.923	0.000
D00.2 Stomach	0.076	0.923	0.000
D00.1 Oesophagus	0.076	0.923	0.000
D03.4 Melanoma in situ of scalp and neck	0.076	0.924	0.000
D00.0 Lip, oral cavity and pharynx	0.073	0.927	0.000
D01.9 Digestive organ, unspecified	0.071	0.928	0.000
D01.7 Other specified digestive organs	0.071	0.928	0.000
D01.5 Liver, gallbladder and bile ducts	0.071	0.928	0.000
D01.4 Other and unspecified parts of intestine	0.071	0.928	0.000
D01.1 Rectosigmoid junction	0.071	0.928	0.000
D01.2 Rectum	0.071	0.929	0.000
D01.0 Colon	0.067	0.933	0.000
D01.3 Anus and anal canal	0.066	0.934	0.000
D07.1 Vulva	0.063	0.937	0.000
D07.6 Other and unspecified male genital organs	0.058	0.942	0.000
D07.3 Other and unspecified female genital organs	0.058	0.942	0.000
D07.0 Endometrium	0.058	0.942	0.000
D06.0 Endocervix	0.058	0.942	0.000
D07.2 Vagina	0.057	0.943	0.000
D06.7 Other parts of cervix	0.055	0.945	0.000
D06.1 Exocervix	0.055	0.945	0.000
D03.3 Melanoma in situ of other and unspecified parts of face	0.054	0.945	0.000
D07.4 Penis	0.054	0.946	0.000
M79.79 Fibromyalgia (Site unspecified)	0.028	0.972	0.000
D07.5 Prostate	0.027	0.972	0.000
E21.0 Primary hyperparathyroidism	0.025	0.975	0.000
S02.20 Fracture of nasal bones (closed)	0.019	0.981	0.000
S22.30 Fracture of rib (closed)	0.000	0.985	0.015
W07.0 Home	0.000	0.985	0.015
D04 Carcinoma in situ of skin	0.014	0.985	0.001
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.015	0.985	0.000
D06.9 Cervix, unspecified	0.014	0.986	0.000
M79.7 Fibromyalgia	0.014	0.986	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.013	0.987	0.000
S72.10 Pertrochanteric fracture (closed)	0.000	0.988	0.012
D04.6 Skin of upper limb, including shoulder	0.011	0.989	0.001
Z72.1 Alcohol use	0.011	0.989	0.000
M79.70 Fibromyalgia (Multiple sites)	0.011	0.989	0.000
R09.1 Pleurisy	0.011	0.989	0.000
D04.8 Skin of other sites	0.010	0.989	0.001
D04.0 Skin of lip	0.010	0.989	0.001
E21.5 Disorder of parathyroid gland, unspecified	0.011	0.989	0.000
E21.4 Other specified disorders of parathyroid gland	0.011	0.989	0.000
E21.2 Other hyperparathyroidism	0.011	0.989	0.000
H71 Cholesteatoma of middle ear	0.010	0.990	0.000
M79.78 Fibromyalgia (Other)	0.010	0.990	0.000
M79.77 Fibromyalgia (Ankle and foot)	0.010	0.990	0.000
M79.76 Fibromyalgia (Lower leg)	0.010	0.990	0.000
M79.75 Fibromyalgia (Pelvic region and thigh)	0.010	0.990	0.000
M79.74 Fibromyalgia (Hand)	0.010	0.990	0.000
M79.73 Fibromyalgia (Forearm)	0.010	0.990	0.000
M79.72 Fibromyalgia (Upper arm)	0.010	0.990	0.000
M79.71 Fibromyalgia (Shoulder region)	0.010	0.990	0.000
D04.1 Skin of eyelid, including canthus	0.009	0.990	0.001
S72.1 Pertrochanteric fracture	0.000	0.990	0.010
D04.9 Skin, unspecified	0.009	0.990	0.001
D04.4 Skin of scalp and neck	0.009	0.990	0.001
S02.2 Fracture of nasal bones	0.010	0.990	0.000
M81.9 Osteoporosis, unspecified	0.010	0.990	0.000
E21.3 Hyperparathyroidism, unspecified	0.009	0.991	0.000
S73.0 Dislocation of hip	0.000	0.991	0.009
M81.98 Osteoporosis, unspecified (Other)	0.009	0.991	0.000
M81.99 Osteoporosis, unspecified (Site unspecified)	0.009	0.991	0.000
D04.2 Skin of ear and external auricular canal	0.008	0.991	0.001
M81.90 Osteoporosis, unspecified (Multiple sites)	0.009	0.991	0.000
S72 Fracture of femur	0.000	0.991	0.008
M81.96 Osteoporosis, unspecified (Lower leg)	0.008	0.992	0.000
M25.54 Pain in joint (Hand)	0.008	0.992	0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.000	0.992	0.008
H65-H75 Diseases of middle ear and mastoid	0.008	0.992	0.000
N80.9 Endometriosis, unspecified	0.008	0.992	0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.008	0.992	0.000
H73.8 Other specified disorders of tympanic membrane	0.008	0.992	0.000
S02.21 Fracture of nasal bones (open)	0.008	0.992	0.000
H73 Other disorders of tympanic membrane	0.008	0.992	0.000
H66 Suppurative and unspecified otitis media	0.008	0.992	0.000
M81.94 Osteoporosis, unspecified (Hand)	0.008	0.992	0.000
S72.3 Fracture of shaft of femur	0.000	0.992	0.008
H72 Perforation of tympanic membrane	0.008	0.992	0.000
Z94.8 Other transplanted organ and tissue status	0.000	0.992	0.008
S70-S79 Injuries to the hip and thigh	0.000	0.992	0.008
F10.2 Dependence syndrome	0.008	0.992	0.000
S72.4 Fracture of lower end of femur	0.000	0.992	0.007
H72.9 Perforation of tympanic membrane, unspecified	0.008	0.992	0.000
H66.9 Otitis media, unspecified	0.007	0.993	0.000
S22.3 Fracture of rib	0.000	0.993	0.007
S72.11 Pertrochanteric fracture (open)	0.000	0.993	0.007
M81.93 Osteoporosis, unspecified (Forearm)	0.007	0.993	0.000
M81.92 Osteoporosis, unspecified (Upper arm)	0.007	0.993	0.000
M81.91 Osteoporosis, unspecified (Shoulder region)	0.007	0.993	0.000
S72.30 Fracture of shaft of femur (closed)	0.000	0.993	0.007
S72.40 Fracture of lower end of femur (closed)	0.000	0.993	0.007
G56.2 Lesion of ulnar nerve	0.007	0.993	0.000
G62.9 Polyneuropathy, unspecified	0.007	0.993	0.000
G56.8 Other mononeuropathies of upper limb	0.007	0.993	0.000
S70 Superficial injury of hip and thigh	0.000	0.993	0.007
D04.5 Skin of trunk	0.005	0.993	0.001
S70.1 Contusion of thigh	0.000	0.993	0.007
H73.1 Chronic myringitis	0.006	0.994	0.000
S72.7 Multiple fractures of femur	0.000	0.994	0.006
S79 Other and unspecified injuries of hip and thigh	0.000	0.994	0.006
H66.3 Other chronic suppurative otitis media	0.006	0.994	0.000
S70.9 Superficial injury of hip and thigh, unspecified	0.000	0.994	0.006
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.006	0.994	0.000
H68 Eustachian salpingitis and obstruction	0.006	0.994	0.000
H67 Otitis media in diseases classified elsewhere	0.006	0.994	0.000
H66.4 Suppurative otitis media, unspecified	0.006	0.994	0.000
F10 Mental and behavioural disorders due to use of alcohol	0.006	0.994	0.000
D04.7 Skin of lower limb, including hip	0.005	0.994	0.001
D61.9 Aplastic anaemia, unspecified	0.000	0.994	0.006
F10.3 Withdrawal state	0.006	0.994	0.000
H72.8 Other perforations of tympanic membrane	0.006	0.994	0.000
H73.0 Acute myringitis	0.006	0.994	0.000
H70 Mastoiditis and related conditions	0.006	0.994	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.006	0.994	0.000
H66.0 Acute suppurative otitis media	0.006	0.994	0.000
H72.2 Other marginal perforations of tympanic membrane	0.006	0.994	0.000
S72.9 Fracture of femur, part unspecified	0.000	0.994	0.006
H72.1 Attic perforation of tympanic membrane	0.006	0.994	0.000
S72.31 Fracture of shaft of femur (open)	0.000	0.994	0.006
H66.1 Chronic tubotympanic suppurative otitis media	0.006	0.994	0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.006	0.994	0.000
S78 Traumatic amputation of hip and thigh	0.000	0.994	0.006
S77 Crushing injury of hip and thigh	0.000	0.994	0.006
S75 Injury of blood vessels at hip and thigh level	0.000	0.994	0.006
S74 Injury of nerves at hip and thigh level	0.000	0.994	0.006
F10.5 Psychotic disorder	0.006	0.994	0.000
F10.0 Acute intoxication	0.006	0.994	0.000
S22.31 Fracture of rib (open)	0.000	0.994	0.005
S76 Injury of muscle and tendon at hip and thigh level	0.000	0.994	0.006
S72.8 Fractures of other parts of femur	0.000	0.994	0.005
G56 Mononeuropathies of upper limb	0.006	0.994	0.000
W07 Fall involving chair	0.000	0.994	0.006
S73.1 Sprain and strain of hip	0.000	0.994	0.005
S72.2 Subtrochanteric fracture	0.000	0.994	0.005
D04.3 Skin of other and unspecified parts of face	0.004	0.994	0.001
H72.0 Central perforation of tympanic membrane	0.005	0.995	0.000
S79.9 Unspecified injury of hip and thigh	0.000	0.995	0.005
S72.41 Fracture of lower end of femur (open)	0.000	0.995	0.005
G56.9 Mononeuropathy of upper limb, unspecified	0.005	0.995	0.000
S70.7 Multiple superficial injuries of hip and thigh	0.000	0.995	0.005
F10.6 Amnesic syndrome	0.005	0.995	0.000
H74 Other disorders of middle ear and mastoid	0.005	0.995	0.000
M81 Osteoporosis without pathological fracture	0.005	0.995	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.005	0.995	0.000
S79.8 Other specified injuries of hip and thigh	0.000	0.995	0.005
S72.71 Multiple fractures of femur (open)	0.000	0.995	0.005
S72.70 Multiple fractures of femur (closed)	0.000	0.995	0.005
S71 Open wound of hip and thigh	0.000	0.995	0.005
S72.0 Fracture of neck of femur	0.000	0.995	0.005
S79.7 Multiple injuries of hip and thigh	0.000	0.995	0.005
F10.7 Residual and late-onset psychotic disorder	0.005	0.995	0.000
B91 Sequelae of poliomyelitis	0.005	0.995	0.000
H67.8 Otitis media in other diseases classified elsewhere	0.004	0.995	0.000
H67.1 Otitis media in viral diseases classified elsewhere	0.004	0.995	0.000
H67.0 Otitis media in bacterial diseases classified elsewhere	0.004	0.995	0.000
H68.1 Obstruction of Eustachian tube	0.004	0.995	0.000
H68.0 Eustachian salpingitis	0.004	0.995	0.000
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.004	0.995	0.000
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.004	0.995	0.000
F10.8 Other mental and behavioural disorders	0.004	0.995	0.000
H70.8 Other mastoiditis and related conditions	0.004	0.995	0.000
H70.2 Petrositis	0.004	0.995	0.000
H70.1 Chronic mastoiditis	0.004	0.995	0.000
H70.0 Acute mastoiditis	0.004	0.995	0.000
S72.91 Fracture of femur, part unspecified (open)	0.000	0.996	0.004
G56.4 Causalgia	0.004	0.996	0.000
S70.0 Contusion of hip	0.000	0.996	0.004
C20 Malignant neoplasm of rectum	0.004	0.996	0.000
S74.9 Injury of unspecified nerve at hip and thigh level	0.000	0.996	0.004
S74.8 Injury of other nerves at hip and thigh level	0.000	0.996	0.004
S74.7 Injury of multiple nerves at hip and thigh level	0.000	0.996	0.004
S74.2 Injury of cutaneous sensory nerve at hip and thigh level	0.000	0.996	0.004
S74.1 Injury of femoral nerve at hip and thigh level	0.000	0.996	0.004
S74.0 Injury of sciatic nerve at hip and thigh level	0.000	0.996	0.004
S75.9 Injury of unspecified blood vessel at hip and thigh level	0.000	0.996	0.004
S75.8 Injury of other blood vessels at hip and thigh level	0.000	0.996	0.004
S75.7 Injury of multiple blood vessels at hip and thigh level	0.000	0.996	0.004
S75.2 Injury of greater saphenous vein at hip and thigh level	0.000	0.996	0.004
S75.1 Injury of femoral vein at hip and thigh level	0.000	0.996	0.004
S75.0 Injury of femoral artery	0.000	0.996	0.004
S77.2 Crushing injury of hip with thigh	0.000	0.996	0.004
S77.1 Crushing injury of thigh	0.000	0.996	0.004
S77.0 Crushing injury of hip	0.000	0.996	0.004
S78.9 Traumatic amputation of hip and thigh, level unspecified	0.000	0.996	0.004
S78.1 Traumatic amputation at level between hip and knee	0.000	0.996	0.004
S78.0 Traumatic amputation at hip joint	0.000	0.996	0.004
H74.4 Polyp of middle ear	0.004	0.996	0.000
S76.1 Injury of quadriceps muscle and tendon	0.000	0.996	0.004
S76.7 Injury of multiple muscles and tendons at hip and thigh level	0.000	0.996	0.004
S76.3 Injury of muscle and tendon of the posterior muscle group at thigh level	0.000	0.996	0.004
S76.2 Injury of adductor muscle and tendon of thigh	0.000	0.996	0.004
S76.0 Injury of muscle and tendon of hip	0.000	0.996	0.004
S72.81 Fractures of other parts of femur (open)	0.000	0.996	0.004
W07.2 School, other institution and public administrative area	0.000	0.996	0.004
W07.8 Other specified place	0.000	0.996	0.004
W07.7 Farm	0.000	0.996	0.004
W07.6 Industrial and construction area	0.000	0.996	0.004
W07.5 Trade and service area	0.000	0.996	0.004
W07.4 Street and highway	0.000	0.996	0.004
W07.3 Sports and athletics area	0.000	0.996	0.004
S72.21 Subtrochanteric fracture (open)	0.000	0.996	0.004
G56.1 Other lesions of median nerve	0.004	0.996	0.000
S76.4 Injury of other and unspecified muscles and tendons at thigh level	0.000	0.996	0.004
W07.9 Unspecified place	0.000	0.996	0.004
H70.9 Mastoiditis, unspecified	0.004	0.996	0.000
F10.9 Unspecified mental and behavioural disorder	0.004	0.996	0.000
H65 Nonsuppurative otitis media	0.004	0.996	0.000
H40.1 Primary open-angle glaucoma	0.004	0.996	0.000
H69 Other disorders of Eustachian tube	0.004	0.996	0.000
G56.3 Lesion of radial nerve	0.004	0.996	0.000
Z99.1 Dependence on respirator	0.000	0.996	0.004
F10.4 Withdrawal state with delirium	0.004	0.996	0.000
H74.0 Tympanosclerosis	0.004	0.996	0.000
S72.90 Fracture of femur, part unspecified (closed)	0.000	0.996	0.004
M81.2 Osteoporosis of disuse	0.004	0.996	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.004	0.996	0.000
M81.8 Other osteoporosis	0.004	0.996	0.000
M81.6 Localised osteoporosis [Lequesne]	0.004	0.996	0.000
M81.5 Idiopathic osteoporosis	0.004	0.996	0.000
M81.1 Postoophorectomy osteoporosis	0.004	0.996	0.000
M81.0 Postmenopausal osteoporosis	0.004	0.996	0.000
M81.3 Postsurgical malabsorption osteoporosis	0.004	0.996	0.000
H74.1 Adhesive middle ear disease	0.004	0.996	0.000
W07.1 Residential institution	0.000	0.996	0.004
S71.8 Open wound of other and unspecified parts of pelvic girdle	0.000	0.996	0.003
S71.7 Multiple open wounds of of hip and thigh	0.000	0.996	0.003
S72.01 Fracture of neck of femur (open)	0.000	0.996	0.004
H65.0 Acute serous otitis media	0.004	0.996	0.000
H53.8 Other visual disturbances	0.000	0.996	0.004
S72.80 Fractures of other parts of femur (closed)	0.000	0.996	0.003
H65.1 Other acute nonsuppurative otitis media	0.003	0.996	0.000
I78.1 Naevus, nonneoplastic	0.004	0.996	0.000
M81.4 Drug-induced osteoporosis	0.003	0.996	0.000
S70.8 Other superficial injuries of hip and thigh	0.000	0.996	0.003
H74.2 Discontinuity and dislocation of ear ossicles	0.003	0.996	0.000
K22.2 Oesophageal obstruction	0.000	0.996	0.004
S76.10 Unspecified injury of quadriceps muscle, fascia and tendon	0.000	0.997	0.003
S72.20 Subtrochanteric fracture (closed)	0.000	0.997	0.003
W07.29 Fall involving chair; School, other institution and public administrative area; During unspecified activity	0.000	0.997	0.003
Z71.3 Dietary counselling and surveillance	0.000	0.997	0.003
S71.0 Open wound of hip	0.000	0.997	0.003
M67.43 Ganglion, wrist	0.003	0.997	0.000
S71.1 Open wound of thigh	0.000	0.997	0.003
H69.0 Patulous Eustachian tube	0.003	0.997	0.000
H65.4 Other chronic nonsuppurative otitis media	0.003	0.997	0.000
H65.3 Chronic mucoid otitis media	0.003	0.997	0.000
H74.3 Other acquired abnormalities of ear ossicles	0.003	0.997	0.000
M81.19 Postoophorectomy osteoporosis (Site unspecified)	0.003	0.997	0.000
M81.18 Postoophorectomy osteoporosis (Other)	0.003	0.997	0.000
M81.17 Postoophorectomy osteoporosis (Ankle and foot)	0.003	0.997	0.000
M81.16 Postoophorectomy osteoporosis (Lower leg)	0.003	0.997	0.000
M81.15 Postoophorectomy osteoporosis (Pelvic region and thigh)	0.003	0.997	0.000
M81.14 Postoophorectomy osteoporosis (Hand)	0.003	0.997	0.000
M81.13 Postoophorectomy osteoporosis (Forearm)	0.003	0.997	0.000
M81.12 Postoophorectomy osteoporosis (Upper arm)	0.003	0.997	0.000
M81.11 Postoophorectomy osteoporosis (Shoulder region)	0.003	0.997	0.000
M81.10 Postoophorectomy osteoporosis (Multiple sites)	0.003	0.997	0.000
M81.29 Osteoporosis of disuse (Site unspecified)	0.003	0.997	0.000
M81.28 Osteoporosis of disuse (Other)	0.003	0.997	0.000
M81.27 Osteoporosis of disuse (Ankle and foot)	0.003	0.997	0.000
M81.26 Osteoporosis of disuse (Lower leg)	0.003	0.997	0.000
M81.25 Osteoporosis of disuse (Pelvic region and thigh)	0.003	0.997	0.000
M81.24 Osteoporosis of disuse (Hand)	0.003	0.997	0.000
M81.23 Osteoporosis of disuse (Forearm)	0.003	0.997	0.000
M81.22 Osteoporosis of disuse (Upper arm)	0.003	0.997	0.000
M81.21 Osteoporosis of disuse (Shoulder region)	0.003	0.997	0.000
M81.20 Osteoporosis of disuse (Multiple sites)	0.003	0.997	0.000
M81.49 Drug-induced osteoporosis (Site unspecified)	0.003	0.997	0.000
M81.59 Idiopathic osteoporosis (Site unspecified)	0.003	0.997	0.000
M81.58 Idiopathic osteoporosis (Other)	0.003	0.997	0.000
M81.57 Idiopathic osteoporosis (Ankle and foot)	0.003	0.997	0.000
M81.56 Idiopathic osteoporosis (Lower leg)	0.003	0.997	0.000
M81.55 Idiopathic osteoporosis (Pelvic region and thigh)	0.003	0.997	0.000
M81.54 Idiopathic osteoporosis (Hand)	0.003	0.997	0.000
M81.53 Idiopathic osteoporosis (Forearm)	0.003	0.997	0.000
M81.52 Idiopathic osteoporosis (Upper arm)	0.003	0.997	0.000
M81.51 Idiopathic osteoporosis (Shoulder region)	0.003	0.997	0.000
M81.50 Idiopathic osteoporosis (Multiple sites)	0.003	0.997	0.000
M81.69 Localized osteoporosis [Lequesne] (Site unspecified)	0.003	0.997	0.000
M81.68 Localized osteoporosis [Lequesne] (Other)	0.003	0.997	0.000
M81.67 Localized osteoporosis [Lequesne] (Ankle and foot)	0.003	0.997	0.000
M81.66 Localized osteoporosis [Lequesne] (Lower leg)	0.003	0.997	0.000
M81.65 Localized osteoporosis [Lequesne] (Pelvic region and thigh)	0.003	0.997	0.000
M81.64 Localized osteoporosis [Lequesne] (Hand)	0.003	0.997	0.000
M81.63 Localized osteoporosis [Lequesne] (Forearm)	0.003	0.997	0.000
M81.62 Localized osteoporosis [Lequesne] (Upper arm)	0.003	0.997	0.000
M81.61 Localized osteoporosis [Lequesne] (Shoulder region)	0.003	0.997	0.000
M81.60 Localized osteoporosis [Lequesne] (Multiple sites)	0.003	0.997	0.000
M81.89 Other osteoporosis (Site unspecified)	0.003	0.997	0.000
M81.88 Other osteoporosis (Other)	0.003	0.997	0.000
M81.87 Other osteoporosis (Ankle and foot)	0.003	0.997	0.000
M81.86 Other osteoporosis (Lower leg)	0.003	0.997	0.000
M81.85 Other osteoporosis (Pelvic region and thigh)	0.003	0.997	0.000
M81.84 Other osteoporosis (Hand)	0.003	0.997	0.000
M81.83 Other osteoporosis (Forearm)	0.003	0.997	0.000
M81.82 Other osteoporosis (Upper arm)	0.003	0.997	0.000
M81.81 Other osteoporosis (Shoulder region)	0.003	0.997	0.000
M81.80 Other osteoporosis (Multiple sites)	0.003	0.997	0.000
D61 Other aplastic anaemias	0.000	0.997	0.003
M81.08 Postmenopausal osteoporosis (Other)	0.003	0.997	0.000
M81.07 Postmenopausal osteoporosis (Ankle and foot)	0.003	0.997	0.000
M81.06 Postmenopausal osteoporosis (Lower leg)	0.003	0.997	0.000
M81.05 Postmenopausal osteoporosis (Pelvic region and thigh)	0.003	0.997	0.000
M81.04 Postmenopausal osteoporosis (Hand)	0.003	0.997	0.000
M81.03 Postmenopausal osteoporosis (Forearm)	0.003	0.997	0.000
M81.02 Postmenopausal osteoporosis (Upper arm)	0.003	0.997	0.000
M81.01 Postmenopausal osteoporosis (Shoulder region)	0.003	0.997	0.000
M81.00 Postmenopausal osteoporosis (Multiple sites)	0.003	0.997	0.000
M81.39 Postsurgical malabsorption osteoporosis (Site unspecified)	0.003	0.997	0.000
M81.38 Postsurgical malabsorption osteoporosis (Other)	0.003	0.997	0.000
M81.37 Postsurgical malabsorption osteoporosis (Ankle and foot)	0.003	0.997	0.000
M81.36 Postsurgical malabsorption osteoporosis (Lower leg)	0.003	0.997	0.000
M81.35 Postsurgical malabsorption osteoporosis (Pelvic region and thigh)	0.003	0.997	0.000
M81.34 Postsurgical malabsorption osteoporosis (Hand)	0.003	0.997	0.000
M81.33 Postsurgical malabsorption osteoporosis (Forearm)	0.003	0.997	0.000
M81.32 Postsurgical malabsorption osteoporosis (Upper arm)	0.003	0.997	0.000
M81.31 Postsurgical malabsorption osteoporosis (Shoulder region)	0.003	0.997	0.000
M81.09 Postmenopausal osteoporosis (Site unspecified)	0.003	0.997	0.000
M81.30 Postsurgical malabsorption osteoporosis (Multiple sites)	0.003	0.997	0.000
H74.8 Other specified disorders of middle ear and mastoid	0.003	0.997	0.000
L43.9 Lichen planus, unspecified	0.000	0.997	0.003
M81.48 Drug-induced osteoporosis (Other)	0.003	0.997	0.000
M81.47 Drug-induced osteoporosis (Ankle and foot)	0.003	0.997	0.000
M81.46 Drug-induced osteoporosis (Lower leg)	0.003	0.997	0.000
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)	0.003	0.997	0.000
M81.44 Drug-induced osteoporosis (Hand)	0.003	0.997	0.000
M81.43 Drug-induced osteoporosis (Forearm)	0.003	0.997	0.000
M81.42 Drug-induced osteoporosis (Upper arm)	0.003	0.997	0.000
M81.41 Drug-induced osteoporosis (Shoulder region)	0.003	0.997	0.000
G62 Other polyneuropathies	0.003	0.997	0.000
E87.6 Hypokalaemia	0.003	0.997	0.000
N05.9 Unspecified	0.003	0.997	0.000
I98.2 Oesophageal varices in diseases classified elsewhere	0.003	0.997	0.000
I78.0 Hereditary haemorrhagic telangiectasia	0.003	0.997	0.000
N64.8 Other specified disorders of breast	0.003	0.997	0.000
H69.8 Other specified disorders of Eustachian tube	0.002	0.997	0.000
Z91.1 Personal history of noncompliance with medical treatment and regimen	0.000	0.997	0.003
D61.0 Constitutional aplastic anaemia	0.000	0.997	0.002
D61.1 Drug-induced aplastic anaemia	0.000	0.998	0.002
H65.2 Chronic serous otitis media	0.002	0.998	0.000
D61.8 Other specified aplastic anaemias	0.000	0.998	0.002
D61.3 Idiopathic aplastic anaemia	0.000	0.998	0.002
D61.2 Aplastic anaemia due to other external agents	0.000	0.998	0.002
S81.0 Open wound of knee	0.000	0.998	0.002
D33.3 Cranial nerves	0.002	0.998	0.000
H52.7 Disorder of refraction, unspecified	0.000	0.998	0.002
M85.6 Other cyst of bone	0.002	0.998	0.000
I78 Diseases of capillaries	0.002	0.998	0.000
M85.67 Other cyst of bone (Ankle and foot)	0.002	0.998	0.000
K57.8 Diverticular disease of intestine, part unspecified, with perforation and abscess	0.002	0.998	0.000
M85.65 Other cyst of bone (Pelvic region and thigh)	0.002	0.998	0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.002	0.998	0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances	0.002	0.998	0.000
G62.2 Polyneuropathy due to other toxic agents	0.002	0.998	0.000
K61.3 Ischiorectal abscess	0.002	0.998	0.000
G62.0 Drug-induced polyneuropathy	0.002	0.998	0.000
G62.1 Alcoholic polyneuropathy	0.002	0.998	0.000
H52.0 Hypermetropia	0.000	0.998	0.002
M85 Other disorders of bone density and structure	0.002	0.998	0.000
I78.9 Disease of capillaries, unspecified	0.002	0.998	0.000
N05 Unspecified nephritic syndrome	0.002	0.998	0.000
O36.0 Maternal care for rhesus isoimmunisation	0.002	0.998	0.000
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.000	0.998	0.002
H69.9 Eustachian tube disorder, unspecified	0.002	0.998	0.000
S02.50 Fracture of tooth (closed)	0.000	0.998	0.002
Z99.8 Dependence on other enabling machines and devices	0.000	0.998	0.002
M81.40 Drug-induced osteoporosis (Multiple sites)	0.002	0.998	0.000
N05.2 Diffuse membranous glomerulonephritis	0.002	0.998	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.000	0.998	0.002
Z94 Transplanted organ and tissue status	0.000	0.998	0.002
M85.8 Other specified disorders of bone density and structure	0.002	0.998	0.000
N05.3 Diffuse mesangial proliferative glomerulonephritis	0.002	0.998	0.000
M67.4 Ganglion	0.002	0.998	0.000
N05.5 Diffuse mesangiocapillary glomerulonephritis	0.002	0.998	0.000
S72.00 Fracture of neck of femur (closed)	0.000	0.998	0.002
R82.9 Other and unspecified abnormal finding in urine	0.002	0.998	0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.000	0.998	0.002
M80-M85 Disorders of bone density and structure	0.002	0.998	0.000
M85.69 Other cyst of bone (Site unspecified)	0.002	0.998	0.000
M85.68 Other cyst of bone (Other)	0.002	0.998	0.000
M85.66 Other cyst of bone (Lower leg)	0.002	0.998	0.000
M85.63 Other cyst of bone (Forearm)	0.002	0.998	0.000
M85.62 Other cyst of bone (Upper arm)	0.002	0.998	0.000
M85.61 Other cyst of bone (Shoulder region)	0.002	0.998	0.000
M85.60 Other cyst of bone (Multiple sites)	0.002	0.998	0.000
M85.88 Other specified disorders of bone density and structure (Other)	0.002	0.998	0.000
F06.7 Mild cognitive disorder	0.002	0.998	0.000
Z90.1 Acquired absence of breast(s)	0.002	0.998	0.000
M82.10 Osteoporosis in endocrine disorders (Multiple sites)	0.002	0.998	0.000
M85.86 Other specified disorders of bone density and structure (Lower leg)	0.002	0.998	0.000
C50.1 Central portion of breast	0.002	0.998	0.000
Z57.5 Occupational exposure to toxic agents in other industries	0.002	0.998	0.000
M82 Osteoporosis in diseases classified elsewhere	0.002	0.998	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.000	0.998	0.002
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)	0.002	0.998	0.000
M82.1 Osteoporosis in endocrine disorders	0.002	0.998	0.000
Z99.2 Dependence on renal dialysis	0.000	0.998	0.002
M67.47 Ganglion, ankle and foot	0.002	0.998	0.000
N05.8 Other	0.002	0.998	0.000
M85.64 Other cyst of bone (Hand)	0.002	0.998	0.000
H52.1 Myopia	0.000	0.998	0.002
N64.1 Fat necrosis of breast	0.002	0.998	0.000
X62.9 Unspecified place	0.002	0.998	0.000
B90-B94 Sequelae of infectious and parasitic diseases	0.002	0.998	0.000
S32.10 Fracture of sacrum (closed)	0.000	0.998	0.002
M85.5 Aneurysmal bone cyst	0.002	0.998	0.000
M85.4 Solitary bone cyst	0.002	0.998	0.000
M85.3 Osteitis condensans	0.002	0.998	0.000
M85.2 Hyperostosis of skull	0.002	0.998	0.000
M85.1 Skeletal fluorosis	0.002	0.998	0.000
M85.9 Disorder of bone density and structure, unspecified	0.002	0.998	0.000
N05.7 Diffuse crescentic glomerulonephritis	0.002	0.998	0.000
N05.6 Dense deposit disease	0.002	0.998	0.000
N05.4 Diffuse endocapillary proliferative glomerulonephritis	0.002	0.998	0.000
N05.0 Minor glomerular abnormality	0.002	0.998	0.000
H52 Disorders of refraction and accommodation	0.000	0.998	0.002
S27.0 Traumatic pneumothorax	0.000	0.998	0.002
H02.5 Other disorders affecting eyelid function	0.000	0.998	0.002
W18.3 Sports and athletics area	0.002	0.998	0.000
S32.40 Fracture of acetabulum (closed)	0.000	0.998	0.002
C45.0 Mesothelioma of pleura	0.002	0.998	0.000
S22 Fracture of rib(s), sternum and thoracic spine	0.000	0.998	0.002
S27.10 Traumatic haemothorax (without open wound into thoracic cavity)	0.000	0.998	0.002
Z94.1 Heart transplant status	0.000	0.998	0.002
I78.8 Other diseases of capillaries	0.002	0.998	0.000
Z94.9 Transplanted organ and tissue status, unspecified	0.000	0.998	0.002
Z94.6 Bone transplant status	0.000	0.998	0.002
Z94.5 Skin transplant status	0.000	0.998	0.002
Z94.3 Heart and lungs transplant status	0.000	0.998	0.002
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.002	0.998	0.000
M67.49 Ganglion, multiple sites	0.002	0.998	0.000
M67.45 Ganglion, hip	0.002	0.998	0.000
M85.87 Other specified disorders of bone density and structure (Ankle and foot)	0.002	0.998	0.000
M85.84 Other specified disorders of bone density and structure (Hand)	0.002	0.998	0.000
M85.83 Other specified disorders of bone density and structure (Forearm)	0.002	0.998	0.000
M85.82 Other specified disorders of bone density and structure (Upper arm)	0.002	0.998	0.000
M85.81 Other specified disorders of bone density and structure (Shoulder region)	0.002	0.998	0.000
N05.1 Focal and segmental glomerular lesions	0.002	0.998	0.000
N34.2 Other urethritis	0.002	0.998	0.000
Z99.9 Dependence on unspecified enabling machine and device	0.000	0.998	0.002
Z99.4 Dependence on artificial heart	0.000	0.998	0.002
Z99.0 Dependence on aspirator	0.000	0.998	0.002
M83 Adult osteomalacia	0.002	0.998	0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters	0.002	0.998	0.000
M85.0 Fibrous dysplasia (monostotic)	0.002	0.998	0.000
O26.9 Pregnancy-related condition, unspecified	0.002	0.998	0.000
T83.0 Mechanical complication of urinary (indwelling) catheter	0.002	0.998	0.000
V23.4 Driver injured in traffic accident	0.000	0.998	0.002
M11.26 Other chondrocalcinosis (Lower leg)	0.002	0.998	0.000
M82.8 Osteoporosis in other diseases classified elsewhere	0.001	0.998	0.000
M82.0 Osteoporosis in multiple myelomatosis	0.001	0.998	0.000
M82.3 Osteoporosis in diseases classified elsewhere, Forearm	0.001	0.998	0.000
Z94.2 Lung transplant status	0.000	0.998	0.002
M82.19 Osteoporosis in endocrine disorders (Site unspecified)	0.001	0.998	0.000
M82.18 Osteoporosis in endocrine disorders (Other)	0.001	0.998	0.000
M82.17 Osteoporosis in endocrine disorders (Ankle and foot)	0.001	0.998	0.000
M82.16 Osteoporosis in endocrine disorders (Lower leg)	0.001	0.998	0.000
M82.15 Osteoporosis in endocrine disorders (Pelvic region and thigh)	0.001	0.998	0.000
M82.14 Osteoporosis in endocrine disorders (Hand)	0.001	0.998	0.000
M82.13 Osteoporosis in endocrine disorders (Forearm)	0.001	0.998	0.000
M82.12 Osteoporosis in endocrine disorders (Upper arm)	0.001	0.998	0.000
S27.1 Traumatic haemothorax	0.000	0.998	0.002
G62.8 Other specified polyneuropathies	0.002	0.998	0.000
M82.11 Osteoporosis in endocrine disorders (Shoulder region)	0.002	0.998	0.000
N42.1 Congestion and haemorrhage of prostate	0.002	0.998	0.000
Z71.6 Tobacco abuse counselling	0.000	0.998	0.002
B90 Sequelae of tuberculosis	0.001	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations