TreeWAS – Variant ID: rs8176745

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities	0.000	0.000	1.000
I80 Phlebitis and thrombophlebitis	0.000	0.004	0.996
Z86.7 Personal history of diseases of the circulatory system	0.000	0.029	0.971
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.000	0.037	0.963
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.000	0.051	0.949
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.000	0.053	0.947
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.000	0.120	0.880
I80.8 Phlebitis and thrombophlebitis of other sites	0.000	0.143	0.857
I82 Other venous embolism and thrombosis	0.000	0.152	0.848
I82.8 Embolism and thrombosis of other specified veins	0.000	0.165	0.835
I85 Oesophageal varices	0.000	0.233	0.767
I86 Varicose veins of other sites	0.000	0.257	0.743
I87 Other disorders of veins	0.000	0.275	0.725
I81 Portal vein thrombosis	0.000	0.314	0.686
I85.9 Oesophageal varices without bleeding	0.000	0.332	0.668
I83 Varicose veins of lower extremities	0.000	0.348	0.652
I87.1 Compression of vein	0.000	0.358	0.642
I86.4 Gastric varices	0.000	0.369	0.631
I86.8 Varicose veins of other specified sites	0.000	0.387	0.613
I82.1 Thrombophlebitis migrans	0.000	0.392	0.608
I82.0 Budd-Chiari syndrome	0.000	0.392	0.608
I85.0 Oesophageal varices with bleeding	0.000	0.410	0.590
I88 Nonspecific lymphadenitis	0.000	0.414	0.586
I80.9 Phlebitis and thrombophlebitis of unspecified site	0.000	0.414	0.586
I82.3 Embolism and thrombosis of renal vein	0.000	0.418	0.582
I82.9 Embolism and thrombosis of unspecified vein	0.000	0.428	0.571
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.000	0.440	0.560
I82.2 Embolism and thrombosis of vena cava	0.000	0.459	0.541
I86.3 Vulval varices	0.000	0.467	0.533
I86.0 Sublingual varices	0.000	0.467	0.533
I83.9 Varicose veins of lower extremities without ulcer or inflammation	0.000	0.478	0.522
I83.2 Varicose veins of lower extremities with both ulcer and inflammation	0.000	0.479	0.521
I87.9 Disorder of vein, unspecified	0.000	0.480	0.520
I87.0 Postphlebitic syndrome	0.000	0.480	0.520
I86.2 Pelvic varices	0.000	0.487	0.513
I83.1 Varicose veins of lower extremities with inflammation	0.000	0.488	0.512
I87.2 Venous insufficiency (chronic) (peripheral)	0.000	0.503	0.497
I87.8 Other specified disorders of veins	0.000	0.521	0.479
I86.1 Scrotal varices	0.000	0.527	0.473
I26 Pulmonary embolism	0.000	0.568	0.432
I88.0 Nonspecific mesenteric lymphadenitis	0.000	0.575	0.425
I88.8 Other nonspecific lymphadenitis	0.000	0.579	0.420
I88.1 Chronic lymphadenitis, except mesenteric	0.000	0.579	0.420
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.000	0.617	0.383
I88.9 Nonspecific lymphadenitis, unspecified	0.000	0.629	0.370
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified	0.000	0.707	0.293
I89.1 Lymphangitis	0.000	0.760	0.240
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.000	0.776	0.223
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes	0.000	0.777	0.223
I83.0 Varicose veins of lower extremities with ulcer	0.000	0.778	0.221
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.000	0.785	0.215
I89.0 Lymphoedema, not elsewhere classified	0.000	0.837	0.163
Chapter IX Diseases of the circulatory system	0.000	0.843	0.157
I28 Other diseases of pulmonary vessels	0.000	0.857	0.143
Z86.1 Personal history of infectious and parasitic diseases	0.000	0.877	0.123
Z86 Personal history of certain other diseases	0.000	0.884	0.116
I00-I02 Acute rheumatic fever	0.000	0.887	0.113
I28.9 Disease of pulmonary vessels, unspecified	0.000	0.897	0.103
I28.1 Aneurysm of pulmonary artery	0.000	0.897	0.103
I28.0 Arteriovenous fistula of pulmonary vessels	0.000	0.897	0.103
I28.8 Other specified diseases of pulmonary vessels	0.000	0.908	0.092
I05-I09 Chronic rheumatic heart diseases	0.000	0.909	0.091
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.000	0.917	0.083
I02 Rheumatic chorea	0.000	0.919	0.081
I01 Rheumatic fever with heart involvement	0.000	0.919	0.081
I00 Rheumatic fever without mention of heart involvement	0.000	0.919	0.081
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)	0.000	0.920	0.080
I09 Other rheumatic heart diseases	0.000	0.925	0.075
I27 Other pulmonary heart diseases	0.000	0.925	0.075
I05 Rheumatic mitral valve diseases	0.000	0.928	0.072
I05.9 Mitral valve disease, unspecified	0.000	0.936	0.064
I09.9 Rheumatic heart disease, unspecified	0.000	0.936	0.063
I06 Rheumatic aortic valve diseases	0.000	0.938	0.062
M79.86 Other specified soft tissue disorders (Lower leg)	0.000	0.938	0.062
Z86.3 Personal history of endocrine, nutritional and metabolic diseases	0.000	0.941	0.059
I01.9 Acute rheumatic heart disease, unspecified	0.000	0.941	0.058
I01.8 Other acute rheumatic heart disease	0.000	0.941	0.058
I01.2 Acute rheumatic myocarditis	0.000	0.941	0.058
I01.1 Acute rheumatic endocarditis	0.000	0.941	0.058
I01.0 Acute rheumatic pericarditis	0.000	0.941	0.058
I02.9 Rheumatic chorea without heart involvement	0.000	0.941	0.058
I02.0 Rheumatic chorea with heart involvement	0.000	0.941	0.058
I27.8 Other specified pulmonary heart diseases	0.000	0.942	0.058
I05.0 Mitral stenosis	0.000	0.943	0.057
I09.8 Other specified rheumatic heart diseases	0.000	0.946	0.054
I09.2 Chronic rheumatic pericarditis	0.000	0.946	0.054
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.000	0.946	0.054
I09.0 Rheumatic myocarditis	0.000	0.946	0.054
I27.1 Kyphoscoliotic heart disease	0.000	0.946	0.054
I05.2 Mitral stenosis with insufficiency	0.000	0.949	0.051
I07 Rheumatic tricuspid valve diseases	0.000	0.954	0.046
I06.9 Rheumatic aortic valve disease, unspecified	0.000	0.955	0.045
I06.8 Other rheumatic aortic valve diseases	0.000	0.955	0.045
I06.2 Rheumatic aortic stenosis with insufficiency	0.000	0.955	0.045
I06.1 Rheumatic aortic insufficiency	0.000	0.955	0.045
I27.0 Primary pulmonary hypertension	0.000	0.957	0.043
M79.8 Other specified soft tissue disorders	0.000	0.957	0.043
I05.8 Other mitral valve diseases	0.000	0.958	0.042
I08 Multiple valve diseases	0.000	0.958	0.042
I06.0 Rheumatic aortic stenosis	0.000	0.958	0.041
Z92.1 Personal history of long-term (current) use of anticoagulants	0.000	0.960	0.040
I05.1 Rheumatic mitral insufficiency	0.000	0.960	0.040
M79.87 Other specified soft tissue disorders (Ankle and foot)	0.000	0.961	0.039
I08.2 Disorders of both aortic and tricuspid valves	0.000	0.962	0.038
I20-I25 Ischaemic heart diseases	0.000	0.964	0.036
M79.88 Other specified soft tissue disorders (Other)	0.000	0.966	0.034
I27.9 Pulmonary heart disease, unspecified	0.000	0.966	0.034
M79.82 Other specified soft tissue disorders (Upper arm)	0.000	0.966	0.034
I08.8 Other multiple valve diseases	0.000	0.966	0.034
I07.9 Tricuspid valve disease, unspecified	0.000	0.966	0.033
I07.8 Other tricuspid valve diseases	0.000	0.966	0.033
I07.2 Tricuspid stenosis with insufficiency	0.000	0.966	0.033
I07.0 Tricuspid stenosis	0.000	0.966	0.033
I95-I99 Other and unspecified disorders of the circulatory system	0.000	0.967	0.033
I10-I15 Hypertensive diseases	0.000	0.968	0.032
M79.84 Other specified soft tissue disorders (Hand)	0.000	0.968	0.032
I27.2 Other secondary pulmonary hypertension	0.000	0.969	0.031
M79.81 Other specified soft tissue disorders (Shoulder region)	0.000	0.969	0.031
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)	0.000	0.969	0.031
M79.80 Other specified soft tissue disorders (Multiple sites)	0.000	0.969	0.031
I22 Subsequent myocardial infarction	0.000	0.969	0.031
I08.9 Multiple valve disease, unspecified	0.000	0.971	0.029
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.000	0.971	0.029
M79.89 Other specified soft tissue disorders (Site unspecified)	0.000	0.972	0.028
I22.1 Subsequent myocardial infarction of inferior wall	0.000	0.972	0.028
I23 Certain current complications following acute myocardial infarction	0.000	0.973	0.027
H72.9 Perforation of tympanic membrane, unspecified	0.000	0.973	0.027
I24 Other acute ischaemic heart diseases	0.000	0.973	0.027
I22.8 Subsequent myocardial infarction of other sites	0.000	0.974	0.026
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.000	0.975	0.025
H72 Perforation of tympanic membrane	0.000	0.975	0.025
M79.83 Other specified soft tissue disorders (Forearm)	0.000	0.976	0.024
H72.8 Other perforations of tympanic membrane	0.000	0.976	0.024
I11 Hypertensive heart disease	0.000	0.976	0.024
I13 Hypertensive heart and renal disease	0.000	0.976	0.023
I24.8 Other forms of acute ischaemic heart disease	0.000	0.977	0.023
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.000	0.977	0.023
I15 Secondary hypertension	0.000	0.978	0.022
I24.1 Dressler's syndrome	0.000	0.978	0.022
I70-I79 Diseases of arteries, arterioles and capillaries	0.000	0.978	0.022
I23.8 Other current complications following acute myocardial infarction	0.000	0.979	0.021
I98 Other disorders of circulatory system in diseases classified elsewhere	0.000	0.979	0.021
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.000	0.980	0.020
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.000	0.980	0.020
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.000	0.980	0.020
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.000	0.980	0.020
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.000	0.980	0.020
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.000	0.980	0.020
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.000	0.980	0.020
I11.0 Hypertensive heart disease with (congestive) heart failure	0.000	0.980	0.020
I22.9 Subsequent myocardial infarction of unspecified site	0.000	0.980	0.020
H72.1 Attic perforation of tympanic membrane	0.000	0.980	0.019
Z86.5 Personal history of other mental and behavioural disorders	0.000	0.982	0.018
H72.0 Central perforation of tympanic membrane	0.000	0.982	0.018
I97.9 Postprocedural disorder of circulatory system, unspecified	0.000	0.982	0.018
I97.0 Postcardiotomy syndrome	0.000	0.982	0.018
I21 Acute myocardial infarction	0.000	0.982	0.018
I24.9 Acute ischaemic heart disease, unspecified	0.000	0.982	0.018
H72.2 Other marginal perforations of tympanic membrane	0.000	0.983	0.017
I78 Diseases of capillaries	0.000	0.983	0.017
I13.9 Hypertensive heart and renal disease, unspecified	0.000	0.983	0.017
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.000	0.983	0.017
I13.1 Hypertensive heart and renal disease with renal failure	0.000	0.983	0.017
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.000	0.983	0.017
I21.9 Acute myocardial infarction, unspecified	0.000	0.983	0.017
I74 Arterial embolism and thrombosis	0.000	0.983	0.017
I15.8 Other secondary hypertension	0.000	0.984	0.016
I15.2 Hypertension secondary to endocrine disorders	0.000	0.984	0.016
I15.0 Renovascular hypertension	0.000	0.984	0.016
I97.1 Other functional disturbances following cardiac surgery	0.000	0.984	0.016
I22.0 Subsequent myocardial infarction of anterior wall	0.000	0.984	0.016
I15.9 Seconday hypertension, unspecified	0.000	0.984	0.016
I15.1 Hypertension secondary to other renal disorders	0.000	0.984	0.016
I73 Other peripheral vascular diseases	0.000	0.985	0.015
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.000	0.985	0.015
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.000	0.985	0.015
I98.0 Cardiovascular syphilis	0.000	0.985	0.015
I98.2 Oesophageal varices in diseases classified elsewhere	0.000	0.985	0.015
I78.1 Naevus, nonneoplastic	0.000	0.985	0.015
H65.3 Chronic mucoid otitis media	0.000	0.985	0.015
H65-H75 Diseases of middle ear and mastoid	0.000	0.985	0.015
I21.2 Acute transmural myocardial infarction of other sites	0.000	0.986	0.014
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.986	0.014
H74 Other disorders of middle ear and mastoid	0.000	0.986	0.014
I07.1 Tricuspid insufficiency	0.000	0.986	0.014
O16 Unspecified maternal hypertension	0.014	0.986	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.000	0.986	0.014
I70 Atherosclerosis	0.000	0.986	0.013
I73.9 Peripheral vascular disease, unspecified	0.000	0.987	0.013
I21.X Presumed acute myicardial infaction (unconfirmed)	0.000	0.987	0.013
H65 Nonsuppurative otitis media	0.000	0.987	0.013
I11.9 Hypertensive heart disease without (congestive) heart failure	0.000	0.987	0.013
H74.0 Tympanosclerosis	0.000	0.987	0.013
I74.5 Embolism and thrombosis of iliac artery	0.000	0.987	0.013
I78.0 Hereditary haemorrhagic telangiectasia	0.000	0.987	0.013
H74.4 Polyp of middle ear	0.000	0.987	0.013
I21.0 Acute transmural myocardial infarction of anterior wall	0.000	0.987	0.013
I78.9 Disease of capillaries, unspecified	0.000	0.987	0.012
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.000	0.987	0.012
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.000	0.987	0.012
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.000	0.988	0.012
H74.1 Adhesive middle ear disease	0.000	0.988	0.012
I97.2 Postmastectomy lymphoedema syndrome	0.000	0.988	0.012
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.000	0.988	0.012
A04.7 Enterocolitis due to Clostridium difficile	0.012	0.988	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.000	0.988	0.012
I21.3 Acute transmural myocardial infarction of unspecified site	0.000	0.988	0.011
I65.2 Occlusion and stenosis of carotid artery	0.000	0.989	0.011
A04 Other bacterial intestinal infections	0.011	0.989	0.000
I74.9 Embolism and thrombosis of unspecified artery	0.000	0.989	0.011
I73.8 Other specified peripheral vascular diseases	0.000	0.989	0.011
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.000	0.989	0.011
I74.8 Embolism and thrombosis of other arteries	0.000	0.989	0.011
A04.5 Campylobacter enteritis	0.011	0.989	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.000	0.989	0.011
H70 Mastoiditis and related conditions	0.000	0.989	0.011
I78.8 Other diseases of capillaries	0.000	0.989	0.011
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.000	0.989	0.011
H68 Eustachian salpingitis and obstruction	0.000	0.989	0.011
H67 Otitis media in diseases classified elsewhere	0.000	0.989	0.011
I73.1 Thromboangiitis obliterans [Buerger]	0.000	0.989	0.011
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.989	0.010
I79.1 Aortitis in diseases classified elsewhere	0.000	0.989	0.010
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.000	0.989	0.010
H65.4 Other chronic nonsuppurative otitis media	0.000	0.990	0.010
H66 Suppurative and unspecified otitis media	0.000	0.990	0.010
I70.8 Atherosclerosis of other arteries	0.000	0.990	0.010
I70.1 Atherosclerosis of renal artery	0.000	0.990	0.010
H74.2 Discontinuity and dislocation of ear ossicles	0.000	0.990	0.010
A00-A09 Intestinal infectious diseases	0.010	0.990	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.000	0.990	0.010
I12 Hypertensive renal disease	0.000	0.990	0.010
Q38-Q45 Other congenital malformations of the digestive system	0.010	0.990	0.000
B17.1 Acute hepatitis C	0.010	0.990	0.000
E83.5 Disorders of calcium metabolism	0.010	0.990	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.000	0.990	0.009
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.000	0.990	0.010
I77 Other disorders of arteries and arterioles	0.000	0.991	0.009
A09 Diarrhoea and gastro-enteritis of presumed infectious origin	0.009	0.991	0.000
I99 Other and unspecified disorders of circulatory system	0.001	0.991	0.009
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.009	0.991	0.000
H71 Cholesteatoma of middle ear	0.000	0.991	0.009
A04.9 Bacterial intestinal infection, unspecified	0.009	0.991	0.000
I60-I69 Cerebrovascular diseases	0.000	0.991	0.009
H65.1 Other acute nonsuppurative otitis media	0.000	0.991	0.009
A04.4 Other intestinal Escherichia coli infections	0.009	0.991	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.000	0.991	0.009
I70.9 Generalised and unspecified atherosclerosis	0.000	0.991	0.009
I08.0 Disorders of both mitral and aortic valves	0.000	0.991	0.009
A09.9 Gastroenteritis and colitis of unspecified origin	0.009	0.991	0.000
I70.0 Atherosclerosis of aorta	0.000	0.991	0.009
H69 Other disorders of Eustachian tube	0.000	0.991	0.009
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.009	0.991	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.009	0.991	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.009	0.991	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.009	0.991	0.000
A04.6 Enteritis due to Yersinia enterocolitica	0.008	0.992	0.000
A04.3 Enterohaemorrhagic Escherichia coli infection	0.008	0.992	0.000
A04.2 Enteroinvasive Escherichia coli infection	0.008	0.992	0.000
A04.1 Enterotoxigenic Escherichia coli infection	0.008	0.992	0.000
A04.0 Enteropathogenic Escherichia coli infection	0.008	0.992	0.000
H65.0 Acute serous otitis media	0.000	0.992	0.008
H66.9 Otitis media, unspecified	0.000	0.992	0.008
H70.9 Mastoiditis, unspecified	0.000	0.992	0.008
H74.3 Other acquired abnormalities of ear ossicles	0.000	0.992	0.008
Q43 Other congenital malformations of intestine	0.008	0.992	0.000
Y85.0 Sequelae of motor-vehicle accident	0.000	0.992	0.008
I77.2 Rupture of artery	0.000	0.992	0.008
H65.2 Chronic serous otitis media	0.000	0.992	0.008
H70.8 Other mastoiditis and related conditions	0.000	0.992	0.008
H70.2 Petrositis	0.000	0.992	0.008
H70.0 Acute mastoiditis	0.000	0.992	0.008
Q45 Other congenital malformations of digestive system	0.008	0.992	0.000
H67.8 Otitis media in other diseases classified elsewhere	0.000	0.992	0.008
H67.1 Otitis media in viral diseases classified elsewhere	0.000	0.992	0.008
H67.0 Otitis media in bacterial diseases classified elsewhere	0.000	0.992	0.008
H68.1 Obstruction of Eustachian tube	0.000	0.992	0.008
H68.0 Eustachian salpingitis	0.000	0.992	0.008
H70.1 Chronic mastoiditis	0.000	0.992	0.008
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.000	0.992	0.008
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.000	0.992	0.008
H66.3 Other chronic suppurative otitis media	0.000	0.992	0.008
A02 Other Salmonella infections	0.008	0.992	0.000
Q50-Q56 Congenital malformations of genital organs	0.008	0.992	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.000	0.992	0.008
T78.3 Angioneurotic oedema	0.000	0.992	0.008
A09.0 Other and unspecified gastroenteritis and colitis of infectious origin	0.008	0.992	0.000
Q12 Congenital lens malformations	0.008	0.992	0.000
I70.80 Atherosclerosis of other arteries (without gangrene)	0.000	0.992	0.008
Q40 Other congenital malformations of upper alimentary tract	0.008	0.992	0.000
I70.10 Atherosclerosis of renal artery (without gangrene)	0.000	0.992	0.008
I72 Other aneurysm	0.000	0.992	0.008
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.008	0.992	0.000
A05 Other bacterial foodborne intoxications	0.008	0.992	0.000
I73.0 Raynaud's syndrome	0.000	0.992	0.008
Q76 Congenital malformations of spine and bony thorax	0.008	0.992	0.000
A08 Viral and other specified intestinal infections	0.008	0.992	0.000
I70.11 Atherosclerosis of renal artery (with gangrene)	0.000	0.992	0.007
I70.81 Atherosclerosis of other arteries (with gangrene)	0.000	0.992	0.007
I21.1 Acute transmural myocardial infarction of inferior wall	0.000	0.992	0.008
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.008	0.992	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.007	0.992	0.000
Q35-Q37 Cleft lip and cleft palate	0.007	0.992	0.000
E83.3 Disorders of phosphorus metabolism	0.007	0.993	0.000
I77.6 Arteritis, unspecified	0.000	0.993	0.007
Q38.5 Congenital malformations of palate, not elsewhere classified	0.007	0.993	0.000
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit	0.007	0.993	0.000
Q52 Other congenital malformations of female genitalia	0.007	0.993	0.000
Q38.1 Ankyloglossia	0.007	0.993	0.000
H66.4 Suppurative otitis media, unspecified	0.000	0.993	0.007
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.007	0.993	0.000
Q38.6 Other congenital malformations of mouth	0.007	0.993	0.000
Q43.9 Congenital malformation of intestine, unspecified	0.007	0.993	0.000
A06 Amoebiasis	0.007	0.993	0.000
A03 Shigellosis	0.007	0.993	0.000
A01 Typhoid and paratyphoid fevers	0.007	0.993	0.000
A00 Cholera	0.007	0.993	0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.000	0.993	0.007
T78.4 Allergy, unspecified	0.000	0.993	0.007
Q39 Congenital malformations of oesophagus	0.007	0.993	0.000
Q12.0 Congenital cataract	0.007	0.993	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.007	0.993	0.000
I77.0 Arteriovenous fistula, acquired	0.000	0.993	0.007
Q17 Other congenital malformations of ear	0.007	0.993	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.007	0.993	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.007	0.993	0.000
E83 Disorders of mineral metabolism	0.007	0.993	0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.000	0.993	0.007
I65.8 Occlusion and stenosis of other precerebral artery	0.000	0.993	0.007
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.007	0.993	0.000
I65.0 Occlusion and stenosis of vertebral artery	0.000	0.993	0.007
O14.0 Moderate preeclampsia	0.007	0.993	0.000
Q00-Q07 Congenital malformations of the nervous system	0.007	0.993	0.000
I77.5 Necrosis of artery	0.000	0.993	0.007
I77.4 Coeliac artery compression syndrome	0.000	0.993	0.007
I77.3 Arterial fibromuscular dysplasia	0.000	0.993	0.007
H66.1 Chronic tubotympanic suppurative otitis media	0.000	0.993	0.007
H66.0 Acute suppurative otitis media	0.000	0.993	0.007
H74.8 Other specified disorders of middle ear and mastoid	0.000	0.993	0.007
Q68 Other congenital musculoskeletal deformities	0.007	0.993	0.000
Q38.0 Congenital malformations of lips, not elsewhere classified	0.007	0.993	0.000
Q45.8 Other specified congenital malformations of digestive system	0.007	0.993	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.007	0.993	0.000
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.007	0.993	0.000
Q78 Other osteochondrodysplasias	0.007	0.993	0.000
H73 Other disorders of tympanic membrane	0.000	0.993	0.007
O12.0 Gestational oedema	0.007	0.993	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.000	0.993	0.007
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.007	0.993	0.000
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.000	0.993	0.006
Q60-Q64 Congenital malformations of the urinary system	0.007	0.993	0.000
Q43.0 Meckel's diverticulum	0.007	0.993	0.000
Q52.8 Other specified congenital malformations of female genitalia	0.007	0.993	0.000
Q51 Congenital malformations of uterus and cervix	0.007	0.993	0.000
B02.9 Zoster without complication	0.007	0.993	0.000
Q43.3 Congenital malformations of intestinal fixation	0.007	0.993	0.000
A07 Other protozoal intestinal diseases	0.007	0.993	0.000
I65.1 Occlusion and stenosis of basilar artery	0.000	0.993	0.006
O12.1 Gestational proteinuria	0.007	0.993	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.006	0.993	0.000
I70.01 Atherosclerosis of aorta (with gangrene)	0.000	0.993	0.006
H69.0 Patulous Eustachian tube	0.000	0.993	0.006
Q10.0 Congenital ptosis	0.006	0.993	0.000
Q16 Congenital malformations of ear causing impairment of hearing	0.006	0.993	0.000
Q15 Other congenital malformations of eye	0.006	0.993	0.000
Q13 Congenital malformations of anterior segment of eye	0.006	0.993	0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos	0.006	0.993	0.000
Q38.8 Other congenital malformations of pharynx	0.006	0.993	0.000
Q38.4 Congenital malformations of salivary glands and ducts	0.006	0.993	0.000
Q38.3 Other congenital malformations of tongue	0.006	0.993	0.000
Q38.2 Macroglossia	0.006	0.993	0.000
B17 Other acute viral hepatitis	0.006	0.993	0.000
T78 Adverse effects, not elsewhere classified	0.000	0.993	0.007
Q75 Other congenital malformations of skull and face bones	0.006	0.994	0.000
Q73 Reduction defects of unspecified limb	0.006	0.994	0.000
Q72 Reduction defects of lower limb	0.006	0.994	0.000
Q71 Reduction defects of upper limb	0.006	0.994	0.000
Q70 Syndactyly	0.006	0.994	0.000
Q69 Polydactyly	0.006	0.994	0.000
I77.8 Other specified disorders of arteries and arterioles	0.000	0.994	0.006
I68 Cerebrovascular disorders in diseases classified elsewhere	0.000	0.994	0.006
Q14 Congenital malformations of posterior segment of eye	0.006	0.994	0.000
I72.2 Aneurysm of renal artery	0.000	0.994	0.006
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.006	0.994	0.000
O15 Eclampsia	0.006	0.994	0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.006	0.994	0.000
A02.0 Salmonella gastro-enteritis	0.006	0.994	0.000
Q61 Cystic kidney disease	0.006	0.994	0.000
Y85 Sequelae of transport accidents	0.000	0.994	0.006
Q40.8 Other specified congenital malformations of upper alimentary tract	0.006	0.994	0.000
A05.9 Bacterial foodborne intoxication, unspecified	0.006	0.994	0.000
Q31 Congenital malformations of larynx	0.006	0.994	0.000
A02.9 Salmonella infection, unspecified	0.006	0.994	0.000
Q43.7 Persistent cloaca	0.006	0.994	0.000
Q43.6 Congenital fistula of rectum and anus	0.006	0.994	0.000
Q43.5 Ectopic anus	0.006	0.994	0.000
Q43.4 Duplication of intestine	0.006	0.994	0.000
Q43.2 Other congenital functional disorders of colon	0.006	0.994	0.000
Q43.1 Hirschsprung's disease	0.006	0.994	0.000
Q37 Cleft palate with cleft lip	0.006	0.994	0.000
D68.2 Hereditary deficiency of other clotting factors	0.000	0.994	0.006
I67.8 Other specified cerebrovascular diseases	0.000	0.994	0.006
I72.8 Aneurysm of other specified arteries	0.000	0.994	0.006
Q61.3 Polycystic kidney, unspecified	0.006	0.994	0.000
Q99 Other chromosome abnormalities, not elsewhere classified	0.006	0.994	0.000
A08.5 Other specified intestinal infections	0.006	0.994	0.000
A08.1 Acute gastro-enteropathy due to Norwalk agent	0.006	0.994	0.000
I67 Other cerebrovascular diseases	0.000	0.994	0.006
A08.4 Viral intestinal infection, unspecified	0.006	0.994	0.000
Q21 Congenital malformations of cardiac septa	0.006	0.994	0.000
Q17.5 Prominent ear	0.006	0.994	0.000
Q40.2 Other specified congenital malformations of stomach	0.006	0.994	0.000
H69.9 Eustachian tube disorder, unspecified	0.000	0.994	0.006
Q52.5 Fusion of labia	0.006	0.994	0.000
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.000	0.994	0.006
Q45.9 Congenital malformation of digestive system, unspecified	0.006	0.994	0.000
Q45.3 Other congenital malformations of pancreas and pancreatic duct	0.006	0.994	0.000
Q45.2 Congenital pancreatic cyst	0.006	0.994	0.000
Q45.1 Annular pancreas	0.006	0.994	0.000
Q45.0 Agenesis, aplasia and hypoplasia of pancreas	0.006	0.994	0.000
Q79.6 Ehlers-Danlos syndrome	0.006	0.994	0.000
Q51.3 Bicornate uterus	0.006	0.994	0.000
Q76.0 Spina bifida occulta	0.006	0.994	0.000
Q90 Down's syndrome	0.006	0.994	0.000
Q80-Q89 Other congenital malformations	0.006	0.994	0.000
A02.8 Other specified Salmonella infections	0.006	0.994	0.000
A02.2 Localised Salmonella infections	0.006	0.994	0.000
A02.1 Salmonella septicaemia	0.006	0.994	0.000
Q07 Other congenital malformations of nervous system	0.006	0.994	0.000
Q56 Indeterminate sex and pseudohermaphroditism	0.006	0.994	0.000
O14.1 Severe preeclampsia	0.006	0.994	0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.000	0.994	0.006
Q55 Other congenital malformations of male genital organs	0.006	0.994	0.000
Q12.9 Congenital lens malformation, unspecified	0.006	0.994	0.000
Q12.8 Other congenital lens malformations	0.006	0.994	0.000
Q12.4 Spherophakia	0.006	0.994	0.000
Q12.3 Congenital aphakia	0.006	0.994	0.000
Q12.2 Coloboma of lens	0.006	0.994	0.000
Q12.1 Congenital displaced lens	0.006	0.994	0.000
Q23 Congenital malformations of aortic and mitral valves	0.006	0.994	0.000
Q65 Congenital deformities of hip	0.006	0.994	0.000
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.000	0.994	0.005
Q18 Other congenital malformations of face and neck	0.006	0.994	0.000
Q40.9 Congenital malformation of upper alimentary tract, unspecified	0.006	0.994	0.000
Q40.3 Congenital malformation of stomach, unspecified	0.006	0.994	0.000
Q40.1 Congenital hiatus hernia	0.006	0.994	0.000
Q40.0 Congenital hypertrophic pyloric stenosis	0.006	0.994	0.000
I67.0 Dissection of cerebral arteries, nonruptured	0.000	0.994	0.006
I72.6 Aneurysm and dissection of vertebral artery	0.000	0.994	0.006
I72.5 Aneurysm and dissection of other precerebral arteries	0.000	0.994	0.006
I72.1 Aneurysm of artery of upper extremity	0.000	0.994	0.006
Q24 Other congenital malformations of heart	0.006	0.994	0.000
Q66 Congenital deformities of feet	0.006	0.994	0.000
Q68.8 Other specified congenital musculoskeletal deformities	0.006	0.994	0.000
Q76.1 Klippel-Feil syndrome	0.006	0.994	0.000
A05.8 Other specified bacterial foodborne intoxications	0.006	0.994	0.000
A05.4 Foodborne Bacillus cereus intoxication	0.006	0.994	0.000
A05.3 Foodborne Vibrio parahaemolyticus intoxication	0.006	0.994	0.000
A05.2 Foodborne Clostridium perfringens [Clostridium welchii] intoxication	0.006	0.994	0.000
A05.1 Botulism	0.006	0.994	0.000
A05.0 Foodborne staphylococcal intoxication	0.006	0.994	0.000
I72.9 Aneurysm of unspecified site	0.000	0.994	0.006
A08.2 Adenoviral enteritis	0.006	0.994	0.000
A08.0 Rotaviral enteritis	0.006	0.994	0.000
Q76.9 Congenital malformation of bony thorax, unspecified	0.006	0.994	0.000
Q76.8 Other congenital malformations of bony thorax	0.006	0.994	0.000
Q76.7 Congenital malformation of sternum	0.006	0.994	0.000
Q76.6 Other congenital malformations of ribs	0.006	0.994	0.000
Q76.5 Cervical rib	0.006	0.994	0.000
Q76.3 Congenital scoliosis due to congenital bony malformation	0.006	0.994	0.000
Q76.2 Congenital spondylolisthesis	0.006	0.994	0.000
Q39.4 Oesophageal web	0.006	0.994	0.000
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified	0.006	0.994	0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified	0.006	0.994	0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified	0.006	0.994	0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified	0.006	0.994	0.000
Q91 Edwards' syndrome and Patau's syndrome	0.006	0.994	0.000
Z97.8 Presence of other specified devices	0.000	0.994	0.006
Q34 Other congenital malformations of respiratory system	0.005	0.994	0.000
Q33 Congenital malformations of lung	0.005	0.994	0.000
Q32 Congenital malformations of trachea and bronchus	0.005	0.994	0.000
Q30 Congenital malformations of nose	0.005	0.994	0.000
Q78.0 Osteogenesis imperfecta	0.006	0.994	0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.000	0.994	0.005
O12.2 Gestational oedema with proteinuria	0.006	0.994	0.000
Q25 Congenital malformations of great arteries	0.006	0.994	0.000
Q36 Cleft lip	0.005	0.994	0.000
Q35 Cleft palate	0.005	0.994	0.000
Q96 Turner's syndrome	0.005	0.994	0.000
Q74 Other congenital malformations of limb(s)	0.005	0.994	0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.005	0.994	0.000
Q10.7 Congenital malformation of orbit	0.005	0.994	0.000
Q10.6 Other congenital malformations of lachrymal apparatus	0.005	0.994	0.000
Q10.5 Congenital stenosis and stricture of lachrymal duct	0.005	0.994	0.000
Q10.4 Absence and agenesis of lachrymal apparatus	0.005	0.994	0.000
Q10.3 Other congenital malformations of eyelid	0.005	0.994	0.000
Q10.2 Congenital entropion	0.005	0.994	0.000
Q10.1 Congenital ectropion	0.005	0.994	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.006	0.994	0.000
T90.2 Sequelae of fracture of skull and facial bones	0.000	0.994	0.006

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations