TreeWAS – Variant ID: rs817858

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
# Top node	1.000	0.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000	0.000
Chapter II Neoplasms	0.999	0.001	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.997	0.003	0.000
M80-M85 Disorders of bone density and structure	0.996	0.004	0.000
C43-C44 Melanoma and other malignant neoplasms of skin	0.994	0.006	0.000
S60-S69 Injuries to the wrist and hand	0.993	0.007	0.000
Chapter VI Diseases of the nervous system	0.989	0.011	0.000
M50-M54 Other dorsopathies	0.988	0.012	0.000
M81 Osteoporosis without pathological fracture	0.985	0.015	0.000
M81.9 Osteoporosis, unspecified	0.979	0.021	0.000
S61 Open wound of wrist and hand	0.978	0.022	0.000
S61.1 Open wound of finger(s) with damage to nail	0.969	0.031	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.968	0.032	0.000
C15-C26 Malignant neoplasms of digestive organs	0.967	0.033	0.000
C43 Malignant melanoma of skin	0.966	0.034	0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.966	0.034	0.000
C60-C63 Malignant neoplasms of male genital organs	0.965	0.035	0.000
M81.99 Osteoporosis, unspecified (Site unspecified)	0.965	0.035	0.000
M50 Cervical disk disorders	0.961	0.039	0.000
C44 Other malignant neoplasms of skin	0.960	0.040	0.000
G80-G83 Cerebral palsy and other paralytic syndromes	0.959	0.041	0.000
C18 Malignant neoplasm of colon	0.956	0.044	0.000
Chapter XIV Diseases of the genitourinary system	0.952	0.048	0.000
C43.7 Malignant melanoma of lower limb, including hip	0.951	0.049	0.000
C61 Malignant neoplasm of prostate	0.946	0.054	0.000
M05-M14 Inflammatory polyarthropathies	0.933	0.067	0.000
Chapter I Certain infectious and parasitic diseases	0.933	0.067	0.000
G40-G47 Episodic and paroxysmal disorders	0.925	0.075	0.000
N17-N19 Renal failure	0.923	0.077	0.000
C44.1 Skin of eyelid, including canthus	0.921	0.079	0.000
B95-B98 Bacterial, viral and other infectious agents	0.913	0.087	0.000
N18 Chronic renal failure	0.910	0.090	0.000
Chapter VIII Diseases of the ear and mastoid process	0.908	0.092	0.000
G81 Hemiplegia	0.906	0.094	0.000
T85 Complications of other internal prosthetic devices, implants and grafts	0.898	0.102	0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.892	0.108	0.000
G43 Migraine	0.892	0.108	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.891	0.109	0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.890	0.110	0.000
C18.2 Ascending colon	0.890	0.110	0.000
M10 Gout	0.890	0.110	0.000
N18.5 Chronic kidney disease, stage 5	0.885	0.115	0.000
H65-H75 Diseases of middle ear and mastoid	0.881	0.119	0.000
C18.9 Colon, unspecified	0.876	0.124	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.871	0.129	0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters	0.870	0.130	0.000
G81.9 Hemiplegia, unspecified	0.869	0.131	0.000
M85 Other disorders of bone density and structure	0.863	0.137	0.000
M10.9 Gout, unspecified	0.859	0.141	0.000
S40-S49 Injuries to the shoulder and upper arm	0.854	0.146	0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.850	0.150	0.000
C18.1 Appendix	0.850	0.150	0.000
S61.0 Open wound of finger(s) without damage to nail	0.850	0.150	0.000
S62 Fracture at wrist and hand level	0.849	0.151	0.000
M60-M63 Disorders of muscles	0.846	0.154	0.000
M53 Other dorsopathies, not elsewhere classified	0.846	0.154	0.000
N25-N29 Other disorders of kidney and ureter	0.846	0.154	0.000
M45-M49 Spondylopathies	0.846	0.154	0.000
C92 Myeloid leukaemia	0.843	0.157	0.000
M50.0 Cervical disk disorder with myelopathy	0.841	0.159	0.000
C91 Lymphoid leukaemia	0.838	0.162	0.000
H65 Nonsuppurative otitis media	0.838	0.162	0.000
M54 Dorsalgia	0.838	0.162	0.000
M07 Psoriatic and enteropathic arthropathies	0.837	0.163	0.000
M81.98 Osteoporosis, unspecified (Other)	0.836	0.164	0.000
M91-M94 Chondropathies	0.834	0.166	0.000
G43.9 Migraine, unspecified	0.834	0.166	0.000
N00-N08 Glomerular diseases	0.831	0.169	0.000
M84 Disorders of continuity of bone	0.830	0.170	0.000
M86-M90 Other osteopathies	0.829	0.171	0.000
N40-N51 Diseases of male genital organs	0.827	0.173	0.000
C19 Malignant neoplasm of rectosigmoid junction	0.824	0.175	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.824	0.176	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.821	0.179	0.000
C44.2 Skin of ear and external auricular canal	0.821	0.179	0.000
M10.99 Gout, unspecified (Site unspecified)	0.820	0.180	0.000
Chapter XXII Codes for special purposes	0.819	0.181	0.000
N18.0 End-stage renal disease	0.817	0.183	0.000
C44.0 Skin of lip	0.816	0.184	0.000
H65.3 Chronic mucoid otitis media	0.812	0.188	0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.811	0.189	0.000
M50.1 Cervical disk disorder with radiculopathy	0.810	0.190	0.000
S67 Crushing injury of wrist and hand	0.807	0.193	0.000
M50.9 Cervical disk disorder, unspecified	0.801	0.199	0.000
C81 Hodgkin's disease	0.800	0.200	0.000
G80 Infantile cerebral palsy	0.796	0.203	0.000
M81.90 Osteoporosis, unspecified (Multiple sites)	0.795	0.205	0.000
M47 Spondylosis	0.792	0.208	0.000
G62 Other polyneuropathies	0.787	0.213	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.784	0.216	0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.784	0.216	0.000
M50.3 Other cervical disk degeneration	0.783	0.217	0.000
N41 Inflammatory diseases of prostate	0.776	0.224	0.000
N99-N99 Other disorders of the genitourinary system	0.775	0.225	0.000
C64-C68 Malignant neoplasms of urinary tract	0.775	0.225	0.000
M65-M68 Disorders of synovium and tendon	0.774	0.226	0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified	0.772	0.228	0.000
C18.7 Sigmoid colon	0.772	0.228	0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.772	0.228	0.000
C43.4 Malignant melanoma of scalp and neck	0.771	0.229	0.000
S60 Superficial injury of wrist and hand	0.771	0.229	0.000
M07.3 Other psoriatic arthropathies	0.767	0.233	0.000
C44.7 Skin of lower limb, including hip	0.766	0.234	0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters	0.765	0.235	0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.763	0.236	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.763	0.237	0.000
N10-N16 Renal tubulo-interstitial diseases	0.762	0.238	0.000
T84.0 Mechanical complication of internal joint prosthesis	0.762	0.238	0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters	0.762	0.238	0.000
M85.8 Other specified disorders of bone density and structure	0.761	0.239	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.756	0.244	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.756	0.244	0.000
M54.3 Sciatica	0.755	0.245	0.000
G82 Paraplegia and tetraplegia	0.753	0.247	0.000
M80 Osteoporosis with pathological fracture	0.752	0.248	0.000
C44.9 Malignant neoplasm of skin, unspecified	0.751	0.248	0.000
M50.2 Other cervical disk displacement	0.751	0.249	0.000
S10-S19 Injuries to the neck	0.746	0.254	0.000
C43.5 Malignant melanoma of trunk	0.746	0.254	0.000
C21 Malignant neoplasm of anus and anal canal	0.746	0.254	0.000
M53.3 Sacrococcygeal disorders, not elsewhere classified	0.744	0.256	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.743	0.257	0.000
C18.0 Caecum	0.743	0.257	0.000
G70-G73 Diseases of myoneural junction and muscle	0.740	0.260	0.000
G90-G99 Other disorders of the nervous system	0.739	0.260	0.000
S68 Traumatic amputation of wrist and hand	0.738	0.262	0.000
A30-A49 Other bacterial diseases	0.737	0.263	0.000
M54.2 Cervicalgia	0.737	0.263	0.000
M62 Other disorders of muscle	0.737	0.263	0.000
G43.1 Migraine with aura [classical migraine]	0.735	0.265	0.000
S61.7 Multiple open wounds of wrist and hand	0.734	0.266	0.000
M14 Arthropathies in other diseases classified elsewhere	0.733	0.267	0.000
H71 Cholesteatoma of middle ear	0.733	0.267	0.000
S70-S79 Injuries to the hip and thigh	0.730	0.270	0.000
N26 Unspecified contracted kidney	0.730	0.270	0.000
N70-N77 Inflammatory diseases of female pelvic organs	0.730	0.270	0.000
C83.0 Small cell (diffuse)	0.730	0.270	0.000
T85.4 Mechanical complication of breast prosthesis and implant	0.730	0.270	0.000
S62.6 Fracture of other finger	0.729	0.271	0.000
S49 Other and unspecified injuries of shoulder and upper arm	0.729	0.271	0.000
M00-M03 Infectious arthropathies	0.728	0.272	0.000
M82 Osteoporosis in diseases classified elsewhere	0.726	0.274	0.000
C91.1 Chronic lymphocytic leukaemia	0.726	0.274	0.000
G60 Hereditary and idiopathic neuropathy	0.726	0.274	0.000
G43.8 Other migraine	0.725	0.274	0.000
L20-L30 Dermatitis and eczema	0.725	0.275	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.725	0.275	0.000
G41 Status epilepticus	0.721	0.279	0.000
B90-B94 Sequelae of infectious and parasitic diseases	0.721	0.279	0.000
C26 Malignant neoplasm of other and ill-defined digestive organs	0.721	0.279	0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters	0.721	0.279	0.000
H74 Other disorders of middle ear and mastoid	0.720	0.280	0.000
M89 Other disorders of bone	0.719	0.281	0.000
Chapter V Mental and behavioural disorders	0.719	0.281	0.000
M10.96 Gout, unspecified (Lower leg)	0.719	0.281	0.000
G20-G26 Extrapyramidal and movement disorders	0.718	0.282	0.000
C92.1 Chronic myeloid leukaemia	0.718	0.282	0.000
C44.3 Skin of other and unspecified parts of face	0.718	0.282	0.000
G83 Other paralytic syndromes	0.718	0.282	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.718	0.282	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
T80 Complications following infusion, transfusion and therapeutic injection	0.716	0.283	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.716	0.284	0.000
C40-C41 Malignant neoplasms of bone and articular cartilage	0.716	0.284	0.000
T33-T35 Frostbite	0.715	0.285	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.715	0.285	0.000
T00-T07 Injuries involving multiple body regions	0.715	0.285	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.714	0.286	0.000
M83 Adult osteomalacia	0.714	0.286	0.000
S69 Other and unspecified injuries of wrist and hand	0.712	0.288	0.000
S65 Injury of blood vessels at wrist and hand level	0.712	0.288	0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.711	0.288	0.000
M54.1 Radiculopathy	0.708	0.292	0.000
C83.1 Small cleaved cell (diffuse)	0.707	0.293	0.000
L40-L45 Papulosquamous disorders	0.707	0.293	0.000
M81.8 Other osteoporosis	0.706	0.293	0.000
M81.6 Localised osteoporosis [Lequesne]	0.706	0.293	0.000
M81.5 Idiopathic osteoporosis	0.706	0.293	0.000
M81.3 Postsurgical malabsorption osteoporosis	0.706	0.293	0.000
M81.2 Osteoporosis of disuse	0.706	0.293	0.000
M81.1 Postoophorectomy osteoporosis	0.706	0.293	0.000
M81.0 Postmenopausal osteoporosis	0.706	0.293	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.705	0.295	0.000
G45 Transient cerebral ischaemic attacks and related syndromes	0.704	0.296	0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.702	0.298	0.000
M81.96 Osteoporosis, unspecified (Lower leg)	0.702	0.298	0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.702	0.298	0.000
M81.94 Osteoporosis, unspecified (Hand)	0.702	0.298	0.000
M81.93 Osteoporosis, unspecified (Forearm)	0.702	0.298	0.000
M81.92 Osteoporosis, unspecified (Upper arm)	0.702	0.298	0.000
M81.91 Osteoporosis, unspecified (Shoulder region)	0.702	0.298	0.000
C67 Malignant neoplasm of bladder	0.702	0.298	0.000
C18.6 Descending colon	0.702	0.298	0.000
G62.9 Polyneuropathy, unspecified	0.701	0.299	0.000
T84.1 Mechanical complication of internal fixation device of bones of limb	0.701	0.299	0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system	0.699	0.301	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.697	0.303	0.000
M54.39 Sciatica (Site unspecified)	0.696	0.304	0.000
Q60-Q64 Congenital malformations of the urinary system	0.696	0.304	0.000
N18.4 Chronic kidney disease, stage 4	0.695	0.305	0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.695	0.305	0.000
N41.1 Chronic prostatitis	0.695	0.305	0.000
S90-S99 Injuries to the ankle and foot	0.694	0.306	0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.694	0.306	0.000
A50-A64 Infections with a predominantly sexual mode of transmission	0.694	0.306	0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.694	0.306	0.000
C95 Leukaemia of unspecified cell type	0.694	0.306	0.000
C94 Other leukaemias of specified cell type	0.694	0.306	0.000
C93 Monocytic leukaemia	0.694	0.306	0.000
C88 Malignant immunoproliferative diseases	0.694	0.306	0.000
C86 Other specified types of T/NK-cell lymphoma	0.694	0.306	0.000
C84 Peripheral and cutaneous T-cell lymphomas	0.694	0.306	0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.693	0.307	0.000
C17 Malignant neoplasm of small intestine	0.693	0.307	0.000
C23 Malignant neoplasm of gallbladder	0.693	0.307	0.000
C43.8 Overlapping malignant melanoma of skin	0.693	0.307	0.000
C43.2 Malignant melanoma of ear and external auricular canal	0.693	0.307	0.000
C43.1 Malignant melanoma of eyelid, including canthus	0.693	0.307	0.000
C43.0 Malignant melanoma of lip	0.693	0.307	0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.692	0.307	0.000
C63 Malignant neoplasm of other and unspecified male genital organs	0.692	0.308	0.000
C60 Malignant neoplasm of penis	0.692	0.308	0.000
T87 Complications peculiar to reattachment and amputation	0.690	0.310	0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.689	0.311	0.000
M50.8 Other cervical disk disorders	0.689	0.311	0.000
N28 Other disorders of kidney and ureter, not elsewhere classified	0.689	0.311	0.000
C44.8 Overlapping lesion of skin	0.688	0.311	0.000
C43.9 Malignant melanoma of skin, unspecified	0.688	0.311	0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.688	0.312	0.000
C83.3 Large cell (diffuse)	0.688	0.312	0.000
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.687	0.312	0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.687	0.313	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.687	0.313	0.000
M93 Other osteochondropathies	0.686	0.314	0.000
T79-T79 Certain early complications of trauma	0.685	0.315	0.000
C18.8 Overlapping lesion of colon	0.685	0.315	0.000
L80-L99 Other disorders of the skin and subcutaneous tissue	0.685	0.315	0.000
M84.0 Malunion of fracture	0.685	0.315	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.683	0.317	0.000
L27 Dermatitis due to substances taken internally	0.682	0.318	0.000
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)	0.682	0.318	0.000
H73 Other disorders of tympanic membrane	0.681	0.319	0.000
M47.8 Other spondylosis	0.681	0.319	0.000
G80.9 Infantile cerebral palsy, unspecified	0.680	0.320	0.000
C81.9 Hodgkin's disease, unspecified	0.679	0.321	0.000
H90-H95 Other disorders of ear	0.678	0.322	0.000
S67.0 Crushing injury of thumb and other finger(s)	0.674	0.325	0.000
S42 Fracture of shoulder and upper arm	0.674	0.326	0.000
M05 Seropositive rheumatoid arthritis	0.674	0.326	0.000
M51 Other intervertebral disk disorders	0.674	0.326	0.000
N41.9 Inflammatory disease of prostate, unspecified	0.673	0.327	0.000
S62.7 Multiple fractures of fingers	0.673	0.327	0.000
B99-B99 Other infectious diseases	0.672	0.328	0.000
C92.0 Acute myeloid leukaemia	0.672	0.328	0.000
M53.38 Sacrococcygeal disorders, not elsewhere classified-Sacral/s	0.671	0.329	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.671	0.329	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.670	0.330	0.000
N02 Recurrent and persistent haematuria	0.670	0.330	0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters	0.669	0.331	0.000
M12 Other specific arthropathies	0.669	0.331	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.669	0.331	0.000
M08 Juvenile arthritis	0.669	0.331	0.000
B85-B89 Pediculosis, acariasis and other infestations	0.669	0.331	0.000
B65-B83 Helminthiases	0.669	0.331	0.000
B50-B64 Protozoal diseases	0.669	0.331	0.000
B20-B24 Human immunodeficiency virus [HIV] disease	0.669	0.331	0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.669	0.331	0.000
A75-A79 Rickettsioses	0.669	0.331	0.000
A70-A74 Other diseases caused by chlamydiae	0.669	0.331	0.000
A65-A69 Other spirochaetal diseases	0.669	0.331	0.000
A20-A28 Certain zoonotic bacterial diseases	0.669	0.331	0.000
A15-A19 Tuberculosis	0.669	0.331	0.000
T82.4 Mechanical complication of vascular dialysis catheter	0.668	0.332	0.000
N50 Other disorders of male genital organs	0.668	0.332	0.000
G63 Polyneuropathy in diseases classified elsewhere	0.666	0.334	0.000
N05 Unspecified nephritic syndrome	0.665	0.335	0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.664	0.336	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.663	0.336	0.000
G46 Vascular syndromes of brain in cerebrovascular diseases	0.663	0.337	0.000
A80-A89 Viral infections of the central nervous system	0.663	0.337	0.000
M81.4 Drug-induced osteoporosis	0.662	0.338	0.000
T82.3 Mechanical complication of other vascular grafts	0.662	0.338	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.661	0.339	0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.660	0.340	0.000
M45 Ankylosing spondylitis	0.660	0.340	0.000
B15-B19 Viral hepatitis	0.658	0.342	0.000
M62.8 Other specified disorders of muscle	0.658	0.342	0.000
N13 Obstructive and reflux uropathy	0.658	0.342	0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts	0.658	0.342	0.000
S62.60 Fracture of other finger (closed)	0.657	0.343	0.000
M40-M43 Deforming dorsopathies	0.657	0.343	0.000
M47.9 Spondylosis, unspecified	0.656	0.344	0.000
S32 Fracture of lumbar spine and pelvis	0.653	0.347	0.000
N18.8 Other chronic renal failure	0.652	0.348	0.000
N18.1 Chronic kidney disease, stage 1	0.652	0.348	0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.652	0.348	0.000
A49 Bacterial infection of unspecified site	0.652	0.348	0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.650	0.350	0.000
G81.1 Spastic hemiplegia	0.650	0.350	0.000
G81.0 Flaccid hemiplegia	0.650	0.350	0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified	0.649	0.351	0.000
N45 Orchitis and epididymitis	0.647	0.353	0.000
C18.3 Hepatic flexure	0.647	0.353	0.000
N03 Chronic nephritic syndrome	0.647	0.353	0.000
M94 Other disorders of cartilage	0.646	0.354	0.000
M47.2 Other spondylosis with radiculopathy	0.644	0.356	0.000
N76 Other inflammation of vagina and vulva	0.644	0.356	0.000
M54.22 Cervicalgia (Cervical region)	0.644	0.356	0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft	0.644	0.356	0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt	0.644	0.356	0.000
G99 Other disorders of nervous system in diseases classified elsewhere	0.644	0.356	0.000
C91.4 Hairy-cell leukaemia	0.642	0.358	0.000
H69 Other disorders of Eustachian tube	0.642	0.358	0.000
N18.3 Chronic kidney disease, stage 3	0.641	0.359	0.000
N19 Unspecified renal failure	0.640	0.360	0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.640	0.360	0.000
G43.3 Complicated migraine	0.640	0.360	0.000
G43.2 Status migrainosus	0.640	0.360	0.000
G43.0 Migraine without aura [common migraine]	0.640	0.360	0.000
S49.9 Unspecified injury of shoulder and upper arm	0.639	0.361	0.000
G64 Other disorders of peripheral nervous system	0.639	0.361	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.639	0.361	0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters	0.638	0.362	0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters	0.638	0.362	0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters	0.638	0.362	0.000
M10.4 Other secondary gout	0.638	0.362	0.000
M10.3 Gout due to impairment of renal function	0.638	0.362	0.000
M10.2 Drug-induced gout	0.638	0.362	0.000
M10.1 Lead-induced gout	0.638	0.362	0.000
M10.0 Idiopathic gout	0.638	0.362	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.637	0.363	0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified	0.637	0.363	0.000
B25-B34 Other viral diseases	0.636	0.364	0.000
Q80-Q89 Other congenital malformations	0.635	0.365	0.000
S62.3 Fracture of other metacarpal bone	0.635	0.365	0.000
T81 Complications of procedures, not elsewhere classified	0.634	0.366	0.000
T84.2 Mechanical complication of internal fixation device of other bones	0.634	0.366	0.000
L27.0 Generalised skin eruption due to drugs and medicaments	0.634	0.366	0.000
L40 Psoriasis	0.634	0.366	0.000
S64 Injury of nerves at wrist and hand level	0.633	0.367	0.000
M85.0 Fibrous dysplasia (monostotic)	0.633	0.367	0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.633	0.367	0.000
N28.8 Other specified disorders of kidney and ureter	0.632	0.368	0.000
T84.3 Mechanical complication of other bone devices, implants and grafts	0.632	0.368	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.632	0.368	0.000
H70 Mastoiditis and related conditions	0.632	0.368	0.000
H68 Eustachian salpingitis and obstruction	0.632	0.368	0.000
H67 Otitis media in diseases classified elsewhere	0.632	0.368	0.000
T85.2 Mechanical complication of intraocular lens	0.632	0.368	0.000
L90 Atrophic disorders of skin	0.630	0.370	0.000
M11 Other crystal arthropathies	0.629	0.371	0.000
N18.9 Chronic renal failure, unspecified	0.628	0.372	0.000
G47 Sleep disorders	0.628	0.372	0.000
D50-D53 Nutritional anaemias	0.627	0.373	0.000
G82.5 Tetraplegia, unspecified	0.627	0.373	0.000
F30-F39 Mood [affective] disorders	0.625	0.375	0.000
C16 Malignant neoplasm of stomach	0.625	0.375	0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.624	0.376	0.000
C83.7 Burkitt's tumour	0.624	0.376	0.000
C83.6 Undifferentiated (diffuse)	0.624	0.376	0.000
C83.5 Lymphoblastic (diffuse)	0.624	0.376	0.000
C83.4 Immunoblastic (diffuse)	0.624	0.376	0.000
C83.2 Mixed small and large cell (diffuse)	0.624	0.376	0.000
C62 Malignant neoplasm of testis	0.623	0.377	0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.622	0.378	0.000
S80-S89 Injuries to the knee and lower leg	0.621	0.378	0.001
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.621	0.379	0.000
C44.5 Skin of trunk	0.621	0.379	0.000
T86 Failure and rejection of transplanted organs and tissues	0.620	0.379	0.000
N18.2 Chronic kidney disease, stage 2	0.620	0.380	0.000
H74.0 Tympanosclerosis	0.619	0.381	0.000
M85.9 Disorder of bone density and structure, unspecified	0.618	0.381	0.000
M85.6 Other cyst of bone	0.618	0.381	0.000
M85.5 Aneurysmal bone cyst	0.618	0.381	0.000
M85.4 Solitary bone cyst	0.618	0.381	0.000
M85.3 Osteitis condensans	0.618	0.381	0.000
M85.2 Hyperostosis of skull	0.618	0.381	0.000
M85.1 Skeletal fluorosis	0.618	0.381	0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.617	0.383	0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified	0.617	0.383	0.000
H66 Suppurative and unspecified otitis media	0.616	0.383	0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.616	0.384	0.000
M90 Osteopathies in diseases classified elsewhere	0.616	0.384	0.000
M10.97 Gout, unspecified (Ankle and foot)	0.616	0.384	0.000
M89.9 Disorder of bone, unspecified	0.616	0.384	0.000
M70-M79 Other soft tissue disorders	0.616	0.384	0.000
M10.98 Gout, unspecified (Other)	0.616	0.384	0.000
M10.95 Gout, unspecified (Pelvic region and thigh)	0.616	0.384	0.000
M10.94 Gout, unspecified (Hand)	0.616	0.384	0.000
M10.93 Gout, unspecified (Forearm)	0.616	0.384	0.000
M10.92 Gout, unspecified (Upper arm)	0.616	0.384	0.000
M10.91 Gout, unspecified (Shoulder region)	0.616	0.384	0.000
M10.90 Gout, unspecified (Multiple sites)	0.616	0.384	0.000
S48 Traumatic amputation of shoulder and upper arm	0.613	0.387	0.000
S45 Injury of blood vessels at shoulder and upper arm level	0.613	0.387	0.000
S44 Injury of nerves at shoulder and upper arm level	0.613	0.387	0.000
S41 Open wound of shoulder and upper arm	0.613	0.387	0.000
S47 Crushing injury of shoulder and upper arm	0.613	0.387	0.000
T66-T78 Other and unspecified effects of external causes	0.611	0.389	0.000
S50-S59 Injuries to the elbow and forearm	0.610	0.390	0.000
S60.2 Contusion of other parts of wrist and hand	0.610	0.390	0.000
D51 Vitamin B12 deficiency anaemia	0.610	0.390	0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.610	0.390	0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.610	0.390	0.000
T82.0 Mechanical complication of heart valve prosthesis	0.610	0.390	0.000
S46 Injury of muscle and tendon at shoulder and upper arm level	0.610	0.390	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.609	0.391	0.000
T13 Other injuries of lower limb, level unspecified	0.609	0.391	0.000
S62.4 Multiple fractures of metacarpal bones	0.609	0.391	0.000
S62.1 Fracture of other carpal bone(s)	0.609	0.391	0.000
L90.5 Scar conditions and fibrosis of skin	0.609	0.391	0.000
Q50-Q56 Congenital malformations of genital organs	0.607	0.392	0.000
G30-G32 Other degenerative diseases of the nervous system	0.607	0.393	0.000
M63 Disorders of muscle in diseases classified elsewhere	0.607	0.393	0.000
M61 Calcification and ossification of muscle	0.607	0.393	0.000
M60 Myositis	0.607	0.393	0.000
G45.4 Transient global amnesia	0.607	0.393	0.000
M53.9 Dorsopathy, unspecified	0.607	0.393	0.000
M53.8 Other specified dorsopathies	0.607	0.393	0.000
M53.2 Spinal instabilities	0.607	0.393	0.000
M53.1 Cervicobrachial syndrome	0.607	0.393	0.000
M53.0 Cervicocranial syndrome	0.607	0.393	0.000
N29 Other disorders of kidney and ureter in diseases classified elsewhere	0.606	0.393	0.000
N27 Small kidney of unknown cause	0.606	0.393	0.000
N25 Disorders resulting from impaired renal tubular function	0.606	0.393	0.000
M49 Spondylopathies in diseases classified elsewhere	0.606	0.394	0.000
L89 Decubitus ulcer	0.606	0.394	0.000
C92.9 Myeloid leukaemia, unspecified	0.604	0.395	0.000
C92.8 Acute myeloid leukaemia with multilineage dysplasia	0.604	0.395	0.000
C92.7 Other myeloid leukaemia	0.604	0.395	0.000
C92.6 Acute myeloid leukaemia with 11q23-abnormality	0.604	0.395	0.000
C92.5 Acute myelomonocytic leukaemia	0.604	0.395	0.000
C92.4 Acute promyelocytic leukaemia	0.604	0.395	0.000
C92.3 Myeloid sarcoma	0.604	0.395	0.000
C92.2 Subacute myeloid leukaemia	0.604	0.395	0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified	0.603	0.396	0.000
N04 Nephrotic syndrome	0.603	0.397	0.000
G44 Other headache syndromes	0.602	0.398	0.000
Q61 Cystic kidney disease	0.602	0.398	0.000
S62.2 Fracture of first metacarpal bone	0.601	0.399	0.000
C91.9 Lymphoid leukaemia, unspecified	0.601	0.399	0.000
C91.8 Mature B-cell leukaemia Burkitt-type	0.601	0.399	0.000
C91.7 Other lymphoid leukaemia	0.601	0.399	0.000
C91.6 Prolymphocytic leukaemia of T-cell type	0.601	0.399	0.000
C91.5 Adult T-cell leukaemia	0.601	0.399	0.000
C91.3 Prolymphocytic leukaemia	0.601	0.399	0.000
C91.2 Subacute lymphocytic leukaemia	0.601	0.399	0.000
C91.0 Acute lymphoblastic leukaemia	0.601	0.399	0.000
G61 Inflammatory polyneuropathy	0.601	0.399	0.000
H65.2 Chronic serous otitis media	0.601	0.399	0.000
H65.1 Other acute nonsuppurative otitis media	0.601	0.399	0.000
H65.0 Acute serous otitis media	0.601	0.399	0.000
M54.8 Other dorsalgia	0.601	0.399	0.000
M54.6 Pain in thoracic spine	0.601	0.399	0.000
M54.0 Panniculitis affecting regions of neck and back	0.601	0.399	0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters	0.600	0.400	0.000
M07.6 Other enteropathic arthropathies	0.600	0.400	0.000
M07.5 Arthropathy in ulcerative colitis	0.600	0.400	0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.600	0.400	0.000
M07.2 Psoriatic spondylitis	0.600	0.400	0.000
M07.1 Arthritis mutilans	0.600	0.400	0.000
M07.0 Distal interphalangeal psoriatic arthropathy	0.600	0.400	0.000
M47.1 Other spondylosis with myelopathy	0.600	0.400	0.000
M54.16 Radiculopathy (Lumbar region)	0.599	0.400	0.000
G60.8 Other hereditary and idiopathic neuropathies	0.598	0.401	0.000
T88 Other complications of surgical and medical care, not elsewhere classified	0.598	0.401	0.000
M92 Other juvenile osteochondrosis	0.598	0.402	0.000
M91 Juvenile osteochondrosis of hip and pelvis	0.598	0.402	0.000
S62.0 Fracture of navicular [scaphoid] bone of hand	0.598	0.402	0.000
N08 Glomerular disorders in diseases classified elsewhere	0.598	0.402	0.000
S62.5 Fracture of thumb	0.597	0.403	0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters	0.597	0.403	0.000
N07 Hereditary nephropathy, not elsewhere classified	0.596	0.404	0.000
N06 Isolated proteinuria with specified morphological lesion	0.596	0.404	0.000
N01 Rapidly progressive nephritic syndrome	0.596	0.404	0.000
N00 Acute nephritic syndrome	0.596	0.404	0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.596	0.404	0.000
M84.9 Disorder of continuity of bone, unspecified	0.595	0.404	0.000
M84.8 Other disorders of continuity of bone	0.595	0.404	0.000
M84.4 Pathological fracture, not elsewhere classified	0.595	0.404	0.000
M84.3 Stress fracture, not elsewhere classified	0.595	0.404	0.000
M84.2 Delayed union of fracture	0.595	0.404	0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx	0.595	0.404	0.000
G62.8 Other specified polyneuropathies	0.595	0.405	0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters	0.594	0.406	0.000
C18.5 Splenic flexure	0.594	0.406	0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.594	0.406	0.000
N51 Disorders of male genital organs in diseases classified elsewhere	0.593	0.407	0.000
N46 Male infertility	0.593	0.407	0.000
N44 Torsion of testis	0.593	0.407	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.593	0.407	0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.592	0.408	0.000
C43.6 Malignant melanoma of upper limb, including shoulder	0.591	0.409	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.591	0.409	0.000
Q35-Q37 Cleft lip and cleft palate	0.591	0.409	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.591	0.409	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.591	0.409	0.000
Q00-Q07 Congenital malformations of the nervous system	0.591	0.409	0.000
M14.6 Neuropathic arthropathy	0.590	0.410	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations