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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs8192585
log Bayes Factor = 18.7691
Chromosome 6   position 32,188,823  (GRCh37) Explore rs8192585 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.9 Rheumatoid arthritis, unspecified
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
E10.3 With ophthalmic complications
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.999 0.001 0.000
M06 Other rheumatoid arthritis
0.999 0.001 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.999 0.001 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.999 0.001 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.999 0.001 0.000
Chapter V Mental and behavioural disorders
0.998 0.002 0.000
M05-M14 Inflammatory polyarthropathies
0.998 0.002 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.997 0.003 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.996 0.004 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.995 0.005 0.000
F30-F39 Mood [affective] disorders
0.988 0.012 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.979 0.021 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.977 0.023 0.000
E10.1 With ketoacidosis
0.973 0.027 0.000
Chapter VII Diseases of the eye and adnexa
0.973 0.027 0.000
E11 Non-insulin-dependent diabetes mellitus
0.970 0.030 0.000
E10.4 With neurological complications
0.963 0.037 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.961 0.039 0.000
H30-H36 Disorders of choroid and retina
0.961 0.039 0.000
H36.0 Diabetic retinopathy
0.961 0.039 0.000
H36 Retinal disorders in diseases classified elsewhere
0.961 0.039 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.960 0.040 0.000
F33 Recurrent depressive disorder
0.955 0.045 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.950 0.050 0.000
T43.2 Other and unspecified antidepressants
0.950 0.050 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.944 0.056 0.000
Chapter I Certain infectious and parasitic diseases
0.943 0.057 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.942 0.058 0.000
E10.5 With peripheral circulatory complications
0.938 0.062 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.923 0.077 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.917 0.083 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.913 0.087 0.000
L05 Pilonidal cyst
0.906 0.094 0.000
F33.9 Recurrent depressive disorder, unspecified
0.906 0.094 0.000
K90.0 Coeliac disease
0.000 0.098 0.902
H53-H54 Visual disturbances and blindness
0.899 0.101 0.000
E10.2 With renal complications
0.890 0.110 0.000
E14 Unspecified diabetes mellitus
0.885 0.115 0.000
E11.4 With neurological complications
0.876 0.123 0.000
H54 Blindness and low vision
0.875 0.125 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.874 0.126 0.000
B95-B98 Bacterial, viral and other infectious agents
0.870 0.130 0.000
F03 Unspecified dementia
0.868 0.132 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.863 0.137 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.860 0.140 0.000
A30-A49 Other bacterial diseases
0.857 0.143 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.852 0.148 0.000
M05 Seropositive rheumatoid arthritis
0.846 0.154 0.000
E11.5 With peripheral circulatory complications
0.843 0.157 0.000
H55-H59 Other disorders of eye and adnexa
0.842 0.158 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.833 0.167 0.000
M06.4 Inflammatory polyarthropathy
0.833 0.167 0.000
F31 Bipolar affective disorder
0.833 0.167 0.000
E10.0 With coma
0.830 0.170 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.828 0.172 0.000
S60-S69 Injuries to the wrist and hand
0.828 0.172 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.827 0.173 0.000
L05.9 Pilonidal cyst without abscess
0.827 0.173 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.825 0.175 0.000
M86-M90 Other osteopathies
0.824 0.176 0.000
H54.7 Unspecified visual loss
0.822 0.178 0.000
T66-T78 Other and unspecified effects of external causes
0.821 0.178 0.000
E11.6 With other specified complications
0.821 0.179 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.819 0.181 0.000
F34 Persistent mood [affective] disorders
0.819 0.181 0.000
L05.0 Pilonidal cyst with abscess
0.818 0.182 0.000
L40-L45 Papulosquamous disorders
0.818 0.182 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.814 0.186 0.000
S62 Fracture at wrist and hand level
0.809 0.191 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.809 0.191 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.807 0.193 0.000
M06.3 Rheumatoid nodule
0.806 0.194 0.000
H54.0 Blindness, both eyes
0.806 0.194 0.000
A49 Bacterial infection of unspecified site
0.804 0.196 0.000
M07 Psoriatic and enteropathic arthropathies
0.803 0.197 0.000
E40-E46 Malnutrition
0.802 0.197 0.000
M14 Arthropathies in other diseases classified elsewhere
0.802 0.198 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.802 0.198 0.000
S62.6 Fracture of other finger
0.801 0.199 0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms
0.801 0.199 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.800 0.200 0.000
E10.8 With unspecified complications
0.799 0.201 0.000
S62.60 Fracture of other finger (closed)
0.797 0.203 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.796 0.204 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.795 0.205 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.794 0.206 0.000
L03 Cellulitis
0.794 0.206 0.000
Chapter XX External causes of morbidity and mortality
0.792 0.208 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.790 0.210 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.789 0.211 0.000
E11.3 With ophthalmic complications
0.789 0.211 0.000
E10.6 With other specified complications
0.788 0.211 0.000
Chapter X Diseases of the respiratory system
0.783 0.217 0.000
F60-F69 Disorders of adult personality and behaviour
0.782 0.218 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.781 0.219 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.780 0.220 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.779 0.221 0.000
F39 Unspecified mood [affective] disorder
0.775 0.225 0.000
Chapter VIII Diseases of the ear and mastoid process
0.766 0.234 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.762 0.238 0.000
M65-M68 Disorders of synovium and tendon
0.762 0.238 0.000
M60-M63 Disorders of muscles
0.761 0.239 0.000
B15-B19 Viral hepatitis
0.759 0.241 0.000
F43 Reaction to severe stress, and adjustment disorders
0.759 0.241 0.000
S10-S19 Injuries to the neck
0.754 0.246 0.000
F32 Depressive episode
0.753 0.247 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.752 0.248 0.000
E14.3 With ophthalmic complications
0.748 0.252 0.000
E11.0 With coma
0.746 0.253 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.744 0.256 0.000
E14.8 With unspecified complications
0.744 0.256 0.000
A49.0 Staphylococcal infection, unspecified
0.744 0.256 0.000
M00-M03 Infectious arthropathies
0.743 0.257 0.000
E11.1 With ketoacidosis
0.742 0.258 0.000
A80-A89 Viral infections of the central nervous system
0.742 0.258 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.737 0.263 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.736 0.264 0.000
T42.0 Hydantoin derivatives
0.736 0.264 0.000
F80-F89 Disorders of psychological development
0.732 0.268 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.730 0.270 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.729 0.271 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.726 0.274 0.000
H31 Other disorders of choroid
0.725 0.275 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.720 0.280 0.000
F01 Vascular dementia
0.720 0.280 0.000
E13 Other specified diabetes mellitus
0.719 0.281 0.000
T42.1 Iminostilbenes
0.718 0.282 0.000
L03.8 Cellulitis of other sites
0.718 0.282 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.717 0.283 0.000
E10.7 With multiple complications
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
M91-M94 Chondropathies
0.716 0.284 0.000
M06.8 Other specified rheumatoid arthritis
0.716 0.284 0.000
M06.2 Rheumatoid bursitis
0.716 0.284 0.000
M06.1 Adult-onset Still's disease
0.716 0.284 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.716 0.284 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.716 0.284 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.716 0.284 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.716 0.284 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.716 0.284 0.000
T36 Poisoning by systemic antibiotics
0.716 0.284 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.716 0.284 0.000
F70-F79 Mental retardation
0.716 0.284 0.000
H43-H45 Disorders of vitreous body and globe
0.716 0.284 0.000
M12 Other specific arthropathies
0.715 0.285 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.715 0.285 0.000
M08 Juvenile arthritis
0.715 0.285 0.000
T33-T35 Frostbite
0.715 0.285 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.715 0.285 0.000
T00-T07 Injuries involving multiple body regions
0.715 0.285 0.000
H57 Other disorders of eye and adnexa
0.715 0.285 0.000
T43.9 Psychotropic drug, unspecified
0.714 0.286 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.714 0.286 0.000
T43.6 Psychostimulants with abuse potential
0.714 0.286 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.714 0.286 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.714 0.286 0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.714 0.286 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.713 0.287 0.000
M86 Osteomyelitis
0.713 0.287 0.000
M11 Other crystal arthropathies
0.713 0.287 0.000
L02.1 Cutaneous abscess, furuncle and carbuncle of neck
0.711 0.288 0.000
J09-J18 Influenza and pneumonia
0.711 0.289 0.000
M40-M43 Deforming dorsopathies
0.708 0.292 0.000
F38 Other mood [affective] disorders
0.708 0.292 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.704 0.296 0.000
H34 Retinal vascular occlusions
0.704 0.296 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.701 0.299 0.000
T50.8 Diagnostic agents
0.700 0.299 0.000
T50.7 Analeptics and opioid receptor antagonists
0.700 0.299 0.000
T50.6 Antidotes and chelating agents, not elsewhere classified
0.700 0.299 0.000
T50.5 Appetite depressants
0.700 0.299 0.000
T50.4 Drugs affecting uric acid metabolism
0.700 0.299 0.000
T50.3 Electrolytic, caloric and water-balance agents
0.700 0.299 0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.700 0.299 0.000
T50.1 Loop [high-ceiling] diuretics
0.700 0.299 0.000
T50.0 Mineralocorticoids and their antagonists
0.700 0.299 0.000
F30 Manic episode
0.699 0.301 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.698 0.302 0.000
F34.1 Dysthymia
0.697 0.302 0.000
L90 Atrophic disorders of skin
0.697 0.303 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.696 0.304 0.000
E11.8 With unspecified complications
0.695 0.304 0.000
E11.7 With multiple complications
0.695 0.304 0.000
H10-H13 Disorders of conjunctiva
0.693 0.307 0.000
F33.1 Recurrent depressive disorder, current episode moderate
0.692 0.308 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.692 0.308 0.000
L08 Other local infections of skin and subcutaneous tissue
0.692 0.308 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.691 0.309 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.690 0.310 0.000
S40-S49 Injuries to the shoulder and upper arm
0.690 0.310 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.689 0.311 0.000
H30 Chorioretinal inflammation
0.689 0.311 0.000
Q50-Q56 Congenital malformations of genital organs
0.689 0.311 0.000
A31 Infection due to other mycobacteria
0.689 0.311 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.689 0.311 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.689 0.311 0.000
L10-L14 Bullous disorders
0.688 0.311 0.000
Q38.7 Pharyngeal pouch
0.688 0.312 0.000
T68 Hypothermia
0.687 0.313 0.000
A49.8 Other bacterial infections of unspecified site
0.687 0.313 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.686 0.313 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.685 0.315 0.000
F33.8 Other recurrent depressive disorders
0.685 0.315 0.000
F33.4 Recurrent depressive disorder, currently in remission
0.685 0.315 0.000
F33.0 Recurrent depressive disorder, current episode mild
0.685 0.315 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.684 0.316 0.000
Chapter XXII Codes for special purposes
0.683 0.317 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.683 0.317 0.000
T42.4 Benzodiazepines
0.682 0.318 0.000
X60-X84 Intentional self-harm
0.680 0.320 0.000
F02 Dementia in other diseases classified elsewhere
0.679 0.321 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.679 0.321 0.000
T51 Toxic effect of alcohol
0.678 0.322 0.000
L04 Acute lymphadenitis
0.677 0.323 0.000
L01 Impetigo
0.677 0.323 0.000
L00 Staphylococcal scalded skin syndrome
0.677 0.323 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.676 0.324 0.000
B50-B64 Protozoal diseases
0.676 0.324 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.676 0.324 0.000
A75-A79 Rickettsioses
0.676 0.324 0.000
A70-A74 Other diseases caused by chlamydiae
0.676 0.324 0.000
A65-A69 Other spirochaetal diseases
0.676 0.324 0.000
A20-A28 Certain zoonotic bacterial diseases
0.676 0.324 0.000
A15-A19 Tuberculosis
0.676 0.324 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.676 0.324 0.000
H54.9 Unspecified visual impairment (binocular)
0.676 0.324 0.000
F99-F99 Unspecified mental disorder
0.675 0.325 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.674 0.325 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.673 0.327 0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.673 0.327 0.000
L91 Hypertrophic disorders of skin
0.672 0.328 0.000
B99-B99 Other infectious diseases
0.671 0.329 0.000
F29 Unspecified nonorganic psychosis
0.671 0.329 0.000
F41 Other anxiety disorders
0.669 0.331 0.000
M06.34 Rheumatoid nodule (Hand)
0.667 0.333 0.000
M10 Gout
0.666 0.334 0.000
M07.3 Other psoriatic arthropathies
0.664 0.336 0.000
M14.6 Neuropathic arthropathy
0.662 0.338 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.662 0.338 0.000
E46 Unspecified protein-energy malnutrition
0.662 0.338 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.661 0.339 0.000
F22 Persistent delusional disorders
0.661 0.339 0.000
M13 Other arthritis
0.660 0.340 0.000
S50-S59 Injuries to the elbow and forearm
0.659 0.341 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.658 0.342 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.657 0.343 0.000
F09 Unspecified organic or symptomatic mental disorder
0.657 0.343 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.657 0.343 0.000
L43 Lichen planus
0.657 0.343 0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified
0.656 0.344 0.000
M06.0 Seronegative rheumatoid arthritis
0.655 0.345 0.000
O48 Prolonged pregnancy
0.655 0.345 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.655 0.345 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.655 0.345 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.655 0.345 0.000
T42.3 Barbiturates
0.655 0.345 0.000
T42.2 Succinimides and oxazolidinediones
0.655 0.345 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.653 0.347 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.653 0.347 0.000
T79-T79 Certain early complications of trauma
0.653 0.347 0.000
T23 Burn and corrosion of wrist and hand
0.652 0.348 0.000
H65-H75 Diseases of middle ear and mastoid
0.650 0.350 0.000
E16 Other disorders of pancreatic internal secretion
0.649 0.351 0.000
M89 Other disorders of bone
0.647 0.352 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.647 0.353 0.000
B25-B34 Other viral diseases
0.643 0.356 0.000
O85-O92 Complications predominantly related to the puerperium
0.643 0.357 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.641 0.359 0.000
L42 Pityriasis rosea
0.640 0.360 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.638 0.362 0.000
F43.1 Posttraumatic stress disorder
0.637 0.363 0.000
F20 Schizophrenia
0.637 0.363 0.000
E14.7 With multiple complications
0.635 0.365 0.000
E14.6 With other specified complications
0.635 0.365 0.000
E14.5 With peripheral circulatory complications
0.635 0.365 0.000
E14.4 With neurological complications
0.635 0.365 0.000
E14.2 Withrenal complications
0.635 0.365 0.000
E14.1 With ketoacidosis
0.635 0.365 0.000
E14.0 With coma
0.635 0.365 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.634 0.366 0.000
B65-B83 Helminthiases
0.633 0.367 0.000
F00 Dementia in Alzheimer's disease
0.632 0.368 0.000
T63 Toxic effect of contact with venomous animals
0.632 0.368 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.632 0.368 0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.630 0.370 0.000
A40 Streptococcal septicaemia
0.629 0.370 0.000
H54.6 Unqualified visual loss, one eye
0.627 0.372 0.000
H54.5 Low vision, one eye
0.627 0.372 0.000
H54.3 Unqualified visual loss, both eyes
0.627 0.372 0.000
H54.2 Low vision, both eyes
0.627 0.372 0.000
H54.1 Blindness, one eye, low vision, other eye
0.627 0.372 0.000
L40 Psoriasis
0.627 0.373 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.627 0.373 0.000
Q35-Q37 Cleft lip and cleft palate
0.627 0.373 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.627 0.373 0.000
F60 Specific personality disorders
0.627 0.373 0.000
T20 Burn and corrosion of head and neck
0.627 0.373 0.000
L03.3 Cellulitis of trunk
0.626 0.374 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.626 0.374 0.000
O80-O84 Delivery
0.626 0.374 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.624 0.376 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.622 0.378 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.622 0.378 0.000
F43.2 Adjustment disorders
0.622 0.378 0.000
T45.0 Antiallergic and antiemetic drugs
0.621 0.379 0.000
S64 Injury of nerves at wrist and hand level
0.621 0.379 0.000
V10-V19 Pedal cyclist injured in transport accident
0.619 0.381 0.000
E14.9 Without complications
0.618 0.382 0.000
A00-A09 Intestinal infectious diseases
0.618 0.382 0.000
H55 Nystagmus and other irregular eye movements
0.617 0.383 0.000
J00-J06 Acute upper respiratory infections
0.616 0.384 0.000
O47 False labour
0.616 0.384 0.000
A48 Other bacterial diseases, not elsewhere classified
0.615 0.385 0.000
A44 Bartonellosis
0.615 0.385 0.000
A43 Nocardiosis
0.615 0.385 0.000
A42 Actinomycosis
0.615 0.385 0.000
A39 Meningococcal infection
0.615 0.385 0.000
A37 Whooping cough
0.615 0.385 0.000
A36 Diphtheria
0.615 0.385 0.000
A32 Listeriosis
0.615 0.385 0.000
A30 Leprosy [Hansen's disease]
0.615 0.385 0.000
A38 Scarlet fever
0.615 0.385 0.000
A35 Other tetanus
0.615 0.385 0.000
A34 Obstetrical tetanus
0.615 0.385 0.000
A33 Tetanus neonatorum
0.615 0.385 0.000
E11.2 With renal complications
0.614 0.386 0.000
S70-S79 Injuries to the hip and thigh
0.613 0.386 0.000
S90-S99 Injuries to the ankle and foot
0.613 0.387 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.613 0.387 0.000
L03.0 Cellulitis of finger and toe
0.612 0.388 0.000
F48 Other neurotic disorders
0.611 0.389 0.000
F44 Dissociative [conversion] disorders
0.611 0.389 0.000
Y00-Y09 Assault
0.610 0.390 0.000
M67 Other disorders of synovium and tendon
0.610 0.390 0.000
O30 Multiple gestation
0.610 0.390 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.609 0.391 0.000
F45 Somatoform disorders
0.609 0.391 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.608 0.392 0.000
M05.8 Other seropositive rheumatoid arthritis
0.606 0.394 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.606 0.394 0.000
M05.2 Rheumatoid vasculitis
0.606 0.394 0.000
M05.1 Rheumatoid lung disease
0.606 0.394 0.000
M05.0 Felty's syndrome
0.606 0.394 0.000
B00 Herpesviral [herpes simplex] infections
0.604 0.396 0.000
B18 Chronic viral hepatitis
0.604 0.396 0.000
M86.9 Osteomyelitis, unspecified
0.604 0.396 0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere
0.604 0.396 0.000
T78 Adverse effects, not elsewhere classified
0.603 0.397 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.603 0.397 0.000
Q80-Q89 Other congenital malformations
0.603 0.397 0.000
E20-E35 Disorders of other endocrine glands
0.602 0.398 0.000
T39.1 4-Aminophenol derivatives
0.602 0.398 0.000
H43 Disorders of vitreous body
0.601 0.399 0.000
A87 Viral meningitis
0.599 0.401 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.597 0.402 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.597 0.403 0.000
M06.48 Inflammatory polyarthropathy (Other)
0.597 0.403 0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.597 0.403 0.000
M06.46 Inflammatory polyarthropathy (Lower leg)
0.597 0.403 0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.597 0.403 0.000
M06.44 Inflammatory polyarthropathy (Hand)
0.597 0.403 0.000
M06.43 Inflammatory polyarthropathy (Forearm)
0.597 0.403 0.000
M06.42 Inflammatory polyarthropathy (Upper arm)
0.597 0.403 0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.597 0.403 0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.597 0.403 0.000
F31.8 Other bipolar affective disorders
0.597 0.403 0.000
F31.7 Bipolar affective disorder, currently in remission
0.597 0.403 0.000
F31.6 Bipolar affective disorder, current episode mixed
0.597 0.403 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.597 0.403 0.000
S62.5 Fracture of thumb
0.597 0.403 0.000
T59 Toxic effect of other gases, fumes and vapours
0.596 0.404 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.595 0.405 0.000
L84 Corns and callosities
0.594 0.406 0.000
F28 Other nonorganic psychotic disorders
0.594 0.406 0.000
F24 Induced delusional disorder
0.594 0.406 0.000
F21 Schizotypal disorder
0.594 0.406 0.000
S65 Injury of blood vessels at wrist and hand level
0.593 0.406 0.000
M62 Other disorders of muscle
0.593 0.406 0.000
T65 Toxic effect of other and unspecified substances
0.593 0.407 0.000
T62 Toxic effect of other noxious substances eaten as food
0.593 0.407 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.593 0.407 0.000
T60 Toxic effect of pesticides
0.593 0.407 0.000
T57 Toxic effect of other inorganic substances
0.593 0.407 0.000
T56 Toxic effect of metals
0.593 0.407 0.000
T54 Toxic effect of corrosive substances
0.593 0.407 0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone
0.593 0.407 0.000
T52 Toxic effect of organic solvents
0.593 0.407 0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants
0.593 0.407 0.000
T58 Toxic effect of carbon monoxide
0.593 0.407 0.000
T55 Toxic effect of soaps and detergents
0.593 0.407 0.000
Y52 Agents primarily affecting the cardiovascular system
0.593 0.407 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.593 0.407 0.000
A41 Other septicaemia
0.592 0.408 0.000
O32.8 Maternal care for other malpresentation of foetus
0.592 0.408 0.000
X20-X29 Contact with venomous animals and plants
0.590 0.410 0.000
F31.9 Bipolar affective disorder, unspecified
0.589 0.410 0.000
T75 Effects of other external causes
0.589 0.411 0.000
T74 Maltreatment syndromes
0.589 0.411 0.000
T73 Effects of other deprivation
0.589 0.411 0.000
T70 Effects of air pressure and water pressure
0.589 0.411 0.000
T69 Other effects of reduced temperature
0.589 0.411 0.000
T67 Effects of heat and light
0.589 0.411 0.000
T71 Asphyxiation
0.589 0.411 0.000
T66 Unspecified effects of radiation
0.589 0.411 0.000
S62.2 Fracture of first metacarpal bone
0.589 0.411 0.000
H57.1 Ocular pain
0.589 0.411 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.589 0.411 0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system
0.587 0.413 0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified
0.587 0.413 0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified
0.587 0.413 0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.587 0.413 0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.587 0.413 0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.587 0.413 0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified
0.587 0.413 0.000
T44.1 Other parasympathomimetics [cholinergics]
0.587 0.413 0.000
T44.0 Anticholinesterase agents
0.587 0.413 0.000
F34.9 Persistent mood [affective] disorder, unspecified
0.587 0.413 0.000
F34.8 Other persistent mood [affective] disorders
0.587 0.413 0.000
F34.0 Cyclothymia
0.587 0.413 0.000
L44 Other papulosquamous disorders
0.586 0.413 0.000
L41 Parapsoriasis
0.586 0.413 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.586 0.413 0.000
S62.61 Fracture of other finger (open)
0.586 0.414 0.000
L03.2 Cellulitis of face
0.586 0.414 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.585 0.414 0.000
F32.1 Moderate depressive episode
0.585 0.415 0.000
Q00-Q07 Congenital malformations of the nervous system
0.585 0.415 0.000
S12 Fracture of neck
0.585 0.415 0.000
E50-E64 Other nutritional deficiencies
0.585 0.415 0.000
L90.0 Lichen sclerosus et atrophicus
0.584 0.416 0.000
T25 Burn and corrosion of ankle and foot
0.583 0.416 0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot
0.583 0.416 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.583 0.416 0.000
T21 Burn and corrosion of trunk
0.583 0.416 0.000
L90.5 Scar conditions and fibrosis of skin
0.583 0.417 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.582 0.418 0.000
O44 Placenta praevia
0.580 0.420 0.000
M13.0 Polyarthritis, unspecified
0.580 0.420 0.000
S62.7 Multiple fractures of fingers
0.580 0.420 0.000
S62.4 Multiple fractures of metacarpal bones
0.580 0.420 0.000
S62.1 Fracture of other carpal bone(s)
0.580 0.420 0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system
0.580 0.420 0.000
T46.8 Antivaricose drugs, including sclerosing agents
0.580 0.420 0.000
T46.7 Peripheral vasodilators
0.580 0.420 0.000
T46.5 Other antihypertensive drugs, not elsewhere classified
0.580 0.420 0.000
T46.3 Coronary vasodilators, not elsewhere classified
0.580 0.420 0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified
0.580 0.420 0.000
T46.1 Calcium-channel blockers
0.580 0.420 0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action
0.580 0.420 0.000
F42 Obsessive-compulsive disorder
0.579 0.421 0.000
F41.1 Generalised anxiety disorder
0.579 0.421 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.579 0.421 0.000
F01.9 Vascular dementia, unspecified
0.579 0.421 0.000
D50-D53 Nutritional anaemias
0.578 0.422 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.578 0.422 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.578 0.422 0.000
M90 Osteopathies in diseases classified elsewhere
0.578 0.422 0.000
M06.39 Rheumatoid nodule (Site unspecified)
0.578 0.422 0.000
M06.38 Rheumatoid nodule (Other)
0.578 0.422 0.000
M06.37 Rheumatoid nodule (Ankle and foot)
0.578 0.422 0.000
M06.36 Rheumatoid nodule (Lower leg)
0.578 0.422 0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.578 0.422 0.000
M06.33 Rheumatoid nodule (Forearm)
0.578 0.422 0.000
M06.32 Rheumatoid nodule (Upper arm)
0.578 0.422 0.000
M06.31 Rheumatoid nodule (Shoulder region)
0.578 0.422 0.000
M06.30 Rheumatoid nodule (Multiple sites)
0.578 0.422 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.578 0.422 0.000
L81 Other disorders of pigmentation
0.577 0.423 0.000
A49.3 Mycoplasma infection, unspecified
0.576 0.424 0.000
A49.2 Haemophilus influenzae infection, unspecified
0.576 0.424 0.000
M07.6 Other enteropathic arthropathies
0.576 0.424 0.000
M07.5 Arthropathy in ulcerative colitis
0.576 0.424 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.576 0.424 0.000
M07.2 Psoriatic spondylitis
0.576 0.424 0.000
M07.1 Arthritis mutilans
0.576 0.424 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.576 0.424 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.575 0.424 0.000
E45 Retarded development following protein-energy malnutrition
0.575 0.424 0.000
E43 Unspecified severe protein-energy malnutrition
0.575 0.424 0.000
E42 Marasmic kwashiorkor
0.575 0.424 0.000
E41 Nutritional marasmus
0.575 0.424 0.000
E40 Kwashiorkor
0.575 0.424 0.000
H57.9 Disorder of eye and adnexa, unspecified
0.575 0.425 0.000
L50-L54 Urticaria and erythema
0.575 0.425 0.000
M14.8 Arthropathies in other specified diseases classified elsewhere
0.575 0.425 0.000
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.575 0.425 0.000
M14.4 Arthropathy in amyloidosis
0.575 0.425 0.000
M14.3 Lipoid dermatoarthritis
0.575 0.425 0.000
M14.2 Diabetic arthropathy
0.575 0.425 0.000
M14.1 Crystal arthropathy in other metabolic disorders
0.575 0.425 0.000
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.575 0.425 0.000
F43.0 Acute stress reaction
0.575 0.425 0.000
S60 Superficial injury of wrist and hand
0.574 0.425 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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