TreeWAS – Variant ID: rs840016

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	0.666	0.334	0.000
E03 Other hypothyroidism	0.322	0.678	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.260	0.739	0.000
E03.5 Myxoedema coma	0.231	0.769	0.000
E03.4 Atrophy of thyroid (acquired)	0.231	0.769	0.000
E03.3 Postinfectious hypothyroidism	0.231	0.769	0.000
E03.1 Congenital hypothyroidism without goitre	0.230	0.770	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.226	0.773	0.000
E03.8 Other specified hypothyroidism	0.174	0.826	0.000
E00-E07 Disorders of thyroid gland	0.110	0.890	0.000
E20-E35 Disorders of other endocrine glands	0.096	0.904	0.000
E23 Hypofunction and other disorders of pituitary gland	0.095	0.905	0.000
E07 Other disorders of thyroid	0.093	0.907	0.000
E27 Other disorders of adrenal gland	0.092	0.908	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.091	0.909	0.000
E23.2 Diabetes insipidus	0.089	0.911	0.000
E26 Hyperaldosteronism	0.088	0.912	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.088	0.912	0.000
E07.9 Disorder of thyroid, unspecified	0.086	0.914	0.000
E23.0 Hypopituitarism	0.086	0.914	0.000
E26.0 Primary hyperaldosteronism	0.082	0.918	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.079	0.921	0.000
E00 Congenital iodine-deficiency syndrome	0.079	0.921	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.077	0.923	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.076	0.924	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.075	0.925	0.000
E29 Testicular dysfunction	0.075	0.925	0.000
E27.2 Addisonian crisis	0.074	0.926	0.000
E28 Ovarian dysfunction	0.073	0.927	0.000
E31 Polyglandular dysfunction	0.072	0.928	0.000
E21.3 Hyperparathyroidism, unspecified	0.070	0.930	0.000
E23.6 Other disorders of pituitary gland	0.070	0.930	0.000
E23.7 Disorder of pituitary gland, unspecified	0.069	0.931	0.000
E27.8 Other specified disorders of adrenal gland	0.069	0.931	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.069	0.931	0.000
E32 Diseases of thymus	0.069	0.931	0.000
E30 Disorders of puberty, not elsewhere classified	0.069	0.931	0.000
E06 Thyroiditis	0.069	0.931	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.068	0.932	0.000
E23.1 Drug-induced hypopituitarism	0.068	0.932	0.000
E25 Adrenogenital disorders	0.067	0.932	0.000
E07.1 Dyshormogenetic goitre	0.067	0.933	0.000
E07.0 Hypersecretion of calcitonin	0.067	0.933	0.000
E34 Other endocrine disorders	0.067	0.933	0.000
E27.5 Adrenomedullary hyperfunction	0.066	0.934	0.000
E27.0 Other adrenocortical overactivity	0.066	0.934	0.000
E22 Hyperfunction of pituitary gland	0.066	0.934	0.000
E26.9 Hyperaldosteronism, unspecified	0.065	0.935	0.000
E26.8 Other hyperaldosteronism	0.063	0.936	0.000
E26.1 Secondary hyperaldosteronism	0.063	0.936	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.061	0.939	0.000
E20 Hypoparathyroidism	0.061	0.939	0.000
E29.1 Testicular hypofunction	0.060	0.940	0.000
E27.9 Disorder of adrenal gland, unspecified	0.058	0.942	0.000
E28.2 Polycystic ovarian syndrome	0.058	0.942	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.057	0.943	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.057	0.943	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.057	0.943	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.057	0.943	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.057	0.943	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.057	0.943	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.057	0.943	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.057	0.943	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.057	0.943	0.000
E27.1 Primary adrenocortical insufficiency	0.056	0.944	0.000
J34.8 Other specified disorders of nose and nasal sinuses	0.000	0.944	0.056
E24 Cushing's syndrome	0.055	0.945	0.000
E31.0 Autoimmune polyglandular failure	0.054	0.946	0.000
E21.4 Other specified disorders of parathyroid gland	0.054	0.946	0.000
E29.9 Testicular dysfunction, unspecified	0.054	0.946	0.000
E29.8 Other testicular dysfunction	0.054	0.946	0.000
E29.0 Testicular hyperfunction	0.054	0.946	0.000
J33.9 Nasal polyp, unspecified	0.000	0.946	0.054
E06.9 Thyroiditis, unspecified	0.053	0.947	0.000
E28.9 Ovarian dysfunction, unspecified	0.053	0.947	0.000
E28.8 Other ovarian dysfunction	0.053	0.947	0.000
E28.1 Androgen excess	0.053	0.947	0.000
E28.0 Oestrogen excess	0.053	0.947	0.000
E07.8 Other specified disorders of thyroid	0.052	0.948	0.000
E06.1 Subacute thyroiditis	0.052	0.948	0.000
E22.0 Acromegaly and pituitary gigantism	0.052	0.948	0.000
E31.9 Polyglandular dysfunction, unspecified	0.051	0.948	0.000
E31.8 Other polyglandular dysfunction	0.051	0.948	0.000
E31.1 Polyglandular hyperfunction	0.051	0.948	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.051	0.949	0.000
E28.3 Primary ovarian failure	0.051	0.949	0.000
E06.5 Other chronic thyroiditis	0.051	0.949	0.000
J33 Nasal polyp	0.000	0.949	0.051
E21.2 Other hyperparathyroidism	0.050	0.950	0.000
E30.9 Disorder of puberty, unspecified	0.050	0.950	0.000
E30.8 Other disorders of puberty	0.050	0.950	0.000
E30.1 Precocious puberty	0.050	0.950	0.000
E30.0 Delayed puberty	0.050	0.950	0.000
E32.9 Disease of thymus, unspecified	0.050	0.950	0.000
E32.8 Other diseases of thymus	0.050	0.950	0.000
E32.1 Abscess of thymus	0.050	0.950	0.000
E32.0 Persistent hyperplasia of thymus	0.050	0.950	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.050	0.950	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.050	0.950	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.050	0.950	0.000
E06.4 Drug-induced thyroiditis	0.050	0.950	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.050	0.950	0.000
E06.0 Acute thyroiditis	0.050	0.950	0.000
E25.9 Adrenogenital disorder, unspecified	0.048	0.951	0.000
E25.8 Other adrenogenital disorders	0.048	0.951	0.000
E34.3 Short stature, not elsewhere classified	0.048	0.951	0.000
E20.1 Pseudohypoparathyroidism	0.048	0.952	0.000
E34.5 Androgen resistance syndrome	0.048	0.952	0.000
E34.4 Constitutional tall stature	0.048	0.952	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.048	0.952	0.000
E34.1 Other hypersecretion of intestinal hormones	0.048	0.952	0.000
E34.9 Endocrine disorder, unspecified	0.048	0.952	0.000
E34.0 Carcinoid syndrome	0.048	0.952	0.000
E22.1 Hyperprolactinaemia	0.048	0.952	0.000
J33.8 Other polyp of sinus	0.000	0.952	0.048
E22.8 Other hyperfunction of pituitary gland	0.048	0.952	0.000
J34 Other disorders of nose and nasal sinuses	0.000	0.953	0.047
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.047	0.953	0.000
E34.8 Other specified endocrine disorders	0.046	0.954	0.000
E40-E46 Malnutrition	0.045	0.955	0.000
E20.8 Other hypoparathyroidism	0.044	0.956	0.000
E20.0 Idiopathic hypoparathyroidism	0.044	0.956	0.000
E10-E14 Diabetes mellitus	0.043	0.957	0.000
J30-J39 Other diseases of upper respiratory tract	0.000	0.957	0.043
J34.0 Abscess, furuncle and carbuncle of nose	0.000	0.958	0.042
E10 Insulin-dependent diabetes mellitus	0.042	0.958	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.040	0.959	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.039	0.961	0.000
E24.3 Ectopic ACTH syndrome	0.039	0.961	0.000
E24.1 Nelson's syndrome	0.039	0.961	0.000
E10.5 With peripheral circulatory complications	0.039	0.961	0.000
E24.2 Drug-induced Cushing's syndrome	0.038	0.962	0.000
J32 Chronic sinusitis	0.000	0.962	0.038
E10.4 With neurological complications	0.037	0.963	0.000
E24.9 Cushing's syndrome, unspecified	0.037	0.963	0.000
E24.8 Other Cushing's syndrome	0.037	0.963	0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.000	0.963	0.037
J34.1 Cyst and mucocele of nose and nasal sinus	0.000	0.964	0.036
E10.8 With unspecified complications	0.036	0.964	0.000
J39 Other diseases of upper respiratory tract	0.000	0.964	0.036
E10.0 With coma	0.035	0.965	0.000
J33.0 Polyp of nasal cavity	0.000	0.965	0.035
E24.0 Pituitary-dependent Cushing's disease	0.034	0.965	0.000
E50-E64 Other nutritional deficiencies	0.034	0.966	0.000
J31.0 Chronic rhinitis	0.000	0.966	0.034
E10.2 With renal complications	0.034	0.966	0.000
J39.2 Other diseases of pharynx	0.000	0.966	0.034
J33.1 Polypoid sinus degeneration	0.000	0.966	0.034
J32.4 Chronic pansinusitis	0.000	0.966	0.034
E65-E68 Obesity and other hyperalimentation	0.033	0.967	0.000
E10.7 With multiple complications	0.033	0.967	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.033	0.967	0.000
E45 Retarded development following protein-energy malnutrition	0.033	0.967	0.000
E43 Unspecified severe protein-energy malnutrition	0.033	0.967	0.000
E42 Marasmic kwashiorkor	0.033	0.967	0.000
E41 Nutritional marasmus	0.033	0.967	0.000
E40 Kwashiorkor	0.033	0.967	0.000
J32.2 Chronic ethmoidal sinusitis	0.000	0.968	0.032
E10.6 With other specified complications	0.032	0.968	0.000
J37 Chronic laryngitis and laryngotracheitis	0.000	0.968	0.032
E21.0 Primary hyperparathyroidism	0.031	0.969	0.000
E12 Malnutrition-related diabetes mellitus	0.031	0.969	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.031	0.969	0.000
J32.1 Chronic frontal sinusitis	0.000	0.969	0.031
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.030	0.970	0.000
J32.0 Chronic maxillary sinusitis	0.000	0.970	0.030
E15 Nondiabetic hypoglycaemic coma	0.029	0.971	0.000
J39.9 Disease of upper respiratory tract, unspecified	0.000	0.972	0.028
J31.1 Chronic nasopharyngitis	0.000	0.972	0.027
E10.1 With ketoacidosis	0.027	0.973	0.000
J34.2 Deviated nasal septum	0.000	0.973	0.027
E54 Ascorbic acid deficiency	0.027	0.973	0.000
J32.3 Chronic sphenoidal sinusitis	0.000	0.973	0.027
E20.9 Hypoparathyroidism, unspecified	0.026	0.974	0.001
J39.0 Retropharyngeal and parapharyngeal abscess	0.000	0.974	0.026
J39.3 Upper respiratory tract hypersensitivity reaction, site unspecified	0.000	0.974	0.026
J32.8 Other chronic sinusitis	0.000	0.975	0.025
E64 Sequelae of malnutrition and other nutritional deficiencies	0.025	0.975	0.000
E63 Other nutritional deficiencies	0.025	0.975	0.000
E50 Vitamin A deficiency	0.025	0.975	0.000
E60 Dietary zinc deficiency	0.025	0.975	0.000
E59 Dietary selenium deficiency	0.025	0.975	0.000
E52 Niacin deficiency [pellagra]	0.025	0.975	0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.000	0.975	0.025
E51 Thiamine deficiency	0.024	0.976	0.000
E67 Other hyperalimentation	0.024	0.976	0.000
E68 Sequelae of hyperalimentation	0.024	0.976	0.000
J37.0 Chronic laryngitis	0.000	0.976	0.024
E46 Unspecified protein-energy malnutrition	0.024	0.976	0.000
E65 Localised adiposity	0.024	0.976	0.000
E44.1 Mild protein-energy malnutrition	0.023	0.976	0.000
E44.0 Moderate protein-energy malnutrition	0.023	0.976	0.000
E06.3 Autoimmune thyroiditis	0.024	0.976	0.000
J36 Peritonsillar abscess	0.000	0.976	0.023
J37.1 Chronic laryngotracheitis	0.000	0.977	0.023
E58 Dietary calcium deficiency	0.023	0.977	0.000
J38.0 Paralysis of vocal cords and larynx	0.000	0.977	0.023
E12.9 Without complications	0.022	0.977	0.000
E12.8 With unspecified complications	0.022	0.977	0.000
E12.7 With multiple complications	0.022	0.977	0.000
E12.6 With other specified complications	0.022	0.977	0.000
E12.5 With peripheral circulatory complications	0.022	0.977	0.000
E12.4 With neurological complications	0.022	0.977	0.000
E12.3 With ophthalmic complications	0.022	0.977	0.000
E12.2 With renal complications	0.022	0.977	0.000
E12.1 With ketoacidosis	0.022	0.977	0.000
E12.0 With coma	0.022	0.977	0.000
E56 Other vitamin deficiencies	0.022	0.978	0.000
E61 Deficiency of other nutrient elements	0.022	0.978	0.000
E13 Other specified diabetes mellitus	0.021	0.978	0.000
J39.1 Other abscess of pharynx	0.000	0.979	0.021
E55 Vitamin D deficiency	0.021	0.979	0.000
E53 Deficiency of other B group vitamins	0.021	0.979	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.020	0.980	0.000
J38.5 Laryngeal spasm	0.000	0.980	0.020
J38.1 Polyp of vocal cord and larynx	0.000	0.981	0.019
J31.2 Chronic pharyngitis	0.000	0.981	0.019
E53.9 Vitamin B deficiency, unspecified	0.018	0.982	0.000
E50.9 Vitamin A deficiency, unspecified	0.018	0.982	0.000
E50.8 Other manifestations of vitamin A deficiency	0.018	0.982	0.000
E50.7 Other ocular manifestations of vitamin A deficiency	0.018	0.982	0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.018	0.982	0.000
E50.5 Vitamin A deficiency with night blindness	0.018	0.982	0.000
E50.4 Vitamin A deficiency with keratomalacia	0.018	0.982	0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.018	0.982	0.000
E50.2 Vitamin A deficiency with corneal xerosis	0.018	0.982	0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.018	0.982	0.000
E50.0 Vitamin A deficiency with conjunctival xerosis	0.018	0.982	0.000
E63.9 Nutritional deficiency, unspecified	0.018	0.982	0.000
E63.8 Other specified nutritional deficiencies	0.018	0.982	0.000
E63.1 Imbalance of constituents of food intake	0.018	0.982	0.000
E63.0 Essential fatty acid [EFA] deficiency	0.018	0.982	0.000
E64.9 Sequelae of unspecified nutritional deficiency	0.018	0.982	0.000
E64.8 Sequelae of other nutritional deficiencies	0.018	0.982	0.000
E64.3 Sequelae of rickets	0.018	0.982	0.000
E64.2 Sequelae of vitamin C deficiency	0.018	0.982	0.000
E64.1 Sequelae of vitamin A deficiency	0.018	0.982	0.000
E64.0 Sequelae of protein-energy malnutrition	0.018	0.982	0.000
E51.9 Thiamine deficiency, unspecified	0.017	0.982	0.000
E51.8 Other manifestations of thiamine deficiency	0.017	0.982	0.000
E51.1 Beriberi	0.017	0.982	0.000
E67.8 Other specified hyperalimentation	0.017	0.982	0.000
E67.3 Hypervitaminosis D	0.017	0.982	0.000
E67.2 Megavitamin-B6 syndrome	0.017	0.982	0.000
E67.1 Hypercarotenaemia	0.017	0.982	0.000
E67.0 Hypervitaminosis A	0.017	0.982	0.000
E51.2 Wernicke's encephalopathy	0.017	0.983	0.000
E11.2 With renal complications	0.017	0.983	0.000
E61.1 Iron deficiency	0.017	0.983	0.000
J38.2 Nodules of vocal cords	0.000	0.983	0.017
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.017	0.983	0.000
E11 Non-insulin-dependent diabetes mellitus	0.016	0.984	0.000
E56.9 Vitamin deficiency, unspecified	0.016	0.984	0.000
E56.8 Deficiency of other vitamins	0.016	0.984	0.000
E56.0 Deficiency of vitamin E	0.016	0.984	0.000
E61.9 Deficiency of nutrient element, unspecified	0.016	0.984	0.000
E61.8 Deficiency of other specified nutrient elements	0.016	0.984	0.000
E61.7 Deficiency of multiple nutrient elements	0.016	0.984	0.000
E61.6 Vanadium deficiency	0.016	0.984	0.000
E61.5 Molybdenum deficiency	0.016	0.984	0.000
E61.4 Chromium deficiency	0.016	0.984	0.000
E61.3 Manganese deficiency	0.016	0.984	0.000
E61.0 Copper deficiency	0.016	0.984	0.000
E16 Other disorders of pancreatic internal secretion	0.016	0.984	0.000
E13.8 With unspecified complications	0.015	0.984	0.000
E13.7 With multiple complications	0.015	0.984	0.000
E13.6 With other specified complications	0.015	0.984	0.000
E13.5 With peripheral circulatory complications	0.015	0.984	0.000
E13.4 With neurological complications	0.015	0.984	0.000
E13.2 With renal complications	0.015	0.984	0.000
E13.1 With ketoacidosis	0.015	0.984	0.000
E13.0 With coma	0.015	0.984	0.000
E14 Unspecified diabetes mellitus	0.016	0.984	0.000
E55.0 Rickets, active	0.015	0.984	0.000
E53.1 Pyridoxine deficiency	0.015	0.985	0.000
E53.0 Riboflavin deficiency	0.015	0.985	0.000
J38.3 Other diseases of vocal cords	0.000	0.985	0.015
E13.3 With ophthalmic complications	0.015	0.985	0.000
E05.5 Thyroid crisis or storm	0.015	0.985	0.000
E05.4 Thyrotoxicosis factitia	0.015	0.985	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.015	0.985	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.015	0.985	0.000
E14.8 With unspecified complications	0.015	0.985	0.000
J38.6 Stenosis of larynx	0.000	0.985	0.014
C82.3 Follicular lymphoma grade IIIa	0.014	0.986	0.000
E05.8 Other thyrotoxicosis	0.014	0.986	0.000
E11.8 With unspecified complications	0.014	0.986	0.000
L50.9 Urticaria, unspecified	0.000	0.986	0.014
Z35.1 Supervision of pregnancy with history of abortive outcome	0.000	0.987	0.013
E56.1 Deficiency of vitamin K	0.013	0.987	0.000
J39.8 Other specified diseases of upper respiratory tract	0.000	0.987	0.013
C82.4 Follicular lymphoma grade IIIb	0.013	0.987	0.000
C82.2 Large cell, follicular	0.013	0.987	0.000
E11.6 With other specified complications	0.013	0.987	0.000
J38.4 Oedema of larynx	0.000	0.987	0.012
I98.2 Oesophageal varices in diseases classified elsewhere	0.012	0.988	0.000
C82.6 Cutaneous follicle centre lymphoma	0.012	0.988	0.000
C82.5 Diffuse follicle centre lymphoma	0.012	0.988	0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.012	0.988	0.000
E11.7 With multiple complications	0.012	0.988	0.000
E55.9 Vitamin D deficiency, unspecified	0.012	0.988	0.000
E61.2 Magnesium deficiency	0.011	0.988	0.000
C82.0 Small cleaved cell, follicular	0.012	0.988	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.011	0.988	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.011	0.988	0.000
E16.4 Abnormal secretion of gastrin	0.011	0.988	0.000
E16.3 Increased secretion of glucagon	0.011	0.988	0.000
E14.7 With multiple complications	0.011	0.988	0.000
E14.0 With coma	0.011	0.988	0.000
I98 Other disorders of circulatory system in diseases classified elsewhere	0.011	0.988	0.000
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.011	0.989	0.000
E14.1 With ketoacidosis	0.011	0.989	0.000
E11.0 With coma	0.011	0.989	0.000
E05.9 Thyrotoxicosis, unspecified	0.011	0.989	0.000
E04 Other non-toxic goitre	0.011	0.989	0.000
E14.4 With neurological complications	0.011	0.989	0.000
E70-E90 Metabolic disorders	0.011	0.989	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.011	0.989	0.000
E16.1 Other hypoglycaemia	0.010	0.989	0.000
E14.6 With other specified complications	0.010	0.990	0.000
E14.5 With peripheral circulatory complications	0.010	0.990	0.000
I95.1 Orthostatic hypotension	0.010	0.990	0.000
J30 Vasomotor and allergic rhinitis	0.000	0.990	0.010
I95.2 Hypotension due to drugs	0.010	0.990	0.000
E14.3 With ophthalmic complications	0.010	0.990	0.000
N87.9 Dysplasia of cervix uteri, unspecified	0.010	0.990	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.009	0.990	0.000
E80.4 Gilbert's syndrome	0.009	0.991	0.000
C82.1 Mixed small cleaved and large cell, follicular	0.009	0.991	0.000
E14.2 Withrenal complications	0.009	0.991	0.000
J45.9 Asthma, unspecified	0.000	0.991	0.009
E80.2 Other porphyria	0.009	0.991	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.009	0.991	0.000
J32.9 Chronic sinusitis, unspecified	0.000	0.991	0.009
I95 Hypotension	0.009	0.991	0.000
E80.1 Porphyria cutanea tarda	0.009	0.991	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.009	0.991	0.000
J34.3 Hypertrophy of nasal turbinates	0.000	0.991	0.009
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.008	0.991	0.000
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.008	0.991	0.000
I98.0 Cardiovascular syphilis	0.008	0.991	0.000
E80.7 Disorder of bilirubin metabolism, unspecified	0.008	0.992	0.000
E10.3 With ophthalmic complications	0.008	0.992	0.000
E11.4 With neurological complications	0.008	0.992	0.000
E11.3 With ophthalmic complications	0.008	0.992	0.000
E04.8 Other specified non-toxic goitre	0.008	0.992	0.000
E72 Other disorders of amino-acid metabolism	0.008	0.992	0.000
J30.0 Vasomotor rhinitis	0.000	0.992	0.008
F00.9 Dementia in Alzheimer's disease, unspecified	0.000	0.992	0.008
E77 Disorders of glycoprotein metabolism	0.008	0.992	0.000
E76 Disorders of glycosaminoglycan metabolism	0.008	0.992	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.008	0.992	0.000
E70 Disorders of aromatic amino-acid metabolism	0.008	0.992	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.008	0.992	0.000
E89.3 Postprocedural hypopituitarism	0.008	0.992	0.000
E89.8 Other postprocedural endocrine and metabolic disorders	0.008	0.992	0.000
E80.5 Crigler-Najjar syndrome	0.008	0.992	0.000
E80.3 Defects of catalase and peroxydase	0.008	0.992	0.000
E80.0 Hereditary erythropoietic porphyria	0.008	0.992	0.000
E80.6 Other disorders of bilirubin metabolism	0.008	0.992	0.000
E85 Amyloidosis	0.008	0.992	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.008	0.992	0.000
J30.2 Other seasonal allergic rhinitis	0.000	0.992	0.008
E13.9 Without complications	0.007	0.992	0.000
E88 Other metabolic disorders	0.008	0.992	0.000
E74 Other disorders of carbohydrate metabolism	0.008	0.992	0.000
J38.7 Other diseases of larynx	0.000	0.992	0.008
C16.0 Cardia	0.008	0.992	0.000
E79 Disorders of purine and pyrimidine metabolism	0.007	0.992	0.000
C16.9 Stomach, unspecified	0.007	0.993	0.000
E84 Cystic fibrosis	0.007	0.993	0.000
C16 Malignant neoplasm of stomach	0.007	0.993	0.000
E04.0 Non-toxic diffuse goitre	0.007	0.993	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.007	0.993	0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.007	0.993	0.000
I95.0 Idiopathic hypotension	0.007	0.993	0.000
E89.5 Postprocedural testicular hypofunction	0.007	0.993	0.000
C16.5 Lesser curvature of stomach, unspecified	0.007	0.993	0.000
E89.1 Postprocedural hypoinsulinaemia	0.007	0.993	0.000
E11.1 With ketoacidosis	0.007	0.993	0.000
E89.4 Postprocedural ovarian failure	0.007	0.993	0.000
W06.0 Home	0.007	0.993	0.000
E88.8 Other specified metabolic disorders	0.007	0.993	0.000
E88.3 Tumour lysis syndrome	0.006	0.993	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.006	0.993	0.000
E74.0 Glycogen storage disease	0.006	0.994	0.000
E85.3 Secondary systemic amyloidosis	0.006	0.994	0.000
J30.4 Allergic rhinitis, unspecified	0.000	0.994	0.006
J35 Chronic diseases of tonsils and adenoids	0.000	0.994	0.006
C16.6 Greater curvature of stomach, unspecified	0.006	0.994	0.000
E73 Lactose intolerance	0.006	0.994	0.000
E72.0 Disorders of amino-acid transport	0.006	0.994	0.000
C16.3 Pyloric antrum	0.006	0.994	0.000
E72.9 Disorder of amino-acid metabolism, unspecified	0.006	0.994	0.000
E72.8 Other specified disorders of amino-acid metabolism	0.006	0.994	0.000
E72.5 Disorders of glycine metabolism	0.006	0.994	0.000
E72.4 Disorders of ornithine metabolism	0.006	0.994	0.000
E72.3 Disorders of lysine and hydroxylysine metabolism	0.006	0.994	0.000
E72.2 Disorders of urea cycle metabolism	0.006	0.994	0.000
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.006	0.994	0.000
E88.9 Metabolic disorder, unspecified	0.006	0.994	0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.006	0.994	0.000
E70.8 Other disorders of aromatic amino-acid metabolism	0.006	0.994	0.000
E70.3 Albinism	0.006	0.994	0.000
E70.2 Disorders of tyrosine metabolism	0.006	0.994	0.000
E70.1 Other hyperphenylalaninaemias	0.006	0.994	0.000
E70.0 Classical phenylketonuria	0.006	0.994	0.000
E71.3 Disorders of fatty-acid metabolism	0.006	0.994	0.000
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.006	0.994	0.000
E71.1 Other disorders of branched-chain amino-acid metabolism	0.006	0.994	0.000
E71.0 Maple-syrup-urine disease	0.006	0.994	0.000
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.006	0.994	0.000
E76.8 Other disorders of glucosaminoglycan metabolism	0.006	0.994	0.000
E76.3 Mucopolysaccharidosis, unspecified	0.006	0.994	0.000
E76.2 Other mucopolysaccharidoses	0.006	0.994	0.000
E76.1 Mucopolysaccharidosis, type II	0.006	0.994	0.000
E76.0 Mucopolysaccharidosis, type I	0.006	0.994	0.000
E77.9 Disorder of glycoprotein metabolism, unspecified	0.006	0.994	0.000
E77.8 Other disorders of glycoprotein metabolism	0.006	0.994	0.000
E77.1 Defects in glycoprotein degradation	0.006	0.994	0.000
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.006	0.994	0.000
E75.2 Other sphingolipidosis	0.006	0.994	0.000
E85.8 Other amyloidosis	0.006	0.994	0.000
E85.2 Heredofamilial amyloidosis, unspecified	0.006	0.994	0.000
E85.1 Neuropathic heredofamilial amyloidosis	0.006	0.994	0.000
E85.0 Nonneuropathic heredofamilial amyloidosis	0.006	0.994	0.000
E86 Volume depletion	0.006	0.994	0.000
E75.6 Lipid storage disorder, unspecified	0.006	0.994	0.000
E75.4 Neuronal ceroid lipofuscinosis	0.006	0.994	0.000
E75.3 Sphingolipidosis, unspecified	0.006	0.994	0.000
E75.1 Other gangliosidosis	0.006	0.994	0.000
E75.0 GM2 gangliosidosis	0.006	0.994	0.000
L72.0 Epidermal cyst	0.006	0.994	0.000
E85.9 Amyloidosis, unspecified	0.006	0.994	0.000
E88.1 Lipodystrophy, not elsewhere classified	0.006	0.994	0.000
E74.9 Disorder of carbohydrate metabolism, unspecified	0.006	0.994	0.000
E74.8 Other specified disorders of carbohydrate metabolism	0.006	0.994	0.000
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.006	0.994	0.000
E74.2 Disorders of galactose metabolism	0.006	0.994	0.000
E74.1 Disorders of fructose metabolism	0.006	0.994	0.000
E75.5 Other lipid storage disorders	0.005	0.994	0.000
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.005	0.994	0.000
E79.8 Other disorders of purine and pyrimidine metabolism	0.005	0.994	0.000
E79.1 Lesch-Nyhan syndrome	0.005	0.994	0.000
C16.1 Fundus of stomach	0.006	0.994	0.000
E84.8 Cystic fibrosis with other manifestations	0.005	0.994	0.000
E84.1 Cystic fibrosis with intestinal manifestations	0.005	0.994	0.000
E84.0 Cystic fibrosis with pulmonary manifestations	0.005	0.994	0.000
C16.8 Overlapping lesion of stomach	0.005	0.994	0.000
E16.2 Hypoglycaemia, unspecified	0.006	0.994	0.000
K90.0 Coeliac disease	0.000	0.995	0.005
E88.2 Lipomatosis, not elsewhere classified	0.005	0.995	0.000
C16.2 Body of stomach	0.005	0.995	0.000
M13.96 Arthritis, unspecified (Lower leg)	0.005	0.995	0.000
C16.4 Pylorus	0.005	0.995	0.000
L50 Urticaria	0.000	0.995	0.005
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.005	0.995	0.000
E85.4 Organ-limited amyloidosis	0.005	0.995	0.000
E87.6 Hypokalaemia	0.005	0.995	0.000
E84.9 Cystic fibrosis, unspecified	0.005	0.995	0.000
E04.2 Non-toxic multinodular goitre	0.005	0.995	0.000
E11.5 With peripheral circulatory complications	0.005	0.995	0.000
J35.3 Hypertrophy of tonsils with hypertrophy of adenoids	0.000	0.995	0.005
E73.8 Other lactose intolerance	0.004	0.995	0.000
E73.1 Secondary lactase deficiency	0.004	0.995	0.000
E73.0 Congenital lactase deficiency	0.004	0.995	0.000
F00 Dementia in Alzheimer's disease	0.000	0.995	0.005
J35.9 Chronic disease of tonsils and adenoids, unspecified	0.000	0.995	0.004
Z35 Supervision of high-risk pregnancy	0.000	0.995	0.005
L50.8 Other urticaria	0.000	0.995	0.004
O70.0 First degree perineal laceration during delivery	0.000	0.996	0.004
E74.3 Other disorders of intestinal carbohydrate absorption	0.004	0.996	0.000
E83.1 Disorders of iron metabolism	0.004	0.996	0.000
E83 Disorders of mineral metabolism	0.004	0.996	0.000
E66 Obesity	0.004	0.996	0.000
F00.0 Dementia in Alzheimer's disease with early onset	0.000	0.996	0.004
I95.8 Other hypotension	0.004	0.996	0.000
L50.6 Contact urticaria	0.000	0.996	0.004
L50.5 Cholinergic urticaria	0.000	0.996	0.004
L50.4 Vibratory urticaria	0.000	0.996	0.004
L50.3 Dermatographic urticaria	0.000	0.996	0.004
L50.2 Urticaria due to cold and heat	0.000	0.996	0.004
J35.2 Hypertrophy of adenoids	0.000	0.996	0.004
Z35.4 Supervision of pregnancy with grand multiparity	0.000	0.996	0.004
Z35.0 Supervision of pregnancy with history of infertility	0.000	0.996	0.004
E87 Other disorders of fluid, electrolyte and acid-base balance	0.004	0.996	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.004	0.996	0.000
E89.2 Postprocedural hypoparathyroidism	0.003	0.996	0.000
F00.1 Dementia in Alzheimer's disease with late onset	0.000	0.996	0.004
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.004	0.996	0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.004	0.996	0.000
Z35.7 Supervision of high-risk pregnancy due to social problems	0.000	0.996	0.003
Z35.6 Supervision of very young primigravida	0.000	0.996	0.003
Z35.3 Supervision of pregnancy with history of insufficient antenatal care	0.000	0.996	0.003
F00.2 Dementia in Alzheimer's disease, atypical or mixed type	0.000	0.996	0.003
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.003	0.997	0.000
L50.1 Idiopathic urticaria	0.000	0.997	0.003
W06 Fall involving bed	0.003	0.997	0.000
N08.3 Glomerular disorders in diabetes mellitus	0.003	0.997	0.000
L50.0 Allergic urticaria	0.000	0.997	0.003

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations