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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs849140
log Bayes Factor = 9.55396
Chromosome 7   position 28,183,702  (GRCh37) Explore rs849140 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E11.9 Without complications
1.000 0.000 0.000
E11 Non-insulin-dependent diabetes mellitus
0.967 0.033 0.000
E11.4 With neurological complications
0.942 0.058 0.000
E11.3 With ophthalmic complications
0.916 0.084 0.000
E11.8 With unspecified complications
0.841 0.159 0.000
E10-E14 Diabetes mellitus
0.814 0.186 0.000
E10 Insulin-dependent diabetes mellitus
0.749 0.251 0.000
E10.5 With peripheral circulatory complications
0.700 0.300 0.000
E11.7 With multiple complications
0.693 0.307 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.668 0.332 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.655 0.345 0.000
E10.8 With unspecified complications
0.635 0.365 0.000
E10.4 With neurological complications
0.635 0.365 0.000
E00-E07 Disorders of thyroid gland
0.600 0.400 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.595 0.405 0.000
E05.9 Thyrotoxicosis, unspecified
0.591 0.409 0.000
E10.9 Without complications
0.588 0.412 0.000
E10.6 With other specified complications
0.587 0.413 0.000
E12 Malnutrition-related diabetes mellitus
0.583 0.417 0.000
E13 Other specified diabetes mellitus
0.564 0.436 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.563 0.437 0.000
E10.0 With coma
0.556 0.444 0.000
E11.6 With other specified complications
0.554 0.446 0.000
E11.0 With coma
0.537 0.462 0.000
E10.7 With multiple complications
0.537 0.463 0.000
E10.2 With renal complications
0.521 0.479 0.000
E11.5 With peripheral circulatory complications
0.508 0.492 0.000
E05.5 Thyroid crisis or storm
0.470 0.530 0.000
E05.4 Thyrotoxicosis factitia
0.470 0.530 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.470 0.530 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.470 0.530 0.000
E06 Thyroiditis
0.467 0.533 0.000
E05.8 Other thyrotoxicosis
0.465 0.535 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.444 0.556 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.440 0.560 0.000
E14 Unspecified diabetes mellitus
0.435 0.565 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.430 0.570 0.000
E00 Congenital iodine-deficiency syndrome
0.430 0.570 0.000
E13.3 With ophthalmic complications
0.430 0.570 0.000
E40-E46 Malnutrition
0.429 0.571 0.000
E06.9 Thyroiditis, unspecified
0.423 0.577 0.000
E12.9 Without complications
0.418 0.582 0.000
E12.8 With unspecified complications
0.418 0.582 0.000
E12.7 With multiple complications
0.418 0.582 0.000
E12.6 With other specified complications
0.418 0.582 0.000
E12.5 With peripheral circulatory complications
0.418 0.582 0.000
E12.4 With neurological complications
0.418 0.582 0.000
E12.3 With ophthalmic complications
0.418 0.582 0.000
E12.2 With renal complications
0.418 0.582 0.000
E12.1 With ketoacidosis
0.418 0.582 0.000
E12.0 With coma
0.418 0.582 0.000
E50-E64 Other nutritional deficiencies
0.411 0.589 0.000
E13.8 With unspecified complications
0.404 0.595 0.000
E13.7 With multiple complications
0.404 0.595 0.000
E13.6 With other specified complications
0.404 0.595 0.000
E13.5 With peripheral circulatory complications
0.404 0.595 0.000
E13.4 With neurological complications
0.404 0.595 0.000
E13.2 With renal complications
0.404 0.595 0.000
E13.1 With ketoacidosis
0.404 0.595 0.000
E13.0 With coma
0.404 0.595 0.000
E11.1 With ketoacidosis
0.397 0.602 0.000
E06.5 Other chronic thyroiditis
0.369 0.631 0.000
E14.6 With other specified complications
0.352 0.648 0.000
E13.9 Without complications
0.351 0.649 0.000
E14.8 With unspecified complications
0.335 0.664 0.000
E06.4 Drug-induced thyroiditis
0.335 0.665 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.335 0.665 0.000
E06.0 Acute thyroiditis
0.335 0.665 0.000
E54 Ascorbic acid deficiency
0.330 0.670 0.000
E16 Other disorders of pancreatic internal secretion
0.329 0.671 0.000
E11.2 With renal complications
0.327 0.673 0.000
E14.2 Withrenal complications
0.326 0.674 0.000
E06.1 Subacute thyroiditis
0.326 0.674 0.000
E14.1 With ketoacidosis
0.322 0.677 0.000
E14.4 With neurological complications
0.319 0.681 0.000
E15 Nondiabetic hypoglycaemic coma
0.316 0.684 0.000
E14.7 With multiple complications
0.312 0.688 0.000
E14.0 With coma
0.312 0.688 0.000
E63 Other nutritional deficiencies
0.311 0.689 0.000
E46 Unspecified protein-energy malnutrition
0.310 0.690 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.308 0.691 0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.308 0.691 0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.308 0.691 0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.308 0.691 0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.308 0.691 0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.308 0.691 0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.308 0.691 0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.308 0.691 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.308 0.692 0.000
E45 Retarded development following protein-energy malnutrition
0.308 0.692 0.000
E43 Unspecified severe protein-energy malnutrition
0.308 0.692 0.000
E42 Marasmic kwashiorkor
0.308 0.692 0.000
E41 Nutritional marasmus
0.308 0.692 0.000
E40 Kwashiorkor
0.308 0.692 0.000
E51 Thiamine deficiency
0.305 0.695 0.000
E53 Deficiency of other B group vitamins
0.302 0.698 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.295 0.705 0.000
E56 Other vitamin deficiencies
0.295 0.705 0.000
E50 Vitamin A deficiency
0.295 0.705 0.000
E60 Dietary zinc deficiency
0.295 0.705 0.000
E59 Dietary selenium deficiency
0.295 0.705 0.000
E52 Niacin deficiency [pellagra]
0.295 0.705 0.000
E14.5 With peripheral circulatory complications
0.292 0.708 0.000
E03 Other hypothyroidism
0.287 0.713 0.000
E58 Dietary calcium deficiency
0.283 0.717 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.279 0.721 0.000
E53.9 Vitamin B deficiency, unspecified
0.276 0.724 0.000
E10.1 With ketoacidosis
0.275 0.725 0.000
E07 Other disorders of thyroid
0.272 0.728 0.000
E61 Deficiency of other nutrient elements
0.269 0.730 0.000
E65-E68 Obesity and other hyperalimentation
0.256 0.744 0.000
E63.9 Nutritional deficiency, unspecified
0.240 0.760 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.236 0.764 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.236 0.764 0.000
E16.4 Abnormal secretion of gastrin
0.236 0.764 0.000
E16.3 Increased secretion of glucagon
0.236 0.764 0.000
E16.1 Other hypoglycaemia
0.231 0.769 0.000
E51.2 Wernicke's encephalopathy
0.228 0.771 0.000
E63.8 Other specified nutritional deficiencies
0.223 0.776 0.000
E63.1 Imbalance of constituents of food intake
0.223 0.776 0.000
E63.0 Essential fatty acid [EFA] deficiency
0.223 0.776 0.000
E61.2 Magnesium deficiency
0.223 0.777 0.000
E55 Vitamin D deficiency
0.221 0.779 0.000
E44.1 Mild protein-energy malnutrition
0.221 0.779 0.000
E44.0 Moderate protein-energy malnutrition
0.221 0.779 0.000
E51.9 Thiamine deficiency, unspecified
0.219 0.781 0.000
E51.8 Other manifestations of thiamine deficiency
0.219 0.781 0.000
E51.1 Beriberi
0.219 0.781 0.000
E53.1 Pyridoxine deficiency
0.217 0.783 0.000
E53.0 Riboflavin deficiency
0.217 0.783 0.000
E03.8 Other specified hypothyroidism
0.215 0.785 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.215 0.785 0.000
E50.9 Vitamin A deficiency, unspecified
0.212 0.788 0.000
E50.8 Other manifestations of vitamin A deficiency
0.212 0.788 0.000
E50.7 Other ocular manifestations of vitamin A deficiency
0.212 0.788 0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.212 0.788 0.000
E50.5 Vitamin A deficiency with night blindness
0.212 0.788 0.000
E50.4 Vitamin A deficiency with keratomalacia
0.212 0.788 0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.212 0.788 0.000
E50.2 Vitamin A deficiency with corneal xerosis
0.212 0.788 0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.212 0.788 0.000
E50.0 Vitamin A deficiency with conjunctival xerosis
0.212 0.788 0.000
E56.9 Vitamin deficiency, unspecified
0.212 0.788 0.000
E56.8 Deficiency of other vitamins
0.212 0.788 0.000
E56.1 Deficiency of vitamin K
0.212 0.788 0.000
E56.0 Deficiency of vitamin E
0.212 0.788 0.000
E64.9 Sequelae of unspecified nutritional deficiency
0.212 0.788 0.000
E64.8 Sequelae of other nutritional deficiencies
0.212 0.788 0.000
E64.3 Sequelae of rickets
0.212 0.788 0.000
E64.2 Sequelae of vitamin C deficiency
0.212 0.788 0.000
E64.1 Sequelae of vitamin A deficiency
0.212 0.788 0.000
E64.0 Sequelae of protein-energy malnutrition
0.212 0.788 0.000
E04 Other non-toxic goitre
0.210 0.790 0.000
E03.5 Myxoedema coma
0.206 0.794 0.000
E03.4 Atrophy of thyroid (acquired)
0.206 0.794 0.000
E03.3 Postinfectious hypothyroidism
0.206 0.794 0.000
E03.1 Congenital hypothyroidism without goitre
0.206 0.794 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.206 0.794 0.000
E10.3 With ophthalmic complications
0.195 0.804 0.000
E07.1 Dyshormogenetic goitre
0.195 0.805 0.000
E07.0 Hypersecretion of calcitonin
0.195 0.805 0.000
E61.9 Deficiency of nutrient element, unspecified
0.193 0.807 0.000
E61.8 Deficiency of other specified nutrient elements
0.193 0.807 0.000
E61.7 Deficiency of multiple nutrient elements
0.193 0.807 0.000
E61.6 Vanadium deficiency
0.193 0.807 0.000
E61.5 Molybdenum deficiency
0.193 0.807 0.000
E61.4 Chromium deficiency
0.193 0.807 0.000
E61.3 Manganese deficiency
0.193 0.807 0.000
E61.0 Copper deficiency
0.193 0.807 0.000
E07.8 Other specified disorders of thyroid
0.189 0.811 0.000
E16.2 Hypoglycaemia, unspecified
0.187 0.813 0.000
E67 Other hyperalimentation
0.184 0.816 0.000
E68 Sequelae of hyperalimentation
0.184 0.816 0.000
E65 Localised adiposity
0.177 0.823 0.000
E14.9 Without complications
0.174 0.826 0.000
E14.3 With ophthalmic complications
0.171 0.829 0.000
E04.0 Non-toxic diffuse goitre
0.161 0.839 0.000
E55.0 Rickets, active
0.159 0.841 0.000
E04.8 Other specified non-toxic goitre
0.151 0.849 0.000
E67.8 Other specified hyperalimentation
0.132 0.868 0.000
E67.3 Hypervitaminosis D
0.132 0.868 0.000
E67.2 Megavitamin-B6 syndrome
0.132 0.868 0.000
E67.1 Hypercarotenaemia
0.132 0.868 0.000
E67.0 Hypervitaminosis A
0.132 0.868 0.000
E04.9 Non-toxic goitre, unspecified
0.131 0.869 0.000
E06.3 Autoimmune thyroiditis
0.113 0.886 0.001
E61.1 Iron deficiency
0.105 0.895 0.000
E04.2 Non-toxic multinodular goitre
0.104 0.896 0.000
M48.06 Spinal stenosis (Lumbar region)
0.102 0.898 0.000
M48.0 Spinal stenosis
0.090 0.910 0.000
E55.9 Vitamin D deficiency, unspecified
0.084 0.915 0.000
M48.00 Spinal stenosis (Multiple sites in spine)
0.080 0.920 0.000
M48.09 Spinal stenosis (Site unspecified)
0.076 0.924 0.000
M48.07 Spinal stenosis (Lumbosacral region)
0.072 0.928 0.000
M48.04 Spinal stenosis (Thoracic region)
0.069 0.931 0.000
M48.05 Spinal stenosis (Thoracolumbar region)
0.067 0.933 0.000
E04.1 Non-toxic single thyroid nodule
0.067 0.933 0.000
M48.03 Spinal stenosis (Cervicothoracic region)
0.064 0.936 0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)
0.064 0.936 0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)
0.064 0.936 0.000
E20-E35 Disorders of other endocrine glands
0.064 0.936 0.000
E07.9 Disorder of thyroid, unspecified
0.052 0.948 0.000
E20 Hypoparathyroidism
0.052 0.948 0.000
E26 Hyperaldosteronism
0.051 0.949 0.000
E25 Adrenogenital disorders
0.050 0.950 0.000
E34 Other endocrine disorders
0.047 0.953 0.000
M48 Other spondylopathies
0.046 0.954 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.046 0.954 0.000
E32 Diseases of thymus
0.046 0.954 0.000
E31 Polyglandular dysfunction
0.046 0.954 0.000
E30 Disorders of puberty, not elsewhere classified
0.046 0.954 0.000
M48.02 Spinal stenosis (Cervical region)
0.046 0.954 0.000
E20.9 Hypoparathyroidism, unspecified
0.044 0.956 0.000
E53.8 Deficiency of other specified B group vitamins
0.044 0.956 0.000
E26.9 Hyperaldosteronism, unspecified
0.043 0.957 0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.040 0.960 0.000
D36.1 Peripheral nerves and autonomic nervous system
0.000 0.961 0.039
E28 Ovarian dysfunction
0.039 0.961 0.000
E20.8 Other hypoparathyroidism
0.038 0.962 0.000
E20.1 Pseudohypoparathyroidism
0.038 0.962 0.000
E20.0 Idiopathic hypoparathyroidism
0.038 0.962 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.037 0.963 0.000
E24 Cushing's syndrome
0.037 0.963 0.000
E26.8 Other hyperaldosteronism
0.037 0.963 0.000
E26.1 Secondary hyperaldosteronism
0.037 0.963 0.000
M48.8 Other specified spondylopathies
0.036 0.964 0.000
E25.9 Adrenogenital disorder, unspecified
0.036 0.964 0.000
E25.8 Other adrenogenital disorders
0.036 0.964 0.000
E34.9 Endocrine disorder, unspecified
0.035 0.964 0.000
E26.0 Primary hyperaldosteronism
0.035 0.965 0.000
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)
0.035 0.965 0.000
E66 Obesity
0.035 0.965 0.000
E34.3 Short stature, not elsewhere classified
0.034 0.966 0.000
E34.5 Androgen resistance syndrome
0.034 0.966 0.000
E34.4 Constitutional tall stature
0.034 0.966 0.000
E34.2 Ectopic hormone secretion, not elsewhere classified
0.034 0.966 0.000
E34.1 Other hypersecretion of intestinal hormones
0.034 0.966 0.000
E29 Testicular dysfunction
0.034 0.966 0.000
E34.0 Carcinoid syndrome
0.033 0.967 0.000
E34.8 Other specified endocrine disorders
0.033 0.967 0.000
M48.4 Fatigue fracture of vertebra
0.033 0.967 0.000
M48.3 Traumatic spondylopathy
0.033 0.967 0.000
M48.2 Kissing spine
0.033 0.967 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.033 0.967 0.000
E30.9 Disorder of puberty, unspecified
0.033 0.967 0.000
E30.8 Other disorders of puberty
0.033 0.967 0.000
E30.1 Precocious puberty
0.033 0.967 0.000
E30.0 Delayed puberty
0.033 0.967 0.000
E31.9 Polyglandular dysfunction, unspecified
0.033 0.967 0.000
E31.8 Other polyglandular dysfunction
0.033 0.967 0.000
E31.1 Polyglandular hyperfunction
0.033 0.967 0.000
E31.0 Autoimmune polyglandular failure
0.033 0.967 0.000
E32.9 Disease of thymus, unspecified
0.033 0.967 0.000
E32.8 Other diseases of thymus
0.033 0.967 0.000
E32.1 Abscess of thymus
0.033 0.967 0.000
E32.0 Persistent hyperplasia of thymus
0.033 0.967 0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.033 0.967 0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.033 0.967 0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.033 0.967 0.000
M35.0 Sicca syndrome [Sjogren]
0.032 0.968 0.000
C44.3 Skin of other and unspecified parts of face
0.000 0.969 0.031
M48.86 Other specified spondylopathies (Lumbar region)
0.029 0.971 0.000
E23 Hypofunction and other disorders of pituitary gland
0.029 0.971 0.000
M48.55 Collapsed vertebra, not elsewhere classified (Thoracolumbar region)
0.029 0.971 0.000
M48.9 Spondylopathy, unspecified
0.028 0.971 0.000
E28.9 Ovarian dysfunction, unspecified
0.028 0.972 0.000
E28.8 Other ovarian dysfunction
0.028 0.972 0.000
E28.1 Androgen excess
0.028 0.972 0.000
E28.0 Oestrogen excess
0.028 0.972 0.000
E24.2 Drug-induced Cushing's syndrome
0.028 0.972 0.000
E66.0 Obesity due to excess calories
0.027 0.973 0.000
M48.58 Collapsed vertebra, not elsewhere classified (Sacral and sacrococcygeal region)
0.027 0.973 0.000
M48.57 Collapsed vertebra, not elsewhere classified (Lumbosacral region)
0.027 0.973 0.000
M48.53 Collapsed vertebra, not elsewhere classified (Cervicothoracic region)
0.027 0.973 0.000
M48.52 Collapsed vertebra, not elsewhere classified (Cervical region)
0.027 0.973 0.000
M48.51 Collapsed vertebra, not elsewhere classified (Occipito-atlanto-axial region)
0.027 0.973 0.000
E27 Other disorders of adrenal gland
0.027 0.973 0.000
E24.8 Other Cushing's syndrome
0.027 0.973 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.027 0.973 0.000
E24.3 Ectopic ACTH syndrome
0.027 0.973 0.000
E24.1 Nelson's syndrome
0.027 0.973 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.027 0.973 0.000
E24.0 Pituitary-dependent Cushing's disease
0.026 0.973 0.000
M48.59 Collapsed vertebra, not elsewhere classified (Site unspecified)
0.026 0.974 0.000
M48.82 Other specified spondylopathies (Cervical region)
0.026 0.974 0.000
M48.89 Other specified spondylopathies (Site unspecified)
0.026 0.974 0.000
M48.88 Other specified spondylopathies (Sacral and sacrococcygeal region)
0.026 0.974 0.000
M48.85 Other specified spondylopathies (Thoracolumbar region)
0.026 0.974 0.000
M48.84 Other specified spondylopathies (Thoracic region)
0.026 0.974 0.000
M48.83 Other specified spondylopathies (Cervicothoracic region)
0.026 0.974 0.000
M48.81 Other specified spondylopathies (Occipito-atlanto-axial region)
0.026 0.974 0.000
M48.80 Other specified spondylopathies (Multiple sites in spine)
0.026 0.974 0.000
M48.87 Other specified spondylopathies (Lumbosacral region)
0.026 0.974 0.000
E28.2 Polycystic ovarian syndrome
0.026 0.974 0.000
E66.1 Drug-induced obesity
0.025 0.975 0.000
E28.3 Primary ovarian failure
0.025 0.975 0.000
E29.9 Testicular dysfunction, unspecified
0.024 0.975 0.000
E29.8 Other testicular dysfunction
0.024 0.975 0.000
E29.0 Testicular hyperfunction
0.024 0.975 0.000
M48.19 Ankylosing hyperostosis [Forestier] (Site unspecified)
0.024 0.976 0.000
M48.18 Ankylosing hyperostosis [Forestier] (Sacral and sacrococcygeal region)
0.024 0.976 0.000
M48.17 Ankylosing hyperostosis [Forestier] (Lumbosacral region)
0.024 0.976 0.000
M48.16 Ankylosing hyperostosis [Forestier] (Lumbar region)
0.024 0.976 0.000
M48.15 Ankylosing hyperostosis [Forestier] (Thoracolumbar region)
0.024 0.976 0.000
M48.14 Ankylosing hyperostosis [Forestier] (Thoracic region)
0.024 0.976 0.000
M48.13 Ankylosing hyperostosis [Forestier] (Cervicothoracic region)
0.024 0.976 0.000
M48.12 Ankylosing hyperostosis [Forestier] (Cervical region)
0.024 0.976 0.000
M48.11 Ankylosing hyperostosis [Forestier] (Occipito-atlanto-axial region)
0.024 0.976 0.000
M48.10 Ankylosing hyperostosis [Forestier] (Multiple sites in spine)
0.024 0.976 0.000
M48.29 Kissing spine (Site unspecified)
0.024 0.976 0.000
M48.28 Kissing spine (Sacral and sacrococcygeal region)
0.024 0.976 0.000
M48.27 Kissing spine (Lumbosacral region)
0.024 0.976 0.000
M48.26 Kissing spine (Lumbar region)
0.024 0.976 0.000
M48.25 Kissing spine (Thoracolumbar region)
0.024 0.976 0.000
M48.24 Kissing spine (Thoracic region)
0.024 0.976 0.000
M48.23 Kissing spine (Cervicothoracic region)
0.024 0.976 0.000
M48.22 Kissing spine (Cervical region)
0.024 0.976 0.000
M48.21 Kissing spine (Occipito-atlanto-axial region)
0.024 0.976 0.000
M48.20 Kissing spine (Multiple sites in spine)
0.024 0.976 0.000
M48.39 Traumatic spondylopathy (Site unspecified)
0.024 0.976 0.000
M48.38 Traumatic spondylopathy (Sacral and sacrococcygeal region)
0.024 0.976 0.000
M48.37 Traumatic spondylopathy (Lumbosacral region)
0.024 0.976 0.000
M48.36 Traumatic spondylopathy (Lumbar region)
0.024 0.976 0.000
M48.35 Traumatic spondylopathy (Thoracolumbar region)
0.024 0.976 0.000
M48.34 Traumatic spondylopathy (Thoracic region)
0.024 0.976 0.000
M48.33 Traumatic spondylopathy (Cervicothoracic region)
0.024 0.976 0.000
M48.32 Traumatic spondylopathy (Cervical region)
0.024 0.976 0.000
M48.31 Traumatic spondylopathy (Occipito-atlanto-axial region)
0.024 0.976 0.000
M48.30 Traumatic spondylopathy (Multiple sites in spine)
0.024 0.976 0.000
M48.49 Fatigue fracture of vertebra (Site unspecified)
0.024 0.976 0.000
M48.48 Fatigue fracture of vertebra (Sacral and sacrococcygeal region)
0.024 0.976 0.000
M48.47 Fatigue fracture of vertebra (Lumbosacral region)
0.024 0.976 0.000
M48.46 Fatigue fracture of vertebra (Lumbar region)
0.024 0.976 0.000
M48.45 Fatigue fracture of vertebra (Thoracolumbar region)
0.024 0.976 0.000
M48.44 Fatigue fracture of vertebra (Thoracic region)
0.024 0.976 0.000
M48.43 Fatigue fracture of vertebra (Cervicothoracic region)
0.024 0.976 0.000
M48.42 Fatigue fracture of vertebra (Cervical region)
0.024 0.976 0.000
M48.41 Fatigue fracture of vertebra (Occipito-atlanto-axial region)
0.024 0.976 0.000
M48.40 Fatigue fracture of vertebra (Multiple sites in spine)
0.024 0.976 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.024 0.976 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.023 0.977 0.000
E22 Hyperfunction of pituitary gland
0.023 0.977 0.000
M48.56 Collapsed vertebra, not elsewhere classified (Lumbar region)
0.023 0.977 0.000
M48.92 Spondylopathy, unspecified (Cervical region)
0.022 0.978 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.021 0.979 0.000
E21.4 Other specified disorders of parathyroid gland
0.021 0.979 0.000
E23.7 Disorder of pituitary gland, unspecified
0.021 0.979 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.021 0.979 0.000
E23.1 Drug-induced hypopituitarism
0.021 0.979 0.000
M48.98 Spondylopathy, unspecified (Sacral and sacrococcygeal region)
0.020 0.979 0.000
M48.97 Spondylopathy, unspecified (Lumbosacral region)
0.020 0.979 0.000
M48.95 Spondylopathy, unspecified (Thoracolumbar region)
0.020 0.979 0.000
M48.94 Spondylopathy, unspecified (Thoracic region)
0.020 0.979 0.000
M48.93 Spondylopathy, unspecified (Cervicothoracic region)
0.020 0.979 0.000
M48.91 Spondylopathy, unspecified (Occipito-atlanto-axial region)
0.020 0.979 0.000
M48.90 Spondylopathy, unspecified (Multiple sites in spine)
0.020 0.979 0.000
E23.6 Other disorders of pituitary gland
0.020 0.980 0.000
M48.50 Collapsed vertebra, not elsewhere classified (Multiple sites in spine)
0.020 0.980 0.000
E21.2 Other hyperparathyroidism
0.020 0.980 0.000
E27.5 Adrenomedullary hyperfunction
0.019 0.980 0.000
E27.0 Other adrenocortical overactivity
0.019 0.980 0.000
E23.2 Diabetes insipidus
0.019 0.981 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.019 0.981 0.000
M48.96 Spondylopathy, unspecified (Lumbar region)
0.018 0.981 0.000
E27.1 Primary adrenocortical insufficiency
0.018 0.982 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.018 0.982 0.000
M48.99 Spondylopathy, unspecified (Site unspecified)
0.017 0.983 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.016 0.983 0.000
E22.8 Other hyperfunction of pituitary gland
0.016 0.983 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.017 0.983 0.000
E24.9 Cushing's syndrome, unspecified
0.016 0.984 0.000
E27.9 Disorder of adrenal gland, unspecified
0.016 0.984 0.000
D36 Benign neoplasm of other and unspecified sites
0.000 0.985 0.015
E22.0 Acromegaly and pituitary gigantism
0.015 0.985 0.000
E27.2 Addisonian crisis
0.015 0.985 0.000
E27.8 Other specified disorders of adrenal gland
0.013 0.987 0.000
C44.0 Skin of lip
0.000 0.987 0.013
E29.1 Testicular hypofunction
0.012 0.988 0.000
D36.7 Other specified sites
0.000 0.988 0.012
E22.1 Hyperprolactinaemia
0.012 0.988 0.000
E21.3 Hyperparathyroidism, unspecified
0.012 0.988 0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level
0.011 0.989 0.000
D36.9 Benign neoplasm of unspecified site
0.000 0.989 0.011
C44 Other malignant neoplasms of skin
0.000 0.990 0.010
M35 Other systemic involvement of connective tissue
0.010 0.990 0.000
E23.0 Hypopituitarism
0.009 0.991 0.000
C44.4 Skin of scalp and neck
0.000 0.991 0.009
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.008 0.991 0.000
D36.0 Lymph nodes
0.000 0.992 0.008
M35.7 Hypermobility syndrome
0.008 0.992 0.000
M71.26 Synovial cyst of popliteal space [Baker]-Lower Leg
0.008 0.992 0.000
J33.0 Polyp of nasal cavity
0.008 0.992 0.000
M35.2 Behcet's disease
0.008 0.992 0.000
C43.6 Malignant melanoma of upper limb, including shoulder
0.000 0.993 0.007
C44.1 Skin of eyelid, including canthus
0.000 0.993 0.007
C44.8 Overlapping lesion of skin
0.000 0.993 0.007
M35.1 Other overlap syndromes
0.007 0.993 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.007 0.993 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.007 0.993 0.000
M35.5 Multifocal fibrosclerosis
0.007 0.993 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.007 0.993 0.000
K75.4 Autoimmune hepatitis
0.007 0.993 0.000
N73.6 Female pelvic peritoneal adhesions
0.000 0.993 0.007
C43-C44 Melanoma and other malignant neoplasms of skin
0.000 0.993 0.007
C43.7 Malignant melanoma of lower limb, including hip
0.000 0.994 0.006
C43 Malignant melanoma of skin
0.000 0.994 0.006
M35.8 Other specified systemic involvement of connective tissue
0.006 0.994 0.000
J33.9 Nasal polyp, unspecified
0.006 0.994 0.000
K75.8 Other specified inflammatory liver diseases
0.006 0.994 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.006 0.994 0.000
K75 Other inflammatory liver diseases
0.006 0.994 0.000
J33 Nasal polyp
0.006 0.994 0.000
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified
0.005 0.995 0.000
K75.0 Abscess of liver
0.005 0.995 0.000
C43.9 Malignant melanoma of skin, unspecified
0.000 0.995 0.005
C43.1 Malignant melanoma of eyelid, including canthus
0.000 0.995 0.005
F33.9 Recurrent depressive disorder, unspecified
0.000 0.995 0.005
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level
0.005 0.995 0.000
C15.5 Lower third of oesophagus
0.000 0.995 0.005
C43.8 Overlapping malignant melanoma of skin
0.000 0.995 0.005
C43.0 Malignant melanoma of lip
0.000 0.995 0.005
M25.85 Other specified joint disorders (Pelvic region and thigh)
0.005 0.995 0.000
C44.9 Malignant neoplasm of skin, unspecified
0.000 0.995 0.005
I51.7 Cardiomegaly
0.005 0.995 0.000
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level
0.005 0.995 0.000
M25.8 Other specified joint disorders
0.005 0.995 0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level
0.005 0.995 0.000
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level
0.005 0.995 0.000
M25.88 Other specified joint disorders (Other)
0.004 0.995 0.000
M71.2 Synovial cyst of popliteal space [Baker]
0.004 0.995 0.000
M25.81 Other specified joint disorders (Shoulder region)
0.004 0.996 0.000
D47.3 Essential (haemorrhagic) thrombocythaemia
0.004 0.996 0.000
E21.0 Primary hyperparathyroidism
0.004 0.996 0.000
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level
0.004 0.996 0.000
K75.2 Nonspecific reactive hepatitis
0.004 0.996 0.000
K75.1 Phlebitis of portal vein
0.004 0.996 0.000
C43.2 Malignant melanoma of ear and external auricular canal
0.000 0.996 0.004
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level
0.004 0.996 0.000
S66.9 Injury of unspecified muscle and tendon at wrist and hand level
0.004 0.996 0.000
S62.00 Fracture of navicular [scaphoid] bone of hand (closed)
0.004 0.996 0.000
C15.9 Oesophagus, unspecified
0.000 0.996 0.004
C15 Malignant neoplasm of oesophagus
0.000 0.996 0.004
K75.3 Granulomatous hepatitis, not elsewhere classified
0.004 0.996 0.000
M25.86 Other specified joint disorders (Lower leg)
0.004 0.996 0.000
J33.8 Other polyp of sinus
0.004 0.996 0.000
M45-M49 Spondylopathies
0.004 0.996 0.000
M25.84 Other specified joint disorders (Hand)
0.004 0.996 0.000
T92.0 Sequelae of open wound of upper limb
0.004 0.996 0.000
K04.7 Periapical abscess without sinus
0.000 0.996 0.004
S32.00 Fracture of lumbar vertebra (closed)
0.004 0.996 0.000
S66.8 Injury of other muscles and tendons at wrist and hand level
0.004 0.996 0.000
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified
0.004 0.996 0.000
M25.89 Other specified joint disorders (Site unspecified)
0.003 0.996 0.000
M25.82 Other specified joint disorders (Upper arm)
0.003 0.996 0.000
M25.80 Other specified joint disorders (Multiple sites)
0.003 0.996 0.000
J33.1 Polypoid sinus degeneration
0.003 0.996 0.000
C43.4 Malignant melanoma of scalp and neck
0.000 0.996 0.003
M25.83 Other specified joint disorders (Forearm)
0.003 0.996 0.000
N73 Other female pelvic inflammatory diseases
0.000 0.996 0.004
M71.29 Synovial cyst of popliteal space [Baker]-Site unspec
0.003 0.996 0.000
M71.28 Synovial cyst of popliteal space [Baker]-Other
0.003 0.996 0.000
M71.27 Synovial cyst of popliteal space [Baker]-Ankle/Foot
0.003 0.996 0.000
M71.25 Synovial cyst of popliteal space [Baker]-Pelvic/Thigh
0.003 0.996 0.000
M71.24 Synovial cyst of popliteal space [Baker]-Hand
0.003 0.996 0.000
M71.23 Synovial cyst of popliteal space [Baker]-Forearm
0.003 0.996 0.000
M71.22 Synovial cyst of popliteal space [Baker]-Upper arm
0.003 0.996 0.000
M71.21 Synovial cyst of popliteal space [Baker]-Shldr region
0.003 0.996 0.000
M71.20 Synovial cyst of popliteal space [Baker]-Mult sites
0.003 0.996 0.000
C15.4 Middle third of oesophagus
0.000 0.996 0.003
F22.0 Delusional disorder
0.003 0.996 0.000
N73.5 Female pelvic peritonitis, unspecified
0.000 0.997 0.003
N80.8 Other endometriosis
0.003 0.997 0.000
E70-E90 Metabolic disorders
0.003 0.997 0.000
G82.1 Spastic paraplegia
0.000 0.997 0.003
C15.3 Upper third of oesophagus
0.000 0.997 0.003
J10.1 Influenza with other respiratory manifestations, influenza virus identified
0.000 0.997 0.003
C15.0 Cervical part of oesophagus
0.000 0.997 0.003
N70.1 Chronic salpingitis and oophoritis
0.000 0.997 0.003
K75.9 Inflammatory liver disease, unspecified
0.003 0.997 0.000
M25.87 Other specified joint disorders (Ankle and foot)
0.003 0.997 0.000
C15.8 Overlapping lesion of oesophagus
0.000 0.997 0.003
C15.2 Abdominal part of oesophagus
0.000 0.997 0.003
C15.1 Thoracic part of oesophagus
0.000 0.997 0.003
F40.2 Specific (isolated) phobias
0.003 0.997 0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level
0.003 0.997 0.000
E88 Other metabolic disorders
0.003 0.997 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.003 0.997 0.000
E88.9 Metabolic disorder, unspecified
0.003 0.997 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.003 0.997 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.003 0.997 0.000
G06.1 Intraspinal abscess and granuloma
0.003 0.997 0.000
N73.1 Chronic parametritis and pelvic cellulitis
0.000 0.997 0.003
E88.3 Tumour lysis syndrome
0.003 0.997 0.000
G82.2 Paraplegia, unspecified
0.000 0.997 0.003
C81.9 Hodgkin's disease, unspecified
0.000 0.997 0.003
G63.2 Diabetic polyneuropathy
0.003 0.997 0.000
C81.1 Nodular sclerosis
0.000 0.997 0.003
N73.0 Acute parametritis and pelvic cellulitis
0.000 0.997 0.003
N39.8 Other specified disorders of urinary system
0.000 0.997 0.003
N73.4 Female chronic pelvic peritonitis
0.000 0.997 0.003

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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