TreeWAS – Variant ID: rs910873

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
C44.6 Skin of upper limb, including shoulder	1.000	0.000
C44.5 Skin of trunk	1.000	0.000
C44.4 Skin of scalp and neck	1.000	0.000
C44.3 Skin of other and unspecified parts of face	1.000	0.000
L57.0 Actinic keratosis	1.000	0.000
C44 Other malignant neoplasms of skin	1.000	0.000
C43 Malignant melanoma of skin	1.000	0.000
C43-C44 Melanoma and other malignant neoplasms of skin	1.000	0.000
L80-L99 Other disorders of the skin and subcutaneous tissue	1.000	0.000
Chapter II Neoplasms	1.000	0.000
C43.5 Malignant melanoma of trunk	1.000	0.000
C44.1 Skin of eyelid, including canthus	1.000	0.000
Z85.8 Personal history of malignant neoplasms of other organs and systems	1.000	0.000
L57 Skin changes due to chronic exposure to nonionising radiation	1.000	0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	1.000	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	1.000	0.000
C43.6 Malignant melanoma of upper limb, including shoulder	1.000	0.000
L90.5 Scar conditions and fibrosis of skin	0.999	0.001
L90 Atrophic disorders of skin	0.999	0.001
L85 Other epidermal thickening	0.998	0.002
L81 Other disorders of pigmentation	0.997	0.003
M20 Acquired deformities of fingers and toes	0.997	0.003
C44.2 Skin of ear and external auricular canal	0.995	0.005
M20-M25 Other joint disorders	0.995	0.005
L81.4 Other melanin hyperpigmentation	0.994	0.006
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.992	0.008
M20.1 Hallux valgus (acquired)	0.990	0.010
D00-D09 In situ neoplasms	0.989	0.011
M80-M85 Disorders of bone density and structure	0.986	0.014
L85.9 Epidermal thickening, unspecified	0.984	0.016
C44.7 Skin of lower limb, including hip	0.982	0.018
M20.4 Other hammer toe(s) (acquired)	0.982	0.018
C64-C68 Malignant neoplasms of urinary tract	0.980	0.020
D03 Melanoma in situ	0.978	0.022
# Top node	0.970	0.030
L85.8 Other specified epidermal thickening	0.967	0.033
M80 Osteoporosis with pathological fracture	0.964	0.036
C43.4 Malignant melanoma of scalp and neck	0.964	0.036
C50-C50 Malignant neoplasm of breast	0.953	0.047
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.947	0.053
C44.0 Skin of lip	0.945	0.055
N40 Hyperplasia of prostate	0.943	0.057
C67 Malignant neoplasm of bladder	0.941	0.059
D03.5 Melanoma in situ of trunk	0.941	0.059
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.941	0.059
M84 Disorders of continuity of bone	0.939	0.061
M24 Other specific joint derangements	0.938	0.062
M80.9 Unspecified osteoporosis with pathological fracture	0.937	0.063
M20.6 Acquired deformity of toe(s), unspecified	0.929	0.071
C50 Malignant neoplasm of breast	0.919	0.081
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.915	0.085
D37-D48 Neoplasms of uncertain or unknown behaviour	0.915	0.085
C90 Multiple myeloma and malignant plasma cell neoplasms	0.910	0.090
M84.1 Nonunion of fracture [pseudarthrosis]	0.906	0.094
Q38-Q45 Other congenital malformations of the digestive system	0.903	0.097
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.899	0.101
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.897	0.103
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.896	0.104
C71 Malignant neoplasm of brain	0.895	0.105
C90.0 Multiple myeloma	0.893	0.107
D46 Myelodysplastic syndromes	0.887	0.113
M40-M43 Deforming dorsopathies	0.887	0.113
M21 Other acquired deformities of limbs	0.886	0.114
Chapter VII Diseases of the eye and adnexa	0.885	0.115
C43.9 Malignant melanoma of skin, unspecified	0.884	0.116
M60-M63 Disorders of muscles	0.882	0.118
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified	0.878	0.122
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.877	0.123
D03.6 Melanoma in situ of upper limb, including shoulder	0.869	0.131
M20.0 Deformity of finger(s)	0.868	0.132
C43.7 Malignant melanoma of lower limb, including hip	0.866	0.134
C66 Malignant neoplasm of ureter	0.865	0.135
Q38 Other congenital malformations of tongue, mouth and pharynx	0.864	0.135
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.858	0.142
H04 Disorders of lachrymal system	0.855	0.145
H30-H36 Disorders of choroid and retina	0.855	0.145
D46.9 Myelodysplastic syndrome, unspecified	0.854	0.146
C44.9 Malignant neoplasm of skin, unspecified	0.852	0.148
H34 Retinal vascular occlusions	0.849	0.151
C50.2 Upper-inner quadrant of breast	0.847	0.153
C50.3 Lower-inner quadrant of breast	0.847	0.153
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.843	0.157
M24.2 Disorder of ligament	0.840	0.160
L81.8 Other specified disorders of pigmentation	0.840	0.160
D04 Carcinoma in situ of skin	0.839	0.161
H02 Other disorders of eyelid	0.839	0.161
Q38.7 Pharyngeal pouch	0.837	0.163
C67.6 Ureteric orifice	0.836	0.164
C71.9 Brain, unspecified	0.835	0.165
M20.5 Other deformities of toe(s) (acquired)	0.833	0.167
M86-M90 Other osteopathies	0.833	0.167
M32 Systemic lupus erythematosus	0.830	0.170
C65 Malignant neoplasm of renal pelvis	0.829	0.171
H02.1 Ectropion of eyelid	0.829	0.171
H34.2 Other retinal artery occlusions	0.823	0.177
H04.5 Stenosis and insufficiency of lachrymal passages	0.821	0.179
L57.8 Other skin changes due to chronic exposure to nonionising radiation	0.819	0.181
C90.2 Plasmacytoma, extramedullary	0.815	0.185
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.813	0.187
D07 Carcinoma in situ of other and unspecified genital organs	0.812	0.188
Q66 Congenital deformities of feet	0.811	0.189
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified	0.811	0.189
L98.4 Chronic ulcer of skin, not elsewhere classified	0.809	0.191
Q50-Q56 Congenital malformations of genital organs	0.807	0.193
D03.3 Melanoma in situ of other and unspecified parts of face	0.802	0.198
M30 Polyarteritis nodosa and related conditions	0.801	0.199
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.796	0.204
M24.4 Recurrent dislocation and subluxation of joint	0.796	0.204
C81 Hodgkin's disease	0.796	0.204
H34.8 Other retinal vascular occlusions	0.796	0.204
M62 Other disorders of muscle	0.795	0.205
C71.0 Cerebrum, except lobes and ventricles	0.795	0.205
H04.2 Epiphora	0.795	0.205
M80.0 Postmenopausal osteoporosis with pathological fracture	0.794	0.206
D03.2 Melanoma in situ of ear and external auricular canal	0.788	0.212
M00-M03 Infectious arthropathies	0.786	0.214
L94 Other localised connective tissue disorders	0.783	0.217
C67.8 Overlapping lesion of bladder	0.780	0.220
M24.8 Other specific joint derangements, not elsewhere classified	0.779	0.221
C43.3 Malignant melanoma of other and unspecified parts of face	0.778	0.222
L81.2 Freckles	0.775	0.225
C43.1 Malignant melanoma of eyelid, including canthus	0.773	0.227
C43.2 Malignant melanoma of ear and external auricular canal	0.773	0.227
M24.26 Disorder of ligament (Lower leg)	0.771	0.229
C67.4 Posterior wall of bladder	0.771	0.229
D03.4 Melanoma in situ of scalp and neck	0.769	0.231
C40-C41 Malignant neoplasms of bone and articular cartilage	0.768	0.232
M40 Kyphosis and lordosis	0.761	0.239
M81 Osteoporosis without pathological fracture	0.758	0.242
M84.2 Delayed union of fracture	0.752	0.248
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.752	0.248
L56 Other acute skin changes due to ultraviolet radiation	0.751	0.249
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.750	0.249
C69 Malignant neoplasm of eye and adnexa	0.749	0.251
D09 Carcinoma in situ of other and unspecified sites	0.748	0.252
C67.9 Bladder, unspecified	0.748	0.252
L85.1 Acquired keratosis [keratoderma] palmaris et plantaris	0.745	0.254
C13 Malignant neoplasm of hypopharynx	0.745	0.255
C67.0 Trigone of bladder	0.745	0.255
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.744	0.256
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.743	0.257
C50.8 Overlapping lesion of breast	0.741	0.259
Q76 Congenital malformations of spine and bony thorax	0.741	0.259
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.740	0.260
L10-L14 Bullous disorders	0.738	0.262
M21.6 Other acquired deformities of ankle and foot	0.738	0.262
C50.5 Lower-outer quadrant of breast	0.738	0.262
L83 Acanthosis nigricans	0.737	0.263
C84 Peripheral and cutaneous T-cell lymphomas	0.735	0.265
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.735	0.265
C04 Malignant neoplasm of floor of mouth	0.734	0.266
M25 Other joint disorders, not elsewhere classified	0.734	0.266
D05 Carcinoma in situ of breast	0.731	0.269
H02.0 Entropion and trichiasis of eyelid	0.730	0.270
M21.3 Wrist or foot drop (acquired)	0.729	0.270
Q39 Congenital malformations of oesophagus	0.729	0.271
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.728	0.272
M24.6 Ankylosis of joint	0.728	0.272
C90.3 Solitary plasmacytoma	0.725	0.275
H35 Other retinal disorders	0.725	0.275
L98.1 Factitial dermatitis	0.724	0.276
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere	0.724	0.276
M84.4 Pathological fracture, not elsewhere classified	0.723	0.276
C67.5 Bladder neck	0.723	0.277
L89 Decubitus ulcer	0.721	0.279
L50-L54 Urticaria and erythema	0.720	0.280
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx	0.719	0.281
D46.4 Refractory anaemia, unspecified	0.718	0.282
C43.8 Overlapping malignant melanoma of skin	0.717	0.283
C43.0 Malignant melanoma of lip	0.717	0.283
C44.8 Overlapping lesion of skin	0.717	0.283
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere	0.717	0.283
L87 Transepidermal elimination disorders	0.717	0.283
L88 Pyoderma gangrenosum	0.717	0.283
L86 Keratoderma in diseases classified elsewhere	0.717	0.283
L57.5 Actinic granuloma	0.717	0.283
L57.3 Poikiloderma of Civatte	0.717	0.283
L57.2 Cutis rhomboidalis nuchae	0.717	0.283
L57.1 Actinic reticuloid	0.717	0.283
L59 Other disorders of skin and subcutaneous tissue related to radiation	0.717	0.283
L58 Radiodermatitis	0.717	0.283
L55 Sunburn	0.717	0.283
L90.9 Atrophic disorder of skin, unspecified	0.717	0.283
L90.8 Other atrophic disorders of skin	0.717	0.283
L90.6 Striae atrophicae	0.717	0.283
L90.4 Acrodermatitis chronica atrophicans	0.717	0.283
L90.3 Atrophoderma of Pasini and Pierini	0.717	0.283
L90.2 Anetoderma of Jadassohn-Pellizzari	0.717	0.283
L90.1 Anetoderma of Schweninger-Buzzi	0.717	0.283
L85.3 Xerosis cutis	0.715	0.284
L85.2 Keratosis punctata (palmaris et plantaris)	0.715	0.284
L85.0 Acquired ichthyosis	0.715	0.284
L81.7 Pigmented purpuric dermatosis	0.715	0.285
L81.6 Other disorders of diminished melanin formation	0.715	0.285
L81.5 Leukoderma, not elsewhere classified	0.715	0.285
L81.3 Cafe au lait spots	0.715	0.285
L81.1 Chloasma	0.715	0.285
L81.0 Postinflammatory hyperpigmentation	0.715	0.285
L93 Lupus erythematosus	0.714	0.285
D41.4 Bladder	0.714	0.286
D07.5 Prostate	0.714	0.286
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.713	0.287
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.712	0.287
M62.8 Other specified disorders of muscle	0.712	0.288
C81.1 Nodular sclerosis	0.712	0.288
M32.1 Systemic lupus erythematosus with organ or system involvement	0.712	0.288
M24.1 Other articular cartilage disorders	0.712	0.288
M21.4 Flat foot [pes planus] (acquired)	0.710	0.290
D01 Carcinoma in situ of other and unspecified digestive organs	0.709	0.291
M41 Scoliosis	0.709	0.291
M83 Adult osteomalacia	0.707	0.293
M80.5 Idiopathic osteoporosis with pathological fracture	0.705	0.295
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.705	0.295
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.704	0.295
M81.4 Drug-induced osteoporosis	0.704	0.296
C68 Malignant neoplasm of other and unspecified urinary organs	0.703	0.297
H04.4 Chronic inflammation of lachrymal passages	0.703	0.297
M87 Osteonecrosis	0.702	0.298
D03.9 Melanoma in situ, unspecified	0.701	0.298
D03.8 Melanoma in situ of other sites	0.701	0.298
D03.1 Melanoma in situ of eyelid, including canthus	0.701	0.298
D03.0 Melanoma in situ of lip	0.701	0.298
M65-M68 Disorders of synovium and tendon	0.701	0.299
C50.0 Nipple and areola	0.699	0.301
D41.0 Kidney	0.699	0.301
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.699	0.301
C08 Malignant neoplasm of other and unspecified major salivary glands	0.697	0.303
L98.9 Disorder of skin and subcutaneous tissue, unspecified	0.697	0.303
C50.1 Central portion of breast	0.696	0.304
M45-M49 Spondylopathies	0.696	0.304
Chapter XVI Certain conditions originating in the perinatal period	0.695	0.304
M85 Other disorders of bone density and structure	0.694	0.306
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.691	0.308
C10 Malignant neoplasm of oropharynx	0.691	0.309
M80.8 Other osteoporosis with pathological fracture	0.691	0.309
M80.4 Drug-induced osteoporosis with pathological fracture	0.691	0.309
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.691	0.309
M80.2 Osteoporosis of disuse with pathological fracture	0.691	0.309
Q66.8 Other congenital deformities of feet	0.689	0.310
C06 Malignant neoplasm of other and unspecified parts of mouth	0.688	0.312
M21.1 Varus deformity, not elsewhere classified	0.688	0.312
M21.2 Flexion deformity	0.686	0.314
C12 Malignant neoplasm of pyriform sinus	0.686	0.314
D41.1 Renal pelvis	0.686	0.314
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.685	0.315
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.680	0.320
H01 Other inflammation of eyelid	0.679	0.321
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.679	0.321
C70 Malignant neoplasm of meninges	0.679	0.321
M43 Other deforming dorsopathies	0.677	0.323
C50.6 Axillary tail of breast	0.676	0.323
Q80-Q89 Other congenital malformations	0.675	0.324
C67.3 Anterior wall of bladder	0.675	0.325
C67.7 Urachus	0.675	0.325
Q35-Q37 Cleft lip and cleft palate	0.675	0.325
Q30-Q34 Congenital malformations of the respiratory system	0.675	0.325
C11 Malignant neoplasm of nasopharynx	0.675	0.325
D04.2 Skin of ear and external auricular canal	0.674	0.326
M84.9 Disorder of continuity of bone, unspecified	0.673	0.327
M84.8 Other disorders of continuity of bone	0.673	0.327
M84.3 Stress fracture, not elsewhere classified	0.673	0.327
M24.9 Joint derangement, unspecified	0.673	0.327
M24.7 Protrusio acetabuli	0.673	0.327
D46.2 Refractory anaemia with excess of blasts	0.672	0.328
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.672	0.328
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.672	0.328
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.672	0.328
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.672	0.328
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.672	0.328
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.672	0.328
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.672	0.328
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)	0.672	0.328
M40.2 Other and unspecified kyphosis	0.671	0.329
N40-N51 Diseases of male genital organs	0.670	0.330
Q51 Congenital malformations of uterus and cervix	0.668	0.332
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.668	0.332
D05.0 Lobular carcinoma in situ	0.667	0.333
H53-H54 Visual disturbances and blindness	0.666	0.334
D04.4 Skin of scalp and neck	0.666	0.334
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.665	0.335
H34.1 Central retinal artery occlusion	0.664	0.336
M24.23 Disorder of ligament (Forearm)	0.664	0.336
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.662	0.338
C71.4 Occipital lobe	0.662	0.338
M90 Osteopathies in diseases classified elsewhere	0.660	0.340
L94.2 Calcinosis cutis	0.658	0.342
H03 Disorders of eyelid in diseases classified elsewhere	0.658	0.342
M25.3 Other instability of joint	0.656	0.344
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.656	0.344
C94 Other leukaemias of specified cell type	0.656	0.344
C93 Monocytic leukaemia	0.656	0.344
C86 Other specified types of T/NK-cell lymphoma	0.656	0.344
D45 Polycythaemia vera	0.656	0.344
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.656	0.344
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.656	0.344
C95 Leukaemia of unspecified cell type	0.656	0.344
Q66.7 Pes cavus	0.656	0.344
Q43 Other congenital malformations of intestine	0.655	0.344
M60 Myositis	0.655	0.345
D02 Carcinoma in situ of middle ear and respiratory system	0.652	0.347
C90.1 Plasma cell leukaemia	0.652	0.348
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.650	0.350
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.650	0.350
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.650	0.350
N41 Inflammatory diseases of prostate	0.649	0.351
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.649	0.351
Q45 Other congenital malformations of digestive system	0.647	0.353
Q42 Congenital absence, atresia and stenosis of large intestine	0.647	0.353
Q41 Congenital absence, atresia and stenosis of small intestine	0.647	0.353
Q40 Other congenital malformations of upper alimentary tract	0.647	0.353
M91-M94 Chondropathies	0.646	0.354
M20.2 Hallux rigidus	0.645	0.355
C05 Malignant neoplasm of palate	0.645	0.355
C03 Malignant neoplasm of gum	0.645	0.355
C00 Malignant neoplasm of lip	0.645	0.355
M22 Disorders of patella	0.644	0.355
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)	0.644	0.356
Q78 Other osteochondrodysplasias	0.643	0.357
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.643	0.357
Q75 Other congenital malformations of skull and face bones	0.643	0.357
Q74 Other congenital malformations of limb(s)	0.643	0.357
Q73 Reduction defects of unspecified limb	0.643	0.357
Q72 Reduction defects of lower limb	0.643	0.357
Q71 Reduction defects of upper limb	0.643	0.357
Q70 Syndactyly	0.643	0.357
Q69 Polydactyly	0.643	0.357
Q68 Other congenital musculoskeletal deformities	0.643	0.357
M81.40 Drug-induced osteoporosis (Multiple sites)	0.642	0.358
C71.7 Brain stem	0.642	0.358
C71.6 Cerebellum	0.642	0.358
C71.5 Cerebral ventricle	0.642	0.358
C01 Malignant neoplasm of base of tongue	0.640	0.359
N41.1 Chronic prostatitis	0.640	0.360
H02.8 Other specified disorders of eyelid	0.640	0.360
C92 Myeloid leukaemia	0.640	0.360
Q66.2 Metatarsus varus	0.639	0.360
M88 Paget's disease of bone [osteitis deformans]	0.639	0.361
M00 Pyogenic arthritis	0.638	0.361
M48 Other spondylopathies	0.638	0.362
C67.2 Lateral wall of bladder	0.637	0.363
L57.4 Cutis laxa senilis	0.637	0.363
C71.3 Parietal lobe	0.637	0.363
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.636	0.363
H02.5 Other disorders affecting eyelid function	0.636	0.364
D46.7 Other myelodysplastic syndromes	0.636	0.364
D46.6 Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality	0.636	0.364
D46.5 Refractory anaemia with multi-lineage dysplasia	0.636	0.364
D46.3 Refractory anaemia with excess of blasts with transformation	0.636	0.364
D46.1 Refractory anaemia with sideroblasts	0.636	0.364
D46.0 Refractory anaemia without sideroblasts, so stated	0.636	0.364
M42 Spinal osteochondrosis	0.636	0.364
M21.9 Acquired deformity of limb, unspecified	0.636	0.364
M21.8 Other specified acquired deformities of limbs	0.636	0.364
M21.7 Unequal limb length (acquired)	0.636	0.364
C13.9 Hypopharynx, unspecified	0.634	0.365
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.633	0.367
M62.88 Other specified disorders of muscle (Other)	0.633	0.367
M63 Disorders of muscle in diseases classified elsewhere	0.632	0.368
M61 Calcification and ossification of muscle	0.632	0.368
H35.7 Separation of retinal layers	0.632	0.368
L60-L75 Disorders of skin appendages	0.631	0.369
M21.67 Other acquired deformities of ankle and foot-Ankle/foot	0.631	0.369
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.631	0.369
L98.7 Excessive and redundant skin and subcutaneous tissue	0.629	0.371
L98.6 Other infiltrative disorders of skin and subcutaneous tissue	0.629	0.371
L98.5 Mucinosis of skin	0.629	0.371
L98.3 Eosinophilic cellulitis [Wells]	0.629	0.371
L98.2 Febrile neutrophilic dermatosis [Sweet]	0.629	0.371
M23 Internal derangement of knee	0.628	0.372
Q79.6 Ehlers-Danlos syndrome	0.628	0.372
D09.1 Other and unspecified urinary organs	0.627	0.373
D04.3 Skin of other and unspecified parts of face	0.627	0.373
M62.6 Muscle strain	0.627	0.373
Q54 Hypospadias	0.626	0.373
D04.5 Skin of trunk	0.626	0.373
L95 Vasculitis limited to skin, not elsewhere classified	0.626	0.374
M48.5 Collapsed vertebra, not elsewhere classified	0.626	0.374
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.625	0.375
Chapter XIV Diseases of the genitourinary system	0.624	0.376
M67 Other disorders of synovium and tendon	0.623	0.377
D44.9 Endocrine gland, unspecified	0.622	0.378
D04.7 Skin of lower limb, including hip	0.622	0.378
M34 Systemic sclerosis	0.621	0.379
Q38.8 Other congenital malformations of pharynx	0.620	0.380
Q38.6 Other congenital malformations of mouth	0.620	0.380
Q38.5 Congenital malformations of palate, not elsewhere classified	0.620	0.380
Q38.4 Congenital malformations of salivary glands and ducts	0.620	0.380
Q38.3 Other congenital malformations of tongue	0.620	0.380
Q38.2 Macroglossia	0.620	0.380
Q38.1 Ankyloglossia	0.620	0.380
Q38.0 Congenital malformations of lips, not elsewhere classified	0.620	0.380
M84.26 Delayed union of fracture (Lower leg)	0.618	0.382
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.617	0.383
C04.9 Floor of mouth, unspecified	0.616	0.384
M24.37 Pathological dislocation and subluxation of joint, not elsewhere classified (Ankle and foot)	0.616	0.384
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)	0.616	0.384
C71.2 Temporal lobe	0.616	0.384
H06.2 Dysthyroid exophthalmos	0.614	0.386
L81.9 Disorder of pigmentation, unspecified	0.614	0.386
D43.2 Brain, unspecified	0.614	0.386
H04.6 Other changes in lachrymal passages	0.613	0.387
H04.0 Dacryoadenitis	0.613	0.387
H32 Chorioretinal disorders in diseases classified elsewhere	0.613	0.387
H30 Chorioretinal inflammation	0.613	0.387
L50 Urticaria	0.612	0.388
L89.0 Stage I decubitus ulcer and pressure area	0.612	0.388
M33 Dermatopolymyositis	0.611	0.389
H34.9 Retinal vascular occlusion, unspecified	0.609	0.391
H34.0 Transient retinal artery occlusion	0.609	0.391
Q39.4 Oesophageal web	0.608	0.392
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.608	0.392
M82 Osteoporosis in diseases classified elsewhere	0.607	0.393
D07.4 Penis	0.607	0.393
H53 Visual disturbances	0.606	0.394
M86 Osteomyelitis	0.605	0.395
D41.9 Urinary organ, unspecified	0.604	0.395
D41.7 Other urinary organs	0.604	0.395
D41.3 Urethra	0.604	0.395
D41.2 Ureter	0.604	0.395
C71.1 Frontal lobe	0.603	0.397
H02.9 Disorder of eyelid, unspecified	0.603	0.397
M24.29 Disorder of ligament (Site unspecified)	0.602	0.398
M24.28 Disorder of ligament (Other)	0.602	0.398
M24.25 Disorder of ligament (Pelvic region and thigh)	0.602	0.398
M24.22 Disorder of ligament (Upper arm)	0.602	0.398
M24.21 Disorder of ligament (Shoulder region)	0.602	0.398
M24.20 Disorder of ligament (Multiple sites)	0.602	0.398
D04.9 Skin, unspecified	0.602	0.398
D04.8 Skin of other sites	0.602	0.398
D04.1 Skin of eyelid, including canthus	0.602	0.398
D04.0 Skin of lip	0.602	0.398
H02.7 Other degenerative disorders of eyelid and periocular area	0.602	0.398
M25.7 Osteophyte	0.602	0.398
M40.24 Other and unspecified kyphosis (Thoracic region)	0.601	0.398
C41 Malignant neoplasm of bone and articular cartilage of other and unspecified sites	0.601	0.399
M24.5 Contracture of joint	0.599	0.401
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)	0.598	0.402
M32.9 Systemic lupus erythematosus, unspecified	0.595	0.405
M32.8 Other forms of systemic lupus erythematosus	0.595	0.405
M32.0 Drug-induced systemic lupus erythematosus	0.595	0.405
M84.42 Pathological fracture, not elsewhere classified (Upper arm)	0.594	0.406
M24.11 Other articular cartilage disorders (Shoulder region)	0.593	0.407
H02.2 Lagophthalmos	0.592	0.408
H43-H45 Disorders of vitreous body and globe	0.591	0.409
C14.0 Pharynx, unspecified	0.590	0.410
L98.0 Pyogenic granuloma	0.589	0.411
L91 Hypertrophic disorders of skin	0.586	0.414
H35.9 Retinal disorder, unspecified	0.585	0.415
C84.4 Peripheral T-cell lymphoma	0.585	0.415
M21.47 Flat foot [pes planus] (acquired)-Ankle/foot	0.583	0.417
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.583	0.417
D07.6 Other and unspecified male genital organs	0.582	0.418
D07.3 Other and unspecified female genital organs	0.582	0.418
D07.2 Vagina	0.582	0.418
D07.0 Endometrium	0.582	0.418
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.582	0.418
Q66.9 Congenital deformity of feet, unspecified	0.581	0.419
Q66.6 Other congenital valgus deformities of feet	0.581	0.419
Q66.5 Congenital pes planus	0.581	0.419
Q66.4 Talipes calcaneovalgus	0.581	0.419
Q66.3 Other congenital varus deformities of feet	0.581	0.419
Q66.1 Talipes calcaneovarus	0.581	0.419
Q66.0 Talipes equinovarus	0.581	0.419
C69.3 Choroid	0.581	0.419
M41.9 Scoliosis, unspecified	0.581	0.419
H35.5 Hereditary retinal dystrophy	0.580	0.420
M81.49 Drug-induced osteoporosis (Site unspecified)	0.580	0.420
M48.56 Collapsed vertebra, not elsewhere classified (Lumbar region)	0.579	0.421
Q56 Indeterminate sex and pseudohermaphroditism	0.579	0.421
Q55 Other congenital malformations of male genital organs	0.579	0.421
Q53 Undescended testicle	0.579	0.421
Q52 Other congenital malformations of female genitalia	0.579	0.421
M24.67 Ankylosis of joint (Ankle and foot)	0.577	0.423
C09 Malignant neoplasm of tonsil	0.576	0.424
C67.1 Dome of bladder	0.576	0.424
M25.0 Haemarthrosis	0.575	0.425
M30.8 Other conditions related to polyarteritis nodosa	0.574	0.425
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]	0.574	0.425
M30.2 Juvenile polyarteritis	0.574	0.425
M30.0 Polyarteritis nodosa	0.574	0.425
L80 Vitiligo	0.572	0.428
H04.8 Other disorders of lachrymal system	0.572	0.428
H04.9 Disorder of lachrymal system, unspecified	0.572	0.428
D43.0 Brain, supratentorial	0.571	0.429
L56.9 Acute skin change due to ultraviolet radiation, unspecified	0.571	0.429
M24.49 Recurrent dislocation and subluxation of joint (Site unspecified)	0.571	0.429
M24.48 Recurrent dislocation and subluxation of joint (Other)	0.571	0.429
M24.46 Recurrent dislocation and subluxation of joint (Lower leg)	0.571	0.429
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)	0.571	0.429
M24.44 Recurrent dislocation and subluxation of joint (Hand)	0.571	0.429
M24.43 Recurrent dislocation and subluxation of joint (Forearm)	0.571	0.429
M24.42 Recurrent dislocation and subluxation of joint (Upper arm)	0.571	0.429
M24.40 Recurrent dislocation and subluxation of joint (Multiple sites)	0.571	0.429
C81.7 Other Hodgkin's disease	0.570	0.429
C81.4 Lymphocyte-rich classical Hodgkin lymphoma	0.570	0.429
C81.3 Lymphocytic depletion	0.570	0.429
C81.2 Mixed cellularity	0.570	0.429
C81.0 Lymphocytic predominance	0.570	0.429
M62.9 Disorder of muscle, unspecified	0.570	0.430
M62.5 Muscle wasting and atrophy, not elsewhere classified	0.570	0.430

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations