TreeWAS – Variant ID: rs913455

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K90.0 Coeliac disease	1.000	0.000	0.000
E00-E07 Disorders of thyroid gland	1.000	0.000	0.000
M20-M25 Other joint disorders	1.000	0.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000	0.000
# Top node	1.000	0.000	0.000
E05.9 Thyrotoxicosis, unspecified	1.000	0.000	0.000
E10 Insulin-dependent diabetes mellitus	1.000	0.000	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	1.000	0.000	0.000
N40 Hyperplasia of prostate	0.000	0.000	1.000
N40-N51 Diseases of male genital organs	0.000	0.000	1.000
Chapter XIV Diseases of the genitourinary system	0.000	0.000	1.000
D64.9 Anaemia, unspecified	1.000	0.000	0.000
E05 Thyrotoxicosis [hyperthyroidism]	1.000	0.000	0.000
D60-D64 Aplastic and other anaemias	1.000	0.000	0.000
D64 Other anaemias	1.000	0.000	0.000
M05-M14 Inflammatory polyarthropathies	1.000	0.000	0.000
E10-E14 Diabetes mellitus	1.000	0.000	0.000
N30-N39 Other diseases of urinary system	0.000	0.000	1.000
N32 Other disorders of bladder	0.000	0.000	1.000
N20-N23 Urolithiasis	0.000	0.000	1.000
E10.9 Without complications	0.999	0.001	0.000
E83.1 Disorders of iron metabolism	0.000	0.001	0.999
N20 Calculus of kidney and ureter	0.000	0.001	0.999
M06 Other rheumatoid arthritis	0.999	0.001	0.000
E20-E35 Disorders of other endocrine glands	0.999	0.001	0.000
M06.9 Rheumatoid arthritis, unspecified	0.999	0.001	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.998	0.002	0.000
M25 Other joint disorders, not elsewhere classified	0.998	0.002	0.000
N32.0 Bladder-neck obstruction	0.000	0.002	0.998
E27 Other disorders of adrenal gland	0.997	0.003	0.000
N20.0 Calculus of kidney	0.000	0.003	0.997
E27.1 Primary adrenocortical insufficiency	0.995	0.005	0.000
E03 Other hypothyroidism	0.995	0.005	0.000
M25.7 Osteophyte	0.992	0.008	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.992	0.008	0.000
E03.9 Hypothyroidism, unspecified	0.992	0.008	0.000
E10.3 With ophthalmic complications	0.992	0.008	0.000
L20-L30 Dermatitis and eczema	0.985	0.015	0.000
N20.1 Calculus of ureter	0.000	0.019	0.981
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.979	0.021	0.000
N32.8 Other specified disorders of bladder	0.000	0.021	0.979
S90-S99 Injuries to the ankle and foot	0.976	0.024	0.000
M35 Other systemic involvement of connective tissue	0.975	0.025	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.974	0.026	0.000
M35.0 Sicca syndrome [Sjogren]	0.970	0.030	0.000
E70-E90 Metabolic disorders	0.969	0.031	0.000
N00-N08 Glomerular diseases	0.000	0.032	0.968
E83 Disorders of mineral metabolism	0.960	0.035	0.005
E16 Other disorders of pancreatic internal secretion	0.964	0.036	0.000
N42 Other disorders of prostate	0.000	0.039	0.961
M34 Systemic sclerosis	0.960	0.040	0.000
E83.5 Disorders of calcium metabolism	0.957	0.043	0.000
M15-M19 Arthrosis	0.955	0.045	0.000
M17 Gonarthrosis [arthrosis of knee]	0.952	0.048	0.000
Chapter V Mental and behavioural disorders	0.952	0.048	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.950	0.050	0.000
M17.0 Primary gonarthrosis, bilateral	0.948	0.052	0.000
T79-T79 Certain early complications of trauma	0.946	0.054	0.000
E16.2 Hypoglycaemia, unspecified	0.946	0.054	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.945	0.055	0.000
M25.77 Osteophyte (Ankle and foot)	0.943	0.057	0.000
M24 Other specific joint derangements	0.942	0.058	0.000
N02 Recurrent and persistent haematuria	0.000	0.062	0.938
N41 Inflammatory diseases of prostate	0.000	0.062	0.938
T66-T78 Other and unspecified effects of external causes	0.937	0.063	0.000
L50-L54 Urticaria and erythema	0.933	0.067	0.000
L30 Other dermatitis	0.930	0.070	0.000
K90 Intestinal malabsorption	0.929	0.071	0.000
L27 Dermatitis due to substances taken internally	0.928	0.072	0.000
D80-D89 Certain disorders involving the immune mechanism	0.927	0.073	0.000
M10 Gout	0.924	0.076	0.000
M65-M68 Disorders of synovium and tendon	0.923	0.077	0.000
M23 Internal derangement of knee	0.922	0.078	0.000
N32.3 Diverticulum of bladder	0.000	0.079	0.921
S92 Fracture of foot, except ankle	0.921	0.079	0.000
M25.9 Joint disorder, unspecified	0.919	0.081	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.917	0.083	0.000
M22 Disorders of patella	0.915	0.085	0.000
N42.8 Other specified disorders of prostate	0.000	0.086	0.914
T93 Sequelae of injuries of lower limb	0.909	0.091	0.000
T79 Certain early complications of trauma, not elsewhere classified	0.909	0.091	0.000
N36 Other disorders of urethra	0.000	0.094	0.906
N02.9 Unspecified	0.000	0.097	0.903
E27.4 Other and unspecified adrenocortical insufficiency	0.901	0.099	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.900	0.100	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.898	0.102	0.000
E50-E64 Other nutritional deficiencies	0.898	0.102	0.000
Chapter VII Diseases of the eye and adnexa	0.894	0.106	0.000
L30.9 Dermatitis, unspecified	0.891	0.109	0.000
Chapter XX External causes of morbidity and mortality	0.888	0.112	0.000
N03 Chronic nephritic syndrome	0.000	0.112	0.888
M17.9 Gonarthrosis, unspecified	0.887	0.113	0.000
M11 Other crystal arthropathies	0.886	0.114	0.000
M25.6 Stiffness of joint, not elsewhere classified	0.886	0.114	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.885	0.115	0.000
T93.8 Sequelae of other specified injuries of lower limb	0.884	0.116	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.878	0.122	0.000
D61 Other aplastic anaemias	0.877	0.123	0.000
T92 Sequelae of injuries of upper limb	0.877	0.123	0.000
S20-S29 Injuries to the thorax	0.873	0.127	0.000
M25.71 Osteophyte (Shoulder region)	0.872	0.128	0.000
M25.78 Osteophyte (Other)	0.871	0.129	0.000
Chapter XXII Codes for special purposes	0.868	0.132	0.000
M34.9 Systemic sclerosis, unspecified	0.860	0.140	0.000
N42.1 Congestion and haemorrhage of prostate	0.000	0.140	0.860
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.860	0.140	0.000
S92.3 Fracture of metatarsal bone	0.859	0.141	0.000
N21 Calculus of lower urinary tract	0.000	0.145	0.855
H53-H54 Visual disturbances and blindness	0.852	0.148	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.850	0.149	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.849	0.151	0.000
F05 Delirium, not induced by alcohol and other psychoactive substances	0.849	0.151	0.000
M67 Other disorders of synovium and tendon	0.846	0.154	0.000
M34.1 CR(E)ST syndrome	0.846	0.154	0.000
D69 Purpura and other haemorrhagic conditions	0.845	0.155	0.000
L00-L08 Infections of the skin and subcutaneous tissue	0.845	0.155	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.844	0.156	0.000
M10.0 Idiopathic gout	0.843	0.156	0.000
L50 Urticaria	0.842	0.158	0.000
E10.7 With multiple complications	0.842	0.158	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.840	0.160	0.000
F80-F89 Disorders of psychological development	0.839	0.161	0.000
L28 Lichen simplex chronicus and prurigo	0.838	0.162	0.000
H54 Blindness and low vision	0.838	0.162	0.000
L27.0 Generalised skin eruption due to drugs and medicaments	0.837	0.163	0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified	0.000	0.165	0.835
N02.8 Other	0.000	0.167	0.833
E10.2 With renal complications	0.833	0.167	0.000
E10.8 With unspecified complications	0.831	0.169	0.000
K90-K93 Other diseases of the digestive system	0.830	0.169	0.000
N03.9 Unspecified	0.000	0.170	0.830
M06.4 Inflammatory polyarthropathy	0.828	0.172	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.826	0.174	0.000
D86 Sarcoidosis	0.825	0.175	0.000
D63 Anaemia in chronic diseases classified elsewhere	0.823	0.177	0.000
D55-D59 Haemolytic anaemias	0.822	0.178	0.000
Chapter XI Diseases of the digestive system	0.822	0.178	0.000
S40-S49 Injuries to the shoulder and upper arm	0.822	0.178	0.000
M25.76 Osteophyte (Lower leg)	0.822	0.178	0.000
N41.9 Inflammatory disease of prostate, unspecified	0.000	0.179	0.821
E10.5 With peripheral circulatory complications	0.820	0.180	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.819	0.181	0.000
H30-H36 Disorders of choroid and retina	0.817	0.183	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.816	0.184	0.000
T79.3 Post-traumatic wound infection, not elsewhere classified	0.815	0.185	0.000
S92.30 Fracture of metatarsal bone (closed)	0.815	0.185	0.000
T78 Adverse effects, not elsewhere classified	0.815	0.185	0.000
E53 Deficiency of other B group vitamins	0.813	0.187	0.000
S21 Open wound of thorax	0.812	0.188	0.000
S93.3 Dislocation of other and unspecified parts of foot	0.810	0.190	0.000
L27.1 Localised skin eruption due to drugs and medicaments	0.810	0.190	0.000
M70-M79 Other soft tissue disorders	0.808	0.192	0.000
M22.8 Other disorders of patella	0.805	0.195	0.000
M11.2 Other chondrocalcinosis	0.805	0.195	0.000
E27.2 Addisonian crisis	0.805	0.195	0.000
T92.1 Sequelae of fracture of arm	0.803	0.197	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.799	0.201	0.000
M25.96 Joint disorder, unspecified (Lower leg)	0.798	0.202	0.000
S93.1 Dislocation of toe(s)	0.798	0.202	0.000
M60-M63 Disorders of muscles	0.796	0.204	0.000
L02 Cutaneous abscess, furuncle and carbuncle	0.796	0.204	0.000
M24.1 Other articular cartilage disorders	0.795	0.205	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.795	0.205	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.793	0.207	0.000
N21.0 Calculus in bladder	0.000	0.208	0.792
E88 Other metabolic disorders	0.792	0.208	0.000
L10-L14 Bullous disorders	0.790	0.210	0.000
N36.0 Urethral fistula	0.000	0.210	0.790
D61.9 Aplastic anaemia, unspecified	0.789	0.211	0.000
E40-E46 Malnutrition	0.789	0.211	0.000
H54.7 Unspecified visual loss	0.789	0.211	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.788	0.212	0.000
F40-F48 Neurotic, stress-related and somatoform disorders	0.787	0.213	0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.787	0.213	0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb	0.787	0.213	0.000
S50-S59 Injuries to the elbow and forearm	0.786	0.214	0.000
M10.07 Idiopathic gout (Ankle and foot)	0.786	0.214	0.000
M25.4 Effusion of joint	0.786	0.214	0.000
L52 Erythema nodosum	0.785	0.215	0.000
T90 Sequelae of injuries of head	0.784	0.216	0.000
M00-M03 Infectious arthropathies	0.784	0.216	0.000
S90 Superficial injury of ankle and foot	0.783	0.217	0.000
T71 Asphyxiation	0.783	0.217	0.000
E16.1 Other hypoglycaemia	0.781	0.219	0.000
M25.0 Haemarthrosis	0.781	0.219	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.780	0.220	0.000
N34 Urethritis and urethral syndrome	0.000	0.220	0.780
T20-T25 Burns and corrosions of external body surface, specified by site	0.779	0.221	0.000
M72 Fibroblastic disorders	0.779	0.221	0.000
H36 Retinal disorders in diseases classified elsewhere	0.778	0.222	0.000
N36.2 Urethral caruncle	0.000	0.222	0.778
E73 Lactose intolerance	0.777	0.223	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.775	0.225	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.775	0.225	0.000
T68 Hypothermia	0.775	0.225	0.000
N41.1 Chronic prostatitis	0.000	0.225	0.775
N32.1 Vesicointestinal fistula	0.000	0.226	0.774
W20-W49 Exposure to inanimate mechanical forces	0.772	0.227	0.000
F05.9 Delirium, unspecified	0.772	0.228	0.000
N41.0 Acute prostatitis	0.000	0.228	0.772
M34.8 Other forms of systemic sclerosis	0.772	0.228	0.000
L50.0 Allergic urticaria	0.772	0.228	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.770	0.230	0.000
M25.74 Osteophyte (Hand)	0.770	0.230	0.000
Chapter VI Diseases of the nervous system	0.770	0.230	0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.769	0.231	0.000
K70-K77 Diseases of liver	0.768	0.232	0.000
H43-H45 Disorders of vitreous body and globe	0.767	0.233	0.000
E20 Hypoparathyroidism	0.765	0.235	0.000
E24 Cushing's syndrome	0.764	0.236	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.763	0.236	0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]	0.763	0.237	0.000
S46 Injury of muscle and tendon at shoulder and upper arm level	0.763	0.237	0.000
T79.5 Traumatic anuria	0.762	0.237	0.000
L21 Seborrhoeic dermatitis	0.762	0.238	0.000
T00-T07 Injuries involving multiple body regions	0.761	0.239	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.760	0.240	0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.760	0.240	0.000
L23 Allergic contact dermatitis	0.759	0.240	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.759	0.240	0.000
M14 Arthropathies in other diseases classified elsewhere	0.759	0.241	0.000
M65 Synovitis and tenosynovitis	0.759	0.241	0.000
F45 Somatoform disorders	0.758	0.242	0.000
E10.4 With neurological complications	0.757	0.243	0.000
K90.9 Intestinal malabsorption, unspecified	0.756	0.244	0.000
E84 Cystic fibrosis	0.755	0.245	0.000
M25.95 Joint disorder, unspecified (Pelvic region and thigh)	0.755	0.245	0.000
M23.3 Other meniscus derangements	0.754	0.246	0.000
T92.9 Sequelae of unspecified injury of upper limb	0.753	0.247	0.000
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand	0.752	0.248	0.000
E83.4 Disorders of magnesium metabolism	0.750	0.248	0.002
E07 Other disorders of thyroid	0.751	0.249	0.000
M25.63 Stiffness of joint, not elsewhere classified (Forearm)	0.751	0.249	0.000
M07 Psoriatic and enteropathic arthropathies	0.751	0.249	0.000
H36.0 Diabetic retinopathy	0.750	0.250	0.000
M23.0 Cystic meniscus	0.749	0.251	0.000
M23.6 Other spontaneous disruption of ligament(s) of knee	0.748	0.252	0.000
M10.9 Gout, unspecified	0.747	0.253	0.000
M11.26 Other chondrocalcinosis (Lower leg)	0.747	0.253	0.000
F01 Vascular dementia	0.747	0.253	0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified	0.000	0.255	0.745
E21.0 Primary hyperparathyroidism	0.745	0.255	0.000
E10.1 With ketoacidosis	0.745	0.255	0.000
E34 Other endocrine disorders	0.745	0.255	0.000
M32 Systemic lupus erythematosus	0.744	0.256	0.000
E23 Hypofunction and other disorders of pituitary gland	0.743	0.257	0.000
S31 Open wound of abdomen, lower back and pelvis	0.742	0.258	0.000
N48 Other disorders of penis	0.000	0.259	0.741
S92.4 Fracture of great toe	0.740	0.260	0.000
G50-G59 Nerve, nerve root and plexus disorders	0.740	0.260	0.000
D63.8 Anaemia in other chronic diseases classified elsewhere	0.740	0.260	0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.739	0.261	0.000
M67.8 Other specified disorders of synovium and tendon	0.739	0.261	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.739	0.261	0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.738	0.262	0.000
E21.3 Hyperparathyroidism, unspecified	0.737	0.263	0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.737	0.263	0.000
M67.4 Ganglion	0.737	0.263	0.000
M23.4 Loose body in knee	0.736	0.264	0.000
M25.75 Osteophyte (Pelvic region and thigh)	0.735	0.265	0.000
H46 Optic neuritis	0.735	0.265	0.000
T94 Sequelae of injuries involving multiple and unspecified body regions	0.735	0.265	0.000
M22.3 Other derangements of patella	0.735	0.265	0.000
E29 Testicular dysfunction	0.734	0.265	0.000
T79.8 Other early complications of trauma	0.734	0.266	0.000
D64.8 Other specified anaemias	0.733	0.267	0.000
L28.1 Prurigo nodularis	0.733	0.267	0.000
M25.8 Other specified joint disorders	0.732	0.267	0.000
Y60-Y69 Misadventures to patients during surgical and medical care	0.730	0.269	0.000
E10.6 With other specified complications	0.730	0.270	0.000
S92.2 Fracture of other tarsal bone(s)	0.730	0.270	0.000
L40-L45 Papulosquamous disorders	0.730	0.270	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.728	0.272	0.000
M25.97 Joint disorder, unspecified (Ankle and foot)	0.728	0.272	0.000
U80 Agent resistant to penicillin and related antibiotics	0.726	0.274	0.000
N42.0 Calculus of prostate	0.000	0.274	0.726
M86-M90 Other osteopathies	0.725	0.275	0.000
L20 Atopic dermatitis	0.725	0.275	0.000
M22.2 Patellofemoral disorders	0.725	0.275	0.000
N43 Hydrocele and spermatocele	0.000	0.276	0.724
M33 Dermatopolymyositis	0.722	0.278	0.000
M25.72 Osteophyte (Upper arm)	0.721	0.278	0.000
S29 Other and unspecified injuries of thorax	0.721	0.279	0.000
S92.1 Fracture of talus	0.721	0.279	0.000
M23.8 Other internal derangements of knee	0.720	0.280	0.000
V20-V29 Motorcycle rider injured in transport accident	0.720	0.280	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.720	0.280	0.000
D86.9 Sarcoidosis, unspecified	0.720	0.280	0.000
S52 Fracture of forearm	0.720	0.280	0.000
D50-D53 Nutritional anaemias	0.718	0.282	0.000
E74 Other disorders of carbohydrate metabolism	0.718	0.282	0.000
O34 Maternal care for known or suspected abnormality of pelvic organs	0.718	0.282	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.717	0.283	0.000
E10.0 With coma	0.717	0.283	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.717	0.283	0.000
E00 Congenital iodine-deficiency syndrome	0.717	0.283	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.717	0.283	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.717	0.283	0.000
M30 Polyarteritis nodosa and related conditions	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
N51 Disorders of male genital organs in diseases classified elsewhere	0.000	0.283	0.717
N44 Torsion of testis	0.000	0.283	0.717
E05.8 Other thyrotoxicosis	0.717	0.283	0.000
E05.5 Thyroid crisis or storm	0.717	0.283	0.000
E05.4 Thyrotoxicosis factitia	0.717	0.283	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.717	0.283	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.717	0.283	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.717	0.283	0.000
D64.4 Congenital dyserythropoietic anaemia	0.717	0.283	0.000
D64.3 Other sideroblastic anaemias	0.717	0.283	0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.717	0.283	0.000
D64.1 Secondary sideroblastic anaemia due to disease	0.717	0.283	0.000
D64.0 Hereditary sideroblastic anaemia	0.717	0.283	0.000
M12 Other specific arthropathies	0.717	0.283	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.717	0.283	0.000
M08 Juvenile arthritis	0.717	0.283	0.000
E12 Malnutrition-related diabetes mellitus	0.717	0.283	0.000
N37 Urethral disorders in diseases classified elsewhere	0.000	0.283	0.717
N33 Bladder disorders in diseases classified elsewhere	0.000	0.283	0.717
N32.4 Rupture of bladder, nontraumatic	0.000	0.283	0.717
N32.2 Vesical fistula, not elsewhere classified	0.000	0.283	0.717
N22 Calculus of urinary tract in diseases classified elsewhere	0.000	0.283	0.717
N49.2 Inflammatory disorders of scrotum	0.000	0.283	0.717
M06.8 Other specified rheumatoid arthritis	0.716	0.284	0.000
M06.2 Rheumatoid bursitis	0.716	0.284	0.000
M06.1 Adult-onset Still's disease	0.716	0.284	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.716	0.284	0.000
E32 Diseases of thymus	0.716	0.284	0.000
E31 Polyglandular dysfunction	0.716	0.284	0.000
E30 Disorders of puberty, not elsewhere classified	0.716	0.284	0.000
E25 Adrenogenital disorders	0.716	0.284	0.000
T79.6 Traumatic ischaemia of muscle	0.716	0.284	0.000
T33-T35 Frostbite	0.716	0.284	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.716	0.284	0.000
M25.2 Flail joint	0.715	0.284	0.000
M25.1 Fistula of joint	0.715	0.284	0.000
D83 Common variable immunodeficiency	0.715	0.284	0.000
E27.5 Adrenomedullary hyperfunction	0.715	0.285	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.715	0.285	0.000
E27.0 Other adrenocortical overactivity	0.715	0.285	0.000
E53.8 Deficiency of other specified B group vitamins	0.715	0.285	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.715	0.285	0.000
D80 Immunodeficiency with predominantly antibody defects	0.715	0.285	0.000
E55 Vitamin D deficiency	0.715	0.285	0.000
E03.5 Myxoedema coma	0.713	0.287	0.000
E03.4 Atrophy of thyroid (acquired)	0.713	0.287	0.000
E03.3 Postinfectious hypothyroidism	0.713	0.287	0.000
E03.1 Congenital hypothyroidism without goitre	0.713	0.287	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.713	0.287	0.000
M15 Polyarthrosis	0.713	0.287	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.712	0.288	0.000
M25.79 Osteophyte (Site unspecified)	0.711	0.288	0.000
M25.73 Osteophyte (Forearm)	0.711	0.288	0.000
M25.70 Osteophyte (Multiple sites)	0.711	0.288	0.000
F80 Specific developmental disorders of speech and language	0.710	0.290	0.000
T16 Foreign body in ear	0.710	0.290	0.000
M91-M94 Chondropathies	0.709	0.291	0.000
L53 Other erythematous conditions	0.709	0.291	0.000
L02.1 Cutaneous abscess, furuncle and carbuncle of neck	0.709	0.291	0.000
H43 Disorders of vitreous body	0.709	0.291	0.000
N46 Male infertility	0.000	0.291	0.709
K35-K38 Diseases of appendix	0.708	0.292	0.000
H54.4 Blindness, one eye	0.708	0.292	0.000
M24.6 Ankylosis of joint	0.707	0.293	0.000
F45.8 Other somatoform disorders	0.707	0.293	0.000
N23 Unspecified renal colic	0.000	0.294	0.706
K75 Other inflammatory liver diseases	0.706	0.294	0.000
X20-X29 Contact with venomous animals and plants	0.706	0.294	0.000
L25 Unspecified contact dermatitis	0.706	0.294	0.000
L24 Irritant contact dermatitis	0.706	0.294	0.000
L26 Exfoliative dermatitis	0.706	0.294	0.000
L22 Diaper [napkin] dermatitis	0.706	0.294	0.000
S92.7 Multiple fractures of foot	0.706	0.294	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.705	0.294	0.000
F05.8 Other delirium	0.705	0.295	0.000
W50-W64 Exposure to animate mechanical forces	0.705	0.295	0.000
S21.9 Open wound of thorax, part unspecified	0.705	0.295	0.000
X60-X84 Intentional self-harm	0.705	0.295	0.000
M31 Other necrotising vasculopathies	0.704	0.296	0.000
M24.5 Contracture of joint	0.704	0.296	0.000
T78.1 Other adverse food reactions, not elsewhere classified	0.703	0.296	0.000
D69.6 Thrombocytopenia, unspecified	0.703	0.297	0.000
M23.30 Other meniscus derangements (Multiple sites)	0.703	0.297	0.000
F60-F69 Disorders of adult personality and behaviour	0.703	0.297	0.000
M06.3 Rheumatoid nodule	0.702	0.298	0.000
E15 Nondiabetic hypoglycaemic coma	0.702	0.298	0.000
U80.1 Methicillin resistant agent	0.702	0.298	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.701	0.299	0.000
H47 Other disorders of optic [2nd] nerve and visual pathways	0.701	0.299	0.000
S98 Traumatic amputation of ankle and foot	0.700	0.300	0.000
S97 Crushing injury of ankle and foot	0.700	0.300	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.700	0.300	0.000
S95 Injury of blood vessels at ankle and foot level	0.700	0.300	0.000
S94 Injury of nerves at ankle and foot level	0.700	0.300	0.000
M23.9 Internal derangement of knee, unspecified	0.700	0.300	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.699	0.301	0.000
M35.8 Other specified systemic involvement of connective tissue	0.699	0.301	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.699	0.301	0.000
M35.5 Multifocal fibrosclerosis	0.699	0.301	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.699	0.301	0.000
M35.2 Behcet's disease	0.699	0.301	0.000
M17.3 Other posttraumatic gonarthrosis	0.699	0.301	0.000
T98 Sequelae of other and unspecified effects of external causes	0.699	0.301	0.000
T95 Sequelae of burns, corrosions and frostbite	0.698	0.302	0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.698	0.302	0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.698	0.302	0.000
F81 Specific developmental disorders of scholastic skills	0.697	0.302	0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.696	0.304	0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.696	0.304	0.000
O34.2 Maternal care due to uterine scar from previous surgery	0.695	0.305	0.000
E79 Disorders of purine and pyrimidine metabolism	0.695	0.305	0.000
E77 Disorders of glycoprotein metabolism	0.695	0.305	0.000
E76 Disorders of glycosaminoglycan metabolism	0.695	0.305	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.695	0.305	0.000
E72 Other disorders of amino-acid metabolism	0.695	0.305	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.695	0.305	0.000
E70 Disorders of aromatic amino-acid metabolism	0.695	0.305	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.695	0.305	0.000
S36 Injury of intra-abdominal organs	0.694	0.306	0.000
N07 Hereditary nephropathy, not elsewhere classified	0.000	0.306	0.694
N06 Isolated proteinuria with specified morphological lesion	0.000	0.306	0.694
N01 Rapidly progressive nephritic syndrome	0.000	0.306	0.694
N00 Acute nephritic syndrome	0.000	0.306	0.694
E83.9 Disorder of mineral metabolism, unspecified	0.689	0.308	0.004
E83.8 Other disorders of mineral metabolism	0.689	0.308	0.004
E83.2 Disorders of zinc metabolism	0.689	0.308	0.004
E83.0 Disorders of copper metabolism	0.689	0.308	0.004
S93.0 Dislocation of ankle joint	0.692	0.308	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.691	0.309	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.691	0.309	0.000
E16.4 Abnormal secretion of gastrin	0.691	0.309	0.000
E16.3 Increased secretion of glucagon	0.691	0.309	0.000
F99-F99 Unspecified mental disorder	0.690	0.310	0.000
M76 Enthesopathies of lower limb, excluding foot	0.689	0.311	0.000
N42.3 Dysplasia of prostate	0.000	0.311	0.689
Q20-Q28 Congenital malformations of the circulatory system	0.689	0.311	0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.689	0.311	0.000
H54.6 Unqualified visual loss, one eye	0.689	0.311	0.000
M34.2 Systemic sclerosis induced by drugs and chemicals	0.688	0.312	0.000
M34.0 Progressive systemic sclerosis	0.688	0.312	0.000
E03.8 Other specified hypothyroidism	0.686	0.314	0.000
N08 Glomerular disorders in diseases classified elsewhere	0.000	0.315	0.685
G58 Other mononeuropathies	0.685	0.315	0.000
T93.9 Sequelae of unspecified injury of lower limb	0.684	0.316	0.000
H43.1 Vitreous haemorrhage	0.684	0.316	0.000
M24.2 Disorder of ligament	0.683	0.316	0.000
D84 Other immunodeficiencies	0.683	0.317	0.000
M17.4 Other secondary gonarthrosis, bilateral	0.683	0.317	0.000
M17.2 Posttraumatic gonarthrosis, bilateral	0.683	0.317	0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.682	0.318	0.000
F70-F79 Mental retardation	0.682	0.318	0.000
M80-M85 Disorders of bone density and structure	0.682	0.318	0.000
G70-G73 Diseases of myoneural junction and muscle	0.682	0.318	0.000
N36.3 Prolapsed urethral mucosa	0.000	0.318	0.682
M23.5 Chronic instability of knee	0.681	0.319	0.000
G62 Other polyneuropathies	0.681	0.319	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.680	0.320	0.000
S21.1 Open wound of front wall of thorax	0.679	0.321	0.000
M17.5 Other secondary gonarthrosis	0.678	0.322	0.000
S52.0 Fracture of upper end of ulna	0.677	0.323	0.000
O46 Antepartum haemorrhage, not elsewhere classified	0.677	0.323	0.000
H34 Retinal vascular occlusions	0.677	0.323	0.000
F02 Dementia in other diseases classified elsewhere	0.677	0.323	0.000
Y00-Y09 Assault	0.676	0.324	0.000
O36 Maternal care for other known or suspected foetal problems	0.676	0.324	0.000
M24.9 Joint derangement, unspecified	0.675	0.324	0.000
M24.7 Protrusio acetabuli	0.675	0.324	0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.675	0.325	0.000
G51 Facial nerve disorders	0.674	0.326	0.000
Q80-Q89 Other congenital malformations	0.673	0.327	0.000
N02.7 Diffuse crescentic glomerulonephritis	0.000	0.327	0.673
N02.6 Dense deposit disease	0.000	0.327	0.673
N02.5 Diffuse mesangiocapillary glomerulonephritis	0.000	0.327	0.673
N02.4 Diffuse endocapillary proliferative glomerulonephritis	0.000	0.327	0.673
N02.3 Diffuse mesangial proliferative glomerulonephritis	0.000	0.327	0.673
N02.1 Focal and segmental glomerular lesions	0.000	0.327	0.673
N02.0 Minor glomerular abnormality	0.000	0.327	0.673
L30.8 Other specified dermatitis	0.673	0.327	0.000
D59 Acquired haemolytic anaemia	0.673	0.327	0.000
N41.8 Other inflammatory diseases of prostate	0.000	0.328	0.672
N41.3 Prostatocystitis	0.000	0.328	0.672
N41.2 Abscess of prostate	0.000	0.328	0.672
T75 Effects of other external causes	0.672	0.328	0.000
T74 Maltreatment syndromes	0.672	0.328	0.000
T73 Effects of other deprivation	0.672	0.328	0.000
T70 Effects of air pressure and water pressure	0.672	0.328	0.000
T69 Other effects of reduced temperature	0.672	0.328	0.000
T67 Effects of heat and light	0.672	0.328	0.000
T66 Unspecified effects of radiation	0.672	0.328	0.000
K35 Acute appendicitis	0.672	0.328	0.000
E28 Ovarian dysfunction	0.671	0.329	0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)	0.670	0.330	0.000
K70 Alcoholic liver disease	0.670	0.330	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.670	0.330	0.000
E27.9 Disorder of adrenal gland, unspecified	0.670	0.330	0.000
T78.8 Other adverse effects, not elsewhere classified	0.669	0.331	0.000
Q50-Q56 Congenital malformations of genital organs	0.669	0.331	0.000
E53.9 Vitamin B deficiency, unspecified	0.669	0.331	0.000
L54 Erythema in diseases classified elsewhere	0.669	0.331	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations