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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs9257827
log Bayes Factor = 49.0885
Chromosome 6   position 29,362,903  (GRCh37) Explore rs9257827 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.001 0.999
E05.9 Thyrotoxicosis, unspecified
0.000 0.001 0.999
E20-E35 Disorders of other endocrine glands
0.000 0.001 0.999
E10.3 With ophthalmic complications
0.000 0.002 0.998
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.004 0.996
E27 Other disorders of adrenal gland
0.000 0.008 0.992
E10.2 With renal complications
0.000 0.012 0.988
E27.1 Primary adrenocortical insufficiency
0.000 0.017 0.983
E13 Other specified diabetes mellitus
0.000 0.047 0.953
E14 Unspecified diabetes mellitus
0.000 0.050 0.950
E24 Cushing's syndrome
0.000 0.053 0.947
E10.4 With neurological complications
0.000 0.069 0.931
E13.9 Without complications
0.000 0.078 0.922
E10.1 With ketoacidosis
0.000 0.082 0.918
E14.3 With ophthalmic complications
0.000 0.107 0.893
E50-E64 Other nutritional deficiencies
0.000 0.107 0.893
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.110 0.890
E20 Hypoparathyroidism
0.000 0.113 0.887
E23 Hypofunction and other disorders of pituitary gland
0.000 0.115 0.885
E24.0 Pituitary-dependent Cushing's disease
0.000 0.147 0.853
L40.9 Psoriasis, unspecified
0.851 0.149 0.000
E24.9 Cushing's syndrome, unspecified
0.000 0.180 0.820
E05.8 Other thyrotoxicosis
0.000 0.184 0.816
E23.0 Hypopituitarism
0.000 0.192 0.808
E20.9 Hypoparathyroidism, unspecified
0.000 0.193 0.807
E29 Testicular dysfunction
0.000 0.198 0.802
E14.6 With other specified complications
0.000 0.206 0.794
E55 Vitamin D deficiency
0.000 0.207 0.793
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.210 0.790
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.212 0.788
E22 Hyperfunction of pituitary gland
0.000 0.215 0.785
E10.0 With coma
0.000 0.219 0.780
E03 Other hypothyroidism
0.000 0.230 0.770
E53 Deficiency of other B group vitamins
0.000 0.232 0.768
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.245 0.755
E10.7 With multiple complications
0.000 0.255 0.745
E14.2 Withrenal complications
0.000 0.261 0.739
E53.9 Vitamin B deficiency, unspecified
0.000 0.263 0.737
E51 Thiamine deficiency
0.000 0.264 0.736
E24.2 Drug-induced Cushing's syndrome
0.000 0.273 0.727
E55.9 Vitamin D deficiency, unspecified
0.000 0.278 0.722
E40-E46 Malnutrition
0.000 0.279 0.721
E23.2 Diabetes insipidus
0.000 0.279 0.721
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.284 0.716
E32 Diseases of thymus
0.000 0.284 0.716
E30 Disorders of puberty, not elsewhere classified
0.000 0.284 0.716
E27.5 Adrenomedullary hyperfunction
0.000 0.288 0.712
E27.0 Other adrenocortical overactivity
0.000 0.288 0.712
E14.5 With peripheral circulatory complications
0.000 0.297 0.703
E25 Adrenogenital disorders
0.000 0.300 0.700
L40 Psoriasis
0.694 0.306 0.000
E27.8 Other specified disorders of adrenal gland
0.000 0.312 0.688
E10.6 With other specified complications
0.000 0.316 0.684
E10.8 With unspecified complications
0.000 0.316 0.684
E13.8 With unspecified complications
0.000 0.317 0.683
E13.7 With multiple complications
0.000 0.317 0.683
E13.6 With other specified complications
0.000 0.317 0.683
E13.5 With peripheral circulatory complications
0.000 0.317 0.683
E13.4 With neurological complications
0.000 0.317 0.683
E13.2 With renal complications
0.000 0.317 0.683
E13.1 With ketoacidosis
0.000 0.317 0.683
E13.0 With coma
0.000 0.317 0.683
E14.8 With unspecified complications
0.000 0.317 0.683
E14.7 With multiple complications
0.000 0.319 0.681
E14.0 With coma
0.000 0.319 0.681
E31 Polyglandular dysfunction
0.000 0.320 0.680
E24.8 Other Cushing's syndrome
0.000 0.321 0.679
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.321 0.679
E24.3 Ectopic ACTH syndrome
0.000 0.321 0.679
E24.1 Nelson's syndrome
0.000 0.321 0.679
E22.0 Acromegaly and pituitary gigantism
0.000 0.325 0.675
E14.1 With ketoacidosis
0.000 0.338 0.662
E29.1 Testicular hypofunction
0.000 0.339 0.661
E27.9 Disorder of adrenal gland, unspecified
0.000 0.343 0.657
E13.3 With ophthalmic complications
0.000 0.343 0.656
E10.5 With peripheral circulatory complications
0.000 0.354 0.645
E28 Ovarian dysfunction
0.000 0.355 0.645
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.356 0.643
E06 Thyroiditis
0.000 0.358 0.642
E14.9 Without complications
0.000 0.359 0.641
E61 Deficiency of other nutrient elements
0.000 0.359 0.641
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.360 0.640
E50 Vitamin A deficiency
0.000 0.360 0.640
E60 Dietary zinc deficiency
0.000 0.360 0.640
E59 Dietary selenium deficiency
0.000 0.360 0.640
E52 Niacin deficiency [pellagra]
0.000 0.360 0.640
E20.8 Other hypoparathyroidism
0.000 0.364 0.636
E20.1 Pseudohypoparathyroidism
0.000 0.364 0.636
E20.0 Idiopathic hypoparathyroidism
0.000 0.364 0.636
E16 Other disorders of pancreatic internal secretion
0.000 0.365 0.635
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.365 0.635
E23.1 Drug-induced hypopituitarism
0.000 0.365 0.635
E14.4 With neurological complications
0.000 0.369 0.631
E51.2 Wernicke's encephalopathy
0.000 0.376 0.624
L40.5 Arthropathic psoriasis
0.613 0.387 0.000
E23.7 Disorder of pituitary gland, unspecified
0.000 0.392 0.608
E03.9 Hypothyroidism, unspecified
0.000 0.393 0.607
K90 Intestinal malabsorption
0.000 0.397 0.603
E58 Dietary calcium deficiency
0.000 0.401 0.599
E56 Other vitamin deficiencies
0.000 0.402 0.598
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.406 0.594
E26 Hyperaldosteronism
0.000 0.406 0.593
E27.2 Addisonian crisis
0.000 0.416 0.584
L40.8 Other psoriasis
0.579 0.421 0.000
E07 Other disorders of thyroid
0.000 0.424 0.576
E22.1 Hyperprolactinaemia
0.000 0.425 0.575
E29.9 Testicular dysfunction, unspecified
0.000 0.425 0.575
E29.8 Other testicular dysfunction
0.000 0.425 0.575
E29.0 Testicular hyperfunction
0.000 0.425 0.575
L40.0 Psoriasis vulgaris
0.575 0.425 0.000
E55.0 Rickets, active
0.000 0.431 0.569
E03.1 Congenital hypothyroidism without goitre
0.000 0.433 0.567
E15 Nondiabetic hypoglycaemic coma
0.000 0.435 0.565
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.437 0.563
E22.8 Other hyperfunction of pituitary gland
0.000 0.437 0.563
E34 Other endocrine disorders
0.000 0.441 0.559
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.446 0.554
E03.5 Myxoedema coma
0.000 0.447 0.552
E03.4 Atrophy of thyroid (acquired)
0.000 0.447 0.552
E03.3 Postinfectious hypothyroidism
0.000 0.447 0.552
E63 Other nutritional deficiencies
0.000 0.448 0.551
E53.1 Pyridoxine deficiency
0.000 0.450 0.550
E53.0 Riboflavin deficiency
0.000 0.450 0.550
E54 Ascorbic acid deficiency
0.000 0.457 0.543
E16.1 Other hypoglycaemia
0.000 0.464 0.536
E51.9 Thiamine deficiency, unspecified
0.000 0.472 0.528
E51.8 Other manifestations of thiamine deficiency
0.000 0.472 0.528
E51.1 Beriberi
0.000 0.472 0.528
E23.6 Other disorders of pituitary gland
0.000 0.478 0.522
E46 Unspecified protein-energy malnutrition
0.000 0.478 0.522
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.483 0.517
E45 Retarded development following protein-energy malnutrition
0.000 0.483 0.517
E43 Unspecified severe protein-energy malnutrition
0.000 0.483 0.517
E42 Marasmic kwashiorkor
0.000 0.483 0.517
E41 Nutritional marasmus
0.000 0.483 0.517
E40 Kwashiorkor
0.000 0.483 0.517
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E30.9 Disorder of puberty, unspecified
0.000 0.486 0.513
E30.8 Other disorders of puberty
0.000 0.486 0.513
E30.1 Precocious puberty
0.000 0.486 0.513
E30.0 Delayed puberty
0.000 0.486 0.513
E32.9 Disease of thymus, unspecified
0.000 0.486 0.513
E32.8 Other diseases of thymus
0.000 0.486 0.513
E32.1 Abscess of thymus
0.000 0.486 0.513
E32.0 Persistent hyperplasia of thymus
0.000 0.486 0.513
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.486 0.513
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.486 0.513
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.486 0.513
E61.2 Magnesium deficiency
0.000 0.495 0.504
E25.9 Adrenogenital disorder, unspecified
0.000 0.498 0.502
E25.8 Other adrenogenital disorders
0.000 0.498 0.502
L40.2 Acrodermatitis continua
0.497 0.502 0.000
K90.9 Intestinal malabsorption, unspecified
0.000 0.509 0.491
E31.9 Polyglandular dysfunction, unspecified
0.000 0.512 0.488
E31.8 Other polyglandular dysfunction
0.000 0.512 0.488
E31.1 Polyglandular hyperfunction
0.000 0.512 0.488
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.514 0.486
L40.3 Pustulosis palmaris et plantaris
0.484 0.516 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.517 0.483
L40.4 Guttate psoriasis
0.481 0.519 0.000
E03.8 Other specified hypothyroidism
0.000 0.522 0.478
L40.1 Generalised pustular psoriasis
0.472 0.528 0.000
E06.9 Thyroiditis, unspecified
0.000 0.532 0.467
E28.9 Ovarian dysfunction, unspecified
0.000 0.537 0.463
E28.8 Other ovarian dysfunction
0.000 0.537 0.463
E28.1 Androgen excess
0.000 0.537 0.463
E28.0 Oestrogen excess
0.000 0.537 0.463
E06.3 Autoimmune thyroiditis
0.000 0.539 0.461
E06.4 Drug-induced thyroiditis
0.000 0.540 0.460
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.540 0.460
E06.1 Subacute thyroiditis
0.000 0.540 0.460
E06.0 Acute thyroiditis
0.000 0.540 0.460
E61.9 Deficiency of nutrient element, unspecified
0.000 0.540 0.459
E61.8 Deficiency of other specified nutrient elements
0.000 0.540 0.459
E61.7 Deficiency of multiple nutrient elements
0.000 0.540 0.459
E61.6 Vanadium deficiency
0.000 0.540 0.459
E61.5 Molybdenum deficiency
0.000 0.540 0.459
E61.4 Chromium deficiency
0.000 0.540 0.459
E61.3 Manganese deficiency
0.000 0.540 0.459
E61.0 Copper deficiency
0.000 0.540 0.459
E50.9 Vitamin A deficiency, unspecified
0.000 0.541 0.459
E50.8 Other manifestations of vitamin A deficiency
0.000 0.541 0.459
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.541 0.459
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.541 0.459
E50.5 Vitamin A deficiency with night blindness
0.000 0.541 0.459
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.541 0.459
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.541 0.459
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.541 0.459
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.541 0.459
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.541 0.459
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.541 0.459
E64.8 Sequelae of other nutritional deficiencies
0.000 0.541 0.459
E64.3 Sequelae of rickets
0.000 0.541 0.459
E64.2 Sequelae of vitamin C deficiency
0.000 0.541 0.459
E64.1 Sequelae of vitamin A deficiency
0.000 0.541 0.459
E64.0 Sequelae of protein-energy malnutrition
0.000 0.541 0.459
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.544 0.456
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.544 0.456
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.544 0.456
E16.4 Abnormal secretion of gastrin
0.000 0.544 0.456
E16.3 Increased secretion of glucagon
0.000 0.544 0.456
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.544 0.455
E28.2 Polycystic ovarian syndrome
0.000 0.545 0.455
E31.0 Autoimmune polyglandular failure
0.000 0.548 0.452
E26.9 Hyperaldosteronism, unspecified
0.000 0.559 0.441
E16.2 Hypoglycaemia, unspecified
0.000 0.562 0.438
K90.3 Pancreatic steatorrhoea
0.000 0.567 0.432
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.567 0.432
K90.1 Tropical sprue
0.000 0.567 0.432
E56.9 Vitamin deficiency, unspecified
0.000 0.571 0.429
E56.8 Deficiency of other vitamins
0.000 0.571 0.429
E56.0 Deficiency of vitamin E
0.000 0.571 0.429
E26.8 Other hyperaldosteronism
0.000 0.574 0.426
E26.1 Secondary hyperaldosteronism
0.000 0.574 0.426
K90.8 Other intestinal malabsorption
0.000 0.583 0.416
E07.1 Dyshormogenetic goitre
0.000 0.587 0.413
E07.0 Hypersecretion of calcitonin
0.000 0.587 0.413
E34.3 Short stature, not elsewhere classified
0.000 0.593 0.407
E28.3 Primary ovarian failure
0.000 0.597 0.402
E34.5 Androgen resistance syndrome
0.000 0.599 0.401
E34.4 Constitutional tall stature
0.000 0.599 0.401
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.599 0.401
E34.1 Other hypersecretion of intestinal hormones
0.000 0.599 0.401
E61.1 Iron deficiency
0.000 0.599 0.401
E63.8 Other specified nutritional deficiencies
0.000 0.604 0.395
E63.1 Imbalance of constituents of food intake
0.000 0.604 0.395
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.604 0.395
E56.1 Deficiency of vitamin K
0.000 0.613 0.386
E06.5 Other chronic thyroiditis
0.000 0.625 0.375
E44.1 Mild protein-energy malnutrition
0.000 0.629 0.371
E44.0 Moderate protein-energy malnutrition
0.000 0.629 0.371
E34.8 Other specified endocrine disorders
0.000 0.634 0.365
E34.9 Endocrine disorder, unspecified
0.000 0.635 0.365
E07.9 Disorder of thyroid, unspecified
0.000 0.641 0.359
E07.8 Other specified disorders of thyroid
0.000 0.651 0.349
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.001 0.653 0.346
E34.0 Carcinoid syndrome
0.000 0.658 0.342
E63.9 Nutritional deficiency, unspecified
0.001 0.693 0.307
E26.0 Primary hyperaldosteronism
0.001 0.726 0.273
E65-E68 Obesity and other hyperalimentation
0.000 0.735 0.265
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.798 0.202
E67 Other hyperalimentation
0.000 0.810 0.190
E68 Sequelae of hyperalimentation
0.000 0.810 0.190
E53.8 Deficiency of other specified B group vitamins
0.000 0.854 0.146
E21.4 Other specified disorders of parathyroid gland
0.000 0.855 0.145
E21.2 Other hyperparathyroidism
0.000 0.856 0.144
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.863 0.137
E67.8 Other specified hyperalimentation
0.000 0.863 0.136
E67.3 Hypervitaminosis D
0.000 0.863 0.136
E67.2 Megavitamin-B6 syndrome
0.000 0.863 0.136
E67.1 Hypercarotenaemia
0.000 0.863 0.136
E67.0 Hypervitaminosis A
0.000 0.863 0.136
E11 Non-insulin-dependent diabetes mellitus
0.000 0.871 0.129
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.874 0.125
E11.9 Without complications
0.000 0.882 0.118
E04 Other non-toxic goitre
0.001 0.891 0.108
M35.0 Sicca syndrome [Sjogren]
0.000 0.896 0.104
L40-L45 Papulosquamous disorders
0.102 0.897 0.001
E65 Localised adiposity
0.001 0.898 0.101
E11.6 With other specified complications
0.000 0.903 0.097
E11.2 With renal complications
0.000 0.903 0.097
E11.7 With multiple complications
0.000 0.907 0.093
E11.8 With unspecified complications
0.000 0.911 0.089
E04.8 Other specified non-toxic goitre
0.001 0.921 0.078
E21.3 Hyperparathyroidism, unspecified
0.000 0.922 0.078
E04.9 Non-toxic goitre, unspecified
0.000 0.923 0.077
E11.0 With coma
0.000 0.925 0.075
L44 Other papulosquamous disorders
0.073 0.926 0.001
L41 Parapsoriasis
0.073 0.926 0.001
L45 Papulosquamous disorders in diseases classified elsewhere
0.073 0.926 0.001
E83 Disorders of mineral metabolism
0.059 0.940 0.001
E11.1 With ketoacidosis
0.000 0.942 0.058
L42 Pityriasis rosea
0.053 0.946 0.001
L41.9 Parapsoriasis, unspecified
0.053 0.947 0.001
L41.8 Other parapsoriasis
0.053 0.947 0.001
L41.5 Retiform parapsoriasis
0.053 0.947 0.001
L41.4 Large plaque parapsoriasis
0.053 0.947 0.001
L41.3 Small plaque parapsoriasis
0.053 0.947 0.001
L41.2 Lymphomatoid papulosis
0.053 0.947 0.001
L41.1 Pityriasis lichenoides chronica
0.053 0.947 0.001
L41.0 Pityriasis lichenoides et varioliformis acuta
0.053 0.947 0.001
L44.9 Papulosquamous disorder, unspecified
0.053 0.947 0.001
L44.8 Other specified papulosquamous disorders
0.053 0.947 0.001
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.053 0.947 0.001
L44.3 Lichen ruber moniliformis
0.053 0.947 0.001
L44.2 Lichen striatus
0.053 0.947 0.001
L44.1 Lichen nitidus
0.053 0.947 0.001
L44.0 Pityriasis rubra pilaris
0.053 0.947 0.001
E04.0 Non-toxic diffuse goitre
0.001 0.949 0.050
E83.8 Other disorders of mineral metabolism
0.042 0.957 0.001
E83.2 Disorders of zinc metabolism
0.042 0.957 0.001
E83.0 Disorders of copper metabolism
0.042 0.957 0.001
E83.9 Disorder of mineral metabolism, unspecified
0.042 0.957 0.001
K90-K93 Other diseases of the digestive system
0.000 0.961 0.039
E11.5 With peripheral circulatory complications
0.000 0.961 0.039
E21.0 Primary hyperparathyroidism
0.000 0.964 0.036
E83.3 Disorders of phosphorus metabolism
0.035 0.965 0.000
L43 Lichen planus
0.031 0.968 0.001
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.972 0.028
L43.3 Subacute (active) lichen planus
0.022 0.977 0.001
L43.2 Lichenoid drug reaction
0.022 0.977 0.001
L43.1 Bullous lichen planus
0.022 0.977 0.001
L43.0 Hypertrophic lichen planus
0.022 0.977 0.001
E66 Obesity
0.000 0.977 0.023
E11.4 With neurological complications
0.000 0.978 0.022
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.979 0.020
K93.1 Megacolon in Chagas' disease
0.000 0.979 0.020
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.979 0.020
E11.3 With ophthalmic complications
0.000 0.982 0.018
T84.1 Mechanical complication of internal fixation device of bones of limb
0.000 0.983 0.017
E66.1 Drug-induced obesity
0.000 0.983 0.016
L43.8 Other lichen planus
0.015 0.983 0.001
E83.4 Disorders of magnesium metabolism
0.015 0.985 0.001
M35 Other systemic involvement of connective tissue
0.000 0.985 0.015
E66.0 Obesity due to excess calories
0.000 0.985 0.015
B97.8 Other viral agents as the cause of diseases classified to other chapters
0.012 0.988 0.000
H90 Conductive and sensorineural hearing loss
0.000 0.988 0.012
H26.9 Cataract, unspecified
0.000 0.988 0.012
H90.3 Sensorineural hearing loss, bilateral
0.000 0.988 0.012
H90.8 Mixed conductive and sensorineural hearing loss, unspecified
0.000 0.989 0.011
H90.5 Sensorineural hearing loss, unspecified
0.000 0.989 0.011
H90.2 Conductive hearing loss, unspecified
0.000 0.989 0.011
M35.8 Other specified systemic involvement of connective tissue
0.000 0.989 0.011
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.989 0.011
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.989 0.011
M35.5 Multifocal fibrosclerosis
0.000 0.989 0.011
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.989 0.011
M35.2 Behcet's disease
0.000 0.990 0.010
M35.1 Other overlap syndromes
0.000 0.990 0.010
C50.3 Lower-inner quadrant of breast
0.000 0.990 0.010
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.990 0.010
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
0.000 0.990 0.010
H90.6 Mixed conductive and sensorineural hearing loss, bilateral
0.000 0.990 0.010
E04.2 Non-toxic multinodular goitre
0.001 0.991 0.009
M35.7 Hypermobility syndrome
0.000 0.991 0.009
E04.1 Non-toxic single thyroid nodule
0.002 0.991 0.007
E83.5 Disorders of calcium metabolism
0.008 0.991 0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
0.000 0.992 0.008
X41.9 Unspecified place
0.008 0.992 0.000
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified
0.000 0.992 0.008
M22.2 Patellofemoral disorders
0.000 0.993 0.007
H90.0 Conductive hearing loss, bilateral
0.000 0.993 0.006
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
0.000 0.993 0.007
H26.4 After-cataract
0.000 0.994 0.006
A08.4 Viral intestinal infection, unspecified
0.000 0.994 0.006
L27.0 Generalised skin eruption due to drugs and medicaments
0.000 0.994 0.006
H26 Other cataract
0.000 0.994 0.006
H26.1 Traumatic cataract
0.000 0.994 0.006
B97 Viral agents as the cause of diseases classified to other chapters
0.005 0.995 0.000
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified
0.005 0.995 0.000
K92 Other diseases of digestive system
0.002 0.995 0.003
N08.3 Glomerular disorders in diabetes mellitus
0.000 0.995 0.005
H26.2 Complicated cataract
0.000 0.995 0.005
A87.9 Viral meningitis, unspecified
0.000 0.995 0.005
B97.7 Papillomavirus as the cause of diseases classified to other chapters
0.005 0.995 0.000
H26.3 Drug-induced cataract
0.000 0.995 0.004
S82.10 Fracture of upper end of tibia (closed)
0.000 0.996 0.004
B97.6 Parvovirus as the cause of diseases classified to other chapters
0.004 0.996 0.000
B97.5 Reovirus as the cause of diseases classified to other chapters
0.004 0.996 0.000
B97.3 Retrovirus as the cause of diseases classified to other chapters
0.004 0.996 0.000
B97.2 Coronavirus as the cause of diseases classified to other chapters
0.004 0.996 0.000
B97.0 Adenovirus as the cause of diseases classified to other chapters
0.004 0.996 0.000
X41.0 Home
0.004 0.996 0.000
X41.8 Other specified place
0.004 0.996 0.000
X41.7 Farm
0.004 0.996 0.000
X41.6 Industrial and construction area
0.004 0.996 0.000
X41.5 Trade and service area
0.004 0.996 0.000
X41.4 Street and highway
0.004 0.996 0.000
X41.3 Sports and athletics area
0.004 0.996 0.000
X41.2 School, other institution and public administrative area
0.004 0.996 0.000
X41.1 Residential institution
0.004 0.996 0.000
E70-E90 Metabolic disorders
0.001 0.996 0.004
M25.76 Osteophyte (Lower leg)
0.000 0.996 0.004
B97.4 Respiratory synctial virus as the cause of diseases classified to other chapters
0.004 0.996 0.000
L43.9 Lichen planus, unspecified
0.002 0.996 0.002
M34.1 CR(E)ST syndrome
0.000 0.996 0.004
M22 Disorders of patella
0.000 0.996 0.004
B97.1 Enterovirus as the cause of diseases classified to other chapters
0.004 0.996 0.000
K92.9 Disease of digestive system, unspecified
0.000 0.996 0.004
M34 Systemic sclerosis
0.000 0.996 0.004
K92.8 Other specified diseases of digestive system
0.003 0.996 0.001
M34.9 Systemic sclerosis, unspecified
0.000 0.996 0.004
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.996 0.003
M31.6 Other giant cell arteritis
0.000 0.996 0.004
E73 Lactose intolerance
0.000 0.996 0.003
M35.3 Polymyalgia rheumatica
0.000 0.997 0.003
N08 Glomerular disorders in diseases classified elsewhere
0.000 0.997 0.003
M22.8 Other disorders of patella
0.000 0.997 0.003
E79 Disorders of purine and pyrimidine metabolism
0.000 0.997 0.003
D47.4 Osteomyelofibrosis
0.000 0.997 0.003
K92.0 Haematemesis
0.003 0.997 0.000
M34.8 Other forms of systemic sclerosis
0.000 0.997 0.003
M22.0 Recurrent dislocation of patella
0.000 0.997 0.003
E70 Disorders of aromatic amino-acid metabolism
0.001 0.997 0.003
X41.08 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, antiparkinsonism and psychotropic drugs, not elsewhere classified , Home ,While engaged in other specified activities
0.003 0.997 0.000
E66.8 Other obesity
0.000 0.997 0.003
E77 Disorders of glycoprotein metabolism
0.001 0.997 0.003
E76 Disorders of glycosaminoglycan metabolism
0.001 0.997 0.003
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.001 0.997 0.003
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.001 0.997 0.003
L53.9 Erythematous condition, unspecified
0.003 0.997 0.000
C77.4 Inguinal and lower limb lymph nodes
0.000 0.997 0.003
E74 Other disorders of carbohydrate metabolism
0.000 0.997 0.003
X40-X49 Accidental poisoning by and exposure to noxious substances
0.003 0.997 0.000
K91.2 Postsurgical malabsorption, not elsewhere classified
0.000 0.997 0.003
N48.4 Impotence of organic origin
0.003 0.997 0.000
M88.90 Paget's disease of bone, unspecified (Multiple sites)
0.000 0.997 0.003
E84 Cystic fibrosis
0.001 0.997 0.003
E73.9 Lactose intolerance, unspecified
0.000 0.997 0.003
A08 Viral and other specified intestinal infections
0.000 0.997 0.003
L27 Dermatitis due to substances taken internally
0.000 0.997 0.003
M22.1 Recurrent subluxation of patella
0.000 0.997 0.003
M22.9 Disorder of patella, unspecified
0.000 0.997 0.003
E72 Other disorders of amino-acid metabolism
0.001 0.997 0.002
E85 Amyloidosis
0.000 0.997 0.003
K51.4 Pseudopolyposis of colon
0.003 0.997 0.000
K92.1 Melaena
0.003 0.997 0.000
M34.2 Systemic sclerosis induced by drugs and chemicals
0.000 0.997 0.003
X49 Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances
0.003 0.997 0.000
A08.3 Other viral enteritis
0.000 0.997 0.003
H26.0 Infantile, juvenile and presenile cataract
0.002 0.997 0.001
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.997 0.003
M34.0 Progressive systemic sclerosis
0.000 0.997 0.003
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.001 0.997 0.002
D47.2 Monoclonal gammopathy
0.000 0.997 0.003
N08.4 Glomerular disorders in other endocrine, nutritional and metabolic diseases
0.000 0.997 0.003
A87 Viral meningitis
0.000 0.997 0.003
X43 Accidental poisoning by and exposure to other drugs acting on the autonomic nervous system
0.003 0.997 0.000
E73.8 Other lactose intolerance
0.000 0.997 0.002
E73.1 Secondary lactase deficiency
0.000 0.997 0.002
E73.0 Congenital lactase deficiency
0.000 0.997 0.002
B02.2 Zoster with other nervous system involvement
0.000 0.997 0.003
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.000 0.997 0.003
X49.9 Unspecified place
0.003 0.997 0.000
N08.8 Glomerular disorders in other diseases classified elsewhere
0.000 0.997 0.003
N08.2 Glomerular disorders in blood diseases and disorders involving the immune mechanism
0.000 0.997 0.003
N08.1 Glomerular disorders in neoplastic diseases
0.000 0.997 0.003
N08.0 Glomerular disorders in infectious and parasitic diseases classified elsewhere
0.000 0.997 0.003
M32 Systemic lupus erythematosus
0.000 0.997 0.003
M20-M25 Other joint disorders
0.000 0.997 0.003
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.997 0.002
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.997 0.002
E79.1 Lesch-Nyhan syndrome
0.000 0.997 0.002
K91.9 Postprocedural disorder of digestive system, unspecified
0.000 0.997 0.003
K91.1 Postgastric surgery syndromes
0.000 0.997 0.003
L08.8 Other specified local infections of skin and subcutaneous tissue
0.003 0.997 0.000
X47 Accidental poisoning by and exposure to other gases and vapours
0.003 0.997 0.000
D47.3 Essential (haemorrhagic) thrombocythaemia
0.000 0.997 0.003
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)
0.003 0.997 0.000
E70.3 Albinism
0.000 0.997 0.002
H11.4 Other conjunctival vascular disorders and cysts
0.003 0.997 0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.001 0.997 0.002
E70.8 Other disorders of aromatic amino-acid metabolism
0.001 0.997 0.002
E70.2 Disorders of tyrosine metabolism
0.001 0.997 0.002
E70.1 Other hyperphenylalaninaemias
0.001 0.997 0.002
E70.0 Classical phenylketonuria
0.001 0.997 0.002
L27.2 Dermatitis due to ingested food
0.000 0.997 0.002
M31 Other necrotising vasculopathies
0.000 0.997 0.003
A08.0 Rotaviral enteritis
0.000 0.997 0.002
E71.3 Disorders of fatty-acid metabolism
0.001 0.997 0.002
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.001 0.997 0.002
E71.1 Other disorders of branched-chain amino-acid metabolism
0.001 0.997 0.002
E71.0 Maple-syrup-urine disease
0.001 0.997 0.002
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.001 0.997 0.002
E76.8 Other disorders of glucosaminoglycan metabolism
0.001 0.997 0.002
E76.3 Mucopolysaccharidosis, unspecified
0.001 0.997 0.002
E76.2 Other mucopolysaccharidoses
0.001 0.997 0.002
E76.1 Mucopolysaccharidosis, type II
0.001 0.997 0.002
E76.0 Mucopolysaccharidosis, type I
0.001 0.997 0.002
E77.9 Disorder of glycoprotein metabolism, unspecified
0.001 0.997 0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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