TreeWAS – Variant ID: rs9258260

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E10.9 Without complications	0.000	0.012	0.988
E10 Insulin-dependent diabetes mellitus	0.000	0.013	0.987
E10.3 With ophthalmic complications	0.000	0.028	0.972
E10.1 With ketoacidosis	0.000	0.086	0.914
E10.4 With neurological complications	0.000	0.126	0.874
E10.5 With peripheral circulatory complications	0.000	0.192	0.808
E10.2 With renal complications	0.000	0.215	0.785
K90.0 Coeliac disease	0.000	0.217	0.783
E10.7 With multiple complications	0.000	0.293	0.707
E10.6 With other specified complications	0.000	0.293	0.707
E10.0 With coma	0.000	0.293	0.707
E10.8 With unspecified complications	0.000	0.295	0.704
K90 Intestinal malabsorption	0.000	0.574	0.426
E10-E14 Diabetes mellitus	0.000	0.599	0.401
E11 Non-insulin-dependent diabetes mellitus	0.000	0.669	0.331
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.671	0.329
E11.4 With neurological complications	0.000	0.688	0.312
K90.9 Intestinal malabsorption, unspecified	0.000	0.692	0.308
K90.8 Other intestinal malabsorption	0.000	0.694	0.306
K90.3 Pancreatic steatorrhoea	0.000	0.694	0.306
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.694	0.306
K90.1 Tropical sprue	0.000	0.694	0.306
E12 Malnutrition-related diabetes mellitus	0.000	0.712	0.288
E11.2 With renal complications	0.000	0.730	0.270
E11.8 With unspecified complications	0.000	0.740	0.260
E11.0 With coma	0.000	0.744	0.255
E13 Other specified diabetes mellitus	0.000	0.753	0.247
E11.5 With peripheral circulatory complications	0.000	0.756	0.244
E11.3 With ophthalmic complications	0.000	0.759	0.241
E11.7 With multiple complications	0.000	0.763	0.237
E11.6 With other specified complications	0.000	0.792	0.208
E12.9 Without complications	0.000	0.793	0.206
E12.8 With unspecified complications	0.000	0.793	0.206
E12.7 With multiple complications	0.000	0.793	0.206
E12.6 With other specified complications	0.000	0.793	0.206
E12.5 With peripheral circulatory complications	0.000	0.793	0.206
E12.4 With neurological complications	0.000	0.793	0.206
E12.3 With ophthalmic complications	0.000	0.793	0.206
E12.2 With renal complications	0.000	0.793	0.206
E12.1 With ketoacidosis	0.000	0.793	0.206
E12.0 With coma	0.000	0.793	0.206
E14 Unspecified diabetes mellitus	0.000	0.795	0.205
E13.8 With unspecified complications	0.000	0.823	0.177
E13.7 With multiple complications	0.000	0.823	0.177
E13.6 With other specified complications	0.000	0.823	0.177
E13.5 With peripheral circulatory complications	0.000	0.823	0.177
E13.4 With neurological complications	0.000	0.823	0.177
E13.3 With ophthalmic complications	0.000	0.823	0.177
E13.2 With renal complications	0.000	0.823	0.177
E13.1 With ketoacidosis	0.000	0.823	0.177
E13.0 With coma	0.000	0.823	0.177
E11.1 With ketoacidosis	0.000	0.823	0.176
E14.3 With ophthalmic complications	0.000	0.842	0.158
E14.8 With unspecified complications	0.000	0.853	0.147
E14.7 With multiple complications	0.000	0.853	0.147
E14.6 With other specified complications	0.000	0.853	0.147
E14.5 With peripheral circulatory complications	0.000	0.853	0.147
E14.2 Withrenal complications	0.000	0.853	0.147
E14.0 With coma	0.000	0.853	0.147
E14.4 With neurological complications	0.000	0.862	0.137
E13.9 Without complications	0.000	0.863	0.137
N60 Benign mammary dysplasia	0.130	0.870	0.000
E14.1 With ketoacidosis	0.000	0.874	0.126
N60.0 Solitary cyst of breast	0.124	0.876	0.000
N60.1 Diffuse cystic mastopathy	0.121	0.879	0.000
N60.3 Fibrosclerosis of breast	0.119	0.881	0.000
N60.4 Mammary duct ectasia	0.118	0.882	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.886	0.114
E70-E90 Metabolic disorders	0.000	0.892	0.108
E87 Other disorders of fluid, electrolyte and acid-base balance	0.000	0.897	0.103
K90-K93 Other diseases of the digestive system	0.000	0.898	0.102
E88 Other metabolic disorders	0.000	0.900	0.100
N60-N64 Disorders of breast	0.098	0.902	0.000
N62 Hypertrophy of breast	0.098	0.902	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.000	0.903	0.097
N60.8 Other benign mammary dysplasias	0.096	0.904	0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.000	0.904	0.096
N60.2 Fibroadenosis of breast	0.095	0.904	0.000
E87.5 Hyperkalaemia	0.000	0.905	0.095
E14.9 Without complications	0.000	0.906	0.094
N60.9 Benign mammary dysplasia, unspecified	0.093	0.907	0.000
E83.1 Disorders of iron metabolism	0.000	0.907	0.093
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.909	0.091
E73 Lactose intolerance	0.000	0.909	0.091
E83 Disorders of mineral metabolism	0.000	0.909	0.091
E87.1 Hypo-osmolality and hyponatraemia	0.000	0.910	0.090
E80.4 Gilbert's syndrome	0.000	0.911	0.089
E87.3 Alkalosis	0.000	0.913	0.087
E87.7 Fluid overload	0.000	0.915	0.085
N64 Other disorders of breast	0.084	0.916	0.000
E85 Amyloidosis	0.000	0.918	0.081
E73.9 Lactose intolerance, unspecified	0.000	0.922	0.078
E87.0 Hyperosmolality and hypernatraemia	0.000	0.922	0.078
E84 Cystic fibrosis	0.000	0.922	0.078
E79 Disorders of purine and pyrimidine metabolism	0.000	0.922	0.078
E77 Disorders of glycoprotein metabolism	0.000	0.922	0.078
E76 Disorders of glycosaminoglycan metabolism	0.000	0.922	0.078
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.000	0.922	0.078
E72 Other disorders of amino-acid metabolism	0.000	0.922	0.078
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.000	0.922	0.078
E70 Disorders of aromatic amino-acid metabolism	0.000	0.922	0.078
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.000	0.922	0.078
N64.9 Disorder of breast, unspecified	0.076	0.924	0.000
E16 Other disorders of pancreatic internal secretion	0.000	0.925	0.075
J32.9 Chronic sinusitis, unspecified	0.075	0.925	0.000
K92 Other diseases of digestive system	0.000	0.925	0.075
E74 Other disorders of carbohydrate metabolism	0.000	0.925	0.075
E87.4 Mixed disorder of acid-base balance	0.000	0.926	0.074
E87.6 Hypokalaemia	0.000	0.926	0.074
K93 Disorders of other digestive organs in diseases classified elsewhere	0.000	0.927	0.073
J32 Chronic sinusitis	0.072	0.928	0.000
E88.9 Metabolic disorder, unspecified	0.000	0.928	0.071
E88.8 Other specified metabolic disorders	0.000	0.928	0.071
E88.2 Lipomatosis, not elsewhere classified	0.000	0.928	0.071
E88.1 Lipodystrophy, not elsewhere classified	0.000	0.928	0.071
N64.1 Fat necrosis of breast	0.071	0.929	0.000
E40-E46 Malnutrition	0.000	0.929	0.070
E80.7 Disorder of bilirubin metabolism, unspecified	0.000	0.930	0.070
E80.6 Other disorders of bilirubin metabolism	0.000	0.930	0.070
E80.5 Crigler-Najjar syndrome	0.000	0.930	0.070
E80.3 Defects of catalase and peroxydase	0.000	0.930	0.070
E80.2 Other porphyria	0.000	0.930	0.070
E80.1 Porphyria cutanea tarda	0.000	0.930	0.070
E80.0 Hereditary erythropoietic porphyria	0.000	0.930	0.070
E20-E35 Disorders of other endocrine glands	0.000	0.930	0.070
K92.9 Disease of digestive system, unspecified	0.000	0.931	0.069
J32.2 Chronic ethmoidal sinusitis	0.068	0.932	0.000
E16.2 Hypoglycaemia, unspecified	0.000	0.933	0.067
K92.1 Melaena	0.000	0.934	0.066
E15 Nondiabetic hypoglycaemic coma	0.000	0.934	0.066
J32.4 Chronic pansinusitis	0.065	0.935	0.000
E73.8 Other lactose intolerance	0.000	0.935	0.065
E73.1 Secondary lactase deficiency	0.000	0.935	0.065
E73.0 Congenital lactase deficiency	0.000	0.935	0.065
E83.9 Disorder of mineral metabolism, unspecified	0.000	0.935	0.065
E83.8 Other disorders of mineral metabolism	0.000	0.935	0.065
E83.2 Disorders of zinc metabolism	0.000	0.935	0.065
E83.0 Disorders of copper metabolism	0.000	0.935	0.065
N64.4 Mastodynia	0.064	0.936	0.000
E50-E64 Other nutritional deficiencies	0.000	0.937	0.063
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.938	0.062
E85.9 Amyloidosis, unspecified	0.000	0.938	0.062
E88.3 Tumour lysis syndrome	0.000	0.939	0.061
N64.3 Galactorrhoea not associated with childbirth	0.060	0.940	0.000
N64.2 Atrophy of breast	0.060	0.940	0.000
N64.0 Fissure and fistula of nipple	0.060	0.940	0.000
E85.4 Organ-limited amyloidosis	0.000	0.940	0.059
E85.8 Other amyloidosis	0.000	0.941	0.059
E85.3 Secondary systemic amyloidosis	0.000	0.941	0.059
E85.2 Heredofamilial amyloidosis, unspecified	0.000	0.941	0.059
E85.1 Neuropathic heredofamilial amyloidosis	0.000	0.941	0.059
E85.0 Nonneuropathic heredofamilial amyloidosis	0.000	0.941	0.059
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.000	0.942	0.058
J32.1 Chronic frontal sinusitis	0.058	0.942	0.000
L03.1 Cellulitis of other parts of limb	0.000	0.942	0.058
K92.8 Other specified diseases of digestive system	0.000	0.944	0.056
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.000	0.944	0.056
E70.8 Other disorders of aromatic amino-acid metabolism	0.000	0.944	0.056
E70.3 Albinism	0.000	0.944	0.056
E70.2 Disorders of tyrosine metabolism	0.000	0.944	0.056
E70.1 Other hyperphenylalaninaemias	0.000	0.944	0.056
E70.0 Classical phenylketonuria	0.000	0.944	0.056
E71.3 Disorders of fatty-acid metabolism	0.000	0.944	0.056
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.000	0.944	0.056
E71.1 Other disorders of branched-chain amino-acid metabolism	0.000	0.944	0.056
E71.0 Maple-syrup-urine disease	0.000	0.944	0.056
E72.9 Disorder of amino-acid metabolism, unspecified	0.000	0.944	0.056
E72.8 Other specified disorders of amino-acid metabolism	0.000	0.944	0.056
E72.5 Disorders of glycine metabolism	0.000	0.944	0.056
E72.4 Disorders of ornithine metabolism	0.000	0.944	0.056
E72.3 Disorders of lysine and hydroxylysine metabolism	0.000	0.944	0.056
E72.2 Disorders of urea cycle metabolism	0.000	0.944	0.056
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.000	0.944	0.056
E72.0 Disorders of amino-acid transport	0.000	0.944	0.056
E75.6 Lipid storage disorder, unspecified	0.000	0.944	0.056
E75.5 Other lipid storage disorders	0.000	0.944	0.056
E75.4 Neuronal ceroid lipofuscinosis	0.000	0.944	0.056
E75.3 Sphingolipidosis, unspecified	0.000	0.944	0.056
E75.2 Other sphingolipidosis	0.000	0.944	0.056
E75.1 Other gangliosidosis	0.000	0.944	0.056
E75.0 GM2 gangliosidosis	0.000	0.944	0.056
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.000	0.944	0.056
E76.8 Other disorders of glucosaminoglycan metabolism	0.000	0.944	0.056
E76.3 Mucopolysaccharidosis, unspecified	0.000	0.944	0.056
E76.2 Other mucopolysaccharidoses	0.000	0.944	0.056
E76.1 Mucopolysaccharidosis, type II	0.000	0.944	0.056
E76.0 Mucopolysaccharidosis, type I	0.000	0.944	0.056
E77.9 Disorder of glycoprotein metabolism, unspecified	0.000	0.944	0.056
E77.8 Other disorders of glycoprotein metabolism	0.000	0.944	0.056
E77.1 Defects in glycoprotein degradation	0.000	0.944	0.056
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.000	0.944	0.056
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.000	0.944	0.056
E79.8 Other disorders of purine and pyrimidine metabolism	0.000	0.944	0.056
E79.1 Lesch-Nyhan syndrome	0.000	0.944	0.056
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.000	0.944	0.056
E84.9 Cystic fibrosis, unspecified	0.000	0.944	0.056
E84.8 Cystic fibrosis with other manifestations	0.000	0.944	0.056
E84.1 Cystic fibrosis with intestinal manifestations	0.000	0.944	0.056
E84.0 Cystic fibrosis with pulmonary manifestations	0.000	0.944	0.056
E27 Other disorders of adrenal gland	0.000	0.944	0.056
J32.0 Chronic maxillary sinusitis	0.055	0.945	0.000
E28 Ovarian dysfunction	0.000	0.945	0.055
E21.0 Primary hyperparathyroidism	0.000	0.945	0.055
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.946	0.054
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.946	0.054
E16.4 Abnormal secretion of gastrin	0.000	0.946	0.054
E16.3 Increased secretion of glucagon	0.000	0.946	0.054
E16.1 Other hypoglycaemia	0.000	0.946	0.054
E74.9 Disorder of carbohydrate metabolism, unspecified	0.000	0.946	0.054
E74.8 Other specified disorders of carbohydrate metabolism	0.000	0.946	0.054
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.000	0.946	0.054
E74.2 Disorders of galactose metabolism	0.000	0.946	0.054
E74.1 Disorders of fructose metabolism	0.000	0.946	0.054
E74.0 Glycogen storage disease	0.000	0.946	0.054
E21.3 Hyperparathyroidism, unspecified	0.000	0.947	0.053
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere	0.000	0.947	0.053
K93.1 Megacolon in Chagas' disease	0.000	0.947	0.053
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands	0.000	0.947	0.053
E65-E68 Obesity and other hyperalimentation	0.000	0.947	0.053
J32.3 Chronic sphenoidal sinusitis	0.052	0.948	0.000
E74.3 Other disorders of intestinal carbohydrate absorption	0.000	0.949	0.051
J32.8 Other chronic sinusitis	0.051	0.949	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.949	0.051
E45 Retarded development following protein-energy malnutrition	0.000	0.949	0.051
E43 Unspecified severe protein-energy malnutrition	0.000	0.949	0.051
E42 Marasmic kwashiorkor	0.000	0.949	0.051
E41 Nutritional marasmus	0.000	0.949	0.051
E40 Kwashiorkor	0.000	0.949	0.051
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.950	0.050
E32 Diseases of thymus	0.000	0.950	0.050
E31 Polyglandular dysfunction	0.000	0.950	0.050
E30 Disorders of puberty, not elsewhere classified	0.000	0.950	0.050
E25 Adrenogenital disorders	0.000	0.950	0.050
N64.8 Other specified disorders of breast	0.050	0.950	0.000
E20 Hypoparathyroidism	0.000	0.950	0.050
E34 Other endocrine disorders	0.000	0.950	0.050
E27.1 Primary adrenocortical insufficiency	0.000	0.951	0.048
E29 Testicular dysfunction	0.000	0.953	0.047
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.953	0.047
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.954	0.045
E63 Other nutritional deficiencies	0.000	0.954	0.045
E56 Other vitamin deficiencies	0.000	0.954	0.045
E51 Thiamine deficiency	0.000	0.954	0.045
E50 Vitamin A deficiency	0.000	0.954	0.045
E60 Dietary zinc deficiency	0.000	0.954	0.045
E59 Dietary selenium deficiency	0.000	0.954	0.045
E58 Dietary calcium deficiency	0.000	0.954	0.045
E54 Ascorbic acid deficiency	0.000	0.954	0.045
E52 Niacin deficiency [pellagra]	0.000	0.954	0.045
E24 Cushing's syndrome	0.000	0.954	0.045
E28.2 Polycystic ovarian syndrome	0.000	0.955	0.045
E83.4 Disorders of magnesium metabolism	0.000	0.955	0.045
E21.5 Disorder of parathyroid gland, unspecified	0.000	0.955	0.045
E21.4 Other specified disorders of parathyroid gland	0.000	0.955	0.045
E21.2 Other hyperparathyroidism	0.000	0.955	0.045
E61 Deficiency of other nutrient elements	0.000	0.956	0.044
E27.8 Other specified disorders of adrenal gland	0.000	0.956	0.043
E26 Hyperaldosteronism	0.000	0.958	0.041
E27.5 Adrenomedullary hyperfunction	0.000	0.960	0.040
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.960	0.040
E27.0 Other adrenocortical overactivity	0.000	0.960	0.040
E53 Deficiency of other B group vitamins	0.000	0.960	0.040
I20.9 Angina pectoris, unspecified	0.040	0.960	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.000	0.960	0.040
E28.9 Ovarian dysfunction, unspecified	0.000	0.960	0.040
E28.8 Other ovarian dysfunction	0.000	0.960	0.040
E28.3 Primary ovarian failure	0.000	0.960	0.040
E28.1 Androgen excess	0.000	0.960	0.040
E28.0 Oestrogen excess	0.000	0.960	0.040
E46 Unspecified protein-energy malnutrition	0.000	0.960	0.040
N61 Inflammatory disorders of breast	0.040	0.960	0.000
N64.5 Other signs and symptoms in breast	0.039	0.960	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.961	0.039
E27.2 Addisonian crisis	0.000	0.962	0.038
E67 Other hyperalimentation	0.000	0.962	0.038
E68 Sequelae of hyperalimentation	0.000	0.962	0.038
E65 Localised adiposity	0.000	0.962	0.038
E83.3 Disorders of phosphorus metabolism	0.000	0.962	0.037
E55 Vitamin D deficiency	0.000	0.963	0.037
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.000	0.963	0.037
E44.1 Mild protein-energy malnutrition	0.000	0.963	0.036
E44.0 Moderate protein-energy malnutrition	0.000	0.963	0.036
E25.9 Adrenogenital disorder, unspecified	0.000	0.964	0.036
E25.8 Other adrenogenital disorders	0.000	0.964	0.036
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.964	0.036
E30.9 Disorder of puberty, unspecified	0.000	0.964	0.036
E30.8 Other disorders of puberty	0.000	0.964	0.036
E30.1 Precocious puberty	0.000	0.964	0.036
E30.0 Delayed puberty	0.000	0.964	0.036
E31.9 Polyglandular dysfunction, unspecified	0.000	0.964	0.036
E31.8 Other polyglandular dysfunction	0.000	0.964	0.036
E31.1 Polyglandular hyperfunction	0.000	0.964	0.036
E31.0 Autoimmune polyglandular failure	0.000	0.964	0.036
E32.9 Disease of thymus, unspecified	0.000	0.964	0.036
E32.8 Other diseases of thymus	0.000	0.964	0.036
E32.1 Abscess of thymus	0.000	0.964	0.036
E32.0 Persistent hyperplasia of thymus	0.000	0.964	0.036
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.964	0.036
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.964	0.036
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.964	0.036
E20.8 Other hypoparathyroidism	0.000	0.964	0.036
E20.1 Pseudohypoparathyroidism	0.000	0.964	0.036
E20.0 Idiopathic hypoparathyroidism	0.000	0.964	0.036
E34.8 Other specified endocrine disorders	0.000	0.964	0.036
E34.5 Androgen resistance syndrome	0.000	0.964	0.036
E34.4 Constitutional tall stature	0.000	0.964	0.036
E34.3 Short stature, not elsewhere classified	0.000	0.964	0.036
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.964	0.036
E34.1 Other hypersecretion of intestinal hormones	0.000	0.964	0.036
E34.0 Carcinoid syndrome	0.000	0.964	0.036
E27.9 Disorder of adrenal gland, unspecified	0.000	0.964	0.036
E00-E07 Disorders of thyroid gland	0.000	0.964	0.036
E20.9 Hypoparathyroidism, unspecified	0.000	0.965	0.035
E34.9 Endocrine disorder, unspecified	0.000	0.965	0.035
E22 Hyperfunction of pituitary gland	0.000	0.965	0.034
E29.9 Testicular dysfunction, unspecified	0.000	0.966	0.034
E29.8 Other testicular dysfunction	0.000	0.966	0.034
E29.0 Testicular hyperfunction	0.000	0.966	0.034
I20.8 Other forms of angina pectoris	0.034	0.966	0.000
E50.9 Vitamin A deficiency, unspecified	0.000	0.967	0.033
E50.8 Other manifestations of vitamin A deficiency	0.000	0.967	0.033
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.967	0.033
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.967	0.033
E50.5 Vitamin A deficiency with night blindness	0.000	0.967	0.033
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.967	0.033
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.967	0.033
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.967	0.033
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.967	0.033
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.967	0.033
E51.9 Thiamine deficiency, unspecified	0.000	0.967	0.033
E51.8 Other manifestations of thiamine deficiency	0.000	0.967	0.033
E51.2 Wernicke's encephalopathy	0.000	0.967	0.033
E51.1 Beriberi	0.000	0.967	0.033
E56.9 Vitamin deficiency, unspecified	0.000	0.967	0.033
E56.8 Deficiency of other vitamins	0.000	0.967	0.033
E56.1 Deficiency of vitamin K	0.000	0.967	0.033
E56.0 Deficiency of vitamin E	0.000	0.967	0.033
E63.9 Nutritional deficiency, unspecified	0.000	0.967	0.033
E63.8 Other specified nutritional deficiencies	0.000	0.967	0.033
E63.1 Imbalance of constituents of food intake	0.000	0.967	0.033
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.967	0.033
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.967	0.033
E64.8 Sequelae of other nutritional deficiencies	0.000	0.967	0.033
E64.3 Sequelae of rickets	0.000	0.967	0.033
E64.2 Sequelae of vitamin C deficiency	0.000	0.967	0.033
E64.1 Sequelae of vitamin A deficiency	0.000	0.967	0.033
E64.0 Sequelae of protein-energy malnutrition	0.000	0.967	0.033
E24.8 Other Cushing's syndrome	0.000	0.967	0.033
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.967	0.033
E24.3 Ectopic ACTH syndrome	0.000	0.967	0.033
E24.2 Drug-induced Cushing's syndrome	0.000	0.967	0.033
E24.1 Nelson's syndrome	0.000	0.967	0.033
E24.0 Pituitary-dependent Cushing's disease	0.000	0.967	0.033
I20 Angina pectoris	0.032	0.968	0.000
E61.9 Deficiency of nutrient element, unspecified	0.000	0.968	0.032
E61.8 Deficiency of other specified nutrient elements	0.000	0.968	0.032
E61.7 Deficiency of multiple nutrient elements	0.000	0.968	0.032
E61.6 Vanadium deficiency	0.000	0.968	0.032
E61.5 Molybdenum deficiency	0.000	0.968	0.032
E61.4 Chromium deficiency	0.000	0.968	0.032
E61.3 Manganese deficiency	0.000	0.968	0.032
E61.2 Magnesium deficiency	0.000	0.968	0.032
E61.0 Copper deficiency	0.000	0.968	0.032
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.000	0.968	0.032
E29.1 Testicular hypofunction	0.000	0.969	0.031
E61.1 Iron deficiency	0.000	0.970	0.030
E23 Hypofunction and other disorders of pituitary gland	0.000	0.970	0.030
E26.9 Hyperaldosteronism, unspecified	0.000	0.970	0.030
E26.8 Other hyperaldosteronism	0.000	0.970	0.030
E26.1 Secondary hyperaldosteronism	0.000	0.970	0.030
E53.1 Pyridoxine deficiency	0.000	0.971	0.029
E53.0 Riboflavin deficiency	0.000	0.971	0.029
E89.3 Postprocedural hypopituitarism	0.000	0.971	0.029
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.000	0.971	0.029
E89.8 Other postprocedural endocrine and metabolic disorders	0.000	0.971	0.029
E89.5 Postprocedural testicular hypofunction	0.000	0.971	0.029
E89.4 Postprocedural ovarian failure	0.000	0.971	0.029
E89.1 Postprocedural hypoinsulinaemia	0.000	0.971	0.029
E53.8 Deficiency of other specified B group vitamins	0.000	0.971	0.029
E24.9 Cushing's syndrome, unspecified	0.000	0.972	0.028
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.972	0.028
E67.8 Other specified hyperalimentation	0.000	0.973	0.027
E67.3 Hypervitaminosis D	0.000	0.973	0.027
E67.2 Megavitamin-B6 syndrome	0.000	0.973	0.027
E67.1 Hypercarotenaemia	0.000	0.973	0.027
E67.0 Hypervitaminosis A	0.000	0.973	0.027
N63 Unspecified lump in breast	0.027	0.973	0.000
E89.2 Postprocedural hypoparathyroidism	0.000	0.973	0.027
E55.0 Rickets, active	0.000	0.973	0.027
E83.5 Disorders of calcium metabolism	0.000	0.973	0.026
E07 Other disorders of thyroid	0.000	0.974	0.026
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.974	0.026
E00 Congenital iodine-deficiency syndrome	0.000	0.974	0.026
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.974	0.026
E87.2 Acidosis	0.000	0.974	0.025
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.975	0.025
E22.8 Other hyperfunction of pituitary gland	0.000	0.975	0.025
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.000	0.975	0.025
E53.9 Vitamin B deficiency, unspecified	0.000	0.975	0.024
K92.2 Gastro-intestinal haemorrhage, unspecified	0.000	0.976	0.024
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.977	0.023
K91.9 Postprocedural disorder of digestive system, unspecified	0.000	0.977	0.023
K91.5 Postcholecystectomy syndrome	0.000	0.977	0.023
E04 Other non-toxic goitre	0.000	0.977	0.023
K91.0 Vomiting following gastro-intestinal surgery	0.000	0.977	0.022
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.000	0.978	0.022
K91.3 Postoperative intestinal obstruction	0.000	0.978	0.022
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.978	0.022
E23.1 Drug-induced hypopituitarism	0.000	0.978	0.022
E23.6 Other disorders of pituitary gland	0.000	0.978	0.021
E22.0 Acromegaly and pituitary gigantism	0.000	0.978	0.021
E22.1 Hyperprolactinaemia	0.000	0.978	0.021
E26.0 Primary hyperaldosteronism	0.001	0.979	0.021
K91.1 Postgastric surgery syndromes	0.000	0.979	0.021
K91.2 Postsurgical malabsorption, not elsewhere classified	0.000	0.979	0.021
E23.7 Disorder of pituitary gland, unspecified	0.000	0.979	0.020
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.979	0.020
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.979	0.020
E07.8 Other specified disorders of thyroid	0.000	0.980	0.020
E05.8 Other thyrotoxicosis	0.000	0.980	0.020
E05.5 Thyroid crisis or storm	0.000	0.980	0.020
E05.4 Thyrotoxicosis factitia	0.000	0.980	0.020
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.980	0.020
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.980	0.020
E04.1 Non-toxic single thyroid nodule	0.000	0.980	0.020
I20.0 Unstable angina	0.019	0.981	0.000
E07.1 Dyshormogenetic goitre	0.000	0.981	0.019
E07.0 Hypersecretion of calcitonin	0.000	0.981	0.019
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.981	0.019
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.981	0.019
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.981	0.019
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.981	0.019
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.981	0.019
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.981	0.019
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.981	0.019
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.981	0.019
E55.9 Vitamin D deficiency, unspecified	0.000	0.981	0.018
E05.9 Thyrotoxicosis, unspecified	0.000	0.982	0.018
E23.2 Diabetes insipidus	0.000	0.982	0.018
E07.9 Disorder of thyroid, unspecified	0.000	0.983	0.017
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.002	0.983	0.015
E86 Volume depletion	0.000	0.983	0.017
E04.8 Other specified non-toxic goitre	0.000	0.984	0.016
E04.2 Non-toxic multinodular goitre	0.000	0.984	0.016
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.000	0.984	0.016
I20.1 Angina pectoris with documented spasm	0.016	0.984	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.000	0.985	0.015
E04.0 Non-toxic diffuse goitre	0.000	0.986	0.014
C85.1 B-cell lymphoma, unspecified	0.000	0.986	0.014
E06 Thyroiditis	0.001	0.986	0.013
E78.8 Other disorders of lipoprotein metabolism	0.001	0.986	0.013
E78.0 Pure hypercholesterolaemia	0.014	0.986	0.000
K92.0 Haematemesis	0.000	0.987	0.013
K91.4 Colostomy and enterostomy malfunction	0.000	0.987	0.013
E23.0 Hypopituitarism	0.000	0.987	0.012
J30-J39 Other diseases of upper respiratory tract	0.013	0.987	0.000
E78.1 Pure hyperglyceridaemia	0.001	0.987	0.011
E78.6 Lipoprotein deficiency	0.002	0.987	0.011
E78.3 Hyperchylomicronaemia	0.002	0.987	0.011
J31.0 Chronic rhinitis	0.012	0.988	0.000
E78.2 Mixed hyperlipidaemia	0.001	0.988	0.011
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.012	0.988	0.000
J34.8 Other specified disorders of nose and nasal sinuses	0.012	0.988	0.000
E78.4 Other hyperlipidaemia	0.002	0.988	0.010
E03 Other hypothyroidism	0.000	0.989	0.011
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.000	0.989	0.011
C85.0 Lymphosarcoma	0.000	0.989	0.011
J37 Chronic laryngitis and laryngotracheitis	0.011	0.989	0.000
J34 Other disorders of nose and nasal sinuses	0.010	0.990	0.000
E06.5 Other chronic thyroiditis	0.001	0.990	0.010
E06.4 Drug-induced thyroiditis	0.001	0.990	0.010
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.001	0.990	0.010
E06.1 Subacute thyroiditis	0.001	0.990	0.010
E06.0 Acute thyroiditis	0.001	0.990	0.010
C85.7 Other specified types of non-Hodgkin's lymphoma	0.000	0.990	0.010
J30 Vasomotor and allergic rhinitis	0.010	0.990	0.000
J37.0 Chronic laryngitis	0.009	0.990	0.000
E89.0 Postprocedural hypothyroidism	0.000	0.990	0.009
E66 Obesity	0.000	0.991	0.009
J31.1 Chronic nasopharyngitis	0.009	0.991	0.000
E78.9 Disorder of lipoprotein metabolism, unspecified	0.002	0.991	0.007
E03.5 Myxoedema coma	0.000	0.992	0.008
E03.4 Atrophy of thyroid (acquired)	0.000	0.992	0.008
E03.3 Postinfectious hypothyroidism	0.000	0.992	0.008
E03.1 Congenital hypothyroidism without goitre	0.000	0.992	0.008
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.992	0.008
J34.3 Hypertrophy of nasal turbinates	0.008	0.992	0.000
E04.9 Non-toxic goitre, unspecified	0.000	0.992	0.008
J37.1 Chronic laryngotracheitis	0.008	0.992	0.000
J30.3 Other allergic rhinitis	0.008	0.992	0.000
K83.8 Other specified diseases of biliary tract	0.008	0.992	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.992	0.007
E03.8 Other specified hypothyroidism	0.000	0.992	0.007
J30.4 Allergic rhinitis, unspecified	0.007	0.992	0.000
J36 Peritonsillar abscess	0.007	0.993	0.000
E06.9 Thyroiditis, unspecified	0.001	0.993	0.006
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.007	0.993	0.000
J30.2 Other seasonal allergic rhinitis	0.007	0.993	0.000
J30.0 Vasomotor rhinitis	0.007	0.993	0.000
E66.2 Extreme obesity with alveolar hypoventilation	0.000	0.993	0.007

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations