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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs9261389
log Bayes Factor = 28.7141
Chromosome 6   position 30,061,555  (GRCh37) Explore rs9261389 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
L40.5 Arthropathic psoriasis
1.000 0.000 0.000
L40 Psoriasis
1.000 0.000 0.000
E03.9 Hypothyroidism, unspecified
0.000 0.002 0.998
E03 Other hypothyroidism
0.000 0.010 0.990
E00-E07 Disorders of thyroid gland
0.000 0.014 0.986
K51.9 Ulcerative colitis, unspecified
0.000 0.031 0.969
K51 Ulcerative colitis
0.000 0.037 0.963
E10 Insulin-dependent diabetes mellitus
0.000 0.057 0.943
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.068 0.932
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.074 0.926
E10-E14 Diabetes mellitus
0.000 0.074 0.926
E06 Thyroiditis
0.000 0.080 0.920
E10.1 With ketoacidosis
0.000 0.082 0.918
K51.0 Ulcerative (chronic) enterocolitis
0.000 0.088 0.912
L40.0 Psoriasis vulgaris
0.908 0.092 0.000
K51.4 Pseudopolyposis of colon
0.000 0.096 0.904
E06.3 Autoimmune thyroiditis
0.000 0.114 0.886
E10.3 With ophthalmic complications
0.000 0.115 0.885
E05.9 Thyrotoxicosis, unspecified
0.000 0.116 0.884
K51.8 Other ulcerative colitis
0.000 0.119 0.881
E10.5 With peripheral circulatory complications
0.000 0.139 0.861
E10.9 Without complications
0.000 0.139 0.861
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.145 0.855
K51.5 Mucosal proctocolitis
0.000 0.159 0.841
E10.4 With neurological complications
0.000 0.171 0.829
E10.2 With renal complications
0.000 0.186 0.814
K51.2 Ulcerative (chronic) proctitis
0.000 0.196 0.804
L40.8 Other psoriasis
0.789 0.211 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.213 0.787
E04 Other non-toxic goitre
0.000 0.251 0.749
E03.8 Other specified hypothyroidism
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.717 0.283 0.000
L40.3 Pustulosis palmaris et plantaris
0.717 0.283 0.000
L40.2 Acrodermatitis continua
0.717 0.283 0.000
E20-E35 Disorders of other endocrine glands
0.000 0.289 0.711
E13 Other specified diabetes mellitus
0.000 0.289 0.711
E03.5 Myxoedema coma
0.000 0.290 0.710
E03.4 Atrophy of thyroid (acquired)
0.000 0.290 0.710
E03.3 Postinfectious hypothyroidism
0.000 0.290 0.710
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.290 0.710
E10.0 With coma
0.000 0.291 0.709
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.293 0.707
E00 Congenital iodine-deficiency syndrome
0.000 0.293 0.707
L40.1 Generalised pustular psoriasis
0.704 0.295 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.309 0.691
E16 Other disorders of pancreatic internal secretion
0.000 0.313 0.687
K51.1 Ulcerative (chronic) ileocolitis
0.000 0.320 0.680
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.322 0.678
E10.6 With other specified complications
0.000 0.322 0.678
E10.7 With multiple complications
0.000 0.324 0.676
E05.5 Thyroid crisis or storm
0.000 0.332 0.668
E05.4 Thyrotoxicosis factitia
0.000 0.332 0.668
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.332 0.668
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.332 0.668
E12 Malnutrition-related diabetes mellitus
0.000 0.336 0.664
K90 Intestinal malabsorption
0.000 0.336 0.664
E06.5 Other chronic thyroiditis
0.000 0.341 0.659
E06.4 Drug-induced thyroiditis
0.000 0.341 0.659
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.341 0.659
E06.0 Acute thyroiditis
0.000 0.341 0.659
E06.9 Thyroiditis, unspecified
0.000 0.346 0.654
E34 Other endocrine disorders
0.000 0.355 0.645
E04.1 Non-toxic single thyroid nodule
0.000 0.358 0.642
E03.1 Congenital hypothyroidism without goitre
0.000 0.362 0.638
E07 Other disorders of thyroid
0.000 0.365 0.635
E16.2 Hypoglycaemia, unspecified
0.000 0.381 0.619
E27 Other disorders of adrenal gland
0.000 0.382 0.618
E40-E46 Malnutrition
0.000 0.391 0.609
E22 Hyperfunction of pituitary gland
0.000 0.404 0.596
K90.9 Intestinal malabsorption, unspecified
0.000 0.413 0.587
E04.9 Non-toxic goitre, unspecified
0.000 0.418 0.582
E27.1 Primary adrenocortical insufficiency
0.000 0.423 0.577
E05.8 Other thyrotoxicosis
0.000 0.434 0.565
E06.1 Subacute thyroiditis
0.000 0.436 0.564
E15 Nondiabetic hypoglycaemic coma
0.000 0.436 0.564
E10.8 With unspecified complications
0.000 0.437 0.563
E24 Cushing's syndrome
0.000 0.443 0.557
E13.9 Without complications
0.000 0.444 0.556
E04.0 Non-toxic diffuse goitre
0.000 0.445 0.555
E20 Hypoparathyroidism
0.000 0.445 0.555
K51.3 Ulcerative (chronic) rectosigmoiditis
0.000 0.448 0.552
E34.9 Endocrine disorder, unspecified
0.000 0.450 0.549
E34.8 Other specified endocrine disorders
0.000 0.454 0.546
E04.8 Other specified non-toxic goitre
0.000 0.463 0.537
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.483 0.517
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.490 0.510
E32 Diseases of thymus
0.000 0.490 0.510
E31 Polyglandular dysfunction
0.000 0.490 0.510
E30 Disorders of puberty, not elsewhere classified
0.000 0.490 0.510
E13.8 With unspecified complications
0.000 0.490 0.509
E13.7 With multiple complications
0.000 0.490 0.509
E13.6 With other specified complications
0.000 0.490 0.509
E13.5 With peripheral circulatory complications
0.000 0.490 0.509
E13.4 With neurological complications
0.000 0.490 0.509
E13.3 With ophthalmic complications
0.000 0.490 0.509
E13.2 With renal complications
0.000 0.490 0.509
E13.1 With ketoacidosis
0.000 0.490 0.509
E13.0 With coma
0.000 0.490 0.509
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.493 0.507
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.493 0.507
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.493 0.507
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.493 0.507
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.493 0.507
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.493 0.507
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.493 0.507
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.493 0.507
E22.0 Acromegaly and pituitary gigantism
0.000 0.495 0.505
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.498 0.502
E25 Adrenogenital disorders
0.000 0.501 0.499
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.507 0.493
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.507 0.493
E16.4 Abnormal secretion of gastrin
0.000 0.507 0.493
E16.3 Increased secretion of glucagon
0.000 0.507 0.493
E29 Testicular dysfunction
0.000 0.513 0.487
E34.0 Carcinoid syndrome
0.000 0.519 0.481
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.520 0.480
E12.9 Without complications
0.000 0.524 0.476
E12.8 With unspecified complications
0.000 0.524 0.476
E12.7 With multiple complications
0.000 0.524 0.476
E12.6 With other specified complications
0.000 0.524 0.476
E12.5 With peripheral circulatory complications
0.000 0.524 0.476
E12.4 With neurological complications
0.000 0.524 0.476
E12.3 With ophthalmic complications
0.000 0.524 0.476
E12.2 With renal complications
0.000 0.524 0.476
E12.1 With ketoacidosis
0.000 0.524 0.476
E12.0 With coma
0.000 0.524 0.476
K90.3 Pancreatic steatorrhoea
0.000 0.524 0.476
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.524 0.476
K90.1 Tropical sprue
0.000 0.524 0.476
E27.8 Other specified disorders of adrenal gland
0.000 0.532 0.468
E34.5 Androgen resistance syndrome
0.000 0.537 0.463
E34.4 Constitutional tall stature
0.000 0.537 0.463
E34.3 Short stature, not elsewhere classified
0.000 0.537 0.463
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.537 0.463
E34.1 Other hypersecretion of intestinal hormones
0.000 0.537 0.463
E22.1 Hyperprolactinaemia
0.000 0.538 0.462
E24.9 Cushing's syndrome, unspecified
0.000 0.538 0.462
E65-E68 Obesity and other hyperalimentation
0.000 0.543 0.457
E07.1 Dyshormogenetic goitre
0.000 0.544 0.455
E07.0 Hypersecretion of calcitonin
0.000 0.544 0.455
E16.1 Other hypoglycaemia
0.000 0.546 0.454
K90.8 Other intestinal malabsorption
0.000 0.551 0.449
E20.9 Hypoparathyroidism, unspecified
0.000 0.556 0.444
E27.5 Adrenomedullary hyperfunction
0.000 0.556 0.443
E27.0 Other adrenocortical overactivity
0.000 0.556 0.443
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.560 0.440
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.563 0.437
E45 Retarded development following protein-energy malnutrition
0.000 0.563 0.437
E43 Unspecified severe protein-energy malnutrition
0.000 0.563 0.437
E42 Marasmic kwashiorkor
0.000 0.563 0.437
E41 Nutritional marasmus
0.000 0.563 0.437
E40 Kwashiorkor
0.000 0.563 0.437
E28 Ovarian dysfunction
0.000 0.564 0.436
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.573 0.427
E22.8 Other hyperfunction of pituitary gland
0.000 0.573 0.427
E07.8 Other specified disorders of thyroid
0.000 0.576 0.424
E07.9 Disorder of thyroid, unspecified
0.000 0.579 0.421
E27.2 Addisonian crisis
0.000 0.584 0.416
E26 Hyperaldosteronism
0.000 0.590 0.410
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.001 0.595 0.404
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.598 0.402
E24.8 Other Cushing's syndrome
0.000 0.601 0.399
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.601 0.399
E24.3 Ectopic ACTH syndrome
0.000 0.601 0.399
E24.2 Drug-induced Cushing's syndrome
0.000 0.601 0.399
E24.1 Nelson's syndrome
0.000 0.601 0.399
E20.8 Other hypoparathyroidism
0.000 0.602 0.398
E20.1 Pseudohypoparathyroidism
0.000 0.602 0.398
E20.0 Idiopathic hypoparathyroidism
0.000 0.602 0.398
E46 Unspecified protein-energy malnutrition
0.000 0.618 0.382
E24.0 Pituitary-dependent Cushing's disease
0.000 0.626 0.374
E30.9 Disorder of puberty, unspecified
0.000 0.634 0.365
E30.8 Other disorders of puberty
0.000 0.634 0.365
E30.1 Precocious puberty
0.000 0.634 0.365
E30.0 Delayed puberty
0.000 0.634 0.365
E31.9 Polyglandular dysfunction, unspecified
0.000 0.634 0.365
E31.8 Other polyglandular dysfunction
0.000 0.634 0.365
E31.1 Polyglandular hyperfunction
0.000 0.634 0.365
E31.0 Autoimmune polyglandular failure
0.000 0.634 0.365
E32.9 Disease of thymus, unspecified
0.000 0.634 0.365
E32.8 Other diseases of thymus
0.000 0.634 0.365
E32.1 Abscess of thymus
0.000 0.634 0.365
E32.0 Persistent hyperplasia of thymus
0.000 0.634 0.365
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.634 0.365
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.634 0.365
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.634 0.365
E25.9 Adrenogenital disorder, unspecified
0.000 0.642 0.358
E25.8 Other adrenogenital disorders
0.000 0.642 0.358
E29.9 Testicular dysfunction, unspecified
0.000 0.651 0.349
E29.8 Other testicular dysfunction
0.000 0.651 0.349
E29.0 Testicular hyperfunction
0.000 0.651 0.349
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.652 0.347
E65 Localised adiposity
0.000 0.657 0.343
E50-E64 Other nutritional deficiencies
0.000 0.670 0.329
E67 Other hyperalimentation
0.000 0.672 0.328
E68 Sequelae of hyperalimentation
0.000 0.672 0.328
E29.1 Testicular hypofunction
0.000 0.674 0.326
E14 Unspecified diabetes mellitus
0.000 0.685 0.315
E44.1 Mild protein-energy malnutrition
0.000 0.686 0.313
E44.0 Moderate protein-energy malnutrition
0.000 0.686 0.313
E28.9 Ovarian dysfunction, unspecified
0.000 0.687 0.313
E28.8 Other ovarian dysfunction
0.000 0.687 0.313
E28.1 Androgen excess
0.000 0.687 0.313
E28.0 Oestrogen excess
0.000 0.687 0.313
E26.8 Other hyperaldosteronism
0.000 0.706 0.294
E26.1 Secondary hyperaldosteronism
0.000 0.706 0.294
E28.3 Primary ovarian failure
0.000 0.711 0.289
E04.2 Non-toxic multinodular goitre
0.000 0.724 0.276
E27.9 Disorder of adrenal gland, unspecified
0.001 0.727 0.273
E26.9 Hyperaldosteronism, unspecified
0.000 0.727 0.273
E14.3 With ophthalmic complications
0.000 0.728 0.272
E28.2 Polycystic ovarian syndrome
0.000 0.729 0.271
E23 Hypofunction and other disorders of pituitary gland
0.000 0.748 0.251
E70-E90 Metabolic disorders
0.000 0.756 0.244
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.764 0.236
E63 Other nutritional deficiencies
0.000 0.764 0.236
E56 Other vitamin deficiencies
0.000 0.764 0.236
E51 Thiamine deficiency
0.000 0.764 0.236
E50 Vitamin A deficiency
0.000 0.764 0.236
E60 Dietary zinc deficiency
0.000 0.764 0.236
E59 Dietary selenium deficiency
0.000 0.764 0.236
E58 Dietary calcium deficiency
0.000 0.764 0.236
E54 Ascorbic acid deficiency
0.000 0.764 0.236
E52 Niacin deficiency [pellagra]
0.000 0.764 0.236
E67.8 Other specified hyperalimentation
0.000 0.765 0.235
E67.3 Hypervitaminosis D
0.000 0.765 0.235
E67.2 Megavitamin-B6 syndrome
0.000 0.765 0.235
E67.1 Hypercarotenaemia
0.000 0.765 0.235
E67.0 Hypervitaminosis A
0.000 0.765 0.235
E26.0 Primary hyperaldosteronism
0.000 0.772 0.228
E14.7 With multiple complications
0.000 0.774 0.226
E14.6 With other specified complications
0.000 0.774 0.226
E14.2 Withrenal complications
0.000 0.774 0.226
E14.0 With coma
0.000 0.774 0.226
E14.8 With unspecified complications
0.000 0.775 0.225
L40-L45 Papulosquamous disorders
0.212 0.786 0.003
E83 Disorders of mineral metabolism
0.000 0.788 0.212
E85 Amyloidosis
0.000 0.796 0.204
E83.1 Disorders of iron metabolism
0.000 0.801 0.199
E14.4 With neurological complications
0.000 0.805 0.194
E74 Other disorders of carbohydrate metabolism
0.000 0.807 0.193
E14.1 With ketoacidosis
0.000 0.807 0.193
E23.6 Other disorders of pituitary gland
0.000 0.811 0.189
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.811 0.189
E55 Vitamin D deficiency
0.000 0.816 0.184
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.819 0.180
E23.1 Drug-induced hypopituitarism
0.000 0.819 0.180
E61 Deficiency of other nutrient elements
0.000 0.821 0.179
E77 Disorders of glycoprotein metabolism
0.000 0.825 0.175
E76 Disorders of glycosaminoglycan metabolism
0.000 0.825 0.175
E72 Other disorders of amino-acid metabolism
0.000 0.825 0.175
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.825 0.175
E70 Disorders of aromatic amino-acid metabolism
0.000 0.825 0.175
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.825 0.175
E85.4 Organ-limited amyloidosis
0.000 0.825 0.175
E84 Cystic fibrosis
0.000 0.826 0.174
E83.3 Disorders of phosphorus metabolism
0.000 0.827 0.173
E14.5 With peripheral circulatory complications
0.001 0.828 0.172
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.828 0.172
E83.4 Disorders of magnesium metabolism
0.000 0.830 0.170
E50.9 Vitamin A deficiency, unspecified
0.000 0.830 0.169
E50.8 Other manifestations of vitamin A deficiency
0.000 0.830 0.169
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.830 0.169
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.830 0.169
E50.5 Vitamin A deficiency with night blindness
0.000 0.830 0.169
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.830 0.169
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.830 0.169
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.830 0.169
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.830 0.169
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.830 0.169
E51.9 Thiamine deficiency, unspecified
0.000 0.830 0.169
E51.8 Other manifestations of thiamine deficiency
0.000 0.830 0.169
E51.2 Wernicke's encephalopathy
0.000 0.830 0.169
E51.1 Beriberi
0.000 0.830 0.169
E56.9 Vitamin deficiency, unspecified
0.000 0.830 0.169
E56.8 Deficiency of other vitamins
0.000 0.830 0.169
E56.1 Deficiency of vitamin K
0.000 0.830 0.169
E56.0 Deficiency of vitamin E
0.000 0.830 0.169
E63.9 Nutritional deficiency, unspecified
0.000 0.830 0.169
E63.8 Other specified nutritional deficiencies
0.000 0.830 0.169
E63.1 Imbalance of constituents of food intake
0.000 0.830 0.169
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.830 0.169
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.830 0.169
E64.8 Sequelae of other nutritional deficiencies
0.000 0.830 0.169
E64.3 Sequelae of rickets
0.000 0.830 0.169
E64.2 Sequelae of vitamin C deficiency
0.000 0.830 0.169
E64.1 Sequelae of vitamin A deficiency
0.000 0.830 0.169
E64.0 Sequelae of protein-energy malnutrition
0.000 0.830 0.169
E79 Disorders of purine and pyrimidine metabolism
0.000 0.831 0.169
E89.0 Postprocedural hypothyroidism
0.000 0.833 0.167
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.836 0.163
E86 Volume depletion
0.000 0.837 0.163
E73 Lactose intolerance
0.000 0.837 0.163
E53 Deficiency of other B group vitamins
0.000 0.840 0.160
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.001 0.842 0.157
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.844 0.156
L44 Other papulosquamous disorders
0.152 0.846 0.002
L41 Parapsoriasis
0.152 0.846 0.002
L45 Papulosquamous disorders in diseases classified elsewhere
0.152 0.846 0.002
E83.8 Other disorders of mineral metabolism
0.000 0.848 0.152
E83.2 Disorders of zinc metabolism
0.000 0.848 0.152
E83.0 Disorders of copper metabolism
0.000 0.848 0.152
E85.3 Secondary systemic amyloidosis
0.000 0.852 0.148
E85.8 Other amyloidosis
0.000 0.854 0.146
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.854 0.146
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.854 0.146
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.854 0.146
E85.9 Amyloidosis, unspecified
0.000 0.856 0.144
L42 Pityriasis rosea
0.142 0.856 0.002
R41 Other symptoms and signs involving cognitive functions and awareness
0.000 0.861 0.139
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.861 0.138
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.861 0.138
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.861 0.138
E74.2 Disorders of galactose metabolism
0.000 0.861 0.138
E74.1 Disorders of fructose metabolism
0.000 0.861 0.138
E74.0 Glycogen storage disease
0.000 0.861 0.138
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.000 0.863 0.137
E89.2 Postprocedural hypoparathyroidism
0.000 0.864 0.136
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.864 0.135
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.864 0.135
E89.5 Postprocedural testicular hypofunction
0.000 0.864 0.135
E89.1 Postprocedural hypoinsulinaemia
0.000 0.864 0.135
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.865 0.134
R41.0 Disorientation, unspecified
0.000 0.866 0.134
E23.2 Diabetes insipidus
0.000 0.866 0.134
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.867 0.133
E55.0 Rickets, active
0.000 0.868 0.132
R41.2 Retrograde amnesia
0.000 0.869 0.131
R44 Other symptoms and signs involving general sensations and perceptions
0.000 0.870 0.130
E61.9 Deficiency of nutrient element, unspecified
0.000 0.872 0.128
E61.8 Deficiency of other specified nutrient elements
0.000 0.872 0.128
E61.7 Deficiency of multiple nutrient elements
0.000 0.872 0.128
E61.6 Vanadium deficiency
0.000 0.872 0.128
E61.5 Molybdenum deficiency
0.000 0.872 0.128
E61.4 Chromium deficiency
0.000 0.872 0.128
E61.3 Manganese deficiency
0.000 0.872 0.128
E61.0 Copper deficiency
0.000 0.872 0.128
E23.7 Disorder of pituitary gland, unspecified
0.001 0.873 0.127
R42 Dizziness and giddiness
0.000 0.873 0.127
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.874 0.126
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.874 0.126
E70.3 Albinism
0.000 0.874 0.126
E70.2 Disorders of tyrosine metabolism
0.000 0.874 0.126
E70.1 Other hyperphenylalaninaemias
0.000 0.874 0.126
E70.0 Classical phenylketonuria
0.000 0.874 0.126
E71.3 Disorders of fatty-acid metabolism
0.000 0.874 0.126
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.874 0.126
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.874 0.126
E71.0 Maple-syrup-urine disease
0.000 0.874 0.126
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.874 0.126
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.874 0.126
E72.5 Disorders of glycine metabolism
0.000 0.874 0.126
E72.4 Disorders of ornithine metabolism
0.000 0.874 0.126
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.874 0.126
E72.2 Disorders of urea cycle metabolism
0.000 0.874 0.126
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.874 0.126
E72.0 Disorders of amino-acid transport
0.000 0.874 0.126
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.874 0.126
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.874 0.126
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.874 0.126
E76.2 Other mucopolysaccharidoses
0.000 0.874 0.126
E76.1 Mucopolysaccharidosis, type II
0.000 0.874 0.126
E76.0 Mucopolysaccharidosis, type I
0.000 0.874 0.126
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.874 0.126
E77.8 Other disorders of glycoprotein metabolism
0.000 0.874 0.126
E77.1 Defects in glycoprotein degradation
0.000 0.874 0.126
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.874 0.126
E84.8 Cystic fibrosis with other manifestations
0.000 0.875 0.125
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.875 0.125
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.875 0.125
E84.9 Cystic fibrosis, unspecified
0.000 0.876 0.124
E75.6 Lipid storage disorder, unspecified
0.000 0.876 0.123
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.876 0.123
E75.3 Sphingolipidosis, unspecified
0.000 0.876 0.123
E75.2 Other sphingolipidosis
0.000 0.876 0.123
E75.1 Other gangliosidosis
0.000 0.876 0.123
E75.0 GM2 gangliosidosis
0.000 0.876 0.123
J84.1 Other interstitial pulmonary diseases with fibrosis
0.000 0.877 0.123
R40 Somnolence, stupor and coma
0.000 0.877 0.123
E23.0 Hypopituitarism
0.000 0.878 0.122
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.878 0.121
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.878 0.121
E79.1 Lesch-Nyhan syndrome
0.000 0.878 0.121
E89.4 Postprocedural ovarian failure
0.000 0.879 0.121
E75.5 Other lipid storage disorders
0.000 0.880 0.120
E53.9 Vitamin B deficiency, unspecified
0.000 0.881 0.119
R44.1 Visual hallucinations
0.000 0.881 0.119
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.882 0.117
E80.5 Crigler-Najjar syndrome
0.000 0.882 0.117
E80.3 Defects of catalase and peroxydase
0.000 0.882 0.117
E80.2 Other porphyria
0.000 0.882 0.117
E80.1 Porphyria cutanea tarda
0.000 0.882 0.117
E80.0 Hereditary erythropoietic porphyria
0.000 0.882 0.117
E73.8 Other lactose intolerance
0.000 0.883 0.117
E73.1 Secondary lactase deficiency
0.000 0.883 0.117
E73.0 Congenital lactase deficiency
0.000 0.883 0.117
E80.6 Other disorders of bilirubin metabolism
0.000 0.883 0.117
E89.3 Postprocedural hypopituitarism
0.000 0.883 0.116
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.884 0.115
E53.1 Pyridoxine deficiency
0.000 0.885 0.115
E53.0 Riboflavin deficiency
0.000 0.885 0.115
R44.0 Auditory hallucinations
0.000 0.886 0.114
E21.4 Other specified disorders of parathyroid gland
0.001 0.887 0.113
E21.2 Other hyperparathyroidism
0.001 0.887 0.113
L41.9 Parapsoriasis, unspecified
0.109 0.889 0.002
L41.8 Other parapsoriasis
0.109 0.889 0.002
L41.5 Retiform parapsoriasis
0.109 0.889 0.002
L41.4 Large plaque parapsoriasis
0.109 0.889 0.002
L41.3 Small plaque parapsoriasis
0.109 0.889 0.002
L41.2 Lymphomatoid papulosis
0.109 0.889 0.002
L41.1 Pityriasis lichenoides chronica
0.109 0.889 0.002
L41.0 Pityriasis lichenoides et varioliformis acuta
0.109 0.889 0.002
L44.9 Papulosquamous disorder, unspecified
0.109 0.889 0.002
L44.8 Other specified papulosquamous disorders
0.109 0.889 0.002
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.109 0.889 0.002
L44.3 Lichen ruber moniliformis
0.109 0.889 0.002
L44.2 Lichen striatus
0.109 0.889 0.002
L44.1 Lichen nitidus
0.109 0.889 0.002
L44.0 Pityriasis rubra pilaris
0.109 0.889 0.002
E21.5 Disorder of parathyroid gland, unspecified
0.001 0.889 0.110
E61.2 Magnesium deficiency
0.000 0.890 0.110
R40.2 Coma, unspecified
0.000 0.891 0.109
E88 Other metabolic disorders
0.000 0.891 0.109
R43 Disturbances of smell and taste
0.000 0.892 0.108
R41.1 Anterograde amnesia
0.000 0.893 0.107
E80.4 Gilbert's syndrome
0.000 0.894 0.106
E73.9 Lactose intolerance, unspecified
0.000 0.895 0.105
R44.3 Hallucinations, unspecified
0.000 0.897 0.103
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.001 0.897 0.103
R40.0 Somnolence
0.000 0.898 0.102
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness
0.000 0.899 0.101
E61.1 Iron deficiency
0.000 0.901 0.099
R41.3 Other amnesia
0.000 0.904 0.096
R46 Symptoms and signs involving appearance and behaviour
0.000 0.905 0.094
R44.2 Other hallucinations
0.000 0.906 0.094
J84 Other interstitial pulmonary diseases
0.000 0.908 0.092
K50-K52 Noninfective enteritis and colitis
0.000 0.908 0.092
R45 Symptoms and signs involving emotional state
0.000 0.910 0.090
R43.0 Anosmia
0.000 0.914 0.086
R44.8 Other and unspecified symptoms and signs involving general sensations and perceptions
0.000 0.917 0.083
R40.1 Stupor
0.000 0.918 0.082
J84.9 Interstitial pulmonary disease, unspecified
0.000 0.920 0.080
E55.9 Vitamin D deficiency, unspecified
0.000 0.920 0.079
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.921 0.078
R43.8 Other and unspecified disturbances of smell and taste
0.000 0.921 0.078
E88.9 Metabolic disorder, unspecified
0.000 0.922 0.078
E88.3 Tumour lysis syndrome
0.000 0.922 0.078
R43.2 Parageusia
0.000 0.922 0.077
R43.1 Parosmia
0.000 0.922 0.077
L43 Lichen planus
0.074 0.923 0.003
E66 Obesity
0.000 0.924 0.076
E88.8 Other specified metabolic disorders
0.000 0.925 0.074
J84.8 Other specified interstitial pulmonary diseases
0.000 0.925 0.074
R45.1 Restlessness and agitation
0.000 0.926 0.074
R45.4 Irritability and anger
0.000 0.928 0.072
K90-K93 Other diseases of the digestive system
0.000 0.929 0.071
R46.8 Other symptoms and signs involving appearance and behaviour
0.000 0.929 0.071
R46.2 Strange and inexplicable behaviour
0.000 0.930 0.070
R45.0 Nervousness
0.000 0.930 0.070
R46.7 Verbosity and circumstantial detail obscuring reason for contact
0.000 0.932 0.068
R46.6 Undue concern and preoccupation with stressful events
0.000 0.932 0.068
R46.5 Suspiciousness and marked evasiveness
0.000 0.932 0.068
R46.3 Overactivity
0.000 0.932 0.068
R46.1 Bizarre personal appearance
0.000 0.932 0.068
R46.0 Very low level of personal hygiene
0.000 0.932 0.068
J84.0 Alveolar and parietoalveolar conditions
0.000 0.934 0.066
R45.7 State of emotional shock and stress, unspecified
0.000 0.935 0.065
R45.3 Demoralisation and apathy
0.000 0.935 0.065
R45.5 Hostility
0.000 0.937 0.063
M35.0 Sicca syndrome [Sjogren]
0.000 0.938 0.062
R45.2 Unhappiness
0.000 0.940 0.060
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.942 0.058
R46.4 Slowness and poor responsiveness
0.000 0.942 0.058
E21.3 Hyperparathyroidism, unspecified
0.000 0.942 0.057
E88.2 Lipomatosis, not elsewhere classified
0.000 0.943 0.056
R45.6 Physical violence
0.000 0.944 0.056
L43.3 Subacute (active) lichen planus
0.054 0.944 0.002
L43.2 Lichenoid drug reaction
0.054 0.944 0.002
L43.1 Bullous lichen planus
0.054 0.944 0.002
L43.0 Hypertrophic lichen planus
0.054 0.944 0.002
E66.1 Drug-induced obesity
0.000 0.945 0.054
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.949 0.051
E66.8 Other obesity
0.000 0.949 0.050
L43.8 Other lichen planus
0.042 0.955 0.002
L30.9 Dermatitis, unspecified
0.000 0.956 0.044
L30 Other dermatitis
0.000 0.958 0.042
E66.0 Obesity due to excess calories
0.000 0.959 0.040
L20-L30 Dermatitis and eczema
0.000 0.960 0.040
L29 Pruritus
0.000 0.961 0.039
L29.9 Pruritus, unspecified
0.000 0.961 0.039
L30.8 Other specified dermatitis
0.000 0.961 0.038
R45.8 Other symptoms and signs involving emotional state
0.000 0.962 0.038
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.963 0.037
K93.1 Megacolon in Chagas' disease
0.000 0.963 0.037
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.963 0.037
L27 Dermatitis due to substances taken internally
0.000 0.964 0.036
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.964 0.036
L20 Atopic dermatitis
0.000 0.966 0.034

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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