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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs9263625
log Bayes Factor = 30.1219
Chromosome 6   position 31,075,161  (GRCh37) Explore rs9263625 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.002 0.998
E10-E14 Diabetes mellitus
0.000 0.005 0.995
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.007 0.993
M45.X9 Ankylosing spondylitis (Site unspecified)
0.990 0.010 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.010 0.990
E16 Other disorders of pancreatic internal secretion
0.000 0.012 0.988
E00-E07 Disorders of thyroid gland
0.001 0.014 0.985
E16.2 Hypoglycaemia, unspecified
0.000 0.014 0.986
G35 Multiple sclerosis
0.000 0.017 0.983
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.017 0.983
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.019 0.981
E10.1 With ketoacidosis
0.000 0.022 0.978
E03.9 Hypothyroidism, unspecified
0.973 0.027 0.000
E10.9 Without complications
0.000 0.036 0.964
L40.9 Psoriasis, unspecified
0.000 0.043 0.957
L40 Psoriasis
0.000 0.047 0.953
L40.5 Arthropathic psoriasis
0.000 0.050 0.950
E10.2 With renal complications
0.000 0.057 0.943
E06 Thyroiditis
0.000 0.093 0.907
M45 Ankylosing spondylitis
0.879 0.121 0.000
L40.0 Psoriasis vulgaris
0.000 0.133 0.867
E65-E68 Obesity and other hyperalimentation
0.000 0.162 0.838
E06.9 Thyroiditis, unspecified
0.000 0.176 0.823
E03 Other hypothyroidism
0.632 0.185 0.183
E10.5 With peripheral circulatory complications
0.000 0.207 0.793
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.791 0.209 0.000
E05.8 Other thyrotoxicosis
0.000 0.220 0.780
E10.8 With unspecified complications
0.000 0.222 0.778
E16.1 Other hypoglycaemia
0.000 0.225 0.775
M45.X2 Ankylosing spondylitis (Cervical region)
0.756 0.244 0.000
E10.4 With neurological complications
0.000 0.248 0.752
E13 Other specified diabetes mellitus
0.000 0.255 0.745
E06.3 Autoimmune thyroiditis
0.000 0.265 0.735
M45.X6 Ankylosing spondylitis (Lumbar region)
0.734 0.266 0.000
E10.6 With other specified complications
0.000 0.269 0.731
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.279 0.721
E50-E64 Other nutritional deficiencies
0.000 0.281 0.719
E10.7 With multiple complications
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.287 0.713
E15 Nondiabetic hypoglycaemic coma
0.000 0.290 0.710
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.292 0.708
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.292 0.708
E16.4 Abnormal secretion of gastrin
0.000 0.292 0.708
E16.3 Increased secretion of glucagon
0.000 0.292 0.708
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.001 0.293 0.706
E00 Congenital iodine-deficiency syndrome
0.001 0.293 0.706
E02 Subclinical iodine-deficiency hypothyroidism
0.001 0.293 0.706
E05.5 Thyroid crisis or storm
0.000 0.295 0.704
E05.4 Thyrotoxicosis factitia
0.000 0.295 0.704
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.295 0.704
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.295 0.704
E10.0 With coma
0.000 0.296 0.704
E11 Non-insulin-dependent diabetes mellitus
0.000 0.298 0.702
L40.1 Generalised pustular psoriasis
0.000 0.313 0.687
L40.4 Guttate psoriasis
0.000 0.317 0.683
L40.3 Pustulosis palmaris et plantaris
0.000 0.317 0.683
L40.2 Acrodermatitis continua
0.000 0.317 0.683
E65 Localised adiposity
0.000 0.318 0.682
E66 Obesity
0.000 0.331 0.669
E06.5 Other chronic thyroiditis
0.000 0.349 0.650
E06.4 Drug-induced thyroiditis
0.000 0.349 0.650
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.349 0.650
E06.1 Subacute thyroiditis
0.000 0.349 0.650
E06.0 Acute thyroiditis
0.000 0.349 0.650
E55 Vitamin D deficiency
0.000 0.362 0.638
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.363 0.637
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.630 0.370 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.630 0.370 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.630 0.370 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.630 0.370 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.630 0.370 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.630 0.370 0.000
E66.8 Other obesity
0.000 0.384 0.616
E11.3 With ophthalmic complications
0.000 0.388 0.612
E40-E46 Malnutrition
0.000 0.393 0.607
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.501 0.394 0.105
E67 Other hyperalimentation
0.000 0.399 0.601
E68 Sequelae of hyperalimentation
0.000 0.399 0.601
E11.6 With other specified complications
0.000 0.407 0.593
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.410 0.590
L40.8 Other psoriasis
0.000 0.414 0.586
E03.5 Myxoedema coma
0.453 0.416 0.131
E03.4 Atrophy of thyroid (acquired)
0.453 0.416 0.131
E03.3 Postinfectious hypothyroidism
0.453 0.416 0.131
E03.1 Congenital hypothyroidism without goitre
0.453 0.416 0.131
E03.0 Congenital hypothyroidism with diffuse goitre
0.453 0.416 0.131
E03.8 Other specified hypothyroidism
0.475 0.421 0.104
E55.9 Vitamin D deficiency, unspecified
0.000 0.421 0.579
K90 Intestinal malabsorption
0.000 0.432 0.568
E13.9 Without complications
0.000 0.435 0.565
E11.4 With neurological complications
0.000 0.443 0.557
E11.8 With unspecified complications
0.000 0.458 0.541
E11.2 With renal complications
0.000 0.465 0.535
E13.8 With unspecified complications
0.000 0.466 0.534
E13.7 With multiple complications
0.000 0.466 0.534
E13.6 With other specified complications
0.000 0.466 0.534
E13.5 With peripheral circulatory complications
0.000 0.466 0.534
E13.4 With neurological complications
0.000 0.466 0.534
E13.3 With ophthalmic complications
0.000 0.466 0.534
E13.2 With renal complications
0.000 0.466 0.534
E13.1 With ketoacidosis
0.000 0.466 0.534
E13.0 With coma
0.000 0.466 0.534
E05.9 Thyrotoxicosis, unspecified
0.000 0.467 0.533
G37 Other demyelinating diseases of central nervous system
0.000 0.483 0.517
E66.0 Obesity due to excess calories
0.000 0.484 0.515
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.485 0.515
E63 Other nutritional deficiencies
0.000 0.485 0.515
E51 Thiamine deficiency
0.000 0.485 0.515
E50 Vitamin A deficiency
0.000 0.485 0.515
E60 Dietary zinc deficiency
0.000 0.485 0.515
E59 Dietary selenium deficiency
0.000 0.485 0.515
E58 Dietary calcium deficiency
0.000 0.485 0.515
E54 Ascorbic acid deficiency
0.000 0.485 0.515
E52 Niacin deficiency [pellagra]
0.000 0.485 0.515
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.485 0.515
E12.9 Without complications
0.000 0.489 0.511
E12.8 With unspecified complications
0.000 0.489 0.511
E12.7 With multiple complications
0.000 0.489 0.511
E12.6 With other specified complications
0.000 0.489 0.511
E12.5 With peripheral circulatory complications
0.000 0.489 0.511
E12.4 With neurological complications
0.000 0.489 0.511
E12.3 With ophthalmic complications
0.000 0.489 0.511
E12.2 With renal complications
0.000 0.489 0.511
E12.1 With ketoacidosis
0.000 0.489 0.511
E12.0 With coma
0.000 0.489 0.511
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.001 0.493 0.506
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.001 0.493 0.506
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.001 0.493 0.506
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.001 0.493 0.506
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.001 0.493 0.506
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.001 0.493 0.506
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.001 0.493 0.506
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.001 0.493 0.506
E11.7 With multiple complications
0.000 0.496 0.504
L40-L45 Papulosquamous disorders
0.000 0.519 0.481
E66.1 Drug-induced obesity
0.000 0.520 0.480
E07 Other disorders of thyroid
0.002 0.530 0.468
E61 Deficiency of other nutrient elements
0.000 0.537 0.462
E70-E90 Metabolic disorders
0.000 0.539 0.461
E55.0 Rickets, active
0.000 0.543 0.457
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.546 0.454
E56 Other vitamin deficiencies
0.000 0.547 0.452
E11.1 With ketoacidosis
0.000 0.549 0.451
E83.1 Disorders of iron metabolism
0.000 0.552 0.448
E83 Disorders of mineral metabolism
0.000 0.552 0.448
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.000 0.552 0.448
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.565 0.435
E45 Retarded development following protein-energy malnutrition
0.000 0.565 0.435
E43 Unspecified severe protein-energy malnutrition
0.000 0.565 0.435
E42 Marasmic kwashiorkor
0.000 0.565 0.435
E41 Nutritional marasmus
0.000 0.565 0.435
E40 Kwashiorkor
0.000 0.565 0.435
K90.9 Intestinal malabsorption, unspecified
0.000 0.567 0.433
E67.8 Other specified hyperalimentation
0.000 0.569 0.431
E67.3 Hypervitaminosis D
0.000 0.569 0.431
E67.2 Megavitamin-B6 syndrome
0.000 0.569 0.431
E67.1 Hypercarotenaemia
0.000 0.569 0.431
E67.0 Hypervitaminosis A
0.000 0.569 0.431
E11.5 With peripheral circulatory complications
0.000 0.571 0.429
E11.0 With coma
0.000 0.577 0.422
E53 Deficiency of other B group vitamins
0.000 0.579 0.421
G37.9 Demyelinating disease of central nervous system, unspecified
0.000 0.583 0.417
K90.8 Other intestinal malabsorption
0.000 0.590 0.409
G36 Other acute disseminated demyelination
0.000 0.592 0.408
K90.3 Pancreatic steatorrhoea
0.000 0.593 0.407
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.593 0.407
K90.1 Tropical sprue
0.000 0.593 0.407
E14 Unspecified diabetes mellitus
0.000 0.603 0.397
E85 Amyloidosis
0.000 0.612 0.388
L42 Pityriasis rosea
0.000 0.614 0.386
G37.5 Concentric sclerosis [Balo]
0.000 0.629 0.371
G37.4 Subacute necrotising myelitis
0.000 0.629 0.371
G37.2 Central pontine myelinolysis
0.000 0.629 0.371
G37.1 Central demyelination of corpus callosum
0.000 0.629 0.371
G37.0 Diffuse sclerosis
0.000 0.629 0.371
E50.9 Vitamin A deficiency, unspecified
0.000 0.630 0.369
E50.8 Other manifestations of vitamin A deficiency
0.000 0.630 0.369
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.630 0.369
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.630 0.369
E50.5 Vitamin A deficiency with night blindness
0.000 0.630 0.369
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.630 0.369
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.630 0.369
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.630 0.369
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.630 0.369
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.630 0.369
E51.9 Thiamine deficiency, unspecified
0.000 0.630 0.369
E51.8 Other manifestations of thiamine deficiency
0.000 0.630 0.369
E51.2 Wernicke's encephalopathy
0.000 0.630 0.369
E51.1 Beriberi
0.000 0.630 0.369
E63.9 Nutritional deficiency, unspecified
0.000 0.630 0.369
E63.8 Other specified nutritional deficiencies
0.000 0.630 0.369
E63.1 Imbalance of constituents of food intake
0.000 0.630 0.369
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.630 0.369
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.630 0.369
E64.8 Sequelae of other nutritional deficiencies
0.000 0.630 0.369
E64.3 Sequelae of rickets
0.000 0.630 0.369
E64.2 Sequelae of vitamin C deficiency
0.000 0.630 0.369
E64.1 Sequelae of vitamin A deficiency
0.000 0.630 0.369
E64.0 Sequelae of protein-energy malnutrition
0.000 0.630 0.369
E83.5 Disorders of calcium metabolism
0.000 0.634 0.366
G37.8 Other specified demyelinating diseases of central nervous system
0.000 0.642 0.358
L44 Other papulosquamous disorders
0.000 0.655 0.345
L41 Parapsoriasis
0.000 0.655 0.345
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.655 0.345
L43 Lichen planus
0.000 0.656 0.344
E07.8 Other specified disorders of thyroid
0.001 0.659 0.340
E07.1 Dyshormogenetic goitre
0.001 0.663 0.336
E07.0 Hypersecretion of calcitonin
0.001 0.663 0.336
E61.2 Magnesium deficiency
0.000 0.666 0.334
E61.9 Deficiency of nutrient element, unspecified
0.000 0.668 0.332
E61.8 Deficiency of other specified nutrient elements
0.000 0.668 0.332
E61.7 Deficiency of multiple nutrient elements
0.000 0.668 0.332
E61.6 Vanadium deficiency
0.000 0.668 0.332
E61.5 Molybdenum deficiency
0.000 0.668 0.332
E61.4 Chromium deficiency
0.000 0.668 0.332
E61.3 Manganese deficiency
0.000 0.668 0.332
E61.0 Copper deficiency
0.000 0.668 0.332
E85.4 Organ-limited amyloidosis
0.000 0.668 0.332
E53.9 Vitamin B deficiency, unspecified
0.000 0.669 0.330
E88 Other metabolic disorders
0.000 0.670 0.330
E46 Unspecified protein-energy malnutrition
0.000 0.670 0.330
E84 Cystic fibrosis
0.000 0.670 0.330
E79 Disorders of purine and pyrimidine metabolism
0.000 0.670 0.330
E77 Disorders of glycoprotein metabolism
0.000 0.670 0.330
E76 Disorders of glycosaminoglycan metabolism
0.000 0.670 0.330
E72 Other disorders of amino-acid metabolism
0.000 0.670 0.330
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.670 0.330
E70 Disorders of aromatic amino-acid metabolism
0.000 0.670 0.330
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.670 0.330
E56.9 Vitamin deficiency, unspecified
0.000 0.675 0.324
E56.8 Deficiency of other vitamins
0.000 0.675 0.324
E56.0 Deficiency of vitamin E
0.000 0.675 0.324
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.679 0.321
E83.8 Other disorders of mineral metabolism
0.000 0.679 0.321
E83.2 Disorders of zinc metabolism
0.000 0.679 0.321
E83.0 Disorders of copper metabolism
0.000 0.679 0.321
E74 Other disorders of carbohydrate metabolism
0.000 0.682 0.317
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.687 0.312
E44.1 Mild protein-energy malnutrition
0.000 0.688 0.312
E44.0 Moderate protein-energy malnutrition
0.000 0.688 0.312
E14.4 With neurological complications
0.000 0.691 0.309
E53.1 Pyridoxine deficiency
0.000 0.698 0.302
E53.0 Riboflavin deficiency
0.000 0.698 0.302
E73 Lactose intolerance
0.000 0.703 0.296
G36.9 Acute disseminated demyelination, unspecified
0.000 0.707 0.292
G36.8 Other specified acute disseminated demyelination
0.000 0.707 0.292
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.000 0.707 0.292
E14.1 With ketoacidosis
0.000 0.713 0.287
E86 Volume depletion
0.000 0.714 0.286
E14.8 With unspecified complications
0.000 0.715 0.285
E14.7 With multiple complications
0.000 0.715 0.285
E14.2 Withrenal complications
0.000 0.715 0.285
E14.0 With coma
0.000 0.715 0.285
E85.9 Amyloidosis, unspecified
0.000 0.715 0.285
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.718 0.282
L43.8 Other lichen planus
0.000 0.718 0.282
E85.8 Other amyloidosis
0.000 0.722 0.278
E85.3 Secondary systemic amyloidosis
0.000 0.722 0.278
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.722 0.278
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.722 0.278
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.722 0.278
G36.0 Neuromyelitis optica [Devic]
0.000 0.723 0.277
E61.1 Iron deficiency
0.000 0.724 0.276
E14.3 With ophthalmic complications
0.000 0.730 0.270
E14.6 With other specified complications
0.000 0.733 0.267
E56.1 Deficiency of vitamin K
0.001 0.738 0.261
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.744 0.256
E88.2 Lipomatosis, not elsewhere classified
0.000 0.746 0.254
E14.5 With peripheral circulatory complications
0.000 0.749 0.250
L41.9 Parapsoriasis, unspecified
0.000 0.752 0.248
L41.8 Other parapsoriasis
0.000 0.752 0.248
L41.5 Retiform parapsoriasis
0.000 0.752 0.248
L41.4 Large plaque parapsoriasis
0.000 0.752 0.248
L41.3 Small plaque parapsoriasis
0.000 0.752 0.248
L41.2 Lymphomatoid papulosis
0.000 0.752 0.248
L41.1 Pityriasis lichenoides chronica
0.000 0.752 0.248
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.752 0.248
L44.9 Papulosquamous disorder, unspecified
0.000 0.752 0.248
L44.8 Other specified papulosquamous disorders
0.000 0.752 0.248
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.752 0.248
L44.3 Lichen ruber moniliformis
0.000 0.752 0.248
L44.2 Lichen striatus
0.000 0.752 0.248
L44.1 Lichen nitidus
0.000 0.752 0.248
L44.0 Pityriasis rubra pilaris
0.000 0.752 0.248
L43.3 Subacute (active) lichen planus
0.000 0.753 0.247
L43.2 Lichenoid drug reaction
0.000 0.753 0.247
L43.1 Bullous lichen planus
0.000 0.753 0.247
L43.0 Hypertrophic lichen planus
0.000 0.753 0.247
E88.9 Metabolic disorder, unspecified
0.000 0.763 0.237
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.763 0.237
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.763 0.237
E70.3 Albinism
0.000 0.763 0.237
E70.2 Disorders of tyrosine metabolism
0.000 0.763 0.237
E70.1 Other hyperphenylalaninaemias
0.000 0.763 0.237
E70.0 Classical phenylketonuria
0.000 0.763 0.237
E71.3 Disorders of fatty-acid metabolism
0.000 0.763 0.237
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.763 0.237
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.763 0.237
E71.0 Maple-syrup-urine disease
0.000 0.763 0.237
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.763 0.237
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.763 0.237
E72.5 Disorders of glycine metabolism
0.000 0.763 0.237
E72.4 Disorders of ornithine metabolism
0.000 0.763 0.237
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.763 0.237
E72.2 Disorders of urea cycle metabolism
0.000 0.763 0.237
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.763 0.237
E72.0 Disorders of amino-acid transport
0.000 0.763 0.237
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.763 0.237
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.763 0.237
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.763 0.237
E76.2 Other mucopolysaccharidoses
0.000 0.763 0.237
E76.1 Mucopolysaccharidosis, type II
0.000 0.763 0.237
E76.0 Mucopolysaccharidosis, type I
0.000 0.763 0.237
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.763 0.237
E77.8 Other disorders of glycoprotein metabolism
0.000 0.763 0.237
E77.1 Defects in glycoprotein degradation
0.000 0.763 0.237
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.763 0.237
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.763 0.237
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.763 0.237
E79.1 Lesch-Nyhan syndrome
0.000 0.763 0.237
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.763 0.237
E84.9 Cystic fibrosis, unspecified
0.000 0.763 0.237
E84.8 Cystic fibrosis with other manifestations
0.000 0.763 0.237
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.763 0.237
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.763 0.237
E89.2 Postprocedural hypoparathyroidism
0.000 0.772 0.228
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.772 0.228
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.772 0.228
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.772 0.228
E74.2 Disorders of galactose metabolism
0.000 0.772 0.228
E74.1 Disorders of fructose metabolism
0.000 0.772 0.228
E74.0 Glycogen storage disease
0.000 0.772 0.228
E04 Other non-toxic goitre
0.000 0.774 0.225
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.775 0.225
E75.6 Lipid storage disorder, unspecified
0.000 0.776 0.224
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.776 0.224
E75.3 Sphingolipidosis, unspecified
0.000 0.776 0.224
E75.2 Other sphingolipidosis
0.000 0.776 0.224
E75.1 Other gangliosidosis
0.000 0.776 0.224
E75.0 GM2 gangliosidosis
0.000 0.776 0.224
E88.8 Other specified metabolic disorders
0.000 0.778 0.222
E88.3 Tumour lysis syndrome
0.000 0.778 0.221
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.785 0.215
E73.8 Other lactose intolerance
0.000 0.787 0.213
E73.1 Secondary lactase deficiency
0.000 0.787 0.213
E73.0 Congenital lactase deficiency
0.000 0.787 0.213
E75.5 Other lipid storage disorders
0.000 0.793 0.206
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.798 0.202
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.798 0.202
E89.5 Postprocedural testicular hypofunction
0.000 0.798 0.202
E89.1 Postprocedural hypoinsulinaemia
0.000 0.798 0.202
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.805 0.195
E89.0 Postprocedural hypothyroidism
0.000 0.807 0.193
E83.4 Disorders of magnesium metabolism
0.000 0.809 0.191
L43.9 Lichen planus, unspecified
0.000 0.810 0.190
E89.4 Postprocedural ovarian failure
0.000 0.814 0.186
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.819 0.181
E73.9 Lactose intolerance, unspecified
0.000 0.821 0.179
E20-E35 Disorders of other endocrine glands
0.001 0.823 0.176
E04.8 Other specified non-toxic goitre
0.000 0.838 0.162
E04.0 Non-toxic diffuse goitre
0.000 0.838 0.161
E83.3 Disorders of phosphorus metabolism
0.000 0.840 0.159
E89.3 Postprocedural hypopituitarism
0.000 0.846 0.153
E04.9 Non-toxic goitre, unspecified
0.000 0.857 0.143
E53.8 Deficiency of other specified B group vitamins
0.000 0.861 0.139
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.869 0.131
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.870 0.130
E80.5 Crigler-Najjar syndrome
0.000 0.870 0.130
E80.3 Defects of catalase and peroxydase
0.000 0.870 0.130
E80.1 Porphyria cutanea tarda
0.000 0.870 0.130
E80.0 Hereditary erythropoietic porphyria
0.000 0.870 0.130
E22 Hyperfunction of pituitary gland
0.000 0.871 0.128
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.873 0.126
E32 Diseases of thymus
0.000 0.873 0.126
E31 Polyglandular dysfunction
0.000 0.873 0.126
E30 Disorders of puberty, not elsewhere classified
0.000 0.873 0.126
E25 Adrenogenital disorders
0.000 0.873 0.126
E20 Hypoparathyroidism
0.000 0.875 0.124
E27 Other disorders of adrenal gland
0.000 0.880 0.120
E80.6 Other disorders of bilirubin metabolism
0.000 0.883 0.116
E34 Other endocrine disorders
0.000 0.885 0.114
E80.2 Other porphyria
0.000 0.885 0.114
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.888 0.112
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.889 0.111
E29 Testicular dysfunction
0.000 0.890 0.109
E22.1 Hyperprolactinaemia
0.000 0.891 0.109
E21.0 Primary hyperparathyroidism
0.000 0.891 0.109
E26 Hyperaldosteronism
0.001 0.891 0.108
E24 Cushing's syndrome
0.001 0.891 0.108
M06.9 Rheumatoid arthritis, unspecified
0.107 0.893 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.105 0.895 0.000
E27.1 Primary adrenocortical insufficiency
0.000 0.895 0.104
E23 Hypofunction and other disorders of pituitary gland
0.000 0.899 0.100
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.098 0.902 0.000
E87.5 Hyperkalaemia
0.000 0.903 0.097
M45-M49 Spondylopathies
0.096 0.904 0.000
M06 Other rheumatoid arthritis
0.096 0.904 0.000
E22.0 Acromegaly and pituitary gigantism
0.000 0.904 0.095
E21.4 Other specified disorders of parathyroid gland
0.000 0.906 0.094
E21.2 Other hyperparathyroidism
0.000 0.906 0.094
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.907 0.092
E22.8 Other hyperfunction of pituitary gland
0.000 0.907 0.092
E34.0 Carcinoid syndrome
0.000 0.908 0.092
M06.0 Seronegative rheumatoid arthritis
0.092 0.908 0.000
E25.9 Adrenogenital disorder, unspecified
0.001 0.909 0.091
E25.8 Other adrenogenital disorders
0.001 0.909 0.091
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.001 0.909 0.091
E30.9 Disorder of puberty, unspecified
0.001 0.909 0.091
E30.8 Other disorders of puberty
0.001 0.909 0.091
E30.1 Precocious puberty
0.001 0.909 0.091
E30.0 Delayed puberty
0.001 0.909 0.091
E31.9 Polyglandular dysfunction, unspecified
0.001 0.909 0.091
E31.8 Other polyglandular dysfunction
0.001 0.909 0.091
E31.1 Polyglandular hyperfunction
0.001 0.909 0.091
E31.0 Autoimmune polyglandular failure
0.001 0.909 0.091
E32.9 Disease of thymus, unspecified
0.001 0.909 0.091
E32.8 Other diseases of thymus
0.001 0.909 0.091
E32.1 Abscess of thymus
0.001 0.909 0.091
E32.0 Persistent hyperplasia of thymus
0.001 0.909 0.091
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.001 0.909 0.091
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.001 0.909 0.091
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.001 0.909 0.091
E20.8 Other hypoparathyroidism
0.000 0.910 0.089
E20.1 Pseudohypoparathyroidism
0.000 0.910 0.089
E20.0 Idiopathic hypoparathyroidism
0.000 0.910 0.089
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.089 0.911 0.000
E87.7 Fluid overload
0.000 0.912 0.088
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.088 0.912 0.000
E20.9 Hypoparathyroidism, unspecified
0.000 0.912 0.087
E07.9 Disorder of thyroid, unspecified
0.002 0.913 0.085
E27.8 Other specified disorders of adrenal gland
0.000 0.913 0.086
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.086 0.914 0.000
E27.5 Adrenomedullary hyperfunction
0.000 0.914 0.086
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.914 0.086
E27.0 Other adrenocortical overactivity
0.000 0.914 0.086
E87.2 Acidosis
0.000 0.914 0.086
E23.6 Other disorders of pituitary gland
0.000 0.916 0.084
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.917 0.083
M06.3 Rheumatoid nodule
0.083 0.917 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.083 0.917 0.000
E34.5 Androgen resistance syndrome
0.001 0.917 0.082
E34.4 Constitutional tall stature
0.001 0.917 0.082
E34.3 Short stature, not elsewhere classified
0.001 0.917 0.082
E34.2 Ectopic hormone secretion, not elsewhere classified
0.001 0.917 0.082
E34.1 Other hypersecretion of intestinal hormones
0.001 0.917 0.082
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.082 0.918 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.082 0.918 0.000
E87.4 Mixed disorder of acid-base balance
0.000 0.919 0.081
E27.9 Disorder of adrenal gland, unspecified
0.000 0.921 0.079
E29.9 Testicular dysfunction, unspecified
0.000 0.921 0.079
E29.8 Other testicular dysfunction
0.000 0.921 0.079
E29.0 Testicular hyperfunction
0.000 0.921 0.079
E14.9 Without complications
0.000 0.921 0.079
E23.7 Disorder of pituitary gland, unspecified
0.000 0.921 0.078
E24.8 Other Cushing's syndrome
0.001 0.922 0.078
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.001 0.922 0.078
E24.3 Ectopic ACTH syndrome
0.001 0.922 0.078
E24.1 Nelson's syndrome
0.001 0.922 0.078
E24.0 Pituitary-dependent Cushing's disease
0.001 0.922 0.078
E26.9 Hyperaldosteronism, unspecified
0.001 0.922 0.078
E26.8 Other hyperaldosteronism
0.001 0.922 0.078
E26.1 Secondary hyperaldosteronism
0.001 0.922 0.078
E34.9 Endocrine disorder, unspecified
0.000 0.923 0.077
M06.98 Rheumatoid arthritis, unspecified (Other)
0.077 0.923 0.000
E04.2 Non-toxic multinodular goitre
0.000 0.923 0.076
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.925 0.075
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.925 0.075
M06.34 Rheumatoid nodule (Hand)
0.075 0.925 0.000
E87.3 Alkalosis
0.000 0.927 0.073
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.073 0.927 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.927 0.072
E23.1 Drug-induced hypopituitarism
0.000 0.927 0.072
E24.2 Drug-induced Cushing's syndrome
0.001 0.929 0.071
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.071 0.929 0.000
M06.8 Other specified rheumatoid arthritis
0.069 0.931 0.000
M06.2 Rheumatoid bursitis
0.069 0.931 0.000
M06.1 Adult-onset Still's disease
0.069 0.931 0.000
E24.9 Cushing's syndrome, unspecified
0.000 0.931 0.069
M13.99 Arthritis, unspecified (Site unspecified)
0.000 0.931 0.069
M46 Other inflammatory spondylopathies
0.069 0.931 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.067 0.933 0.000
M06.08 Seronegative rheumatoid arthritis (Other)
0.066 0.934 0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.066 0.934 0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.066 0.934 0.000
M06.04 Seronegative rheumatoid arthritis (Hand)
0.066 0.934 0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.066 0.934 0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.066 0.934 0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.066 0.934 0.000
E78.2 Mixed hyperlipidaemia
0.000 0.934 0.065
M06.4 Inflammatory polyarthropathy
0.065 0.935 0.000
E27.2 Addisonian crisis
0.000 0.937 0.063
M49 Spondylopathies in diseases classified elsewhere
0.063 0.937 0.000
E29.1 Testicular hypofunction
0.000 0.938 0.062
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.061 0.939 0.000
E87.6 Hypokalaemia
0.000 0.939 0.061
E80.4 Gilbert's syndrome
0.000 0.939 0.060
E34.8 Other specified endocrine disorders
0.001 0.940 0.060
E26.0 Primary hyperaldosteronism
0.001 0.940 0.059

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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