TreeWAS – Variant ID: rs9267444

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	1.000	0.000	0.000
E05.9 Thyrotoxicosis, unspecified	1.000	0.000	0.000
E10.9 Without complications	1.000	0.000	0.000
E10.3 With ophthalmic complications	1.000	0.000	0.000
K90.0 Coeliac disease	1.000	0.000	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	1.000	0.000	0.000
E05 Thyrotoxicosis [hyperthyroidism]	1.000	0.000	0.000
E10 Insulin-dependent diabetes mellitus	1.000	0.000	0.000
E10-E14 Diabetes mellitus	1.000	0.000	0.000
E00-E07 Disorders of thyroid gland	1.000	0.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000	0.000
E05.0 Thyrotoxicosis with diffuse goitre	1.000	0.000	0.000
E03 Other hypothyroidism	1.000	0.000	0.000
M45 Ankylosing spondylitis	1.000	0.000	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.999	0.001	0.000
E16 Other disorders of pancreatic internal secretion	0.999	0.001	0.000
L40.9 Psoriasis, unspecified	0.000	0.003	0.997
E16.2 Hypoglycaemia, unspecified	0.997	0.003	0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.995	0.005	0.000
M35.0 Sicca syndrome [Sjogren]	0.994	0.006	0.000
E14 Unspecified diabetes mellitus	0.989	0.011	0.000
E10.2 With renal complications	0.980	0.020	0.000
E10.1 With ketoacidosis	0.978	0.022	0.000
E14.3 With ophthalmic complications	0.974	0.026	0.000
M45.X2 Ankylosing spondylitis (Cervical region)	0.956	0.044	0.000
K90 Intestinal malabsorption	0.956	0.044	0.000
E10.4 With neurological complications	0.951	0.049	0.000
M35 Other systemic involvement of connective tissue	0.921	0.079	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.915	0.085	0.000
E13 Other specified diabetes mellitus	0.914	0.086	0.000
L40 Psoriasis	0.019	0.091	0.890
L40-L45 Papulosquamous disorders	0.868	0.106	0.026
L43.9 Lichen planus, unspecified	0.886	0.114	0.000
L43 Lichen planus	0.876	0.115	0.009
M45.X6 Ankylosing spondylitis (Lumbar region)	0.881	0.119	0.000
Chapter VII Diseases of the eye and adnexa	0.877	0.123	0.000
H30-H36 Disorders of choroid and retina	0.877	0.123	0.000
# Top node	0.876	0.124	0.000
H36 Retinal disorders in diseases classified elsewhere	0.875	0.125	0.000
H36.0 Diabetic retinopathy	0.875	0.125	0.000
L40.0 Psoriasis vulgaris	0.003	0.128	0.869
Chapter XII Diseases of the skin and subcutaneous tissue	0.869	0.131	0.000
K90-K93 Other diseases of the digestive system	0.866	0.134	0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.862	0.138	0.000
H34 Retinal vascular occlusions	0.862	0.138	0.000
K70-K77 Diseases of liver	0.859	0.141	0.000
M45-M49 Spondylopathies	0.858	0.142	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.855	0.145	0.000
Chapter XI Diseases of the digestive system	0.854	0.146	0.000
M20-M25 Other joint disorders	0.846	0.154	0.000
E14.8 With unspecified complications	0.846	0.154	0.000
E13.9 Without complications	0.841	0.159	0.000
H34.8 Other retinal vascular occlusions	0.835	0.165	0.000
Chapter I Certain infectious and parasitic diseases	0.832	0.168	0.000
H05 Disorders of orbit	0.831	0.169	0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere	0.818	0.182	0.000
K75 Other inflammatory liver diseases	0.818	0.182	0.000
A00-A09 Intestinal infectious diseases	0.817	0.183	0.000
A08.4 Viral intestinal infection, unspecified	0.816	0.184	0.000
A08 Viral and other specified intestinal infections	0.816	0.184	0.000
K75.4 Autoimmune hepatitis	0.814	0.186	0.000
E10.0 With coma	0.811	0.189	0.000
K74 Fibrosis and cirrhosis of liver	0.811	0.189	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.810	0.190	0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.807	0.193	0.000
E10.7 With multiple complications	0.804	0.196	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.803	0.197	0.000
M34 Systemic sclerosis	0.801	0.199	0.000
C85.1 B-cell lymphoma, unspecified	0.801	0.199	0.000
A50-A64 Infections with a predominantly sexual mode of transmission	0.798	0.202	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.798	0.202	0.000
E16.1 Other hypoglycaemia	0.797	0.203	0.000
H06.2 Dysthyroid exophthalmos	0.787	0.213	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.785	0.215	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.776	0.224	0.000
K72 Hepatic failure, not elsewhere classified	0.776	0.224	0.000
E07 Other disorders of thyroid	0.774	0.226	0.000
A63 Other predominantly sexually transmitted diseases, not elsewhere classified	0.774	0.226	0.000
L40.8 Other psoriasis	0.009	0.228	0.764
K70 Alcoholic liver disease	0.767	0.233	0.000
H05.0 Acute inflammation of orbit	0.767	0.233	0.000
H04 Disorders of lachrymal system	0.760	0.240	0.000
L10-L14 Bullous disorders	0.759	0.241	0.000
A63.0 Anogenital (venereal) warts	0.758	0.242	0.000
L50-L54 Urticaria and erythema	0.755	0.245	0.000
K74.3 Primary biliary cirrhosis	0.751	0.249	0.000
E14.1 With ketoacidosis	0.747	0.253	0.000
E14.2 Withrenal complications	0.746	0.253	0.000
H05.2 Exophthalmic conditions	0.747	0.253	0.000
K90.9 Intestinal malabsorption, unspecified	0.746	0.254	0.000
E06 Thyroiditis	0.742	0.258	0.000
K72.0 Acute and subacute hepatic failure	0.741	0.259	0.000
E40-E46 Malnutrition	0.741	0.259	0.000
H34.2 Other retinal artery occlusions	0.738	0.262	0.000
K73 Chronic hepatitis, not elsewhere classified	0.733	0.267	0.000
E14.5 With peripheral circulatory complications	0.730	0.270	0.000
K90.8 Other intestinal malabsorption	0.728	0.272	0.000
E10.8 With unspecified complications	0.726	0.274	0.000
E14.4 With neurological complications	0.725	0.275	0.000
K70.4 Alcoholic hepatic failure	0.724	0.276	0.000
M35.3 Polymyalgia rheumatica	0.723	0.277	0.000
E05.5 Thyroid crisis or storm	0.717	0.283	0.000
E05.4 Thyrotoxicosis factitia	0.717	0.283	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.717	0.283	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.717	0.283	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.717	0.283	0.000
E00 Congenital iodine-deficiency syndrome	0.717	0.283	0.000
E12 Malnutrition-related diabetes mellitus	0.717	0.283	0.000
E03.5 Myxoedema coma	0.717	0.283	0.000
E03.4 Atrophy of thyroid (acquired)	0.717	0.283	0.000
E03.3 Postinfectious hypothyroidism	0.717	0.283	0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.717	0.283	0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.717	0.283	0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.717	0.283	0.000
M45.X4 Ankylosing spondylitis (Thoracic region)	0.717	0.283	0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.717	0.283	0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.717	0.283	0.000
E15 Nondiabetic hypoglycaemic coma	0.716	0.284	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.716	0.284	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.716	0.284	0.000
E16.4 Abnormal secretion of gastrin	0.716	0.284	0.000
E16.3 Increased secretion of glucagon	0.716	0.284	0.000
K74.6 Other and unspecified cirrhosis of liver	0.715	0.285	0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.712	0.288	0.000
M35.7 Hypermobility syndrome	0.710	0.290	0.000
H46 Optic neuritis	0.709	0.291	0.000
E14.7 With multiple complications	0.709	0.291	0.000
E14.0 With coma	0.709	0.291	0.000
E03.8 Other specified hypothyroidism	0.708	0.292	0.000
M35.1 Other overlap syndromes	0.706	0.294	0.000
B35-B49 Mycoses	0.703	0.297	0.000
H55-H59 Other disorders of eye and adnexa	0.701	0.299	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.696	0.303	0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.695	0.305	0.000
E13.3 With ophthalmic complications	0.694	0.306	0.000
K77 Liver disorders in diseases classified elsewhere	0.693	0.307	0.000
M34.1 CR(E)ST syndrome	0.693	0.307	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.692	0.308	0.000
E05.8 Other thyrotoxicosis	0.691	0.309	0.000
H50 Other strabismus	0.690	0.310	0.000
E10.5 With peripheral circulatory complications	0.688	0.311	0.000
D60-D64 Aplastic and other anaemias	0.688	0.312	0.000
H34.1 Central retinal artery occlusion	0.686	0.314	0.000
K90.3 Pancreatic steatorrhoea	0.685	0.315	0.000
K90.2 Blind loop syndrome, not elsewhere classified	0.685	0.315	0.000
K90.1 Tropical sprue	0.685	0.315	0.000
M00-M03 Infectious arthropathies	0.684	0.316	0.000
A08.3 Other viral enteritis	0.681	0.319	0.000
M91-M94 Chondropathies	0.677	0.323	0.000
M34.9 Systemic sclerosis, unspecified	0.677	0.323	0.000
H03 Disorders of eyelid in diseases classified elsewhere	0.676	0.324	0.000
L43.0 Hypertrophic lichen planus	0.666	0.328	0.006
H04.1 Other disorders of lachrymal gland	0.671	0.329	0.000
H05.8 Other disorders of orbit	0.669	0.331	0.000
D61 Other aplastic anaemias	0.669	0.331	0.000
M32 Systemic lupus erythematosus	0.667	0.333	0.000
B35 Dermatophytosis	0.666	0.334	0.000
M35.2 Behcet's disease	0.665	0.334	0.000
L13 Other bullous disorders	0.665	0.335	0.000
L52 Erythema nodosum	0.664	0.336	0.000
Chapter XXII Codes for special purposes	0.664	0.336	0.000
M34.8 Other forms of systemic sclerosis	0.663	0.337	0.000
K74.5 Biliary cirrhosis, unspecified	0.661	0.339	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.660	0.339	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.660	0.339	0.000
M35.5 Multifocal fibrosclerosis	0.660	0.339	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.660	0.339	0.000
K71 Toxic liver disease	0.659	0.341	0.000
E10.6 With other specified complications	0.659	0.341	0.000
E13.8 With unspecified complications	0.655	0.345	0.000
E13.7 With multiple complications	0.655	0.345	0.000
E13.6 With other specified complications	0.655	0.345	0.000
E13.5 With peripheral circulatory complications	0.655	0.345	0.000
E13.4 With neurological complications	0.655	0.345	0.000
E13.2 With renal complications	0.655	0.345	0.000
E13.1 With ketoacidosis	0.655	0.345	0.000
E13.0 With coma	0.655	0.345	0.000
D80-D89 Certain disorders involving the immune mechanism	0.655	0.345	0.000
L40.1 Generalised pustular psoriasis	0.013	0.346	0.642
D61.9 Aplastic anaemia, unspecified	0.654	0.346	0.000
E07.8 Other specified disorders of thyroid	0.653	0.347	0.000
L44 Other papulosquamous disorders	0.634	0.347	0.018
L40.2 Acrodermatitis continua	0.014	0.348	0.638
E03.1 Congenital hypothyroidism without goitre	0.651	0.349	0.000
E14.6 With other specified complications	0.648	0.352	0.000
K70.9 Alcoholic liver disease, unspecified	0.648	0.352	0.000
H50.5 Heterophoria	0.648	0.352	0.000
H30 Chorioretinal inflammation	0.643	0.357	0.000
A65-A69 Other spirochaetal diseases	0.643	0.357	0.000
H04.8 Other disorders of lachrymal system	0.642	0.358	0.000
L41 Parapsoriasis	0.622	0.359	0.019
L45 Papulosquamous disorders in diseases classified elsewhere	0.622	0.359	0.019
Chapter XVI Certain conditions originating in the perinatal period	0.639	0.361	0.000
H04.4 Chronic inflammation of lachrymal passages	0.637	0.362	0.000
E06.3 Autoimmune thyroiditis	0.637	0.363	0.000
K73.9 Chronic hepatitis, unspecified	0.636	0.364	0.000
A05 Other bacterial foodborne intoxications	0.636	0.364	0.000
L43.3 Subacute (active) lichen planus	0.628	0.366	0.006
L43.2 Lichenoid drug reaction	0.628	0.366	0.006
L43.1 Bullous lichen planus	0.628	0.366	0.006
H04.9 Disorder of lachrymal system, unspecified	0.630	0.370	0.000
L80-L99 Other disorders of the skin and subcutaneous tissue	0.629	0.371	0.000
H32 Chorioretinal disorders in diseases classified elsewhere	0.629	0.371	0.000
B15-B19 Viral hepatitis	0.628	0.372	0.000
H36.8 Other retinal disorders in diseases classified elsewhere	0.627	0.373	0.000
E14.9 Without complications	0.625	0.375	0.000
K72.1 Chronic hepatic failure	0.622	0.378	0.000
K93 Disorders of other digestive organs in diseases classified elsewhere	0.621	0.379	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.619	0.381	0.000
H34.0 Transient retinal artery occlusion	0.618	0.382	0.000
L40.4 Guttate psoriasis	0.014	0.385	0.601
A06 Amoebiasis	0.614	0.386	0.000
L56 Other acute skin changes due to ultraviolet radiation	0.612	0.388	0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified	0.610	0.390	0.000
E20-E35 Disorders of other endocrine glands	0.610	0.390	0.000
D69 Purpura and other haemorrhagic conditions	0.610	0.390	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.609	0.390	0.000
L92 Granulomatous disorders of skin and subcutaneous tissue	0.609	0.391	0.000
A30-A49 Other bacterial diseases	0.609	0.391	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.606	0.393	0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.605	0.395	0.000
A52 Late syphilis	0.604	0.396	0.000
B85-B89 Pediculosis, acariasis and other infestations	0.603	0.397	0.000
B35.1 Tinea unguium	0.603	0.397	0.000
M34.0 Progressive systemic sclerosis	0.600	0.400	0.000
H50.0 Convergent concomitant strabismus	0.600	0.400	0.000
H25-H28 Disorders of lens	0.600	0.400	0.000
L13.0 Dermatitis herpetiformis	0.598	0.402	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.598	0.402	0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.596	0.403	0.000
A75-A79 Rickettsioses	0.596	0.403	0.000
A70-A74 Other diseases caused by chlamydiae	0.596	0.403	0.000
H05.5 Retained (old) foreign body following penetrating wound of orbit	0.596	0.404	0.000
H05.3 Deformity of orbit	0.596	0.404	0.000
H05.1 Chronic inflammatory disorders of orbit	0.596	0.404	0.000
H55 Nystagmus and other irregular eye movements	0.594	0.406	0.000
A20-A28 Certain zoonotic bacterial diseases	0.592	0.408	0.000
L94 Other localised connective tissue disorders	0.592	0.408	0.000
L43.8 Other lichen planus	0.584	0.410	0.006
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.589	0.411	0.000
H34.9 Retinal vascular occlusion, unspecified	0.588	0.412	0.000
B20-B24 Human immunodeficiency virus [HIV] disease	0.588	0.412	0.000
H50.9 Strabismus, unspecified	0.588	0.412	0.000
L12 Pemphigoid	0.587	0.413	0.000
H06.3 Other disorders of orbit in diseases classified elsewhere	0.586	0.413	0.000
H06.1 Parasitic infestation of orbit in diseases classified elsewhere	0.586	0.413	0.000
H06.0 Disorders of lachrymal system in diseases classified elsewhere	0.586	0.413	0.000
K75.2 Nonspecific reactive hepatitis	0.586	0.414	0.000
K75.1 Phlebitis of portal vein	0.586	0.414	0.000
A03 Shigellosis	0.586	0.414	0.000
A01 Typhoid and paratyphoid fevers	0.586	0.414	0.000
A00 Cholera	0.586	0.414	0.000
A08.5 Other specified intestinal infections	0.585	0.415	0.000
A08.2 Adenoviral enteritis	0.585	0.415	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.585	0.415	0.000
A08.0 Rotaviral enteritis	0.582	0.418	0.000
A80-A89 Viral infections of the central nervous system	0.582	0.418	0.000
K74.4 Secondary biliary cirrhosis	0.582	0.418	0.000
K74.2 Hepatic fibrosis with hepatic sclerosis	0.582	0.418	0.000
K74.1 Hepatic sclerosis	0.582	0.418	0.000
A02 Other Salmonella infections	0.582	0.418	0.000
D55-D59 Haemolytic anaemias	0.581	0.419	0.000
L42 Pityriasis rosea	0.559	0.422	0.019
C83.3 Large cell (diffuse)	0.577	0.423	0.000
C85.0 Lymphosarcoma	0.576	0.424	0.000
B65-B83 Helminthiases	0.576	0.424	0.000
M02 Reactive arthropathies	0.575	0.425	0.000
M34.2 Systemic sclerosis induced by drugs and chemicals	0.574	0.426	0.000
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.574	0.426	0.000
A59 Trichomoniasis	0.572	0.427	0.000
A56 Other sexually transmitted chlamydial diseases	0.572	0.427	0.000
A54 Gonococcal infection	0.572	0.427	0.000
A53 Other and unspecified syphilis	0.572	0.427	0.000
A51 Early syphilis	0.572	0.427	0.000
A50 Congenital syphilis	0.572	0.427	0.000
A64 Unspecified sexually transmitted disease	0.572	0.427	0.000
A58 Granuloma inguinale	0.572	0.427	0.000
A57 Chancroid	0.572	0.427	0.000
A55 Chlamydial lymphogranuloma (venereum)	0.572	0.427	0.000
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified	0.572	0.428	0.000
H05.9 Disorder of orbit, unspecified	0.571	0.429	0.000
L92.3 Foreign body granuloma of skin and subcutaneous tissue	0.564	0.436	0.000
N00-N08 Glomerular diseases	0.564	0.436	0.000
M30 Polyarteritis nodosa and related conditions	0.563	0.436	0.000
C85.7 Other specified types of non-Hodgkin's lymphoma	0.563	0.437	0.000
N05 Unspecified nephritic syndrome	0.563	0.437	0.000
N04 Nephrotic syndrome	0.563	0.437	0.000
K70.0 Alcoholic fatty liver	0.561	0.439	0.000
H43-H45 Disorders of vitreous body and globe	0.561	0.439	0.000
L10 Pemphigus	0.561	0.439	0.000
B90-B94 Sequelae of infectious and parasitic diseases	0.559	0.441	0.000
B35.3 Tinea pedis	0.558	0.442	0.000
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere	0.556	0.443	0.000
N05.2 Diffuse membranous glomerulonephritis	0.556	0.444	0.000
M49 Spondylopathies in diseases classified elsewhere	0.556	0.444	0.000
M35.8 Other specified systemic involvement of connective tissue	0.555	0.444	0.000
E07.1 Dyshormogenetic goitre	0.555	0.445	0.000
E07.0 Hypersecretion of calcitonin	0.555	0.445	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.555	0.445	0.000
E46 Unspecified protein-energy malnutrition	0.555	0.445	0.000
B99-B99 Other infectious diseases	0.555	0.445	0.000
D80 Immunodeficiency with predominantly antibody defects	0.555	0.445	0.000
H31 Other disorders of choroid	0.554	0.446	0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.551	0.448	0.000
L51 Erythema multiforme	0.551	0.449	0.000
L53 Other erythematous conditions	0.550	0.450	0.000
M33 Dermatopolymyositis	0.550	0.450	0.000
L95 Vasculitis limited to skin, not elsewhere classified	0.549	0.451	0.000
N04.9 Unspecified	0.549	0.451	0.000
A60 Anogenital herpesviral [herpes simplex] infections	0.548	0.452	0.000
L40.3 Pustulosis palmaris et plantaris	0.015	0.453	0.531
M92 Other juvenile osteochondrosis	0.546	0.454	0.000
L50 Urticaria	0.545	0.454	0.000
H04.0 Dacryoadenitis	0.545	0.455	0.000
H04.3 Acute and unspecified inflammation of lachrymal passages	0.544	0.456	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.544	0.456	0.000
L14 Bullous disorders in diseases classified elsewhere	0.544	0.456	0.000
M60-M63 Disorders of muscles	0.543	0.457	0.000
H03.1 Involvement of eyelid in other infectious diseases classified elsewhere	0.542	0.458	0.000
L54 Erythema in diseases classified elsewhere	0.541	0.458	0.000
A46 Erysipelas	0.542	0.458	0.000
L93 Lupus erythematosus	0.539	0.461	0.000
H50.6 Mechanical strabismus	0.538	0.462	0.000
H47 Other disorders of optic [2nd] nerve and visual pathways	0.538	0.462	0.000
H50.2 Vertical strabismus	0.537	0.463	0.000
D69.4 Other primary thrombocytopenia	0.536	0.464	0.000
L80 Vitiligo	0.536	0.464	0.000
D83 Common variable immunodeficiency	0.534	0.466	0.000
D68 Other coagulation defects	0.533	0.467	0.000
C81 Hodgkin's disease	0.533	0.467	0.000
A07 Other protozoal intestinal diseases	0.532	0.468	0.000
E06.4 Drug-induced thyroiditis	0.532	0.468	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.532	0.468	0.000
E06.1 Subacute thyroiditis	0.532	0.468	0.000
E06.0 Acute thyroiditis	0.532	0.468	0.000
H59.8 Other postprocedural disorders of eye and adnexa	0.531	0.469	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.531	0.469	0.000
E45 Retarded development following protein-energy malnutrition	0.531	0.469	0.000
E43 Unspecified severe protein-energy malnutrition	0.531	0.469	0.000
E42 Marasmic kwashiorkor	0.531	0.469	0.000
E41 Nutritional marasmus	0.531	0.469	0.000
E40 Kwashiorkor	0.531	0.469	0.000
K75.3 Granulomatous hepatitis, not elsewhere classified	0.531	0.469	0.000
H05.4 Enophthalmos	0.530	0.470	0.000
H26 Other cataract	0.530	0.470	0.000
A15-A19 Tuberculosis	0.528	0.472	0.000
K75.8 Other specified inflammatory liver diseases	0.528	0.472	0.000
B35.6 Tinea cruris	0.527	0.472	0.000
B36 Other superficial mycoses	0.527	0.473	0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.526	0.474	0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.526	0.474	0.000
E06.5 Other chronic thyroiditis	0.525	0.475	0.000
A63.8 Other specified predominantly sexually transmitted diseases	0.525	0.475	0.000
M93 Other osteochondropathies	0.525	0.475	0.000
K71.1 Toxic liver disease with hepatic necrosis	0.524	0.476	0.000
L58 Radiodermatitis	0.523	0.477	0.000
N03 Chronic nephritic syndrome	0.521	0.479	0.000
L94.0 Localised scleroderma [morphea]	0.521	0.479	0.000
E24 Cushing's syndrome	0.521	0.479	0.000
D63 Anaemia in chronic diseases classified elsewhere	0.520	0.480	0.000
E22 Hyperfunction of pituitary gland	0.520	0.480	0.000
M32.1 Systemic lupus erythematosus with organ or system involvement	0.520	0.480	0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere	0.519	0.481	0.000
M22 Disorders of patella	0.518	0.482	0.000
D68.8 Other specified coagulation defects	0.518	0.482	0.000
B18 Chronic viral hepatitis	0.518	0.482	0.000
K70.2 Alcoholic fibrosis and sclerosis of liver	0.517	0.483	0.000
D69.2 Other nonthrombocytopenic purpura	0.517	0.483	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.514	0.486	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.514	0.486	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.514	0.486	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.514	0.486	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.514	0.486	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.514	0.486	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.514	0.486	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.514	0.486	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.514	0.486	0.000
E12.9 Without complications	0.514	0.486	0.000
E12.8 With unspecified complications	0.514	0.486	0.000
E12.7 With multiple complications	0.514	0.486	0.000
E12.6 With other specified complications	0.514	0.486	0.000
E12.5 With peripheral circulatory complications	0.514	0.486	0.000
E12.4 With neurological complications	0.514	0.486	0.000
E12.3 With ophthalmic complications	0.514	0.486	0.000
E12.2 With renal complications	0.514	0.486	0.000
E12.1 With ketoacidosis	0.514	0.486	0.000
E12.0 With coma	0.514	0.486	0.000
L11 Other acantholytic disorders	0.513	0.487	0.000
U88 Agent resistant to multiple antibiotics	0.512	0.488	0.000
D61.1 Drug-induced aplastic anaemia	0.509	0.491	0.000
L94.9 Localised connective tissue disorder, unspecified	0.509	0.491	0.000
C83.7 Burkitt's tumour	0.508	0.492	0.000
A69 Other spirochaetal infections	0.507	0.492	0.000
E28 Ovarian dysfunction	0.507	0.493	0.000
A05.9 Bacterial foodborne intoxication, unspecified	0.506	0.494	0.000
B48 Other mycoses, not elsewhere classified	0.504	0.496	0.000
B47 Mycetoma	0.504	0.496	0.000
B46 Zygomycosis	0.504	0.496	0.000
B45 Cryptococcosis	0.504	0.496	0.000
B43 Chromomycosis and phaeomycotic abscess	0.504	0.496	0.000
B42 Sporotrichosis	0.504	0.496	0.000
B41 Paracoccidioidomycosis	0.504	0.496	0.000
B40 Blastomycosis	0.504	0.496	0.000
B39 Histoplasmosis	0.504	0.496	0.000
B38 Coccidioidomycosis	0.504	0.496	0.000
H01 Other inflammation of eyelid	0.504	0.496	0.000
D69.6 Thrombocytopenia, unspecified	0.503	0.497	0.000
M32.8 Other forms of systemic lupus erythematosus	0.503	0.497	0.000
L56.9 Acute skin change due to ultraviolet radiation, unspecified	0.503	0.497	0.000
B25-B34 Other viral diseases	0.501	0.499	0.000
M15-M19 Arthrosis	0.501	0.499	0.000
H51 Other disorders of binocular movement	0.501	0.499	0.000
L95.8 Other vasculitis limited to skin	0.500	0.500	0.000
E23 Hypofunction and other disorders of pituitary gland	0.499	0.501	0.000
L55 Sunburn	0.499	0.501	0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin	0.498	0.502	0.000
B16 Acute hepatitis B	0.498	0.502	0.000
N04.1 Focal and segmental glomerular lesions	0.498	0.502	0.000
D69.8 Other specified haemorrhagic conditions	0.497	0.503	0.000
K77.8 Liver disorders in other diseases classified elsewhere	0.497	0.503	0.000
D67 Hereditary factor IX deficiency	0.496	0.503	0.000
L84 Corns and callosities	0.496	0.504	0.000
M02.3 Reiter's disease	0.495	0.505	0.000
H50.3 Intermittent heterotropia	0.495	0.505	0.000
L56.8 Other specified acute skin changes due to ultraviolet radiation	0.495	0.505	0.000
B82 Unspecified intestinal parasitism	0.494	0.506	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.494	0.506	0.000
H04.5 Stenosis and insufficiency of lachrymal passages	0.493	0.507	0.000
C83.1 Small cleaved cell (diffuse)	0.492	0.508	0.000
D84 Other immunodeficiencies	0.492	0.508	0.000
M03 Postinfective and reactive arthropathies in diseases classified elsewhere	0.490	0.510	0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere	0.490	0.510	0.000
H04.6 Other changes in lachrymal passages	0.489	0.511	0.000
N05.1 Focal and segmental glomerular lesions	0.488	0.512	0.000
H50.4 Other and unspecified heterotropia	0.488	0.512	0.000
L20-L30 Dermatitis and eczema	0.487	0.513	0.000
K71.0 Toxic liver disease with cholestasis	0.486	0.514	0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.485	0.515	0.000
H03.8 Involvement of eyelid in other diseases classified elsewhere	0.484	0.515	0.000
H03.0 Parasitic infestation of eyelid in diseases classified elsewhere	0.484	0.515	0.000
N08 Glomerular disorders in diseases classified elsewhere	0.484	0.516	0.000
E07.9 Disorder of thyroid, unspecified	0.483	0.517	0.000
L12.0 Bullous pemphigoid	0.482	0.518	0.000
D61.8 Other specified aplastic anaemias	0.480	0.520	0.000
D61.3 Idiopathic aplastic anaemia	0.480	0.520	0.000
D61.2 Aplastic anaemia due to other external agents	0.480	0.520	0.000
L44.0 Pityriasis rubra pilaris	0.467	0.521	0.012
M32.9 Systemic lupus erythematosus, unspecified	0.478	0.522	0.000
M32.0 Drug-induced systemic lupus erythematosus	0.478	0.522	0.000
M18 Arthrosis of first carpometacarpal joint	0.478	0.522	0.000
B35.9 Dermatophytosis, unspecified	0.477	0.522	0.000
B35.8 Other dermatophytoses	0.477	0.522	0.000
B35.5 Tinea imbricata	0.477	0.522	0.000
B35.4 Tinea corporis	0.477	0.522	0.000
B35.2 Tinea manuum	0.477	0.522	0.000
B35.0 Tinea barbae and tinea capitis	0.477	0.522	0.000
L13.9 Bullous disorder, unspecified	0.477	0.523	0.000
L13.8 Other specified bullous disorders	0.477	0.523	0.000
L13.1 Subcorneal pustular dermatitis	0.477	0.523	0.000
N04.2 Diffuse membranous glomerulonephritis	0.477	0.523	0.000
H30.9 Chorioretinal inflammation, unspecified	0.476	0.524	0.000
L59 Other disorders of skin and subcutaneous tissue related to radiation	0.475	0.524	0.000
H59.9 Postprocedural disorder of eye and adnexa, unspecified	0.475	0.525	0.000
D61.0 Constitutional aplastic anaemia	0.474	0.525	0.000
E50-E64 Other nutritional deficiencies	0.474	0.526	0.000
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified	0.473	0.526	0.000
K71.9 Toxic liver disease, unspecified	0.473	0.527	0.000
K71.8 Toxic liver disease with other disorders of liver	0.473	0.527	0.000
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.473	0.527	0.000
K71.5 Toxic liver disease with chronic active hepatitis	0.473	0.527	0.000
K71.4 Toxic liver disease with chronic lobular hepatitis	0.473	0.527	0.000
K71.3 Toxic liver disease with chronic persistent hepatitis	0.473	0.527	0.000
K71.2 Toxic liver disease with acute hepatitis	0.473	0.527	0.000
M30.8 Other conditions related to polyarteritis nodosa	0.472	0.528	0.000
L94.8 Other specified localised connective tissue disorders	0.471	0.529	0.000
D63.8 Anaemia in other chronic diseases classified elsewhere	0.471	0.529	0.000
A08.1 Acute gastro-enteropathy due to Norwalk agent	0.471	0.529	0.000
L56.4 Polymorphous light eruption	0.471	0.529	0.000
L51.9 Erythema multiforme, unspecified	0.470	0.530	0.000
D81 Combined immunodeficiencies	0.469	0.530	0.000
A06.4 Amoebic liver abscess	0.469	0.531	0.000
P10-P15 Birth trauma	0.469	0.531	0.000
L44.9 Papulosquamous disorder, unspecified	0.455	0.532	0.013
L44.8 Other specified papulosquamous disorders	0.455	0.532	0.013
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]	0.455	0.532	0.013
L44.3 Lichen ruber moniliformis	0.455	0.532	0.013
L44.2 Lichen striatus	0.455	0.532	0.013
L44.1 Lichen nitidus	0.455	0.532	0.013
H26.4 After-cataract	0.467	0.533	0.000
H43 Disorders of vitreous body	0.467	0.533	0.000
L53.0 Toxic erythema	0.467	0.533	0.000
M00 Pyogenic arthritis	0.465	0.535	0.000
M94 Other disorders of cartilage	0.465	0.535	0.000
M91 Juvenile osteochondrosis of hip and pelvis	0.464	0.536	0.000
A52.1 Symptomatic neurosyphilis	0.464	0.536	0.000
E31 Polyglandular dysfunction	0.464	0.536	0.000
E23.6 Other disorders of pituitary gland	0.463	0.537	0.000
K75.0 Abscess of liver	0.463	0.537	0.000
A49 Bacterial infection of unspecified site	0.463	0.537	0.000
L50.1 Idiopathic urticaria	0.463	0.537	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations