TreeWAS – Variant ID: rs9267947

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.000	1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.000	1.000
K90.0 Coeliac disease	1.000	0.000	0.000
M06.9 Rheumatoid arthritis, unspecified	0.000	0.000	1.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.000	1.000
M06 Other rheumatoid arthritis	0.000	0.000	1.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.000	0.000	1.000
E05.9 Thyrotoxicosis, unspecified	1.000	0.000	0.000
E05 Thyrotoxicosis [hyperthyroidism]	1.000	0.000	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	1.000	0.000	0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma	1.000	0.000	0.000
M05 Seropositive rheumatoid arthritis	0.000	0.001	0.999
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.999	0.001	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.999	0.001	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.998	0.002	0.000
M05-M14 Inflammatory polyarthropathies	0.000	0.002	0.998
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.003	0.997
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.997	0.003	0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.997	0.003	0.000
C83.3 Large cell (diffuse)	0.997	0.003	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.000	0.004	0.996
E00-E07 Disorders of thyroid gland	0.993	0.007	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.993	0.007	0.000
E10-E14 Diabetes mellitus	0.992	0.008	0.000
E10 Insulin-dependent diabetes mellitus	0.992	0.008	0.000
M06.3 Rheumatoid nodule	0.000	0.009	0.991
E20-E35 Disorders of other endocrine glands	0.978	0.022	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.023	0.977
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.969	0.031	0.000
E21.3 Hyperparathyroidism, unspecified	0.964	0.036	0.000
E10.9 Without complications	0.961	0.039	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.000	0.043	0.957
C85.1 B-cell lymphoma, unspecified	0.955	0.045	0.000
M06.34 Rheumatoid nodule (Hand)	0.000	0.045	0.955
E13 Other specified diabetes mellitus	0.953	0.047	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.000	0.061	0.939
C82.1 Mixed small cleaved and large cell, follicular	0.934	0.066	0.000
E13.9 Without complications	0.926	0.074	0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.920	0.080	0.000
E10.3 With ophthalmic complications	0.920	0.080	0.000
M06.4 Inflammatory polyarthropathy	0.000	0.086	0.914
M12 Other specific arthropathies	0.000	0.097	0.903
E40-E46 Malnutrition	0.884	0.116	0.000
C82.0 Small cleaved cell, follicular	0.879	0.121	0.000
M06.0 Seronegative rheumatoid arthritis	0.000	0.123	0.877
M06.37 Rheumatoid nodule (Ankle and foot)	0.000	0.124	0.876
E10.4 With neurological complications	0.875	0.125	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.000	0.142	0.858
C83.1 Small cleaved cell (diffuse)	0.856	0.144	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.855	0.145	0.000
N04.9 Unspecified	0.851	0.149	0.000
N04 Nephrotic syndrome	0.851	0.149	0.000
N00-N08 Glomerular diseases	0.847	0.153	0.000
E28 Ovarian dysfunction	0.845	0.155	0.000
C83.7 Burkitt's tumour	0.839	0.161	0.000
E10.1 With ketoacidosis	0.838	0.162	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.000	0.165	0.835
M06.32 Rheumatoid nodule (Upper arm)	0.000	0.170	0.830
E24 Cushing's syndrome	0.830	0.170	0.000
C95 Leukaemia of unspecified cell type	0.826	0.174	0.000
C84 Peripheral and cutaneous T-cell lymphomas	0.823	0.177	0.000
N08 Glomerular disorders in diseases classified elsewhere	0.823	0.177	0.000
N05 Unspecified nephritic syndrome	0.821	0.179	0.000
M12.3 Palindromic rheumatism	0.000	0.189	0.811
N08.3 Glomerular disorders in diabetes mellitus	0.809	0.191	0.000
E10.2 With renal complications	0.807	0.193	0.000
E46 Unspecified protein-energy malnutrition	0.806	0.194	0.000
E10.5 With peripheral circulatory complications	0.804	0.196	0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.000	0.200	0.800
M05.8 Other seropositive rheumatoid arthritis	0.000	0.203	0.797
C82.2 Large cell, follicular	0.793	0.207	0.000
N03 Chronic nephritic syndrome	0.790	0.210	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.213	0.787
E10.8 With unspecified complications	0.786	0.213	0.000
E26 Hyperaldosteronism	0.780	0.220	0.000
E28.2 Polycystic ovarian syndrome	0.777	0.223	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.227	0.773
E21.2 Other hyperparathyroidism	0.773	0.227	0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.768	0.232	0.000
E34 Other endocrine disorders	0.768	0.232	0.000
N05.2 Diffuse membranous glomerulonephritis	0.767	0.233	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.234	0.766
E10.7 With multiple complications	0.765	0.235	0.000
M06.30 Rheumatoid nodule (Multiple sites)	0.000	0.238	0.762
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.000	0.238	0.762
C94 Other leukaemias of specified cell type	0.758	0.241	0.000
C81 Hodgkin's disease	0.757	0.243	0.000
E16 Other disorders of pancreatic internal secretion	0.757	0.243	0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.000	0.244	0.756
E21.5 Disorder of parathyroid gland, unspecified	0.747	0.253	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.000	0.268	0.732
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.275	0.725
M12.2 Villonodular synovitis (pigmented)	0.000	0.276	0.724
E07 Other disorders of thyroid	0.722	0.278	0.000
N05.1 Focal and segmental glomerular lesions	0.721	0.279	0.000
M05.2 Rheumatoid vasculitis	0.000	0.281	0.719
M06.2 Rheumatoid bursitis	0.000	0.283	0.717
M06.1 Adult-onset Still's disease	0.000	0.283	0.717
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.000	0.283	0.717
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.283	0.717
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.000	0.283	0.717
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.000	0.283	0.717
E05.5 Thyroid crisis or storm	0.717	0.283	0.000
E05.4 Thyrotoxicosis factitia	0.717	0.283	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.717	0.283	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.717	0.283	0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.717	0.283	0.000
C82.6 Cutaneous follicle centre lymphoma	0.717	0.283	0.000
C82.5 Diffuse follicle centre lymphoma	0.717	0.283	0.000
C86 Other specified types of T/NK-cell lymphoma	0.716	0.284	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.000	0.284	0.716
M05.1 Rheumatoid lung disease	0.000	0.284	0.716
M05.0 Felty's syndrome	0.000	0.284	0.716
C85.0 Lymphosarcoma	0.716	0.284	0.000
E20 Hypoparathyroidism	0.716	0.284	0.000
C82.3 Follicular lymphoma grade IIIa	0.715	0.285	0.000
C83.6 Undifferentiated (diffuse)	0.715	0.285	0.000
C83.5 Lymphoblastic (diffuse)	0.715	0.285	0.000
C83.4 Immunoblastic (diffuse)	0.715	0.285	0.000
C83.2 Mixed small and large cell (diffuse)	0.715	0.285	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.000	0.285	0.715
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.712	0.288	0.000
E00 Congenital iodine-deficiency syndrome	0.712	0.288	0.000
E12 Malnutrition-related diabetes mellitus	0.712	0.288	0.000
M06.39 Rheumatoid nodule (Site unspecified)	0.000	0.290	0.710
M06.38 Rheumatoid nodule (Other)	0.000	0.290	0.710
M06.36 Rheumatoid nodule (Lower leg)	0.000	0.290	0.710
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.000	0.290	0.710
M06.33 Rheumatoid nodule (Forearm)	0.000	0.290	0.710
M06.31 Rheumatoid nodule (Shoulder region)	0.000	0.290	0.710
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.000	0.291	0.709
M12.39 Palindromic rheumatism (Site unspecified)	0.000	0.294	0.706
E35 Disorders of endocrine glands in diseases classified elsewhere	0.701	0.299	0.000
E32 Diseases of thymus	0.701	0.299	0.000
E30 Disorders of puberty, not elsewhere classified	0.701	0.299	0.000
E31 Polyglandular dysfunction	0.700	0.300	0.000
M20.1 Hallux valgus (acquired)	0.000	0.301	0.699
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.000	0.302	0.698
E21.4 Other specified disorders of parathyroid gland	0.695	0.305	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.691	0.309	0.000
E14 Unspecified diabetes mellitus	0.690	0.310	0.000
N03.9 Unspecified	0.689	0.311	0.000
M06.46 Inflammatory polyarthropathy (Lower leg)	0.000	0.311	0.688
E03 Other hypothyroidism	0.688	0.312	0.000
E13.8 With unspecified complications	0.683	0.316	0.000
E13.7 With multiple complications	0.683	0.316	0.000
E13.6 With other specified complications	0.683	0.316	0.000
E13.5 With peripheral circulatory complications	0.683	0.316	0.000
E13.4 With neurological complications	0.683	0.316	0.000
E13.2 With renal complications	0.683	0.316	0.000
E13.1 With ketoacidosis	0.683	0.316	0.000
E13.0 With coma	0.683	0.316	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.682	0.318	0.000
E13.3 With ophthalmic complications	0.681	0.319	0.000
E24.2 Drug-induced Cushing's syndrome	0.680	0.320	0.000
E24.0 Pituitary-dependent Cushing's disease	0.680	0.320	0.000
E16.2 Hypoglycaemia, unspecified	0.680	0.320	0.000
N04.1 Focal and segmental glomerular lesions	0.678	0.322	0.000
M20 Acquired deformities of fingers and toes	0.000	0.323	0.677
N04.2 Diffuse membranous glomerulonephritis	0.677	0.323	0.000
E34.8 Other specified endocrine disorders	0.675	0.325	0.000
H00.1 Chalazion	0.000	0.333	0.667
N03.8 Other	0.666	0.334	0.000
M12.30 Palindromic rheumatism (Multiple sites)	0.000	0.335	0.665
M20.4 Other hammer toe(s) (acquired)	0.000	0.338	0.662
M06.04 Seronegative rheumatoid arthritis (Hand)	0.000	0.341	0.659
M08 Juvenile arthritis	0.000	0.341	0.658
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.658	0.342	0.000
M06.48 Inflammatory polyarthropathy (Other)	0.000	0.344	0.656
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.000	0.344	0.656
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.000	0.344	0.656
M06.44 Inflammatory polyarthropathy (Hand)	0.000	0.344	0.656
M06.43 Inflammatory polyarthropathy (Forearm)	0.000	0.344	0.656
M06.42 Inflammatory polyarthropathy (Upper arm)	0.000	0.344	0.656
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.000	0.344	0.656
C95.9 Leukaemia, unspecified	0.655	0.345	0.000
M12.5 Traumatic arthropathy	0.000	0.347	0.653
E26.0 Primary hyperaldosteronism	0.652	0.348	0.000
C84.5 Other and unspecified T-cell lymphomas	0.652	0.348	0.000
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)	0.000	0.348	0.652
C91 Lymphoid leukaemia	0.651	0.349	0.000
M12.4 Intermittent hydrarthrosis	0.000	0.352	0.648
M12.1 Kaschin-Beck disease	0.000	0.352	0.648
M12.0 Chronic postrheumatic arthropathy [Jaccoud]	0.000	0.352	0.648
E25 Adrenogenital disorders	0.643	0.357	0.000
C90 Multiple myeloma and malignant plasma cell neoplasms	0.642	0.358	0.000
M06.8 Other specified rheumatoid arthritis	0.000	0.360	0.640
M14 Arthropathies in other diseases classified elsewhere	0.000	0.362	0.638
C95.1 Chronic leukaemia of unspecified cell type	0.637	0.363	0.000
C84.8 Cutaneous T-cell lymphoma, unspecified	0.635	0.365	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.634	0.366	0.000
E45 Retarded development following protein-energy malnutrition	0.634	0.366	0.000
E43 Unspecified severe protein-energy malnutrition	0.634	0.366	0.000
E42 Marasmic kwashiorkor	0.634	0.366	0.000
E41 Nutritional marasmus	0.634	0.366	0.000
E40 Kwashiorkor	0.634	0.366	0.000
N04.0 Minor glomerular abnormality	0.633	0.367	0.000
C81.1 Nodular sclerosis	0.633	0.367	0.000
M12.8 Other specific arthropathies, not elsewhere classified	0.000	0.367	0.633
C88 Malignant immunoproliferative diseases	0.633	0.367	0.000
N05.3 Diffuse mesangial proliferative glomerulonephritis	0.633	0.367	0.000
K90 Intestinal malabsorption	0.632	0.368	0.000
M20.6 Acquired deformity of toe(s), unspecified	0.000	0.368	0.632
N05.5 Diffuse mesangiocapillary glomerulonephritis	0.631	0.369	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.000	0.371	0.629
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.000	0.371	0.629
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.000	0.371	0.629
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.000	0.371	0.629
N05.9 Unspecified	0.627	0.373	0.000
C82.4 Follicular lymphoma grade IIIb	0.626	0.373	0.000
K51.9 Ulcerative colitis, unspecified	0.000	0.380	0.620
E10.6 With other specified complications	0.619	0.381	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.615	0.385	0.000
C95.0 Acute leukaemia of unspecified cell type	0.614	0.386	0.000
E15 Nondiabetic hypoglycaemic coma	0.613	0.387	0.000
N08.1 Glomerular disorders in neoplastic diseases	0.613	0.387	0.000
E22 Hyperfunction of pituitary gland	0.612	0.388	0.000
C84.0 Mycosis fungoides	0.612	0.388	0.000
N08.4 Glomerular disorders in other endocrine, nutritional and metabolic diseases	0.612	0.388	0.000
N04.8 Other	0.610	0.390	0.000
N04.7 Diffuse crescentic glomerulonephritis	0.610	0.390	0.000
N04.6 Dense deposit disease	0.610	0.390	0.000
N04.5 Diffuse mesangiocapillary glomerulonephritis	0.610	0.390	0.000
N04.4 Diffuse endocapillary proliferative glomerulonephritis	0.610	0.390	0.000
N04.3 Diffuse mesangial proliferative glomerulonephritis	0.610	0.390	0.000
N05.8 Other	0.610	0.390	0.000
C91.9 Lymphoid leukaemia, unspecified	0.610	0.390	0.000
N03.1 Focal and segmental glomerular lesions	0.609	0.391	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.000	0.392	0.608
N07 Hereditary nephropathy, not elsewhere classified	0.608	0.392	0.000
N06 Isolated proteinuria with specified morphological lesion	0.608	0.392	0.000
N01 Rapidly progressive nephritic syndrome	0.608	0.392	0.000
N00 Acute nephritic syndrome	0.607	0.393	0.000
E28.9 Ovarian dysfunction, unspecified	0.606	0.394	0.000
E28.8 Other ovarian dysfunction	0.606	0.394	0.000
E28.1 Androgen excess	0.606	0.394	0.000
E28.0 Oestrogen excess	0.606	0.394	0.000
E07.8 Other specified disorders of thyroid	0.604	0.396	0.000
M35.3 Polymyalgia rheumatica	0.000	0.400	0.600
E24.8 Other Cushing's syndrome	0.595	0.405	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.595	0.405	0.000
E24.3 Ectopic ACTH syndrome	0.595	0.405	0.000
E24.1 Nelson's syndrome	0.595	0.405	0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.595	0.405	0.000
E05.8 Other thyrotoxicosis	0.595	0.405	0.000
C95.7 Other leukaemia of unspecified cell type	0.592	0.408	0.000
C95.2 Subacute leukaemia of unspecified cell type	0.592	0.408	0.000
C84.9 Mature T/NK-cell lymphoma, unspecified	0.590	0.410	0.000
C84.7 Anaplastic large cell lymphoma, ALK-negative	0.590	0.410	0.000
C84.6 Anaplastic large cell lymphoma, ALK-positive	0.590	0.410	0.000
C84.3 Lymphoepithelioid lymphoma	0.590	0.410	0.000
C84.2 T-zone lymphoma	0.590	0.410	0.000
C84.1 Sezary's diease	0.590	0.410	0.000
N08.8 Glomerular disorders in other diseases classified elsewhere	0.590	0.410	0.000
N08.2 Glomerular disorders in blood diseases and disorders involving the immune mechanism	0.590	0.410	0.000
N08.0 Glomerular disorders in infectious and parasitic diseases classified elsewhere	0.590	0.410	0.000
E10.0 With coma	0.589	0.411	0.000
N05.6 Dense deposit disease	0.588	0.411	0.000
N05.4 Diffuse endocapillary proliferative glomerulonephritis	0.588	0.411	0.000
N05.0 Minor glomerular abnormality	0.588	0.411	0.000
N03.5 Diffuse mesangiocapillary glomerulonephritis	0.588	0.412	0.000
C84.4 Peripheral T-cell lymphoma	0.587	0.413	0.000
C94.4 Acute panmyelosis	0.585	0.414	0.000
M12.26 Villonodular synovitis (pigmented) (Lower leg)	0.000	0.417	0.583
C81.0 Lymphocytic predominance	0.582	0.418	0.000
E29 Testicular dysfunction	0.582	0.418	0.000
M12.38 Palindromic rheumatism (Other)	0.000	0.419	0.581
M12.37 Palindromic rheumatism (Ankle and foot)	0.000	0.419	0.581
M12.36 Palindromic rheumatism (Lower leg)	0.000	0.419	0.581
M12.35 Palindromic rheumatism (Pelvic region and thigh)	0.000	0.419	0.581
M12.34 Palindromic rheumatism (Hand)	0.000	0.419	0.581
M12.33 Palindromic rheumatism (Forearm)	0.000	0.419	0.581
M12.32 Palindromic rheumatism (Upper arm)	0.000	0.419	0.581
M12.31 Palindromic rheumatism (Shoulder region)	0.000	0.419	0.581
E14.8 With unspecified complications	0.581	0.419	0.000
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)	0.000	0.429	0.571
M05.88 Other seropositive rheumatoid arthritis (Other)	0.000	0.429	0.571
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)	0.000	0.429	0.571
M05.86 Other seropositive rheumatoid arthritis (Lower leg)	0.000	0.429	0.571
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)	0.000	0.429	0.571
M05.84 Other seropositive rheumatoid arthritis (Hand)	0.000	0.429	0.571
M05.83 Other seropositive rheumatoid arthritis (Forearm)	0.000	0.429	0.571
M05.82 Other seropositive rheumatoid arthritis (Upper arm)	0.000	0.429	0.571
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)	0.000	0.429	0.571
Q61 Cystic kidney disease	0.570	0.430	0.000
E24.9 Cushing's syndrome, unspecified	0.570	0.430	0.000
N03.7 Diffuse crescentic glomerulonephritis	0.567	0.433	0.000
N03.6 Dense deposit disease	0.567	0.433	0.000
N03.4 Diffuse endocapillary proliferative glomerulonephritis	0.567	0.433	0.000
N03.3 Diffuse mesangial proliferative glomerulonephritis	0.567	0.433	0.000
N03.2 Diffuse membranous glomerulonephritis	0.567	0.433	0.000
N03.0 Minor glomerular abnormality	0.567	0.433	0.000
E14.4 With neurological complications	0.565	0.435	0.000
M35 Other systemic involvement of connective tissue	0.000	0.435	0.565
C93 Monocytic leukaemia	0.564	0.435	0.001
Q61.3 Polycystic kidney, unspecified	0.564	0.436	0.000
E23 Hypofunction and other disorders of pituitary gland	0.563	0.437	0.000
E16.1 Other hypoglycaemia	0.562	0.438	0.000
E26.8 Other hyperaldosteronism	0.559	0.440	0.000
E26.1 Secondary hyperaldosteronism	0.559	0.440	0.000
C90.3 Solitary plasmacytoma	0.554	0.446	0.000
M20-M25 Other joint disorders	0.000	0.448	0.552
E34.5 Androgen resistance syndrome	0.551	0.449	0.000
E34.4 Constitutional tall stature	0.551	0.449	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.551	0.449	0.000
E34.1 Other hypersecretion of intestinal hormones	0.551	0.449	0.000
E14.5 With peripheral circulatory complications	0.550	0.450	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.549	0.451	0.000
Q60-Q64 Congenital malformations of the urinary system	0.548	0.452	0.000
C92 Myeloid leukaemia	0.548	0.452	0.000
Q61.0 Congenital single renal cyst	0.545	0.455	0.000
C94.7 Other specified leukaemias	0.544	0.456	0.000
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified	0.544	0.456	0.000
C94.5 Acute myelofibrosis	0.544	0.456	0.000
C94.3 Mast cell leukaemia	0.544	0.456	0.000
C94.2 Acute megakaryoblastic leukaemia	0.544	0.456	0.000
C94.1 Chronic erythraemia	0.544	0.456	0.000
C94.0 Acute erythraemia and erythroleukaemia	0.544	0.456	0.000
H00 Hordeolum and chalazion	0.000	0.456	0.544
C81.4 Lymphocyte-rich classical Hodgkin lymphoma	0.543	0.457	0.000
C81.3 Lymphocytic depletion	0.543	0.457	0.000
M20.3 Other deformity of hallux (acquired)	0.000	0.457	0.543
E16.9 Disorder of pancreatic internal secretion, unspecified	0.542	0.457	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.542	0.457	0.000
E16.4 Abnormal secretion of gastrin	0.542	0.457	0.000
E16.3 Increased secretion of glucagon	0.542	0.457	0.000
C81.7 Other Hodgkin's disease	0.542	0.458	0.000
C81.2 Mixed cellularity	0.541	0.459	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.540	0.460	0.000
Q61.2 Polycystic kidney, adult type	0.539	0.461	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.538	0.462	0.000
E26.9 Hyperaldosteronism, unspecified	0.537	0.463	0.000
M12.24 Villonodular synovitis (pigmented) (Hand)	0.000	0.463	0.536
E14.1 With ketoacidosis	0.532	0.468	0.000
M31 Other necrotising vasculopathies	0.000	0.470	0.530
E20.9 Hypoparathyroidism, unspecified	0.528	0.472	0.000
E34.3 Short stature, not elsewhere classified	0.528	0.472	0.000
E34.9 Endocrine disorder, unspecified	0.526	0.474	0.000
K90.9 Intestinal malabsorption, unspecified	0.525	0.475	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.000	0.481	0.519
M12.29 Villonodular synovitis (pigmented) (Site unspecified)	0.000	0.481	0.519
M12.28 Villonodular synovitis (pigmented) (Other)	0.000	0.481	0.519
M12.27 Villonodular synovitis (pigmented) (Ankle and foot)	0.000	0.481	0.519
M12.25 Villonodular synovitis (pigmented) (Pelvic region and thigh)	0.000	0.481	0.519
M12.23 Villonodular synovitis (pigmented) (Forearm)	0.000	0.481	0.519
M12.22 Villonodular synovitis (pigmented) (Upper arm)	0.000	0.481	0.519
M12.21 Villonodular synovitis (pigmented) (Shoulder region)	0.000	0.481	0.519
M12.20 Villonodular synovitis (pigmented) (Multiple sites)	0.000	0.481	0.519
M05.29 Rheumatoid vasculitis (Site unspecified)	0.000	0.481	0.518
E07.1 Dyshormogenetic goitre	0.518	0.482	0.000
E07.0 Hypersecretion of calcitonin	0.518	0.482	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.517	0.483	0.000
M05.28 Rheumatoid vasculitis (Other)	0.000	0.484	0.515
M05.27 Rheumatoid vasculitis (Ankle and foot)	0.000	0.484	0.515
M05.26 Rheumatoid vasculitis (Lower leg)	0.000	0.484	0.515
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)	0.000	0.484	0.515
M05.24 Rheumatoid vasculitis (Hand)	0.000	0.484	0.515
M05.23 Rheumatoid vasculitis (Forearm)	0.000	0.484	0.515
M05.22 Rheumatoid vasculitis (Upper arm)	0.000	0.484	0.515
M05.21 Rheumatoid vasculitis (Shoulder region)	0.000	0.484	0.515
M05.20 Rheumatoid vasculitis (Multiple sites)	0.000	0.484	0.515
H00.0 Hordeolum and other deep inflammation of eyelid	0.000	0.484	0.515
M06.19 Adult-onset Still's disease (Site unspecified)	0.000	0.486	0.514
M06.18 Adult-onset Still's disease (Other)	0.000	0.486	0.514
M06.17 Adult-onset Still's disease (Ankle and foot)	0.000	0.486	0.514
M06.16 Adult-onset Still's disease (Lower leg)	0.000	0.486	0.514
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.000	0.486	0.514
M06.14 Adult-onset Still's disease (Hand)	0.000	0.486	0.514
M06.13 Adult-onset Still's disease (Forearm)	0.000	0.486	0.514
M06.12 Adult-onset Still's disease (Upper arm)	0.000	0.486	0.514
M06.11 Adult-onset Still's disease (Shoulder region)	0.000	0.486	0.514
M06.10 Adult-onset Still's disease (Multiple sites)	0.000	0.486	0.514
M06.29 Rheumatoid bursitis (Site unspecified)	0.000	0.486	0.514
M06.28 Rheumatoid bursitis (Other)	0.000	0.486	0.514
M06.27 Rheumatoid bursitis (Ankle and foot)	0.000	0.486	0.514
M06.26 Rheumatoid bursitis (Lower leg)	0.000	0.486	0.514
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.000	0.486	0.514
M06.24 Rheumatoid bursitis (Hand)	0.000	0.486	0.514
M06.23 Rheumatoid bursitis (Forearm)	0.000	0.486	0.514
M06.22 Rheumatoid bursitis (Upper arm)	0.000	0.486	0.514
M06.21 Rheumatoid bursitis (Shoulder region)	0.000	0.486	0.514
M06.20 Rheumatoid bursitis (Multiple sites)	0.000	0.486	0.514
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified	0.514	0.486	0.000
C96.8 Histiocytic sarcoma	0.514	0.486	0.000
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.514	0.486	0.000
C96.6 Unifocal Langerhans-cell histiocytosis	0.514	0.486	0.000
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis	0.514	0.486	0.000
C96.4 Sarcoma of dendritic cells (accessory cells)	0.514	0.486	0.000
C96.3 True histiocytic lymphoma	0.514	0.486	0.000
C96.2 Malignant mast cell tumour	0.514	0.486	0.000
C96.1 Malignant histiocytosis	0.514	0.486	0.000
C96.0 Letterer-Siwe disease	0.514	0.486	0.000
C86.6 Primary cutaneous CD30-positive T-cell proliferations	0.513	0.486	0.000
C86.4 Blastic NK-cell lymphoma	0.513	0.486	0.000
C86.3 Subcutaneous panniculitis-like T-cell lymphoma	0.513	0.486	0.000
C86.2 Enteropathy-type (intestinal) T-cell lymphoma	0.513	0.486	0.000
C86.1 Hepatosplenic T-cell lymphoma	0.513	0.486	0.000
C86.0 Extranodal NK/T-cell lymphoma, nasal type	0.513	0.486	0.000
M05.09 Felty's syndrome (Site unspecified)	0.000	0.486	0.513
M05.08 Felty's syndrome (Other)	0.000	0.486	0.513
M05.07 Felty's syndrome (Ankle and foot)	0.000	0.486	0.513
M05.06 Felty's syndrome (Lower leg)	0.000	0.486	0.513
M05.05 Felty's syndrome (Pelvic region and thigh)	0.000	0.486	0.513
M05.04 Felty's syndrome (Hand)	0.000	0.486	0.513
M05.03 Felty's syndrome (Forearm)	0.000	0.486	0.513
M05.02 Felty's syndrome (Upper arm)	0.000	0.486	0.513
M05.01 Felty's syndrome (Shoulder region)	0.000	0.486	0.513
M05.00 Felty's syndrome (Multiple sites)	0.000	0.486	0.513
M05.19 Rheumatoid lung disease (Site unspecified)	0.000	0.486	0.513
M05.18 Rheumatoid lung disease (Other)	0.000	0.486	0.513
M05.17 Rheumatoid lung disease (Ankle and foot)	0.000	0.486	0.513
M05.16 Rheumatoid lung disease (Lower leg)	0.000	0.486	0.513
M05.15 Rheumatoid lung disease (Pelvic region and thigh)	0.000	0.486	0.513
M05.14 Rheumatoid lung disease (Hand)	0.000	0.486	0.513
M05.13 Rheumatoid lung disease (Forearm)	0.000	0.486	0.513
M05.12 Rheumatoid lung disease (Upper arm)	0.000	0.486	0.513
M05.11 Rheumatoid lung disease (Shoulder region)	0.000	0.486	0.513
M05.10 Rheumatoid lung disease (Multiple sites)	0.000	0.486	0.513
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)	0.000	0.486	0.513
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)	0.000	0.486	0.513
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)	0.000	0.486	0.513
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)	0.000	0.486	0.513
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)	0.000	0.486	0.513
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)	0.000	0.486	0.513
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)	0.000	0.486	0.513
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)	0.000	0.486	0.513
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)	0.000	0.486	0.513
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)	0.000	0.486	0.513
E20.8 Other hypoparathyroidism	0.513	0.487	0.000
E20.1 Pseudohypoparathyroidism	0.513	0.487	0.000
E20.0 Idiopathic hypoparathyroidism	0.513	0.487	0.000
C86.5 Angioimmunoblastic T-cell lymphoma	0.513	0.487	0.000
M09.8 Juvenile arthritis in other diseases classified elsewhere	0.000	0.487	0.513
M09.2 Juvenile arthritis in ulcerative colitis	0.000	0.487	0.513
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]	0.000	0.487	0.513
M09.0 Juvenile arthritis in psoriasis	0.000	0.487	0.513
Q38-Q45 Other congenital malformations of the digestive system	0.513	0.487	0.000
M31.3 Wegener's granulomatosis	0.000	0.489	0.511
E03.8 Other specified hypothyroidism	0.511	0.489	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.510	0.489	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.510	0.489	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.510	0.489	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.510	0.489	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.510	0.489	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.510	0.489	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.510	0.489	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.510	0.489	0.000
E12.9 Without complications	0.510	0.490	0.000
E12.8 With unspecified complications	0.510	0.490	0.000
E12.7 With multiple complications	0.510	0.490	0.000
E12.6 With other specified complications	0.510	0.490	0.000
E12.5 With peripheral circulatory complications	0.510	0.490	0.000
E12.4 With neurological complications	0.510	0.490	0.000
E12.3 With ophthalmic complications	0.510	0.490	0.000
E12.2 With renal complications	0.510	0.490	0.000
E12.1 With ketoacidosis	0.510	0.490	0.000
E12.0 With coma	0.510	0.490	0.000
E28.3 Primary ovarian failure	0.505	0.495	0.000
E30.9 Disorder of puberty, unspecified	0.503	0.497	0.000
E30.8 Other disorders of puberty	0.503	0.497	0.000
E30.1 Precocious puberty	0.503	0.497	0.000
E30.0 Delayed puberty	0.503	0.497	0.000
E32.9 Disease of thymus, unspecified	0.503	0.497	0.000
E32.8 Other diseases of thymus	0.503	0.497	0.000
E32.1 Abscess of thymus	0.503	0.497	0.000
E32.0 Persistent hyperplasia of thymus	0.503	0.497	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.503	0.497	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.503	0.497	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.503	0.497	0.000
E31.9 Polyglandular dysfunction, unspecified	0.502	0.498	0.000
E31.8 Other polyglandular dysfunction	0.502	0.498	0.000
E31.1 Polyglandular hyperfunction	0.502	0.498	0.000
E31.0 Autoimmune polyglandular failure	0.500	0.500	0.000
M20.0 Deformity of finger(s)	0.000	0.501	0.499
M07 Psoriatic and enteropathic arthropathies	0.000	0.502	0.498
C90.1 Plasma cell leukaemia	0.495	0.505	0.000
E14.7 With multiple complications	0.495	0.505	0.000
E14.0 With coma	0.495	0.505	0.000
M10 Gout	0.000	0.505	0.495
E06 Thyroiditis	0.494	0.506	0.000
E03.5 Myxoedema coma	0.493	0.506	0.000
E03.4 Atrophy of thyroid (acquired)	0.493	0.506	0.000
E03.3 Postinfectious hypothyroidism	0.493	0.506	0.000
E14.2 Withrenal complications	0.493	0.507	0.000
Q50-Q56 Congenital malformations of genital organs	0.492	0.508	0.000
K90.8 Other intestinal malabsorption	0.487	0.513	0.000
C91.5 Adult T-cell leukaemia	0.484	0.516	0.000
M35.8 Other specified systemic involvement of connective tissue	0.000	0.519	0.481
E34.0 Carcinoid syndrome	0.480	0.520	0.000
M14.8 Arthropathies in other specified diseases classified elsewhere	0.000	0.522	0.478
Q43 Other congenital malformations of intestine	0.476	0.524	0.000
M12.57 Traumatic arthropathy (Ankle and foot)	0.000	0.526	0.474
M08.8 Other juvenile arthritis	0.000	0.528	0.472
M08.4 Pauciarticular juvenile arthritis	0.000	0.528	0.472
M08.3 Juvenile polyarthritis (seronegative)	0.000	0.528	0.472
M08.2 Juvenile arthritis with systemic onset	0.000	0.528	0.472
M08.1 Juvenile ankylosing spondylitis	0.000	0.528	0.472
M08.0 Juvenile rheumatoid arthritis	0.000	0.528	0.472
M11 Other crystal arthropathies	0.001	0.529	0.470
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]	0.470	0.530	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations