TreeWAS – Variant ID: rs9268481

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	1.000	0.000	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	1.000	0.000	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	1.000	0.000	0.000
E03.9 Hypothyroidism, unspecified	1.000	0.000	0.000
E10.9 Without complications	1.000	0.000	0.000
E10.3 With ophthalmic complications	1.000	0.000	0.000
J45.9 Asthma, unspecified	1.000	0.000	0.000
K51.9 Ulcerative colitis, unspecified	0.000	0.000	1.000
K90.0 Coeliac disease	0.000	0.000	1.000
M05.9 Seropositive rheumatoid arthritis, unspecified	1.000	0.000	0.000
M06.9 Rheumatoid arthritis, unspecified	1.000	0.000	0.000
M35.3 Polymyalgia rheumatica	1.000	0.000	0.000
C44 Other malignant neoplasms of skin	0.000	0.000	1.000
E10 Insulin-dependent diabetes mellitus	1.000	0.000	0.000
G35 Multiple sclerosis	0.000	0.000	1.000
M06 Other rheumatoid arthritis	1.000	0.000	0.000
E10-E14 Diabetes mellitus	1.000	0.000	0.000
M05-M14 Inflammatory polyarthropathies	1.000	0.000	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	1.000	0.000	0.000
M20-M25 Other joint disorders	1.000	0.000	0.000
C44.3 Skin of other and unspecified parts of face	0.000	0.000	1.000
M05 Seropositive rheumatoid arthritis	1.000	0.000	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	1.000	0.000	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	1.000	0.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000	0.000
J33.9 Nasal polyp, unspecified	1.000	0.000	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	1.000	0.000	0.000
J33 Nasal polyp	1.000	0.000	0.000
E10.1 With ketoacidosis	1.000	0.000	0.000
M35 Other systemic involvement of connective tissue	1.000	0.000	0.000
M06.3 Rheumatoid nodule	1.000	0.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000	0.000
E03 Other hypothyroidism	0.999	0.001	0.000
E00-E07 Disorders of thyroid gland	0.999	0.001	0.000
M31 Other necrotising vasculopathies	0.999	0.001	0.000
M31.6 Other giant cell arteritis	0.998	0.002	0.000
C44.7 Skin of lower limb, including hip	0.000	0.002	0.998
K51 Ulcerative colitis	0.000	0.003	0.997
J45 Asthma	0.997	0.003	0.000
N47 Redundant prepuce, phimosis and paraphimosis	0.997	0.003	0.000
M06.34 Rheumatoid nodule (Hand)	0.997	0.003	0.000
N48 Other disorders of penis	0.996	0.004	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.996	0.004	0.000
N40-N51 Diseases of male genital organs	0.996	0.004	0.000
J33.0 Polyp of nasal cavity	0.995	0.005	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.995	0.005	0.000
E11 Non-insulin-dependent diabetes mellitus	0.995	0.005	0.000
J40-J47 Chronic lower respiratory diseases	0.994	0.006	0.000
C44.4 Skin of scalp and neck	0.000	0.007	0.993
E10.4 With neurological complications	0.993	0.007	0.000
E16 Other disorders of pancreatic internal secretion	0.992	0.008	0.000
E11.9 Without complications	0.991	0.009	0.000
E14 Unspecified diabetes mellitus	0.991	0.009	0.000
N48.6 Balanitis xerotica obliterans	0.990	0.010	0.000
E16.2 Hypoglycaemia, unspecified	0.987	0.013	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.986	0.014	0.000
N48.0 Leukoplakia of penis	0.982	0.018	0.000
C44.6 Skin of upper limb, including shoulder	0.000	0.019	0.981
M45-M49 Spondylopathies	0.980	0.020	0.000
M06.4 Inflammatory polyarthropathy	0.979	0.021	0.000
K51.4 Pseudopolyposis of colon	0.000	0.023	0.977
E14.3 With ophthalmic complications	0.976	0.024	0.000
J30-J39 Other diseases of upper respiratory tract	0.976	0.024	0.000
Chapter X Diseases of the respiratory system	0.974	0.026	0.000
M20 Acquired deformities of fingers and toes	0.974	0.026	0.000
J46 Status asthmaticus	0.973	0.027	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.965	0.035	0.000
C21.0 Anus, unspecified	0.959	0.041	0.000
M20.4 Other hammer toe(s) (acquired)	0.957	0.043	0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.954	0.046	0.000
C21 Malignant neoplasm of anus and anal canal	0.954	0.046	0.000
C21.1 Anal canal	0.953	0.047	0.000
C44.2 Skin of ear and external auricular canal	0.000	0.050	0.950
N49 Inflammatory disorders of male genital organs, not elsewhere classified	0.944	0.056	0.000
E10.5 With peripheral circulatory complications	0.937	0.063	0.000
E10.6 With other specified complications	0.936	0.064	0.000
M06.32 Rheumatoid nodule (Upper arm)	0.932	0.068	0.000
M48 Other spondylopathies	0.931	0.069	0.000
J42 Unspecified chronic bronchitis	0.926	0.074	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.924	0.076	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.920	0.080	0.000
M45 Ankylosing spondylitis	0.918	0.082	0.000
J43 Emphysema	0.918	0.082	0.000
M06.0 Seronegative rheumatoid arthritis	0.917	0.083	0.000
M12 Other specific arthropathies	0.913	0.087	0.000
E10.0 With coma	0.913	0.087	0.000
M14 Arthropathies in other diseases classified elsewhere	0.905	0.095	0.000
M30 Polyarteritis nodosa and related conditions	0.900	0.100	0.000
# Top node	0.898	0.102	0.000
M21 Other acquired deformities of limbs	0.898	0.102	0.000
K51.2 Ulcerative (chronic) proctitis	0.000	0.103	0.897
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.894	0.106	0.000
J43.9 Emphysema, unspecified	0.888	0.112	0.000
N49.2 Inflammatory disorders of scrotum	0.887	0.113	0.000
M48.0 Spinal stenosis	0.886	0.114	0.000
K51.5 Mucosal proctocolitis	0.000	0.117	0.883
M20.6 Acquired deformity of toe(s), unspecified	0.883	0.117	0.000
J33.8 Other polyp of sinus	0.876	0.124	0.000
N48.9 Disorder of penis, unspecified	0.875	0.125	0.000
C44.9 Malignant neoplasm of skin, unspecified	0.000	0.126	0.874
K51.0 Ulcerative (chronic) enterocolitis	0.000	0.134	0.866
E13 Other specified diabetes mellitus	0.865	0.135	0.000
E10.8 With unspecified complications	0.865	0.135	0.000
E14.6 With other specified complications	0.863	0.137	0.000
E06 Thyroiditis	0.862	0.138	0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.859	0.141	0.000
Chapter XIV Diseases of the genitourinary system	0.858	0.142	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	0.857	0.143	0.000
M48.06 Spinal stenosis (Lumbar region)	0.851	0.149	0.000
J95-J99 Other diseases of the respiratory system	0.844	0.156	0.000
M12.3 Palindromic rheumatism	0.844	0.156	0.000
M06.30 Rheumatoid nodule (Multiple sites)	0.843	0.157	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.842	0.158	0.000
M31.7 Microscopic polyangiitis	0.842	0.158	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.839	0.161	0.000
M05.8 Other seropositive rheumatoid arthritis	0.839	0.161	0.000
M21.1 Varus deformity, not elsewhere classified	0.837	0.163	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.837	0.163	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.834	0.166	0.000
M35.1 Other overlap syndromes	0.832	0.168	0.000
J35 Chronic diseases of tonsils and adenoids	0.830	0.170	0.000
N48.2 Other inflammatory disorders of penis	0.827	0.173	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.827	0.173	0.000
M05.1 Rheumatoid lung disease	0.825	0.175	0.000
E03.8 Other specified hypothyroidism	0.824	0.176	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.081	0.177	0.742
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.819	0.181	0.000
J99 Respiratory disorders in diseases classified elsewhere	0.814	0.186	0.000
N42 Other disorders of prostate	0.812	0.188	0.000
M00-M03 Infectious arthropathies	0.812	0.188	0.000
M14.6 Neuropathic arthropathy	0.811	0.189	0.000
N48.5 Ulcer of penis	0.810	0.190	0.000
J45.1 Nonallergic asthma	0.805	0.195	0.000
E11.6 With other specified complications	0.803	0.197	0.000
M21.16 Varus deformity, not elsewhere classified (Lower leg)	0.803	0.197	0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.799	0.201	0.000
K51.8 Other ulcerative colitis	0.000	0.202	0.798
M46 Other inflammatory spondylopathies	0.798	0.202	0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.795	0.205	0.000
E14.9 Without complications	0.794	0.206	0.000
M86-M90 Other osteopathies	0.793	0.207	0.000
M08 Juvenile arthritis	0.792	0.208	0.000
E16.1 Other hypoglycaemia	0.792	0.208	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.791	0.209	0.000
N30 Cystitis	0.788	0.212	0.000
J38.3 Other diseases of vocal cords	0.788	0.212	0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.787	0.213	0.000
N30.2 Other chronic cystitis	0.786	0.214	0.000
M20.0 Deformity of finger(s)	0.783	0.217	0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.782	0.218	0.000
N30-N39 Other diseases of urinary system	0.781	0.219	0.000
M35.8 Other specified systemic involvement of connective tissue	0.774	0.226	0.000
J33.1 Polypoid sinus degeneration	0.773	0.227	0.000
N49.8 Inflammatory disorders of other specified male genital organs	0.773	0.227	0.000
E10.2 With renal complications	0.770	0.230	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.002	0.233	0.765
J99.0 Rheumatoid lung disease	0.765	0.235	0.000
M20.5 Other deformities of toe(s) (acquired)	0.764	0.236	0.000
M65-M68 Disorders of synovium and tendon	0.763	0.237	0.000
E03.1 Congenital hypothyroidism without goitre	0.762	0.238	0.000
M49 Spondylopathies in diseases classified elsewhere	0.762	0.238	0.000
M48.07 Spinal stenosis (Lumbosacral region)	0.760	0.240	0.000
M48.02 Spinal stenosis (Cervical region)	0.759	0.241	0.000
Z93.2 Ileostomy status	0.000	0.242	0.758
J35.1 Hypertrophy of tonsils	0.757	0.243	0.000
E13.9 Without complications	0.755	0.245	0.000
M31.9 Necrotising vasculopathy, unspecified	0.755	0.245	0.000
E14.2 Withrenal complications	0.755	0.245	0.000
N44 Torsion of testis	0.754	0.246	0.000
M21.3 Wrist or foot drop (acquired)	0.753	0.247	0.000
E11.3 With ophthalmic complications	0.751	0.249	0.000
N42.2 Atrophy of prostate	0.751	0.249	0.000
M48.5 Collapsed vertebra, not elsewhere classified	0.750	0.250	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.750	0.250	0.000
M31.4 Aortic arch syndrome [Takayasu]	0.750	0.250	0.000
M60-M63 Disorders of muscles	0.749	0.251	0.000
E05.9 Thyrotoxicosis, unspecified	0.001	0.252	0.747
N51 Disorders of male genital organs in diseases classified elsewhere	0.747	0.253	0.000
M30.0 Polyarteritis nodosa	0.746	0.254	0.000
M12.39 Palindromic rheumatism (Site unspecified)	0.746	0.254	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.745	0.255	0.000
J99.8 Respiratory disorders in other diseases classified elsewhere	0.744	0.256	0.000
E06.3 Autoimmune thyroiditis	0.742	0.258	0.000
E10.7 With multiple complications	0.742	0.258	0.000
E11.4 With neurological complications	0.740	0.260	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.737	0.263	0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)	0.737	0.263	0.000
M06.8 Other specified rheumatoid arthritis	0.735	0.265	0.000
M06.46 Inflammatory polyarthropathy (Lower leg)	0.735	0.265	0.000
J45.8 Mixed asthma	0.733	0.267	0.000
E11.1 With ketoacidosis	0.732	0.268	0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.732	0.268	0.000
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)	0.724	0.276	0.000
M12.30 Palindromic rheumatism (Multiple sites)	0.723	0.277	0.000
E11.0 With coma	0.722	0.278	0.000
M14.2 Diabetic arthropathy	0.720	0.280	0.000
N42.9 Disorder of prostate, unspecified	0.719	0.281	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.717	0.283	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.717	0.283	0.000
C44.8 Overlapping lesion of skin	0.000	0.283	0.717
M06.2 Rheumatoid bursitis	0.717	0.283	0.000
M06.1 Adult-onset Still's disease	0.717	0.283	0.000
E12 Malnutrition-related diabetes mellitus	0.717	0.283	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.717	0.283	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.717	0.283	0.000
M05.2 Rheumatoid vasculitis	0.717	0.283	0.000
M05.0 Felty's syndrome	0.717	0.283	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.717	0.283	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.717	0.283	0.000
M35.5 Multifocal fibrosclerosis	0.717	0.283	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.717	0.283	0.000
M06.39 Rheumatoid nodule (Site unspecified)	0.717	0.283	0.000
M06.38 Rheumatoid nodule (Other)	0.717	0.283	0.000
M06.36 Rheumatoid nodule (Lower leg)	0.717	0.283	0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.717	0.283	0.000
M06.33 Rheumatoid nodule (Forearm)	0.717	0.283	0.000
M06.31 Rheumatoid nodule (Shoulder region)	0.717	0.283	0.000
E03.5 Myxoedema coma	0.717	0.283	0.000
E03.4 Atrophy of thyroid (acquired)	0.717	0.283	0.000
E03.3 Postinfectious hypothyroidism	0.717	0.283	0.000
J45.0 Predominantly allergic asthma	0.717	0.283	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.716	0.284	0.000
E00 Congenital iodine-deficiency syndrome	0.716	0.284	0.000
M31.2 Lethal midline granuloma	0.716	0.284	0.000
M31.0 Hypersensitivity angiitis	0.716	0.284	0.000
E11.5 With peripheral circulatory complications	0.715	0.285	0.000
E15 Nondiabetic hypoglycaemic coma	0.714	0.286	0.000
E11.7 With multiple complications	0.713	0.287	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.712	0.288	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.712	0.288	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.712	0.288	0.000
E16.4 Abnormal secretion of gastrin	0.712	0.288	0.000
E16.3 Increased secretion of glucagon	0.712	0.288	0.000
N48.4 Impotence of organic origin	0.711	0.289	0.000
E14.7 With multiple complications	0.710	0.290	0.000
E14.0 With coma	0.710	0.290	0.000
E11.8 With unspecified complications	0.710	0.290	0.000
M21.6 Other acquired deformities of ankle and foot	0.707	0.293	0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.707	0.293	0.000
C21.8 Overlapping lesion of rectum, anus and anal canal	0.706	0.294	0.000
E14.8 With unspecified complications	0.706	0.294	0.000
M21.9 Acquired deformity of limb, unspecified	0.706	0.294	0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.705	0.295	0.000
M06.48 Inflammatory polyarthropathy (Other)	0.702	0.298	0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.702	0.298	0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.702	0.298	0.000
M06.44 Inflammatory polyarthropathy (Hand)	0.702	0.298	0.000
M06.43 Inflammatory polyarthropathy (Forearm)	0.702	0.298	0.000
M06.42 Inflammatory polyarthropathy (Upper arm)	0.702	0.298	0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.702	0.298	0.000
M05.19 Rheumatoid lung disease (Site unspecified)	0.700	0.300	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.698	0.302	0.000
E14.5 With peripheral circulatory complications	0.694	0.306	0.000
J32 Chronic sinusitis	0.691	0.309	0.000
J38.6 Stenosis of larynx	0.691	0.309	0.000
N48.1 Balanoposthitis	0.689	0.311	0.000
M31.8 Other specified necrotising vasculopathies	0.684	0.316	0.000
C21.2 Cloacogenic zone	0.684	0.316	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.684	0.316	0.000
M48.56 Collapsed vertebra, not elsewhere classified (Lumbar region)	0.683	0.317	0.000
M12.2 Villonodular synovitis (pigmented)	0.683	0.317	0.000
M46.1 Sacro-iliitis, not elsewhere classified	0.679	0.321	0.000
M00 Pyogenic arthritis	0.679	0.321	0.000
M99 Biomechanical lesions, not elsewhere classified	0.679	0.321	0.000
E06.5 Other chronic thyroiditis	0.678	0.322	0.000
J38.5 Laryngeal spasm	0.678	0.322	0.000
N49.9 Inflammatory disorder of unspecified male genital organ	0.677	0.323	0.000
N49.1 Inflammatory disorders of spermatic cord, tunica vaginalis and vas deferens	0.677	0.323	0.000
N49.0 Inflammatory disorders of seminal vesicle	0.677	0.323	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.676	0.324	0.000
J35.8 Other chronic diseases of tonsils and adenoids	0.674	0.326	0.000
K51.1 Ulcerative (chronic) ileocolitis	0.000	0.328	0.671
K51.3 Ulcerative (chronic) rectosigmoiditis	0.000	0.329	0.671
N35 Urethral stricture	0.670	0.330	0.000
N45 Orchitis and epididymitis	0.669	0.331	0.000
J35.2 Hypertrophy of adenoids	0.668	0.332	0.000
M48.4 Fatigue fracture of vertebra	0.667	0.332	0.000
M48.3 Traumatic spondylopathy	0.667	0.332	0.000
M48.2 Kissing spine	0.667	0.332	0.000
M48.1 Ankylosing hyperostosis [Forestier]	0.667	0.332	0.000
M20.1 Hallux valgus (acquired)	0.667	0.333	0.000
M65 Synovitis and tenosynovitis	0.667	0.333	0.000
N30.0 Acute cystitis	0.664	0.336	0.000
N30.9 Cystitis, unspecified	0.663	0.337	0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.658	0.342	0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.658	0.342	0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.658	0.342	0.000
M45.X4 Ankylosing spondylitis (Thoracic region)	0.658	0.342	0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.658	0.342	0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.658	0.342	0.000
J43.1 Panlobular emphysema	0.658	0.342	0.000
J43.0 MacLeod's syndrome	0.658	0.342	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.658	0.342	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.658	0.342	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.658	0.342	0.000
M91-M94 Chondropathies	0.657	0.343	0.000
N30.1 Interstitial cystitis (chronic)	0.655	0.345	0.000
M12.8 Other specific arthropathies, not elsewhere classified	0.655	0.345	0.000
M12.5 Traumatic arthropathy	0.655	0.345	0.000
M12.4 Intermittent hydrarthrosis	0.655	0.345	0.000
M12.1 Kaschin-Beck disease	0.655	0.345	0.000
M12.0 Chronic postrheumatic arthropathy [Jaccoud]	0.655	0.345	0.000
M88 Paget's disease of bone [osteitis deformans]	0.654	0.346	0.000
N25-N29 Other disorders of kidney and ureter	0.652	0.348	0.000
M35.2 Behcet's disease	0.652	0.348	0.000
E13.3 With ophthalmic complications	0.651	0.349	0.000
M48.8 Other specified spondylopathies	0.651	0.349	0.000
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.650	0.350	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.649	0.350	0.000
J38.0 Paralysis of vocal cords and larynx	0.649	0.351	0.000
M14.8 Arthropathies in other specified diseases classified elsewhere	0.649	0.351	0.000
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders	0.649	0.351	0.000
M14.4 Arthropathy in amyloidosis	0.649	0.351	0.000
M14.3 Lipoid dermatoarthritis	0.649	0.351	0.000
M14.1 Crystal arthropathy in other metabolic disorders	0.649	0.351	0.000
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders	0.649	0.351	0.000
M48.9 Spondylopathy, unspecified	0.646	0.354	0.000
M30.8 Other conditions related to polyarteritis nodosa	0.645	0.354	0.000
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]	0.645	0.354	0.000
M30.2 Juvenile polyarteritis	0.645	0.354	0.000
J41 Simple and mucopurulent chronic bronchitis	0.644	0.356	0.000
E07 Other disorders of thyroid	0.643	0.357	0.000
M46.4 Discitis, unspecified	0.642	0.358	0.000
M08.0 Juvenile rheumatoid arthritis	0.642	0.358	0.000
J37 Chronic laryngitis and laryngotracheitis	0.640	0.360	0.000
E14.4 With neurological complications	0.639	0.361	0.000
M48.05 Spinal stenosis (Thoracolumbar region)	0.635	0.365	0.000
M48.03 Spinal stenosis (Cervicothoracic region)	0.635	0.365	0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)	0.635	0.365	0.000
E14.1 With ketoacidosis	0.635	0.365	0.000
N30.3 Trigonitis	0.632	0.368	0.000
E06.1 Subacute thyroiditis	0.631	0.369	0.000
M21.2 Flexion deformity	0.631	0.369	0.000
M34 Systemic sclerosis	0.629	0.371	0.000
J38.4 Oedema of larynx	0.627	0.373	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.627	0.373	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.622	0.378	0.000
E13.8 With unspecified complications	0.620	0.379	0.000
E13.7 With multiple complications	0.620	0.379	0.000
E13.6 With other specified complications	0.620	0.379	0.000
E13.5 With peripheral circulatory complications	0.620	0.379	0.000
E13.4 With neurological complications	0.620	0.379	0.000
E13.2 With renal complications	0.620	0.379	0.000
E13.1 With ketoacidosis	0.620	0.379	0.000
E13.0 With coma	0.620	0.379	0.000
N60-N64 Disorders of breast	0.619	0.381	0.000
E06.4 Drug-induced thyroiditis	0.618	0.382	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.618	0.382	0.000
E06.0 Acute thyroiditis	0.618	0.382	0.000
M31.1 Thrombotic microangiopathy	0.616	0.384	0.000
M46.3 Infection of intervertebral disk (pyogenic)	0.614	0.386	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.000	0.386	0.613
D68 Other coagulation defects	0.000	0.387	0.613
G35-G37 Demyelinating diseases of the central nervous system	0.003	0.387	0.610
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)	0.613	0.387	0.000
M33 Dermatopolymyositis	0.612	0.388	0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.612	0.388	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.610	0.390	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.002	0.392	0.606
C44.0 Skin of lip	0.000	0.394	0.606
J96 Respiratory failure, not elsewhere classified	0.605	0.395	0.000
M49.5 Collapsed vertebra in diseases classified elsewhere	0.605	0.395	0.000
M12.38 Palindromic rheumatism (Other)	0.605	0.395	0.000
M12.37 Palindromic rheumatism (Ankle and foot)	0.605	0.395	0.000
M12.36 Palindromic rheumatism (Lower leg)	0.605	0.395	0.000
M12.35 Palindromic rheumatism (Pelvic region and thigh)	0.605	0.395	0.000
M12.34 Palindromic rheumatism (Hand)	0.605	0.395	0.000
M12.33 Palindromic rheumatism (Forearm)	0.605	0.395	0.000
M12.32 Palindromic rheumatism (Upper arm)	0.605	0.395	0.000
M12.31 Palindromic rheumatism (Shoulder region)	0.605	0.395	0.000
M60 Myositis	0.605	0.395	0.000
M32 Systemic lupus erythematosus	0.604	0.396	0.000
N60 Benign mammary dysplasia	0.603	0.397	0.000
J32.9 Chronic sinusitis, unspecified	0.603	0.397	0.000
M45.X6 Ankylosing spondylitis (Lumbar region)	0.602	0.398	0.000
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)	0.602	0.398	0.000
M05.88 Other seropositive rheumatoid arthritis (Other)	0.602	0.398	0.000
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)	0.602	0.398	0.000
M05.86 Other seropositive rheumatoid arthritis (Lower leg)	0.602	0.398	0.000
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)	0.602	0.398	0.000
M05.84 Other seropositive rheumatoid arthritis (Hand)	0.602	0.398	0.000
M05.83 Other seropositive rheumatoid arthritis (Forearm)	0.602	0.398	0.000
M05.82 Other seropositive rheumatoid arthritis (Upper arm)	0.602	0.398	0.000
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)	0.602	0.398	0.000
J43.2 Centrilobular emphysema	0.602	0.398	0.000
M21.19 Varus deformity, not elsewhere classified (Site unspecified)	0.600	0.400	0.000
M21.18 Varus deformity, not elsewhere classified (Other)	0.600	0.400	0.000
M21.15 Varus deformity, not elsewhere classified (Pelvic region and thigh)	0.600	0.400	0.000
M21.14 Varus deformity, not elsewhere classified (Hand)	0.600	0.400	0.000
M21.13 Varus deformity, not elsewhere classified (Forearm)	0.600	0.400	0.000
M21.12 Varus deformity, not elsewhere classified (Upper arm)	0.600	0.400	0.000
M21.11 Varus deformity, not elsewhere classified (Shoulder region)	0.600	0.400	0.000
M21.10 Varus deformity, not elsewhere classified (Multiple sites)	0.600	0.400	0.000
N41 Inflammatory diseases of prostate	0.600	0.400	0.000
N35.9 Urethral stricture, unspecified	0.599	0.401	0.000
M65.4 Radial styloid tenosynovitis [de Quervain]	0.597	0.403	0.000
J35.3 Hypertrophy of tonsils with hypertrophy of adenoids	0.595	0.405	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.595	0.405	0.000
D68.8 Other specified coagulation defects	0.000	0.407	0.593
M05.18 Rheumatoid lung disease (Other)	0.592	0.408	0.000
M05.17 Rheumatoid lung disease (Ankle and foot)	0.592	0.408	0.000
M05.16 Rheumatoid lung disease (Lower leg)	0.592	0.408	0.000
M05.15 Rheumatoid lung disease (Pelvic region and thigh)	0.592	0.408	0.000
M05.14 Rheumatoid lung disease (Hand)	0.592	0.408	0.000
M05.13 Rheumatoid lung disease (Forearm)	0.592	0.408	0.000
M05.12 Rheumatoid lung disease (Upper arm)	0.592	0.408	0.000
M05.11 Rheumatoid lung disease (Shoulder region)	0.592	0.408	0.000
M05.10 Rheumatoid lung disease (Multiple sites)	0.592	0.408	0.000
E05.5 Thyroid crisis or storm	0.058	0.410	0.532
E05.4 Thyrotoxicosis factitia	0.058	0.410	0.532
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.058	0.410	0.532
M46.0 Spinal enthesopathy	0.590	0.410	0.000
M31.3 Wegener's granulomatosis	0.589	0.411	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.587	0.413	0.000
C43-C44 Melanoma and other malignant neoplasms of skin	0.048	0.413	0.539
N60.8 Other benign mammary dysplasias	0.586	0.414	0.000
M99.5 Intervertebral disk stenosis of neural canal	0.584	0.416	0.000
E06.9 Thyroiditis, unspecified	0.583	0.417	0.000
N42.3 Dysplasia of prostate	0.582	0.417	0.000
M03 Postinfective and reactive arthropathies in diseases classified elsewhere	0.582	0.418	0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere	0.582	0.418	0.000
M02 Reactive arthropathies	0.580	0.420	0.000
J38.2 Nodules of vocal cords	0.580	0.420	0.000
M13 Other arthritis	0.580	0.420	0.000
M86 Osteomyelitis	0.579	0.421	0.000
M21.8 Other specified acquired deformities of limbs	0.579	0.421	0.000
K50-K52 Noninfective enteritis and colitis	0.000	0.421	0.579
M46.2 Osteomyelitis of vertebra	0.578	0.422	0.000
E40-E46 Malnutrition	0.577	0.423	0.000
M11 Other crystal arthropathies	0.575	0.425	0.000
M40-M43 Deforming dorsopathies	0.575	0.425	0.000
M66 Spontaneous rupture of synovium and tendon	0.574	0.425	0.000
M45.X2 Ankylosing spondylitis (Cervical region)	0.573	0.427	0.000
M46.8 Other specified inflammatory spondylopathies	0.572	0.427	0.000
M46.5 Other infective spondylopathies	0.572	0.427	0.000
M89 Other disorders of bone	0.571	0.429	0.000
E50-E64 Other nutritional deficiencies	0.570	0.429	0.000
D60-D64 Aplastic and other anaemias	0.000	0.430	0.570
J95 Postprocedural respiratory disorders, not elsewhere classified	0.570	0.430	0.000
M21.67 Other acquired deformities of ankle and foot-Ankle/foot	0.570	0.430	0.000
D61.9 Aplastic anaemia, unspecified	0.000	0.431	0.569
N51.2 Balanitis in diseases classified elsewhere	0.568	0.432	0.000
M21.97 Acquired deformity of limb, unspecified (Ankle and foot)	0.568	0.432	0.000
M08.9 Juvenile arthritis, unspecified	0.568	0.432	0.000
M08.8 Other juvenile arthritis	0.568	0.432	0.000
M08.4 Pauciarticular juvenile arthritis	0.568	0.432	0.000
M08.3 Juvenile polyarthritis (seronegative)	0.568	0.432	0.000
M08.2 Juvenile arthritis with systemic onset	0.568	0.432	0.000
M08.1 Juvenile ankylosing spondylitis	0.568	0.432	0.000
D61 Other aplastic anaemias	0.000	0.433	0.567
M46.18 Sacroiliitis, not elsewhere classified-Sacral/sacrococ	0.566	0.434	0.000
M96.1 Postlaminectomy syndrome, not elsewhere classified	0.562	0.438	0.000
D68.6 Other Thrombophilia	0.000	0.438	0.562
J32.2 Chronic ethmoidal sinusitis	0.562	0.438	0.000
N37 Urethral disorders in diseases classified elsewhere	0.560	0.440	0.000
N33 Bladder disorders in diseases classified elsewhere	0.560	0.440	0.000
M87 Osteonecrosis	0.557	0.443	0.000
D69 Purpura and other haemorrhagic conditions	0.000	0.443	0.557
M48.04 Spinal stenosis (Thoracic region)	0.554	0.446	0.000
D55-D59 Haemolytic anaemias	0.001	0.447	0.552
J30 Vasomotor and allergic rhinitis	0.551	0.449	0.000
M90 Osteopathies in diseases classified elsewhere	0.550	0.450	0.000
M46.46 Discitis, unspecified (Lumbar region)	0.549	0.451	0.000
N48.3 Priapism	0.548	0.451	0.000
K52 Other non-infective gastro-enteritis and colitis	0.000	0.452	0.548
J36 Peritonsillar abscess	0.548	0.452	0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.547	0.453	0.000
N60.0 Solitary cyst of breast	0.547	0.453	0.000
M49.8 Spondylopathy in other diseases classified elsewhere	0.546	0.454	0.000
M49.4 Neuropathic spondylopathy	0.546	0.454	0.000
M49.3 Spondylopathy in other infectious and parasitic diseases classified elsewhere	0.546	0.454	0.000
M49.2 Enterobacterial spondylitis	0.546	0.454	0.000
M49.1 Brucella spondylitis	0.546	0.454	0.000
M49.0 Tuberculosis of spine	0.546	0.454	0.000
M00.9 Pyogenic arthritis, unspecified	0.546	0.454	0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.545	0.455	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.545	0.455	0.000
N27 Small kidney of unknown cause	0.544	0.456	0.000
M12.24 Villonodular synovitis (pigmented) (Hand)	0.544	0.456	0.000
M88.9 Paget's disease of bone, unspecified	0.544	0.456	0.000
M21.4 Flat foot [pes planus] (acquired)	0.542	0.458	0.000
G37 Other demyelinating diseases of central nervous system	0.001	0.459	0.540
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.062	0.460	0.478
M21.39 Wrist or foot drop (acquired)-Site unspec	0.540	0.460	0.000
M21.38 Wrist or foot drop (acquired)-Other	0.540	0.460	0.000
M21.36 Wrist or foot drop (acquired)-Lower leg	0.540	0.460	0.000
M21.35 Wrist or foot drop (acquired)-Pelvic/thigh	0.540	0.460	0.000
M21.34 Wrist or foot drop (acquired) (Hand)	0.540	0.460	0.000
M21.33 Wrist or foot drop (acquired) (Forearm)	0.540	0.460	0.000
M21.32 Wrist or foot drop (acquired)-Upper arm	0.540	0.460	0.000
M21.31 Wrist or foot drop (acquired)-Shldr region	0.540	0.460	0.000
M21.30 Wrist or foot drop (acquired) (Multiple sites)	0.540	0.460	0.000
J35.9 Chronic disease of tonsils and adenoids, unspecified	0.539	0.461	0.000
D68.5 Primary Thrombophilia	0.000	0.461	0.539
J00-J06 Acute upper respiratory infections	0.538	0.462	0.000
M48.59 Collapsed vertebra, not elsewhere classified (Site unspecified)	0.538	0.462	0.000
M48.58 Collapsed vertebra, not elsewhere classified (Sacral and sacrococcygeal region)	0.538	0.462	0.000
M48.57 Collapsed vertebra, not elsewhere classified (Lumbosacral region)	0.538	0.462	0.000
M48.53 Collapsed vertebra, not elsewhere classified (Cervicothoracic region)	0.538	0.462	0.000
M48.52 Collapsed vertebra, not elsewhere classified (Cervical region)	0.538	0.462	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations