TreeWAS – Variant ID: rs9268659

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.000	1.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.000	1.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.000	1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.000	1.000
E05.0 Thyrotoxicosis with diffuse goitre	1.000	0.000	0.000
J45.9 Asthma, unspecified	0.000	0.000	1.000
K90.0 Coeliac disease	1.000	0.000	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.000	0.000	1.000
M06.9 Rheumatoid arthritis, unspecified	0.000	0.000	1.000
G35 Multiple sclerosis	1.000	0.000	0.000
M06 Other rheumatoid arthritis	0.000	0.000	1.000
R31 Unspecified haematuria	0.000	0.000	1.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.000	0.000	1.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	1.000	0.000	0.000
E05 Thyrotoxicosis [hyperthyroidism]	1.000	0.000	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.000	1.000
E10 Insulin-dependent diabetes mellitus	0.000	0.000	1.000
E03.9 Hypothyroidism, unspecified	0.000	0.000	1.000
M05 Seropositive rheumatoid arthritis	0.000	0.000	1.000
E10.9 Without complications	0.000	0.000	1.000
E00-E07 Disorders of thyroid gland	0.997	0.000	0.003
Chapter IV Endocrine, nutritional and metabolic diseases	0.997	0.001	0.002
M05-M14 Inflammatory polyarthropathies	0.000	0.001	0.999
M06.3 Rheumatoid nodule	0.000	0.001	0.999
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.999	0.001	0.000
J33.9 Nasal polyp, unspecified	0.000	0.001	0.999
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.000	0.001	0.999
M06.0 Seronegative rheumatoid arthritis	0.000	0.002	0.998
E20-E35 Disorders of other endocrine glands	0.998	0.002	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.998	0.002	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	0.000	0.004	0.996
E27 Other disorders of adrenal gland	0.995	0.005	0.000
D68 Other coagulation defects	0.994	0.006	0.000
Chapter VI Diseases of the nervous system	0.994	0.006	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.007	0.993
M06.34 Rheumatoid nodule (Hand)	0.000	0.008	0.992
E27.1 Primary adrenocortical insufficiency	0.992	0.008	0.000
G20-G26 Extrapyramidal and movement disorders	0.992	0.008	0.000
E10.3 With ophthalmic complications	0.000	0.008	0.992
# Top node	0.992	0.008	0.000
E05.9 Thyrotoxicosis, unspecified	0.991	0.009	0.000
D50-D53 Nutritional anaemias	0.990	0.010	0.000
E10.4 With neurological complications	0.000	0.013	0.987
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.000	0.014	0.986
D55-D59 Haemolytic anaemias	0.985	0.015	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.019	0.981
D51 Vitamin B12 deficiency anaemia	0.980	0.020	0.000
G20 Parkinson's disease	0.980	0.020	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.979	0.021	0.000
L20-L30 Dermatitis and eczema	0.977	0.023	0.000
D80-D89 Certain disorders involving the immune mechanism	0.977	0.023	0.000
D59 Acquired haemolytic anaemia	0.976	0.024	0.000
L27 Dermatitis due to substances taken internally	0.970	0.030	0.000
L27.0 Generalised skin eruption due to drugs and medicaments	0.965	0.035	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.000	0.036	0.964
D86 Sarcoidosis	0.964	0.036	0.000
M06.4 Inflammatory polyarthropathy	0.000	0.041	0.959
D59.1 Other autoimmune haemolytic anaemias	0.958	0.042	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.000	0.043	0.957
E22 Hyperfunction of pituitary gland	0.954	0.046	0.000
M45 Ankylosing spondylitis	0.000	0.048	0.952
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.950	0.050	0.000
L50-L54 Urticaria and erythema	0.948	0.052	0.000
K90 Intestinal malabsorption	0.946	0.054	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.000	0.061	0.939
M06.32 Rheumatoid nodule (Upper arm)	0.000	0.068	0.932
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.000	0.069	0.931
D68.0 Von Willebrand's disease	0.930	0.070	0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.926	0.074	0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.000	0.079	0.921
B37.8 Candidiasis of other sites	0.921	0.079	0.000
D52 Folate deficiency anaemia	0.920	0.080	0.000
Chapter I Certain infectious and parasitic diseases	0.919	0.081	0.000
D69 Purpura and other haemorrhagic conditions	0.919	0.081	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.915	0.085	0.000
E27.2 Addisonian crisis	0.910	0.090	0.000
B37 Candidiasis	0.910	0.090	0.000
B35-B49 Mycoses	0.909	0.091	0.000
G24 Dystonia	0.907	0.093	0.000
E22.0 Acromegaly and pituitary gigantism	0.907	0.093	0.000
E10.5 With peripheral circulatory complications	0.000	0.094	0.906
G37 Other demyelinating diseases of central nervous system	0.905	0.095	0.000
J33 Nasal polyp	0.000	0.096	0.904
E34 Other endocrine disorders	0.901	0.099	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.100	0.900
D68.6 Other Thrombophilia	0.900	0.100	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.899	0.101	0.000
D86.0 Sarcoidosis of lung	0.896	0.104	0.000
L21 Seborrhoeic dermatitis	0.892	0.108	0.000
L10-L14 Bullous disorders	0.889	0.111	0.000
G25 Other extrapyramidal and movement disorders	0.886	0.114	0.000
D86.3 Sarcoidosis of skin	0.879	0.121	0.000
D60-D64 Aplastic and other anaemias	0.879	0.121	0.000
L53 Other erythematous conditions	0.876	0.124	0.000
J33.0 Polyp of nasal cavity	0.000	0.127	0.873
E10.6 With other specified complications	0.000	0.129	0.871
D52.9 Folate deficiency anaemia, unspecified	0.870	0.130	0.000
D59.9 Acquired haemolytic anaemia, unspecified	0.869	0.131	0.000
D68.5 Primary Thrombophilia	0.867	0.133	0.000
D68.8 Other specified coagulation defects	0.867	0.133	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.865	0.135	0.000
L23 Allergic contact dermatitis	0.863	0.137	0.000
G24.9 Dystonia, unspecified	0.863	0.137	0.000
E28 Ovarian dysfunction	0.857	0.143	0.000
D86.9 Sarcoidosis, unspecified	0.855	0.145	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.000	0.145	0.855
D61 Other aplastic anaemias	0.853	0.147	0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.849	0.151	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.847	0.152	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.000	0.156	0.844
L13 Other bullous disorders	0.843	0.157	0.000
L52 Erythema nodosum	0.843	0.157	0.000
M14 Arthropathies in other diseases classified elsewhere	0.000	0.157	0.843
M06.30 Rheumatoid nodule (Multiple sites)	0.000	0.164	0.836
E20 Hypoparathyroidism	0.835	0.164	0.000
E40-E46 Malnutrition	0.832	0.167	0.001
D61.9 Aplastic anaemia, unspecified	0.832	0.168	0.000
L21.9 Seborrhoeic dermatitis, unspecified	0.830	0.170	0.000
K90.9 Intestinal malabsorption, unspecified	0.829	0.171	0.000
E10.0 With coma	0.000	0.172	0.828
B07 Viral warts	0.825	0.175	0.000
E10.1 With ketoacidosis	0.000	0.178	0.822
M05.8 Other seropositive rheumatoid arthritis	0.000	0.188	0.812
L13.0 Dermatitis herpetiformis	0.811	0.189	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.000	0.192	0.808
G25.8 Other specified extrapyramidal and movement disorders	0.804	0.196	0.000
D69.4 Other primary thrombocytopenia	0.804	0.196	0.000
M35.3 Polymyalgia rheumatica	0.000	0.197	0.803
D69.6 Thrombocytopenia, unspecified	0.801	0.199	0.000
G37.9 Demyelinating disease of central nervous system, unspecified	0.800	0.200	0.000
L53.9 Erythematous condition, unspecified	0.800	0.200	0.000
E34.0 Carcinoid syndrome	0.796	0.204	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.795	0.205	0.000
E04 Other non-toxic goitre	0.793	0.207	0.000
E31 Polyglandular dysfunction	0.792	0.208	0.000
E10.8 With unspecified complications	0.000	0.208	0.792
E21.0 Primary hyperparathyroidism	0.792	0.208	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.000	0.210	0.790
E03 Other hypothyroidism	0.282	0.212	0.506
E07 Other disorders of thyroid	0.783	0.214	0.002
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.785	0.215	0.000
E21.3 Hyperparathyroidism, unspecified	0.780	0.220	0.000
A80-A89 Viral infections of the central nervous system	0.775	0.225	0.000
M14.6 Neuropathic arthropathy	0.000	0.225	0.775
E22.9 Hyperfunction of pituitary gland, unspecified	0.774	0.226	0.000
L50 Urticaria	0.769	0.231	0.000
L25 Unspecified contact dermatitis	0.769	0.231	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.000	0.232	0.768
E04.0 Non-toxic diffuse goitre	0.767	0.232	0.000
G80-G83 Cerebral palsy and other paralytic syndromes	0.763	0.237	0.000
D68.1 Hereditary factor XI deficiency	0.760	0.240	0.000
B37.9 Candidiasis, unspecified	0.757	0.243	0.000
L27.1 Localised skin eruption due to drugs and medicaments	0.753	0.247	0.000
D69.8 Other specified haemorrhagic conditions	0.751	0.249	0.000
G37.8 Other specified demyelinating diseases of central nervous system	0.751	0.249	0.000
B25-B34 Other viral diseases	0.749	0.251	0.000
M06.8 Other specified rheumatoid arthritis	0.000	0.252	0.748
J33.1 Polypoid sinus degeneration	0.000	0.254	0.746
L53.0 Toxic erythema	0.745	0.255	0.000
L26 Exfoliative dermatitis	0.744	0.256	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.738	0.261	0.002
E27.9 Disorder of adrenal gland, unspecified	0.736	0.264	0.000
E07.8 Other specified disorders of thyroid	0.736	0.264	0.001
E34.8 Other specified endocrine disorders	0.733	0.267	0.000
A65-A69 Other spirochaetal diseases	0.732	0.268	0.000
G24.3 Spasmodic torticollis	0.731	0.269	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.727	0.273	0.000
M45.X2 Ankylosing spondylitis (Cervical region)	0.000	0.275	0.725
D66 Hereditary factor VIII deficiency	0.725	0.275	0.000
M12 Other specific arthropathies	0.000	0.276	0.724
D69.3 Idiopathic thrombocytopenic purpura	0.724	0.276	0.000
E27.8 Other specified disorders of adrenal gland	0.723	0.277	0.000
A50-A64 Infections with a predominantly sexual mode of transmission	0.721	0.279	0.000
L20 Atopic dermatitis	0.721	0.279	0.000
D59.0 Drug-induced autoimmune haemolytic anaemia	0.719	0.281	0.000
D68.2 Hereditary deficiency of other clotting factors	0.719	0.281	0.000
E20.9 Hypoparathyroidism, unspecified	0.719	0.281	0.000
D57 Sickle-cell disorders	0.718	0.281	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.000	0.283	0.717
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.283	0.717
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.000	0.283	0.717
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.000	0.283	0.717
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.283	0.717
M06.2 Rheumatoid bursitis	0.000	0.283	0.717
E05.5 Thyroid crisis or storm	0.717	0.283	0.000
E05.4 Thyrotoxicosis factitia	0.717	0.283	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.717	0.283	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.717	0.283	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.000	0.283	0.717
M05.1 Rheumatoid lung disease	0.000	0.283	0.717
M05.0 Felty's syndrome	0.000	0.283	0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.715	0.283	0.002
E00 Congenital iodine-deficiency syndrome	0.715	0.283	0.002
M09 Juvenile arthritis in diseases classified elsewhere	0.000	0.284	0.716
M06.39 Rheumatoid nodule (Site unspecified)	0.000	0.284	0.716
M06.38 Rheumatoid nodule (Other)	0.000	0.284	0.716
M06.36 Rheumatoid nodule (Lower leg)	0.000	0.284	0.716
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.000	0.284	0.716
M06.33 Rheumatoid nodule (Forearm)	0.000	0.284	0.716
M06.31 Rheumatoid nodule (Shoulder region)	0.000	0.284	0.716
L11 Other acantholytic disorders	0.716	0.284	0.000
B37.2 Candidiasis of skin and nail	0.716	0.284	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.000	0.284	0.716
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.000	0.284	0.716
M06.04 Seronegative rheumatoid arthritis (Hand)	0.000	0.284	0.716
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.000	0.284	0.716
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.000	0.284	0.716
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.000	0.284	0.716
E35 Disorders of endocrine glands in diseases classified elsewhere	0.716	0.284	0.000
E32 Diseases of thymus	0.716	0.284	0.000
E30 Disorders of puberty, not elsewhere classified	0.716	0.284	0.000
E21.2 Other hyperparathyroidism	0.715	0.285	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.715	0.285	0.000
E46 Unspecified protein-energy malnutrition	0.713	0.286	0.000
E27.5 Adrenomedullary hyperfunction	0.714	0.286	0.000
E27.0 Other adrenocortical overactivity	0.714	0.286	0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere	0.711	0.289	0.000
G22 Parkinsonism in diseases classified elsewhere	0.711	0.289	0.000
K90.8 Other intestinal malabsorption	0.710	0.290	0.000
E28.2 Polycystic ovarian syndrome	0.710	0.290	0.000
M45-M49 Spondylopathies	0.000	0.291	0.709
Chapter XVI Certain conditions originating in the perinatal period	0.709	0.291	0.000
D82 Immunodeficiency associated with other major defects	0.708	0.292	0.000
L23.5 Allergic contact dermatitis due to other chemical products	0.708	0.292	0.000
D61.0 Constitutional aplastic anaemia	0.707	0.293	0.000
B15-B19 Viral hepatitis	0.707	0.293	0.000
D55 Anaemia due to enzyme disorders	0.706	0.294	0.000
B25 Cytomegaloviral disease	0.704	0.296	0.000
D51.2 Transcobalamin II deficiency	0.703	0.297	0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.703	0.297	0.000
M05.2 Rheumatoid vasculitis	0.000	0.298	0.702
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.701	0.299	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.701	0.299	0.000
L24 Irritant contact dermatitis	0.700	0.299	0.000
L22 Diaper [napkin] dermatitis	0.700	0.299	0.000
D56 Thalassaemia	0.700	0.300	0.000
D81 Combined immunodeficiencies	0.700	0.300	0.000
D59.8 Other acquired haemolytic anaemias	0.700	0.300	0.000
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.700	0.300	0.000
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.700	0.300	0.000
D59.4 Other nonautoimmune haemolytic anaemias	0.700	0.300	0.000
D59.3 Haemolytic-uraemic syndrome	0.700	0.300	0.000
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.700	0.300	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.000	0.300	0.699
D86.1 Sarcoidosis of lymph nodes	0.696	0.304	0.000
L27.9 Dermatitis due to unspecified substance taken internally	0.695	0.304	0.000
L27.8 Dermatitis due to other substances taken internally	0.695	0.304	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.001	0.305	0.695
D68.4 Acquired coagulation factor deficiency	0.694	0.306	0.000
G24.1 Idiopathic familial dystonia	0.694	0.306	0.000
B37.1 Pulmonary candidiasis	0.692	0.308	0.000
D51.8 Other vitamin B12 deficiency anaemias	0.691	0.309	0.000
Chapter XXII Codes for special purposes	0.690	0.310	0.000
L23.1 Allergic contact dermatitis due to adhesives	0.689	0.310	0.000
E28.3 Primary ovarian failure	0.689	0.311	0.000
M08 Juvenile arthritis	0.000	0.312	0.688
M06.48 Inflammatory polyarthropathy (Other)	0.000	0.312	0.688
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.000	0.312	0.688
M06.46 Inflammatory polyarthropathy (Lower leg)	0.000	0.312	0.688
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.000	0.312	0.688
M06.44 Inflammatory polyarthropathy (Hand)	0.000	0.312	0.688
M06.43 Inflammatory polyarthropathy (Forearm)	0.000	0.312	0.688
M06.42 Inflammatory polyarthropathy (Upper arm)	0.000	0.312	0.688
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.000	0.312	0.688
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.686	0.313	0.000
D69.5 Secondary thrombocytopenia	0.686	0.314	0.000
E22.8 Other hyperfunction of pituitary gland	0.684	0.316	0.000
L50.1 Idiopathic urticaria	0.684	0.316	0.000
A20-A28 Certain zoonotic bacterial diseases	0.683	0.317	0.000
G23 Other degenerative diseases of basal ganglia	0.682	0.317	0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.000	0.317	0.682
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.000	0.317	0.682
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.000	0.317	0.682
M45.X4 Ankylosing spondylitis (Thoracic region)	0.000	0.317	0.682
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.000	0.317	0.682
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.000	0.317	0.682
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.000	0.318	0.682
G25.5 Other chorea	0.681	0.319	0.000
G81 Hemiplegia	0.681	0.319	0.000
L54 Erythema in diseases classified elsewhere	0.680	0.320	0.000
D68.9 Coagulation defect, unspecified	0.679	0.321	0.000
K90.3 Pancreatic steatorrhoea	0.678	0.322	0.000
K90.2 Blind loop syndrome, not elsewhere classified	0.678	0.322	0.000
K90.1 Tropical sprue	0.678	0.322	0.000
M35 Other systemic involvement of connective tissue	0.006	0.322	0.673
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)	0.000	0.323	0.677
G21 Secondary Parkinsonism	0.676	0.324	0.000
G00 Bacterial meningitis, not elsewhere classified	0.675	0.325	0.000
D51.3 Other dietary vitamin B12 deficiency anaemia	0.675	0.325	0.000
L23.9 Allergic contact dermatitis, unspecified cause	0.673	0.327	0.000
M11 Other crystal arthropathies	0.000	0.328	0.672
A86 Unspecified viral encephalitis	0.671	0.329	0.000
E10.7 With multiple complications	0.000	0.330	0.669
B01 Varicella [chickenpox]	0.669	0.330	0.000
G24.0 Drug-induced dystonia	0.667	0.333	0.000
G25.0 Essential tremor	0.665	0.335	0.000
M20-M25 Other joint disorders	0.000	0.337	0.663
D53 Other nutritional anaemias	0.663	0.337	0.000
D67 Hereditary factor IX deficiency	0.660	0.340	0.000
D52.8 Other folate deficiency anaemias	0.660	0.340	0.000
D52.1 Drug-induced folate deficiency anaemia	0.660	0.340	0.000
D52.0 Dietary folate deficiency anaemia	0.660	0.340	0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.659	0.341	0.000
A75-A79 Rickettsioses	0.659	0.341	0.000
A70-A74 Other diseases caused by chlamydiae	0.659	0.341	0.000
G25.1 Drug-induced tremor	0.658	0.342	0.000
B25.9 Cytomegaloviral disease, unspecified	0.658	0.342	0.000
M06.1 Adult-onset Still's disease	0.000	0.343	0.656
D89.1 Cryoglobulinaemia	0.656	0.344	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.653	0.347	0.000
B37.6 Candidal endocarditis	0.652	0.348	0.000
B37.5 Candidal meningitis	0.652	0.348	0.000
B48 Other mycoses, not elsewhere classified	0.652	0.348	0.000
B47 Mycetoma	0.652	0.348	0.000
B46 Zygomycosis	0.652	0.348	0.000
B45 Cryptococcosis	0.652	0.348	0.000
B43 Chromomycosis and phaeomycotic abscess	0.652	0.348	0.000
B42 Sporotrichosis	0.652	0.348	0.000
B41 Paracoccidioidomycosis	0.652	0.348	0.000
B40 Blastomycosis	0.652	0.348	0.000
B39 Histoplasmosis	0.652	0.348	0.000
B38 Coccidioidomycosis	0.652	0.348	0.000
G24.4 Idiopathic orofacial dystonia	0.651	0.349	0.000
G24.2 Idiopathic nonfamilial dystonia	0.651	0.349	0.000
D69.1 Qualitative platelet defects	0.650	0.350	0.000
L30 Other dermatitis	0.650	0.350	0.000
G37.5 Concentric sclerosis [Balo]	0.649	0.351	0.000
G37.4 Subacute necrotising myelitis	0.649	0.351	0.000
G37.2 Central pontine myelinolysis	0.649	0.351	0.000
G37.1 Central demyelination of corpus callosum	0.649	0.351	0.000
G37.0 Diffuse sclerosis	0.649	0.351	0.000
B20-B24 Human immunodeficiency virus [HIV] disease	0.646	0.354	0.000
B65-B83 Helminthiases	0.646	0.354	0.000
E34.5 Androgen resistance syndrome	0.646	0.354	0.000
E34.4 Constitutional tall stature	0.646	0.354	0.000
E34.3 Short stature, not elsewhere classified	0.646	0.354	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.646	0.354	0.000
E34.1 Other hypersecretion of intestinal hormones	0.646	0.354	0.000
J33.8 Other polyp of sinus	0.000	0.354	0.646
B37.7 Candidal septicaemia	0.645	0.355	0.000
E21.4 Other specified disorders of parathyroid gland	0.645	0.355	0.000
E31.0 Autoimmune polyglandular failure	0.645	0.355	0.000
D64 Other anaemias	0.644	0.356	0.000
E34.9 Endocrine disorder, unspecified	0.642	0.358	0.000
G36 Other acute disseminated demyelination	0.642	0.358	0.000
B00 Herpesviral [herpes simplex] infections	0.640	0.360	0.000
L21.8 Other seborrhoeic dermatitis	0.639	0.361	0.000
L21.1 Seborrhoeic infantile dermatitis	0.639	0.361	0.000
L21.0 Seborrhoea capitis	0.639	0.361	0.000
D86.8 Sarcoidosis of other and combined sites	0.639	0.361	0.000
D58 Other hereditary haemolytic anaemias	0.638	0.361	0.000
L51 Erythema multiforme	0.638	0.361	0.000
L14 Bullous disorders in diseases classified elsewhere	0.637	0.362	0.000
M30 Polyarteritis nodosa and related conditions	0.000	0.362	0.637
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.637	0.363	0.000
B36 Other superficial mycoses	0.635	0.364	0.000
G25.6 Drug-induced tics and other tics of organic origin	0.635	0.364	0.000
G25.4 Drug-induced chorea	0.635	0.364	0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.635	0.365	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.634	0.366	0.000
B90-B94 Sequelae of infectious and parasitic diseases	0.633	0.367	0.000
E10-E14 Diabetes mellitus	0.040	0.368	0.593
L23.3 Allergic contact dermatitis due to drugs in contact with the skin	0.631	0.368	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.630	0.370	0.000
G25.2 Other specified forms of tremor	0.629	0.370	0.000
E10.2 With renal complications	0.000	0.371	0.629
B85-B89 Pediculosis, acariasis and other infestations	0.629	0.371	0.000
D69.2 Other nonthrombocytopenic purpura	0.628	0.372	0.000
L27.2 Dermatitis due to ingested food	0.628	0.372	0.000
L53.3 Other chronic figurate erythema	0.628	0.372	0.000
L53.2 Erythema marginatum	0.628	0.372	0.000
L53.1 Erythema annulare centrifugum	0.628	0.372	0.000
G25.9 Extrapyramidal and movement disorder, unspecified	0.627	0.372	0.000
D83 Common variable immunodeficiency	0.627	0.373	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.626	0.374	0.000
M20 Acquired deformities of fingers and toes	0.000	0.376	0.624
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.623	0.377	0.000
L28 Lichen simplex chronicus and prurigo	0.621	0.379	0.000
G00.9 Bacterial meningitis, unspecified	0.621	0.379	0.000
D89.3 Immune reconstitution syndrome	0.620	0.380	0.000
L25.9 Unspecified contact dermatitis, unspecified cause	0.619	0.381	0.000
L23.8 Allergic contact dermatitis due to other agents	0.619	0.381	0.000
L23.7 Allergic contact dermatitis due to plants, except food	0.619	0.381	0.000
L23.6 Allergic contact dermatitis due to food in contact with the skin	0.619	0.381	0.000
L23.4 Allergic contact dermatitis due to dyes	0.619	0.381	0.000
L23.2 Allergic contact dermatitis due to cosmetics	0.619	0.381	0.000
L23.0 Allergic contact dermatitis due to metals	0.619	0.381	0.000
E50-E64 Other nutritional deficiencies	0.616	0.383	0.001
L50.0 Allergic urticaria	0.615	0.385	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.615	0.385	0.000
E28.9 Ovarian dysfunction, unspecified	0.614	0.386	0.000
E28.8 Other ovarian dysfunction	0.614	0.386	0.000
E28.1 Androgen excess	0.614	0.386	0.000
E28.0 Oestrogen excess	0.614	0.386	0.000
G81.9 Hemiplegia, unspecified	0.613	0.387	0.000
A63 Other predominantly sexually transmitted diseases, not elsewhere classified	0.612	0.388	0.000
M20.6 Acquired deformity of toe(s), unspecified	0.000	0.388	0.612
D61.8 Other specified aplastic anaemias	0.611	0.388	0.000
D61.3 Idiopathic aplastic anaemia	0.611	0.388	0.000
D61.2 Aplastic anaemia due to other external agents	0.611	0.388	0.000
G30-G32 Other degenerative diseases of the nervous system	0.611	0.389	0.000
B50-B64 Protozoal diseases	0.610	0.390	0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis	0.609	0.391	0.000
B06 Rubella [German measles]	0.609	0.391	0.000
B05 Measles	0.609	0.391	0.000
B09 Unspecified viral infection characterised by skin and mucous membrane lesions	0.609	0.391	0.000
B04 Monkeypox	0.609	0.391	0.000
B03 Smallpox	0.609	0.391	0.000
I64 Stroke, not specified as haemorrhage or infarction	0.607	0.393	0.000
L13.9 Bullous disorder, unspecified	0.605	0.395	0.000
L13.8 Other specified bullous disorders	0.605	0.395	0.000
L13.1 Subcorneal pustular dermatitis	0.605	0.395	0.000
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders	0.000	0.395	0.604
M14.4 Arthropathy in amyloidosis	0.000	0.395	0.604
M14.3 Lipoid dermatoarthritis	0.000	0.395	0.604
M14.1 Crystal arthropathy in other metabolic disorders	0.000	0.395	0.604
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders	0.000	0.395	0.604
D84 Other immunodeficiencies	0.604	0.396	0.000
L10 Pemphigus	0.601	0.398	0.000
A80 Acute poliomyelitis	0.601	0.399	0.000
E20.8 Other hypoparathyroidism	0.599	0.401	0.000
E20.1 Pseudohypoparathyroidism	0.599	0.401	0.000
E20.0 Idiopathic hypoparathyroidism	0.599	0.401	0.000
A69 Other spirochaetal infections	0.598	0.402	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.596	0.403	0.001
E45 Retarded development following protein-energy malnutrition	0.596	0.403	0.001
E43 Unspecified severe protein-energy malnutrition	0.596	0.403	0.001
E42 Marasmic kwashiorkor	0.596	0.403	0.001
E41 Nutritional marasmus	0.596	0.403	0.001
E40 Kwashiorkor	0.596	0.403	0.001
E25 Adrenogenital disorders	0.596	0.403	0.000
B17 Other acute viral hepatitis	0.596	0.404	0.000
D64.8 Other specified anaemias	0.595	0.405	0.000
D69.0 Allergic purpura	0.595	0.405	0.000
L30.8 Other specified dermatitis	0.595	0.405	0.000
L11.0 Acquired keratosis follicularis	0.594	0.406	0.000
B19 Unspecified viral hepatitis	0.592	0.408	0.000
B37.4 Candidiasis of other urogenital sites	0.589	0.410	0.000
M45.X6 Ankylosing spondylitis (Lumbar region)	0.000	0.412	0.587
M14.2 Diabetic arthropathy	0.000	0.415	0.585
M91-M94 Chondropathies	0.000	0.416	0.584
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.000	0.416	0.584
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)	0.000	0.418	0.582
M05.88 Other seropositive rheumatoid arthritis (Other)	0.000	0.418	0.582
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)	0.000	0.418	0.582
M05.86 Other seropositive rheumatoid arthritis (Lower leg)	0.000	0.418	0.582
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)	0.000	0.418	0.582
M05.84 Other seropositive rheumatoid arthritis (Hand)	0.000	0.418	0.582
M05.83 Other seropositive rheumatoid arthritis (Forearm)	0.000	0.418	0.582
M05.82 Other seropositive rheumatoid arthritis (Upper arm)	0.000	0.418	0.582
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)	0.000	0.418	0.582
I60-I69 Cerebrovascular diseases	0.580	0.420	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.579	0.421	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.578	0.421	0.000
B49 Unspecified mycosis	0.576	0.424	0.000
A81 Atypical virus infections of central nervous system	0.576	0.424	0.000
M30.0 Polyarteritis nodosa	0.000	0.424	0.576
I63 Cerebral infarction	0.574	0.426	0.000
Chapter IX Diseases of the circulatory system	0.574	0.426	0.000
E29 Testicular dysfunction	0.571	0.429	0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.570	0.430	0.000
G24.8 Other dystonia	0.569	0.431	0.000
E04.8 Other specified non-toxic goitre	0.568	0.431	0.000
E31.9 Polyglandular dysfunction, unspecified	0.568	0.432	0.000
E31.8 Other polyglandular dysfunction	0.568	0.432	0.000
E31.1 Polyglandular hyperfunction	0.568	0.432	0.000
A15-A19 Tuberculosis	0.566	0.434	0.000
E03.5 Myxoedema coma	0.202	0.435	0.363
E03.4 Atrophy of thyroid (acquired)	0.202	0.435	0.363
E03.3 Postinfectious hypothyroidism	0.202	0.435	0.363
E03.0 Congenital hypothyroidism with diffuse goitre	0.184	0.436	0.380
E07.1 Dyshormogenetic goitre	0.562	0.437	0.002
E07.0 Hypersecretion of calcitonin	0.562	0.437	0.002
E04.2 Non-toxic multinodular goitre	0.562	0.438	0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.000	0.439	0.561
L50.8 Other urticaria	0.559	0.440	0.000
B25.0 Cytomegaloviral pneumonitis	0.559	0.441	0.000
M20.4 Other hammer toe(s) (acquired)	0.000	0.442	0.558
L20.9 Atopic dermatitis, unspecified	0.557	0.443	0.000
D62 Acute posthaemorrhagic anaemia	0.556	0.444	0.000
A88 Other viral infections of central nervous system, not elsewhere classified	0.556	0.444	0.000
A85 Other viral encephalitis, not elsewhere classified	0.556	0.444	0.000
A84 Tick-borne viral encephalitis	0.556	0.444	0.000
A83 Mosquito-borne viral encephalitis	0.556	0.444	0.000
A82 Rabies	0.556	0.444	0.000
A91 Dengue haemorrhagic fever	0.556	0.444	0.000
A90 Dengue fever [classical dengue]	0.556	0.444	0.000
A89 Unspecified viral infection of central nervous system	0.556	0.444	0.000
G25.3 Myoclonus	0.554	0.446	0.000
E13 Other specified diabetes mellitus	0.016	0.447	0.537
L53.8 Other specified erythematous conditions	0.552	0.448	0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.552	0.448	0.000
L50.6 Contact urticaria	0.551	0.449	0.000
L50.5 Cholinergic urticaria	0.551	0.449	0.000
L50.4 Vibratory urticaria	0.551	0.449	0.000
L50.3 Dermatographic urticaria	0.551	0.449	0.000
L50.2 Urticaria due to cold and heat	0.551	0.449	0.000
L25.8 Unspecified contact dermatitis due to other agents	0.551	0.449	0.000
L25.5 Unspecified contact dermatitis due to plants, except food	0.551	0.449	0.000
L25.4 Unspecified contact dermatitis due to food in contact with the skin	0.551	0.449	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations