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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs9269081
log Bayes Factor = 250.357
Chromosome 6   position 32,441,100  (GRCh37) Explore rs9269081 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
J33.9 Nasal polyp, unspecified
0.000 0.000 1.000
K51.9 Ulcerative colitis, unspecified
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
J33 Nasal polyp
0.000 0.000 1.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
J40-J47 Chronic lower respiratory diseases
0.000 0.000 1.000
J30-J39 Other diseases of upper respiratory tract
0.000 0.000 1.000
M05-M14 Inflammatory polyarthropathies
0.000 0.000 1.000
Chapter X Diseases of the respiratory system
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
# Top node
0.000 0.000 1.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E16.2 Hypoglycaemia, unspecified
0.000 0.000 1.000
J45.9 Asthma, unspecified
0.000 0.000 1.000
J32 Chronic sinusitis
0.000 0.000 1.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.000 1.000
M05 Seropositive rheumatoid arthritis
0.000 0.000 1.000
E16 Other disorders of pancreatic internal secretion
0.000 0.000 1.000
E10.4 With neurological complications
0.000 0.000 1.000
J33.0 Polyp of nasal cavity
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.000 1.000
E14.9 Without complications
0.000 0.000 1.000
J45 Asthma
0.000 0.000 1.000
J44 Other chronic obstructive pulmonary disease
0.000 0.000 1.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.000 0.000 1.000
Chapter XI Diseases of the digestive system
0.000 0.000 1.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.000 1.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.000 1.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
J32.9 Chronic sinusitis, unspecified
0.000 0.000 1.000
J33.8 Other polyp of sinus
0.000 0.000 1.000
H36.0 Diabetic retinopathy
0.000 0.000 1.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.000 0.001 0.999
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.001 0.999
C83.3 Large cell (diffuse)
0.000 0.001 0.999
C83 Diffuse non-Hodgkin's lymphoma
0.000 0.001 0.999
K90 Intestinal malabsorption
0.000 0.001 0.999
K70-K77 Diseases of liver
0.000 0.002 0.998
K90-K93 Other diseases of the digestive system
0.000 0.002 0.998
M20-M25 Other joint disorders
0.000 0.002 0.998
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.002 0.998
K51 Ulcerative colitis
0.997 0.003 0.000
M25.4 Effusion of joint
0.000 0.005 0.995
M25.46 Effusion of joint (Lower leg)
0.000 0.005 0.995
M25 Other joint disorders, not elsewhere classified
0.000 0.005 0.995
M35 Other systemic involvement of connective tissue
0.000 0.006 0.994
M35.3 Polymyalgia rheumatica
0.000 0.006 0.994
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.006 0.994
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.007 0.993
M06.0 Seronegative rheumatoid arthritis
0.000 0.007 0.993
E14.3 With ophthalmic complications
0.000 0.007 0.993
E78.0 Pure hypercholesterolaemia
0.000 0.008 0.992
E78.5 Hyperlipidaemia, unspecified
0.000 0.008 0.992
E10.5 With peripheral circulatory complications
0.000 0.010 0.990
E70-E90 Metabolic disorders
0.000 0.012 0.988
K74 Fibrosis and cirrhosis of liver
0.000 0.012 0.988
E11.1 With ketoacidosis
0.000 0.013 0.987
J46 Status asthmaticus
0.000 0.016 0.984
Chapter II Neoplasms
0.000 0.017 0.983
K74.3 Primary biliary cirrhosis
0.000 0.018 0.982
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.000 0.019 0.981
M31 Other necrotising vasculopathies
0.000 0.021 0.979
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.000 0.022 0.978
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.023 0.977
E10.2 With renal complications
0.000 0.026 0.974
M31.6 Other giant cell arteritis
0.000 0.028 0.972
G35-G37 Demyelinating diseases of the central nervous system
0.971 0.029 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.971 0.029 0.000
M06.3 Rheumatoid nodule
0.000 0.029 0.971
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.000 0.029 0.971
Chapter VIII Diseases of the ear and mastoid process
0.000 0.031 0.969
K76 Other diseases of liver
0.000 0.032 0.968
K76.8 Other specified diseases of liver
0.000 0.033 0.967
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.034 0.966
G37 Other demyelinating diseases of central nervous system
0.965 0.035 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.000 0.039 0.961
J86 Pyothorax
0.000 0.041 0.959
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.044 0.956
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.045 0.955
K55-K64 Other diseases of intestines
0.000 0.045 0.955
K60 Fissure and fistula of anal and rectal regions
0.000 0.046 0.954
G37.9 Demyelinating disease of central nervous system, unspecified
0.952 0.048 0.000
D86.0 Sarcoidosis of lung
0.951 0.049 0.000
M65-M68 Disorders of synovium and tendon
0.000 0.051 0.949
D86 Sarcoidosis
0.946 0.054 0.000
H60-H62 Diseases of external ear
0.000 0.056 0.944
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.057 0.943
E11.5 With peripheral circulatory complications
0.000 0.064 0.936
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.000 0.064 0.936
J32.4 Chronic pansinusitis
0.000 0.066 0.934
J43 Emphysema
0.000 0.067 0.933
M65 Synovitis and tenosynovitis
0.000 0.068 0.932
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.068 0.932
K51.8 Other ulcerative colitis
0.929 0.071 0.000
K50-K52 Noninfective enteritis and colitis
0.019 0.072 0.909
K51.2 Ulcerative (chronic) proctitis
0.928 0.072 0.000
D86.9 Sarcoidosis, unspecified
0.926 0.074 0.000
K58 Irritable bowel syndrome
0.000 0.075 0.925
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.000 0.076 0.924
K58.0 Irritable bowel syndrome with diarrhoea
0.000 0.081 0.919
K60.2 Anal fissure, unspecified
0.000 0.084 0.916
H90-H95 Other disorders of ear
0.000 0.084 0.916
J86.9 Pyothorax without fistula
0.000 0.085 0.915
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.085 0.915
H61 Other disorders of external ear
0.000 0.088 0.912
M06.34 Rheumatoid nodule (Hand)
0.000 0.091 0.909
H91 Other hearing loss
0.000 0.091 0.909
K60.0 Acute anal fissure
0.000 0.091 0.909
H91.9 Hearing loss, unspecified
0.000 0.096 0.904
C09 Malignant neoplasm of tonsil
0.000 0.098 0.902
C02.1 Border of tongue
0.000 0.101 0.899
E10.6 With other specified complications
0.000 0.102 0.898
J44.9 Chronic obstructive pulmonary disease, unspecified
0.000 0.104 0.896
K50 Crohn's disease [regional enteritis]
0.001 0.106 0.893
E10.0 With coma
0.000 0.111 0.889
J32.8 Other chronic sinusitis
0.000 0.112 0.888
M65.9 Synovitis and tenosynovitis, unspecified
0.000 0.117 0.883
H36 Retinal disorders in diseases classified elsewhere
0.000 0.118 0.882
M65.4 Radial styloid tenosynovitis [de Quervain]
0.000 0.118 0.882
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.118 0.882
C82.2 Large cell, follicular
0.000 0.118 0.881
E40-E46 Malnutrition
0.000 0.122 0.878
M25.47 Effusion of joint (Ankle and foot)
0.000 0.123 0.877
J86.0 Pyothorax with fistula
0.000 0.125 0.875
H61.0 Perichondritis of external ear
0.000 0.126 0.874
L43.9 Lichen planus, unspecified
0.000 0.128 0.872
E11.3 With ophthalmic complications
0.000 0.129 0.871
M25.6 Stiffness of joint, not elsewhere classified
0.000 0.129 0.871
L43 Lichen planus
0.000 0.130 0.870
C02.9 Tongue, unspecified
0.000 0.132 0.868
K50.8 Other Crohn's disease
0.000 0.132 0.868
L40-L45 Papulosquamous disorders
0.000 0.132 0.868
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.137 0.863
C09.9 Tonsil, unspecified
0.000 0.137 0.863
K73 Chronic hepatitis, not elsewhere classified
0.000 0.140 0.860
E13 Other specified diabetes mellitus
0.000 0.142 0.858
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)
0.000 0.143 0.857
D86.1 Sarcoidosis of lymph nodes
0.855 0.145 0.000
J43.9 Emphysema, unspecified
0.000 0.149 0.851
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.151 0.848
J37 Chronic laryngitis and laryngotracheitis
0.000 0.158 0.841
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.000 0.161 0.839
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.000 0.163 0.837
K72 Hepatic failure, not elsewhere classified
0.000 0.170 0.830
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.830 0.170 0.000
E14.8 With unspecified complications
0.000 0.177 0.823
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.178 0.822
K74.5 Biliary cirrhosis, unspecified
0.000 0.178 0.822
M25.40 Effusion of joint (Multiple sites)
0.000 0.183 0.817
M06.4 Inflammatory polyarthropathy
0.000 0.186 0.814
E11.8 With unspecified complications
0.000 0.188 0.812
C82.0 Small cleaved cell, follicular
0.000 0.188 0.812
E06 Thyroiditis
0.000 0.189 0.811
J32.1 Chronic frontal sinusitis
0.000 0.191 0.809
D80-D89 Certain disorders involving the immune mechanism
0.787 0.191 0.021
E89.2 Postprocedural hypoparathyroidism
0.000 0.193 0.807
H61.1 Non-infective disorders of pinna
0.000 0.199 0.801
J32.2 Chronic ethmoidal sinusitis
0.000 0.200 0.800
E14.5 With peripheral circulatory complications
0.000 0.200 0.800
H30-H36 Disorders of choroid and retina
0.000 0.202 0.798
E89.3 Postprocedural hypopituitarism
0.000 0.203 0.797
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)
0.000 0.204 0.796
H60 Otitis externa
0.000 0.204 0.796
C12 Malignant neoplasm of pyriform sinus
0.000 0.205 0.795
H40.9 Glaucoma, unspecified
0.000 0.206 0.794
K60.5 Anorectal fistula
0.000 0.206 0.794
Chapter VII Diseases of the eye and adnexa
0.000 0.206 0.794
E46 Unspecified protein-energy malnutrition
0.000 0.210 0.790
E11.0 With coma
0.000 0.211 0.789
J33.1 Polypoid sinus degeneration
0.000 0.213 0.787
C11 Malignant neoplasm of nasopharynx
0.000 0.213 0.787
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.215 0.785
H40-H42 Glaucoma
0.000 0.217 0.783
G37.8 Other specified demyelinating diseases of central nervous system
0.783 0.217 0.000
J95-J99 Other diseases of the respiratory system
0.000 0.217 0.783
L40 Psoriasis
0.000 0.217 0.783
E78.2 Mixed hyperlipidaemia
0.000 0.218 0.782
E78.6 Lipoprotein deficiency
0.000 0.218 0.781
M35.1 Other overlap syndromes
0.000 0.220 0.780
J43.2 Centrilobular emphysema
0.000 0.222 0.778
K75 Other inflammatory liver diseases
0.000 0.222 0.778
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)
0.000 0.223 0.777
H40 Glaucoma
0.000 0.224 0.776
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)
0.000 0.225 0.775
E16.1 Other hypoglycaemia
0.000 0.226 0.774
C10 Malignant neoplasm of oropharynx
0.000 0.226 0.774
K60.3 Anal fistula
0.000 0.228 0.772
K50.1 Crohn's disease of large intestine
0.000 0.230 0.769
C91 Lymphoid leukaemia
0.000 0.232 0.768
C02.4 Lingual tonsil
0.000 0.233 0.767
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.236 0.764
C06 Malignant neoplasm of other and unspecified parts of mouth
0.000 0.236 0.764
C01 Malignant neoplasm of base of tongue
0.000 0.238 0.762
J41 Simple and mucopurulent chronic bronchitis
0.000 0.239 0.761
C82.3 Follicular lymphoma grade IIIa
0.000 0.240 0.760
K57 Diverticular disease of intestine
0.000 0.241 0.759
C85.1 B-cell lymphoma, unspecified
0.000 0.242 0.758
C07 Malignant neoplasm of parotid gland
0.000 0.242 0.758
E13.9 Without complications
0.000 0.243 0.757
K57.3 Diverticular disease of large intestine without perforation or abscess
0.000 0.247 0.753
K51.4 Pseudopolyposis of colon
0.752 0.248 0.000
M34 Systemic sclerosis
0.000 0.248 0.752
M60-M63 Disorders of muscles
0.000 0.249 0.751
H91.1 Presbycusis
0.000 0.251 0.749
K51.5 Mucosal proctocolitis
0.749 0.251 0.000
C83.1 Small cleaved cell (diffuse)
0.000 0.252 0.748
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.740 0.252 0.008
L40.5 Arthropathic psoriasis
0.000 0.253 0.747
M65.8 Other synovitis and tenosynovitis
0.000 0.253 0.747
C04 Malignant neoplasm of floor of mouth
0.000 0.254 0.746
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.000 0.257 0.743
C84 Peripheral and cutaneous T-cell lymphomas
0.000 0.259 0.741
K60.4 Rectal fistula
0.000 0.260 0.740
E06.3 Autoimmune thyroiditis
0.000 0.260 0.740
K60.1 Chronic anal fissure
0.000 0.260 0.740
J31.2 Chronic pharyngitis
0.000 0.262 0.738
M25.68 Stiffness of joint, not elsewhere classified (Other)
0.000 0.264 0.736
H61.8 Other specified disorders of external ear
0.000 0.267 0.733
J85 Abscess of lung and mediastinum
0.000 0.269 0.731
M31.9 Necrotising vasculopathy, unspecified
0.000 0.269 0.730
M65.94 Synovitis and tenosynovitis, unspecified (Hand)
0.000 0.270 0.730
M25.41 Effusion of joint (Shoulder region)
0.000 0.270 0.730
J37.0 Chronic laryngitis
0.000 0.272 0.728
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.728 0.272 0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.273 0.727
C03 Malignant neoplasm of gum
0.000 0.274 0.726
E50-E64 Other nutritional deficiencies
0.000 0.275 0.725
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.000 0.279 0.721
J32.3 Chronic sphenoidal sinusitis
0.000 0.282 0.718
C15-C26 Malignant neoplasms of digestive organs
0.000 0.282 0.718
M25.42 Effusion of joint (Upper arm)
0.000 0.283 0.717
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.283 0.717
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.283 0.717
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.283 0.717
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.283 0.717
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.283 0.717
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.283 0.717
E10.8 With unspecified complications
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.6 With other specified complications
0.000 0.283 0.717
E14.2 Withrenal complications
0.000 0.283 0.717
E14.1 With ketoacidosis
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.717
M08 Juvenile arthritis
0.000 0.283 0.717
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.283 0.717
M05.8 Other seropositive rheumatoid arthritis
0.000 0.283 0.717
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.283 0.717
M05.1 Rheumatoid lung disease
0.000 0.283 0.717
M05.0 Felty's syndrome
0.000 0.283 0.717
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.283 0.717
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.283 0.717
E16.4 Abnormal secretion of gastrin
0.000 0.283 0.717
E16.3 Increased secretion of glucagon
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.717
C82.6 Cutaneous follicle centre lymphoma
0.000 0.283 0.717
C82.5 Diffuse follicle centre lymphoma
0.000 0.283 0.717
C82.4 Follicular lymphoma grade IIIb
0.000 0.283 0.717
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.000 0.283 0.717
C94 Other leukaemias of specified cell type
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
H91.8 Other specified hearing loss
0.000 0.284 0.716
C83.6 Undifferentiated (diffuse)
0.000 0.284 0.716
C83.5 Lymphoblastic (diffuse)
0.000 0.284 0.716
C83.4 Immunoblastic (diffuse)
0.000 0.284 0.716
C83.2 Mixed small and large cell (diffuse)
0.000 0.284 0.716
L43.8 Other lichen planus
0.000 0.284 0.716
K90.3 Pancreatic steatorrhoea
0.000 0.284 0.716
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.284 0.716
K90.1 Tropical sprue
0.000 0.284 0.716
K77 Liver disorders in diseases classified elsewhere
0.000 0.284 0.716
K50.9 Crohn's disease, unspecified
0.000 0.284 0.716
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.284 0.716
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.000 0.284 0.716
D86.8 Sarcoidosis of other and combined sites
0.715 0.285 0.000
M25.49 Effusion of joint (Site unspecified)
0.000 0.286 0.713
M25.48 Effusion of joint (Other)
0.000 0.286 0.713
M25.2 Flail joint
0.000 0.287 0.713
M25.1 Fistula of joint
0.000 0.287 0.713
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.287 0.713
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.287 0.713
M35.5 Multifocal fibrosclerosis
0.000 0.287 0.713
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.287 0.713
E78.3 Hyperchylomicronaemia
0.000 0.288 0.712
E89.0 Postprocedural hypothyroidism
0.000 0.288 0.712
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.288 0.712
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.288 0.712
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.288 0.712
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.288 0.712
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.288 0.712
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.288 0.712
M25.0 Haemarthrosis
0.000 0.289 0.711
M14 Arthropathies in other diseases classified elsewhere
0.000 0.291 0.709
E77 Disorders of glycoprotein metabolism
0.000 0.291 0.708
E76 Disorders of glycosaminoglycan metabolism
0.000 0.291 0.708
E72 Other disorders of amino-acid metabolism
0.000 0.291 0.708
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.291 0.708
E70 Disorders of aromatic amino-acid metabolism
0.000 0.291 0.708
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.291 0.708
K74.4 Secondary biliary cirrhosis
0.000 0.292 0.708
K74.2 Hepatic fibrosis with hepatic sclerosis
0.000 0.292 0.708
K74.1 Hepatic sclerosis
0.000 0.292 0.708
K90.9 Intestinal malabsorption, unspecified
0.000 0.292 0.708
K73.9 Chronic hepatitis, unspecified
0.000 0.293 0.707
H61.3 Acquired stenosis of external ear canal
0.000 0.294 0.706
J45.1 Nonallergic asthma
0.000 0.295 0.705
C83.7 Burkitt's tumour
0.000 0.295 0.705
E14.4 With neurological complications
0.000 0.295 0.705
K51.1 Ulcerative (chronic) ileocolitis
0.704 0.295 0.000
C13 Malignant neoplasm of hypopharynx
0.000 0.296 0.704
E03.1 Congenital hypothyroidism without goitre
0.000 0.297 0.703
M35.7 Hypermobility syndrome
0.000 0.297 0.703
M31.8 Other specified necrotising vasculopathies
0.000 0.298 0.702
M31.7 Microscopic polyangiitis
0.000 0.298 0.702
M31.4 Aortic arch syndrome [Takayasu]
0.000 0.298 0.702
M31.2 Lethal midline granuloma
0.000 0.298 0.702
M25.43 Effusion of joint (Forearm)
0.000 0.298 0.702
C85.0 Lymphosarcoma
0.000 0.299 0.701
K75.4 Autoimmune hepatitis
0.000 0.300 0.700
D89.2 Hypergammaglobulinaemia, unspecified
0.699 0.300 0.001
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.301 0.699
E03.8 Other specified hypothyroidism
0.000 0.303 0.697
M06.8 Other specified rheumatoid arthritis
0.000 0.303 0.697
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.304 0.696
M06.38 Rheumatoid nodule (Other)
0.000 0.304 0.696
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.304 0.696
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.304 0.696
M06.33 Rheumatoid nodule (Forearm)
0.000 0.304 0.696
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.304 0.696
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.304 0.696
G36 Other acute disseminated demyelination
0.696 0.304 0.000
K76.5 Hepatic veno-occlusive disease
0.000 0.306 0.694
K76.4 Peliosis hepatis
0.000 0.306 0.694
K76.3 Infarction of liver
0.000 0.306 0.694
K76.2 Central haemorrhagic necrosis of liver
0.000 0.306 0.694
C21 Malignant neoplasm of anus and anal canal
0.000 0.307 0.693
M65.86 Other synovitis and tenosynovitis (Lower leg)
0.000 0.308 0.692
M25.8 Other specified joint disorders
0.000 0.308 0.692
M30 Polyarteritis nodosa and related conditions
0.000 0.308 0.692
G37.5 Concentric sclerosis [Balo]
0.692 0.308 0.000
G37.4 Subacute necrotising myelitis
0.692 0.308 0.000
G37.2 Central pontine myelinolysis
0.692 0.308 0.000
G37.1 Central demyelination of corpus callosum
0.692 0.308 0.000
G37.0 Diffuse sclerosis
0.692 0.308 0.000
M65.1 Other infective (teno)synovitis
0.000 0.310 0.689
C95 Leukaemia of unspecified cell type
0.000 0.311 0.689
C02.8 Overlapping lesion of tongue
0.000 0.311 0.689
C02.3 Anterior two-thirds of tongue, part unspecified
0.000 0.311 0.689
C02.2 Ventral surface of tongue
0.000 0.311 0.689
C02.0 Dorsal surface of tongue
0.000 0.311 0.689
M25.64 Stiffness of joint, not elsewhere classified (Hand)
0.000 0.314 0.686
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.315 0.685
K64 Haemorrhoids and perianal venous thrombosis
0.000 0.315 0.685
E11.6 With other specified complications
0.000 0.317 0.683
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)
0.000 0.317 0.683
C45 Mesothelioma
0.000 0.318 0.682
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.000 0.319 0.680
M60 Myositis
0.000 0.320 0.680
J32.0 Chronic maxillary sinusitis
0.000 0.320 0.680
K72.9 Hepatic failure, unspecified
0.000 0.321 0.679
M05.2 Rheumatoid vasculitis
0.000 0.323 0.677
H62 Disorders of external ear in diseases classified elsewhere
0.000 0.323 0.677
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.325 0.675
J45.8 Mixed asthma
0.000 0.325 0.675
E74 Other disorders of carbohydrate metabolism
0.000 0.326 0.674
E11.2 With renal complications
0.000 0.326 0.674
E78.1 Pure hyperglyceridaemia
0.000 0.327 0.673
C91.1 Chronic lymphocytic leukaemia
0.000 0.327 0.673
H60.4 Cholesteatoma of external ear
0.000 0.328 0.672
K76.7 Hepatorenal syndrome
0.000 0.329 0.671
J43.8 Other emphysema
0.000 0.330 0.670
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.330 0.670
J43.1 Panlobular emphysema
0.000 0.331 0.669
J43.0 MacLeod's syndrome
0.000 0.331 0.669
M65.2 Calcific tendinitis
0.000 0.331 0.668
M65.0 Abscess of tendon sheath
0.000 0.331 0.668
H92 Otalgia and effusion of ear
0.000 0.332 0.668
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.332 0.668
C05 Malignant neoplasm of palate
0.000 0.333 0.667
L40.9 Psoriasis, unspecified
0.000 0.335 0.665
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.000 0.335 0.665
C08 Malignant neoplasm of other and unspecified major salivary glands
0.000 0.336 0.664
L00-L08 Infections of the skin and subcutaneous tissue
0.000 0.337 0.663
H60.3 Other infective otitis externa
0.000 0.337 0.663
H34 Retinal vascular occlusions
0.000 0.337 0.663
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.000 0.340 0.659
H94 Other disorders of ear in diseases classified elsewhere
0.000 0.343 0.657
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.344 0.656
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.344 0.656
E89.5 Postprocedural testicular hypofunction
0.000 0.344 0.656
E89.1 Postprocedural hypoinsulinaemia
0.000 0.344 0.656
C21.0 Anus, unspecified
0.000 0.345 0.655
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.346 0.654
M07 Psoriatic and enteropathic arthropathies
0.000 0.346 0.654
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.347 0.653
J35 Chronic diseases of tonsils and adenoids
0.000 0.348 0.652
H91.0 Ototoxic hearing loss
0.000 0.348 0.652
C60-C63 Malignant neoplasms of male genital organs
0.000 0.349 0.651
C86 Other specified types of T/NK-cell lymphoma
0.000 0.350 0.650
E88 Other metabolic disorders
0.000 0.351 0.649
C11.9 Nasopharynx, unspecified
0.000 0.352 0.647
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.353 0.647
C09.8 Overlapping lesion of tonsil
0.000 0.353 0.647
C09.0 Tonsillar fossa
0.000 0.353 0.647
J99 Respiratory disorders in diseases classified elsewhere
0.000 0.353 0.647
E61 Deficiency of other nutrient elements
0.000 0.353 0.647
E07 Other disorders of thyroid
0.000 0.354 0.646
M32 Systemic lupus erythematosus
0.000 0.354 0.645
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.355 0.644
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.356 0.644
C15 Malignant neoplasm of oesophagus
0.000 0.356 0.644
K72.0 Acute and subacute hepatic failure
0.000 0.356 0.644
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)
0.000 0.357 0.643
K65-K67 Diseases of peritoneum
0.000 0.357 0.643
E73 Lactose intolerance
0.000 0.358 0.642
L02 Cutaneous abscess, furuncle and carbuncle
0.000 0.358 0.642
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)
0.000 0.361 0.639
H40.5 Glaucoma secondary to other eye disorders
0.000 0.361 0.639
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)
0.000 0.362 0.638
H40.4 Glaucoma secondary to eye inflammation
0.000 0.362 0.638
K76.1 Chronic passive congestion of liver
0.000 0.363 0.637
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)
0.000 0.363 0.637
H60.5 Acute otitis externa, non-infective
0.000 0.364 0.636
M25.9 Joint disorder, unspecified
0.000 0.365 0.635
M12 Other specific arthropathies
0.000 0.365 0.635
C16 Malignant neoplasm of stomach
0.000 0.365 0.635
M25.7 Osteophyte
0.000 0.365 0.635
C00 Malignant neoplasm of lip
0.000 0.367 0.633
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)
0.000 0.367 0.633
M65.98 Synovitis and tenosynovitis, unspecified (Other)
0.000 0.367 0.633
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)
0.000 0.367 0.633
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.367 0.632
M65.49 Radial styloid tenosynovitis [de Quervain]-Site unspec
0.000 0.368 0.632
M65.48 Radial styloid tenosynovitis [de Quervain]-Other
0.000 0.368 0.632
M65.47 Radial styloid tenosynovitis [de Quervain]-Ankle/foot
0.000 0.368 0.632
M65.46 Radial styloid tenosynovitis [de Quervain]-Lower leg
0.000 0.368 0.632
M65.45 Radial styloid tenosynovitis [de Quervain]-Pelvic/thigh
0.000 0.368 0.632
M65.42 Radial styloid tenosynovitis [de Quervain]-Upper arm
0.000 0.368 0.632
M65.41 Radial styloid tenosynovitis [de Quervain]-Shldr region
0.000 0.368 0.632
M65.40 Radial styloid tenosynovitis [de Quervain] (Multiple sites)
0.000 0.368 0.632
C82.1 Mixed small cleaved and large cell, follicular
0.000 0.368 0.632
D89.0 Polyclonal hypergammaglobulinaemia
0.627 0.369 0.004
J31.0 Chronic rhinitis
0.000 0.369 0.631
M31.1 Thrombotic microangiopathy
0.000 0.370 0.630
K55 Vascular disorders of intestine
0.000 0.370 0.630
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.370 0.629
E45 Retarded development following protein-energy malnutrition
0.000 0.370 0.629
E43 Unspecified severe protein-energy malnutrition
0.000 0.370 0.629
E42 Marasmic kwashiorkor
0.000 0.370 0.629
E41 Nutritional marasmus
0.000 0.370 0.629
E40 Kwashiorkor
0.000 0.370 0.629
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.000 0.372 0.628
C06.0 Cheek mucosa
0.000 0.373 0.627
C10.9 Oropharynx, unspecified
0.000 0.374 0.626
E78.8 Other disorders of lipoprotein metabolism
0.000 0.375 0.625
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)
0.000 0.375 0.625
E79 Disorders of purine and pyrimidine metabolism
0.000 0.375 0.624
M60.0 Infective myositis
0.000 0.376 0.624
L43.3 Subacute (active) lichen planus
0.000 0.376 0.624
L43.2 Lichenoid drug reaction
0.000 0.376 0.624
L43.1 Bullous lichen planus
0.000 0.376 0.624
L43.0 Hypertrophic lichen planus
0.000 0.376 0.624
L44 Other papulosquamous disorders
0.000 0.378 0.622
L41 Parapsoriasis
0.000 0.378 0.622
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.378 0.622
M00-M03 Infectious arthropathies
0.000 0.378 0.622
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.000 0.379 0.621
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.379 0.621
K71 Toxic liver disease
0.000 0.379 0.621
H40.3 Glaucoma secondary to eye trauma
0.000 0.379 0.621
K74.0 Hepatic fibrosis
0.000 0.381 0.618
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.000 0.383 0.617

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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