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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs9269911
log Bayes Factor = 213.873
Chromosome 6   position 32,551,382  (GRCh37) Explore rs9269911 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
H36.0 Diabetic retinopathy
0.000 0.000 1.000
J45.9 Asthma, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
Chapter XI Diseases of the digestive system
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
# Top node
0.000 0.000 1.000
E16.2 Hypoglycaemia, unspecified
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
J40-J47 Chronic lower respiratory diseases
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
M05-M14 Inflammatory polyarthropathies
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
E16 Other disorders of pancreatic internal secretion
0.000 0.000 1.000
K51.9 Ulcerative colitis, unspecified
1.000 0.000 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.000 1.000
J45 Asthma
0.000 0.000 1.000
K51 Ulcerative colitis
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
0.000 0.000 1.000
M05 Seropositive rheumatoid arthritis
0.000 0.000 1.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.000 1.000
H36 Retinal disorders in diseases classified elsewhere
0.000 0.000 1.000
H30-H36 Disorders of choroid and retina
0.000 0.000 1.000
E10.4 With neurological complications
0.000 0.001 0.999
Chapter X Diseases of the respiratory system
0.000 0.001 0.999
K90 Intestinal malabsorption
0.000 0.001 0.999
E14.9 Without complications
0.000 0.001 0.999
K90-K93 Other diseases of the digestive system
0.000 0.001 0.999
J44 Other chronic obstructive pulmonary disease
0.000 0.001 0.999
G35-G37 Demyelinating diseases of the central nervous system
0.998 0.002 0.000
G37 Other demyelinating diseases of central nervous system
0.998 0.002 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.002 0.998
G37.9 Demyelinating disease of central nervous system, unspecified
0.997 0.003 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.003 0.997
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.000 0.003 0.997
E83.1 Disorders of iron metabolism
0.997 0.003 0.000
E14.3 With ophthalmic complications
0.000 0.004 0.996
K51.3 Ulcerative (chronic) rectosigmoiditis
0.995 0.005 0.000
K70-K77 Diseases of liver
0.000 0.006 0.994
H43-H45 Disorders of vitreous body and globe
0.000 0.010 0.990
K82 Other diseases of gallbladder
0.000 0.011 0.989
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.011 0.989
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.012 0.988
E78.0 Pure hypercholesterolaemia
0.000 0.012 0.988
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.000 0.012 0.988
H43 Disorders of vitreous body
0.000 0.014 0.986
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.015 0.985
E70-E90 Metabolic disorders
0.000 0.018 0.982
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.018 0.982
K82.8 Other specified diseases of gallbladder
0.000 0.019 0.981
K74 Fibrosis and cirrhosis of liver
0.000 0.021 0.979
E11.3 With ophthalmic complications
0.000 0.021 0.979
L40-L45 Papulosquamous disorders
0.000 0.023 0.977
I20-I25 Ischaemic heart diseases
0.000 0.023 0.977
Chapter IX Diseases of the circulatory system
0.000 0.023 0.977
J33.9 Nasal polyp, unspecified
0.000 0.023 0.977
J33 Nasal polyp
0.000 0.024 0.976
L43 Lichen planus
0.000 0.024 0.976
L40 Psoriasis
0.000 0.025 0.975
L43.9 Lichen planus, unspecified
0.000 0.026 0.974
E10.5 With peripheral circulatory complications
0.000 0.027 0.973
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.031 0.969
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.031 0.969
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.033 0.967
L40.5 Arthropathic psoriasis
0.000 0.033 0.967
I10-I15 Hypertensive diseases
0.000 0.033 0.967
K51.8 Other ulcerative colitis
0.965 0.035 0.000
J30-J39 Other diseases of upper respiratory tract
0.000 0.037 0.963
H43.3 Other vitreous opacities
0.000 0.039 0.961
K74.3 Primary biliary cirrhosis
0.000 0.042 0.958
H40-H42 Glaucoma
0.000 0.043 0.957
E11.1 With ketoacidosis
0.000 0.043 0.957
E05.9 Thyrotoxicosis, unspecified
0.000 0.043 0.957
H25-H28 Disorders of lens
0.000 0.044 0.956
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.046 0.954
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.048 0.952
K86 Other diseases of pancreas
0.000 0.048 0.952
I22 Subsequent myocardial infarction
0.000 0.050 0.950
E06 Thyroiditis
0.000 0.053 0.947
J33.8 Other polyp of sinus
0.000 0.054 0.946
H34 Retinal vascular occlusions
0.000 0.055 0.945
K55-K64 Other diseases of intestines
0.000 0.055 0.945
J43 Emphysema
0.000 0.055 0.945
K50-K52 Noninfective enteritis and colitis
0.015 0.055 0.930
I20 Angina pectoris
0.000 0.056 0.944
H43.8 Other disorders of vitreous body
0.000 0.058 0.942
K81 Cholecystitis
0.000 0.058 0.942
J46 Status asthmaticus
0.000 0.060 0.940
E10.2 With renal complications
0.000 0.062 0.938
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.063 0.937
M06.0 Seronegative rheumatoid arthritis
0.000 0.071 0.929
H40 Glaucoma
0.000 0.073 0.927
K72 Hepatic failure, not elsewhere classified
0.000 0.076 0.924
I10 Essential (primary) hypertension
0.000 0.077 0.923
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.078 0.922
K60 Fissure and fistula of anal and rectal regions
0.000 0.078 0.922
H25.1 Senile nuclear cataract
0.000 0.083 0.917
H25 Senile cataract
0.000 0.083 0.917
K75 Other inflammatory liver diseases
0.000 0.084 0.916
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.085 0.915
H40.9 Glaucoma, unspecified
0.000 0.085 0.915
E06.3 Autoimmune thyroiditis
0.000 0.090 0.910
M07 Psoriatic and enteropathic arthropathies
0.000 0.090 0.910
K81.1 Chronic cholecystitis
0.000 0.092 0.908
E11.5 With peripheral circulatory complications
0.000 0.098 0.902
J86 Pyothorax
0.000 0.099 0.901
J43.9 Emphysema, unspecified
0.000 0.102 0.898
E03.8 Other specified hypothyroidism
0.000 0.104 0.896
E13 Other specified diabetes mellitus
0.000 0.106 0.894
L40.9 Psoriasis, unspecified
0.000 0.106 0.894
H27 Other disorders of lens
0.000 0.110 0.890
E07 Other disorders of thyroid
0.000 0.110 0.890
K86.2 Cyst of pancreas
0.000 0.110 0.890
E78.5 Hyperlipidaemia, unspecified
0.000 0.110 0.890
K58 Irritable bowel syndrome
0.000 0.111 0.889
E11.2 With renal complications
0.000 0.111 0.889
K75.4 Autoimmune hepatitis
0.000 0.114 0.886
K82.1 Hydrops of gallbladder
0.000 0.116 0.884
K60.2 Anal fissure, unspecified
0.000 0.117 0.883
I20.1 Angina pectoris with documented spasm
0.000 0.118 0.882
K58.0 Irritable bowel syndrome with diarrhoea
0.000 0.125 0.875
E11.6 With other specified complications
0.000 0.125 0.875
K51.2 Ulcerative (chronic) proctitis
0.874 0.126 0.000
I20.0 Unstable angina
0.000 0.127 0.873
K50 Crohn's disease [regional enteritis]
0.001 0.129 0.871
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.137 0.863
K51.4 Pseudopolyposis of colon
0.863 0.137 0.000
I24 Other acute ischaemic heart diseases
0.000 0.139 0.861
M06.3 Rheumatoid nodule
0.000 0.139 0.861
H34.8 Other retinal vascular occlusions
0.000 0.142 0.858
K60.0 Acute anal fissure
0.000 0.142 0.858
K74.5 Biliary cirrhosis, unspecified
0.000 0.145 0.855
I25 Chronic ischaemic heart disease
0.000 0.145 0.855
I12 Hypertensive renal disease
0.000 0.148 0.852
M07.3 Other psoriatic arthropathies
0.000 0.155 0.845
K81.9 Cholecystitis, unspecified
0.000 0.159 0.841
J86.9 Pyothorax without fistula
0.000 0.163 0.837
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.166 0.834
K86.1 Other chronic pancreatitis
0.000 0.169 0.831
I20.9 Angina pectoris, unspecified
0.000 0.170 0.830
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.170 0.830
M65-M68 Disorders of synovium and tendon
0.000 0.171 0.829
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.172 0.828
H40.1 Primary open-angle glaucoma
0.000 0.172 0.828
E07.9 Disorder of thyroid, unspecified
0.000 0.173 0.827
K72.9 Hepatic failure, unspecified
0.000 0.173 0.827
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.175 0.825
G37.8 Other specified demyelinating diseases of central nervous system
0.823 0.177 0.000
K62 Other diseases of anus and rectum
0.000 0.178 0.822
K73 Chronic hepatitis, not elsewhere classified
0.000 0.178 0.822
I15 Secondary hypertension
0.000 0.180 0.820
E13.9 Without complications
0.000 0.182 0.818
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.183 0.817
K63 Other diseases of intestine
0.000 0.185 0.815
M06.4 Inflammatory polyarthropathy
0.000 0.189 0.811
K51.5 Mucosal proctocolitis
0.809 0.191 0.000
I25.5 Ischaemic cardiomyopathy
0.000 0.193 0.807
J95-J99 Other diseases of the respiratory system
0.000 0.194 0.806
K55 Vascular disorders of intestine
0.000 0.194 0.806
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.804 0.196 0.000
K60.5 Anorectal fistula
0.000 0.200 0.800
K62.1 Rectal polyp
0.000 0.201 0.799
J86.0 Pyothorax with fistula
0.000 0.203 0.797
E78.1 Pure hyperglyceridaemia
0.000 0.203 0.797
E16.1 Other hypoglycaemia
0.000 0.205 0.795
J33.0 Polyp of nasal cavity
0.000 0.206 0.794
K72.0 Acute and subacute hepatic failure
0.000 0.209 0.791
M14 Arthropathies in other diseases classified elsewhere
0.000 0.209 0.790
K63.9 Disease of intestine, unspecified
0.000 0.211 0.789
E83 Disorders of mineral metabolism
0.697 0.211 0.092
J44.9 Chronic obstructive pulmonary disease, unspecified
0.000 0.212 0.788
H27.0 Aphakia
0.000 0.212 0.788
K86.3 Pseudocyst of pancreas
0.000 0.213 0.787
H34.2 Other retinal artery occlusions
0.000 0.217 0.783
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.217 0.782
J37 Chronic laryngitis and laryngotracheitis
0.000 0.218 0.782
E40-E46 Malnutrition
0.000 0.218 0.782
K90.9 Intestinal malabsorption, unspecified
0.000 0.220 0.780
I25.2 Old myocardial infarction
0.000 0.222 0.778
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.225 0.775
K62.4 Stenosis of anus and rectum
0.000 0.225 0.775
K50.8 Other Crohn's disease
0.000 0.226 0.774
L43.8 Other lichen planus
0.000 0.229 0.771
I11 Hypertensive heart disease
0.000 0.236 0.764
L40.8 Other psoriasis
0.000 0.236 0.764
E11.8 With unspecified complications
0.000 0.236 0.764
H27.8 Other specified disorders of lens
0.000 0.239 0.761
I12.9 Hypertensive renal disease without renal failure
0.000 0.239 0.761
M70-M79 Other soft tissue disorders
0.000 0.240 0.760
K50.1 Crohn's disease of large intestine
0.000 0.240 0.760
K82.9 Disease of gallbladder, unspecified
0.000 0.241 0.759
K52 Other non-infective gastro-enteritis and colitis
0.003 0.243 0.754
H34.1 Central retinal artery occlusion
0.000 0.246 0.754
H40.5 Glaucoma secondary to other eye disorders
0.000 0.247 0.753
E88 Other metabolic disorders
0.000 0.247 0.753
Chapter VIII Diseases of the ear and mastoid process
0.000 0.248 0.752
E78.2 Mixed hyperlipidaemia
0.000 0.250 0.750
M65 Synovitis and tenosynovitis
0.000 0.250 0.750
H43.9 Disorder of vitreous body, unspecified
0.000 0.253 0.747
K74.6 Other and unspecified cirrhosis of liver
0.000 0.254 0.746
H43.1 Vitreous haemorrhage
0.000 0.257 0.743
K63.3 Ulcer of intestine
0.000 0.260 0.740
H60-H62 Diseases of external ear
0.000 0.261 0.739
K82.3 Fistula of gallbladder
0.000 0.264 0.736
E11.0 With coma
0.000 0.266 0.734
M11 Other crystal arthropathies
0.000 0.269 0.731
M06.34 Rheumatoid nodule (Hand)
0.000 0.270 0.730
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.271 0.729
K82.2 Perforation of gallbladder
0.000 0.276 0.724
J32 Chronic sinusitis
0.000 0.277 0.723
E74 Other disorders of carbohydrate metabolism
0.000 0.278 0.722
H30 Chorioretinal inflammation
0.000 0.278 0.722
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.278 0.722
K86.0 Alcohol-induced chronic pancreatitis
0.000 0.279 0.721
I23 Certain current complications following acute myocardial infarction
0.000 0.281 0.719
H61 Other disorders of external ear
0.000 0.282 0.718
K51.0 Ulcerative (chronic) enterocolitis
0.718 0.282 0.000
E11.4 With neurological complications
0.000 0.282 0.718
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
E10.8 With unspecified complications
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E10.6 With other specified complications
0.000 0.283 0.717
E10.0 With coma
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
M06.8 Other specified rheumatoid arthritis
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.283 0.717
E14.8 With unspecified complications
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.6 With other specified complications
0.000 0.283 0.717
E14.5 With peripheral circulatory complications
0.000 0.283 0.717
E14.4 With neurological complications
0.000 0.283 0.717
E14.2 Withrenal complications
0.000 0.283 0.717
E14.1 With ketoacidosis
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.717
M08 Juvenile arthritis
0.000 0.283 0.717
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.283 0.717
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.283 0.717
E16.4 Abnormal secretion of gastrin
0.000 0.283 0.717
E16.3 Increased secretion of glucagon
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.717
J45.8 Mixed asthma
0.000 0.283 0.717
J45.1 Nonallergic asthma
0.000 0.283 0.717
K51.1 Ulcerative (chronic) ileocolitis
0.717 0.283 0.000
J43.2 Centrilobular emphysema
0.000 0.283 0.717
M05.8 Other seropositive rheumatoid arthritis
0.000 0.283 0.717
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.283 0.717
M05.2 Rheumatoid vasculitis
0.000 0.283 0.717
M05.1 Rheumatoid lung disease
0.000 0.283 0.717
M05.0 Felty's syndrome
0.000 0.283 0.717
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.283 0.717
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.283 0.717
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.283 0.717
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.283 0.717
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.283 0.717
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.283 0.717
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.283 0.717
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.283 0.717
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.283 0.717
K90.3 Pancreatic steatorrhoea
0.000 0.284 0.716
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.284 0.716
K90.1 Tropical sprue
0.000 0.284 0.716
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.284 0.716
G36 Other acute disseminated demyelination
0.716 0.284 0.000
G37.5 Concentric sclerosis [Balo]
0.715 0.284 0.000
G37.4 Subacute necrotising myelitis
0.715 0.284 0.000
G37.2 Central pontine myelinolysis
0.715 0.284 0.000
G37.1 Central demyelination of corpus callosum
0.715 0.284 0.000
G37.0 Diffuse sclerosis
0.715 0.284 0.000
M77 Other enthesopathies
0.000 0.285 0.715
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.000 0.285 0.715
K77 Liver disorders in diseases classified elsewhere
0.000 0.287 0.713
K71 Toxic liver disease
0.000 0.287 0.713
K55.2 Angiodysplasia of colon
0.000 0.288 0.712
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.290 0.710
J98 Other respiratory disorders
0.000 0.290 0.710
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.000 0.290 0.710
K86.8 Other specified diseases of pancreas
0.000 0.292 0.708
M77.1 Lateral epicondylitis
0.000 0.293 0.707
H43.2 Crystalline deposits in vitreous body
0.000 0.293 0.707
H43.0 Vitreous prolapse
0.000 0.293 0.707
E78.6 Lipoprotein deficiency
0.000 0.294 0.706
E78.3 Hyperchylomicronaemia
0.000 0.294 0.706
M65.4 Radial styloid tenosynovitis [de Quervain]
0.000 0.295 0.705
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.296 0.704
E77 Disorders of glycoprotein metabolism
0.000 0.296 0.704
E76 Disorders of glycosaminoglycan metabolism
0.000 0.296 0.704
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.296 0.704
E72 Other disorders of amino-acid metabolism
0.000 0.296 0.704
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.296 0.704
E70 Disorders of aromatic amino-acid metabolism
0.000 0.296 0.704
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.296 0.704
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.297 0.703
M77.12 Lateral epicondylitis (Upper arm)
0.000 0.297 0.703
K74.4 Secondary biliary cirrhosis
0.000 0.298 0.702
K74.2 Hepatic fibrosis with hepatic sclerosis
0.000 0.298 0.702
K74.1 Hepatic sclerosis
0.000 0.298 0.702
L44 Other papulosquamous disorders
0.000 0.299 0.701
L41 Parapsoriasis
0.000 0.299 0.701
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.299 0.701
I00-I02 Acute rheumatic fever
0.000 0.299 0.700
J41 Simple and mucopurulent chronic bronchitis
0.000 0.300 0.700
J33.1 Polypoid sinus degeneration
0.000 0.300 0.700
L43.3 Subacute (active) lichen planus
0.000 0.300 0.699
L43.2 Lichenoid drug reaction
0.000 0.300 0.699
L43.1 Bullous lichen planus
0.000 0.300 0.699
L43.0 Hypertrophic lichen planus
0.000 0.300 0.699
L40.4 Guttate psoriasis
0.000 0.301 0.699
L40.3 Pustulosis palmaris et plantaris
0.000 0.301 0.699
L40.2 Acrodermatitis continua
0.000 0.301 0.699
L40.1 Generalised pustular psoriasis
0.000 0.301 0.699
E05.5 Thyroid crisis or storm
0.000 0.305 0.695
E05.4 Thyrotoxicosis factitia
0.000 0.305 0.695
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.305 0.695
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.305 0.695
K50.0 Crohn's disease of small intestine
0.000 0.307 0.693
I13 Hypertensive heart and renal disease
0.000 0.307 0.693
H40.4 Glaucoma secondary to eye inflammation
0.000 0.307 0.693
M14.6 Neuropathic arthropathy
0.000 0.308 0.692
K55.8 Other vascular disorders of intestine
0.000 0.310 0.690
I15.1 Hypertension secondary to other renal disorders
0.000 0.312 0.688
K62.0 Anal polyp
0.000 0.312 0.688
K63.4 Enteroptosis
0.000 0.313 0.687
H42 Glaucoma in diseases classified elsewhere
0.000 0.313 0.686
K52.1 Toxic gastro-enteritis and colitis
0.001 0.314 0.685
K75.9 Inflammatory liver disease, unspecified
0.000 0.314 0.686
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.000 0.314 0.686
M12 Other specific arthropathies
0.000 0.316 0.683
K81.8 Other cholecystitis
0.000 0.318 0.682
H61.0 Perichondritis of external ear
0.000 0.320 0.680
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.320 0.680
E06.5 Other chronic thyroiditis
0.000 0.321 0.679
E06.4 Drug-induced thyroiditis
0.000 0.321 0.679
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.321 0.679
E06.1 Subacute thyroiditis
0.000 0.321 0.679
E06.0 Acute thyroiditis
0.000 0.321 0.679
H34.0 Transient retinal artery occlusion
0.000 0.322 0.678
K64 Haemorrhoids and perianal venous thrombosis
0.000 0.322 0.677
J43.8 Other emphysema
0.000 0.323 0.677
J43.1 Panlobular emphysema
0.000 0.323 0.677
J43.0 MacLeod's syndrome
0.000 0.323 0.677
K62.7 Radiation proctitis
0.000 0.323 0.677
K73.9 Chronic hepatitis, unspecified
0.000 0.323 0.677
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.324 0.676
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.326 0.674
J98.4 Other disorders of lung
0.000 0.326 0.674
I21 Acute myocardial infarction
0.000 0.327 0.673
E06.9 Thyroiditis, unspecified
0.000 0.328 0.672
E05.8 Other thyrotoxicosis
0.000 0.330 0.670
H34.9 Retinal vascular occlusion, unspecified
0.000 0.331 0.668
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.334 0.666
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.334 0.666
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.334 0.666
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.334 0.666
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.334 0.666
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.334 0.666
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.334 0.666
H27.1 Dislocation of lens
0.000 0.334 0.666
H40.6 Glaucoma secondary to drugs
0.000 0.335 0.665
H40.3 Glaucoma secondary to eye trauma
0.000 0.335 0.665
K72.1 Chronic hepatic failure
0.000 0.337 0.663
E84 Cystic fibrosis
0.000 0.341 0.659
H25.2 Senile cataract, morgagnian type
0.000 0.343 0.657
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.343 0.656
K75.2 Nonspecific reactive hepatitis
0.000 0.343 0.656
K75.1 Phlebitis of portal vein
0.000 0.343 0.656
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.344 0.656
J37.0 Chronic laryngitis
0.000 0.347 0.653
M07.6 Other enteropathic arthropathies
0.000 0.348 0.652
M07.5 Arthropathy in ulcerative colitis
0.000 0.348 0.652
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.348 0.652
M07.2 Psoriatic spondylitis
0.000 0.348 0.652
M07.1 Arthritis mutilans
0.000 0.348 0.652
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.348 0.652
K82.0 Obstruction of gallbladder
0.000 0.349 0.651
H60 Otitis externa
0.000 0.350 0.650
J42 Unspecified chronic bronchitis
0.000 0.351 0.649
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.352 0.648
K52.8 Other specified non-infective gastro-enteritis and colitis
0.001 0.355 0.645
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.356 0.644
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)
0.000 0.357 0.643
E13.8 With unspecified complications
0.000 0.359 0.641
E13.7 With multiple complications
0.000 0.359 0.641
E13.6 With other specified complications
0.000 0.359 0.641
E13.5 With peripheral circulatory complications
0.000 0.359 0.641
E13.4 With neurological complications
0.000 0.359 0.641
E13.3 With ophthalmic complications
0.000 0.359 0.641
E13.2 With renal complications
0.000 0.359 0.641
E13.1 With ketoacidosis
0.000 0.359 0.641
E13.0 With coma
0.000 0.359 0.641
H27.9 Disorder of lens, unspecified
0.000 0.361 0.638
E07.1 Dyshormogenetic goitre
0.000 0.362 0.638
E07.0 Hypersecretion of calcitonin
0.000 0.362 0.638
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.362 0.638
M65.9 Synovitis and tenosynovitis, unspecified
0.000 0.363 0.637
I12.0 Hypertensive renal disease with renal failure
0.000 0.365 0.635
I15.9 Seconday hypertension, unspecified
0.000 0.366 0.634
I21.4 Acute subendocardial myocardial infarction
0.000 0.367 0.633
L10-L14 Bullous disorders
0.000 0.367 0.632
E83.3 Disorders of phosphorus metabolism
0.601 0.368 0.031
E79 Disorders of purine and pyrimidine metabolism
0.000 0.368 0.631
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.372 0.628
L42 Pityriasis rosea
0.000 0.374 0.626
E46 Unspecified protein-energy malnutrition
0.000 0.374 0.626
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.374 0.626
E83.9 Disorder of mineral metabolism, unspecified
0.571 0.375 0.054
K60.1 Chronic anal fissure
0.000 0.379 0.621
K90.8 Other intestinal malabsorption
0.000 0.379 0.621
M66 Spontaneous rupture of synovium and tendon
0.000 0.380 0.620
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.382 0.617
M06.38 Rheumatoid nodule (Other)
0.000 0.382 0.617
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.382 0.617
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.382 0.617
M06.33 Rheumatoid nodule (Forearm)
0.000 0.382 0.617
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.382 0.617
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.382 0.617
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.382 0.617
E03.1 Congenital hypothyroidism without goitre
0.000 0.383 0.616
K55.1 Chronic vascular disorders of intestine
0.000 0.385 0.615
I25.6 Silent myocardial ischaemia
0.000 0.387 0.613
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.387 0.613
K63.2 Fistula of intestine
0.000 0.388 0.612
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.389 0.611
M10 Gout
0.000 0.390 0.610
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.390 0.610
J85 Abscess of lung and mediastinum
0.000 0.391 0.609
H61.1 Non-infective disorders of pinna
0.000 0.391 0.608
M07.38 Other psoriatic arthropathies (Other)
0.000 0.394 0.606
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.394 0.606
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.394 0.606
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.394 0.606
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.394 0.606
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.394 0.606
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.394 0.606
H61.8 Other specified disorders of external ear
0.000 0.394 0.606
K74.0 Hepatic fibrosis
0.000 0.395 0.605
M72 Fibroblastic disorders
0.000 0.396 0.604
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)
0.000 0.398 0.602
K80 Cholelithiasis
0.000 0.399 0.601
E78.8 Other disorders of lipoprotein metabolism
0.000 0.399 0.601
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.000 0.400 0.600
M45-M49 Spondylopathies
0.000 0.400 0.600
J32.4 Chronic pansinusitis
0.000 0.400 0.600
K62.2 Anal prolapse
0.000 0.401 0.599
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.000 0.405 0.595
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.000 0.406 0.594
J60-J70 Lung diseases due to external agents
0.000 0.408 0.592
E73 Lactose intolerance
0.000 0.408 0.591
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.410 0.590
L40.0 Psoriasis vulgaris
0.000 0.410 0.590
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.410 0.590
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.000 0.410 0.590
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.000 0.410 0.590
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.412 0.588
I15.8 Other secondary hypertension
0.000 0.412 0.588
I15.2 Hypertension secondary to endocrine disorders
0.000 0.412 0.588
I15.0 Renovascular hypertension
0.000 0.412 0.588
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.416 0.584
I25.3 Aneurysm of heart
0.000 0.417 0.583
J32.9 Chronic sinusitis, unspecified
0.000 0.418 0.582
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.419 0.581
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.419 0.581
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.419 0.581
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.419 0.581
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.419 0.581
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.419 0.581
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.419 0.581
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.419 0.581
M45 Ankylosing spondylitis
0.000 0.419 0.581
M60-M63 Disorders of muscles
0.000 0.420 0.579
K80.2 Calculus of gallbladder without cholecystitis
0.000 0.421 0.579
J96 Respiratory failure, not elsewhere classified
0.000 0.422 0.578
H61.3 Acquired stenosis of external ear canal
0.000 0.425 0.575
J95 Postprocedural respiratory disorders, not elsewhere classified
0.000 0.425 0.575
E07.8 Other specified disorders of thyroid
0.000 0.426 0.574
K91.3 Postoperative intestinal obstruction
0.000 0.426 0.574
J98.6 Disorders of diaphragm
0.000 0.428 0.572
K91.0 Vomiting following gastro-intestinal surgery
0.000 0.429 0.571

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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