TreeWAS – Variant ID: rs9275595

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	1.000	0.000	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	1.000	0.000	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	1.000	0.000	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	1.000	0.000	0.000
E10.9 Without complications	1.000	0.000	0.000
E10.3 With ophthalmic complications	1.000	0.000	0.000
E10.1 With ketoacidosis	1.000	0.000	0.000
E16.2 Hypoglycaemia, unspecified	1.000	0.000	0.000
H36.0 Diabetic retinopathy	1.000	0.000	0.000
J33.9 Nasal polyp, unspecified	1.000	0.000	0.000
K90.0 Coeliac disease	0.000	0.000	1.000
M05.9 Seropositive rheumatoid arthritis, unspecified	1.000	0.000	0.000
M06.9 Rheumatoid arthritis, unspecified	1.000	0.000	0.000
M35.3 Polymyalgia rheumatica	1.000	0.000	0.000
E10 Insulin-dependent diabetes mellitus	1.000	0.000	0.000
J33 Nasal polyp	1.000	0.000	0.000
M06 Other rheumatoid arthritis	1.000	0.000	0.000
E10-E14 Diabetes mellitus	1.000	0.000	0.000
J30-J39 Other diseases of upper respiratory tract	1.000	0.000	0.000
M20-M25 Other joint disorders	1.000	0.000	0.000
M05-M14 Inflammatory polyarthropathies	1.000	0.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000	0.000
Chapter X Diseases of the respiratory system	1.000	0.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000	0.000
# Top node	1.000	0.000	0.000
E11 Non-insulin-dependent diabetes mellitus	1.000	0.000	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	1.000	0.000	0.000
E10.4 With neurological complications	1.000	0.000	0.000
G35 Multiple sclerosis	0.000	0.000	1.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	1.000	0.000	0.000
M05 Seropositive rheumatoid arthritis	1.000	0.000	0.000
E16 Other disorders of pancreatic internal secretion	1.000	0.000	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	1.000	0.000	0.000
J32 Chronic sinusitis	1.000	0.000	0.000
M35 Other systemic involvement of connective tissue	1.000	0.000	0.000
M45 Ankylosing spondylitis	1.000	0.000	0.000
E11.9 Without complications	1.000	0.000	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	1.000	0.000	0.000
E14 Unspecified diabetes mellitus	1.000	0.000	0.000
J32.9 Chronic sinusitis, unspecified	1.000	0.000	0.000
M45-M49 Spondylopathies	0.999	0.001	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.999	0.001	0.000
E10.5 With peripheral circulatory complications	0.999	0.001	0.000
M06.3 Rheumatoid nodule	0.998	0.002	0.000
M65-M68 Disorders of synovium and tendon	0.998	0.002	0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.998	0.002	0.000
J33.0 Polyp of nasal cavity	0.997	0.003	0.000
M06.0 Seronegative rheumatoid arthritis	0.997	0.003	0.000
Chapter VII Diseases of the eye and adnexa	0.996	0.004	0.000
H36 Retinal disorders in diseases classified elsewhere	0.996	0.004	0.000
E14.3 With ophthalmic complications	0.996	0.004	0.000
M25 Other joint disorders, not elsewhere classified	0.995	0.005	0.000
M65 Synovitis and tenosynovitis	0.995	0.005	0.000
M25.4 Effusion of joint	0.994	0.006	0.000
E10.2 With renal complications	0.994	0.006	0.000
M65.9 Synovitis and tenosynovitis, unspecified	0.994	0.006	0.000
H30-H36 Disorders of choroid and retina	0.994	0.006	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.991	0.009	0.000
Chapter V Mental and behavioural disorders	0.988	0.012	0.000
L00-L08 Infections of the skin and subcutaneous tissue	0.987	0.013	0.000
M25.46 Effusion of joint (Lower leg)	0.987	0.013	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.986	0.014	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.982	0.018	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.979	0.021	0.000
M31 Other necrotising vasculopathies	0.979	0.021	0.000
M06.34 Rheumatoid nodule (Hand)	0.979	0.021	0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.978	0.022	0.000
E11.3 With ophthalmic complications	0.977	0.023	0.000
L02 Cutaneous abscess, furuncle and carbuncle	0.976	0.024	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.974	0.026	0.000
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)	0.972	0.028	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.967	0.033	0.000
F30-F39 Mood [affective] disorders	0.961	0.039	0.000
J00-J06 Acute upper respiratory infections	0.961	0.039	0.000
M34 Systemic sclerosis	0.960	0.040	0.000
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)	0.960	0.040	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.957	0.043	0.000
J09-J18 Influenza and pneumonia	0.952	0.048	0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)	0.948	0.052	0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.943	0.057	0.000
F20 Schizophrenia	0.942	0.058	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.941	0.059	0.000
E14.9 Without complications	0.940	0.060	0.000
M00-M03 Infectious arthropathies	0.939	0.061	0.000
F60-F69 Disorders of adult personality and behaviour	0.939	0.061	0.000
H40-H42 Glaucoma	0.939	0.061	0.000
M25.40 Effusion of joint (Multiple sites)	0.939	0.061	0.000
K90 Intestinal malabsorption	0.000	0.062	0.938
M07 Psoriatic and enteropathic arthropathies	0.937	0.063	0.000
L08 Other local infections of skin and subcutaneous tissue	0.930	0.070	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.928	0.072	0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb	0.927	0.073	0.000
E10.6 With other specified complications	0.923	0.077	0.000
E10.0 With coma	0.919	0.081	0.000
M30 Polyarteritis nodosa and related conditions	0.917	0.083	0.000
H20 Iridocyclitis	0.916	0.084	0.000
F33 Recurrent depressive disorder	0.916	0.084	0.000
F60 Specific personality disorders	0.916	0.084	0.000
J06 Acute upper respiratory infections of multiple and unspecified sites	0.915	0.085	0.000
M66 Spontaneous rupture of synovium and tendon	0.914	0.086	0.000
E14.6 With other specified complications	0.913	0.087	0.000
E10.8 With unspecified complications	0.913	0.087	0.000
F20.0 Paranoid schizophrenia	0.912	0.088	0.000
M24 Other specific joint derangements	0.905	0.095	0.000
L02.1 Cutaneous abscess, furuncle and carbuncle of neck	0.905	0.095	0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.902	0.098	0.000
F32 Depressive episode	0.901	0.099	0.000
L03 Cellulitis	0.900	0.100	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.899	0.101	0.000
H40 Glaucoma	0.898	0.102	0.000
J32.1 Chronic frontal sinusitis	0.895	0.105	0.000
M00 Pyogenic arthritis	0.892	0.108	0.000
M07.3 Other psoriatic arthropathies	0.891	0.109	0.000
H40.9 Glaucoma, unspecified	0.888	0.112	0.000
F32.3 Severe depressive episode with psychotic symptoms	0.886	0.114	0.000
K90.9 Intestinal malabsorption, unspecified	0.000	0.116	0.884
M06.37 Rheumatoid nodule (Ankle and foot)	0.884	0.116	0.000
F33.9 Recurrent depressive disorder, unspecified	0.883	0.117	0.000
M06.32 Rheumatoid nodule (Upper arm)	0.882	0.118	0.000
J06.9 Acute upper respiratory infection, unspecified	0.882	0.118	0.000
J15 Bacterial pneumonia, not elsewhere classified	0.881	0.119	0.000
M34.9 Systemic sclerosis, unspecified	0.881	0.119	0.000
E11.4 With neurological complications	0.880	0.120	0.000
M31.7 Microscopic polyangiitis	0.876	0.124	0.000
J32.4 Chronic pansinusitis	0.875	0.125	0.000
M14 Arthropathies in other diseases classified elsewhere	0.875	0.125	0.000
M20 Acquired deformities of fingers and toes	0.873	0.127	0.000
M25.47 Effusion of joint (Ankle and foot)	0.873	0.127	0.000
J40-J47 Chronic lower respiratory diseases	0.866	0.134	0.000
C82.0 Small cleaved cell, follicular	0.865	0.135	0.000
E11.0 With coma	0.864	0.136	0.000
J35 Chronic diseases of tonsils and adenoids	0.862	0.138	0.000
M31.6 Other giant cell arteritis	0.862	0.138	0.000
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock	0.860	0.140	0.000
M60-M63 Disorders of muscles	0.859	0.141	0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.855	0.145	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.147	0.853
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.852	0.147	0.000
M20.6 Acquired deformity of toe(s), unspecified	0.850	0.150	0.000
F20.9 Schizophrenia, unspecified	0.849	0.151	0.000
L03.8 Cellulitis of other sites	0.846	0.154	0.000
L03.2 Cellulitis of face	0.846	0.154	0.000
F60.3 Emotionally unstable personality disorder	0.843	0.157	0.000
J33.8 Other polyp of sinus	0.843	0.157	0.000
H21 Other disorders of iris and ciliary body	0.842	0.158	0.000
M00.9 Pyogenic arthritis, unspecified	0.840	0.160	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.840	0.160	0.000
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites	0.836	0.164	0.000
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)	0.836	0.164	0.000
J11 Influenza, virus not identified	0.836	0.164	0.000
H53-H54 Visual disturbances and blindness	0.836	0.164	0.000
H20.8 Other iridocyclitis	0.834	0.166	0.000
M06.36 Rheumatoid nodule (Lower leg)	0.834	0.166	0.000
M66.3 Spontaneous rupture of flexor tendons	0.832	0.168	0.000
L08.9 Local infection of skin and subcutaneous tissue, unspecified	0.832	0.168	0.000
M20.1 Hallux valgus (acquired)	0.830	0.170	0.000
J31.0 Chronic rhinitis	0.829	0.171	0.000
M45.X2 Ankylosing spondylitis (Cervical region)	0.826	0.174	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.826	0.174	0.000
M34.1 CR(E)ST syndrome	0.825	0.175	0.000
J20-J22 Other acute lower respiratory infections	0.824	0.176	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.822	0.178	0.000
L08.8 Other specified local infections of skin and subcutaneous tissue	0.821	0.179	0.000
F32.2 Severe depressive episode without psychotic symptoms	0.821	0.179	0.000
M25.43 Effusion of joint (Forearm)	0.820	0.180	0.000
L40-L45 Papulosquamous disorders	0.820	0.180	0.000
J10 Influenza due to identified influenza virus	0.820	0.180	0.000
J33.1 Polypoid sinus degeneration	0.819	0.181	0.000
M25.0 Haemarthrosis	0.819	0.181	0.000
E10.7 With multiple complications	0.819	0.181	0.000
J80-J84 Other respiratory diseases principally affecting the interstitium	0.818	0.182	0.000
M12 Other specific arthropathies	0.817	0.183	0.000
Chapter II Neoplasms	0.815	0.185	0.000
M65.1 Other infective (teno)synovitis	0.813	0.187	0.000
M46 Other inflammatory spondylopathies	0.811	0.189	0.000
L04 Acute lymphadenitis	0.810	0.190	0.000
J00 Acute nasopharyngitis [common cold]	0.809	0.191	0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.809	0.191	0.000
E11.1 With ketoacidosis	0.809	0.191	0.000
M24.5 Contracture of joint	0.808	0.192	0.000
J47 Bronchiectasis	0.807	0.193	0.000
F60.5 Anankastic personality disorder	0.807	0.193	0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.803	0.197	0.000
J35.1 Hypertrophy of tonsils	0.802	0.198	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.799	0.201	0.000
M66.2 Spontaneous rupture of extensor tendons	0.797	0.203	0.000
M06.8 Other specified rheumatoid arthritis	0.796	0.204	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.795	0.205	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.794	0.206	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.793	0.207	0.000
H17 Corneal scars and opacities	0.792	0.208	0.000
J01 Acute sinusitis	0.791	0.209	0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.791	0.209	0.000
M07.36 Other psoriatic arthropathies (Lower leg)	0.790	0.210	0.000
H20.0 Acute and subacute iridocyclitis	0.790	0.210	0.000
M06.33 Rheumatoid nodule (Forearm)	0.789	0.211	0.000
M08 Juvenile arthritis	0.787	0.213	0.000
L02.0 Cutaneous abscess, furuncle and carbuncle of face	0.785	0.215	0.000
J15.0 Pneumonia due to Klebsiella pneumoniae	0.784	0.216	0.000
E14.5 With peripheral circulatory complications	0.781	0.219	0.000
M31.3 Wegener's granulomatosis	0.780	0.220	0.000
C73 Malignant neoplasm of thyroid gland	0.780	0.220	0.000
F33.4 Recurrent depressive disorder, currently in remission	0.777	0.223	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.777	0.223	0.000
L03.0 Cellulitis of finger and toe	0.776	0.224	0.000
M30.0 Polyarteritis nodosa	0.776	0.224	0.000
E11.5 With peripheral circulatory complications	0.776	0.224	0.000
M25.9 Joint disorder, unspecified	0.775	0.225	0.000
C82.4 Follicular lymphoma grade IIIb	0.774	0.226	0.000
L43 Lichen planus	0.774	0.226	0.000
C02 Malignant neoplasm of other and unspecified parts of tongue	0.774	0.226	0.000
M05.1 Rheumatoid lung disease	0.773	0.227	0.000
M25.8 Other specified joint disorders	0.773	0.227	0.000
F38 Other mood [affective] disorders	0.772	0.228	0.000
M31.4 Aortic arch syndrome [Takayasu]	0.771	0.228	0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.770	0.230	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.769	0.231	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.769	0.231	0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.767	0.233	0.000
J05 Acute obstructive laryngitis [croup] and epiglottitis	0.766	0.234	0.000
H40.3 Glaucoma secondary to eye trauma	0.766	0.234	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.763	0.237	0.000
M35.2 Behcet's disease	0.762	0.238	0.000
H54 Blindness and low vision	0.762	0.238	0.000
M34.8 Other forms of systemic sclerosis	0.761	0.239	0.000
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)	0.757	0.243	0.000
H31 Other disorders of choroid	0.755	0.244	0.000
H16 Keratitis	0.755	0.245	0.000
F60.7 Dependent personality disorder	0.755	0.245	0.000
C82.3 Follicular lymphoma grade IIIa	0.754	0.246	0.000
J80 Adult respiratory distress syndrome	0.754	0.246	0.000
M66.34 Spontaneous rupture of flexor tendons (Hand)	0.753	0.247	0.000
M46.1 Sacro-iliitis, not elsewhere classified	0.753	0.247	0.000
J15.1 Pneumonia due to Pseudomonas	0.753	0.247	0.000
M06.30 Rheumatoid nodule (Multiple sites)	0.752	0.248	0.000
C82.1 Mixed small cleaved and large cell, follicular	0.750	0.250	0.000
H30 Chorioretinal inflammation	0.749	0.251	0.000
M25.6 Stiffness of joint, not elsewhere classified	0.749	0.251	0.000
M31.8 Other specified necrotising vasculopathies	0.748	0.252	0.000
J95-J99 Other diseases of the respiratory system	0.747	0.253	0.000
H55-H59 Other disorders of eye and adnexa	0.746	0.254	0.000
E50-E64 Other nutritional deficiencies	0.746	0.254	0.000
M06.4 Inflammatory polyarthropathy	0.745	0.255	0.000
J46 Status asthmaticus	0.744	0.256	0.000
M14.6 Neuropathic arthropathy	0.744	0.256	0.000
M05.8 Other seropositive rheumatoid arthritis	0.744	0.256	0.000
H20.9 Iridocyclitis, unspecified	0.741	0.259	0.000
H21.5 Other adhesions and disruptions of iris and ciliary body	0.738	0.262	0.000
M31.1 Thrombotic microangiopathy	0.738	0.262	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.737	0.263	0.000
J42 Unspecified chronic bronchitis	0.735	0.265	0.000
M65.8 Other synovitis and tenosynovitis	0.734	0.265	0.000
M35.1 Other overlap syndromes	0.733	0.267	0.000
L43.9 Lichen planus, unspecified	0.733	0.267	0.000
E14.8 With unspecified complications	0.733	0.267	0.000
J17 Pneumonia in diseases classified elsewhere	0.733	0.267	0.000
K90.8 Other intestinal malabsorption	0.000	0.268	0.732
F00-F09 Organic, including symptomatic, mental disorders	0.730	0.270	0.000
E11.8 With unspecified complications	0.727	0.272	0.000
L01 Impetigo	0.727	0.273	0.000
J11.1 Influenza with other respiratory manifestations, virus not identified	0.727	0.273	0.000
M00.8 Arthritis and polyarthritis due to other specified bacterial agents	0.726	0.274	0.000
E14.2 Withrenal complications	0.725	0.275	0.000
J12 Viral pneumonia, not elsewhere classified	0.725	0.275	0.000
M24.2 Disorder of ligament	0.724	0.276	0.000
M62 Other disorders of muscle	0.722	0.278	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.721	0.279	0.000
F70-F79 Mental retardation	0.720	0.280	0.000
M00.92 Pyogenic arthritis, unspecified (Upper arm)	0.720	0.280	0.000
H54.4 Blindness, one eye	0.719	0.281	0.000
F33.0 Recurrent depressive disorder, current episode mild	0.718	0.281	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.717	0.283	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.717	0.283	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.717	0.283	0.000
E11.7 With multiple complications	0.717	0.283	0.000
M06.2 Rheumatoid bursitis	0.717	0.283	0.000
M06.1 Adult-onset Still's disease	0.717	0.283	0.000
E12 Malnutrition-related diabetes mellitus	0.717	0.283	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.717	0.283	0.000
M05.2 Rheumatoid vasculitis	0.717	0.283	0.000
M05.0 Felty's syndrome	0.717	0.283	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.717	0.283	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.717	0.283	0.000
E16.4 Abnormal secretion of gastrin	0.717	0.283	0.000
E16.3 Increased secretion of glucagon	0.717	0.283	0.000
E15 Nondiabetic hypoglycaemic coma	0.717	0.283	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.717	0.283	0.000
M35.8 Other specified systemic involvement of connective tissue	0.717	0.283	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.717	0.283	0.000
M35.5 Multifocal fibrosclerosis	0.717	0.283	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.717	0.283	0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.717	0.283	0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.717	0.283	0.000
M45.X6 Ankylosing spondylitis (Lumbar region)	0.717	0.283	0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.717	0.283	0.000
M45.X4 Ankylosing spondylitis (Thoracic region)	0.717	0.283	0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.717	0.283	0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.717	0.283	0.000
E14.7 With multiple complications	0.717	0.283	0.000
E14.0 With coma	0.717	0.283	0.000
M06.39 Rheumatoid nodule (Site unspecified)	0.716	0.284	0.000
M06.38 Rheumatoid nodule (Other)	0.716	0.284	0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.716	0.284	0.000
M06.31 Rheumatoid nodule (Shoulder region)	0.716	0.284	0.000
M49 Spondylopathies in diseases classified elsewhere	0.715	0.284	0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.715	0.284	0.000
C74 Malignant neoplasm of adrenal gland	0.715	0.285	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.714	0.285	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.714	0.285	0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.714	0.285	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.714	0.285	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.714	0.285	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.714	0.285	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.714	0.285	0.000
H36.8 Other retinal disorders in diseases classified elsewhere	0.714	0.286	0.000
M25.2 Flail joint	0.713	0.286	0.000
M25.1 Fistula of joint	0.713	0.286	0.000
H17.9 Corneal scar and opacity, unspecified	0.713	0.287	0.000
M65.2 Calcific tendinitis	0.713	0.287	0.000
M65.0 Abscess of tendon sheath	0.713	0.287	0.000
M25.49 Effusion of joint (Site unspecified)	0.713	0.287	0.000
M25.48 Effusion of joint (Other)	0.713	0.287	0.000
M25.41 Effusion of joint (Shoulder region)	0.713	0.287	0.000
J22 Unspecified acute lower respiratory infection	0.713	0.287	0.000
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)	0.712	0.288	0.000
M65.98 Synovitis and tenosynovitis, unspecified (Other)	0.712	0.288	0.000
H32 Chorioretinal disorders in diseases classified elsewhere	0.712	0.288	0.000
F32.8 Other depressive episodes	0.711	0.289	0.000
M20.0 Deformity of finger(s)	0.710	0.290	0.000
F29 Unspecified nonorganic psychosis	0.710	0.290	0.000
L60-L75 Disorders of skin appendages	0.709	0.291	0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.708	0.292	0.000
L00 Staphylococcal scalded skin syndrome	0.708	0.292	0.000
J82 Pulmonary eosinophilia, not elsewhere classified	0.707	0.293	0.000
L05 Pilonidal cyst	0.707	0.293	0.000
H40.4 Glaucoma secondary to eye inflammation	0.706	0.294	0.000
F80-F89 Disorders of psychological development	0.706	0.294	0.000
M14.2 Diabetic arthropathy	0.705	0.295	0.000
J10.1 Influenza with other respiratory manifestations, influenza virus identified	0.703	0.297	0.000
M91-M94 Chondropathies	0.703	0.297	0.000
M31.2 Lethal midline granuloma	0.702	0.298	0.000
M31.0 Hypersensitivity angiitis	0.702	0.298	0.000
C82.6 Cutaneous follicle centre lymphoma	0.701	0.299	0.000
C82.5 Diffuse follicle centre lymphoma	0.701	0.299	0.000
M00.91 Pyogenic arthritis, unspecified (Shoulder region)	0.699	0.301	0.000
F23 Acute and transient psychotic disorders	0.698	0.302	0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.696	0.304	0.000
J15.2 Pneumonia due to staphylococcus	0.695	0.305	0.000
M02 Reactive arthropathies	0.693	0.306	0.000
C09 Malignant neoplasm of tonsil	0.693	0.307	0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.693	0.307	0.000
C82.2 Large cell, follicular	0.693	0.307	0.000
F39 Unspecified mood [affective] disorder	0.692	0.307	0.000
M25.06 Haemarthrosis (Lower leg)	0.692	0.308	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.691	0.309	0.000
F60.8 Other specific personality disorders	0.691	0.309	0.000
J44 Other chronic obstructive pulmonary disease	0.691	0.309	0.000
M34.2 Systemic sclerosis induced by drugs and chemicals	0.688	0.312	0.000
M34.0 Progressive systemic sclerosis	0.688	0.312	0.000
Chapter VIII Diseases of the ear and mastoid process	0.688	0.312	0.000
F28 Other nonorganic psychotic disorders	0.686	0.314	0.000
F24 Induced delusional disorder	0.686	0.314	0.000
F21 Schizotypal disorder	0.686	0.314	0.000
M24.6 Ankylosis of joint	0.686	0.314	0.000
M24.54 Contracture of joint (Hand)	0.685	0.315	0.000
M66.24 Spontaneous rupture of extensor tendons (Hand)	0.684	0.315	0.000
M46.18 Sacroiliitis, not elsewhere classified-Sacral/sacrococ	0.684	0.316	0.000
J01.9 Acute sinusitis, unspecified	0.684	0.316	0.000
M65.14 Other infective (teno)synovitis (Hand)	0.683	0.317	0.000
J85 Abscess of lung and mediastinum	0.683	0.317	0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified	0.682	0.317	0.000
J09 Influenza due to certain identified influenza virus	0.682	0.317	0.000
J15.5 Pneumonia due to Escherichia coli	0.682	0.318	0.000
F00 Dementia in Alzheimer's disease	0.681	0.319	0.000
E16.1 Other hypoglycaemia	0.680	0.319	0.000
M60 Myositis	0.679	0.321	0.000
H21.4 Pupillary membranes	0.679	0.321	0.000
F20.5 Residual schizophrenia	0.678	0.322	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.678	0.322	0.000
F20.8 Other schizophrenia	0.676	0.324	0.000
F20.6 Simple schizophrenia	0.676	0.324	0.000
F20.4 Postschizophrenic depression	0.676	0.324	0.000
F20.3 Undifferentiated schizophrenia	0.676	0.324	0.000
F20.2 Catatonic schizophrenia	0.676	0.324	0.000
F20.1 Hebephrenic schizophrenia	0.676	0.324	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.676	0.324	0.000
C02.1 Border of tongue	0.675	0.324	0.000
M03 Postinfective and reactive arthropathies in diseases classified elsewhere	0.673	0.327	0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere	0.673	0.327	0.000
F68 Other disorders of adult personality and behaviour	0.673	0.327	0.000
F66 Psychological and behavioural disorders associated with sexual development and orientation	0.673	0.327	0.000
F65 Disorders of sexual preference	0.673	0.327	0.000
F63 Habit and impulse disorders	0.673	0.327	0.000
F62 Enduring personality changes, not attributable to brain damage and disease	0.673	0.327	0.000
F61 Mixed and other personality disorders	0.673	0.327	0.000
H42 Glaucoma in diseases classified elsewhere	0.673	0.327	0.000
C06 Malignant neoplasm of other and unspecified parts of mouth	0.673	0.327	0.000
K90.3 Pancreatic steatorrhoea	0.000	0.327	0.673
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.327	0.673
K90.1 Tropical sprue	0.000	0.327	0.673
M00.96 Pyogenic arthritis, unspecified (Lower leg)	0.673	0.327	0.000
J14 Pneumonia due to Haemophilus influenzae	0.672	0.328	0.000
M00.94 Pyogenic arthritis, unspecified (Hand)	0.672	0.328	0.000
M25.42 Effusion of joint (Upper arm)	0.672	0.328	0.000
H40.5 Glaucoma secondary to other eye disorders	0.672	0.328	0.000
H54.9 Unspecified visual impairment (binocular)	0.672	0.328	0.000
M07.6 Other enteropathic arthropathies	0.671	0.328	0.000
M07.5 Arthropathy in ulcerative colitis	0.671	0.328	0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.671	0.328	0.000
M07.2 Psoriatic spondylitis	0.671	0.328	0.000
M07.1 Arthritis mutilans	0.671	0.328	0.000
M07.0 Distal interphalangeal psoriatic arthropathy	0.671	0.328	0.000
J32.3 Chronic sphenoidal sinusitis	0.670	0.329	0.000
H15 Disorders of sclera	0.669	0.331	0.000
L08.1 Erythrasma	0.667	0.333	0.000
L08.0 Pyoderma	0.667	0.333	0.000
F60.6 Anxious [avoidant] personality disorder	0.667	0.333	0.000
J35.2 Hypertrophy of adenoids	0.665	0.335	0.000
M24.0 Loose body in joint	0.664	0.336	0.000
J15.7 Pneumonia due to Mycoplasma pneumoniae	0.663	0.337	0.000
H21.8 Other specified disorders of iris and ciliary body	0.662	0.338	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.661	0.339	0.000
M12.2 Villonodular synovitis (pigmented)	0.661	0.339	0.000
C02.4 Lingual tonsil	0.661	0.339	0.000
J02 Acute pharyngitis	0.661	0.339	0.000
H54.0 Blindness, both eyes	0.660	0.340	0.000
F34 Persistent mood [affective] disorders	0.660	0.340	0.000
J31.1 Chronic nasopharyngitis	0.660	0.340	0.000
E11.6 With other specified complications	0.659	0.340	0.000
Q24 Other congenital malformations of heart	0.659	0.341	0.000
J15.8 Other bacterial pneumonia	0.659	0.341	0.000
M30.8 Other conditions related to polyarteritis nodosa	0.658	0.342	0.000
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]	0.658	0.342	0.000
M30.2 Juvenile polyarteritis	0.658	0.342	0.000
E14.1 With ketoacidosis	0.657	0.342	0.000
M31.9 Necrotising vasculopathy, unspecified	0.657	0.343	0.000
H20.2 Lens-induced iridocyclitis	0.657	0.343	0.000
M66.36 Spontaneous rupture of flexor tendons (Lower leg)	0.657	0.343	0.000
F33.8 Other recurrent depressive disorders	0.657	0.343	0.000
F60.4 Histrionic personality disorder	0.657	0.343	0.000
F60.2 Dissocial personality disorder	0.657	0.343	0.000
F60.1 Schizoid personality disorder	0.657	0.343	0.000
F60.0 Paranoid personality disorder	0.657	0.343	0.000
J06.8 Other acute upper respiratory infections of multiple sites	0.656	0.344	0.000
J06.0 Acute laryngopharyngitis	0.656	0.344	0.000
M66.5 Spontaneous rupture of unspecified tendon	0.655	0.345	0.000
M66.1 Rupture of synovium	0.655	0.345	0.000
J11.0 Influenza with pneumonia, virus not identified	0.654	0.346	0.000
M24.56 Contracture of joint (Lower leg)	0.652	0.348	0.000
E40-E46 Malnutrition	0.651	0.349	0.000
C02.2 Ventral surface of tongue	0.651	0.349	0.000
F33.1 Recurrent depressive disorder, current episode moderate	0.650	0.350	0.000
M24.9 Joint derangement, unspecified	0.649	0.351	0.000
M25.83 Other specified joint disorders (Forearm)	0.649	0.351	0.000
F69 Unspecified disorder of adult personality and behaviour	0.649	0.351	0.000
F60.9 Personality disorder, unspecified	0.648	0.352	0.000
M00.90 Pyogenic arthritis, unspecified (Multiple sites)	0.647	0.352	0.000
L71 Rosacea	0.646	0.354	0.000
J41 Simple and mucopurulent chronic bronchitis	0.645	0.355	0.000
C03 Malignant neoplasm of gum	0.645	0.355	0.000
H40.6 Glaucoma secondary to drugs	0.644	0.356	0.000
J31.2 Chronic pharyngitis	0.643	0.356	0.000
J32.2 Chronic ethmoidal sinusitis	0.643	0.357	0.000
M24.7 Protrusio acetabuli	0.642	0.357	0.000
M25.99 Joint disorder, unspecified (Site unspecified)	0.642	0.358	0.000
L04.1 Acute lymphadenitis of trunk	0.642	0.358	0.000
J35.9 Chronic disease of tonsils and adenoids, unspecified	0.640	0.360	0.000
M00.2 Other streptococcal arthritis and polyarthritis	0.639	0.361	0.000
M00.1 Pneumococcal arthritis and polyarthritis	0.639	0.361	0.000
M00.0 Staphylococcal arthritis and polyarthritis	0.639	0.361	0.000
C10 Malignant neoplasm of oropharynx	0.639	0.361	0.000
M07.38 Other psoriatic arthropathies (Other)	0.639	0.361	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.639	0.361	0.000
M07.34 Other psoriatic arthropathies (Hand)	0.639	0.361	0.000
M07.33 Other psoriatic arthropathies (Forearm)	0.639	0.361	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.639	0.361	0.000
M07.31 Other psoriatic arthropathies (Shoulder region)	0.639	0.361	0.000
F25 Schizoaffective disorders	0.639	0.361	0.000
H40.8 Other glaucoma	0.638	0.362	0.000
F30 Manic episode	0.638	0.362	0.000
M13 Other arthritis	0.638	0.362	0.000
C02.9 Tongue, unspecified	0.636	0.364	0.000
H21.2 Degeneration of iris and ciliary body	0.636	0.364	0.000
E13 Other specified diabetes mellitus	0.636	0.364	0.000
F38.8 Other specified mood [affective] disorders	0.636	0.364	0.000
M25.64 Stiffness of joint, not elsewhere classified (Hand)	0.635	0.365	0.000
J95 Postprocedural respiratory disorders, not elsewhere classified	0.634	0.366	0.000
M08.0 Juvenile rheumatoid arthritis	0.634	0.366	0.000
H16.4 Corneal neovascularisation	0.634	0.366	0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.633	0.366	0.000
M11 Other crystal arthropathies	0.633	0.367	0.000
M65.86 Other synovitis and tenosynovitis (Lower leg)	0.633	0.367	0.000
M35.7 Hypermobility syndrome	0.633	0.367	0.000
M24.57 Contracture of joint (Ankle and foot)	0.633	0.367	0.000
E14.4 With neurological complications	0.632	0.367	0.000
J10.0 Influenza with pneumonia, influenza virus identified	0.632	0.368	0.000
J15.3 Pneumonia due to streptococcus, group B	0.631	0.368	0.000
H65-H75 Diseases of middle ear and mastoid	0.630	0.370	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations