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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs9275700
log Bayes Factor = 56.5748
Chromosome 6   position 32,688,055  (GRCh37) Explore rs9275700 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
G35 Multiple sclerosis
1.000 0.000 0.000
E10.3 With ophthalmic complications
0.999 0.001 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.999 0.001 0.000
E10.1 With ketoacidosis
0.997 0.003 0.000
G37 Other demyelinating diseases of central nervous system
0.992 0.008 0.000
E10-E14 Diabetes mellitus
0.987 0.013 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.975 0.017 0.008
G37.9 Demyelinating disease of central nervous system, unspecified
0.981 0.019 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.978 0.022 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.976 0.024 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.973 0.027 0.000
L60-L75 Disorders of skin appendages
0.971 0.029 0.000
L72.1 Trichilemmal cyst
0.969 0.031 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.968 0.032 0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.967 0.033 0.000
E10.5 With peripheral circulatory complications
0.961 0.039 0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.961 0.039 0.000
E10.4 With neurological complications
0.959 0.041 0.000
E14 Unspecified diabetes mellitus
0.955 0.045 0.000
L20-L30 Dermatitis and eczema
0.955 0.045 0.000
# Top node
0.955 0.045 0.000
Chapter VII Diseases of the eye and adnexa
0.950 0.050 0.000
Chapter VI Diseases of the nervous system
0.949 0.051 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.943 0.057 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.943 0.057 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.942 0.058 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.938 0.062 0.000
H00 Hordeolum and chalazion
0.935 0.065 0.000
E50-E64 Other nutritional deficiencies
0.931 0.069 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.925 0.075 0.000
E16 Other disorders of pancreatic internal secretion
0.921 0.079 0.000
H00.1 Chalazion
0.921 0.079 0.000
E16.2 Hypoglycaemia, unspecified
0.915 0.085 0.000
H36.0 Diabetic retinopathy
0.909 0.091 0.000
H36 Retinal disorders in diseases classified elsewhere
0.906 0.094 0.000
H30-H36 Disorders of choroid and retina
0.906 0.094 0.000
Q66 Congenital deformities of feet
0.900 0.100 0.000
L27 Dermatitis due to substances taken internally
0.900 0.100 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.899 0.101 0.000
E14.9 Without complications
0.891 0.109 0.000
H04 Disorders of lachrymal system
0.888 0.112 0.000
G37.8 Other specified demyelinating diseases of central nervous system
0.885 0.115 0.000
H17 Corneal scars and opacities
0.882 0.118 0.000
L71 Rosacea
0.880 0.120 0.000
E10.2 With renal complications
0.880 0.120 0.000
E03 Other hypothyroidism
0.007 0.123 0.869
E55 Vitamin D deficiency
0.873 0.127 0.000
L21 Seborrhoeic dermatitis
0.870 0.130 0.000
L04 Acute lymphadenitis
0.866 0.134 0.000
Chapter V Mental and behavioural disorders
0.856 0.144 0.000
Q66.8 Other congenital deformities of feet
0.856 0.144 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.855 0.145 0.000
L30 Other dermatitis
0.852 0.148 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.846 0.154 0.000
G63.2 Diabetic polyneuropathy
0.841 0.159 0.000
E55.9 Vitamin D deficiency, unspecified
0.831 0.169 0.000
L02.1 Cutaneous abscess, furuncle and carbuncle of neck
0.831 0.169 0.000
H00.0 Hordeolum and other deep inflammation of eyelid
0.831 0.169 0.000
L27.0 Generalised skin eruption due to drugs and medicaments
0.824 0.176 0.000
H17.9 Corneal scar and opacity, unspecified
0.819 0.181 0.000
H04.3 Acute and unspecified inflammation of lachrymal passages
0.817 0.183 0.000
H16 Keratitis
0.815 0.185 0.000
E14.6 With other specified complications
0.813 0.187 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.812 0.188 0.000
L21.9 Seborrhoeic dermatitis, unspecified
0.809 0.191 0.000
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites
0.807 0.193 0.000
H04.2 Epiphora
0.806 0.194 0.000
L70 Acne
0.806 0.194 0.000
H18 Other disorders of cornea
0.805 0.195 0.000
E14.3 With ophthalmic complications
0.804 0.196 0.000
H01 Other inflammation of eyelid
0.804 0.196 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.793 0.207 0.000
E10.8 With unspecified complications
0.790 0.209 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.787 0.213 0.000
H04.1 Other disorders of lachrymal gland
0.781 0.219 0.000
H20 Iridocyclitis
0.780 0.220 0.000
E53 Deficiency of other B group vitamins
0.779 0.221 0.000
F20 Schizophrenia
0.778 0.222 0.000
F03 Unspecified dementia
0.774 0.226 0.000
L30.8 Other specified dermatitis
0.768 0.232 0.000
L05 Pilonidal cyst
0.767 0.233 0.000
L72.8 Other follicular cysts of skin and subcutaneous tissue
0.767 0.233 0.000
Q74 Other congenital malformations of limb(s)
0.764 0.236 0.000
Q35-Q37 Cleft lip and cleft palate
0.761 0.239 0.000
L27.1 Localised skin eruption due to drugs and medicaments
0.761 0.239 0.000
L23 Allergic contact dermatitis
0.760 0.240 0.000
L65 Other nonscarring hair loss
0.759 0.241 0.000
L71.1 Rhinophyma
0.758 0.242 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.758 0.242 0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified
0.757 0.243 0.000
G36 Other acute disseminated demyelination
0.748 0.252 0.000
H16.0 Corneal ulcer
0.746 0.254 0.000
H18.6 Keratoconus
0.743 0.257 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.004 0.259 0.737
L01 Impetigo
0.739 0.261 0.000
E00-E07 Disorders of thyroid gland
0.040 0.262 0.698
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.738 0.262 0.000
E10.7 With multiple complications
0.737 0.263 0.000
F20.9 Schizophrenia, unspecified
0.735 0.265 0.000
E63 Other nutritional deficiencies
0.732 0.268 0.000
L63 Alopecia areata
0.730 0.269 0.000
H01.0 Blepharitis
0.730 0.270 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.729 0.271 0.000
E10.0 With coma
0.728 0.272 0.000
Q25 Congenital malformations of great arteries
0.724 0.276 0.000
Q21 Congenital malformations of cardiac septa
0.724 0.276 0.000
Q78 Other osteochondrodysplasias
0.723 0.277 0.000
Q24 Other congenital malformations of heart
0.723 0.277 0.000
H31 Other disorders of choroid
0.721 0.279 0.000
Q23 Congenital malformations of aortic and mitral valves
0.721 0.279 0.000
L71.9 Rosacea, unspecified
0.720 0.280 0.000
Q22 Congenital malformations of pulmonary and tricuspid valves
0.719 0.281 0.000
E03.8 Other specified hypothyroidism
0.003 0.282 0.714
F60-F69 Disorders of adult personality and behaviour
0.716 0.284 0.000
E10.6 With other specified complications
0.714 0.285 0.000
H15 Disorders of sclera
0.713 0.287 0.000
G37.5 Concentric sclerosis [Balo]
0.711 0.289 0.000
G37.4 Subacute necrotising myelitis
0.711 0.289 0.000
G37.2 Central pontine myelinolysis
0.711 0.289 0.000
G37.1 Central demyelination of corpus callosum
0.711 0.289 0.000
G37.0 Diffuse sclerosis
0.711 0.289 0.000
H17.8 Other corneal scars and opacities
0.710 0.290 0.000
Q65 Congenital deformities of hip
0.709 0.291 0.000
Q66.3 Other congenital varus deformities of feet
0.709 0.291 0.000
Q66.0 Talipes equinovarus
0.709 0.291 0.000
H04.8 Other disorders of lachrymal system
0.708 0.292 0.000
E12 Malnutrition-related diabetes mellitus
0.708 0.292 0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest
0.706 0.294 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.705 0.295 0.000
L20 Atopic dermatitis
0.704 0.296 0.000
F20.0 Paranoid schizophrenia
0.703 0.297 0.000
Q27 Other congenital malformations of peripheral vascular system
0.701 0.299 0.000
L04.2 Acute lymphadenitis of upper limb
0.701 0.299 0.000
L00 Staphylococcal scalded skin syndrome
0.700 0.300 0.000
E14.2 Withrenal complications
0.698 0.302 0.000
L04.8 Acute lymphadenitis of other sites
0.697 0.303 0.000
L75 Apocrine sweat disorders
0.696 0.303 0.000
L74 Eccrine sweat disorders
0.696 0.303 0.000
L67 Hair colour and hair shaft abnormalities
0.696 0.303 0.000
L64 Androgenic alopecia
0.696 0.303 0.000
L62 Nail disorders in diseases classified elsewhere
0.696 0.303 0.000
E14.5 With peripheral circulatory complications
0.696 0.304 0.000
F23 Acute and transient psychotic disorders
0.696 0.304 0.000
E14.8 With unspecified complications
0.695 0.305 0.000
L72.2 Steatocystoma multiplex
0.694 0.306 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.694 0.306 0.000
G30-G32 Other degenerative diseases of the nervous system
0.686 0.314 0.000
E14.7 With multiple complications
0.685 0.315 0.000
E14.1 With ketoacidosis
0.685 0.315 0.000
E14.0 With coma
0.685 0.315 0.000
L24 Irritant contact dermatitis
0.685 0.315 0.000
L26 Exfoliative dermatitis
0.685 0.315 0.000
L22 Diaper [napkin] dermatitis
0.685 0.315 0.000
Q28 Other congenital malformations of circulatory system
0.685 0.315 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.684 0.315 0.000
L30.1 Dyshidrosis [pompholyx]
0.682 0.318 0.000
F00 Dementia in Alzheimer's disease
0.681 0.319 0.000
H19.1 Herpesviral keratitis and keratoconjunctivitis
0.678 0.322 0.000
Q66.6 Other congenital valgus deformities of feet
0.677 0.323 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.676 0.323 0.000
E15 Nondiabetic hypoglycaemic coma
0.676 0.324 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.676 0.324 0.000
L25 Unspecified contact dermatitis
0.675 0.325 0.000
L66 Cicatricial alopecia [scarring hair loss]
0.674 0.326 0.000
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock
0.673 0.327 0.000
L04.1 Acute lymphadenitis of trunk
0.672 0.328 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.672 0.328 0.000
L71.8 Other rosacea
0.672 0.328 0.000
Q66.7 Pes cavus
0.668 0.332 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.667 0.332 0.000
E56 Other vitamin deficiencies
0.667 0.332 0.000
E51 Thiamine deficiency
0.667 0.332 0.000
E50 Vitamin A deficiency
0.667 0.332 0.000
E60 Dietary zinc deficiency
0.667 0.332 0.000
E59 Dietary selenium deficiency
0.667 0.332 0.000
E54 Ascorbic acid deficiency
0.667 0.332 0.000
E52 Niacin deficiency [pellagra]
0.667 0.332 0.000
Q66.2 Metatarsus varus
0.667 0.333 0.000
Q79.6 Ehlers-Danlos syndrome
0.667 0.333 0.000
Q74.0 Other congenital malformations of upper limb(s), including shoulder girdle
0.665 0.335 0.000
E40-E46 Malnutrition
0.664 0.335 0.000
E53.9 Vitamin B deficiency, unspecified
0.664 0.336 0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine
0.663 0.336 0.000
Q75 Other congenital malformations of skull and face bones
0.663 0.336 0.000
Q73 Reduction defects of unspecified limb
0.663 0.336 0.000
Q72 Reduction defects of lower limb
0.663 0.336 0.000
Q71 Reduction defects of upper limb
0.663 0.336 0.000
Q70 Syndactyly
0.663 0.336 0.000
Q69 Polydactyly
0.663 0.336 0.000
Q68 Other congenital musculoskeletal deformities
0.663 0.336 0.000
L04.0 Acute lymphadenitis of face, head and neck
0.663 0.337 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.661 0.339 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.661 0.339 0.000
E16.4 Abnormal secretion of gastrin
0.661 0.339 0.000
E16.3 Increased secretion of glucagon
0.661 0.339 0.000
F01 Vascular dementia
0.660 0.340 0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.657 0.342 0.000
E06 Thyroiditis
0.021 0.343 0.636
E05 Thyrotoxicosis [hyperthyroidism]
0.009 0.343 0.648
L27.2 Dermatitis due to ingested food
0.654 0.346 0.000
L40-L45 Papulosquamous disorders
0.079 0.349 0.572
H36.8 Other retinal disorders in diseases classified elsewhere
0.650 0.350 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.649 0.351 0.000
E61 Deficiency of other nutrient elements
0.648 0.352 0.000
H20.9 Iridocyclitis, unspecified
0.647 0.353 0.000
L70.9 Acne, unspecified
0.647 0.353 0.000
L02.0 Cutaneous abscess, furuncle and carbuncle of face
0.646 0.353 0.000
L68 Hypertrichosis
0.645 0.354 0.000
Q66.9 Congenital deformity of feet, unspecified
0.645 0.355 0.000
Q66.5 Congenital pes planus
0.645 0.355 0.000
Q66.4 Talipes calcaneovalgus
0.645 0.355 0.000
Q66.1 Talipes calcaneovarus
0.645 0.355 0.000
L27.9 Dermatitis due to unspecified substance taken internally
0.645 0.355 0.000
L27.8 Dermatitis due to other substances taken internally
0.645 0.355 0.000
Q26 Congenital malformations of great veins
0.645 0.355 0.000
Q20 Congenital malformations of cardiac chambers and connexions
0.645 0.355 0.000
E58 Dietary calcium deficiency
0.641 0.358 0.000
Q17 Other congenital malformations of ear
0.640 0.360 0.000
L08 Other local infections of skin and subcutaneous tissue
0.638 0.362 0.000
L70.0 Acne vulgaris
0.637 0.363 0.000
H04.0 Dacryoadenitis
0.636 0.363 0.000
H18.9 Disorder of cornea, unspecified
0.636 0.364 0.000
Q35 Cleft palate
0.634 0.366 0.000
F60 Specific personality disorders
0.633 0.367 0.000
H17.1 Other central corneal opacity
0.632 0.367 0.000
H17.0 Adherent leukoma
0.632 0.367 0.000
L71.0 Perioral dermatitis
0.631 0.369 0.000
H21 Other disorders of iris and ciliary body
0.630 0.370 0.000
E03.5 Myxoedema coma
0.005 0.371 0.623
E03.4 Atrophy of thyroid (acquired)
0.005 0.371 0.623
E03.3 Postinfectious hypothyroidism
0.005 0.371 0.623
L05.0 Pilonidal cyst with abscess
0.628 0.372 0.000
H20.8 Other iridocyclitis
0.627 0.373 0.000
E55.0 Rickets, active
0.626 0.374 0.000
L72.0 Epidermal cyst
0.625 0.375 0.000
L21.8 Other seborrhoeic dermatitis
0.624 0.376 0.000
L21.1 Seborrhoeic infantile dermatitis
0.624 0.376 0.000
L21.0 Seborrhoea capitis
0.624 0.376 0.000
F00.9 Dementia in Alzheimer's disease, unspecified
0.623 0.377 0.000
L04.3 Acute lymphadenitis of lower limb
0.621 0.379 0.000
G70-G73 Diseases of myoneural junction and muscle
0.620 0.380 0.000
H18.4 Corneal degeneration
0.618 0.382 0.000
H30 Chorioretinal inflammation
0.615 0.385 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.001 0.385 0.614
E06.3 Autoimmune thyroiditis
0.003 0.386 0.611
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.614 0.386 0.000
G64 Other disorders of peripheral nervous system
0.613 0.387 0.000
F70-F79 Mental retardation
0.613 0.387 0.000
L23.1 Allergic contact dermatitis due to adhesives
0.613 0.387 0.000
Q21.0 Ventricular septal defect
0.613 0.387 0.000
L30.5 Pityriasis alba
0.611 0.389 0.000
L30.3 Infective dermatitis
0.611 0.389 0.000
L30.2 Cutaneous autosensitisation
0.611 0.389 0.000
L30.0 Nummular dermatitis
0.611 0.389 0.000
F80-F89 Disorders of psychological development
0.610 0.390 0.000
L65.9 Nonscarring hair loss, unspecified
0.607 0.393 0.000
G63.8 Polyneuropathy in other diseases classified elsewhere
0.607 0.393 0.000
G63.6 Polyneuropathy in other musculoskeletal disorders
0.607 0.393 0.000
G63.5 Polyneuropathy in systemic connective tissue disorders
0.607 0.393 0.000
G63.4 Polyneuropathy in nutritional deficiency
0.607 0.393 0.000
G63.3 Polyneuropathy in other endocrine and metabolic diseases
0.607 0.393 0.000
G63.1 Polyneuropathy in neoplastic disease
0.607 0.393 0.000
G63.0 Polyneuropathy in infectious and parasitic diseases classified elsewhere
0.607 0.393 0.000
H16.8 Other keratitis
0.606 0.394 0.000
F20.8 Other schizophrenia
0.606 0.394 0.000
H55-H59 Other disorders of eye and adnexa
0.604 0.396 0.000
L04.9 Acute lymphadenitis, unspecified
0.604 0.396 0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos
0.602 0.398 0.000
H18.2 Other corneal oedema
0.600 0.399 0.000
H01.1 Non-infectious dermatoses of eyelid
0.600 0.400 0.000
F23.9 Acute and transient psychotic disorder, unspecified
0.599 0.401 0.000
Q25.0 Patent ductus arteriosus
0.597 0.403 0.000
L43 Lichen planus
0.024 0.405 0.571
L23.9 Allergic contact dermatitis, unspecified cause
0.595 0.405 0.000
Q22.5 Ebstein's anomaly
0.593 0.407 0.000
Q23.1 Congenital insufficiency of aortic valve
0.593 0.407 0.000
H16.1 Other superficial keratitis without conjunctivitis
0.592 0.408 0.000
L30.9 Dermatitis, unspecified
0.590 0.410 0.000
Q21.8 Other congenital malformations of cardiac septa
0.590 0.410 0.000
Q24.9 Congenital malformation of the heart, unspecified
0.589 0.411 0.000
H18.1 Bullous keratopathy
0.589 0.411 0.000
E63.9 Nutritional deficiency, unspecified
0.589 0.411 0.000
H31.0 Chorioretinal scars
0.588 0.412 0.000
E14.4 With neurological complications
0.587 0.413 0.000
H16.4 Corneal neovascularisation
0.587 0.413 0.000
Chapter XXII Codes for special purposes
0.586 0.414 0.000
L40 Psoriasis
0.006 0.414 0.580
H31.8 Other specified disorders of choroid
0.585 0.415 0.000
H16.3 Interstitial and deep keratitis
0.584 0.416 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.583 0.417 0.000
H04.6 Other changes in lachrymal passages
0.582 0.417 0.000
F09 Unspecified organic or symptomatic mental disorder
0.582 0.418 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.582 0.418 0.000
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit
0.581 0.419 0.000
Q96 Turner's syndrome
0.580 0.420 0.000
Q25.1 Coarctation of aorta
0.580 0.420 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.579 0.420 0.000
Q31 Congenital malformations of larynx
0.579 0.420 0.000
Q78.0 Osteogenesis imperfecta
0.579 0.421 0.000
L70.8 Other acne
0.578 0.422 0.000
L70.5 Acne excoriee des jeunes filles
0.578 0.422 0.000
L70.4 Infantile acne
0.578 0.422 0.000
L70.3 Acne tropica
0.578 0.422 0.000
L70.2 Acne varioliformis
0.578 0.422 0.000
L70.1 Acne conglobata
0.578 0.422 0.000
H18.7 Other corneal deformities
0.577 0.423 0.000
H18.3 Changes in corneal membranes
0.577 0.423 0.000
H18.0 Corneal pigmentations and deposits
0.577 0.423 0.000
H53-H54 Visual disturbances and blindness
0.576 0.424 0.000
L30.4 Erythema intertrigo
0.573 0.427 0.000
Q67.6 Pectus excavatum
0.573 0.427 0.000
Q24.5 Malformation of coronary vessels
0.572 0.428 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.571 0.429 0.000
H01.8 Other specified inflammation of eyelid
0.570 0.430 0.000
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified
0.570 0.430 0.000
H04.9 Disorder of lachrymal system, unspecified
0.570 0.430 0.000
L43.9 Lichen planus, unspecified
0.001 0.430 0.569
F28 Other nonorganic psychotic disorders
0.569 0.431 0.000
F24 Induced delusional disorder
0.569 0.431 0.000
F21 Schizotypal disorder
0.569 0.431 0.000
L01.0 Impetigo [any organism] [any site]
0.568 0.431 0.000
G36.0 Neuromyelitis optica [Devic]
0.568 0.432 0.000
H15.0 Scleritis
0.568 0.432 0.000
E53.8 Deficiency of other specified B group vitamins
0.568 0.432 0.000
L40.5 Arthropathic psoriasis
0.000 0.432 0.568
G80-G83 Cerebral palsy and other paralytic syndromes
0.568 0.432 0.000
H03.8 Involvement of eyelid in other diseases classified elsewhere
0.567 0.433 0.000
H19.8 Other disorders of sclera and cornea in diseases classified elsewhere
0.564 0.436 0.000
H19.2 Keratitis and keratoconjunctivitis in other infectious and parasitic diseases classified elsewhere
0.564 0.436 0.000
H19.0 Scleritis and episcleritis in diseases classified elsewhere
0.564 0.436 0.000
L40.9 Psoriasis, unspecified
0.000 0.438 0.562
L10-L14 Bullous disorders
0.554 0.440 0.006
H20.2 Lens-induced iridocyclitis
0.559 0.441 0.000
H20.1 Chronic iridocyclitis
0.559 0.441 0.000
E53.1 Pyridoxine deficiency
0.558 0.442 0.000
E53.0 Riboflavin deficiency
0.558 0.442 0.000
H19.3 Keratitis and keratoconjunctivitis in other diseases classified elsewhere
0.558 0.442 0.000
L63.9 Alopecia areata, unspecified
0.558 0.442 0.000
F20.6 Simple schizophrenia
0.558 0.442 0.000
F20.4 Postschizophrenic depression
0.558 0.442 0.000
F20.3 Undifferentiated schizophrenia
0.558 0.442 0.000
F20.2 Catatonic schizophrenia
0.558 0.442 0.000
F20.1 Hebephrenic schizophrenia
0.558 0.442 0.000
Q27.3 Peripheral arteriovenous malformation
0.556 0.443 0.000
Q17.5 Prominent ear
0.556 0.444 0.000
Q74.2 Other congenital malformations of lower limb(s), including pelvic girdle
0.555 0.444 0.000
F20.5 Residual schizophrenia
0.555 0.445 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.006 0.445 0.549
H46-H48 Disorders of optic nerve and visual pathways
0.554 0.445 0.000
Q65.8 Other congenital deformities of hip
0.554 0.446 0.000
Chapter XX External causes of morbidity and mortality
0.554 0.446 0.000
F23.0 Acute polymorphic psychotic disorder without symptoms of schizophrenia
0.554 0.446 0.000
F07.0 Organic personality disorder
0.553 0.447 0.000
L08.8 Other specified local infections of skin and subcutaneous tissue
0.552 0.448 0.000
G01 Meningitis in bacterial diseases classified elsewhere
0.552 0.448 0.000
F01.9 Vascular dementia, unspecified
0.552 0.448 0.000
E03.1 Congenital hypothyroidism without goitre
0.006 0.449 0.545
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified
0.550 0.450 0.000
H16.9 Keratitis, unspecified
0.549 0.450 0.000
F50 Eating disorders
0.549 0.451 0.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.451 0.549
F60.3 Emotionally unstable personality disorder
0.549 0.451 0.000
Q74.9 Unspecified congenital malformation of limb(s)
0.548 0.452 0.000
Q74.8 Other specified congenital malformations of limb(s)
0.548 0.452 0.000
Q74.3 Arthrogryposis multiplex congenita
0.548 0.452 0.000
Q21.9 Congenital malformation of cardiac septum, unspecified
0.547 0.452 0.000
Q67.4 Other congenital deformities of skull, face and jaw
0.546 0.454 0.000
Q37 Cleft palate with cleft lip
0.545 0.454 0.000
Q36 Cleft lip
0.545 0.454 0.000
L23.8 Allergic contact dermatitis due to other agents
0.545 0.455 0.000
L23.7 Allergic contact dermatitis due to plants, except food
0.545 0.455 0.000
L23.6 Allergic contact dermatitis due to food in contact with the skin
0.545 0.455 0.000
L23.4 Allergic contact dermatitis due to dyes
0.545 0.455 0.000
L23.3 Allergic contact dermatitis due to drugs in contact with the skin
0.545 0.455 0.000
L23.2 Allergic contact dermatitis due to cosmetics
0.545 0.455 0.000
L23.0 Allergic contact dermatitis due to metals
0.545 0.455 0.000
L65.8 Other specified nonscarring hair loss
0.544 0.455 0.000
L65.2 Alopecia mucinosa
0.544 0.455 0.000
L65.1 Anagen effluvium
0.544 0.455 0.000
L65.0 Telogen effluvium
0.544 0.455 0.000
Q35.9 Cleft palate, unspecified
0.544 0.456 0.000
Q16 Congenital malformations of ear causing impairment of hearing
0.543 0.457 0.000
Q15 Other congenital malformations of eye
0.543 0.457 0.000
Q13 Congenital malformations of anterior segment of eye
0.543 0.457 0.000
Q79.9 Congenital malformation of musculoskeletal system, unspecified
0.543 0.457 0.000
Q79.5 Other congenital malformations of abdominal wall
0.543 0.457 0.000
Q79.4 Prune belly syndrome
0.543 0.457 0.000
Q79.3 Gastroschisis
0.543 0.457 0.000
Q79.2 Exomphalos
0.543 0.457 0.000
Q79.1 Other congenital malformations of diaphragm
0.543 0.457 0.000
Q79.0 Congenital diaphragmatic hernia
0.543 0.457 0.000
Q28.2 Arteriovenous malformation of cerebral vessels
0.543 0.457 0.000
F99-F99 Unspecified mental disorder
0.541 0.459 0.000
Q21.3 Tetralogy of Fallot
0.540 0.460 0.000
G36.9 Acute disseminated demyelination, unspecified
0.536 0.464 0.000
G36.8 Other specified acute disseminated demyelination
0.536 0.464 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.536 0.464 0.000
H21.1 Other vascular disorders of iris and ciliary body
0.535 0.465 0.000
L05.9 Pilonidal cyst without abscess
0.534 0.466 0.000
G30 Alzheimer's disease
0.530 0.470 0.000
L01.1 Impetiginisation of other dermatoses
0.530 0.470 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.029 0.471 0.501
E00 Congenital iodine-deficiency syndrome
0.029 0.471 0.501
Q99 Other chromosome abnormalities, not elsewhere classified
0.529 0.471 0.000
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified
0.529 0.471 0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified
0.529 0.471 0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified
0.529 0.471 0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified
0.529 0.471 0.000
Q91 Edwards' syndrome and Patau's syndrome
0.529 0.471 0.000
Q90 Down's syndrome
0.529 0.471 0.000
Q14 Congenital malformations of posterior segment of eye
0.529 0.471 0.000
H05 Disorders of orbit
0.529 0.471 0.000
L20.8 Other atopic dermatitis
0.527 0.473 0.000
G70 Myasthenia gravis and other myoneural disorders
0.527 0.473 0.000
E63.8 Other specified nutritional deficiencies
0.524 0.475 0.000
E63.1 Imbalance of constituents of food intake
0.524 0.475 0.000
E63.0 Essential fatty acid [EFA] deficiency
0.524 0.475 0.000
L63.8 Other alopecia areata
0.524 0.476 0.000
L63.2 Ophiasis
0.524 0.476 0.000
L63.1 Alopecia universalis
0.524 0.476 0.000
L63.0 Alopecia (capitis) totalis
0.524 0.476 0.000
Q34 Other congenital malformations of respiratory system
0.523 0.477 0.000
Q33 Congenital malformations of lung
0.523 0.477 0.000
Q32 Congenital malformations of trachea and bronchus
0.523 0.477 0.000
Q30 Congenital malformations of nose
0.523 0.477 0.000
F51 Nonorganic sleep disorders
0.522 0.478 0.000
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified
0.521 0.479 0.000
W00-W19 Falls
0.521 0.479 0.000
Q25.9 Congenital malformation of great arteries, unspecified
0.519 0.480 0.000
Q25.8 Other congenital malformations of great arteries
0.519 0.480 0.000
Q25.7 Other congenital malformations of pulmonary artery
0.519 0.480 0.000
Q25.5 Atresia of pulmonary artery
0.519 0.480 0.000
Q25.3 Stenosis of aorta
0.519 0.480 0.000
Q25.2 Atresia of aorta
0.519 0.480 0.000
Q21.4 Aortopulmonary septal defect
0.519 0.481 0.000
Q21.2 Atrioventricular septal defect
0.519 0.481 0.000
Q78.9 Osteochondrodysplasia, unspecified
0.519 0.481 0.000
Q78.8 Other specified osteochondrodysplasias
0.519 0.481 0.000
Q78.6 Multiple congenital exostoses
0.519 0.481 0.000
Q78.5 Metaphyseal dysplasia
0.519 0.481 0.000
Q78.4 Enchondromatosis
0.519 0.481 0.000
Q78.3 Progressive diaphyseal dysplasia
0.519 0.481 0.000
Q78.2 Osteopetrosis
0.519 0.481 0.000
Q78.1 Polyostotic fibrous dysplasia
0.519 0.481 0.000
Q24.6 Congenital heart block
0.518 0.481 0.000
Q24.4 Congenital subaortic stenosis
0.518 0.481 0.000
Q24.3 Pulmonary infundibular stenosis
0.518 0.481 0.000
Q24.2 Cor triatriatum
0.518 0.481 0.000
Q24.1 Levocardia
0.518 0.481 0.000
Q23.0 Congenital stenosis of aortic valve
0.517 0.483 0.000
H31.9 Disorder of choroid, unspecified
0.517 0.483 0.000
H31.4 Choroidal detachment
0.517 0.483 0.000
H31.2 Hereditary choroidal dystrophy
0.517 0.483 0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified
0.517 0.483 0.000
Q23.8 Other congenital malformations of aortic and mitral valves
0.517 0.483 0.000
Q23.4 Hypoplastic left heart syndrome
0.517 0.483 0.000
Q23.3 Congenital mitral insufficiency
0.517 0.483 0.000
Q23.2 Congenital mitral stenosis
0.517 0.483 0.000
E83.1 Disorders of iron metabolism
0.517 0.483 0.000
F60.7 Dependent personality disorder
0.516 0.483 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.516 0.484 0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere
0.516 0.484 0.000
Q22.9 Congenital malformation of tricuspid valve, unspecified
0.515 0.485 0.000
Q22.8 Other congenital malformations of tricuspid valve
0.515 0.485 0.000
Q22.6 Hypoplastic right heart syndrome
0.515 0.485 0.000
Q22.4 Congenital tricuspid stenosis
0.515 0.485 0.000
Q22.3 Other congenital malformations of pulmonary valve
0.515 0.485 0.000
Q22.2 Congenital pulmonary valve insufficiency
0.515 0.485 0.000
Q22.0 Pulmonary valve atresia
0.515 0.485 0.000
H22.1 Iridocyclitis in other diseases classified elsewhere
0.515 0.485 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.371 0.486 0.143
F68 Other disorders of adult personality and behaviour
0.514 0.486 0.000
F66 Psychological and behavioural disorders associated with sexual development and orientation
0.514 0.486 0.000
F65 Disorders of sexual preference
0.514 0.486 0.000
F63 Habit and impulse disorders
0.514 0.486 0.000
F62 Enduring personality changes, not attributable to brain damage and disease
0.514 0.486 0.000
F61 Mixed and other personality disorders
0.514 0.486 0.000
H15.9 Disorder of sclera, unspecified
0.511 0.488 0.000
H15.8 Other disorders of sclera
0.511 0.488 0.000
E13 Other specified diabetes mellitus
0.511 0.489 0.000
F07.2 Postconcussional syndrome
0.511 0.489 0.000
Q24.0 Dextrocardia
0.509 0.491 0.000
Q65.9 Congenital deformity of hip, unspecified
0.508 0.491 0.000
Q65.6 Unstable hip
0.508 0.491 0.000
Q65.5 Congenital subluxation of hip, unspecified
0.508 0.491 0.000
Q65.4 Congenital subluxation of hip, bilateral
0.508 0.491 0.000
Q65.3 Congenital subluxation of hip, unilateral
0.508 0.491 0.000
Q65.2 Congenital dislocation of hip, unspecified
0.508 0.491 0.000
Q65.1 Congenital dislocation of hip, bilateral
0.508 0.491 0.000
Q65.0 Congenital dislocation of hip, unilateral
0.508 0.491 0.000
Q22.1 Congenital pulmonary valve stenosis
0.508 0.491 0.000
L50-L54 Urticaria and erythema
0.504 0.492 0.004
F55 Abuse of non-dependence-producing substances
0.508 0.492 0.000
E12.9 Without complications
0.507 0.492 0.000
E12.8 With unspecified complications
0.507 0.492 0.000
E12.7 With multiple complications
0.507 0.492 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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