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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs9276147
log Bayes Factor = 53.958
Chromosome 6   position 32,698,098  (GRCh37) Explore rs9276147 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
G35 Multiple sclerosis
1.000 0.000 0.000
E10.3 With ophthalmic complications
0.999 0.001 0.000
E10.1 With ketoacidosis
0.995 0.005 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.995 0.005 0.000
G37 Other demyelinating diseases of central nervous system
0.991 0.009 0.000
G37.9 Demyelinating disease of central nervous system, unspecified
0.985 0.015 0.000
E10.5 With peripheral circulatory complications
0.952 0.048 0.000
E10.4 With neurological complications
0.927 0.073 0.000
E10-E14 Diabetes mellitus
0.926 0.074 0.000
E03 Other hypothyroidism
0.004 0.098 0.897
E14 Unspecified diabetes mellitus
0.895 0.105 0.000
G37.8 Other specified demyelinating diseases of central nervous system
0.886 0.114 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.880 0.120 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.829 0.127 0.045
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.871 0.129 0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.867 0.133 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.861 0.139 0.001
E14.9 Without complications
0.851 0.149 0.000
E10.2 With renal complications
0.846 0.154 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.844 0.155 0.001
L72.1 Trichilemmal cyst
0.830 0.170 0.000
L60-L75 Disorders of skin appendages
0.821 0.177 0.002
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.821 0.178 0.001
L72 Follicular cysts of skin and subcutaneous tissue
0.818 0.182 0.000
E50-E64 Other nutritional deficiencies
0.812 0.188 0.000
L20-L30 Dermatitis and eczema
0.807 0.191 0.002
E16 Other disorders of pancreatic internal secretion
0.805 0.195 0.000
E16.2 Hypoglycaemia, unspecified
0.800 0.200 0.000
E00-E07 Disorders of thyroid gland
0.024 0.216 0.761
L04 Acute lymphadenitis
0.777 0.223 0.000
L02.1 Cutaneous abscess, furuncle and carbuncle of neck
0.770 0.230 0.000
E55 Vitamin D deficiency
0.767 0.233 0.000
L27 Dermatitis due to substances taken internally
0.766 0.233 0.001
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.002 0.238 0.760
E10.8 With unspecified complications
0.754 0.245 0.000
G36 Other acute disseminated demyelination
0.746 0.254 0.000
E03.8 Other specified hypothyroidism
0.002 0.254 0.744
E14.3 With ophthalmic complications
0.739 0.261 0.000
E55.9 Vitamin D deficiency, unspecified
0.736 0.264 0.000
E14.6 With other specified complications
0.734 0.266 0.000
E10.6 With other specified complications
0.732 0.268 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.005 0.270 0.725
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites
0.727 0.272 0.000
L05 Pilonidal cyst
0.724 0.276 0.000
L27.0 Generalised skin eruption due to drugs and medicaments
0.724 0.276 0.000
L71 Rosacea
0.723 0.276 0.001
E10.7 With multiple complications
0.723 0.277 0.000
L21 Seborrhoeic dermatitis
0.720 0.279 0.001
G37.5 Concentric sclerosis [Balo]
0.711 0.289 0.000
G37.4 Subacute necrotising myelitis
0.711 0.289 0.000
G37.2 Central pontine myelinolysis
0.711 0.289 0.000
G37.1 Central demyelination of corpus callosum
0.711 0.289 0.000
G37.0 Diffuse sclerosis
0.711 0.289 0.000
L30 Other dermatitis
0.706 0.294 0.000
E06 Thyroiditis
0.012 0.295 0.693
E10.0 With coma
0.703 0.296 0.000
# Top node
0.699 0.301 0.000
Chapter VII Diseases of the eye and adnexa
0.697 0.303 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.693 0.307 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.691 0.309 0.000
Chapter VI Diseases of the nervous system
0.691 0.309 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.309 0.690
H00 Hordeolum and chalazion
0.685 0.315 0.000
H36.0 Diabetic retinopathy
0.684 0.316 0.000
H00.1 Chalazion
0.676 0.324 0.000
H36 Retinal disorders in diseases classified elsewhere
0.674 0.326 0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.672 0.328 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.671 0.329 0.000
E14.2 Withrenal complications
0.667 0.333 0.000
E06.3 Autoimmune thyroiditis
0.002 0.333 0.665
H30-H36 Disorders of choroid and retina
0.667 0.333 0.000
E12 Malnutrition-related diabetes mellitus
0.664 0.336 0.000
L01 Impetigo
0.662 0.338 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.659 0.341 0.000
L21.9 Seborrhoeic dermatitis, unspecified
0.657 0.342 0.000
L70 Acne
0.656 0.343 0.001
H04 Disorders of lachrymal system
0.655 0.345 0.000
E14.8 With unspecified complications
0.653 0.346 0.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.348 0.652
E03.5 Myxoedema coma
0.003 0.354 0.643
E03.4 Atrophy of thyroid (acquired)
0.003 0.354 0.643
E03.3 Postinfectious hypothyroidism
0.003 0.354 0.643
L23 Allergic contact dermatitis
0.645 0.354 0.001
L30.8 Other specified dermatitis
0.645 0.355 0.000
H17 Corneal scars and opacities
0.643 0.357 0.000
E14.7 With multiple complications
0.642 0.358 0.000
E14.1 With ketoacidosis
0.642 0.358 0.000
E14.0 With coma
0.642 0.358 0.000
E63 Other nutritional deficiencies
0.638 0.362 0.000
Q66 Congenital deformities of feet
0.638 0.362 0.000
E61 Deficiency of other nutrient elements
0.630 0.370 0.000
L04.2 Acute lymphadenitis of upper limb
0.630 0.370 0.000
L65 Other nonscarring hair loss
0.628 0.371 0.001
Q20-Q28 Congenital malformations of the circulatory system
0.628 0.372 0.000
L72.8 Other follicular cysts of skin and subcutaneous tissue
0.627 0.373 0.000
L04.0 Acute lymphadenitis of face, head and neck
0.627 0.373 0.000
L04.8 Acute lymphadenitis of other sites
0.625 0.374 0.000
E53 Deficiency of other B group vitamins
0.625 0.375 0.000
L05.0 Pilonidal cyst with abscess
0.622 0.378 0.000
L63 Alopecia areata
0.618 0.381 0.002
Chapter V Mental and behavioural disorders
0.618 0.382 0.000
L00 Staphylococcal scalded skin syndrome
0.617 0.382 0.001
L27.1 Localised skin eruption due to drugs and medicaments
0.609 0.391 0.000
E40-E46 Malnutrition
0.607 0.393 0.001
L71.1 Rhinophyma
0.603 0.396 0.000
L04.1 Acute lymphadenitis of trunk
0.603 0.396 0.000
E14.5 With peripheral circulatory complications
0.602 0.398 0.000
Q66.8 Other congenital deformities of feet
0.599 0.401 0.000
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock
0.599 0.401 0.000
L02.0 Cutaneous abscess, furuncle and carbuncle of face
0.599 0.401 0.000
L20 Atopic dermatitis
0.597 0.402 0.001
H18 Other disorders of cornea
0.598 0.402 0.000
H04.3 Acute and unspecified inflammation of lachrymal passages
0.597 0.403 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.593 0.407 0.000
H17.9 Corneal scar and opacity, unspecified
0.591 0.409 0.000
L75 Apocrine sweat disorders
0.589 0.410 0.002
L74 Eccrine sweat disorders
0.589 0.410 0.002
L67 Hair colour and hair shaft abnormalities
0.589 0.410 0.002
L64 Androgenic alopecia
0.589 0.410 0.002
L62 Nail disorders in diseases classified elsewhere
0.589 0.410 0.002
H04.1 Other disorders of lachrymal gland
0.589 0.411 0.000
E15 Nondiabetic hypoglycaemic coma
0.589 0.411 0.001
L72.2 Steatocystoma multiplex
0.586 0.413 0.000
H04.2 Epiphora
0.586 0.414 0.000
H00.0 Hordeolum and other deep inflammation of eyelid
0.586 0.414 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.585 0.415 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.584 0.416 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.582 0.418 0.000
E56 Other vitamin deficiencies
0.582 0.418 0.000
E51 Thiamine deficiency
0.582 0.418 0.000
E50 Vitamin A deficiency
0.582 0.418 0.000
E60 Dietary zinc deficiency
0.582 0.418 0.000
E59 Dietary selenium deficiency
0.582 0.418 0.000
E54 Ascorbic acid deficiency
0.582 0.418 0.000
E52 Niacin deficiency [pellagra]
0.582 0.418 0.000
H20 Iridocyclitis
0.581 0.419 0.000
L24 Irritant contact dermatitis
0.579 0.420 0.001
L26 Exfoliative dermatitis
0.579 0.420 0.001
L22 Diaper [napkin] dermatitis
0.579 0.420 0.001
L71.9 Rosacea, unspecified
0.579 0.421 0.000
G63.2 Diabetic polyneuropathy
0.578 0.422 0.000
L08 Other local infections of skin and subcutaneous tissue
0.577 0.422 0.000
F20 Schizophrenia
0.578 0.422 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.577 0.423 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.577 0.423 0.000
E16.4 Abnormal secretion of gastrin
0.577 0.423 0.000
E16.3 Increased secretion of glucagon
0.577 0.423 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.574 0.426 0.000
H01 Other inflammation of eyelid
0.573 0.427 0.000
L25 Unspecified contact dermatitis
0.571 0.427 0.001
L66 Cicatricial alopecia [scarring hair loss]
0.571 0.428 0.002
E03.0 Congenital hypothyroidism with diffuse goitre
0.003 0.431 0.566
H16 Keratitis
0.569 0.431 0.000
G36.0 Neuromyelitis optica [Devic]
0.568 0.432 0.000
E03.1 Congenital hypothyroidism without goitre
0.003 0.433 0.563
L30.1 Dyshidrosis [pompholyx]
0.566 0.434 0.000
E14.4 With neurological complications
0.566 0.434 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.017 0.438 0.545
E00 Congenital iodine-deficiency syndrome
0.017 0.438 0.545
H18.6 Keratoconus
0.561 0.439 0.000
E58 Dietary calcium deficiency
0.560 0.440 0.000
L27.2 Dermatitis due to ingested food
0.558 0.441 0.000
L04.3 Acute lymphadenitis of lower limb
0.557 0.443 0.000
L71.8 Other rosacea
0.552 0.447 0.001
E55.0 Rickets, active
0.550 0.450 0.000
L27.9 Dermatitis due to unspecified substance taken internally
0.549 0.450 0.001
L27.8 Dermatitis due to other substances taken internally
0.549 0.450 0.001
L68 Hypertrichosis
0.546 0.452 0.002
F20.9 Schizophrenia, unspecified
0.547 0.453 0.000
H31 Other disorders of choroid
0.546 0.454 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.546 0.454 0.000
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified
0.545 0.455 0.000
L40-L45 Papulosquamous disorders
0.085 0.459 0.456
F20.0 Paranoid schizophrenia
0.537 0.463 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.017 0.464 0.519
G36.9 Acute disseminated demyelination, unspecified
0.535 0.465 0.000
G36.8 Other specified acute disseminated demyelination
0.535 0.465 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.535 0.465 0.000
E53.9 Vitamin B deficiency, unspecified
0.534 0.466 0.000
F60-F69 Disorders of adult personality and behaviour
0.534 0.466 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.534 0.466 0.000
Q35-Q37 Cleft lip and cleft palate
0.533 0.467 0.000
L04.9 Acute lymphadenitis, unspecified
0.532 0.468 0.000
Q74 Other congenital malformations of limb(s)
0.532 0.468 0.000
L05.9 Pilonidal cyst without abscess
0.528 0.472 0.000
H15 Disorders of sclera
0.526 0.474 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.526 0.474 0.000
L10-L14 Bullous disorders
0.492 0.475 0.034
H03 Disorders of eyelid in diseases classified elsewhere
0.524 0.476 0.000
E05.5 Thyroid crisis or storm
0.004 0.476 0.520
E05.4 Thyrotoxicosis factitia
0.004 0.476 0.520
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.004 0.476 0.520
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.004 0.476 0.520
Q78 Other osteochondrodysplasias
0.523 0.477 0.000
L23.1 Allergic contact dermatitis due to adhesives
0.521 0.478 0.001
Q30-Q34 Congenital malformations of the respiratory system
0.522 0.478 0.000
Q65 Congenital deformities of hip
0.522 0.478 0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified
0.521 0.479 0.000
L70.0 Acne vulgaris
0.520 0.480 0.001
L01.0 Impetigo [any organism] [any site]
0.519 0.481 0.000
L71.0 Perioral dermatitis
0.518 0.481 0.001
H17.8 Other corneal scars and opacities
0.519 0.481 0.000
H04.8 Other disorders of lachrymal system
0.518 0.482 0.000
L21.8 Other seborrhoeic dermatitis
0.516 0.483 0.001
L21.1 Seborrhoeic infantile dermatitis
0.516 0.483 0.001
L21.0 Seborrhoea capitis
0.516 0.483 0.001
F23 Acute and transient psychotic disorders
0.515 0.485 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.514 0.486 0.000
E63.9 Nutritional deficiency, unspecified
0.514 0.486 0.000
H16.0 Corneal ulcer
0.513 0.487 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.510 0.489 0.000
L08.8 Other specified local infections of skin and subcutaneous tissue
0.510 0.490 0.000
L30.5 Pityriasis alba
0.506 0.493 0.000
L30.3 Infective dermatitis
0.506 0.493 0.000
L30.2 Cutaneous autosensitisation
0.506 0.493 0.000
L30.0 Nummular dermatitis
0.506 0.493 0.000
H01.0 Blepharitis
0.506 0.494 0.000
L23.9 Allergic contact dermatitis, unspecified cause
0.505 0.494 0.001
E06.5 Other chronic thyroiditis
0.009 0.494 0.497
E06.4 Drug-induced thyroiditis
0.009 0.494 0.497
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.009 0.494 0.497
E06.0 Acute thyroiditis
0.009 0.494 0.497
E05.8 Other thyrotoxicosis
0.004 0.496 0.500
Q66.3 Other congenital varus deformities of feet
0.503 0.497 0.000
F03 Unspecified dementia
0.502 0.498 0.000
Q66.0 Talipes equinovarus
0.502 0.498 0.000
Q22 Congenital malformations of pulmonary and tricuspid valves
0.502 0.498 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.501 0.498 0.000
Q21 Congenital malformations of cardiac septa
0.501 0.499 0.000
Q25 Congenital malformations of great arteries
0.497 0.503 0.000
E61.1 Iron deficiency
0.496 0.504 0.000
L70.9 Acne, unspecified
0.494 0.505 0.001
H21 Other disorders of iris and ciliary body
0.495 0.505 0.000
L50-L54 Urticaria and erythema
0.472 0.506 0.022
H20.9 Iridocyclitis, unspecified
0.493 0.507 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.492 0.508 0.000
L65.9 Nonscarring hair loss, unspecified
0.489 0.510 0.001
H19.1 Herpesviral keratitis and keratoconjunctivitis
0.490 0.510 0.000
H18.9 Disorder of cornea, unspecified
0.489 0.510 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.328 0.513 0.160
L30.4 Erythema intertrigo
0.487 0.513 0.000
Q23 Congenital malformations of aortic and mitral valves
0.486 0.514 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.483 0.517 0.000
F60 Specific personality disorders
0.483 0.517 0.000
Q66.2 Metatarsus varus
0.483 0.517 0.000
Q24 Other congenital malformations of heart
0.483 0.517 0.000
E13 Other specified diabetes mellitus
0.482 0.518 0.000
Q28 Other congenital malformations of circulatory system
0.481 0.519 0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest
0.481 0.519 0.000
Q66.6 Other congenital valgus deformities of feet
0.480 0.520 0.000
L43 Lichen planus
0.026 0.520 0.453
H32 Chorioretinal disorders in diseases classified elsewhere
0.478 0.522 0.000
G70-G73 Diseases of myoneural junction and muscle
0.478 0.522 0.000
E12.9 Without complications
0.476 0.524 0.000
E12.8 With unspecified complications
0.476 0.524 0.000
E12.7 With multiple complications
0.476 0.524 0.000
E12.6 With other specified complications
0.476 0.524 0.000
E12.5 With peripheral circulatory complications
0.476 0.524 0.000
E12.4 With neurological complications
0.476 0.524 0.000
E12.3 With ophthalmic complications
0.476 0.524 0.000
E12.2 With renal complications
0.476 0.524 0.000
E12.1 With ketoacidosis
0.476 0.524 0.000
E12.0 With coma
0.476 0.524 0.000
L01.1 Impetiginisation of other dermatoses
0.474 0.525 0.000
Q27 Other congenital malformations of peripheral vascular system
0.474 0.526 0.000
L40 Psoriasis
0.007 0.527 0.466
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine
0.473 0.527 0.000
Q75 Other congenital malformations of skull and face bones
0.473 0.527 0.000
Q73 Reduction defects of unspecified limb
0.473 0.527 0.000
Q72 Reduction defects of lower limb
0.473 0.527 0.000
Q71 Reduction defects of upper limb
0.473 0.527 0.000
Q70 Syndactyly
0.473 0.527 0.000
Q69 Polydactyly
0.473 0.527 0.000
Q68 Other congenital musculoskeletal deformities
0.473 0.527 0.000
L63.9 Alopecia areata, unspecified
0.472 0.527 0.001
L70.8 Other acne
0.470 0.529 0.001
L70.5 Acne excoriee des jeunes filles
0.470 0.529 0.001
L70.4 Infantile acne
0.470 0.529 0.001
L70.3 Acne tropica
0.470 0.529 0.001
L70.2 Acne varioliformis
0.470 0.529 0.001
L70.1 Acne conglobata
0.470 0.529 0.001
H04.0 Dacryoadenitis
0.470 0.530 0.000
Q66.7 Pes cavus
0.465 0.535 0.000
L23.8 Allergic contact dermatitis due to other agents
0.462 0.537 0.001
L23.7 Allergic contact dermatitis due to plants, except food
0.462 0.537 0.001
L23.6 Allergic contact dermatitis due to food in contact with the skin
0.462 0.537 0.001
L23.4 Allergic contact dermatitis due to dyes
0.462 0.537 0.001
L23.3 Allergic contact dermatitis due to drugs in contact with the skin
0.462 0.537 0.001
L23.2 Allergic contact dermatitis due to cosmetics
0.462 0.537 0.001
L23.0 Allergic contact dermatitis due to metals
0.462 0.537 0.001
H17.1 Other central corneal opacity
0.461 0.539 0.000
H17.0 Adherent leukoma
0.461 0.539 0.000
L40.9 Psoriasis, unspecified
0.000 0.540 0.460
E06.9 Thyroiditis, unspecified
0.008 0.541 0.450
E61.2 Magnesium deficiency
0.458 0.542 0.000
E63.8 Other specified nutritional deficiencies
0.457 0.542 0.000
E63.1 Imbalance of constituents of food intake
0.457 0.542 0.000
E63.0 Essential fatty acid [EFA] deficiency
0.457 0.542 0.000
Q66.9 Congenital deformity of feet, unspecified
0.457 0.542 0.000
Q66.5 Congenital pes planus
0.457 0.542 0.000
Q66.4 Talipes calcaneovalgus
0.457 0.542 0.000
Q66.1 Talipes calcaneovarus
0.457 0.542 0.000
F00 Dementia in Alzheimer's disease
0.457 0.543 0.000
H31.0 Chorioretinal scars
0.453 0.547 0.000
H04.9 Disorder of lachrymal system, unspecified
0.453 0.547 0.000
Q74.0 Other congenital malformations of upper limb(s), including shoulder girdle
0.453 0.547 0.000
E61.9 Deficiency of nutrient element, unspecified
0.452 0.548 0.000
E61.8 Deficiency of other specified nutrient elements
0.452 0.548 0.000
E61.7 Deficiency of multiple nutrient elements
0.452 0.548 0.000
E61.6 Vanadium deficiency
0.452 0.548 0.000
E61.5 Molybdenum deficiency
0.452 0.548 0.000
E61.4 Chromium deficiency
0.452 0.548 0.000
E61.3 Manganese deficiency
0.452 0.548 0.000
E61.0 Copper deficiency
0.452 0.548 0.000
H04.6 Other changes in lachrymal passages
0.452 0.548 0.000
L65.8 Other specified nonscarring hair loss
0.450 0.549 0.001
L65.2 Alopecia mucinosa
0.450 0.549 0.001
L65.1 Anagen effluvium
0.450 0.549 0.001
L65.0 Telogen effluvium
0.450 0.549 0.001
F20.8 Other schizophrenia
0.450 0.550 0.000
L43.9 Lichen planus, unspecified
0.001 0.550 0.449
Q26 Congenital malformations of great veins
0.450 0.550 0.000
Q20 Congenital malformations of cardiac chambers and connexions
0.450 0.550 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.450 0.550 0.000
L57.0 Actinic keratosis
0.000 0.551 0.449
L20.8 Other atopic dermatitis
0.448 0.552 0.001
E53.1 Pyridoxine deficiency
0.448 0.552 0.000
E53.0 Riboflavin deficiency
0.448 0.552 0.000
H20.8 Other iridocyclitis
0.448 0.552 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.448 0.552 0.000
F70-F79 Mental retardation
0.448 0.552 0.000
F80-F89 Disorders of psychological development
0.447 0.553 0.000
Q79.6 Ehlers-Danlos syndrome
0.446 0.554 0.000
H31.8 Other specified disorders of choroid
0.445 0.555 0.000
L40.5 Arthropathic psoriasis
0.000 0.555 0.444
E16.1 Other hypoglycaemia
0.444 0.556 0.001
L63.8 Other alopecia areata
0.443 0.556 0.001
L63.2 Ophiasis
0.443 0.556 0.001
L63.1 Alopecia universalis
0.443 0.556 0.001
L63.0 Alopecia (capitis) totalis
0.443 0.556 0.001
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.443 0.557 0.000
H30 Chorioretinal inflammation
0.441 0.559 0.000
F23.9 Acute and transient psychotic disorder, unspecified
0.441 0.559 0.000
Q17 Other congenital malformations of ear
0.441 0.559 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.441 0.559 0.000
H18.1 Bullous keratopathy
0.438 0.562 0.000
E06.1 Subacute thyroiditis
0.010 0.563 0.427
E46 Unspecified protein-energy malnutrition
0.436 0.564 0.000
H01.1 Non-infectious dermatoses of eyelid
0.436 0.564 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.435 0.565 0.001
E45 Retarded development following protein-energy malnutrition
0.435 0.565 0.001
E43 Unspecified severe protein-energy malnutrition
0.435 0.565 0.001
E42 Marasmic kwashiorkor
0.435 0.565 0.001
E41 Nutritional marasmus
0.435 0.565 0.001
E40 Kwashiorkor
0.435 0.565 0.001
Q35 Cleft palate
0.434 0.566 0.000
H55-H59 Other disorders of eye and adnexa
0.431 0.569 0.000
H18.2 Other corneal oedema
0.431 0.569 0.000
F60.3 Emotionally unstable personality disorder
0.430 0.570 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.429 0.571 0.000
L20.0 Besnier's prurigo
0.428 0.571 0.001
H18.7 Other corneal deformities
0.428 0.571 0.000
H18.3 Changes in corneal membranes
0.428 0.571 0.000
H18.0 Corneal pigmentations and deposits
0.428 0.571 0.000
G30-G32 Other degenerative diseases of the nervous system
0.428 0.572 0.000
L20.9 Atopic dermatitis, unspecified
0.427 0.572 0.001
H53-H54 Visual disturbances and blindness
0.427 0.573 0.000
Q78.0 Osteogenesis imperfecta
0.426 0.574 0.000
H20.1 Chronic iridocyclitis
0.426 0.574 0.000
G64 Other disorders of peripheral nervous system
0.425 0.575 0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos
0.424 0.576 0.000
H16.8 Other keratitis
0.424 0.576 0.000
L62.8 Nail disorders in other diseases classified elsewhere
0.422 0.577 0.001
L62.0 Clubbed nail pachydermoperiostosis
0.422 0.577 0.001
L64.9 Androgenic alopecia, unspecified
0.422 0.577 0.001
L64.8 Other androgenic alopecia
0.422 0.577 0.001
L64.0 Drug-induced androgenic alopecia
0.422 0.577 0.001
L67.9 Hair colour and hair shaft abnormality, unspecified
0.422 0.577 0.001
L67.8 Other hair colour and hair shaft abnormalities
0.422 0.577 0.001
L67.1 Variations in hair colour
0.422 0.577 0.001
L67.0 Trichorrhexis nodosa
0.422 0.577 0.001
L74.9 Eccrine sweat disorder, unspecified
0.422 0.577 0.001
L74.8 Other eccrine sweat disorders
0.422 0.577 0.001
L74.4 Anhidrosis
0.422 0.577 0.001
L74.3 Miliaria, unspecified
0.422 0.577 0.001
L74.2 Miliaria profunda
0.422 0.577 0.001
L74.1 Miliaria crystallina
0.422 0.577 0.001
L74.0 Miliaria rubra
0.422 0.577 0.001
L75.9 Apocrine sweat disorder, unspecified
0.422 0.577 0.001
L75.8 Other apocrine sweat disorders
0.422 0.577 0.001
L75.2 Apocrine miliaria
0.422 0.577 0.001
L75.1 Chromhidrosis
0.422 0.577 0.001
L75.0 Bromhidrosis
0.422 0.577 0.001
Q65.8 Other congenital deformities of hip
0.423 0.577 0.000
H03.8 Involvement of eyelid in other diseases classified elsewhere
0.422 0.578 0.000
H21.1 Other vascular disorders of iris and ciliary body
0.421 0.579 0.000
L23.5 Allergic contact dermatitis due to other chemical products
0.419 0.580 0.001
H15.0 Scleritis
0.419 0.581 0.000
F28 Other nonorganic psychotic disorders
0.419 0.581 0.000
F24 Induced delusional disorder
0.419 0.581 0.000
F21 Schizotypal disorder
0.419 0.581 0.000
G63.8 Polyneuropathy in other diseases classified elsewhere
0.419 0.581 0.000
G63.6 Polyneuropathy in other musculoskeletal disorders
0.419 0.581 0.000
G63.5 Polyneuropathy in systemic connective tissue disorders
0.419 0.581 0.000
G63.4 Polyneuropathy in nutritional deficiency
0.419 0.581 0.000
G63.3 Polyneuropathy in other endocrine and metabolic diseases
0.419 0.581 0.000
G63.1 Polyneuropathy in neoplastic disease
0.419 0.581 0.000
G63.0 Polyneuropathy in infectious and parasitic diseases classified elsewhere
0.419 0.581 0.000
E50.9 Vitamin A deficiency, unspecified
0.417 0.582 0.000
E50.8 Other manifestations of vitamin A deficiency
0.417 0.582 0.000
E50.7 Other ocular manifestations of vitamin A deficiency
0.417 0.582 0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.417 0.582 0.000
E50.5 Vitamin A deficiency with night blindness
0.417 0.582 0.000
E50.4 Vitamin A deficiency with keratomalacia
0.417 0.582 0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.417 0.582 0.000
E50.2 Vitamin A deficiency with corneal xerosis
0.417 0.582 0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.417 0.582 0.000
E50.0 Vitamin A deficiency with conjunctival xerosis
0.417 0.582 0.000
E51.9 Thiamine deficiency, unspecified
0.417 0.582 0.000
E51.8 Other manifestations of thiamine deficiency
0.417 0.582 0.000
E51.2 Wernicke's encephalopathy
0.417 0.582 0.000
E51.1 Beriberi
0.417 0.582 0.000
E56.9 Vitamin deficiency, unspecified
0.417 0.582 0.000
E56.8 Deficiency of other vitamins
0.417 0.582 0.000
E56.1 Deficiency of vitamin K
0.417 0.582 0.000
E56.0 Deficiency of vitamin E
0.417 0.582 0.000
E64.9 Sequelae of unspecified nutritional deficiency
0.417 0.582 0.000
E64.8 Sequelae of other nutritional deficiencies
0.417 0.582 0.000
E64.3 Sequelae of rickets
0.417 0.582 0.000
E64.2 Sequelae of vitamin C deficiency
0.417 0.582 0.000
E64.1 Sequelae of vitamin A deficiency
0.417 0.582 0.000
E64.0 Sequelae of protein-energy malnutrition
0.417 0.582 0.000
F23.0 Acute polymorphic psychotic disorder without symptoms of schizophrenia
0.417 0.583 0.000
H20.2 Lens-induced iridocyclitis
0.417 0.583 0.000
L24.9 Irritant contact dermatitis, unspecified cause
0.415 0.584 0.001
L24.8 Irritant contact dermatitis due to other agents
0.415 0.584 0.001
L24.7 Irritant contact dermatitis due to plants, except food
0.415 0.584 0.001
L24.6 Irritant contact dermatitis due to food in contact with the skin
0.415 0.584 0.001
L24.5 Irritant contact dermatitis due to other chemical products
0.415 0.584 0.001
L24.4 Irritant contact dermatitis due to drugs in contact with the skin
0.415 0.584 0.001
L24.3 Irritant contact dermatitis due to cosmetics
0.415 0.584 0.001
L24.2 Irritant contact dermatitis due to solvents
0.415 0.584 0.001
L24.1 Irritant contact dermatitis due to oils and greases
0.415 0.584 0.001
L24.0 Irritant contact dermatitis due to detergents
0.415 0.584 0.001
Chapter XXII Codes for special purposes
0.415 0.584 0.000
Q21.0 Ventricular septal defect
0.416 0.584 0.000
Q31 Congenital malformations of larynx
0.415 0.585 0.000
F00.9 Dementia in Alzheimer's disease, unspecified
0.415 0.585 0.000
Q22.5 Ebstein's anomaly
0.415 0.585 0.000
L08.1 Erythrasma
0.414 0.586 0.000
F20.6 Simple schizophrenia
0.414 0.586 0.000
F20.4 Postschizophrenic depression
0.414 0.586 0.000
F20.3 Undifferentiated schizophrenia
0.414 0.586 0.000
F20.2 Catatonic schizophrenia
0.414 0.586 0.000
F20.1 Hebephrenic schizophrenia
0.414 0.586 0.000
Q96 Turner's syndrome
0.414 0.586 0.000
F20.5 Residual schizophrenia
0.414 0.586 0.000
G70 Myasthenia gravis and other myoneural disorders
0.414 0.586 0.000
F01 Vascular dementia
0.412 0.587 0.000
H19.8 Other disorders of sclera and cornea in diseases classified elsewhere
0.411 0.589 0.000
H19.2 Keratitis and keratoconjunctivitis in other infectious and parasitic diseases classified elsewhere
0.411 0.589 0.000
H19.0 Scleritis and episcleritis in diseases classified elsewhere
0.411 0.589 0.000
H16.4 Corneal neovascularisation
0.411 0.589 0.000
L25.8 Unspecified contact dermatitis due to other agents
0.410 0.589 0.001
L25.5 Unspecified contact dermatitis due to plants, except food
0.410 0.589 0.001
L25.4 Unspecified contact dermatitis due to food in contact with the skin
0.410 0.589 0.001
L25.3 Unspecified contact dermatitis due to other chemical products
0.410 0.589 0.001
L25.2 Unspecified contact dermatitis due to dyes
0.410 0.589 0.001
L25.1 Unspecified contact dermatitis due to drugs in contact with the skin
0.410 0.589 0.001
L25.0 Unspecified contact dermatitis due to cosmetics
0.410 0.589 0.001
L66.8 Other cicatricial alopecia
0.409 0.590 0.001
L66.4 Folliculitis ulerythematosa reticulata
0.409 0.590 0.001
L66.3 Perifolliculitis capitis abscedens
0.409 0.590 0.001
L66.2 Folliculitis decalvans
0.409 0.590 0.001
L66.1 Lichen planopilaris
0.409 0.590 0.001
L66.0 Pseudopelade
0.409 0.590 0.001
Q25.0 Patent ductus arteriosus
0.409 0.591 0.000
Q21.8 Other congenital malformations of cardiac septa
0.409 0.591 0.000
H16.3 Interstitial and deep keratitis
0.408 0.592 0.000
H19.3 Keratitis and keratoconjunctivitis in other diseases classified elsewhere
0.408 0.592 0.000
H18.4 Corneal degeneration
0.408 0.592 0.000
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit
0.404 0.596 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.012 0.597 0.391
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.012 0.597 0.391
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.012 0.597 0.391
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.012 0.597 0.391
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.012 0.597 0.391
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.012 0.597 0.391
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.012 0.597 0.391
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.012 0.597 0.391
L25.9 Unspecified contact dermatitis, unspecified cause
0.402 0.597 0.001
H01.8 Other specified inflammation of eyelid
0.401 0.599 0.000
F50 Eating disorders
0.401 0.599 0.000
L42 Pityriasis rosea
0.051 0.599 0.350
L30.9 Dermatitis, unspecified
0.399 0.601 0.000
H16.1 Other superficial keratitis without conjunctivitis
0.398 0.602 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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