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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs9276423
log Bayes Factor = 168.231
Chromosome 6   position 32,710,855  (GRCh37) Explore rs9276423 on Ensembl!
Variant rs9276423 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
E16.2 Hypoglycaemia, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.000 1.000
E16 Other disorders of pancreatic internal secretion
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
D86 Sarcoidosis
0.000 0.001 0.999
H36.0 Diabetic retinopathy
0.000 0.001 0.999
D80-D89 Certain disorders involving the immune mechanism
0.000 0.001 0.999
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.001 0.999
E00-E07 Disorders of thyroid gland
0.000 0.001 0.999
D86.9 Sarcoidosis, unspecified
0.000 0.001 0.999
H36 Retinal disorders in diseases classified elsewhere
0.000 0.002 0.998
D50-D53 Nutritional anaemias
0.000 0.002 0.998
H30-H36 Disorders of choroid and retina
0.000 0.002 0.998
L40.9 Psoriasis, unspecified
0.997 0.003 0.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.004 0.996
Chapter VII Diseases of the eye and adnexa
0.000 0.005 0.995
D50.9 Iron deficiency anaemia, unspecified
0.000 0.005 0.995
D50 Iron deficiency anaemia
0.000 0.005 0.995
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.006 0.994
L40 Psoriasis
0.992 0.008 0.000
# Top node
0.000 0.008 0.992
E14.9 Without complications
0.000 0.010 0.990
E10.2 With renal complications
0.000 0.010 0.990
H33 Retinal detachments and breaks
0.000 0.012 0.988
E10.4 With neurological complications
0.000 0.012 0.988
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.013 0.987
L40.5 Arthropathic psoriasis
0.986 0.014 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.000 0.017 0.983
E14.3 With ophthalmic complications
0.000 0.017 0.983
G37 Other demyelinating diseases of central nervous system
0.000 0.017 0.983
L60-L75 Disorders of skin appendages
0.000 0.022 0.978
E50-E64 Other nutritional deficiencies
0.000 0.022 0.978
M06 Other rheumatoid arthritis
0.977 0.023 0.000
M06.9 Rheumatoid arthritis, unspecified
0.977 0.023 0.000
E10.5 With peripheral circulatory complications
0.000 0.026 0.974
H33.3 Retinal breaks without detachment
0.000 0.028 0.972
L71 Rosacea
0.000 0.033 0.967
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.957 0.043 0.000
L71.9 Rosacea, unspecified
0.000 0.045 0.955
M05-M14 Inflammatory polyarthropathies
0.949 0.051 0.000
M06.3 Rheumatoid nodule
0.947 0.053 0.000
M05 Seropositive rheumatoid arthritis
0.947 0.053 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.000 0.054 0.946
M05.9 Seropositive rheumatoid arthritis, unspecified
0.945 0.055 0.000
E55 Vitamin D deficiency
0.000 0.057 0.943
D86.0 Sarcoidosis of lung
0.000 0.060 0.940
G37.9 Demyelinating disease of central nervous system, unspecified
0.000 0.063 0.937
H04 Disorders of lachrymal system
0.000 0.067 0.933
L10-L14 Bullous disorders
0.000 0.072 0.928
L72 Follicular cysts of skin and subcutaneous tissue
0.000 0.075 0.925
D51 Vitamin B12 deficiency anaemia
0.000 0.079 0.921
H06.2 Dysthyroid exophthalmos
0.000 0.080 0.920
E55.9 Vitamin D deficiency, unspecified
0.000 0.082 0.918
R31 Unspecified haematuria
0.918 0.082 0.000
L72.1 Trichilemmal cyst
0.000 0.087 0.913
L13 Other bullous disorders
0.000 0.093 0.907
M06.0 Seronegative rheumatoid arthritis
0.903 0.097 0.000
H33.2 Serous retinal detachment
0.000 0.098 0.902
L50-L54 Urticaria and erythema
0.000 0.102 0.898
H33.4 Traction detachment of retina
0.000 0.102 0.898
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.897 0.103 0.000
Chapter VI Diseases of the nervous system
0.000 0.103 0.897
H04.8 Other disorders of lachrymal system
0.000 0.104 0.896
L20-L30 Dermatitis and eczema
0.000 0.105 0.895
L13.0 Dermatitis herpetiformis
0.000 0.107 0.893
H04.1 Other disorders of lachrymal gland
0.000 0.111 0.889
M07 Psoriatic and enteropathic arthropathies
0.888 0.112 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.887 0.113 0.000
E53 Deficiency of other B group vitamins
0.000 0.121 0.879
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.878 0.122 0.000
H05 Disorders of orbit
0.000 0.127 0.873
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.868 0.132 0.000
G37.8 Other specified demyelinating diseases of central nervous system
0.000 0.134 0.866
D86.8 Sarcoidosis of other and combined sites
0.000 0.141 0.859
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.000 0.142 0.858
H31 Other disorders of choroid
0.000 0.143 0.856
L70 Acne
0.000 0.145 0.855
H46-H48 Disorders of optic nerve and visual pathways
0.000 0.149 0.851
E14.6 With other specified complications
0.000 0.150 0.850
M07.3 Other psoriatic arthropathies
0.848 0.152 0.000
K90 Intestinal malabsorption
0.000 0.155 0.845
H04.3 Acute and unspecified inflammation of lachrymal passages
0.000 0.156 0.844
L40-L45 Papulosquamous disorders
0.771 0.159 0.070
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.840 0.160 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.000 0.163 0.837
E14.8 With unspecified complications
0.000 0.163 0.837
M06.34 Rheumatoid nodule (Hand)
0.833 0.167 0.000
L27 Dermatitis due to substances taken internally
0.000 0.167 0.833
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.000 0.167 0.833
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.175 0.825
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.176 0.824
E40-E46 Malnutrition
0.000 0.177 0.823
E10.0 With coma
0.000 0.185 0.815
M06.98 Rheumatoid arthritis, unspecified (Other)
0.809 0.191 0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.000 0.191 0.809
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.000 0.197 0.803
L72.8 Other follicular cysts of skin and subcutaneous tissue
0.000 0.198 0.802
M07.39 Other psoriatic arthropathies (Site unspecified)
0.802 0.198 0.000
E10.7 With multiple complications
0.000 0.198 0.802
L21 Seborrhoeic dermatitis
0.000 0.202 0.798
M06.32 Rheumatoid nodule (Upper arm)
0.796 0.204 0.000
E10.8 With unspecified complications
0.000 0.205 0.795
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.794 0.206 0.000
K90.9 Intestinal malabsorption, unspecified
0.000 0.210 0.790
L53 Other erythematous conditions
0.000 0.211 0.789
H05.2 Exophthalmic conditions
0.000 0.213 0.787
D69 Purpura and other haemorrhagic conditions
0.000 0.215 0.785
H00 Hordeolum and chalazion
0.000 0.216 0.784
L65 Other nonscarring hair loss
0.000 0.216 0.784
M06.37 Rheumatoid nodule (Ankle and foot)
0.781 0.219 0.000
E14.2 Withrenal complications
0.000 0.219 0.780
H31.0 Chorioretinal scars
0.000 0.220 0.780
L71.8 Other rosacea
0.000 0.223 0.777
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.775 0.225 0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.770 0.230 0.000
L51 Erythema multiforme
0.000 0.231 0.769
E53.8 Deficiency of other specified B group vitamins
0.000 0.233 0.767
M06.33 Rheumatoid nodule (Forearm)
0.763 0.237 0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.762 0.238 0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.761 0.239 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.000 0.241 0.759
D86.1 Sarcoidosis of lymph nodes
0.000 0.242 0.758
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.757 0.243 0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.752 0.247 0.000
L40.0 Psoriasis vulgaris
0.752 0.248 0.000
M06.4 Inflammatory polyarthropathy
0.750 0.250 0.000
D50.1 Sideropenic dysphagia
0.000 0.254 0.746
L40.8 Other psoriasis
0.746 0.254 0.000
L40.1 Generalised pustular psoriasis
0.744 0.256 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.000 0.257 0.743
E10.6 With other specified complications
0.000 0.257 0.743
H00.0 Hordeolum and other deep inflammation of eyelid
0.000 0.260 0.740
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.740 0.260 0.000
L52 Erythema nodosum
0.000 0.261 0.739
L70.0 Acne vulgaris
0.000 0.262 0.738
M05.1 Rheumatoid lung disease
0.738 0.262 0.000
D89.9 Disorder involving the immune mechanism, unspecified
0.000 0.263 0.737
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.735 0.265 0.000
E54 Ascorbic acid deficiency
0.000 0.265 0.735
E14.5 With peripheral circulatory complications
0.000 0.266 0.734
L27.1 Localised skin eruption due to drugs and medicaments
0.000 0.266 0.734
Chapter XXII Codes for special purposes
0.000 0.267 0.733
H25-H28 Disorders of lens
0.000 0.268 0.732
L21.9 Seborrhoeic dermatitis, unspecified
0.000 0.271 0.729
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.729 0.271 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.274 0.726
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.724 0.276 0.000
G36 Other acute disseminated demyelination
0.000 0.277 0.723
H03 Disorders of eyelid in diseases classified elsewhere
0.000 0.277 0.723
L27.0 Generalised skin eruption due to drugs and medicaments
0.000 0.277 0.723
E53.9 Vitamin B deficiency, unspecified
0.000 0.278 0.722
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.717
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.283 0.717
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.283 0.717
E16.4 Abnormal secretion of gastrin
0.000 0.283 0.717
E16.3 Increased secretion of glucagon
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
D81 Combined immunodeficiencies
0.000 0.283 0.716
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.284 0.716
E00 Congenital iodine-deficiency syndrome
0.000 0.284 0.716
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.284 0.716
M06.30 Rheumatoid nodule (Multiple sites)
0.716 0.284 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.285 0.715
D84 Other immunodeficiencies
0.000 0.286 0.714
L40.2 Acrodermatitis continua
0.711 0.288 0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.709 0.291 0.000
M06.36 Rheumatoid nodule (Lower leg)
0.708 0.292 0.000
L42 Pityriasis rosea
0.678 0.292 0.030
M05.8 Other seropositive rheumatoid arthritis
0.706 0.294 0.000
L40.4 Guttate psoriasis
0.706 0.294 0.000
H46 Optic neuritis
0.000 0.294 0.706
G37.5 Concentric sclerosis [Balo]
0.000 0.295 0.704
G37.4 Subacute necrotising myelitis
0.000 0.295 0.704
G37.2 Central pontine myelinolysis
0.000 0.295 0.704
G37.1 Central demyelination of corpus callosum
0.000 0.295 0.704
G37.0 Diffuse sclerosis
0.000 0.295 0.704
L71.1 Rhinophyma
0.000 0.296 0.704
H05.0 Acute inflammation of orbit
0.000 0.297 0.703
H55-H59 Other disorders of eye and adnexa
0.000 0.297 0.703
D52 Folate deficiency anaemia
0.000 0.298 0.702
L75 Apocrine sweat disorders
0.000 0.298 0.701
L74 Eccrine sweat disorders
0.000 0.298 0.701
L67 Hair colour and hair shaft abnormalities
0.000 0.298 0.701
L64 Androgenic alopecia
0.000 0.298 0.701
L62 Nail disorders in diseases classified elsewhere
0.000 0.298 0.701
H26 Other cataract
0.000 0.299 0.701
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.299 0.701
E63 Other nutritional deficiencies
0.000 0.299 0.701
E50 Vitamin A deficiency
0.000 0.299 0.701
E60 Dietary zinc deficiency
0.000 0.299 0.701
E59 Dietary selenium deficiency
0.000 0.299 0.701
E52 Niacin deficiency [pellagra]
0.000 0.299 0.701
M06.2 Rheumatoid bursitis
0.700 0.299 0.000
L53.8 Other specified erythematous conditions
0.000 0.300 0.700
D82 Immunodeficiency associated with other major defects
0.000 0.302 0.698
E46 Unspecified protein-energy malnutrition
0.000 0.303 0.697
H26.4 After-cataract
0.000 0.304 0.696
H53-H54 Visual disturbances and blindness
0.000 0.305 0.695
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.694 0.306 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.306 0.694
L71.0 Perioral dermatitis
0.000 0.307 0.693
L63 Alopecia areata
0.000 0.308 0.691
L51.9 Erythema multiforme, unspecified
0.000 0.309 0.691
D53 Other nutritional anaemias
0.000 0.309 0.691
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.310 0.690
E14.0 With coma
0.000 0.311 0.689
E51 Thiamine deficiency
0.000 0.312 0.688
M06.1 Adult-onset Still's disease
0.687 0.313 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.680 0.320 0.000
D86.3 Sarcoidosis of skin
0.000 0.320 0.680
H47 Other disorders of optic [2nd] nerve and visual pathways
0.000 0.320 0.680
M06.39 Rheumatoid nodule (Site unspecified)
0.679 0.321 0.000
M06.38 Rheumatoid nodule (Other)
0.679 0.321 0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.679 0.321 0.000
M06.31 Rheumatoid nodule (Shoulder region)
0.679 0.321 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.679 0.321 0.000
M05.0 Felty's syndrome
0.679 0.321 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.321 0.679
M08 Juvenile arthritis
0.678 0.321 0.000
H06.3 Other disorders of orbit in diseases classified elsewhere
0.000 0.321 0.678
H06.1 Parasitic infestation of orbit in diseases classified elsewhere
0.000 0.321 0.678
H06.0 Disorders of lachrymal system in diseases classified elsewhere
0.000 0.321 0.678
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.678 0.322 0.000
E55.0 Rickets, active
0.000 0.324 0.676
L25 Unspecified contact dermatitis
0.000 0.324 0.675
M06.8 Other specified rheumatoid arthritis
0.674 0.326 0.000
M05.2 Rheumatoid vasculitis
0.674 0.326 0.000
D83 Common variable immunodeficiency
0.000 0.326 0.674
E61 Deficiency of other nutrient elements
0.000 0.326 0.673
E14.1 With ketoacidosis
0.000 0.328 0.672
L70.9 Acne, unspecified
0.000 0.329 0.671
E56 Other vitamin deficiencies
0.000 0.332 0.668
L40.3 Pustulosis palmaris et plantaris
0.668 0.332 0.000
M14 Arthropathies in other diseases classified elsewhere
0.666 0.333 0.000
L14 Bullous disorders in diseases classified elsewhere
0.000 0.334 0.666
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.000 0.337 0.663
L72.2 Steatocystoma multiplex
0.000 0.337 0.663
L66 Cicatricial alopecia [scarring hair loss]
0.000 0.337 0.663
D51.8 Other vitamin B12 deficiency anaemias
0.000 0.340 0.660
D51.2 Transcobalamin II deficiency
0.000 0.340 0.660
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.000 0.340 0.660
L53.0 Toxic erythema
0.000 0.340 0.660
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.000 0.341 0.659
H33.1 Retinoschisis and retinal cysts
0.000 0.341 0.659
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.000 0.341 0.659
M07.31 Other psoriatic arthropathies (Shoulder region)
0.659 0.341 0.000
E58 Dietary calcium deficiency
0.000 0.343 0.657
L10 Pemphigus
0.000 0.345 0.655
L68 Hypertrichosis
0.000 0.347 0.652
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.349 0.651
L13.9 Bullous disorder, unspecified
0.000 0.349 0.650
L13.8 Other specified bullous disorders
0.000 0.349 0.650
L13.1 Subcorneal pustular dermatitis
0.000 0.349 0.650
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.650 0.350 0.000
D55-D59 Haemolytic anaemias
0.000 0.351 0.649
M06.08 Seronegative rheumatoid arthritis (Other)
0.648 0.352 0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.648 0.352 0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.648 0.352 0.000
H04.0 Dacryoadenitis
0.000 0.353 0.647
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.645 0.355 0.000
L54 Erythema in diseases classified elsewhere
0.000 0.356 0.644
L65.9 Nonscarring hair loss, unspecified
0.000 0.356 0.644
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.642 0.358 0.000
L24 Irritant contact dermatitis
0.000 0.358 0.641
L26 Exfoliative dermatitis
0.000 0.358 0.641
L22 Diaper [napkin] dermatitis
0.000 0.358 0.641
H26.2 Complicated cataract
0.000 0.359 0.641
D89.0 Polyclonal hypergammaglobulinaemia
0.000 0.362 0.637
M07.5 Arthropathy in ulcerative colitis
0.637 0.363 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.637 0.363 0.000
M07.2 Psoriatic spondylitis
0.637 0.363 0.000
M07.1 Arthritis mutilans
0.637 0.363 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.637 0.363 0.000
L23 Allergic contact dermatitis
0.000 0.363 0.637
M11 Other crystal arthropathies
0.636 0.363 0.000
H05.8 Other disorders of orbit
0.000 0.364 0.636
M07.30 Other psoriatic arthropathies (Multiple sites)
0.636 0.364 0.000
M07.38 Other psoriatic arthropathies (Other)
0.634 0.366 0.000
D67 Hereditary factor IX deficiency
0.000 0.367 0.633
D69.5 Secondary thrombocytopenia
0.000 0.369 0.631
E53.1 Pyridoxine deficiency
0.000 0.370 0.630
E53.0 Riboflavin deficiency
0.000 0.370 0.630
H04.6 Other changes in lachrymal passages
0.000 0.371 0.629
E13 Other specified diabetes mellitus
0.000 0.373 0.627
M07.34 Other psoriatic arthropathies (Hand)
0.626 0.374 0.000
H05.5 Retained (old) foreign body following penetrating wound of orbit
0.000 0.374 0.626
H05.3 Deformity of orbit
0.000 0.374 0.626
M06.04 Seronegative rheumatoid arthritis (Hand)
0.621 0.379 0.000
H54 Blindness and low vision
0.000 0.380 0.620
U88 Agent resistant to multiple antibiotics
0.000 0.380 0.620
L44 Other papulosquamous disorders
0.572 0.380 0.048
H31.9 Disorder of choroid, unspecified
0.000 0.381 0.619
M07.6 Other enteropathic arthropathies
0.618 0.382 0.000
H05.9 Disorder of orbit, unspecified
0.000 0.382 0.617
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.617 0.383 0.000
H31.4 Choroidal detachment
0.000 0.386 0.614
H31.2 Hereditary choroidal dystrophy
0.000 0.386 0.614
L70.8 Other acne
0.000 0.387 0.613
L70.5 Acne excoriee des jeunes filles
0.000 0.387 0.613
L70.4 Infantile acne
0.000 0.387 0.613
L70.3 Acne tropica
0.000 0.387 0.613
L70.2 Acne varioliformis
0.000 0.387 0.613
L70.1 Acne conglobata
0.000 0.387 0.613
D89.2 Hypergammaglobulinaemia, unspecified
0.000 0.387 0.613
H55 Nystagmus and other irregular eye movements
0.000 0.387 0.613
H05.4 Enophthalmos
0.000 0.389 0.611
H58 Other disorders of eye and adnexa in diseases classified elsewhere
0.000 0.389 0.611
L27.2 Dermatitis due to ingested food
0.000 0.389 0.611
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere
0.000 0.390 0.610
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.608 0.391 0.000
M07.33 Other psoriatic arthropathies (Forearm)
0.608 0.392 0.000
M07.32 Other psoriatic arthropathies (Upper arm)
0.608 0.392 0.000
H18 Other disorders of cornea
0.000 0.392 0.608
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.606 0.393 0.000
K90.3 Pancreatic steatorrhoea
0.000 0.394 0.606
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.394 0.606
K90.1 Tropical sprue
0.000 0.394 0.606
D69.4 Other primary thrombocytopenia
0.000 0.395 0.605
E07 Other disorders of thyroid
0.000 0.395 0.605
H16 Keratitis
0.000 0.395 0.605
L45 Papulosquamous disorders in diseases classified elsewhere
0.553 0.397 0.050
D69.2 Other nonthrombocytopenic purpura
0.000 0.397 0.603
H31.8 Other specified disorders of choroid
0.000 0.397 0.603
G30-G32 Other degenerative diseases of the nervous system
0.000 0.398 0.602
D80 Immunodeficiency with predominantly antibody defects
0.000 0.398 0.602
H31.3 Choroidal haemorrhage and rupture
0.000 0.399 0.601
D89.3 Immune reconstitution syndrome
0.000 0.399 0.600
L20 Atopic dermatitis
0.000 0.400 0.600
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.600 0.400 0.000
H01 Other inflammation of eyelid
0.000 0.401 0.599
L27.9 Dermatitis due to unspecified substance taken internally
0.000 0.402 0.597
L27.8 Dermatitis due to other substances taken internally
0.000 0.402 0.597
L11 Other acantholytic disorders
0.000 0.404 0.596
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.000 0.404 0.596
H30 Chorioretinal inflammation
0.000 0.406 0.594
H19.1 Herpesviral keratitis and keratoconjunctivitis
0.000 0.407 0.593
D69.8 Other specified haemorrhagic conditions
0.000 0.408 0.592
L41 Parapsoriasis
0.540 0.409 0.051
D51.3 Other dietary vitamin B12 deficiency anaemia
0.000 0.410 0.590
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.410 0.590
E45 Retarded development following protein-energy malnutrition
0.000 0.410 0.590
E43 Unspecified severe protein-energy malnutrition
0.000 0.410 0.590
E42 Marasmic kwashiorkor
0.000 0.410 0.590
E41 Nutritional marasmus
0.000 0.410 0.590
E40 Kwashiorkor
0.000 0.410 0.590
M05.19 Rheumatoid lung disease (Site unspecified)
0.588 0.412 0.000
H54.9 Unspecified visual impairment (binocular)
0.000 0.414 0.586
M07.36 Other psoriatic arthropathies (Lower leg)
0.585 0.415 0.000
L28 Lichen simplex chronicus and prurigo
0.000 0.416 0.584
E14.4 With neurological complications
0.000 0.416 0.584
E27.1 Primary adrenocortical insufficiency
0.000 0.418 0.582
H47.3 Other disorders of optic disk
0.000 0.418 0.582
M06.46 Inflammatory polyarthropathy (Lower leg)
0.580 0.420 0.000
H33.0 Retinal detachment with retinal break
0.000 0.423 0.577
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.576 0.423 0.000
E20-E35 Disorders of other endocrine glands
0.000 0.424 0.576
K90.8 Other intestinal malabsorption
0.000 0.424 0.576
E27 Other disorders of adrenal gland
0.000 0.426 0.574
H17 Corneal scars and opacities
0.000 0.427 0.573
L21.8 Other seborrhoeic dermatitis
0.000 0.428 0.572
L21.1 Seborrhoeic infantile dermatitis
0.000 0.428 0.572
L21.0 Seborrhoea capitis
0.000 0.428 0.572
L53.3 Other chronic figurate erythema
0.000 0.434 0.566
L53.2 Erythema marginatum
0.000 0.434 0.566
L53.1 Erythema annulare centrifugum
0.000 0.434 0.566
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified
0.000 0.434 0.566
E05.8 Other thyrotoxicosis
0.000 0.435 0.564
H18.6 Keratoconus
0.000 0.436 0.564
E04 Other non-toxic goitre
0.000 0.436 0.564
M14.6 Neuropathic arthropathy
0.563 0.437 0.000
L65.8 Other specified nonscarring hair loss
0.000 0.438 0.562
L65.2 Alopecia mucinosa
0.000 0.438 0.562
L65.1 Anagen effluvium
0.000 0.438 0.562
L65.0 Telogen effluvium
0.000 0.438 0.562
H31.1 Choroidal degeneration
0.000 0.440 0.559
D84.1 Defects in the complement system
0.000 0.442 0.558
H05.1 Chronic inflammatory disorders of orbit
0.000 0.443 0.557
L51.8 Other erythema multiforme
0.000 0.448 0.551
L51.2 Toxic epidermal necrolysis [Lyell]
0.000 0.448 0.551
L51.0 Nonbullous erythema multiforme
0.000 0.448 0.551
D59 Acquired haemolytic anaemia
0.000 0.453 0.547
H58.8 Visual disturbances in diseases classified elsewhere
0.000 0.455 0.545
H54.0 Blindness, both eyes
0.000 0.455 0.545
H19.3 Keratitis and keratoconjunctivitis in other diseases classified elsewhere
0.000 0.457 0.543
L30 Other dermatitis
0.000 0.459 0.541
H04.9 Disorder of lachrymal system, unspecified
0.000 0.459 0.541
D84.8 Other specified immunodeficiencies
0.000 0.460 0.540
D89.1 Cryoglobulinaemia
0.000 0.461 0.539
M06.48 Inflammatory polyarthropathy (Other)
0.538 0.462 0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.538 0.462 0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.538 0.462 0.000
M06.44 Inflammatory polyarthropathy (Hand)
0.538 0.462 0.000
M06.43 Inflammatory polyarthropathy (Forearm)
0.538 0.462 0.000
M06.42 Inflammatory polyarthropathy (Upper arm)
0.538 0.462 0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.538 0.462 0.000
L43 Lichen planus
0.515 0.462 0.023
H03.1 Involvement of eyelid in other infectious diseases classified elsewhere
0.000 0.463 0.536
P10-P15 Birth trauma
0.000 0.465 0.535
L12 Pemphigoid
0.000 0.467 0.533
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)
0.532 0.468 0.000
D82.1 Di George's syndrome
0.000 0.468 0.532
E61.2 Magnesium deficiency
0.000 0.470 0.530
D70-D77 Other diseases of blood and blood-forming organs
0.000 0.470 0.530
G36.0 Neuromyelitis optica [Devic]
0.000 0.471 0.529
M05.18 Rheumatoid lung disease (Other)
0.529 0.471 0.000
M05.17 Rheumatoid lung disease (Ankle and foot)
0.529 0.471 0.000
M05.16 Rheumatoid lung disease (Lower leg)
0.529 0.471 0.000
M05.15 Rheumatoid lung disease (Pelvic region and thigh)
0.529 0.471 0.000
M05.14 Rheumatoid lung disease (Hand)
0.529 0.471 0.000
M05.13 Rheumatoid lung disease (Forearm)
0.529 0.471 0.000
M05.12 Rheumatoid lung disease (Upper arm)
0.529 0.471 0.000
M05.11 Rheumatoid lung disease (Shoulder region)
0.529 0.471 0.000
M05.10 Rheumatoid lung disease (Multiple sites)
0.529 0.471 0.000
M35 Other systemic involvement of connective tissue
0.000 0.477 0.523
H15 Disorders of sclera
0.000 0.478 0.522
H47.2 Optic atrophy
0.000 0.479 0.521
M35.0 Sicca syndrome [Sjogren]
0.000 0.479 0.521
P90-P96 Other disorders originating in the perinatal period
0.000 0.479 0.520
P80-P83 Conditions involving the integument and temperature regulation of fetus and newborn
0.000 0.479 0.520
P75-P78 Digestive system disorders of fetus and newborn
0.000 0.479 0.520
P70-P74 Transitory endocrine and metabolic disorders specific to fetus and newborn
0.000 0.479 0.520
P50-P61 Haemorrhagic and haematological disorders of fetus and newborn
0.000 0.479 0.520
P35-P39 Infections specific to the perinatal period
0.000 0.479 0.520
P20-P29 Respiratory and cardiovascular disorders specific to the perinatal period
0.000 0.479 0.520
P05-P08 Disorders related to length of gestation and fetal growth
0.000 0.479 0.520
P00-P04 Fetus and newborn affected by maternal factors and by complications of pregnancy, labour and delivery
0.000 0.479 0.520
G36.9 Acute disseminated demyelination, unspecified
0.000 0.481 0.519
G36.8 Other specified acute disseminated demyelination
0.000 0.481 0.519
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.000 0.481 0.519
H03.8 Involvement of eyelid in other diseases classified elsewhere
0.000 0.481 0.518
H03.0 Parasitic infestation of eyelid in diseases classified elsewhere
0.000 0.481 0.518
L25.9 Unspecified contact dermatitis, unspecified cause
0.000 0.481 0.518
M35.3 Polymyalgia rheumatica
0.000 0.483 0.517
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
D81.9 Combined immunodeficiency, unspecified
0.000 0.486 0.514
D81.8 Other combined immunodeficiencies
0.000 0.486 0.514
D81.7 Major histocompatibility complex class II deficiency
0.000 0.486 0.514
D81.6 Major histocompatibility complex class I deficiency
0.000 0.486 0.514
D81.5 Purine nucleoside phosphorylase [PNP] deficiency
0.000 0.486 0.514
D81.4 Nezelof's syndrome
0.000 0.486 0.514
D81.3 Adenosine deaminase [ADA] deficiency
0.000 0.486 0.514
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers
0.000 0.486 0.514
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers
0.000 0.486 0.514
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis
0.000 0.486 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.513
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.513
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.513
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.513
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.513
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.513
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.513
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.513
H32.8 Other chorioretinal disorders in diseases classified elsewhere
0.000 0.487 0.513
H32.0 Chorioretinal inflammation in infectious and parasitic diseases classified elsewhere
0.000 0.487 0.513
D84.0 Lymphocyte function antigen-1 [LFA-1] defect
0.000 0.488 0.512
H26.3 Drug-induced cataract
0.000 0.489 0.511
L51.1 Bullous erythema multiforme
0.000 0.489 0.511
L30.8 Other specified dermatitis
0.000 0.490 0.510
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.000 0.491 0.509
H26.1 Traumatic cataract
0.000 0.491 0.509
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)
0.508 0.491 0.000
E04.2 Non-toxic multinodular goitre
0.000 0.492 0.508
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.002 0.492 0.505
M05.88 Other seropositive rheumatoid arthritis (Other)
0.506 0.493 0.000
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)
0.506 0.493 0.000
M05.86 Other seropositive rheumatoid arthritis (Lower leg)
0.506 0.493 0.000
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)
0.506 0.493 0.000
M05.84 Other seropositive rheumatoid arthritis (Hand)
0.506 0.493 0.000
M05.83 Other seropositive rheumatoid arthritis (Forearm)
0.506 0.493 0.000
M05.82 Other seropositive rheumatoid arthritis (Upper arm)
0.506 0.493 0.000
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)
0.506 0.493 0.000
M12 Other specific arthropathies
0.506 0.494 0.000
D52.8 Other folate deficiency anaemias
0.000 0.496 0.503
D52.1 Drug-induced folate deficiency anaemia
0.000 0.496 0.503
D52.0 Dietary folate deficiency anaemia
0.000 0.496 0.503
L62.8 Nail disorders in other diseases classified elsewhere
0.000 0.497 0.503
L62.0 Clubbed nail pachydermoperiostosis
0.000 0.497 0.503

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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