TreeWAS – Variant ID: rs927984

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K90.0 Coeliac disease	1.000	0.000	0.000
E83.1 Disorders of iron metabolism	0.000	0.001	0.999
Chapter IV Endocrine, nutritional and metabolic diseases	0.803	0.197	0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.798	0.202	0.000
O42 Premature rupture of membranes	0.797	0.203	0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.795	0.205	0.000
# Top node	0.785	0.215	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.783	0.217	0.000
O34 Maternal care for known or suspected abnormality of pelvic organs	0.783	0.217	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.778	0.222	0.000
E10-E14 Diabetes mellitus	0.778	0.222	0.000
D64.9 Anaemia, unspecified	0.777	0.223	0.000
O34.2 Maternal care due to uterine scar from previous surgery	0.776	0.224	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.776	0.224	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.773	0.227	0.000
D64 Other anaemias	0.771	0.229	0.000
D60-D64 Aplastic and other anaemias	0.769	0.231	0.000
E00-E07 Disorders of thyroid gland	0.769	0.231	0.000
Chapter V Mental and behavioural disorders	0.766	0.234	0.000
E10 Insulin-dependent diabetes mellitus	0.764	0.236	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.760	0.240	0.000
E10.9 Without complications	0.758	0.242	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.757	0.243	0.000
Q60-Q64 Congenital malformations of the urinary system	0.755	0.245	0.000
S90-S99 Injuries to the ankle and foot	0.754	0.246	0.000
E05.9 Thyrotoxicosis, unspecified	0.750	0.250	0.000
T66-T78 Other and unspecified effects of external causes	0.748	0.252	0.000
Q50-Q56 Congenital malformations of genital organs	0.748	0.252	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.747	0.253	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.740	0.260	0.000
K90 Intestinal malabsorption	0.737	0.263	0.000
Chapter XXII Codes for special purposes	0.732	0.268	0.000
Q61 Cystic kidney disease	0.730	0.270	0.000
F03 Unspecified dementia	0.729	0.271	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.727	0.273	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.726	0.274	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.725	0.275	0.000
O46 Antepartum haemorrhage, not elsewhere classified	0.721	0.279	0.000
D55-D59 Haemolytic anaemias	0.718	0.282	0.000
O41 Other disorders of amniotic fluid and membranes	0.717	0.283	0.000
Q50.4 Embryonic cyst of Fallopian tube	0.712	0.288	0.000
S20-S29 Injuries to the thorax	0.709	0.291	0.000
E70-E90 Metabolic disorders	0.709	0.291	0.000
E16 Other disorders of pancreatic internal secretion	0.708	0.292	0.000
E83 Disorders of mineral metabolism	0.686	0.294	0.021
S92 Fracture of foot, except ankle	0.699	0.301	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.697	0.303	0.000
F40-F48 Neurotic, stress-related and somatoform disorders	0.695	0.305	0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.689	0.311	0.000
F05 Delirium, not induced by alcohol and other psychoactive substances	0.687	0.313	0.000
T93 Sequelae of injuries of lower limb	0.680	0.320	0.000
F45 Somatoform disorders	0.679	0.321	0.000
T68 Hypothermia	0.678	0.322	0.000
E50-E64 Other nutritional deficiencies	0.673	0.327	0.000
E16.2 Hypoglycaemia, unspecified	0.673	0.327	0.000
E83.5 Disorders of calcium metabolism	0.672	0.327	0.001
U80 Agent resistant to penicillin and related antibiotics	0.668	0.332	0.000
T78 Adverse effects, not elsewhere classified	0.667	0.333	0.000
F45.8 Other somatoform disorders	0.664	0.336	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.664	0.336	0.000
Q61.3 Polycystic kidney, unspecified	0.663	0.337	0.000
S40-S49 Injuries to the shoulder and upper arm	0.662	0.338	0.000
O42.9 Premature rupture of membranes, unspecified	0.662	0.338	0.000
T93.8 Sequelae of other specified injuries of lower limb	0.660	0.340	0.000
E10.8 With unspecified complications	0.660	0.340	0.000
U80.1 Methicillin resistant agent	0.657	0.343	0.000
S21 Open wound of thorax	0.653	0.347	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.650	0.350	0.000
S92.3 Fracture of metatarsal bone	0.646	0.354	0.000
O20-O29 Other maternal disorders predominantly related to pregnancy	0.645	0.355	0.000
S93.1 Dislocation of toe(s)	0.644	0.356	0.000
E88 Other metabolic disorders	0.643	0.357	0.000
D56 Thalassaemia	0.643	0.357	0.000
O46.9 Antepartum haemorrhage, unspecified	0.639	0.361	0.000
S10-S19 Injuries to the neck	0.636	0.364	0.000
E14 Unspecified diabetes mellitus	0.635	0.365	0.000
T71 Asphyxiation	0.634	0.366	0.000
K90.9 Intestinal malabsorption, unspecified	0.634	0.366	0.000
T20 Burn and corrosion of head and neck	0.632	0.367	0.000
S93.0 Dislocation of ankle joint	0.632	0.368	0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.630	0.370	0.000
T23 Burn and corrosion of wrist and hand	0.629	0.371	0.000
F80-F89 Disorders of psychological development	0.628	0.372	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.627	0.373	0.000
O34.4 Maternal care for other abnormalities of cervix	0.626	0.374	0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.624	0.376	0.000
E20-E35 Disorders of other endocrine glands	0.621	0.379	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.618	0.382	0.000
E40-E46 Malnutrition	0.618	0.382	0.000
F05.9 Delirium, unspecified	0.616	0.384	0.000
O41.0 Oligohydramnios	0.613	0.387	0.000
Q61.9 Cystic kidney disease, unspecified	0.612	0.388	0.000
Q61.2 Polycystic kidney, adult type	0.609	0.391	0.000
S90 Superficial injury of ankle and foot	0.609	0.391	0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.608	0.392	0.000
S92.30 Fracture of metatarsal bone (closed)	0.608	0.392	0.000
O45 Premature separation of placenta [abruptio placentae]	0.608	0.392	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.606	0.394	0.000
E27 Other disorders of adrenal gland	0.605	0.395	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.605	0.395	0.000
S93.3 Dislocation of other and unspecified parts of foot	0.604	0.396	0.000
O34.3 Maternal care for cervical incompetence	0.603	0.397	0.000
T92 Sequelae of injuries of upper limb	0.603	0.397	0.000
Q39 Congenital malformations of oesophagus	0.600	0.400	0.000
F00 Dementia in Alzheimer's disease	0.599	0.401	0.000
E10.7 With multiple complications	0.598	0.402	0.000
F02 Dementia in other diseases classified elsewhere	0.598	0.402	0.000
E27.1 Primary adrenocortical insufficiency	0.595	0.405	0.000
E14.3 With ophthalmic complications	0.594	0.406	0.000
O44 Placenta praevia	0.590	0.410	0.000
O41.1 Infection of amniotic sac and membranes	0.586	0.413	0.000
O26 Maternal care for other conditions predominantly related to pregnancy	0.586	0.414	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.586	0.414	0.000
E04 Other non-toxic goitre	0.585	0.415	0.000
O46.8 Other antepartum haemorrhage	0.584	0.416	0.000
S43.0 Dislocation of shoulder joint	0.584	0.416	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.582	0.418	0.000
E55 Vitamin D deficiency	0.582	0.418	0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.582	0.418	0.000
T21 Burn and corrosion of trunk	0.582	0.418	0.000
T94 Sequelae of injuries involving multiple and unspecified body regions	0.579	0.421	0.000
D80-D89 Certain disorders involving the immune mechanism	0.578	0.422	0.000
Q60.0 Renal agenesis, unilateral	0.577	0.423	0.000
E73 Lactose intolerance	0.576	0.424	0.000
D59 Acquired haemolytic anaemia	0.576	0.424	0.000
F45.0 Somatisation disorder	0.575	0.425	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.574	0.426	0.000
S92.1 Fracture of talus	0.574	0.426	0.000
O31 Complications specific to multiple gestation	0.572	0.428	0.000
O43 Placental disorders	0.572	0.428	0.000
O42.2 Premature rupture of membranes, labour delayed by therapy	0.571	0.429	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.571	0.429	0.000
S20 Superficial injury of thorax	0.571	0.429	0.000
S29 Other and unspecified injuries of thorax	0.571	0.429	0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.570	0.429	0.000
F01 Vascular dementia	0.570	0.430	0.000
F23 Acute and transient psychotic disorders	0.570	0.430	0.000
E10.0 With coma	0.569	0.431	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.562	0.437	0.000
T90 Sequelae of injuries of head	0.562	0.438	0.000
S21.9 Open wound of thorax, part unspecified	0.562	0.438	0.000
E10.3 With ophthalmic complications	0.562	0.438	0.000
F44 Dissociative [conversion] disorders	0.562	0.438	0.000
Q35-Q37 Cleft lip and cleft palate	0.562	0.438	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.562	0.438	0.000
F05.0 Delirium not superimposed on dementia, so described	0.562	0.438	0.000
O34.9 Maternal care for abnormality of pelvic organ, unspecified	0.561	0.439	0.000
O34.6 Maternal care for abnormality of vagina	0.561	0.439	0.000
O34.5 Maternal care for other abnormalities of gravid uterus	0.561	0.439	0.000
O34.0 Maternal care for congenital malformation of uterus	0.561	0.439	0.000
Q61.0 Congenital single renal cyst	0.561	0.439	0.000
T78.0 Anaphylactic shock due to adverse food reaction	0.561	0.439	0.000
F80 Specific developmental disorders of speech and language	0.561	0.439	0.000
O26.9 Pregnancy-related condition, unspecified	0.560	0.440	0.000
T25 Burn and corrosion of ankle and foot	0.559	0.441	0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.559	0.441	0.000
O30 Multiple gestation	0.558	0.442	0.000
E12 Malnutrition-related diabetes mellitus	0.558	0.442	0.000
E83.4 Disorders of magnesium metabolism	0.552	0.442	0.005
O85-O92 Complications predominantly related to the puerperium	0.558	0.442	0.000
D58 Other hereditary haemolytic anaemias	0.557	0.443	0.000
O33 Maternal care for known or suspected disproportion	0.557	0.443	0.000
O34.7 Maternal care for abnormality of vulva and perineum	0.554	0.445	0.000
T33-T35 Frostbite	0.554	0.446	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.554	0.446	0.000
T70 Effects of air pressure and water pressure	0.554	0.446	0.000
D64.4 Congenital dyserythropoietic anaemia	0.553	0.447	0.000
D64.3 Other sideroblastic anaemias	0.553	0.447	0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.553	0.447	0.000
D64.1 Secondary sideroblastic anaemia due to disease	0.553	0.447	0.000
D64.0 Hereditary sideroblastic anaemia	0.553	0.447	0.000
O32 Maternal care for known or suspected malpresentation of foetus	0.553	0.447	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.551	0.449	0.000
S92.4 Fracture of great toe	0.551	0.449	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.551	0.449	0.000
E00 Congenital iodine-deficiency syndrome	0.551	0.449	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.551	0.449	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.550	0.450	0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.550	0.450	0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.550	0.450	0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.549	0.451	0.000
T93.2 Sequelae of other fractures of lower limb	0.549	0.451	0.000
S49 Other and unspecified injuries of shoulder and upper arm	0.548	0.452	0.000
Q51 Congenital malformations of uterus and cervix	0.548	0.452	0.000
E07 Other disorders of thyroid	0.547	0.453	0.000
E04.9 Non-toxic goitre, unspecified	0.547	0.453	0.000
D64.8 Other specified anaemias	0.546	0.453	0.000
E05.8 Other thyrotoxicosis	0.545	0.455	0.000
E05.5 Thyroid crisis or storm	0.545	0.455	0.000
E05.4 Thyrotoxicosis factitia	0.545	0.455	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.545	0.455	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.545	0.455	0.000
T78.2 Anaphylactic shock, unspecified	0.545	0.455	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.545	0.455	0.000
T92.9 Sequelae of unspecified injury of upper limb	0.544	0.456	0.000
D56.3 Thalassaemia trait	0.544	0.456	0.000
D56.1 Beta thalassaemia	0.544	0.456	0.000
S21.1 Open wound of front wall of thorax	0.544	0.456	0.000
T00-T07 Injuries involving multiple body regions	0.543	0.457	0.000
F09 Unspecified organic or symptomatic mental disorder	0.543	0.457	0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.543	0.457	0.000
O41.8 Other specified disorders of amniotic fluid and membranes	0.542	0.457	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.541	0.459	0.000
S98 Traumatic amputation of ankle and foot	0.541	0.459	0.000
S97 Crushing injury of ankle and foot	0.541	0.459	0.000
S95 Injury of blood vessels at ankle and foot level	0.541	0.459	0.000
S94 Injury of nerves at ankle and foot level	0.541	0.459	0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.541	0.459	0.000
E53 Deficiency of other B group vitamins	0.540	0.460	0.000
T74 Maltreatment syndromes	0.537	0.463	0.000
T73 Effects of other deprivation	0.537	0.463	0.000
T69 Other effects of reduced temperature	0.537	0.463	0.000
T67 Effects of heat and light	0.537	0.463	0.000
Q56 Indeterminate sex and pseudohermaphroditism	0.536	0.464	0.000
Q55 Other congenital malformations of male genital organs	0.536	0.464	0.000
Q52 Other congenital malformations of female genitalia	0.536	0.464	0.000
E15 Nondiabetic hypoglycaemic coma	0.536	0.464	0.000
O47 False labour	0.536	0.464	0.000
E10.1 With ketoacidosis	0.535	0.465	0.000
F99-F99 Unspecified mental disorder	0.534	0.466	0.000
E27.2 Addisonian crisis	0.534	0.466	0.000
K90.8 Other intestinal malabsorption	0.532	0.468	0.000
Q43 Other congenital malformations of intestine	0.531	0.469	0.000
S19 Other and unspecified injuries of neck	0.530	0.470	0.000
Q53 Undescended testicle	0.529	0.471	0.000
K90.3 Pancreatic steatorrhoea	0.528	0.472	0.000
K90.2 Blind loop syndrome, not elsewhere classified	0.528	0.472	0.000
K90.1 Tropical sprue	0.528	0.472	0.000
T20.1 Burn of first degree of head and neck	0.528	0.472	0.000
Q64 Other congenital malformations of urinary system	0.528	0.472	0.000
Q40 Other congenital malformations of upper alimentary tract	0.526	0.474	0.000
Q00-Q07 Congenital malformations of the nervous system	0.526	0.474	0.000
T22.2 Burn of second degree of shoulder and upper limb, except wrist and hand	0.525	0.475	0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.524	0.476	0.000
Q61.8 Other cystic kidney diseases	0.523	0.477	0.000
Q61.4 Renal dysplasia	0.523	0.477	0.000
Q61.1 Polycystic kidney, infantile type	0.523	0.477	0.000
T79-T79 Certain early complications of trauma	0.523	0.477	0.000
D50-D53 Nutritional anaemias	0.523	0.477	0.000
Q28 Other congenital malformations of circulatory system	0.522	0.478	0.000
E10.6 With other specified complications	0.522	0.478	0.000
Q60.2 Renal agenesis, unspecified	0.522	0.478	0.000
T23.2 Burn of second degree of wrist and hand	0.522	0.478	0.000
Q50.6 Other congenital malformatons of Fallopian tube and broad ligament	0.521	0.479	0.000
Q50.5 Embryonic cyst of broad ligament	0.521	0.479	0.000
Q50.3 Other congenital malformations of ovary	0.521	0.479	0.000
Q50.2 Congenital torsion of ovary	0.521	0.479	0.000
Q50.1 Developmental ovarian cyst	0.521	0.479	0.000
Q50.0 Congenital absence of ovary	0.521	0.479	0.000
T95 Sequelae of burns, corrosions and frostbite	0.521	0.479	0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.521	0.479	0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.521	0.479	0.000
Q39.4 Oesophageal web	0.520	0.480	0.000
T66 Unspecified effects of radiation	0.520	0.480	0.000
S93.4 Sprain and strain of ankle	0.520	0.480	0.000
S93.6 Sprain and strain of other and unspecified parts of foot	0.520	0.480	0.000
S93.5 Sprain and strain of toe(s)	0.520	0.480	0.000
S93.2 Rupture of ligaments at ankle and foot level	0.520	0.480	0.000
T78.8 Other adverse effects, not elsewhere classified	0.517	0.482	0.000
O46.0 Antepartum haemorrhage with coagulation defect	0.517	0.483	0.000
E55.9 Vitamin D deficiency, unspecified	0.517	0.483	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.517	0.483	0.000
Q61.5 Medullary cystic kidney	0.516	0.484	0.000
T16 Foreign body in ear	0.515	0.485	0.000
D57 Sickle-cell disorders	0.515	0.485	0.000
D55 Anaemia due to enzyme disorders	0.515	0.485	0.000
O41.9 Disorder of amniotic fluid and membranes, unspecified	0.514	0.486	0.000
S92.2 Fracture of other tarsal bone(s)	0.513	0.486	0.000
S21.2 Open wound of back wall of thorax	0.513	0.487	0.000
F05.8 Other delirium	0.513	0.487	0.000
F80.1 Expressive language disorder	0.512	0.488	0.000
F42 Obsessive-compulsive disorder	0.511	0.488	0.000
S46 Injury of muscle and tendon at shoulder and upper arm level	0.511	0.489	0.000
S92.7 Multiple fractures of foot	0.509	0.491	0.000
S27 Injury of other and unspecified intrathoracic organs	0.509	0.491	0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.508	0.492	0.000
S26 Injury of heart	0.508	0.492	0.000
S25 Injury of blood vessels of thorax	0.508	0.492	0.000
S24 Injury of nerves and spinal cord at thorax level	0.508	0.492	0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.508	0.492	0.000
E84 Cystic fibrosis	0.508	0.492	0.000
E79 Disorders of purine and pyrimidine metabolism	0.508	0.492	0.000
E77 Disorders of glycoprotein metabolism	0.508	0.492	0.000
E76 Disorders of glycosaminoglycan metabolism	0.508	0.492	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.508	0.492	0.000
E72 Other disorders of amino-acid metabolism	0.508	0.492	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.508	0.492	0.000
E70 Disorders of aromatic amino-acid metabolism	0.508	0.492	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.508	0.492	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.507	0.492	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.507	0.492	0.000
E16.4 Abnormal secretion of gastrin	0.507	0.492	0.000
E16.3 Increased secretion of glucagon	0.507	0.492	0.000
Q45 Other congenital malformations of digestive system	0.507	0.493	0.000
E83.9 Disorder of mineral metabolism, unspecified	0.492	0.493	0.015
E83.8 Other disorders of mineral metabolism	0.492	0.493	0.015
E83.2 Disorders of zinc metabolism	0.492	0.493	0.015
E83.0 Disorders of copper metabolism	0.492	0.493	0.015
S90.0 Contusion of ankle	0.506	0.494	0.000
T93.1 Sequelae of fracture of femur	0.506	0.494	0.000
E16.1 Other hypoglycaemia	0.506	0.494	0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.505	0.495	0.000
O21 Excessive vomiting in pregnancy	0.505	0.495	0.000
S43.5 Sprain and strain of acromioclavicular joint	0.504	0.496	0.000
O22 Venous complications in pregnancy	0.503	0.497	0.000
E24 Cushing's syndrome	0.502	0.498	0.000
S92.9 Fracture of foot, unspecified	0.501	0.498	0.000
F70-F79 Mental retardation	0.501	0.499	0.000
S14 Injury of nerves and spinal cord at neck level	0.501	0.499	0.000
T20.2 Burn of second degree of head and neck	0.500	0.500	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.500	0.500	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.500	0.500	0.000
T23.1 Burn of first degree of wrist and hand	0.499	0.500	0.000
D61 Other aplastic anaemias	0.499	0.501	0.000
T78.1 Other adverse food reactions, not elsewhere classified	0.498	0.502	0.000
Q27 Other congenital malformations of peripheral vascular system	0.498	0.502	0.000
T78.3 Angioneurotic oedema	0.498	0.502	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.496	0.503	0.000
T22.3 Burn of third degree of shoulder and upper limb, except wrist and hand	0.495	0.505	0.000
E31 Polyglandular dysfunction	0.495	0.505	0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.495	0.505	0.000
Q17 Other congenital malformations of ear	0.494	0.506	0.000
E74 Other disorders of carbohydrate metabolism	0.494	0.506	0.000
U50 Level of care administered to neonates	0.494	0.506	0.000
U07 Emergency use of U07	0.494	0.506	0.000
U06 Emergency use of U06	0.494	0.506	0.000
U04 Severe acute respiratory syndrome [SARS]	0.494	0.506	0.000
U52 First in a series of a regular day/night admissions	0.494	0.506	0.000
T75 Effects of other external causes	0.493	0.507	0.000
U51 Admission status on psychiatric patients	0.493	0.507	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.490	0.510	0.000
F23.0 Acute polymorphic psychotic disorder without symptoms of schizophrenia	0.490	0.510	0.000
O44.1 Placenta praevia with haemorrhage	0.490	0.510	0.000
O47.0 False labour before 37 completed weeks of gestation	0.490	0.510	0.000
T23.3 Burn of third degree of wrist and hand	0.490	0.510	0.000
O28 Abnormal findings on antenatal screening of mother	0.488	0.511	0.000
T90.4 Sequelae of injury of eye and orbit	0.488	0.512	0.000
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.488	0.512	0.000
T93.4 Sequelae of injury of nerve of lower limb	0.488	0.512	0.000
F45.4 Persistent somatoform pain disorder	0.487	0.513	0.000
F45.2 Hypochondriacal disorder	0.487	0.513	0.000
F45.1 Undifferentiated somatoform disorder	0.487	0.513	0.000
S99 Other and unspecified injuries of ankle and foot	0.486	0.514	0.000
F23.9 Acute and transient psychotic disorder, unspecified	0.486	0.514	0.000
O35 Maternal care for known or suspected foetal abnormality and damage	0.486	0.514	0.000
E46 Unspecified protein-energy malnutrition	0.485	0.515	0.000
S92.10 Fracture of talus (closed)	0.484	0.515	0.000
Q54 Hypospadias	0.484	0.516	0.000
F60-F69 Disorders of adult personality and behaviour	0.484	0.516	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.483	0.517	0.000
E63 Other nutritional deficiencies	0.483	0.517	0.000
E56 Other vitamin deficiencies	0.483	0.517	0.000
E51 Thiamine deficiency	0.483	0.517	0.000
E50 Vitamin A deficiency	0.483	0.517	0.000
E60 Dietary zinc deficiency	0.483	0.517	0.000
E59 Dietary selenium deficiency	0.483	0.517	0.000
E58 Dietary calcium deficiency	0.483	0.517	0.000
E54 Ascorbic acid deficiency	0.483	0.517	0.000
E52 Niacin deficiency [pellagra]	0.483	0.517	0.000
E73.9 Lactose intolerance, unspecified	0.481	0.519	0.000
S20.2 Contusion of thorax	0.481	0.519	0.000
O80-O84 Delivery	0.480	0.520	0.000
F20 Schizophrenia	0.478	0.522	0.000
T78.9 Adverse effect, unspecified	0.478	0.522	0.000
Q18 Other congenital malformations of face and neck	0.478	0.522	0.000
S70-S79 Injuries to the hip and thigh	0.477	0.523	0.000
E13 Other specified diabetes mellitus	0.476	0.523	0.000
E88.8 Other specified metabolic disorders	0.476	0.523	0.000
F45.9 Somatoform disorder, unspecified	0.476	0.524	0.000
Q60.6 Potter's syndrome	0.476	0.524	0.000
Q60.5 Renal hypoplasia, unspecified	0.476	0.524	0.000
Q60.4 Renal hypoplasia, bilateral	0.476	0.524	0.000
Q60.3 Renal hypoplasia, unilateral	0.476	0.524	0.000
Q60.1 Renal agenesis, bilateral	0.476	0.524	0.000
O34.8 Maternal care for other abnormalities of pelvic organs	0.476	0.524	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.475	0.524	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.475	0.525	0.000
S48 Traumatic amputation of shoulder and upper arm	0.475	0.525	0.000
S45 Injury of blood vessels at shoulder and upper arm level	0.475	0.525	0.000
S44 Injury of nerves at shoulder and upper arm level	0.475	0.525	0.000
S47 Crushing injury of shoulder and upper arm	0.475	0.525	0.000
Q15 Other congenital malformations of eye	0.474	0.525	0.000
S92.5 Fracture of other toe	0.474	0.526	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.473	0.527	0.000
T94.1 Sequelae of injuries, not specified by body region	0.473	0.527	0.000
S29.9 Unspecified injury of thorax	0.472	0.528	0.000
F02.0 Dementia in Pick's disease	0.471	0.529	0.000
E14.6 With other specified complications	0.471	0.529	0.000
O45.9 Premature separation of placenta, unspecified	0.471	0.529	0.000
D80 Immunodeficiency with predominantly antibody defects	0.470	0.530	0.000
E10.5 With peripheral circulatory complications	0.470	0.530	0.000
F48 Other neurotic disorders	0.469	0.531	0.000
S21.8 Open wound of other parts of thorax	0.468	0.532	0.000
S21.7 Multiple open wounds of thoracic wall	0.468	0.532	0.000
S21.0 Open wound of breast	0.468	0.532	0.000
S43.4 Sprain and strain of shoulder joint	0.468	0.532	0.000
F44.0 Dissociative amnesia	0.468	0.532	0.000
O32.1 Maternal care for breech presentation	0.467	0.533	0.000
F43 Reaction to severe stress, and adjustment disorders	0.467	0.533	0.000
Chapter VII Diseases of the eye and adnexa	0.467	0.533	0.000
S49.9 Unspecified injury of shoulder and upper arm	0.467	0.533	0.000
D59.9 Acquired haemolytic anaemia, unspecified	0.466	0.534	0.000
F29 Unspecified nonorganic psychosis	0.466	0.534	0.000
E11 Non-insulin-dependent diabetes mellitus	0.464	0.536	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.464	0.536	0.000
Q80-Q89 Other congenital malformations	0.464	0.536	0.000
S92.31 Fracture of metatarsal bone (open)	0.463	0.537	0.000
O29 Complications of anaesthesia during pregnancy	0.463	0.537	0.000
O25 Malnutrition in pregnancy	0.463	0.537	0.000
F50 Eating disorders	0.462	0.538	0.000
S90.3 Contusion of other and unspecified parts of foot	0.462	0.538	0.000
L20-L30 Dermatitis and eczema	0.462	0.538	0.000
U80.8 Agent resistant to other penicillin-related antibiotic	0.461	0.538	0.000
E14.4 With neurological complications	0.461	0.539	0.000
E88.9 Metabolic disorder, unspecified	0.461	0.539	0.000
E88.3 Tumour lysis syndrome	0.461	0.539	0.000
E88.1 Lipodystrophy, not elsewhere classified	0.461	0.539	0.000
D56.9 Thalassaemia, unspecified	0.461	0.539	0.000
D56.8 Other thalassaemias	0.461	0.539	0.000
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]	0.461	0.539	0.000
D56.2 Delta-beta thalassaemia	0.461	0.539	0.000
D56.0 Alpha thalassaemia	0.461	0.539	0.000
S11 Open wound of neck	0.459	0.541	0.000
Q28.2 Arteriovenous malformation of cerebral vessels	0.459	0.541	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.459	0.541	0.000
S19.9 Unspecified injury of neck	0.458	0.542	0.000
F00.9 Dementia in Alzheimer's disease, unspecified	0.458	0.542	0.000
S17 Crushing injury of neck	0.456	0.544	0.000
S15 Injury of blood vessels at neck level	0.456	0.544	0.000
S18 Traumatic amputation at neck level	0.456	0.544	0.000
S16 Injury of muscle and tendon at neck level	0.456	0.544	0.000
E14.7 With multiple complications	0.455	0.544	0.000
E14.5 With peripheral circulatory complications	0.455	0.544	0.000
E14.2 Withrenal complications	0.455	0.544	0.000
E14.1 With ketoacidosis	0.455	0.544	0.000
E14.0 With coma	0.455	0.544	0.000
Q44.6 Cystic disease of liver	0.455	0.545	0.000
Q44.5 Other congenital malformations of bile ducts	0.455	0.545	0.000
O92 Other disorders of breast and lactation associated with childbirth	0.455	0.545	0.000
E11.5 With peripheral circulatory complications	0.455	0.545	0.000
T20.7 Corrosion of third degree of head and neck	0.453	0.546	0.000
T20.6 Corrosion of second degree of head and neck	0.453	0.546	0.000
T20.5 Corrosion of first degree of head and neck	0.453	0.546	0.000
T20.4 Corrosion of unspecified degree of head and neck	0.453	0.546	0.000
T20.3 Burn of third degree of head and neck	0.453	0.546	0.000
T20.0 Burn of unspecified degree of head and neck	0.453	0.546	0.000
S90.8 Other superficial injuries of ankle and foot	0.453	0.547	0.000
T21.2 Burn of second degree of trunk	0.452	0.547	0.000
T22.7 Corrosion of third degree of shoulder and upper limb, except wrist and hand	0.452	0.548	0.000
T22.6 Corrosion of second degree of shoulder and upper limb, except wrist and hand	0.452	0.548	0.000
T22.5 Corrosion of first degree of shoulder and upper limb, except wrist and hand	0.452	0.548	0.000
T22.4 Corrosion of unspecified degree of shoulder and upper limb, except wrist and hand	0.452	0.548	0.000
T22.1 Burn of first degree of shoulder and upper limb, except wrist and hand	0.452	0.548	0.000
T22.0 Burn of unspecified degree of shoulder and upper limb, except wrist and hand	0.452	0.548	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.451	0.549	0.000
T23.7 Corrosion of third degree of wrist and hand	0.451	0.549	0.000
T23.6 Corrosion of second degree of wrist and hand	0.451	0.549	0.000
T23.5 Corrosion of first degree of wrist and hand	0.451	0.549	0.000
T23.4 Corrosion of unspecified degree of wrist and hand	0.451	0.549	0.000
D62 Acute posthaemorrhagic anaemia	0.451	0.549	0.000
F05.1 Delirium superimposed on dementia	0.450	0.549	0.000
D84 Other immunodeficiencies	0.450	0.549	0.000
Q39.6 Diverticulum of oesophagus	0.450	0.549	0.000
F89 Unspecified disorder of psychological development	0.450	0.550	0.000
F88 Other disorders of psychological development	0.450	0.550	0.000
F83 Mixed specific developmental disorders	0.450	0.550	0.000
F82 Specific developmental disorder of motor function	0.450	0.550	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.450	0.550	0.000
F28 Other nonorganic psychotic disorders	0.450	0.550	0.000
F24 Induced delusional disorder	0.450	0.550	0.000
F21 Schizotypal disorder	0.450	0.550	0.000
D52 Folate deficiency anaemia	0.450	0.550	0.000
F00.0 Dementia in Alzheimer's disease with early onset	0.450	0.550	0.000
O32.3 Maternal care for face, brow and chin presentation	0.450	0.550	0.000
O26.2 Pregnancy care of habitual aborter	0.448	0.552	0.000
S43.7 Sprain and strain of other and unspecified parts of shoulder girdle	0.447	0.553	0.000
S43.6 Sprain and strain of sternoclavicular joint	0.447	0.553	0.000
S43.3 Dislocation of other and unspecified parts of shoulder girdle	0.447	0.553	0.000
S43.2 Dislocation of sternoclavicular joint	0.447	0.553	0.000
U80.0 Penicillin resistant agent	0.447	0.553	0.000
D63 Anaemia in chronic diseases classified elsewhere	0.447	0.553	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.446	0.554	0.000
T19 Foreign body in genito-urinary tract	0.446	0.554	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.445	0.555	0.000
E32 Diseases of thymus	0.445	0.555	0.000
E30 Disorders of puberty, not elsewhere classified	0.445	0.555	0.000
E25 Adrenogenital disorders	0.445	0.555	0.000
F00.2 Dementia in Alzheimer's disease, atypical or mixed type	0.444	0.556	0.000
Q51.3 Bicornate uterus	0.444	0.556	0.000
Q16 Congenital malformations of ear causing impairment of hearing	0.443	0.557	0.000
Q14 Congenital malformations of posterior segment of eye	0.443	0.557	0.000
Q13 Congenital malformations of anterior segment of eye	0.443	0.557	0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos	0.443	0.557	0.000
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit	0.443	0.557	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.443	0.557	0.000
E45 Retarded development following protein-energy malnutrition	0.443	0.557	0.000
E43 Unspecified severe protein-energy malnutrition	0.443	0.557	0.000
E42 Marasmic kwashiorkor	0.443	0.557	0.000
E41 Nutritional marasmus	0.443	0.557	0.000
E40 Kwashiorkor	0.443	0.557	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations