TreeWAS – Variant ID: rs9286879

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Showing all nodes without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E53.8 Deficiency of other specified B group vitamins	0.091	0.909	0.000
E53 Deficiency of other B group vitamins	0.065	0.935	0.000
E53.9 Vitamin B deficiency, unspecified	0.050	0.950	0.000
E53.1 Pyridoxine deficiency	0.047	0.953	0.000
E53.0 Riboflavin deficiency	0.047	0.953	0.000
Z91.5 Personal history of self-harm	0.000	0.956	0.044
H00.1 Chalazion	0.044	0.956	0.000
Z91.6 Personal history of other physical trauma	0.000	0.958	0.042
E50-E64 Other nutritional deficiencies	0.041	0.959	0.000
Z91 Personal history of risk-factors, not elsewhere classified	0.000	0.960	0.040
Z91.8 Personal history of other specified risk-factors, not elsewhere classified	0.000	0.966	0.034
E58 Dietary calcium deficiency	0.033	0.967	0.000
Z91.2 Personal history of poor personal hygiene	0.000	0.968	0.032
E61 Deficiency of other nutrient elements	0.031	0.969	0.000
E56 Other vitamin deficiencies	0.030	0.970	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.029	0.970	0.000
E63 Other nutritional deficiencies	0.029	0.970	0.000
E50 Vitamin A deficiency	0.029	0.970	0.000
E60 Dietary zinc deficiency	0.029	0.970	0.000
E59 Dietary selenium deficiency	0.029	0.970	0.000
E54 Ascorbic acid deficiency	0.029	0.970	0.000
E52 Niacin deficiency [pellagra]	0.029	0.970	0.000
Z91.7 Personal history of female genital mutilation	0.000	0.971	0.029
Z91.3 Personal history of unhealthy sleep-wake schedule	0.000	0.971	0.029
E51 Thiamine deficiency	0.027	0.972	0.000
E16.2 Hypoglycaemia, unspecified	0.028	0.972	0.000
E22 Hyperfunction of pituitary gland	0.026	0.974	0.000
E55 Vitamin D deficiency	0.026	0.974	0.000
T81.8 Other complications of procedures, not elsewhere classified	0.000	0.974	0.026
E20-E35 Disorders of other endocrine glands	0.026	0.974	0.000
Z91.4 Personal history of psychological trauma, not elsewhere classified	0.000	0.975	0.025
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.025	0.975	0.000
E27 Other disorders of adrenal gland	0.025	0.975	0.000
E16 Other disorders of pancreatic internal secretion	0.024	0.976	0.000
E27.9 Disorder of adrenal gland, unspecified	0.023	0.977	0.000
E61.2 Magnesium deficiency	0.023	0.977	0.000
Z91.0 Personal history of allergy, other than to drugs and biological substances	0.000	0.977	0.023
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.023	0.977	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.023	0.977	0.000
E61.1 Iron deficiency	0.022	0.977	0.000
E61.9 Deficiency of nutrient element, unspecified	0.022	0.978	0.000
E61.8 Deficiency of other specified nutrient elements	0.022	0.978	0.000
E61.7 Deficiency of multiple nutrient elements	0.022	0.978	0.000
E61.6 Vanadium deficiency	0.022	0.978	0.000
E61.5 Molybdenum deficiency	0.022	0.978	0.000
E61.4 Chromium deficiency	0.022	0.978	0.000
E61.3 Manganese deficiency	0.022	0.978	0.000
E61.0 Copper deficiency	0.022	0.978	0.000
E22.1 Hyperprolactinaemia	0.022	0.978	0.000
E22.0 Acromegaly and pituitary gigantism	0.022	0.978	0.000
E56.1 Deficiency of vitamin K	0.022	0.978	0.000
E26 Hyperaldosteronism	0.022	0.978	0.000
E56.9 Vitamin deficiency, unspecified	0.021	0.978	0.000
E56.8 Deficiency of other vitamins	0.021	0.978	0.000
E56.0 Deficiency of vitamin E	0.021	0.978	0.000
E50.9 Vitamin A deficiency, unspecified	0.021	0.979	0.000
E50.8 Other manifestations of vitamin A deficiency	0.021	0.979	0.000
E50.7 Other ocular manifestations of vitamin A deficiency	0.021	0.979	0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.021	0.979	0.000
E50.5 Vitamin A deficiency with night blindness	0.021	0.979	0.000
E50.4 Vitamin A deficiency with keratomalacia	0.021	0.979	0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.021	0.979	0.000
E50.2 Vitamin A deficiency with corneal xerosis	0.021	0.979	0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.021	0.979	0.000
E50.0 Vitamin A deficiency with conjunctival xerosis	0.021	0.979	0.000
E63.9 Nutritional deficiency, unspecified	0.021	0.979	0.000
E63.8 Other specified nutritional deficiencies	0.021	0.979	0.000
E63.1 Imbalance of constituents of food intake	0.021	0.979	0.000
E63.0 Essential fatty acid [EFA] deficiency	0.021	0.979	0.000
E64.9 Sequelae of unspecified nutritional deficiency	0.021	0.979	0.000
E64.8 Sequelae of other nutritional deficiencies	0.021	0.979	0.000
E64.3 Sequelae of rickets	0.021	0.979	0.000
E64.2 Sequelae of vitamin C deficiency	0.021	0.979	0.000
E64.1 Sequelae of vitamin A deficiency	0.021	0.979	0.000
E64.0 Sequelae of protein-energy malnutrition	0.021	0.979	0.000
Z91.1 Personal history of noncompliance with medical treatment and regimen	0.000	0.979	0.021
E51.9 Thiamine deficiency, unspecified	0.020	0.980	0.000
E51.8 Other manifestations of thiamine deficiency	0.020	0.980	0.000
E51.1 Beriberi	0.020	0.980	0.000
E29 Testicular dysfunction	0.020	0.980	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.020	0.980	0.000
E25 Adrenogenital disorders	0.020	0.980	0.000
E24 Cushing's syndrome	0.019	0.981	0.000
E27.2 Addisonian crisis	0.019	0.981	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.019	0.981	0.000
E22.8 Other hyperfunction of pituitary gland	0.019	0.981	0.000
E31 Polyglandular dysfunction	0.019	0.981	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.019	0.981	0.000
I77.1 Stricture of artery	0.000	0.981	0.019
I77.8 Other specified disorders of arteries and arterioles	0.000	0.981	0.019
E27.1 Primary adrenocortical insufficiency	0.019	0.981	0.000
E55.0 Rickets, active	0.019	0.981	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.019	0.981	0.000
E32 Diseases of thymus	0.019	0.981	0.000
E30 Disorders of puberty, not elsewhere classified	0.019	0.981	0.000
E51.2 Wernicke's encephalopathy	0.018	0.982	0.000
E27.5 Adrenomedullary hyperfunction	0.018	0.982	0.000
E27.0 Other adrenocortical overactivity	0.018	0.982	0.000
E26.0 Primary hyperaldosteronism	0.018	0.982	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.017	0.982	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.017	0.982	0.000
E16.4 Abnormal secretion of gastrin	0.017	0.982	0.000
E16.3 Increased secretion of glucagon	0.017	0.982	0.000
E26.9 Hyperaldosteronism, unspecified	0.017	0.982	0.000
E27.8 Other specified disorders of adrenal gland	0.017	0.983	0.000
I77 Other disorders of arteries and arterioles	0.000	0.983	0.017
E20 Hypoparathyroidism	0.017	0.983	0.000
E28 Ovarian dysfunction	0.017	0.983	0.000
E15 Nondiabetic hypoglycaemic coma	0.017	0.983	0.000
M54.99 Dorsalgia, unspecified (Site unspecified)	0.000	0.983	0.017
E23 Hypofunction and other disorders of pituitary gland	0.016	0.984	0.000
E29.1 Testicular hypofunction	0.016	0.984	0.000
E26.8 Other hyperaldosteronism	0.016	0.984	0.000
E26.1 Secondary hyperaldosteronism	0.016	0.984	0.000
E24.8 Other Cushing's syndrome	0.016	0.984	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.016	0.984	0.000
E16.1 Other hypoglycaemia	0.016	0.984	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.015	0.984	0.000
E34 Other endocrine disorders	0.015	0.985	0.000
K51.9 Ulcerative colitis, unspecified	0.000	0.985	0.015
E24.9 Cushing's syndrome, unspecified	0.015	0.985	0.000
E55.9 Vitamin D deficiency, unspecified	0.015	0.985	0.000
E29.9 Testicular dysfunction, unspecified	0.014	0.985	0.000
E29.8 Other testicular dysfunction	0.014	0.985	0.000
E29.0 Testicular hyperfunction	0.014	0.985	0.000
E40-E46 Malnutrition	0.014	0.985	0.000
E25.9 Adrenogenital disorder, unspecified	0.014	0.985	0.000
E25.8 Other adrenogenital disorders	0.014	0.985	0.000
E31.0 Autoimmune polyglandular failure	0.014	0.986	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.014	0.986	0.000
E24.3 Ectopic ACTH syndrome	0.014	0.986	0.000
E24.1 Nelson's syndrome	0.014	0.986	0.000
E31.9 Polyglandular dysfunction, unspecified	0.014	0.986	0.000
E31.8 Other polyglandular dysfunction	0.014	0.986	0.000
E31.1 Polyglandular hyperfunction	0.014	0.986	0.000
I77.2 Rupture of artery	0.000	0.986	0.014
K57.2 Diverticular disease of large intestine with perforation and abscess	0.014	0.986	0.000
E30.9 Disorder of puberty, unspecified	0.013	0.986	0.000
E30.8 Other disorders of puberty	0.013	0.986	0.000
E30.1 Precocious puberty	0.013	0.986	0.000
E30.0 Delayed puberty	0.013	0.986	0.000
E32.9 Disease of thymus, unspecified	0.013	0.986	0.000
E32.8 Other diseases of thymus	0.013	0.986	0.000
E32.1 Abscess of thymus	0.013	0.986	0.000
E32.0 Persistent hyperplasia of thymus	0.013	0.986	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.013	0.986	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.013	0.986	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.013	0.986	0.000
E24.0 Pituitary-dependent Cushing's disease	0.013	0.987	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.013	0.987	0.000
I77.9 Disorder of arteries and arterioles, unspecified	0.000	0.987	0.013
E20.8 Other hypoparathyroidism	0.013	0.987	0.000
E20.1 Pseudohypoparathyroidism	0.013	0.987	0.000
E20.0 Idiopathic hypoparathyroidism	0.013	0.987	0.000
I77.5 Necrosis of artery	0.000	0.987	0.013
I77.4 Coeliac artery compression syndrome	0.000	0.987	0.013
I77.3 Arterial fibromuscular dysplasia	0.000	0.987	0.013
E28.2 Polycystic ovarian syndrome	0.013	0.987	0.000
E28.9 Ovarian dysfunction, unspecified	0.012	0.987	0.000
E28.8 Other ovarian dysfunction	0.012	0.987	0.000
E28.1 Androgen excess	0.012	0.987	0.000
E28.0 Oestrogen excess	0.012	0.987	0.000
I77.6 Arteritis, unspecified	0.000	0.987	0.012
E24.2 Drug-induced Cushing's syndrome	0.012	0.988	0.000
I77.0 Arteriovenous fistula, acquired	0.000	0.988	0.012
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.012	0.988	0.000
E23.1 Drug-induced hypopituitarism	0.012	0.988	0.000
E23.0 Hypopituitarism	0.012	0.988	0.000
E23.6 Other disorders of pituitary gland	0.011	0.988	0.000
E20.9 Hypoparathyroidism, unspecified	0.011	0.989	0.000
E23.7 Disorder of pituitary gland, unspecified	0.011	0.989	0.000
E34.5 Androgen resistance syndrome	0.011	0.989	0.000
E34.4 Constitutional tall stature	0.011	0.989	0.000
E34.3 Short stature, not elsewhere classified	0.011	0.989	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.011	0.989	0.000
E34.1 Other hypersecretion of intestinal hormones	0.011	0.989	0.000
E34.8 Other specified endocrine disorders	0.011	0.989	0.000
E23.2 Diabetes insipidus	0.011	0.989	0.000
E28.3 Primary ovarian failure	0.011	0.989	0.000
E21.2 Other hyperparathyroidism	0.011	0.989	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.011	0.989	0.000
E45 Retarded development following protein-energy malnutrition	0.011	0.989	0.000
E43 Unspecified severe protein-energy malnutrition	0.011	0.989	0.000
E42 Marasmic kwashiorkor	0.011	0.989	0.000
E41 Nutritional marasmus	0.011	0.989	0.000
E40 Kwashiorkor	0.011	0.989	0.000
H00 Hordeolum and chalazion	0.010	0.990	0.000
E34.9 Endocrine disorder, unspecified	0.010	0.990	0.000
E34.0 Carcinoid syndrome	0.010	0.990	0.000
J39.2 Other diseases of pharynx	0.010	0.990	0.000
E65-E68 Obesity and other hyperalimentation	0.010	0.990	0.000
E21.4 Other specified disorders of parathyroid gland	0.009	0.990	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.009	0.991	0.000
E46 Unspecified protein-energy malnutrition	0.009	0.991	0.000
M54.22 Cervicalgia (Cervical region)	0.000	0.991	0.009
Z98.1 Arthrodesis status	0.008	0.992	0.000
E44.1 Mild protein-energy malnutrition	0.008	0.992	0.000
E44.0 Moderate protein-energy malnutrition	0.008	0.992	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.008	0.992	0.000
E21.0 Primary hyperparathyroidism	0.007	0.993	0.000
E67 Other hyperalimentation	0.007	0.993	0.000
E68 Sequelae of hyperalimentation	0.007	0.993	0.000
E65 Localised adiposity	0.007	0.993	0.000
E21.3 Hyperparathyroidism, unspecified	0.007	0.993	0.000
M54.9 Dorsalgia, unspecified	0.000	0.994	0.006
E10-E14 Diabetes mellitus	0.006	0.994	0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.000	0.994	0.006
E13 Other specified diabetes mellitus	0.006	0.994	0.000
E67.8 Other specified hyperalimentation	0.005	0.994	0.000
E67.3 Hypervitaminosis D	0.005	0.994	0.000
E67.2 Megavitamin-B6 syndrome	0.005	0.994	0.000
E67.1 Hypercarotenaemia	0.005	0.994	0.000
E67.0 Hypervitaminosis A	0.005	0.994	0.000
M54.2 Cervicalgia	0.000	0.995	0.005
E13.9 Without complications	0.005	0.995	0.000
H25.1 Senile nuclear cataract	0.000	0.995	0.005
M54.96 Dorsalgia, unspecified (Lumbar region)	0.000	0.995	0.005
R72 Abnormality of white blood cells, not elsewhere classified	0.005	0.995	0.000
M54.36 Sciatica (Lumbar region)	0.000	0.995	0.005
M54.97 Dorsalgia, unspecified (Lumbosacral region)	0.000	0.995	0.005
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)	0.000	0.995	0.004
E12 Malnutrition-related diabetes mellitus	0.004	0.995	0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)	0.000	0.995	0.004
M54.90 Dorsalgia, unspecified (Multiple sites in spine)	0.000	0.996	0.004
M54.64 Pain in thoracic spine (Thoracic region)	0.000	0.996	0.004
E13.8 With unspecified complications	0.004	0.996	0.000
E13.7 With multiple complications	0.004	0.996	0.000
E13.6 With other specified complications	0.004	0.996	0.000
E13.5 With peripheral circulatory complications	0.004	0.996	0.000
E13.4 With neurological complications	0.004	0.996	0.000
E13.3 With ophthalmic complications	0.004	0.996	0.000
E13.2 With renal complications	0.004	0.996	0.000
E13.1 With ketoacidosis	0.004	0.996	0.000
E13.0 With coma	0.004	0.996	0.000
M54.6 Pain in thoracic spine	0.000	0.996	0.004
M54 Dorsalgia	0.000	0.996	0.004
M54.23 Cervicalgia (Cervicothoracic region)	0.000	0.996	0.004
M54.27 Cervicalgia-Lumbosacral	0.000	0.996	0.004
M54.26 Cervicalgia-Lumbar	0.000	0.996	0.004
M54.25 Cervicalgia-Thoracolumbar	0.000	0.996	0.004
M54.24 Cervicalgia-Thoracic	0.000	0.996	0.004
M54.21 Cervicalgia (Occipito-atlanto-axial region)	0.000	0.996	0.004
M54.20 Cervicalgia-Mult site	0.000	0.996	0.004
M54.93 Dorsalgia, unspecified (Cervicothoracic region)	0.000	0.996	0.004
M54.92 Dorsalgia, unspecified (Cervical region)	0.000	0.996	0.004
M54.28 Cervicalgia-Sacral/sacrococ	0.000	0.996	0.004
S52.60 Fracture of lower end of both ulna and radius (closed)	0.004	0.996	0.000
J39 Other diseases of upper respiratory tract	0.004	0.996	0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)	0.000	0.996	0.004
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.000	0.996	0.004
M54.3 Sciatica	0.000	0.996	0.004
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.000	0.996	0.004
J39.0 Retropharyngeal and parapharyngeal abscess	0.004	0.996	0.000
E12.9 Without complications	0.003	0.996	0.000
E12.8 With unspecified complications	0.003	0.996	0.000
E12.7 With multiple complications	0.003	0.996	0.000
E12.6 With other specified complications	0.003	0.996	0.000
E12.5 With peripheral circulatory complications	0.003	0.996	0.000
E12.4 With neurological complications	0.003	0.996	0.000
E12.3 With ophthalmic complications	0.003	0.996	0.000
E12.2 With renal complications	0.003	0.996	0.000
E12.1 With ketoacidosis	0.003	0.996	0.000
E12.0 With coma	0.003	0.996	0.000
K91.4 Colostomy and enterostomy malfunction	0.004	0.996	0.000
E10.8 With unspecified complications	0.003	0.997	0.000
F33 Recurrent depressive disorder	0.000	0.997	0.003
H00.0 Hordeolum and other deep inflammation of eyelid	0.003	0.997	0.000
E10 Insulin-dependent diabetes mellitus	0.003	0.997	0.000
M54.69 Pain in thoracic spine-Site unspe	0.000	0.997	0.003
M54.68 Pain in thoracic spine-Sacral/sacrococ	0.000	0.997	0.003
M54.67 Pain in thoracic spine-Lumbosacral	0.000	0.997	0.003
M54.66 Pain in thoracic spine-Lumbar	0.000	0.997	0.003
M54.65 Pain in thoracic spine (Thoracolumbar region)	0.000	0.997	0.003
M54.63 Pain in thoracic spine (Cervicothoracic region)	0.000	0.997	0.003
M54.62 Pain in thoracic spine-Cervical	0.000	0.997	0.003
M54.61 Pain in thoracic spine-Occipit-atl-axl	0.000	0.997	0.003
M54.60 Pain in thoracic spine (Multiple sites in spine)	0.000	0.997	0.003
M54.0 Panniculitis affecting regions of neck and back	0.000	0.997	0.003
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract	0.000	0.997	0.003
E10.0 With coma	0.003	0.997	0.000
F33.9 Recurrent depressive disorder, unspecified	0.000	0.997	0.003
M54.29 Cervicalgia-Site unspe	0.000	0.997	0.003
M54.17 Radiculopathy (Lumbosacral region)	0.000	0.997	0.003
M54.94 Dorsalgia, unspecified (Thoracic region)	0.000	0.997	0.003
M54.1 Radiculopathy	0.000	0.997	0.003
M54.18 Radiculopathy (Sacral and sacrococcygeal region)	0.000	0.997	0.003
S52.80 Fracture of other parts of forearm (closed)	0.003	0.997	0.000
M90.78 Fracture of bone in neoplastic disease (Other)	0.000	0.997	0.003
H54.4 Blindness, one eye	0.000	0.997	0.003
F33.0 Recurrent depressive disorder, current episode mild	0.000	0.997	0.003
J39.3 Upper respiratory tract hypersensitivity reaction, site unspecified	0.003	0.997	0.000
J39.1 Other abscess of pharynx	0.003	0.997	0.000
M22.2 Patellofemoral disorders	0.000	0.997	0.003
E11.5 With peripheral circulatory complications	0.000	0.997	0.003
M54.8 Other dorsalgia	0.000	0.997	0.003
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.000	0.997	0.003
J39.9 Disease of upper respiratory tract, unspecified	0.003	0.997	0.000
E00-E07 Disorders of thyroid gland	0.003	0.997	0.000
M54.38 Sciatica (Sacral and sacrococcygeal region)	0.000	0.997	0.003
E10.7 With multiple complications	0.003	0.997	0.000
E10.2 With renal complications	0.003	0.997	0.000
M54.35 Sciatica (Thoracolumbar region)	0.000	0.997	0.003
M54.34 Sciatica-Thoracic	0.000	0.997	0.003
M54.33 Sciatica-Cervicothoracic	0.000	0.997	0.003
M54.32 Sciatica-Cervical	0.000	0.997	0.003
M54.31 Sciatica-Occipit-atl-axl	0.000	0.997	0.003
S52.6 Fracture of lower end of both ulna and radius	0.003	0.997	0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.000	0.997	0.003
M54.30 Sciatica (Multiple sites in spine)	0.000	0.997	0.003
K91.3 Postoperative intestinal obstruction	0.003	0.997	0.000
F33.8 Other recurrent depressive disorders	0.000	0.997	0.003
F33.4 Recurrent depressive disorder, currently in remission	0.000	0.997	0.003
Y40.9 Systemic antibiotic, unspecified	0.003	0.997	0.000
M54.09 Panniculitis affecting regions of neck and back (Site unspecified)	0.000	0.997	0.002
M54.08 Panniculitis affecting regions of neck and back (Sacral and sacrococcygeal region)	0.000	0.997	0.002
M54.07 Panniculitis affecting regions of neck and back (Lumbosacral region)	0.000	0.997	0.002
M54.06 Panniculitis affecting regions of neck and back (Lumbar region)	0.000	0.997	0.002
M54.05 Panniculitis affecting regions of neck and back (Thoracolumbar region)	0.000	0.997	0.002
M54.04 Panniculitis affecting regions of neck and back (Thoracic region)	0.000	0.997	0.002
M54.03 Panniculitis affecting regions of neck and back (Cervicothoracic region)	0.000	0.997	0.002
M54.02 Panniculitis affecting regions of neck and back (Cervical region)	0.000	0.997	0.002
M54.01 Panniculitis affecting regions of neck and back (Occipito-atlanto-axial region)	0.000	0.997	0.002
M54.00 Panniculitis affecting regions of neck and back (Multiple sites in spine)	0.000	0.997	0.002
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.000	0.997	0.003
M54.15 Radiculopathy (Thoracolumbar region)	0.000	0.997	0.002
M54.14 Radiculopathy (Thoracic region)	0.000	0.997	0.002
M54.13 Radiculopathy (Cervicothoracic region)	0.000	0.997	0.002
M54.11 Radiculopathy (Occipito-atlanto-axial region)	0.000	0.997	0.002
M54.10 Radiculopathy (Multiple sites in spine)	0.000	0.997	0.002
T84.2 Mechanical complication of internal fixation device of other bones	0.003	0.997	0.000
E10.5 With peripheral circulatory complications	0.002	0.997	0.000
S52.8 Fracture of other parts of forearm	0.003	0.997	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.003	0.997	0.000
K91.5 Postcholecystectomy syndrome	0.002	0.997	0.000
R71 Abnormality of red blood cells	0.002	0.997	0.000
M54.19 Radiculopathy (Site unspecified)	0.000	0.998	0.002
M54.88 Other dorsalgia (Sacral and sacrococcygeal region)	0.000	0.998	0.002
M54.87 Other dorsalgia (Lumbosacral region)	0.000	0.998	0.002
M54.85 Other dorsalgia (Thoracolumbar region)	0.000	0.998	0.002
M54.84 Other dorsalgia (Thoracic region)	0.000	0.998	0.002
M54.83 Other dorsalgia (Cervicothoracic region)	0.000	0.998	0.002
M54.82 Other dorsalgia (Cervical region)	0.000	0.998	0.002
M54.81 Other dorsalgia (Occipito-atlanto-axial region)	0.000	0.998	0.002
M54.80 Other dorsalgia (Multiple sites in spine)	0.000	0.998	0.002
E10.6 With other specified complications	0.002	0.998	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.002	0.998	0.000
E00 Congenital iodine-deficiency syndrome	0.002	0.998	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.002	0.998	0.000
M54.86 Other dorsalgia (Lumbar region)	0.000	0.998	0.002
S52.61 Fracture of lower end of both ulna and radius (open)	0.002	0.998	0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.002	0.998	0.000
F33.1 Recurrent depressive disorder, current episode moderate	0.000	0.998	0.002
T83.1 Mechanical complication of other urinary devices and implants	0.000	0.998	0.002
E05.8 Other thyrotoxicosis	0.002	0.998	0.000
H54.0 Blindness, both eyes	0.000	0.998	0.002
R25.2 Cramp and spasm	0.002	0.998	0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.002	0.998	0.000
T78.2 Anaphylactic shock, unspecified	0.002	0.998	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.002	0.998	0.000
S62.50 Fracture of thumb (closed)	0.002	0.998	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.002	0.998	0.000
T83.2 Mechanical complication of graft of urinary organ	0.000	0.998	0.002
S52.81 Fracture of other parts of forearm (open)	0.002	0.998	0.000
S52.0 Fracture of upper end of ulna	0.002	0.998	0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.000	0.998	0.002
T83.3 Mechanical complication of intra-uterine contraceptive device	0.000	0.998	0.002
M54.89 Other dorsalgia (Site unspecified)	0.000	0.998	0.002
E05.5 Thyroid crisis or storm	0.002	0.998	0.000
E05.4 Thyrotoxicosis factitia	0.002	0.998	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.002	0.998	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.002	0.998	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.002	0.998	0.000
Z98 Other postsurgical states	0.002	0.998	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.000	0.998	0.002
J98.4 Other disorders of lung	0.000	0.998	0.002
J61 Pneumoconiosis due to asbestos and other mineral fibres	0.002	0.998	0.000
S52 Fracture of forearm	0.002	0.998	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.002	0.998	0.000
M54.37 Sciatica (Lumbosacral region)	0.000	0.998	0.002
S52.00 Fracture of upper end of ulna (closed)	0.002	0.998	0.000
H44.2 Degenerative myopia	0.000	0.998	0.002
I46.9 Cardiac arrest, unspecified	0.000	0.998	0.002
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.002	0.998	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.002	0.998	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.002	0.998	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.002	0.998	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.002	0.998	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.002	0.998	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.002	0.998	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.002	0.998	0.000
M54.4 Lumbago with sciatica	0.000	0.998	0.002
R73.9 Hyperglycaemia, unspecified	0.002	0.998	0.000
X68.9 Unspecified place	0.000	0.998	0.002
Z98.8 Other specified postsurgical states	0.002	0.998	0.000
E05.9 Thyrotoxicosis, unspecified	0.002	0.998	0.000
H34.8 Other retinal vascular occlusions	0.000	0.998	0.002
R77 Other abnormalities of plasma proteins	0.002	0.998	0.000
H53.0 Amblyopia ex anopsia	0.000	0.998	0.002
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.002	0.998	0.000
S52.3 Fracture of shaft of radius	0.002	0.998	0.000
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)	0.002	0.998	0.000
L29.9 Pruritus, unspecified	0.002	0.998	0.000
S52.7 Multiple fractures of forearm	0.002	0.998	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.002	0.998	0.000
M54.12 Radiculopathy (Cervical region)	0.000	0.998	0.002
R76.0 Raised antibody titer	0.002	0.998	0.000
S52.01 Fracture of upper end of ulna (open)	0.002	0.998	0.000
E10.4 With neurological complications	0.002	0.998	0.000
K91.1 Postgastric surgery syndromes	0.002	0.998	0.000
R76 Other abnormal immunological findings in serum	0.002	0.998	0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]	0.002	0.998	0.000
H72.0 Central perforation of tympanic membrane	0.000	0.998	0.002
X78.0 Home	0.000	0.998	0.002
R73 Elevated blood glucose level	0.002	0.998	0.000
S52.30 Fracture of shaft of radius (closed)	0.002	0.998	0.000
G56.2 Lesion of ulnar nerve	0.000	0.998	0.002
K91.2 Postsurgical malabsorption, not elsewhere classified	0.002	0.998	0.000
R77.1 Abnormality of globulin	0.002	0.998	0.000
S52.70 Multiple fractures of forearm (closed)	0.002	0.998	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.002	0.998	0.000
R79.0 Abnormal level of blood mineral	0.002	0.998	0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.000	0.998	0.002
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.002	0.998	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.002	0.998	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.002	0.998	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.002	0.998	0.000
D22.7 Melanocytic naevi of lower limb, including hip	0.002	0.998	0.000
M90.7 Fracture of bone in neoplastic disease	0.000	0.998	0.002
S52.9 Fracture of forearm, part unspecified	0.002	0.998	0.000
S52.4 Fracture of shafts of both ulna and radius	0.002	0.998	0.000
K91.0 Vomiting following gastro-intestinal surgery	0.002	0.998	0.000
X62.9 Unspecified place	0.000	0.998	0.002
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.002	0.998	0.000
C83.1 Small cleaved cell (diffuse)	0.000	0.998	0.002
X68 Intentional self-poisoning by and exposure to pesticides	0.000	0.998	0.002
M54.48 Lumbago with sciatica (Sacral and sacrococcygeal region)	0.000	0.998	0.001
M54.45 Lumbago with sciatica (Thoracolumbar region)	0.000	0.998	0.001
M54.44 Lumbago with sciatica-Thoracic	0.000	0.998	0.001
M54.43 Lumbago with sciatica-Cervicothoracic	0.000	0.998	0.001
M54.42 Lumbago with sciatica-Cervical	0.000	0.998	0.001
M54.41 Lumbago with sciatica-Occipit-atl-axl	0.000	0.998	0.001
M54.40 Lumbago with sciatica (Multiple sites in spine)	0.000	0.998	0.001
R78 Findings of drugs and other substances, not normally found in blood	0.002	0.998	0.000
M24.16 Other articular cartilage disorders (Lower leg)	0.000	0.998	0.002
S22.20 Fracture of sternum (closed)	0.000	0.998	0.002
J92.9 Pleural plaque without asbestos	0.000	0.998	0.002
R77.2 Abnormality of alphafetoprotein	0.002	0.998	0.000
R77.0 Abnormality of albumin	0.002	0.998	0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity	0.002	0.998	0.000
F31.6 Bipolar affective disorder, current episode mixed	0.000	0.998	0.002
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.000	0.998	0.002
R76.9 Abnormal immunological finding in serum, unspecified	0.002	0.998	0.000
R77.8 Other specified abnormalities of plasma proteins	0.002	0.998	0.000
S52.31 Fracture of shaft of radius (open)	0.001	0.998	0.000
S52.71 Multiple fractures of forearm (open)	0.001	0.998	0.000
E10.3 With ophthalmic complications	0.002	0.998	0.000
G90.2 Horner's syndrome	0.002	0.998	0.000
T78.0 Anaphylactic shock due to adverse food reaction	0.002	0.998	0.000
X78 Intentional self-harm by sharp object	0.000	0.998	0.002
E10.1 With ketoacidosis	0.002	0.998	0.000
M20.5 Other deformities of toe(s) (acquired)	0.002	0.998	0.000
E14 Unspecified diabetes mellitus	0.002	0.998	0.000
H54 Blindness and low vision	0.000	0.998	0.002
H44.0 Purulent endophthalmitis	0.000	0.998	0.002
K91.9 Postprocedural disorder of digestive system, unspecified	0.001	0.998	0.000
M85.65 Other cyst of bone (Pelvic region and thigh)	0.002	0.998	0.000
R76.2 False-positive serological test for syphilis	0.001	0.998	0.000
R76.1 Abnormal reaction to tuberculin test	0.001	0.998	0.000
R77.9 Abnormality of plasma protein, unspecified	0.001	0.998	0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified	0.000	0.998	0.002
J39.8 Other specified diseases of upper respiratory tract	0.001	0.998	0.000
T18.1 Foreign body in oesophagus	0.002	0.998	0.000
X63.0 Home	0.000	0.998	0.002
M90.72 Fracture of bone in neoplastic disease (Upper arm)	0.000	0.998	0.001
E14.5 With peripheral circulatory complications	0.001	0.998	0.000
E14.2 Withrenal complications	0.001	0.998	0.000
G90.9 Disorder of autonomic nervous system, unspecified	0.002	0.998	0.000
S52.2 Fracture of shaft of ulna	0.001	0.998	0.000
M81.90 Osteoporosis, unspecified (Multiple sites)	0.000	0.998	0.002
S02.40 Fracture of malar and maxillary bones (closed)	0.002	0.998	0.000
X41.9 Unspecified place	0.000	0.998	0.002
E06 Thyroiditis	0.001	0.998	0.000
R79 Other abnormal findings of blood chemistry	0.002	0.998	0.000
S52.41 Fracture of shafts of both ulna and radius (open)	0.001	0.998	0.000
M90.79 Fracture of bone in neoplastic disease (Site unspecified)	0.000	0.998	0.001
M90.77 Fracture of bone in neoplastic disease (Ankle and foot)	0.000	0.998	0.001
M90.76 Fracture of bone in neoplastic disease (Lower leg)	0.000	0.998	0.001
M90.74 Fracture of bone in neoplastic disease (Hand)	0.000	0.998	0.001
M90.73 Fracture of bone in neoplastic disease (Forearm)	0.000	0.998	0.001
M90.71 Fracture of bone in neoplastic disease (Shoulder region)	0.000	0.998	0.001
M90.70 Fracture of bone in neoplastic disease (Multiple sites)	0.000	0.998	0.001
S52.40 Fracture of shafts of both ulna and radius (closed)	0.001	0.998	0.000
S52.91 Fracture of forearm, part unspecified (open)	0.001	0.998	0.000
S52.90 Fracture of forearm, part unspecified (closed)	0.001	0.998	0.000
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system	0.000	0.998	0.001
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.001	0.998	0.000
K55.2 Angiodysplasia of colon	0.002	0.998	0.000
T78.4 Allergy, unspecified	0.002	0.998	0.000
E87.0 Hyperosmolality and hypernatraemia	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations