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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs9295768
log Bayes Factor = 115.003
Chromosome 6   position 28,209,102  (GRCh37) Explore rs9295768 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
1.000 0.000 0.000
E83.1 Disorders of iron metabolism
0.000 0.000 1.000
K90.0 Coeliac disease
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
R31 Unspecified haematuria
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
K90 Intestinal malabsorption
1.000 0.000 0.000
M35.0 Sicca syndrome [Sjogren]
1.000 0.000 0.000
E10.3 With ophthalmic complications
0.999 0.001 0.000
M20-M25 Other joint disorders
0.999 0.001 0.000
M35 Other systemic involvement of connective tissue
0.999 0.001 0.000
E20-E35 Disorders of other endocrine glands
0.999 0.001 0.000
E27 Other disorders of adrenal gland
0.998 0.002 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.998 0.002 0.000
E27.1 Primary adrenocortical insufficiency
0.998 0.002 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.996 0.004 0.000
N40 Hyperplasia of prostate
0.000 0.004 0.996
M05-M14 Inflammatory polyarthropathies
0.995 0.005 0.000
E14 Unspecified diabetes mellitus
0.993 0.007 0.000
E16 Other disorders of pancreatic internal secretion
0.993 0.007 0.000
K75.4 Autoimmune hepatitis
0.992 0.008 0.000
K75 Other inflammatory liver diseases
0.992 0.008 0.000
E16.2 Hypoglycaemia, unspecified
0.990 0.010 0.000
E10.1 With ketoacidosis
0.990 0.010 0.000
K70-K77 Diseases of liver
0.989 0.011 0.000
K90.9 Intestinal malabsorption, unspecified
0.988 0.012 0.000
M07 Psoriatic and enteropathic arthropathies
0.987 0.013 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.986 0.014 0.000
# Top node
0.986 0.014 0.000
K90-K93 Other diseases of the digestive system
0.985 0.015 0.000
Chapter XI Diseases of the digestive system
0.984 0.015 0.001
E03 Other hypothyroidism
0.984 0.016 0.000
M07.3 Other psoriatic arthropathies
0.981 0.019 0.000
D50-D53 Nutritional anaemias
0.978 0.022 0.000
E03.9 Hypothyroidism, unspecified
0.975 0.025 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.975 0.025 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.974 0.026 0.000
D80-D89 Certain disorders involving the immune mechanism
0.972 0.028 0.000
E14.9 Without complications
0.971 0.029 0.000
D50 Iron deficiency anaemia
0.967 0.033 0.000
M31 Other necrotising vasculopathies
0.965 0.035 0.000
M34 Systemic sclerosis
0.961 0.039 0.000
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene
0.000 0.062 0.938
D50.8 Other iron deficiency anaemias
0.937 0.063 0.000
M60-M63 Disorders of muscles
0.936 0.064 0.000
K75.9 Inflammatory liver disease, unspecified
0.933 0.067 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.928 0.072 0.000
K72 Hepatic failure, not elsewhere classified
0.924 0.076 0.000
D50.9 Iron deficiency anaemia, unspecified
0.923 0.077 0.000
D86 Sarcoidosis
0.917 0.083 0.000
E10.2 With renal complications
0.913 0.087 0.000
K40 Inguinal hernia
0.000 0.088 0.912
M31.6 Other giant cell arteritis
0.910 0.090 0.000
M22 Disorders of patella
0.909 0.091 0.000
M15-M19 Arthrosis
0.907 0.093 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.901 0.099 0.000
M62 Other disorders of muscle
0.899 0.101 0.000
D55-D59 Haemolytic anaemias
0.899 0.101 0.000
K75.8 Other specified inflammatory liver diseases
0.897 0.103 0.000
M10 Gout
0.890 0.110 0.000
E14.3 With ophthalmic complications
0.886 0.114 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.886 0.114 0.000
M11 Other crystal arthropathies
0.884 0.116 0.000
M34.1 CR(E)ST syndrome
0.872 0.128 0.000
K73 Chronic hepatitis, not elsewhere classified
0.870 0.130 0.000
M17 Gonarthrosis [arthrosis of knee]
0.869 0.131 0.000
E10.5 With peripheral circulatory complications
0.863 0.137 0.000
M20 Acquired deformities of fingers and toes
0.009 0.137 0.854
E24 Cushing's syndrome
0.863 0.137 0.000
D86.9 Sarcoidosis, unspecified
0.860 0.140 0.000
E50-E64 Other nutritional deficiencies
0.859 0.141 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.857 0.143 0.000
E20 Hypoparathyroidism
0.855 0.145 0.000
M20.5 Other deformities of toe(s) (acquired)
0.000 0.145 0.855
E10.0 With coma
0.853 0.147 0.000
M20.1 Hallux valgus (acquired)
0.000 0.147 0.853
N40-N51 Diseases of male genital organs
0.000 0.151 0.849
M17.9 Gonarthrosis, unspecified
0.846 0.154 0.000
K40-K46 Hernia
0.009 0.154 0.837
Q50-Q56 Congenital malformations of genital organs
0.844 0.156 0.000
N42 Other disorders of prostate
0.000 0.162 0.838
M10.0 Idiopathic gout
0.838 0.162 0.000
K40.2 Bilateral inguinal hernia, without obstruction or gangrene
0.000 0.163 0.837
K44 Diaphragmatic hernia
0.004 0.170 0.826
M20.4 Other hammer toe(s) (acquired)
0.000 0.171 0.829
K72.0 Acute and subacute hepatic failure
0.827 0.173 0.000
M22.3 Other derangements of patella
0.825 0.175 0.000
M32 Systemic lupus erythematosus
0.823 0.177 0.000
K44.9 Diaphragmatic hernia without obstruction or gangrene
0.000 0.178 0.822
E16.0 Drug-induced hypoglycaemia without coma
0.821 0.179 0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.818 0.182 0.000
M91-M94 Chondropathies
0.818 0.182 0.000
D51 Vitamin B12 deficiency anaemia
0.818 0.182 0.000
M22.8 Other disorders of patella
0.816 0.184 0.000
M12 Other specific arthropathies
0.814 0.186 0.000
M34.8 Other forms of systemic sclerosis
0.814 0.186 0.000
M15 Polyarthrosis
0.812 0.188 0.000
M17.0 Primary gonarthrosis, bilateral
0.811 0.189 0.000
E11 Non-insulin-dependent diabetes mellitus
0.810 0.190 0.000
M34.9 Systemic sclerosis, unspecified
0.809 0.191 0.000
M62.8 Other specified disorders of muscle
0.809 0.191 0.000
E10.7 With multiple complications
0.807 0.193 0.000
E23 Hypofunction and other disorders of pituitary gland
0.802 0.198 0.000
M11.2 Other chondrocalcinosis
0.801 0.199 0.000
M31.0 Hypersensitivity angiitis
0.799 0.201 0.000
E14.1 With ketoacidosis
0.798 0.202 0.000
E31 Polyglandular dysfunction
0.797 0.203 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.791 0.208 0.000
M10.07 Idiopathic gout (Ankle and foot)
0.790 0.210 0.000
D84 Other immunodeficiencies
0.789 0.211 0.000
D58 Other hereditary haemolytic anaemias
0.788 0.212 0.000
D83 Common variable immunodeficiency
0.787 0.213 0.000
N48 Other disorders of penis
0.000 0.220 0.780
M07.30 Other psoriatic arthropathies (Multiple sites)
0.779 0.221 0.000
M65-M68 Disorders of synovium and tendon
0.775 0.225 0.000
E53 Deficiency of other B group vitamins
0.772 0.228 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.772 0.228 0.000
N48.4 Impotence of organic origin
0.000 0.229 0.771
M62.6 Muscle strain
0.769 0.231 0.000
E11.3 With ophthalmic complications
0.766 0.234 0.000
E27.2 Addisonian crisis
0.763 0.237 0.000
E11.5 With peripheral circulatory complications
0.761 0.239 0.000
D59 Acquired haemolytic anaemia
0.761 0.239 0.000
N42.8 Other specified disorders of prostate
0.000 0.241 0.759
D89.2 Hypergammaglobulinaemia, unspecified
0.758 0.242 0.000
D60-D64 Aplastic and other anaemias
0.757 0.243 0.000
M35.3 Polymyalgia rheumatica
0.757 0.243 0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.756 0.244 0.000
M18 Arthrosis of first carpometacarpal joint
0.754 0.246 0.000
E20.9 Hypoparathyroidism, unspecified
0.752 0.248 0.000
E25 Adrenogenital disorders
0.752 0.248 0.000
K72.9 Hepatic failure, unspecified
0.751 0.249 0.000
K73.2 Chronic active hepatitis, not elsewhere classified
0.746 0.254 0.000
M93 Other osteochondropathies
0.746 0.254 0.000
N42.1 Congestion and haemorrhage of prostate
0.000 0.257 0.743
E14.6 With other specified complications
0.742 0.258 0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified
0.740 0.259 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.739 0.261 0.000
E14.8 With unspecified complications
0.736 0.263 0.000
K90.8 Other intestinal malabsorption
0.736 0.264 0.000
E24.2 Drug-induced Cushing's syndrome
0.735 0.265 0.000
D52 Folate deficiency anaemia
0.734 0.266 0.000
M67 Other disorders of synovium and tendon
0.734 0.266 0.000
E10.6 With other specified complications
0.733 0.267 0.000
K72.1 Chronic hepatic failure
0.732 0.268 0.000
D64 Other anaemias
0.729 0.271 0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments
0.729 0.271 0.000
E10.4 With neurological complications
0.727 0.273 0.000
M35.1 Other overlap syndromes
0.727 0.273 0.000
E14.5 With peripheral circulatory complications
0.726 0.274 0.000
D86.0 Sarcoidosis of lung
0.726 0.274 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.725 0.275 0.000
M62.86 Other specified disorders of muscle (Lower leg)
0.723 0.277 0.000
E14.2 Withrenal complications
0.723 0.277 0.000
M11.26 Other chondrocalcinosis (Lower leg)
0.721 0.279 0.000
D80 Immunodeficiency with predominantly antibody defects
0.718 0.282 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.717 0.283 0.000
K90.3 Pancreatic steatorrhoea
0.717 0.283 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.717 0.283 0.000
K90.1 Tropical sprue
0.717 0.283 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.716 0.283 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.716 0.284 0.000
M35.8 Other specified systemic involvement of connective tissue
0.716 0.284 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.716 0.284 0.000
M35.5 Multifocal fibrosclerosis
0.716 0.284 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.716 0.284 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.716 0.284 0.000
E32 Diseases of thymus
0.716 0.284 0.000
E30 Disorders of puberty, not elsewhere classified
0.716 0.284 0.000
E27.5 Adrenomedullary hyperfunction
0.716 0.284 0.000
E27.0 Other adrenocortical overactivity
0.716 0.284 0.000
K41 Femoral hernia
0.003 0.285 0.712
E23.2 Diabetes insipidus
0.715 0.285 0.000
E15 Nondiabetic hypoglycaemic coma
0.714 0.286 0.000
M14 Arthropathies in other diseases classified elsewhere
0.714 0.286 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.713 0.287 0.000
M08 Juvenile arthritis
0.713 0.287 0.000
D86.1 Sarcoidosis of lymph nodes
0.713 0.287 0.000
E24.0 Pituitary-dependent Cushing's disease
0.713 0.287 0.000
E14.7 With multiple complications
0.712 0.288 0.000
E14.0 With coma
0.712 0.288 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.712 0.288 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.712 0.288 0.000
E16.4 Abnormal secretion of gastrin
0.712 0.288 0.000
E16.3 Increased secretion of glucagon
0.712 0.288 0.000
K75.3 Granulomatous hepatitis, not elsewhere classified
0.711 0.288 0.000
K75.2 Nonspecific reactive hepatitis
0.711 0.288 0.000
K75.1 Phlebitis of portal vein
0.711 0.288 0.000
D64.9 Anaemia, unspecified
0.711 0.289 0.000
K77 Liver disorders in diseases classified elsewhere
0.709 0.291 0.000
K71 Toxic liver disease
0.709 0.291 0.000
N48.1 Balanoposthitis
0.000 0.291 0.709
M07.6 Other enteropathic arthropathies
0.707 0.292 0.000
M07.5 Arthropathy in ulcerative colitis
0.707 0.292 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.707 0.292 0.000
M07.2 Psoriatic spondylitis
0.707 0.292 0.000
M07.1 Arthritis mutilans
0.707 0.292 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.707 0.292 0.000
Q53 Undescended testicle
0.707 0.292 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.707 0.293 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.707 0.293 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.706 0.293 0.000
E16.1 Other hypoglycaemia
0.705 0.294 0.000
E03.5 Myxoedema coma
0.705 0.295 0.000
E03.4 Atrophy of thyroid (acquired)
0.705 0.295 0.000
E03.3 Postinfectious hypothyroidism
0.705 0.295 0.000
E03.1 Congenital hypothyroidism without goitre
0.705 0.295 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.705 0.295 0.000
M31.9 Necrotising vasculopathy, unspecified
0.705 0.295 0.000
E14.4 With neurological complications
0.704 0.296 0.000
M07.38 Other psoriatic arthropathies (Other)
0.703 0.296 0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.703 0.296 0.000
M07.34 Other psoriatic arthropathies (Hand)
0.703 0.296 0.000
M07.33 Other psoriatic arthropathies (Forearm)
0.703 0.296 0.000
M07.32 Other psoriatic arthropathies (Upper arm)
0.703 0.296 0.000
M07.31 Other psoriatic arthropathies (Shoulder region)
0.703 0.296 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.702 0.298 0.000
Q00-Q07 Congenital malformations of the nervous system
0.702 0.298 0.000
N41 Inflammatory diseases of prostate
0.000 0.299 0.701
M31.1 Thrombotic microangiopathy
0.700 0.300 0.000
D82 Immunodeficiency associated with other major defects
0.697 0.303 0.000
D81 Combined immunodeficiencies
0.697 0.303 0.000
M32.1 Systemic lupus erythematosus with organ or system involvement
0.696 0.304 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.002 0.306 0.692
E53.8 Deficiency of other specified B group vitamins
0.694 0.306 0.000
M15.8 Other polyarthrosis
0.694 0.306 0.000
M93.9 Osteochondropathy, unspecified
0.694 0.306 0.000
D50.1 Sideropenic dysphagia
0.693 0.307 0.000
M31.8 Other specified necrotising vasculopathies
0.692 0.308 0.000
M31.7 Microscopic polyangiitis
0.692 0.308 0.000
M31.4 Aortic arch syndrome [Takayasu]
0.692 0.308 0.000
M31.2 Lethal midline granuloma
0.692 0.308 0.000
N42.0 Calculus of prostate
0.000 0.309 0.691
N42.2 Atrophy of prostate
0.000 0.310 0.690
M34.2 Systemic sclerosis induced by drugs and chemicals
0.689 0.311 0.000
M34.0 Progressive systemic sclerosis
0.689 0.311 0.000
M86-M90 Other osteopathies
0.689 0.311 0.000
Q51 Congenital malformations of uterus and cervix
0.687 0.313 0.000
N42.9 Disorder of prostate, unspecified
0.000 0.313 0.687
M67.8 Other specified disorders of synovium and tendon
0.685 0.315 0.000
D53 Other nutritional anaemias
0.683 0.317 0.000
M33 Dermatopolymyositis
0.678 0.322 0.000
E61 Deficiency of other nutrient elements
0.678 0.322 0.000
M22.2 Patellofemoral disorders
0.678 0.322 0.000
K74 Fibrosis and cirrhosis of liver
0.676 0.324 0.000
M62.0 Diastasis of muscle
0.674 0.326 0.000
K40.0 Bilateral inguinal hernia, with obstruction, without gangrene
0.000 0.327 0.673
M63 Disorders of muscle in diseases classified elsewhere
0.671 0.329 0.000
M61 Calcification and ossification of muscle
0.671 0.329 0.000
M62.83 Other specified disorders of muscle (Forearm)
0.670 0.329 0.000
M62.82 Other specified disorders of muscle (Upper arm)
0.669 0.331 0.000
E10.8 With unspecified complications
0.668 0.332 0.000
K73.8 Other chronic hepatitis, not elsewhere classified
0.666 0.334 0.000
M00-M03 Infectious arthropathies
0.665 0.335 0.000
K73.9 Chronic hepatitis, unspecified
0.662 0.338 0.000
M18.1 Other primary arthrosis of first carpometacarpal joint
0.662 0.338 0.000
D58.9 Hereditary haemolytic anaemia, unspecified
0.661 0.339 0.000
M62.81 Other specified disorders of muscle (Shoulder region)
0.659 0.341 0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.658 0.342 0.000
D84.9 Immunodeficiency, unspecified
0.657 0.342 0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral
0.657 0.343 0.000
D86.3 Sarcoidosis of skin
0.656 0.344 0.000
E05.8 Other thyrotoxicosis
0.655 0.344 0.000
D83.9 Common variable immunodeficiency, unspecified
0.654 0.346 0.000
K40.4 Unilateral or unspecified inguinal hernia, with gangrene
0.000 0.346 0.654
K40.1 Bilateral inguinal hernia, with gangrene
0.000 0.346 0.654
E29 Testicular dysfunction
0.653 0.347 0.000
E31.0 Autoimmune polyglandular failure
0.653 0.347 0.000
Q54 Hypospadias
0.652 0.348 0.000
K40.3 Unilateral or unspecified inguinal hernia, with obstruction, without gangrene
0.000 0.348 0.652
M22.1 Recurrent subluxation of patella
0.651 0.348 0.000
K70 Alcoholic liver disease
0.651 0.348 0.000
D59.9 Acquired haemolytic anaemia, unspecified
0.651 0.349 0.000
E40-E46 Malnutrition
0.650 0.350 0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified
0.650 0.350 0.000
D58.0 Hereditary spherocytosis
0.649 0.351 0.000
M86 Osteomyelitis
0.648 0.352 0.000
Q50.4 Embryonic cyst of Fallopian tube
0.646 0.354 0.000
M10.06 Idiopathic gout (Lower leg)
0.646 0.354 0.000
M12.2 Villonodular synovitis (pigmented)
0.646 0.354 0.000
M62.9 Disorder of muscle, unspecified
0.645 0.355 0.000
M62.4 Contracture of muscle
0.645 0.355 0.000
M62.3 Immobility syndrome (paraplegic)
0.645 0.355 0.000
M62.2 Ischaemic infarction of muscle
0.645 0.355 0.000
D57 Sickle-cell disorders
0.644 0.356 0.000
D55 Anaemia due to enzyme disorders
0.644 0.356 0.000
M62.65 Muscle strain (Pelvic region and thigh)
0.644 0.356 0.000
E07 Other disorders of thyroid
0.643 0.357 0.000
K46 Unspecified abdominal hernia
0.005 0.358 0.638
M15.1 Heberden's nodes (with arthropathy)
0.641 0.359 0.000
M22.9 Disorder of patella, unspecified
0.640 0.360 0.000
M35.7 Hypermobility syndrome
0.640 0.360 0.000
M11.9 Crystal arthropathy, unspecified
0.640 0.360 0.000
M10.4 Other secondary gout
0.638 0.362 0.000
M10.3 Gout due to impairment of renal function
0.638 0.362 0.000
M10.2 Drug-induced gout
0.638 0.362 0.000
M10.1 Lead-induced gout
0.638 0.362 0.000
M11.8 Other specified crystal arthropathies
0.636 0.363 0.000
M12.3 Palindromic rheumatism
0.636 0.364 0.000
M62.1 Other rupture of muscle (nontraumatic)
0.636 0.364 0.000
Q35-Q37 Cleft lip and cleft palate
0.635 0.365 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.635 0.365 0.000
D56 Thalassaemia
0.634 0.366 0.000
Q52 Other congenital malformations of female genitalia
0.634 0.366 0.000
M11.1 Familial chondrocalcinosis
0.634 0.366 0.000
M11.0 Hydroxyapatite deposition disease
0.634 0.366 0.000
M11.27 Other chondrocalcinosis (Ankle and foot)
0.633 0.367 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.632 0.368 0.000
M21 Other acquired deformities of limbs
0.632 0.368 0.000
Q40 Other congenital malformations of upper alimentary tract
0.629 0.371 0.000
E06 Thyroiditis
0.628 0.372 0.000
D89.9 Disorder involving the immune mechanism, unspecified
0.628 0.372 0.000
M13 Other arthritis
0.627 0.373 0.000
Q45 Other congenital malformations of digestive system
0.627 0.373 0.000
D89.1 Cryoglobulinaemia
0.626 0.374 0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.624 0.376 0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.624 0.376 0.000
M17.2 Posttraumatic gonarthrosis, bilateral
0.623 0.377 0.000
E22 Hyperfunction of pituitary gland
0.623 0.377 0.000
E51 Thiamine deficiency
0.622 0.378 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.000 0.378 0.622
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.621 0.378 0.000
M30 Polyarteritis nodosa and related conditions
0.621 0.378 0.000
M17.3 Other posttraumatic gonarthrosis
0.621 0.379 0.000
N48.2 Other inflammatory disorders of penis
0.000 0.380 0.620
M60 Myositis
0.619 0.381 0.000
E24.8 Other Cushing's syndrome
0.618 0.381 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.618 0.381 0.000
E24.3 Ectopic ACTH syndrome
0.618 0.381 0.000
E24.1 Nelson's syndrome
0.618 0.381 0.000
M15.2 Bouchard's nodes (with arthropathy)
0.617 0.383 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.616 0.384 0.000
E63 Other nutritional deficiencies
0.616 0.384 0.000
E56 Other vitamin deficiencies
0.616 0.384 0.000
E50 Vitamin A deficiency
0.616 0.384 0.000
E60 Dietary zinc deficiency
0.616 0.384 0.000
E59 Dietary selenium deficiency
0.616 0.384 0.000
E58 Dietary calcium deficiency
0.616 0.384 0.000
E54 Ascorbic acid deficiency
0.616 0.384 0.000
E52 Niacin deficiency [pellagra]
0.616 0.384 0.000
M06 Other rheumatoid arthritis
0.615 0.385 0.000
D89.3 Immune reconstitution syndrome
0.614 0.386 0.000
K70.0 Alcoholic fatty liver
0.614 0.386 0.000
D86.8 Sarcoidosis of other and combined sites
0.614 0.386 0.000
E20.8 Other hypoparathyroidism
0.613 0.387 0.000
E20.1 Pseudohypoparathyroidism
0.613 0.387 0.000
E20.0 Idiopathic hypoparathyroidism
0.613 0.387 0.000
M35.2 Behcet's disease
0.613 0.387 0.000
E27.9 Disorder of adrenal gland, unspecified
0.613 0.387 0.000
K41.3 Unilateral or unspecified femoral hernia, with obstruction, without gangrene
0.001 0.389 0.610
M10.09 Idiopathic gout (Site unspecified)
0.609 0.391 0.000
M20.0 Deformity of finger(s)
0.004 0.392 0.605
M62.66 Muscle strain (Lower leg)
0.606 0.394 0.000
Q56 Indeterminate sex and pseudohermaphroditism
0.605 0.395 0.000
Q55 Other congenital malformations of male genital organs
0.605 0.395 0.000
M17.4 Other secondary gonarthrosis, bilateral
0.605 0.395 0.000
N44 Torsion of testis
0.000 0.395 0.604
N41.0 Acute prostatitis
0.000 0.397 0.603
N42.3 Dysplasia of prostate
0.000 0.399 0.601
M10.08 Idiopathic gout (Other)
0.601 0.399 0.000
M10.05 Idiopathic gout (Pelvic region and thigh)
0.601 0.399 0.000
M10.04 Idiopathic gout (Hand)
0.601 0.399 0.000
M10.03 Idiopathic gout (Forearm)
0.601 0.399 0.000
M10.02 Idiopathic gout (Upper arm)
0.601 0.399 0.000
M10.01 Idiopathic gout (Shoulder region)
0.601 0.399 0.000
M10.00 Idiopathic gout (Multiple sites)
0.601 0.399 0.000
M15.9 Polyarthrosis, unspecified
0.600 0.400 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.599 0.401 0.000
E53.9 Vitamin B deficiency, unspecified
0.597 0.403 0.000
E03.8 Other specified hypothyroidism
0.596 0.404 0.000
M62.51 Muscle wasting and atrophy, not elsewhere classified (Shoulder region)
0.595 0.405 0.000
K44.1 Diaphragmatic hernia with gangrene
0.003 0.405 0.592
N46 Male infertility
0.000 0.408 0.592
D89.0 Polyclonal hypergammaglobulinaemia
0.591 0.409 0.000
M15.4 Erosive (osteo)arthrosis
0.590 0.410 0.000
M32.9 Systemic lupus erythematosus, unspecified
0.590 0.410 0.000
M32.8 Other forms of systemic lupus erythematosus
0.590 0.410 0.000
M32.0 Drug-induced systemic lupus erythematosus
0.590 0.410 0.000
E23.0 Hypopituitarism
0.589 0.411 0.000
D51.8 Other vitamin B12 deficiency anaemias
0.586 0.413 0.000
D51.3 Other dietary vitamin B12 deficiency anaemia
0.586 0.413 0.000
D51.2 Transcobalamin II deficiency
0.586 0.413 0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.586 0.413 0.000
M12.8 Other specific arthropathies, not elsewhere classified
0.583 0.416 0.000
M12.5 Traumatic arthropathy
0.583 0.416 0.000
M12.4 Intermittent hydrarthrosis
0.583 0.416 0.000
M12.1 Kaschin-Beck disease
0.583 0.416 0.000
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.583 0.416 0.000
M15.0 Primary generalised (osteo)arthrosis
0.582 0.418 0.000
E11.7 With multiple complications
0.581 0.419 0.000
M62.87 Other specified disorders of muscle (Ankle and foot)
0.580 0.420 0.000
M62.84 Other specified disorders of muscle (Hand)
0.580 0.420 0.000
Q39 Congenital malformations of oesophagus
0.578 0.422 0.000
E11.6 With other specified complications
0.578 0.422 0.000
M67.4 Ganglion
0.578 0.422 0.000
Q68 Other congenital musculoskeletal deformities
0.577 0.423 0.000
M62.54 Muscle wasting and atrophy, not elsewhere classified (Hand)
0.576 0.424 0.000
D64.3 Other sideroblastic anaemias
0.576 0.424 0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.576 0.424 0.000
M15.3 Secondary multiple arthrosis
0.575 0.424 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.575 0.425 0.000
E23.1 Drug-induced hypopituitarism
0.575 0.425 0.000
M11.29 Other chondrocalcinosis (Site unspecified)
0.574 0.426 0.000
M11.28 Other chondrocalcinosis (Other)
0.574 0.426 0.000
M11.25 Other chondrocalcinosis (Pelvic region and thigh)
0.574 0.426 0.000
M11.24 Other chondrocalcinosis (Hand)
0.574 0.426 0.000
M11.23 Other chondrocalcinosis (Forearm)
0.574 0.426 0.000
M11.22 Other chondrocalcinosis (Upper arm)
0.574 0.426 0.000
M11.21 Other chondrocalcinosis (Shoulder region)
0.574 0.426 0.000
M11.20 Other chondrocalcinosis (Multiple sites)
0.574 0.426 0.000
Q53.1 Undescended testicle, unilateral
0.574 0.426 0.000
M22.0 Recurrent dislocation of patella
0.572 0.428 0.000
E31.9 Polyglandular dysfunction, unspecified
0.571 0.428 0.000
E31.8 Other polyglandular dysfunction
0.571 0.428 0.000
E31.1 Polyglandular hyperfunction
0.571 0.428 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.571 0.428 0.000
Q43 Other congenital malformations of intestine
0.571 0.429 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.000 0.430 0.570
M67.2 Synovial hypertrophy, not elsewhere classified
0.568 0.432 0.000
M31.3 Wegener's granulomatosis
0.567 0.433 0.000
D59.1 Other autoimmune haemolytic anaemias
0.566 0.434 0.000
D84.8 Other specified immunodeficiencies
0.566 0.434 0.000
D84.1 Defects in the complement system
0.566 0.434 0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect
0.566 0.434 0.000
D58.8 Other specified hereditary haemolytic anaemias
0.565 0.435 0.000
D58.2 Other haemoglobinopathies
0.565 0.435 0.000
D58.1 Hereditary elliptocytosis
0.565 0.435 0.000
Q74 Other congenital malformations of limb(s)
0.565 0.435 0.000
D83.8 Other common variable immunodeficiencies
0.564 0.436 0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells
0.564 0.436 0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders
0.564 0.436 0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function
0.564 0.436 0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified
0.563 0.437 0.000
Q53.9 Undescended testicle, unspecified
0.561 0.439 0.000
E26 Hyperaldosteronism
0.561 0.439 0.000
D52.9 Folate deficiency anaemia, unspecified
0.559 0.441 0.000
E24.9 Cushing's syndrome, unspecified
0.559 0.441 0.000
Q07 Other congenital malformations of nervous system
0.558 0.442 0.000
M13.0 Polyarthritis, unspecified
0.558 0.442 0.000
Q04 Other congenital malformations of brain
0.558 0.442 0.000
E28 Ovarian dysfunction
0.557 0.443 0.000
M86.6 Other chronic osteomyelitis
0.557 0.443 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.556 0.444 0.000
E13 Other specified diabetes mellitus
0.555 0.445 0.000
Q54.1 Hypospadias, penile
0.554 0.446 0.000
E53.1 Pyridoxine deficiency
0.554 0.446 0.000
E53.0 Riboflavin deficiency
0.554 0.446 0.000
Q42 Congenital absence, atresia and stenosis of large intestine
0.553 0.446 0.000
Q41 Congenital absence, atresia and stenosis of small intestine
0.553 0.446 0.000
M25 Other joint disorders, not elsewhere classified
0.553 0.447 0.000
Q99 Other chromosome abnormalities, not elsewhere classified
0.553 0.447 0.000
M91 Juvenile osteochondrosis of hip and pelvis
0.551 0.449 0.000
M62.69 Muscle strain (Site unspecified)
0.551 0.449 0.000
M62.68 Muscle strain (Other)
0.551 0.449 0.000
M62.67 Muscle strain (Ankle and foot)
0.551 0.449 0.000
M62.64 Muscle strain (Hand)
0.551 0.449 0.000
M62.63 Muscle strain (Forearm)
0.551 0.449 0.000
M62.62 Muscle strain (Upper arm)
0.551 0.449 0.000
M62.61 Muscle strain (Shoulder region)
0.551 0.449 0.000
M62.60 Muscle strain (Multiple sites)
0.551 0.449 0.000
M67.0 Short Achilles tendon (acquired)
0.550 0.450 0.000
M62.80 Other specified disorders of muscle (Multiple sites)
0.549 0.450 0.000
M94 Other disorders of cartilage
0.547 0.453 0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.547 0.453 0.000
D59.8 Other acquired haemolytic anaemias
0.545 0.455 0.000
D59.6 Haemoglobinuria due to haemolysis from other external causes
0.545 0.455 0.000
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]
0.545 0.455 0.000
D59.4 Other nonautoimmune haemolytic anaemias
0.545 0.455 0.000
D59.3 Haemolytic-uraemic syndrome
0.545 0.455 0.000
D59.2 Drug-induced nonautoimmune haemolytic anaemia
0.545 0.455 0.000
D59.0 Drug-induced autoimmune haemolytic anaemia
0.545 0.455 0.000
Q51.8 Other congenital malformations of uterus and cervix
0.544 0.456 0.000
E11.0 With coma
0.543 0.457 0.000
M62.85 Other specified disorders of muscle (Pelvic region and thigh)
0.542 0.458 0.000
M18.5 Other secondary arthrosis of first carpometacarpal joint
0.541 0.459 0.000
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral
0.541 0.459 0.000
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint
0.541 0.459 0.000
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral
0.541 0.459 0.000
E25.9 Adrenogenital disorder, unspecified
0.539 0.460 0.000
E25.8 Other adrenogenital disorders
0.539 0.460 0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified
0.538 0.462 0.000
N48.5 Ulcer of penis
0.000 0.463 0.537
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene
0.001 0.464 0.536
M86.9 Osteomyelitis, unspecified
0.535 0.465 0.000
M93.8 Other specified osteochondropathies
0.535 0.465 0.000
M93.2 Osteochondritis dissecans
0.535 0.465 0.000
M93.1 Kienbock's disease of adults
0.535 0.465 0.000
M93.0 Slipped upper femoral epiphysis (nontraumatic)
0.535 0.465 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.534 0.466 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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