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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs9295967
log Bayes Factor = 46.4675
Chromosome 6   position 31,184,020  (GRCh37) Explore rs9295967 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.001 0.999
G35 Multiple sclerosis
0.000 0.002 0.998
M45.X9 Ankylosing spondylitis (Site unspecified)
0.997 0.003 0.000
E10-E14 Diabetes mellitus
0.000 0.003 0.997
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.006 0.994
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.007 0.993
E16 Other disorders of pancreatic internal secretion
0.000 0.008 0.992
E16.2 Hypoglycaemia, unspecified
0.000 0.008 0.992
E10.1 With ketoacidosis
0.000 0.015 0.985
E00-E07 Disorders of thyroid gland
0.000 0.033 0.967
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.035 0.965
M45 Ankylosing spondylitis
0.947 0.053 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.055 0.945
E05.9 Thyrotoxicosis, unspecified
0.000 0.109 0.891
E10.2 With renal complications
0.000 0.113 0.887
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.878 0.122 0.000
M45.X2 Ankylosing spondylitis (Cervical region)
0.875 0.125 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.863 0.137 0.000
M06.9 Rheumatoid arthritis, unspecified
0.859 0.141 0.000
E13 Other specified diabetes mellitus
0.000 0.145 0.855
E10.5 With peripheral circulatory complications
0.000 0.156 0.844
E10.9 Without complications
0.000 0.157 0.843
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.161 0.839
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.175 0.825
E06 Thyroiditis
0.000 0.193 0.807
E65-E68 Obesity and other hyperalimentation
0.000 0.205 0.795
E10.8 With unspecified complications
0.000 0.217 0.783
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.780 0.220 0.000
E14 Unspecified diabetes mellitus
0.000 0.225 0.775
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.774 0.226 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.768 0.232 0.000
E05.8 Other thyrotoxicosis
0.000 0.242 0.758
E10.0 With coma
0.000 0.246 0.754
E13.9 Without complications
0.000 0.246 0.754
E10.6 With other specified complications
0.000 0.248 0.752
E10.4 With neurological complications
0.000 0.258 0.742
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.263 0.737
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.729 0.271 0.000
E14.3 With ophthalmic complications
0.000 0.281 0.719
E10.7 With multiple complications
0.000 0.283 0.717
E40-E46 Malnutrition
0.000 0.284 0.716
E12 Malnutrition-related diabetes mellitus
0.000 0.285 0.715
E15 Nondiabetic hypoglycaemic coma
0.000 0.288 0.712
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.288 0.711
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.288 0.711
E16.4 Abnormal secretion of gastrin
0.000 0.288 0.711
E16.3 Increased secretion of glucagon
0.000 0.288 0.711
E06.9 Thyroiditis, unspecified
0.000 0.290 0.710
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.306 0.693
E00 Congenital iodine-deficiency syndrome
0.000 0.306 0.693
E05.5 Thyroid crisis or storm
0.000 0.308 0.692
E05.4 Thyrotoxicosis factitia
0.000 0.308 0.692
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.308 0.692
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.308 0.692
M06 Other rheumatoid arthritis
0.680 0.320 0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.679 0.321 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.679 0.321 0.000
M45.X6 Ankylosing spondylitis (Lumbar region)
0.679 0.321 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.679 0.321 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.679 0.321 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.679 0.321 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.679 0.321 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.673 0.327 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.667 0.333 0.000
E14.4 With neurological complications
0.000 0.367 0.633
E16.1 Other hypoglycaemia
0.000 0.368 0.632
E20-E35 Disorders of other endocrine glands
0.000 0.372 0.628
E66 Obesity
0.000 0.376 0.624
E13.8 With unspecified complications
0.000 0.387 0.613
E13.7 With multiple complications
0.000 0.387 0.613
E13.6 With other specified complications
0.000 0.387 0.613
E13.5 With peripheral circulatory complications
0.000 0.387 0.613
E13.4 With neurological complications
0.000 0.387 0.613
E13.3 With ophthalmic complications
0.000 0.387 0.613
E13.2 With renal complications
0.000 0.387 0.613
E13.1 With ketoacidosis
0.000 0.387 0.613
E13.0 With coma
0.000 0.387 0.613
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.611 0.389 0.000
E06.3 Autoimmune thyroiditis
0.000 0.391 0.609
E65 Localised adiposity
0.000 0.393 0.607
M06.98 Rheumatoid arthritis, unspecified (Other)
0.600 0.400 0.000
M06.3 Rheumatoid nodule
0.597 0.403 0.000
M06.0 Seronegative rheumatoid arthritis
0.592 0.408 0.000
K90 Intestinal malabsorption
0.000 0.417 0.583
E06.4 Drug-induced thyroiditis
0.000 0.421 0.579
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.421 0.579
E06.1 Subacute thyroiditis
0.000 0.421 0.579
E06.0 Acute thyroiditis
0.000 0.421 0.579
E66.8 Other obesity
0.000 0.427 0.573
E67 Other hyperalimentation
0.000 0.430 0.570
E68 Sequelae of hyperalimentation
0.000 0.430 0.570
E14.8 With unspecified complications
0.000 0.444 0.556
E14.7 With multiple complications
0.000 0.444 0.556
E14.2 Withrenal complications
0.000 0.444 0.556
E14.1 With ketoacidosis
0.000 0.444 0.556
E14.0 With coma
0.000 0.444 0.556
M06.34 Rheumatoid nodule (Hand)
0.550 0.450 0.000
E50-E64 Other nutritional deficiencies
0.000 0.461 0.539
E34 Other endocrine disorders
0.000 0.468 0.532
E14.5 With peripheral circulatory complications
0.000 0.477 0.523
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.520 0.480 0.000
E46 Unspecified protein-energy malnutrition
0.000 0.483 0.517
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.486 0.513
E45 Retarded development following protein-energy malnutrition
0.000 0.486 0.513
E43 Unspecified severe protein-energy malnutrition
0.000 0.486 0.513
E42 Marasmic kwashiorkor
0.000 0.486 0.513
E41 Nutritional marasmus
0.000 0.486 0.513
E40 Kwashiorkor
0.000 0.486 0.513
E26 Hyperaldosteronism
0.000 0.487 0.513
E12.9 Without complications
0.000 0.487 0.512
E12.8 With unspecified complications
0.000 0.487 0.512
E12.7 With multiple complications
0.000 0.487 0.512
E12.6 With other specified complications
0.000 0.487 0.512
E12.5 With peripheral circulatory complications
0.000 0.487 0.512
E12.4 With neurological complications
0.000 0.487 0.512
E12.3 With ophthalmic complications
0.000 0.487 0.512
E12.2 With renal complications
0.000 0.487 0.512
E12.1 With ketoacidosis
0.000 0.487 0.512
E12.0 With coma
0.000 0.487 0.512
E66.0 Obesity due to excess calories
0.000 0.489 0.511
E14.6 With other specified complications
0.000 0.493 0.506
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.496 0.504
E24 Cushing's syndrome
0.000 0.497 0.503
E06.5 Other chronic thyroiditis
0.000 0.502 0.498
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.503 0.497
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.503 0.497
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.503 0.497
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.503 0.497
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.503 0.497
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.503 0.497
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.503 0.497
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.503 0.497
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.509 0.491
M06.8 Other specified rheumatoid arthritis
0.487 0.512 0.000
M06.2 Rheumatoid bursitis
0.487 0.512 0.000
M06.1 Adult-onset Still's disease
0.487 0.512 0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.482 0.518 0.000
M06.4 Inflammatory polyarthropathy
0.476 0.524 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.472 0.528 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.531 0.469
K90.9 Intestinal malabsorption, unspecified
0.000 0.539 0.461
E34.9 Endocrine disorder, unspecified
0.000 0.542 0.458
E11 Non-insulin-dependent diabetes mellitus
0.000 0.544 0.456
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.549 0.450
E32 Diseases of thymus
0.000 0.549 0.450
E31 Polyglandular dysfunction
0.000 0.549 0.450
E30 Disorders of puberty, not elsewhere classified
0.000 0.549 0.450
E25 Adrenogenital disorders
0.000 0.549 0.450
E27 Other disorders of adrenal gland
0.000 0.552 0.448
E66.1 Drug-induced obesity
0.000 0.553 0.447
M45-M49 Spondylopathies
0.436 0.564 0.000
M06.37 Rheumatoid nodule (Ankle and foot)
0.435 0.565 0.000
E22 Hyperfunction of pituitary gland
0.000 0.566 0.434
E20 Hypoparathyroidism
0.000 0.567 0.433
E26.0 Primary hyperaldosteronism
0.000 0.569 0.431
M06.39 Rheumatoid nodule (Site unspecified)
0.428 0.572 0.000
M06.38 Rheumatoid nodule (Other)
0.428 0.572 0.000
M06.36 Rheumatoid nodule (Lower leg)
0.428 0.572 0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.428 0.572 0.000
M06.33 Rheumatoid nodule (Forearm)
0.428 0.572 0.000
M06.31 Rheumatoid nodule (Shoulder region)
0.428 0.572 0.000
M06.30 Rheumatoid nodule (Multiple sites)
0.428 0.572 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.573 0.427
M06.08 Seronegative rheumatoid arthritis (Other)
0.425 0.575 0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.425 0.575 0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.425 0.575 0.000
M06.04 Seronegative rheumatoid arthritis (Hand)
0.425 0.575 0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.425 0.575 0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.425 0.575 0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.425 0.575 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.576 0.424
K90.3 Pancreatic steatorrhoea
0.000 0.582 0.418
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.582 0.418
K90.1 Tropical sprue
0.000 0.582 0.418
E27.1 Primary adrenocortical insufficiency
0.000 0.583 0.417
M46 Other inflammatory spondylopathies
0.415 0.585 0.000
E34.0 Carcinoid syndrome
0.000 0.587 0.413
E24.9 Cushing's syndrome, unspecified
0.000 0.588 0.412
E67.8 Other specified hyperalimentation
0.000 0.591 0.408
E67.3 Hypervitaminosis D
0.000 0.591 0.408
E67.2 Megavitamin-B6 syndrome
0.000 0.591 0.408
E67.1 Hypercarotenaemia
0.000 0.591 0.408
E67.0 Hypervitaminosis A
0.000 0.591 0.408
E21.0 Primary hyperparathyroidism
0.000 0.591 0.408
E29 Testicular dysfunction
0.000 0.592 0.408
M46.9 Inflammatory spondylopathy, unspecified
0.399 0.600 0.000
E11.3 With ophthalmic complications
0.000 0.604 0.396
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)
0.393 0.607 0.000
E55 Vitamin D deficiency
0.000 0.610 0.390
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.613 0.387
E63 Other nutritional deficiencies
0.000 0.613 0.387
E56 Other vitamin deficiencies
0.000 0.613 0.387
E51 Thiamine deficiency
0.000 0.613 0.387
E50 Vitamin A deficiency
0.000 0.613 0.387
E60 Dietary zinc deficiency
0.000 0.613 0.387
E59 Dietary selenium deficiency
0.000 0.613 0.387
E54 Ascorbic acid deficiency
0.000 0.613 0.387
E52 Niacin deficiency [pellagra]
0.000 0.613 0.387
E24.0 Pituitary-dependent Cushing's disease
0.000 0.617 0.383
E34.5 Androgen resistance syndrome
0.000 0.618 0.382
E34.4 Constitutional tall stature
0.000 0.618 0.382
E34.3 Short stature, not elsewhere classified
0.000 0.618 0.382
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.618 0.382
E34.1 Other hypersecretion of intestinal hormones
0.000 0.618 0.382
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.373 0.627 0.000
M06.32 Rheumatoid nodule (Upper arm)
0.371 0.628 0.000
E44.1 Mild protein-energy malnutrition
0.000 0.632 0.368
E44.0 Moderate protein-energy malnutrition
0.000 0.632 0.368
E26.9 Hyperaldosteronism, unspecified
0.000 0.632 0.368
E26.8 Other hyperaldosteronism
0.000 0.632 0.368
E26.1 Secondary hyperaldosteronism
0.000 0.632 0.368
E11.8 With unspecified complications
0.000 0.634 0.365
E11.6 With other specified complications
0.000 0.635 0.365
E22.1 Hyperprolactinaemia
0.000 0.637 0.363
K90.8 Other intestinal malabsorption
0.000 0.638 0.362
G37 Other demyelinating diseases of central nervous system
0.000 0.639 0.361
E58 Dietary calcium deficiency
0.000 0.639 0.361
E21.4 Other specified disorders of parathyroid gland
0.000 0.639 0.361
E21.2 Other hyperparathyroidism
0.000 0.639 0.361
E24.8 Other Cushing's syndrome
0.000 0.639 0.361
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.639 0.361
E24.3 Ectopic ACTH syndrome
0.000 0.639 0.361
E24.1 Nelson's syndrome
0.000 0.639 0.361
E34.8 Other specified endocrine disorders
0.000 0.645 0.355
E11.5 With peripheral circulatory complications
0.000 0.645 0.355
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.353 0.646 0.000
M06.19 Adult-onset Still's disease (Site unspecified)
0.350 0.650 0.000
M06.18 Adult-onset Still's disease (Other)
0.350 0.650 0.000
M06.17 Adult-onset Still's disease (Ankle and foot)
0.350 0.650 0.000
M06.16 Adult-onset Still's disease (Lower leg)
0.350 0.650 0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.350 0.650 0.000
M06.14 Adult-onset Still's disease (Hand)
0.350 0.650 0.000
M06.13 Adult-onset Still's disease (Forearm)
0.350 0.650 0.000
M06.12 Adult-onset Still's disease (Upper arm)
0.350 0.650 0.000
M06.11 Adult-onset Still's disease (Shoulder region)
0.350 0.650 0.000
M06.10 Adult-onset Still's disease (Multiple sites)
0.350 0.650 0.000
M06.29 Rheumatoid bursitis (Site unspecified)
0.350 0.650 0.000
M06.28 Rheumatoid bursitis (Other)
0.350 0.650 0.000
M06.27 Rheumatoid bursitis (Ankle and foot)
0.350 0.650 0.000
M06.26 Rheumatoid bursitis (Lower leg)
0.350 0.650 0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.350 0.650 0.000
M06.24 Rheumatoid bursitis (Hand)
0.350 0.650 0.000
M06.23 Rheumatoid bursitis (Forearm)
0.350 0.650 0.000
M06.22 Rheumatoid bursitis (Upper arm)
0.350 0.650 0.000
M06.21 Rheumatoid bursitis (Shoulder region)
0.350 0.650 0.000
M06.20 Rheumatoid bursitis (Multiple sites)
0.350 0.650 0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.350 0.650 0.000
M06.88 Other specified rheumatoid arthritis (Other)
0.350 0.650 0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.350 0.650 0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.350 0.650 0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.350 0.650 0.000
M06.84 Other specified rheumatoid arthritis (Hand)
0.350 0.650 0.000
M06.83 Other specified rheumatoid arthritis (Forearm)
0.350 0.650 0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.350 0.650 0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.350 0.650 0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.350 0.650 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.654 0.346
E07 Other disorders of thyroid
0.001 0.656 0.342
M06.48 Inflammatory polyarthropathy (Other)
0.341 0.659 0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.341 0.659 0.000
M06.46 Inflammatory polyarthropathy (Lower leg)
0.341 0.659 0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.341 0.659 0.000
M06.44 Inflammatory polyarthropathy (Hand)
0.341 0.659 0.000
M06.43 Inflammatory polyarthropathy (Forearm)
0.341 0.659 0.000
M06.42 Inflammatory polyarthropathy (Upper arm)
0.341 0.659 0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.341 0.659 0.000
G36 Other acute disseminated demyelination
0.000 0.664 0.336
E24.2 Drug-induced Cushing's syndrome
0.000 0.664 0.336
E61 Deficiency of other nutrient elements
0.000 0.668 0.332
M46.2 Osteomyelitis of vertebra
0.331 0.669 0.000
E53 Deficiency of other B group vitamins
0.000 0.671 0.329
E21.3 Hyperparathyroidism, unspecified
0.000 0.671 0.329
E11.7 With multiple complications
0.000 0.673 0.327
E22.0 Acromegaly and pituitary gigantism
0.000 0.676 0.324
E25.9 Adrenogenital disorder, unspecified
0.000 0.677 0.323
E25.8 Other adrenogenital disorders
0.000 0.677 0.323
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.677 0.323
E30.9 Disorder of puberty, unspecified
0.000 0.677 0.323
E30.8 Other disorders of puberty
0.000 0.677 0.323
E30.1 Precocious puberty
0.000 0.677 0.323
E30.0 Delayed puberty
0.000 0.677 0.323
E31.9 Polyglandular dysfunction, unspecified
0.000 0.677 0.323
E31.8 Other polyglandular dysfunction
0.000 0.677 0.323
E31.1 Polyglandular hyperfunction
0.000 0.677 0.323
E31.0 Autoimmune polyglandular failure
0.000 0.677 0.323
E32.9 Disease of thymus, unspecified
0.000 0.677 0.323
E32.8 Other diseases of thymus
0.000 0.677 0.323
E32.1 Abscess of thymus
0.000 0.677 0.323
E32.0 Persistent hyperplasia of thymus
0.000 0.677 0.323
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.677 0.323
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.677 0.323
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.677 0.323
E27.5 Adrenomedullary hyperfunction
0.000 0.678 0.321
E27.0 Other adrenocortical overactivity
0.000 0.678 0.321
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.314 0.686 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.688 0.311
E22.8 Other hyperfunction of pituitary gland
0.000 0.688 0.311
E11.1 With ketoacidosis
0.000 0.689 0.311
E20.8 Other hypoparathyroidism
0.000 0.689 0.310
E20.1 Pseudohypoparathyroidism
0.000 0.689 0.310
E20.0 Idiopathic hypoparathyroidism
0.000 0.689 0.310
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.691 0.308
E04 Other non-toxic goitre
0.000 0.693 0.307
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)
0.304 0.696 0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.000 0.696 0.304
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)
0.298 0.702 0.000
M46.8 Other specified inflammatory spondylopathies
0.297 0.702 0.000
M46.5 Other infective spondylopathies
0.297 0.702 0.000
M46.3 Infection of intervertebral disk (pyogenic)
0.297 0.702 0.000
M46.0 Spinal enthesopathy
0.297 0.702 0.000
M49 Spondylopathies in diseases classified elsewhere
0.295 0.705 0.000
E20.9 Hypoparathyroidism, unspecified
0.000 0.707 0.293
E29.9 Testicular dysfunction, unspecified
0.000 0.707 0.293
E29.8 Other testicular dysfunction
0.000 0.707 0.293
E29.0 Testicular hyperfunction
0.000 0.707 0.293
E27.9 Disorder of adrenal gland, unspecified
0.000 0.707 0.292
M46.98 Inflammatory spondylopathy, unspecified (Sacral and sacrococcygeal region)
0.286 0.713 0.000
M46.95 Inflammatory spondylopathy, unspecified (Thoracolumbar region)
0.286 0.713 0.000
M46.94 Inflammatory spondylopathy, unspecified (Thoracic region)
0.286 0.713 0.000
M46.93 Inflammatory spondylopathy, unspecified (Cervicothoracic region)
0.286 0.713 0.000
M46.91 Inflammatory spondylopathy, unspecified (Occipito-atlanto-axial region)
0.286 0.713 0.000
M46.4 Discitis, unspecified
0.286 0.714 0.000
E55.9 Vitamin D deficiency, unspecified
0.000 0.718 0.282
E55.0 Rickets, active
0.000 0.720 0.279
E50.9 Vitamin A deficiency, unspecified
0.000 0.723 0.277
E50.8 Other manifestations of vitamin A deficiency
0.000 0.723 0.277
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.723 0.277
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.723 0.277
E50.5 Vitamin A deficiency with night blindness
0.000 0.723 0.277
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.723 0.277
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.723 0.277
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.723 0.277
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.723 0.277
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.723 0.277
E51.9 Thiamine deficiency, unspecified
0.000 0.723 0.277
E51.8 Other manifestations of thiamine deficiency
0.000 0.723 0.277
E51.2 Wernicke's encephalopathy
0.000 0.723 0.277
E51.1 Beriberi
0.000 0.723 0.277
E56.9 Vitamin deficiency, unspecified
0.000 0.723 0.277
E56.8 Deficiency of other vitamins
0.000 0.723 0.277
E56.1 Deficiency of vitamin K
0.000 0.723 0.277
E56.0 Deficiency of vitamin E
0.000 0.723 0.277
E63.9 Nutritional deficiency, unspecified
0.000 0.723 0.277
E63.8 Other specified nutritional deficiencies
0.000 0.723 0.277
E63.1 Imbalance of constituents of food intake
0.000 0.723 0.277
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.723 0.277
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.723 0.277
E64.8 Sequelae of other nutritional deficiencies
0.000 0.723 0.277
E64.3 Sequelae of rickets
0.000 0.723 0.277
E64.2 Sequelae of vitamin C deficiency
0.000 0.723 0.277
E64.1 Sequelae of vitamin A deficiency
0.000 0.723 0.277
E64.0 Sequelae of protein-energy malnutrition
0.000 0.723 0.277
M46.26 Osteomyelitis of vertebra (Lumbar region)
0.270 0.730 0.000
M46.1 Sacro-iliitis, not elsewhere classified
0.270 0.730 0.000
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)
0.270 0.730 0.000
E11.4 With neurological complications
0.000 0.730 0.270
E03 Other hypothyroidism
0.030 0.732 0.237
E27.8 Other specified disorders of adrenal gland
0.000 0.733 0.267
G37.5 Concentric sclerosis [Balo]
0.000 0.741 0.259
G37.4 Subacute necrotising myelitis
0.000 0.741 0.259
G37.2 Central pontine myelinolysis
0.000 0.741 0.259
G37.1 Central demyelination of corpus callosum
0.000 0.741 0.259
G37.0 Diffuse sclerosis
0.000 0.741 0.259
G37.8 Other specified demyelinating diseases of central nervous system
0.000 0.743 0.257
E53.9 Vitamin B deficiency, unspecified
0.000 0.743 0.257
E11.0 With coma
0.000 0.745 0.255
E29.1 Testicular hypofunction
0.000 0.749 0.250
E27.2 Addisonian crisis
0.000 0.751 0.248
E04.0 Non-toxic diffuse goitre
0.000 0.753 0.247
E07.1 Dyshormogenetic goitre
0.001 0.753 0.246
E07.0 Hypersecretion of calcitonin
0.001 0.753 0.246
G36.9 Acute disseminated demyelination, unspecified
0.000 0.759 0.241
G36.8 Other specified acute disseminated demyelination
0.000 0.759 0.241
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.000 0.759 0.241
G36.0 Neuromyelitis optica [Devic]
0.000 0.759 0.241
E61.9 Deficiency of nutrient element, unspecified
0.000 0.762 0.238
E61.8 Deficiency of other specified nutrient elements
0.000 0.762 0.238
E61.7 Deficiency of multiple nutrient elements
0.000 0.762 0.238
E61.6 Vanadium deficiency
0.000 0.762 0.238
E61.5 Molybdenum deficiency
0.000 0.762 0.238
E61.4 Chromium deficiency
0.000 0.762 0.238
E61.3 Manganese deficiency
0.000 0.762 0.238
E61.0 Copper deficiency
0.000 0.762 0.238
M46.29 Osteomyelitis of vertebra (Site unspecified)
0.237 0.763 0.000
M46.28 Osteomyelitis of vertebra (Sacral and sacrococcygeal region)
0.237 0.763 0.000
M46.27 Osteomyelitis of vertebra (Lumbosacral region)
0.237 0.763 0.000
M46.25 Osteomyelitis of vertebra (Thoracolumbar region)
0.237 0.763 0.000
M46.24 Osteomyelitis of vertebra (Thoracic region)
0.237 0.763 0.000
M46.23 Osteomyelitis of vertebra (Cervicothoracic region)
0.237 0.763 0.000
M46.22 Osteomyelitis of vertebra (Cervical region)
0.237 0.763 0.000
M46.21 Osteomyelitis of vertebra (Occipito-atlanto-axial region)
0.237 0.763 0.000
M46.20 Osteomyelitis of vertebra (Multiple sites in spine)
0.237 0.763 0.000
E53.1 Pyridoxine deficiency
0.000 0.764 0.236
E53.0 Riboflavin deficiency
0.000 0.764 0.236
G37.9 Demyelinating disease of central nervous system, unspecified
0.000 0.772 0.228
E61.2 Magnesium deficiency
0.000 0.775 0.225
E23 Hypofunction and other disorders of pituitary gland
0.000 0.776 0.224
M48 Other spondylopathies
0.223 0.777 0.000
E04.8 Other specified non-toxic goitre
0.000 0.779 0.220
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.785 0.215
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)
0.214 0.786 0.000
E11.2 With renal complications
0.000 0.786 0.214
M46.09 Spinal enthesopathy (Site unspecified)
0.213 0.786 0.000
M46.08 Spinal enthesopathy (Sacral and sacrococcygeal region)
0.213 0.786 0.000
M46.07 Spinal enthesopathy (Lumbosacral region)
0.213 0.786 0.000
M46.06 Spinal enthesopathy (Lumbar region)
0.213 0.786 0.000
M46.05 Spinal enthesopathy (Thoracolumbar region)
0.213 0.786 0.000
M46.04 Spinal enthesopathy (Thoracic region)
0.213 0.786 0.000
M46.03 Spinal enthesopathy (Cervicothoracic region)
0.213 0.786 0.000
M46.02 Spinal enthesopathy (Cervical region)
0.213 0.786 0.000
M46.01 Spinal enthesopathy (Occipito-atlanto-axial region)
0.213 0.786 0.000
M46.00 Spinal enthesopathy (Multiple sites in spine)
0.213 0.786 0.000
M46.39 Infection of intervertebral disc (pyogenic) (Site unspecified)
0.213 0.786 0.000
M46.38 Infection of intervertebral disc (pyogenic) (Sacral and sacrococcygeal region)
0.213 0.786 0.000
M46.37 Infection of intervertebral disc (pyogenic) (Lumbosacral region)
0.213 0.786 0.000
M46.36 Infection of intervertebral disc (pyogenic) (Lumbar region)
0.213 0.786 0.000
M46.35 Infection of intervertebral disc (pyogenic) (Thoracolumbar region)
0.213 0.786 0.000
M46.34 Infection of intervertebral disc (pyogenic) (Thoracic region)
0.213 0.786 0.000
M46.33 Infection of intervertebral disc (pyogenic) (Cervicothoracic region)
0.213 0.786 0.000
M46.32 Infection of intervertebral disc (pyogenic) (Cervical region)
0.213 0.786 0.000
M46.31 Infection of intervertebral disc (pyogenic) (Occipito-atlanto-axial region)
0.213 0.786 0.000
M46.30 Infection of intervertebral disc (pyogenic) (Multiple sites in spine)
0.213 0.786 0.000
M46.59 Other infective spondylopathies (Site unspecified)
0.213 0.786 0.000
M46.58 Other infective spondylopathies (Sacral and sacrococcygeal region)
0.213 0.786 0.000
M46.57 Other infective spondylopathies (Lumbosacral region)
0.213 0.786 0.000
M46.56 Other infective spondylopathies (Lumbar region)
0.213 0.786 0.000
M46.55 Other infective spondylopathies (Thoracolumbar region)
0.213 0.786 0.000
M46.54 Other infective spondylopathies (Thoracic region)
0.213 0.786 0.000
M46.53 Other infective spondylopathies (Cervicothoracic region)
0.213 0.786 0.000
M46.52 Other infective spondylopathies (Cervical region)
0.213 0.786 0.000
M46.51 Other infective spondylopathies (Occipito-atlanto-axial region)
0.213 0.786 0.000
M46.50 Other infective spondylopathies (Multiple sites in spine)
0.213 0.786 0.000
M46.89 Other specified inflammatory spondylopathies (Site unspecified)
0.213 0.786 0.000
M46.88 Other specified inflammatory spondylopathies (Sacral and sacrococcygeal region)
0.213 0.786 0.000
M46.87 Other specified inflammatory spondylopathies (Lumbosacral region)
0.213 0.786 0.000
M46.86 Other specified inflammatory spondylopathies (Lumbar region)
0.213 0.786 0.000
M46.85 Other specified inflammatory spondylopathies (Thoracolumbar region)
0.213 0.786 0.000
M46.84 Other specified inflammatory spondylopathies (Thoracic region)
0.213 0.786 0.000
M46.83 Other specified inflammatory spondylopathies (Cervicothoracic region)
0.213 0.786 0.000
M46.82 Other specified inflammatory spondylopathies (Cervical region)
0.213 0.786 0.000
M46.81 Other specified inflammatory spondylopathies (Occipito-atlanto-axial region)
0.213 0.786 0.000
M46.80 Other specified inflammatory spondylopathies (Multiple sites in spine)
0.213 0.786 0.000
M49.8 Spondylopathy in other diseases classified elsewhere
0.212 0.788 0.000
M49.4 Neuropathic spondylopathy
0.212 0.788 0.000
M49.3 Spondylopathy in other infectious and parasitic diseases classified elsewhere
0.212 0.788 0.000
M49.2 Enterobacterial spondylitis
0.212 0.788 0.000
M49.1 Brucella spondylitis
0.212 0.788 0.000
M49.0 Tuberculosis of spine
0.212 0.788 0.000
M46.46 Discitis, unspecified (Lumbar region)
0.208 0.792 0.000
M46.49 Discitis, unspecified (Site unspecified)
0.205 0.794 0.000
M46.48 Discitis, unspecified (Sacral and sacrococcygeal region)
0.205 0.794 0.000
M46.47 Discitis, unspecified (Lumbosacral region)
0.205 0.794 0.000
M46.45 Discitis, unspecified (Thoracolumbar region)
0.205 0.794 0.000
M46.43 Discitis, unspecified (Cervicothoracic region)
0.205 0.794 0.000
M46.42 Discitis, unspecified (Cervical region)
0.205 0.794 0.000
M46.41 Discitis, unspecified (Occipito-atlanto-axial region)
0.205 0.794 0.000
M46.40 Discitis, unspecified (Multiple sites in spine)
0.205 0.794 0.000
E61.1 Iron deficiency
0.000 0.798 0.202
M46.19 Sacroiliitis, not elsewhere classified-Site unspe
0.194 0.806 0.000
M46.17 Sacroiliitis, not elsewhere classified-Lumbosacral
0.194 0.806 0.000
M46.16 Sacroiliitis, not elsewhere classified-Lumbar
0.194 0.806 0.000
M46.15 Sacroiliitis, not elsewhere classified-Thoracolumbar
0.194 0.806 0.000
M46.14 Sacroiliitis, not elsewhere classified-Thoracic
0.194 0.806 0.000
M46.13 Sacroiliitis, not elsewhere classified-Cervicothoracic
0.194 0.806 0.000
M46.12 Sacroiliitis, not elsewhere classified-Cervical
0.194 0.806 0.000
M46.11 Sacroiliitis, not elsewhere classified-Occipit-atl-axl
0.194 0.806 0.000
M46.10 Sacroiliitis, not elsewhere classified-Mult site
0.194 0.806 0.000
M49.5 Collapsed vertebra in diseases classified elsewhere
0.194 0.806 0.000
E03.5 Myxoedema coma
0.022 0.808 0.170
E03.4 Atrophy of thyroid (acquired)
0.022 0.808 0.170
E03.3 Postinfectious hypothyroidism
0.022 0.808 0.170
E03.1 Congenital hypothyroidism without goitre
0.022 0.808 0.170
E03.0 Congenital hypothyroidism with diffuse goitre
0.022 0.808 0.170
M46.44 Discitis, unspecified (Thoracic region)
0.191 0.809 0.000
E07.8 Other specified disorders of thyroid
0.001 0.809 0.190
E28 Ovarian dysfunction
0.003 0.813 0.184
E04.9 Non-toxic goitre, unspecified
0.000 0.819 0.181
E23.6 Other disorders of pituitary gland
0.000 0.824 0.175
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.830 0.169
M48.8 Other specified spondylopathies
0.168 0.832 0.000
M46.18 Sacroiliitis, not elsewhere classified-Sacral/sacrococ
0.166 0.833 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.024 0.834 0.142
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.839 0.160
E23.1 Drug-induced hypopituitarism
0.000 0.839 0.160
M48.9 Spondylopathy, unspecified
0.160 0.840 0.000
M48.4 Fatigue fracture of vertebra
0.160 0.840 0.000
M48.3 Traumatic spondylopathy
0.160 0.840 0.000
M48.2 Kissing spine
0.160 0.840 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.160 0.840 0.000
E03.8 Other specified hypothyroidism
0.023 0.843 0.134
M49.09 Tuberculosis of spine (Site unspecified)
0.152 0.848 0.000
M49.08 Tuberculosis of spine (Sacral and sacrococcygeal region)
0.152 0.848 0.000
M49.07 Tuberculosis of spine (Lumbosacral region)
0.152 0.848 0.000
M49.06 Tuberculosis of spine (Lumbar region)
0.152 0.848 0.000
M49.05 Tuberculosis of spine (Thoracolumbar region)
0.152 0.848 0.000
M49.04 Tuberculosis of spine (Thoracic region)
0.152 0.848 0.000
M49.03 Tuberculosis of spine (Cervicothoracic region)
0.152 0.848 0.000
M49.02 Tuberculosis of spine (Cervical region)
0.152 0.848 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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