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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs9295990
log Bayes Factor = 22.3458
Chromosome 6   position 31,386,019  (GRCh37) Explore rs9295990 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
# Top node
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
L40-L45 Papulosquamous disorders
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
M05-M14 Inflammatory polyarthropathies
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.001 0.999
L40.5 Arthropathic psoriasis
0.000 0.001 0.999
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.001 0.999
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.001 0.999
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.002 0.998
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.003 0.997
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.006 0.994
L57 Skin changes due to chronic exposure to nonionising radiation
0.000 0.011 0.989
L00-L08 Infections of the skin and subcutaneous tissue
0.000 0.013 0.987
D50-D53 Nutritional anaemias
0.000 0.016 0.984
E10.9 Without complications
0.000 0.017 0.983
D50 Iron deficiency anaemia
0.000 0.020 0.980
L57.0 Actinic keratosis
0.000 0.021 0.979
D50.9 Iron deficiency anaemia, unspecified
0.000 0.023 0.977
E10.3 With ophthalmic complications
0.000 0.025 0.975
L02 Cutaneous abscess, furuncle and carbuncle
0.000 0.028 0.972
M07 Psoriatic and enteropathic arthropathies
0.000 0.033 0.967
Chapter I Certain infectious and parasitic diseases
0.000 0.034 0.966
C44 Other malignant neoplasms of skin
0.000 0.042 0.958
C44.3 Skin of other and unspecified parts of face
0.000 0.045 0.955
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.000 0.053 0.947
C43-C44 Melanoma and other malignant neoplasms of skin
0.000 0.055 0.945
M07.3 Other psoriatic arthropathies
0.000 0.057 0.943
C44.4 Skin of scalp and neck
0.000 0.058 0.942
Chapter II Neoplasms
0.000 0.059 0.941
B25-B34 Other viral diseases
0.000 0.063 0.937
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.065 0.935
L08 Other local infections of skin and subcutaneous tissue
0.000 0.069 0.931
D60-D64 Aplastic and other anaemias
0.000 0.069 0.931
L20-L30 Dermatitis and eczema
0.000 0.071 0.929
B35-B49 Mycoses
0.000 0.071 0.929
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.000 0.072 0.928
L57.8 Other skin changes due to chronic exposure to nonionising radiation
0.000 0.075 0.925
E50-E64 Other nutritional deficiencies
0.000 0.080 0.920
M20-M25 Other joint disorders
0.000 0.086 0.914
M35 Other systemic involvement of connective tissue
0.000 0.087 0.913
E10.1 With ketoacidosis
0.000 0.088 0.912
M06.0 Seronegative rheumatoid arthritis
0.000 0.089 0.911
B37 Candidiasis
0.000 0.090 0.910
B34 Viral infection of unspecified site
0.000 0.093 0.907
E06 Thyroiditis
0.000 0.093 0.907
E65-E68 Obesity and other hyperalimentation
0.000 0.096 0.904
M35.3 Polymyalgia rheumatica
0.000 0.097 0.903
B37.8 Candidiasis of other sites
0.000 0.099 0.901
R47-R49 Symptoms and signs involving speech and voice
0.000 0.099 0.901
D64 Other anaemias
0.000 0.100 0.900
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.000 0.105 0.895
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.105 0.895
D80-D89 Certain disorders involving the immune mechanism
0.000 0.109 0.891
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.000 0.111 0.889
B34.9 Viral infection, unspecified
0.000 0.114 0.886
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.000 0.115 0.885
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.000 0.115 0.885
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.000 0.116 0.884
R41 Other symptoms and signs involving cognitive functions and awareness
0.000 0.118 0.882
D64.9 Anaemia, unspecified
0.000 0.123 0.877
C44.1 Skin of eyelid, including canthus
0.000 0.124 0.876
R41.0 Disorientation, unspecified
0.000 0.139 0.861
R47 Speech disturbances, not elsewhere classified
0.000 0.140 0.860
M05 Seropositive rheumatoid arthritis
0.000 0.141 0.859
C64-C68 Malignant neoplasms of urinary tract
0.000 0.142 0.858
M45-M49 Spondylopathies
0.000 0.143 0.857
Chapter IX Diseases of the circulatory system
0.000 0.143 0.857
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.000 0.144 0.856
Chapter VIII Diseases of the ear and mastoid process
0.000 0.148 0.852
E10.4 With neurological complications
0.000 0.150 0.850
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.150 0.850
E53 Deficiency of other B group vitamins
0.000 0.150 0.850
E66 Obesity
0.000 0.152 0.847
I60-I69 Cerebrovascular diseases
0.000 0.153 0.847
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.000 0.153 0.847
L29 Pruritus
0.000 0.155 0.845
E14 Unspecified diabetes mellitus
0.000 0.156 0.844
R41.3 Other amnesia
0.000 0.156 0.844
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.000 0.162 0.838
E06.3 Autoimmune thyroiditis
0.000 0.163 0.837
E66.8 Other obesity
0.000 0.163 0.837
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.165 0.835
R26 Abnormalities of gait and mobility
0.000 0.166 0.834
M45 Ankylosing spondylitis
0.000 0.168 0.832
D86 Sarcoidosis
0.000 0.171 0.829
R91 Abnormal findings on diagnostic imaging of lung
0.000 0.177 0.823
R47.0 Dysphasia and aphasia
0.000 0.180 0.820
M35.0 Sicca syndrome [Sjogren]
0.000 0.180 0.820
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.184 0.816
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.186 0.814
M95.0 Acquired deformity of nose
0.000 0.187 0.813
L40.0 Psoriasis vulgaris
0.000 0.188 0.812
R93 Abnormal findings on diagnostic imaging of other body structures
0.000 0.190 0.810
C44.7 Skin of lower limb, including hip
0.000 0.192 0.808
I60 Subarachnoid haemorrhage
0.000 0.194 0.806
L30 Other dermatitis
0.000 0.194 0.806
B35 Dermatophytosis
0.000 0.196 0.804
C34 Malignant neoplasm of bronchus and lung
0.000 0.200 0.800
E53.8 Deficiency of other specified B group vitamins
0.000 0.200 0.800
L29.0 Pruritus ani
0.000 0.201 0.799
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.201 0.799
B99-B99 Other infectious diseases
0.000 0.207 0.793
M22 Disorders of patella
0.000 0.208 0.792
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract
0.000 0.208 0.792
R26.8 Other and unspecified abnormalities of gait and mobility
0.000 0.209 0.791
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock
0.000 0.210 0.790
E10.5 With peripheral circulatory complications
0.000 0.216 0.784
H65-H75 Diseases of middle ear and mastoid
0.000 0.217 0.783
R49 Voice disturbances
0.000 0.219 0.781
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.220 0.780
I63 Cerebral infarction
0.000 0.227 0.773
E10.2 With renal complications
0.000 0.228 0.772
R47.1 Dysarthria and anarthria
0.000 0.229 0.771
C67 Malignant neoplasm of bladder
0.000 0.230 0.770
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.000 0.231 0.769
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.000 0.233 0.767
I69 Sequelae of cerebrovascular disease
0.000 0.236 0.764
D86.9 Sarcoidosis, unspecified
0.000 0.238 0.762
I67 Other cerebrovascular diseases
0.000 0.239 0.761
M00-M03 Infectious arthropathies
0.000 0.239 0.761
C34.9 Bronchus or lung, unspecified
0.000 0.239 0.761
H72 Perforation of tympanic membrane
0.000 0.240 0.760
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.242 0.758
M60-M63 Disorders of muscles
0.000 0.246 0.754
B20-B24 Human immunodeficiency virus [HIV] disease
0.000 0.247 0.753
B25 Cytomegaloviral disease
0.000 0.249 0.751
M34 Systemic sclerosis
0.000 0.251 0.749
I05-I09 Chronic rheumatic heart diseases
0.000 0.254 0.746
M35.7 Hypermobility syndrome
0.000 0.255 0.745
E55 Vitamin D deficiency
0.000 0.258 0.742
C44.2 Skin of ear and external auricular canal
0.000 0.259 0.741
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.259 0.741
H72.9 Perforation of tympanic membrane, unspecified
0.000 0.262 0.738
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum
0.000 0.262 0.738
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.000 0.263 0.737
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.000 0.265 0.735
D55-D59 Haemolytic anaemias
0.000 0.266 0.734
I63.9 Cerebral infarction, unspecified
0.000 0.267 0.733
E14.9 Without complications
0.000 0.271 0.729
B37.0 Candidal stomatitis
0.000 0.273 0.727
I67.8 Other specified cerebrovascular diseases
0.000 0.274 0.726
R41.2 Retrograde amnesia
0.000 0.277 0.723
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.278 0.722
L40.8 Other psoriasis
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.000 0.283 0.717
L40.3 Pustulosis palmaris et plantaris
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
L40.1 Generalised pustular psoriasis
0.000 0.283 0.717
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.283 0.717
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.283 0.717
L44 Other papulosquamous disorders
0.000 0.283 0.717
L41 Parapsoriasis
0.000 0.283 0.717
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
M06.8 Other specified rheumatoid arthritis
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
M12 Other specific arthropathies
0.000 0.283 0.717
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.717
M08 Juvenile arthritis
0.000 0.283 0.717
E10.8 With unspecified complications
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E10.0 With coma
0.000 0.283 0.717
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.000 0.286 0.714
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.000 0.288 0.712
L58 Radiodermatitis
0.000 0.288 0.712
L55 Sunburn
0.000 0.288 0.712
E40-E46 Malnutrition
0.000 0.288 0.712
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.000 0.291 0.709
L57.5 Actinic granuloma
0.000 0.291 0.709
L57.3 Poikiloderma of Civatte
0.000 0.291 0.709
L57.2 Cutis rhomboidalis nuchae
0.000 0.291 0.709
L57.1 Actinic reticuloid
0.000 0.291 0.709
R26.2 Difficulty in walking, not elsewhere classified
0.000 0.291 0.709
A50-A64 Infections with a predominantly sexual mode of transmission
0.000 0.292 0.708
L04 Acute lymphadenitis
0.000 0.292 0.708
L01 Impetigo
0.000 0.292 0.708
L00 Staphylococcal scalded skin syndrome
0.000 0.292 0.708
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.293 0.707
R90 Abnormal findings on diagnostic imaging of central nervous system
0.000 0.295 0.705
L56 Other acute skin changes due to ultraviolet radiation
0.000 0.295 0.705
Chapter XXII Codes for special purposes
0.000 0.295 0.705
M46 Other inflammatory spondylopathies
0.000 0.296 0.704
A30-A49 Other bacterial diseases
0.000 0.296 0.704
D50.1 Sideropenic dysphagia
0.000 0.297 0.702
D86.0 Sarcoidosis of lung
0.000 0.298 0.702
I62 Other nontraumatic intracranial haemorrhage
0.000 0.298 0.702
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites
0.000 0.303 0.697
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.000 0.303 0.697
L30.8 Other specified dermatitis
0.000 0.305 0.695
L27 Dermatitis due to substances taken internally
0.000 0.305 0.695
M14 Arthropathies in other diseases classified elsewhere
0.000 0.305 0.694
E13 Other specified diabetes mellitus
0.000 0.306 0.694
M07.6 Other enteropathic arthropathies
0.000 0.307 0.693
M07.5 Arthropathy in ulcerative colitis
0.000 0.307 0.693
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.307 0.693
M07.2 Psoriatic spondylitis
0.000 0.307 0.693
M07.1 Arthritis mutilans
0.000 0.307 0.693
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.307 0.693
B85-B89 Pediculosis, acariasis and other infestations
0.000 0.307 0.693
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.000 0.307 0.693
A75-A79 Rickettsioses
0.000 0.307 0.693
A70-A74 Other diseases caused by chlamydiae
0.000 0.307 0.693
A65-A69 Other spirochaetal diseases
0.000 0.307 0.693
A20-A28 Certain zoonotic bacterial diseases
0.000 0.307 0.693
C67.2 Lateral wall of bladder
0.000 0.308 0.692
L05 Pilonidal cyst
0.000 0.309 0.690
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.310 0.690
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.000 0.311 0.689
L10-L14 Bullous disorders
0.000 0.311 0.689
B50-B64 Protozoal diseases
0.000 0.312 0.688
M11 Other crystal arthropathies
0.000 0.312 0.687
C44.8 Overlapping lesion of skin
0.000 0.313 0.686
I69.3 Sequelae of cerebral infarction
0.000 0.317 0.683
E03.8 Other specified hypothyroidism
0.000 0.318 0.682
R26.3 Immobility
0.000 0.318 0.682
I73 Other peripheral vascular diseases
0.000 0.319 0.681
A15-A19 Tuberculosis
0.000 0.321 0.679
L08.8 Other specified local infections of skin and subcutaneous tissue
0.000 0.322 0.678
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.000 0.323 0.677
R49.0 Dysphonia
0.000 0.323 0.677
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.324 0.676
M07.38 Other psoriatic arthropathies (Other)
0.000 0.324 0.676
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.324 0.676
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.324 0.676
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.324 0.676
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.324 0.676
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.324 0.676
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.324 0.676
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.324 0.676
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.324 0.676
B35.1 Tinea unguium
0.000 0.325 0.675
B33 Other viral diseases, not elsewhere classified
0.000 0.328 0.672
B30 Viral conjunctivitis
0.000 0.328 0.672
B27 Infectious mononucleosis
0.000 0.328 0.672
B26 Mumps
0.000 0.328 0.672
H72.0 Central perforation of tympanic membrane
0.000 0.329 0.671
D61 Other aplastic anaemias
0.000 0.329 0.671
B99 Other and unspecified infectious diseases
0.000 0.330 0.670
I20-I25 Ischaemic heart diseases
0.000 0.330 0.670
C66 Malignant neoplasm of ureter
0.000 0.332 0.668
L08.1 Erythrasma
0.000 0.332 0.668
L08.0 Pyoderma
0.000 0.332 0.668
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.333 0.667
M22.8 Other disorders of patella
0.000 0.333 0.667
L24 Irritant contact dermatitis
0.000 0.334 0.666
L21 Seborrhoeic dermatitis
0.000 0.334 0.666
L26 Exfoliative dermatitis
0.000 0.334 0.666
L22 Diaper [napkin] dermatitis
0.000 0.334 0.666
B48 Other mycoses, not elsewhere classified
0.000 0.334 0.666
B47 Mycetoma
0.000 0.334 0.666
B46 Zygomycosis
0.000 0.334 0.666
B45 Cryptococcosis
0.000 0.334 0.666
B43 Chromomycosis and phaeomycotic abscess
0.000 0.334 0.666
B42 Sporotrichosis
0.000 0.334 0.666
B41 Paracoccidioidomycosis
0.000 0.334 0.666
B40 Blastomycosis
0.000 0.334 0.666
B39 Histoplasmosis
0.000 0.334 0.666
B38 Coccidioidomycosis
0.000 0.334 0.666
B36 Other superficial mycoses
0.000 0.334 0.666
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.334 0.666
R95-R99 Ill-defined and unknown causes of mortality
0.000 0.334 0.665
L28 Lichen simplex chronicus and prurigo
0.000 0.335 0.665
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified
0.000 0.337 0.663
E06.9 Thyroiditis, unspecified
0.000 0.338 0.662
I60.8 Other subarachnoid haemorrhage
0.000 0.340 0.660
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.341 0.659
E63 Other nutritional deficiencies
0.000 0.341 0.659
E56 Other vitamin deficiencies
0.000 0.341 0.659
E51 Thiamine deficiency
0.000 0.341 0.659
E50 Vitamin A deficiency
0.000 0.341 0.659
E60 Dietary zinc deficiency
0.000 0.341 0.659
E59 Dietary selenium deficiency
0.000 0.341 0.659
E58 Dietary calcium deficiency
0.000 0.341 0.659
E54 Ascorbic acid deficiency
0.000 0.341 0.659
E52 Niacin deficiency [pellagra]
0.000 0.341 0.659
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.000 0.341 0.659
I05 Rheumatic mitral valve diseases
0.000 0.342 0.658
I73.0 Raynaud's syndrome
0.000 0.342 0.658
B65-B83 Helminthiases
0.000 0.342 0.658
M06.3 Rheumatoid nodule
0.000 0.343 0.657
E10.6 With other specified complications
0.000 0.344 0.656
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.000 0.344 0.655
M32 Systemic lupus erythematosus
0.000 0.344 0.655
D64.8 Other specified anaemias
0.000 0.345 0.655
H80-H83 Diseases of inner ear
0.000 0.345 0.655
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.346 0.654
M35.8 Other specified systemic involvement of connective tissue
0.000 0.346 0.654
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.346 0.654
M35.5 Multifocal fibrosclerosis
0.000 0.346 0.654
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.346 0.654
M35.2 Behcet's disease
0.000 0.346 0.654
M35.1 Other overlap syndromes
0.000 0.346 0.654
L29.9 Pruritus, unspecified
0.000 0.346 0.654
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.347 0.653
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.347 0.653
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.347 0.653
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.347 0.653
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.347 0.653
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.347 0.653
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.347 0.653
B37.7 Candidal septicaemia
0.000 0.348 0.652
B37.6 Candidal endocarditis
0.000 0.348 0.652
B37.5 Candidal meningitis
0.000 0.348 0.652
B37.2 Candidiasis of skin and nail
0.000 0.348 0.652
C65 Malignant neoplasm of renal pelvis
0.000 0.349 0.651
B34.8 Other viral infections of unspecified site
0.000 0.350 0.650
B34.4 Papovirus infection, unspecified
0.000 0.350 0.650
B34.3 Parvovirus infection, unspecified
0.000 0.350 0.650
B34.2 Coronavirus infection, unspecified
0.000 0.350 0.650
B34.1 Enterovirus infection, unspecified
0.000 0.350 0.650
B34.0 Adenovirus infection, unspecified
0.000 0.350 0.650
E06.5 Other chronic thyroiditis
0.000 0.350 0.650
E06.4 Drug-induced thyroiditis
0.000 0.350 0.650
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.350 0.650
E06.1 Subacute thyroiditis
0.000 0.350 0.650
E06.0 Acute thyroiditis
0.000 0.350 0.650
I21 Acute myocardial infarction
0.000 0.351 0.649
C44.6 Skin of upper limb, including shoulder
0.000 0.351 0.648
E67 Other hyperalimentation
0.000 0.352 0.648
E68 Sequelae of hyperalimentation
0.000 0.352 0.648
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.352 0.647
M30 Polyarteritis nodosa and related conditions
0.000 0.352 0.647
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.000 0.353 0.647
I60.9 Subarachnoid haemorrhage, unspecified
0.000 0.353 0.647
A80-A89 Viral infections of the central nervous system
0.000 0.353 0.647
C73 Malignant neoplasm of thyroid gland
0.000 0.354 0.646
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified
0.000 0.354 0.646
B35.3 Tinea pedis
0.000 0.354 0.646
D64.4 Congenital dyserythropoietic anaemia
0.000 0.355 0.645
D64.3 Other sideroblastic anaemias
0.000 0.355 0.645
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.000 0.355 0.645
D64.1 Secondary sideroblastic anaemia due to disease
0.000 0.355 0.645
D64.0 Hereditary sideroblastic anaemia
0.000 0.355 0.645
I77 Other disorders of arteries and arterioles
0.000 0.356 0.644
E20-E35 Disorders of other endocrine glands
0.000 0.357 0.643
M99 Biomechanical lesions, not elsewhere classified
0.000 0.358 0.642
L20 Atopic dermatitis
0.000 0.359 0.641
R87 Abnormal findings in specimens from female genital organs
0.000 0.360 0.640
C40-C41 Malignant neoplasms of bone and articular cartilage
0.000 0.361 0.639
R27 Other lack of coordination
0.000 0.361 0.639
D84 Other immunodeficiencies
0.000 0.361 0.638
D83 Common variable immunodeficiency
0.000 0.361 0.638
D82 Immunodeficiency associated with other major defects
0.000 0.361 0.638
D81 Combined immunodeficiencies
0.000 0.361 0.638
L25 Unspecified contact dermatitis
0.000 0.362 0.638
I08 Multiple valve diseases
0.000 0.362 0.638
B90-B94 Sequelae of infectious and parasitic diseases
0.000 0.363 0.637
M31 Other necrotising vasculopathies
0.000 0.363 0.637
C79 Secondary malignant neoplasm of other sites
0.000 0.365 0.635
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.000 0.365 0.634
D53 Other nutritional anaemias
0.000 0.366 0.634
R41.1 Anterograde amnesia
0.000 0.367 0.632
B37.1 Pulmonary candidiasis
0.000 0.368 0.632
L57.4 Cutis laxa senilis
0.000 0.368 0.632
M06.4 Inflammatory polyarthropathy
0.000 0.369 0.631
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.000 0.369 0.631
M34.9 Systemic sclerosis, unspecified
0.000 0.370 0.630
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.000 0.371 0.629
M46.9 Inflammatory spondylopathy, unspecified
0.000 0.372 0.628
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.373 0.627
E66.0 Obesity due to excess calories
0.000 0.373 0.627
C34.1 Upper lobe, bronchus or lung
0.000 0.373 0.627
H60-H62 Diseases of external ear
0.000 0.374 0.626
M22.2 Patellofemoral disorders
0.000 0.374 0.626
D63 Anaemia in chronic diseases classified elsewhere
0.000 0.374 0.626
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.000 0.375 0.625
D80 Immunodeficiency with predominantly antibody defects
0.000 0.375 0.624
L50-L54 Urticaria and erythema
0.000 0.377 0.623
E11 Non-insulin-dependent diabetes mellitus
0.000 0.377 0.623
L23 Allergic contact dermatitis
0.000 0.377 0.623
L30.9 Dermatitis, unspecified
0.000 0.377 0.623
H65 Nonsuppurative otitis media
0.000 0.379 0.621
M22.3 Other derangements of patella
0.000 0.380 0.620
L02.0 Cutaneous abscess, furuncle and carbuncle of face
0.000 0.381 0.619
C34.3 Lower lobe, bronchus or lung
0.000 0.381 0.619
C71 Malignant neoplasm of brain
0.000 0.382 0.618
Chapter V Mental and behavioural disorders
0.000 0.382 0.618
B25.9 Cytomegaloviral disease, unspecified
0.000 0.383 0.617
M05.8 Other seropositive rheumatoid arthritis
0.000 0.384 0.616
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.384 0.616
M05.2 Rheumatoid vasculitis
0.000 0.384 0.616
M05.1 Rheumatoid lung disease
0.000 0.384 0.616
M05.0 Felty's syndrome
0.000 0.384 0.616
E55.9 Vitamin D deficiency, unspecified
0.000 0.385 0.615
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract
0.000 0.385 0.615
D51 Vitamin B12 deficiency anaemia
0.000 0.385 0.615
C68 Malignant neoplasm of other and unspecified urinary organs
0.000 0.385 0.615
I00-I02 Acute rheumatic fever
0.000 0.385 0.615
M80-M85 Disorders of bone density and structure
0.001 0.388 0.611
D50.8 Other iron deficiency anaemias
0.000 0.388 0.612
C44.9 Malignant neoplasm of skin, unspecified
0.000 0.389 0.611
C64 Malignant neoplasm of kidney, except renal pelvis
0.000 0.389 0.611
C67.9 Bladder, unspecified
0.000 0.389 0.611
E14.3 With ophthalmic complications
0.000 0.390 0.610
C67.1 Dome of bladder
0.000 0.390 0.610
D52 Folate deficiency anaemia
0.000 0.390 0.610
E53.9 Vitamin B deficiency, unspecified
0.000 0.391 0.609
E53.1 Pyridoxine deficiency
0.000 0.391 0.609
E53.0 Riboflavin deficiency
0.000 0.391 0.609
R46 Symptoms and signs involving appearance and behaviour
0.000 0.391 0.609
E66.1 Drug-induced obesity
0.000 0.392 0.608
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.392 0.608
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.000 0.392 0.608
M95.9 Acquired deformity of musculoskeletal system, unspecified
0.000 0.393 0.607
M95.8 Other specified acquired deformities of musculoskeletal system
0.000 0.393 0.607
M95.5 Acquired deformity of pelvis
0.000 0.393 0.607
M95.4 Acquired deformity of chest and rib
0.000 0.393 0.607
M95.3 Acquired deformity of neck
0.000 0.393 0.607
M95.2 Other acquired deformity of head
0.000 0.393 0.607
M95.1 Cauliflower ear
0.000 0.393 0.607
M33 Dermatopolymyositis
0.000 0.394 0.606
B15-B19 Viral hepatitis
0.000 0.394 0.606
C67.4 Posterior wall of bladder
0.000 0.394 0.606
L29.8 Other pruritus
0.000 0.394 0.606
L29.3 Anogenital pruritus, unspecified
0.000 0.394 0.606
L29.1 Pruritus scroti
0.000 0.394 0.606
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.000 0.394 0.606
E14.8 With unspecified complications
0.000 0.395 0.605
E14.7 With multiple complications
0.000 0.395 0.605
E14.6 With other specified complications
0.000 0.395 0.605
E14.5 With peripheral circulatory complications
0.000 0.395 0.605
E14.4 With neurological complications
0.000 0.395 0.605
E14.2 Withrenal complications
0.000 0.395 0.605
E14.1 With ketoacidosis
0.000 0.395 0.605
E14.0 With coma
0.000 0.395 0.605
E61 Deficiency of other nutrient elements
0.000 0.395 0.605
R87.6 Abnormal cytological findings
0.000 0.395 0.605
E27 Other disorders of adrenal gland
0.000 0.396 0.604
L42 Pityriasis rosea
0.000 0.397 0.603
M49 Spondylopathies in diseases classified elsewhere
0.000 0.398 0.602
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.000 0.399 0.601
C31 Malignant neoplasm of accessory sinuses
0.000 0.399 0.601
C30 Malignant neoplasm of nasal cavity and middle ear
0.000 0.399 0.601
C37 Malignant neoplasm of thymus
0.000 0.399 0.601
C33 Malignant neoplasm of trachea
0.000 0.399 0.601
B24 Unspecified human immunodeficiency virus [HIV] disease
0.000 0.399 0.601
M62 Other disorders of muscle
0.000 0.400 0.599
R49.8 Other and unspecified voice disturbances
0.000 0.401 0.599
H73 Other disorders of tympanic membrane
0.000 0.401 0.599
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.401 0.599
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.000 0.401 0.599
R26.1 Paralytic gait
0.000 0.402 0.598
A41 Other septicaemia
0.000 0.403 0.597
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.000 0.403 0.597
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.000 0.403 0.597
M45.X6 Ankylosing spondylitis (Lumbar region)
0.000 0.403 0.597
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.000 0.403 0.597
M45.X4 Ankylosing spondylitis (Thoracic region)
0.000 0.403 0.597
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.000 0.403 0.597
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.403 0.597
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.000 0.403 0.597
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.403 0.597
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.404 0.596
B37.3 Candidiasis of vulva and vagina
0.000 0.404 0.596
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.000 0.405 0.595
D86.3 Sarcoidosis of skin
0.000 0.405 0.594
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.000 0.405 0.594
D86.1 Sarcoidosis of lymph nodes
0.000 0.405 0.594
E65 Localised adiposity
0.000 0.406 0.594
I21.9 Acute myocardial infarction, unspecified
0.000 0.406 0.594
I77.1 Stricture of artery
0.000 0.406 0.594
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.000 0.406 0.594
E05.9 Thyrotoxicosis, unspecified
0.000 0.408 0.592
M00 Pyogenic arthritis
0.000 0.409 0.591
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.000 0.410 0.590
M91-M94 Chondropathies
0.000 0.411 0.589
R43 Disturbances of smell and taste
0.000 0.414 0.586
I67.2 Cerebral atherosclerosis
0.000 0.415 0.585
E11.3 With ophthalmic complications
0.000 0.416 0.584
R26.0 Ataxic gait
0.000 0.416 0.584
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.000 0.417 0.583
I05.9 Mitral valve disease, unspecified
0.000 0.419 0.581
B37.4 Candidiasis of other urogenital sites
0.000 0.419 0.581
R90.0 Intracranial space-occupying lesion
0.000 0.419 0.581
R93.6 Abnormal findings on diagnostic imaging of limbs
0.000 0.419 0.581
E70-E90 Metabolic disorders
0.000 0.420 0.580
D10-D36 Benign neoplasms
0.000 0.421 0.579
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.000 0.422 0.578
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.000 0.422 0.578
I60.5 Subarachnoid haemorrhage from vertebral artery
0.000 0.422 0.578
I60.4 Subarachnoid haemorrhage from basilar artery
0.000 0.422 0.578
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.000 0.422 0.578

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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