TreeWAS – Variant ID: rs9308433

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
D27 Benign neoplasm of ovary	0.076	0.924	0.000
K57.3 Diverticular disease of large intestine without perforation or abscess	0.024	0.976	0.000
R44 Other symptoms and signs involving general sensations and perceptions	0.021	0.979	0.000
R44.3 Hallucinations, unspecified	0.020	0.980	0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness	0.020	0.980	0.000
R40 Somnolence, stupor and coma	0.019	0.981	0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.019	0.981	0.000
R44.1 Visual hallucinations	0.019	0.981	0.000
R41 Other symptoms and signs involving cognitive functions and awareness	0.018	0.982	0.000
R44.8 Other and unspecified symptoms and signs involving general sensations and perceptions	0.018	0.982	0.000
R40.0 Somnolence	0.018	0.982	0.000
R41.2 Retrograde amnesia	0.018	0.982	0.000
R40.2 Coma, unspecified	0.017	0.983	0.000
R44.2 Other hallucinations	0.016	0.984	0.000
R45 Symptoms and signs involving emotional state	0.016	0.984	0.000
R46 Symptoms and signs involving appearance and behaviour	0.015	0.985	0.000
R45.2 Unhappiness	0.015	0.985	0.000
M21.16 Varus deformity, not elsewhere classified (Lower leg)	0.000	0.986	0.014
R45.6 Physical violence	0.014	0.986	0.000
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.000	0.986	0.014
R45.4 Irritability and anger	0.013	0.987	0.000
R46.8 Other symptoms and signs involving appearance and behaviour	0.013	0.987	0.000
R41.1 Anterograde amnesia	0.013	0.987	0.000
R40.1 Stupor	0.012	0.988	0.000
R45.8 Other symptoms and signs involving emotional state	0.012	0.988	0.000
R45.7 State of emotional shock and stress, unspecified	0.012	0.988	0.000
R46.4 Slowness and poor responsiveness	0.012	0.988	0.000
R45.3 Demoralisation and apathy	0.012	0.988	0.000
R45.5 Hostility	0.012	0.988	0.000
M21.3 Wrist or foot drop (acquired)	0.000	0.989	0.011
R46.7 Verbosity and circumstantial detail obscuring reason for contact	0.011	0.989	0.000
R46.6 Undue concern and preoccupation with stressful events	0.011	0.989	0.000
R46.5 Suspiciousness and marked evasiveness	0.011	0.989	0.000
R46.3 Overactivity	0.011	0.989	0.000
R46.1 Bizarre personal appearance	0.011	0.989	0.000
M21.1 Varus deformity, not elsewhere classified	0.000	0.989	0.011
R46.2 Strange and inexplicable behaviour	0.010	0.990	0.000
R46.0 Very low level of personal hygiene	0.010	0.990	0.000
F32.9 Depressive episode, unspecified	0.010	0.990	0.000
R43 Disturbances of smell and taste	0.009	0.990	0.000
M21 Other acquired deformities of limbs	0.000	0.990	0.010
R41.3 Other amnesia	0.009	0.991	0.000
M21.2 Flexion deformity	0.000	0.991	0.009
R44.0 Auditory hallucinations	0.008	0.991	0.000
M21.27 Flexion deformity (Ankle and foot)	0.000	0.991	0.009
K57 Diverticular disease of intestine	0.008	0.992	0.000
M21.39 Wrist or foot drop (acquired)-Site unspec	0.000	0.992	0.008
M21.38 Wrist or foot drop (acquired)-Other	0.000	0.992	0.008
M21.36 Wrist or foot drop (acquired)-Lower leg	0.000	0.992	0.008
M21.35 Wrist or foot drop (acquired)-Pelvic/thigh	0.000	0.992	0.008
M21.34 Wrist or foot drop (acquired) (Hand)	0.000	0.992	0.008
M21.32 Wrist or foot drop (acquired)-Upper arm	0.000	0.992	0.008
M21.31 Wrist or foot drop (acquired)-Shldr region	0.000	0.992	0.008
M21.30 Wrist or foot drop (acquired) (Multiple sites)	0.000	0.992	0.008
K57.8 Diverticular disease of intestine, part unspecified, with perforation and abscess	0.008	0.992	0.000
M21.19 Varus deformity, not elsewhere classified (Site unspecified)	0.000	0.992	0.008
M21.18 Varus deformity, not elsewhere classified (Other)	0.000	0.992	0.008
M21.15 Varus deformity, not elsewhere classified (Pelvic region and thigh)	0.000	0.992	0.008
M21.14 Varus deformity, not elsewhere classified (Hand)	0.000	0.992	0.008
M21.13 Varus deformity, not elsewhere classified (Forearm)	0.000	0.992	0.008
M21.12 Varus deformity, not elsewhere classified (Upper arm)	0.000	0.992	0.008
M21.11 Varus deformity, not elsewhere classified (Shoulder region)	0.000	0.992	0.008
M21.10 Varus deformity, not elsewhere classified (Multiple sites)	0.000	0.992	0.008
E55.9 Vitamin D deficiency, unspecified	0.008	0.992	0.000
R45.1 Restlessness and agitation	0.008	0.992	0.000
K57.9 Diverticular disease of intestine, part unspecified, without perforation or abscess	0.008	0.992	0.000
R45.0 Nervousness	0.008	0.992	0.000
M21.25 Flexion deformity (Pelvic region and thigh)	0.000	0.992	0.008
R43.2 Parageusia	0.007	0.992	0.000
M21.33 Wrist or foot drop (acquired) (Forearm)	0.000	0.992	0.007
R43.1 Parosmia	0.007	0.992	0.000
M21.8 Other specified acquired deformities of limbs	0.000	0.993	0.007
M21.26 Flexion deformity (Lower leg)	0.000	0.993	0.007
M21.4 Flat foot [pes planus] (acquired)	0.000	0.993	0.007
M21.24 Flexion deformity (Hand)	0.000	0.993	0.007
M21.7 Unequal limb length (acquired)	0.000	0.993	0.007
M21.0 Valgus deformity, not elsewhere classified	0.000	0.993	0.007
M21.29 Flexion deformity (Site unspecified)	0.000	0.993	0.007
M21.28 Flexion deformity (Other)	0.000	0.993	0.007
M21.23 Flexion deformity (Forearm)	0.000	0.993	0.007
M21.21 Flexion deformity (Shoulder region)	0.000	0.993	0.007
M21.20 Flexion deformity (Multiple sites)	0.000	0.993	0.007
I42.9 Cardiomyopathy, unspecified	0.007	0.993	0.000
G80.9 Infantile cerebral palsy, unspecified	0.000	0.993	0.007
G51.0 Bell's palsy	0.000	0.994	0.006
M21.9 Acquired deformity of limb, unspecified	0.000	0.994	0.006
M22.4 Chondromalacia patellae	0.000	0.994	0.006
M21.6 Other acquired deformities of ankle and foot	0.000	0.994	0.006
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)	0.000	0.994	0.006
M22 Disorders of patella	0.000	0.994	0.006
L81.4 Other melanin hyperpigmentation	0.006	0.994	0.000
M21.85 Other specified acquired deformities of limbs (Pelvic region and thigh)	0.000	0.994	0.006
K57.5 Diverticular disease of both small and large intestine without perforation or abscess	0.006	0.994	0.000
R43.0 Anosmia	0.005	0.994	0.001
M22.8 Other disorders of patella	0.000	0.994	0.006
M21.89 Other specified acquired deformities of limbs (Site unspecified)	0.000	0.994	0.005
M21.88 Other specified acquired deformities of limbs-Other	0.000	0.994	0.005
M21.86 Other specified acquired deformities of limbs (Lower leg)	0.000	0.994	0.005
M21.84 Other specified acquired deformities of limbs (Hand)	0.000	0.994	0.005
M21.83 Other specified acquired deformities of limbs (Forearm)	0.000	0.994	0.005
M21.82 Other specified acquired deformities of limbs (Upper arm)	0.000	0.994	0.005
M21.81 Other specified acquired deformities of limbs (Shoulder region)	0.000	0.994	0.005
M21.80 Other specified acquired deformities of limbs (Multiple sites)	0.000	0.994	0.005
Z72.0 Tobacco use	0.006	0.994	0.000
M21.87 Other specified acquired deformities of limbs (Ankle and foot)	0.000	0.994	0.005
M21.47 Flat foot [pes planus] (acquired)-Ankle/foot	0.000	0.994	0.005
M21.73 Unequal limb length (acquired) (Forearm)	0.000	0.994	0.005
M21.22 Flexion deformity (Upper arm)	0.000	0.994	0.005
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.000	0.994	0.005
M21.49 Flat foot [pes planus] (acquired)-Site unspec	0.000	0.994	0.005
M21.48 Flat foot [pes planus] (acquired)-Other	0.000	0.994	0.005
M21.46 Flat foot [pes planus] (acquired)-Lower leg	0.000	0.994	0.005
M21.45 Flat foot [pes planus] (acquired)-Pelvic/thigh	0.000	0.994	0.005
M21.44 Flat foot [pes planus] (acquired)-Hand	0.000	0.994	0.005
M21.43 Flat foot [pes planus] (acquired)-Forearm	0.000	0.994	0.005
M21.42 Flat foot [pes planus] (acquired)-Upper arm	0.000	0.994	0.005
M21.41 Flat foot [pes planus] (acquired)-Shldr region	0.000	0.994	0.005
M21.40 Flat foot [pes planus] (acquired)-Mult sites	0.000	0.994	0.005
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.000	0.995	0.005
M22.9 Disorder of patella, unspecified	0.000	0.995	0.005
O72.1 Other immediate postpartum haemorrhage	0.000	0.995	0.005
M21.79 Unequal limb length (acquired) (Site unspecified)	0.000	0.995	0.005
M21.78 Unequal limb length (acquired)-Other	0.000	0.995	0.005
M21.77 Unequal limb length (acquired) (Ankle and foot)	0.000	0.995	0.005
M21.74 Unequal limb length (acquired) (Hand)	0.000	0.995	0.005
M21.72 Unequal limb length (acquired) (Upper arm)	0.000	0.995	0.005
M21.71 Unequal limb length (acquired)-Shldr region	0.000	0.995	0.005
M21.70 Unequal limb length (acquired) (Multiple sites)	0.000	0.995	0.005
M21.09 Valgus deformity, not elsewhere classified (Site unspecified)	0.000	0.995	0.005
M21.08 Valgus deformity, not elsewhere classified (Other)	0.000	0.995	0.005
M21.05 Valgus deformity, not elsewhere classified (Pelvic region and thigh)	0.000	0.995	0.005
M21.04 Valgus deformity, not elsewhere classified (Hand)	0.000	0.995	0.005
M21.03 Valgus deformity, not elsewhere classified (Forearm)	0.000	0.995	0.005
M21.02 Valgus deformity, not elsewhere classified (Upper arm)	0.000	0.995	0.005
M21.01 Valgus deformity, not elsewhere classified (Shoulder region)	0.000	0.995	0.005
M21.00 Valgus deformity, not elsewhere classified (Multiple sites)	0.000	0.995	0.005
M22.2 Patellofemoral disorders	0.000	0.995	0.005
K57.0 Diverticular disease of small intestine with perforation and abscess	0.005	0.995	0.000
M21.76 Unequal limb length (acquired) (Lower leg)	0.000	0.995	0.005
K57.2 Diverticular disease of large intestine with perforation and abscess	0.005	0.995	0.000
M21.75 Unequal limb length (acquired) (Pelvic region and thigh)	0.000	0.995	0.005
U80.1 Methicillin resistant agent	0.005	0.995	0.000
D35.2 Pituitary gland	0.000	0.995	0.005
I87.8 Other specified disorders of veins	0.005	0.995	0.000
M21.99 Acquired deformity of limb, unspecified (Site unspecified)	0.000	0.995	0.005
M21.98 Acquired deformity of limb, unspecified-Other	0.000	0.995	0.005
M21.96 Acquired deformity of limb, unspecified (Lower leg)	0.000	0.995	0.005
M21.95 Acquired deformity of limb, unspecified (Pelvic region and thigh)	0.000	0.995	0.005
M21.93 Acquired deformity of limb, unspecified (Forearm)	0.000	0.995	0.005
M21.92 Acquired deformity of limb, unspecified (Upper arm)	0.000	0.995	0.005
M21.91 Acquired deformity of limb, unspecified (Shoulder region)	0.000	0.995	0.005
M21.90 Acquired deformity of limb, unspecified (Multiple sites)	0.000	0.995	0.005
M21.69 Other acquired deformities of ankle and foot-Site unspec	0.000	0.995	0.005
M21.68 Other acquired deformities of ankle and foot-Other	0.000	0.995	0.005
M21.66 Other acquired deformities of ankle and foot-Lower leg	0.000	0.995	0.005
M21.65 Other acquired deformities of ankle and foot-Pelvic/thigh	0.000	0.995	0.005
M21.64 Other acquired deformities of ankle and foot-Hand	0.000	0.995	0.005
M21.63 Other acquired deformities of ankle and foot-Forearm	0.000	0.995	0.005
M21.62 Other acquired deformities of ankle and foot-Upper arm	0.000	0.995	0.005
M21.61 Other acquired deformities of ankle and foot-Shldr region	0.000	0.995	0.005
M21.60 Other acquired deformities of ankle and foot-Mult sites	0.000	0.995	0.005
M22.0 Recurrent dislocation of patella	0.000	0.995	0.005
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.000	0.995	0.005
R41.0 Disorientation, unspecified	0.005	0.995	0.000
G80 Infantile cerebral palsy	0.000	0.995	0.005
M21.94 Acquired deformity of limb, unspecified (Hand)	0.000	0.995	0.004
K57.4 Diverticular disease of both small and large intestine with perforation and abscess	0.004	0.995	0.000
R43.8 Other and unspecified disturbances of smell and taste	0.004	0.995	0.001
M22.1 Recurrent subluxation of patella	0.000	0.995	0.004
M21.97 Acquired deformity of limb, unspecified (Ankle and foot)	0.000	0.996	0.004
G80.2 Infantile hemiplegia	0.000	0.996	0.004
O43.1 Malformation of placenta	0.004	0.996	0.000
M21.59 Acquired clawhand, clubhand, clawfoot and clubfoot-Site uns	0.000	0.996	0.004
M21.58 Acquired clawhand, clubhand, clawfoot and clubfoot-Other	0.000	0.996	0.004
M21.56 Acquired clawhand, clubhand, clawfoot and clubfoot-Lower le	0.000	0.996	0.004
M21.55 Acquired clawhand, clubhand, clawfoot and clubfoot-Pelvic/t	0.000	0.996	0.004
M21.54 Acquired clawhand, clubhand, clawfoot and clubfoot (Hand)	0.000	0.996	0.004
M21.53 Acquired clawhand, clubhand, clawfoot and clubfoot-Forearm	0.000	0.996	0.004
M21.52 Acquired clawhand, clubhand, clawfoot and clubfoot-Upper ar	0.000	0.996	0.004
M21.51 Acquired clawhand, clubhand, clawfoot and clubfoot-Shldr re	0.000	0.996	0.004
M21.50 Acquired clawhand, clubhand, clawfoot and clubfoot (Multiple sites)	0.000	0.996	0.004
M22.3 Other derangements of patella	0.000	0.996	0.004
H50.1 Divergent concomitant strabismus	0.000	0.996	0.004
E55 Vitamin D deficiency	0.004	0.996	0.000
R73.9 Hyperglycaemia, unspecified	0.004	0.996	0.000
O63.0 Prolonged first stage (of labour)	0.000	0.996	0.004
G80.0 Spastic cerebral palsy	0.000	0.996	0.004
T79.3 Post-traumatic wound infection, not elsewhere classified	0.004	0.996	0.000
M21.67 Other acquired deformities of ankle and foot-Ankle/foot	0.000	0.996	0.004
C71.2 Temporal lobe	0.004	0.996	0.000
R16.0 Hepatomegaly, not elsewhere classified	0.004	0.996	0.000
H50.5 Heterophoria	0.000	0.996	0.004
M19.96 Arthrosis, unspecified-Lower leg	0.000	0.996	0.004
G80.1 Spastic diplegia	0.000	0.996	0.004
I87.2 Venous insufficiency (chronic) (peripheral)	0.004	0.996	0.000
T39.0 Salicylates	0.004	0.996	0.000
C71.0 Cerebrum, except lobes and ventricles	0.004	0.996	0.000
G80.4 Ataxic cerebral palsy	0.000	0.996	0.003
G80.3 Dyskinetic cerebral palsy	0.000	0.996	0.003
H01.0 Blepharitis	0.004	0.996	0.000
M87.20 Osteonecrosis due to previous trauma (Multiple sites)	0.000	0.996	0.004
G31.8 Other specified degenerative diseases of nervous system	0.004	0.996	0.000
M22.10 Recurrent subluxation of patella, unspecified knee	0.000	0.996	0.003
C71 Malignant neoplasm of brain	0.004	0.996	0.000
G80.8 Other infantile cerebral palsy	0.000	0.997	0.003
I87 Other disorders of veins	0.003	0.997	0.000
U80 Agent resistant to penicillin and related antibiotics	0.003	0.997	0.000
O43 Placental disorders	0.003	0.997	0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)	0.003	0.997	0.000
O43.0 Placental transfusion syndromes	0.003	0.997	0.000
L03.3 Cellulitis of trunk	0.003	0.997	0.000
H50 Other strabismus	0.000	0.997	0.003
I42.1 Obstructive hypertrophic cardiomyopathy	0.003	0.997	0.000
G51 Facial nerve disorders	0.000	0.997	0.003
C71.5 Cerebral ventricle	0.003	0.997	0.000
I42 Cardiomyopathy	0.003	0.997	0.000
E55.0 Rickets, active	0.003	0.997	0.000
H50.9 Strabismus, unspecified	0.000	0.997	0.003
I42.8 Other cardiomyopathies	0.003	0.997	0.000
O43.9 Placental disorder, unspecified	0.003	0.997	0.000
T78.1 Other adverse food reactions, not elsewhere classified	0.003	0.997	0.000
C09.9 Tonsil, unspecified	0.003	0.997	0.000
C71.9 Brain, unspecified	0.003	0.997	0.000
G60.0 Hereditary motor and sensory neuropathy	0.000	0.997	0.003
R42 Dizziness and giddiness	0.003	0.997	0.000
C71.8 Overlapping lesion of brain	0.003	0.997	0.000
I87.9 Disorder of vein, unspecified	0.003	0.997	0.000
N99.3 Prolapse of vaginal vault after hysterectomy	0.003	0.997	0.000
O43.8 Other placental disorders	0.003	0.997	0.000
R22.9 Localised swelling, mass and lump, unspecified	0.000	0.997	0.003
C71.7 Brain stem	0.003	0.997	0.000
C71.6 Cerebellum	0.003	0.997	0.000
I42.7 Cardiomyopathy due to drugs and other external agents	0.003	0.997	0.000
H50.6 Mechanical strabismus	0.000	0.997	0.003
U80.8 Agent resistant to other penicillin-related antibiotic	0.003	0.997	0.000
U80.0 Penicillin resistant agent	0.003	0.997	0.000
I87.0 Postphlebitic syndrome	0.003	0.997	0.000
G51.3 Clonic hemifacial spasm	0.000	0.997	0.003
O43.2 Morbidly adherent placenta	0.003	0.997	0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.000	0.997	0.003
C71.4 Occipital lobe	0.003	0.997	0.000
G51.9 Disorder of facial nerve, unspecified	0.000	0.997	0.003
H50.3 Intermittent heterotropia	0.000	0.997	0.003
G51.4 Facial myokymia	0.000	0.997	0.002
G51.2 Melkersson's syndrome	0.000	0.997	0.002
G51.1 Geniculate ganglionitis	0.000	0.997	0.002
O72 Postpartum haemorrhage	0.000	0.997	0.003
C71.3 Parietal lobe	0.003	0.997	0.000
I42.5 Other restrictive cardiomyopathy	0.002	0.997	0.000
I42.4 Endocardial fibroelastosis	0.002	0.997	0.000
I42.3 Endomyocardial (eosinophilic) disease	0.002	0.997	0.000
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)	0.001	0.997	0.002
H50.4 Other and unspecified heterotropia	0.000	0.997	0.002
H50.0 Convergent concomitant strabismus	0.000	0.997	0.003
F32 Depressive episode	0.003	0.997	0.000
M87.2 Osteonecrosis due to previous trauma	0.000	0.997	0.002
S90.9 Superficial injury of ankle and foot, unspecified	0.003	0.997	0.000
I87.1 Compression of vein	0.002	0.998	0.000
C71.1 Frontal lobe	0.002	0.998	0.000
I42.6 Alcoholic cardiomyopathy	0.002	0.998	0.000
G40.5 Special epileptic syndromes	0.002	0.998	0.000
H01 Other inflammation of eyelid	0.002	0.998	0.000
Q44.6 Cystic disease of liver	0.002	0.998	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.002	0.998	0.000
R80 Isolated proteinuria	0.002	0.998	0.000
M87.27 Osteonecrosis due to previous trauma (Ankle and foot)	0.000	0.998	0.002
H50.8 Other specified strabismus	0.000	0.998	0.002
G51.8 Other disorders of facial nerve	0.000	0.998	0.002
H01.8 Other specified inflammation of eyelid	0.002	0.998	0.000
O72.2 Delayed and secondary postpartum haemorrhage	0.000	0.998	0.002
O63 Long labour	0.000	0.998	0.002
M87.25 Osteonecrosis due to previous trauma (Pelvic region and thigh)	0.000	0.998	0.002
G61.8 Other inflammatory polyneuropathies	0.000	0.998	0.002
O63.9 Long labour, unspecified	0.000	0.998	0.002
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.002	0.998	0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.002	0.998	0.000
E04.9 Non-toxic goitre, unspecified	0.000	0.998	0.002
H01.9 Inflammation of eyelid, unspecified	0.002	0.998	0.000
L73.8 Other specified follicular disorders	0.002	0.998	0.000
T79 Certain early complications of trauma, not elsewhere classified	0.002	0.998	0.000
O72.3 Postpartum coagulation defects	0.000	0.998	0.002
T79.4 Traumatic shock	0.002	0.998	0.000
C18.0 Caecum	0.002	0.998	0.000
F32.8 Other depressive episodes	0.002	0.998	0.000
M87.29 Osteonecrosis due to previous trauma (Site unspecified)	0.000	0.998	0.002
M87.28 Osteonecrosis due to previous trauma (Other)	0.000	0.998	0.002
M87.26 Osteonecrosis due to previous trauma (Lower leg)	0.000	0.998	0.002
M87.24 Osteonecrosis due to previous trauma (Hand)	0.000	0.998	0.002
M87.23 Osteonecrosis due to previous trauma (Forearm)	0.000	0.998	0.002
M87.22 Osteonecrosis due to previous trauma (Upper arm)	0.000	0.998	0.002
M87.21 Osteonecrosis due to previous trauma (Shoulder region)	0.000	0.998	0.002
G60 Hereditary and idiopathic neuropathy	0.000	0.998	0.002
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)	0.000	0.998	0.002
F32.3 Severe depressive episode with psychotic symptoms	0.002	0.998	0.000
H01.1 Non-infectious dermatoses of eyelid	0.002	0.998	0.000
T40.4 Other synthetic narcotics	0.002	0.998	0.000
G61 Inflammatory polyneuropathy	0.000	0.998	0.002
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.002	0.998	0.000
H47.0 Disorders of optic nerve, not elsewhere classified	0.002	0.998	0.000
H50.2 Vertical strabismus	0.000	0.998	0.002
E04.2 Non-toxic multinodular goitre	0.000	0.998	0.002
Q87.4 Marfan's syndrome	0.002	0.998	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.002	0.998	0.000
C09 Malignant neoplasm of tonsil	0.002	0.998	0.000
T78 Adverse effects, not elsewhere classified	0.002	0.998	0.000
C09.0 Tonsillar fossa	0.002	0.998	0.000
D26.0 Cervix uteri	0.002	0.998	0.000
T42.3 Barbiturates	0.002	0.998	0.000
T78.4 Allergy, unspecified	0.002	0.998	0.000
L30.9 Dermatitis, unspecified	0.002	0.998	0.000
O63.2 Delayed delivery of second twin, triplet, etc.	0.000	0.998	0.002
G60.9 Hereditary and idiopathic neuropathy, unspecified	0.000	0.998	0.002
I42.2 Other hypertrophic cardiomyopathy	0.002	0.998	0.000
G61.0 Guillain-Barre syndrome	0.000	0.998	0.002
Q87.0 Congenital malformation syndromes predominantly affecting facial appearance	0.002	0.998	0.000
T39.4 Antirheumatics, not elsewhere classified	0.002	0.998	0.000
T39.2 Pyrazolone derivatives	0.002	0.998	0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.002	0.998	0.000
U89.8 Agent resistant to other single specified antibiotic	0.002	0.998	0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.002	0.998	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.002	0.998	0.000
F32.2 Severe depressive episode without psychotic symptoms	0.002	0.998	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.002	0.998	0.000
F32.0 Mild depressive episode	0.002	0.998	0.000
G61.9 Inflammatory polyneuropathy, unspecified	0.000	0.998	0.002
T40.5 Cocaine	0.002	0.998	0.000
T79.9 Unspecified early complication of trauma	0.002	0.998	0.000
T79.2 Traumatic secondary and recurrent haemorrhage	0.002	0.998	0.000
T79.1 Fat embolism (traumatic)	0.002	0.998	0.000
T79.0 Air embolism (traumatic)	0.002	0.998	0.000
G58.7 Mononeuritis multiplex	0.000	0.998	0.002
L30.8 Other specified dermatitis	0.002	0.998	0.000
Q87.1 Congenital malformation syndromes predominantly associated with short stature	0.002	0.998	0.000
T43.6 Psychostimulants with abuse potential	0.002	0.998	0.000
H25.1 Senile nuclear cataract	0.000	0.998	0.002
T83.0 Mechanical complication of urinary (indwelling) catheter	0.002	0.998	0.000
A04.7 Enterocolitis due to Clostridium difficile	0.000	0.998	0.002
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.002	0.998	0.000
T79.5 Traumatic anuria	0.002	0.998	0.000
H47.3 Other disorders of optic disk	0.002	0.998	0.000
G60.3 Idiopathic progressive neuropathy	0.000	0.998	0.002
G60.2 Neuropathy in association with hereditary ataxia	0.000	0.998	0.002
G60.1 Refsum's disease	0.000	0.998	0.002
T78.8 Other adverse effects, not elsewhere classified	0.002	0.998	0.000
T79.6 Traumatic ischaemia of muscle	0.002	0.998	0.000
G58.8 Other specified mononeuropathies	0.000	0.998	0.002
G61.1 Serum neuropathy	0.000	0.998	0.002
I77.9 Disorder of arteries and arterioles, unspecified	0.000	0.998	0.002
O62.0 Primary inadequate contractions	0.000	0.998	0.002
Q44.5 Other congenital malformations of bile ducts	0.002	0.998	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.002	0.998	0.000
T42.2 Succinimides and oxazolidinediones	0.002	0.998	0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.002	0.998	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.002	0.998	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.002	0.998	0.000
C09.8 Overlapping lesion of tonsil	0.002	0.998	0.000
O75.2 Pyrexia during labour, not elsewhere classified	0.000	0.998	0.002
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.002	0.998	0.000
T79.7 Traumatic subcutaneous emphysema	0.002	0.998	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.002	0.998	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
U89 Agent resistant to other and unspecified antibiotics	0.002	0.998	0.000
K57.1 Diverticular disease of small intestine without perforation or abscess	0.002	0.998	0.000
T40.1 Heroin	0.002	0.998	0.000
T78.2 Anaphylactic shock, unspecified	0.002	0.998	0.000
T78.9 Adverse effect, unspecified	0.002	0.998	0.000
T42.0 Hydantoin derivatives	0.002	0.998	0.000
X31.0 Home	0.002	0.998	0.000
T78.3 Angioneurotic oedema	0.002	0.998	0.000
C09.1 Tonsillar pillar (anterior) (posterior)	0.001	0.998	0.000
H47 Other disorders of optic [2nd] nerve and visual pathways	0.002	0.998	0.000
U50 Level of care administered to neonates	0.001	0.998	0.000
U07 Emergency use of U07	0.001	0.998	0.000
U06 Emergency use of U06	0.001	0.998	0.000
U04 Severe acute respiratory syndrome [SARS]	0.001	0.998	0.000
U52 First in a series of a regular day/night admissions	0.001	0.998	0.000
T02.40 Fractures involving multiple regions of both upper limbs (closed)	0.000	0.998	0.002
Q87.8 Other specified congenital malformation syndromes, not elsewhere classified	0.001	0.998	0.000
Q87.5 Other congenital malformation syndromes with other skeletal changes	0.001	0.998	0.000
Q87.3 Congenital malformation syndromes involving early overgrowth	0.001	0.998	0.000
Q87.2 Congenital malformation syndromes predominantly involving limbs	0.001	0.998	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.001	0.998	0.000
T40.8 Lysergide [LSD]	0.001	0.998	0.000
T40.7 Cannabis (derivatives)	0.001	0.998	0.000
T40.3 Methadone	0.001	0.998	0.000
T40.0 Opium	0.001	0.998	0.000
S52.80 Fracture of other parts of forearm (closed)	0.002	0.998	0.000
G30.0 Alzheimer's disease with early onset	0.002	0.998	0.000
N90.4 Leukoplakia of vulva	0.000	0.998	0.002
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.001	0.998	0.000
C64 Malignant neoplasm of kidney, except renal pelvis	0.000	0.998	0.002
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.001	0.998	0.000
G63.2 Diabetic polyneuropathy	0.000	0.998	0.002
N13.8 Other obstructive and reflux uropathy	0.002	0.998	0.000
N75.1 Abscess of Bartholin's gland	0.000	0.998	0.002
T43.5 Other and unspecified antipsychotics and neuroleptics	0.002	0.998	0.000
T47.0 Histamine H(2)-receptor antagonists	0.001	0.998	0.000
Z72.8 Other problems related to lifestyle	0.002	0.998	0.000
G31.2 Degeneration of nervous system due to alcohol	0.001	0.998	0.000
L30.3 Infective dermatitis	0.001	0.998	0.000
T42.4 Benzodiazepines	0.002	0.998	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.002	0.998	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.001	0.998	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.001	0.998	0.000
M81.90 Osteoporosis, unspecified (Multiple sites)	0.000	0.998	0.002
G82.2 Paraplegia, unspecified	0.001	0.998	0.000
N02.9 Unspecified	0.000	0.998	0.002
X51.9 Unspecified place	0.002	0.998	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.002	0.998	0.000
M24.51 Contracture of joint (Shoulder region)	0.002	0.998	0.000
G31.1 Senile degeneration of brain, not elsewhere classified	0.001	0.998	0.000
Q44.7 Other congenital malformations of liver	0.001	0.998	0.000
Q44.4 Choledochal cyst	0.001	0.998	0.000
Q44.3 Congenital stenosis and stricture of bile ducts	0.001	0.998	0.000
Q44.2 Atresia of bile ducts	0.001	0.998	0.000
Q44.1 Other congenital malformations of gallbladder	0.001	0.998	0.000
Q44.0 Agenesis, aplasia and hypoplasia of gallbladder	0.001	0.998	0.000
R23.4 Changes in skin texture	0.000	0.998	0.002
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.002	0.998	0.000
U89.9 Agent resistant to unspecified antibiotic	0.001	0.998	0.000
G63 Polyneuropathy in diseases classified elsewhere	0.000	0.998	0.001
T41 Poisoning by anaesthetics and therapeutic gases	0.001	0.998	0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.001	0.998	0.000
C04.9 Floor of mouth, unspecified	0.000	0.998	0.001
F60.3 Emotionally unstable personality disorder	0.001	0.998	0.000
O61.0 Failed medical induction of labour	0.000	0.998	0.001
Q54.9 Hypospadias, unspecified	0.001	0.998	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.001	0.998	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.001	0.998	0.000
G58 Other mononeuropathies	0.000	0.998	0.002
L30 Other dermatitis	0.002	0.998	0.000
H47.1 Papilloedema, unspecified	0.001	0.998	0.000
T43.9 Psychotropic drug, unspecified	0.001	0.998	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.001	0.998	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.001	0.998	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.001	0.998	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.001	0.998	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.001	0.998	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.001	0.998	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.001	0.998	0.000
T44.0 Anticholinesterase agents	0.001	0.998	0.000
T47.6 Antidiarrhoeal drugs	0.001	0.998	0.000
E04 Other non-toxic goitre	0.000	0.998	0.002
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.001	0.998	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.000	0.998	0.001
G83.8 Other specified paralytic syndromes	0.000	0.999	0.001
L81.7 Pigmented purpuric dermatosis	0.001	0.999	0.000
L81 Other disorders of pigmentation	0.001	0.999	0.000
G83.9 Paralytic syndrome, unspecified	0.000	0.999	0.001
S40.0 Contusion of shoulder and upper arm	0.001	0.999	0.000
S46.0 Injury of tendon of the rotator cuff of shoulder	0.001	0.999	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.001	0.999	0.000
T39.1 4-Aminophenol derivatives	0.001	0.999	0.000
T36 Poisoning by systemic antibiotics	0.001	0.999	0.000
S40.8 Other superficial injuries of shoulder and upper arm	0.001	0.999	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.001	0.999	0.000
T40.2 Other opioids	0.001	0.999	0.000
G83 Other paralytic syndromes	0.000	0.999	0.001
M66.47 Spontaneous rupture of other tendons (Ankle and foot)	0.001	0.999	0.000
G60.8 Other hereditary and idiopathic neuropathies	0.000	0.999	0.001
H47.7 Disorder of visual pathways, unspecified	0.001	0.999	0.000
H47.6 Disorders of visual cortex	0.001	0.999	0.000
H47.5 Disorders of other visual pathways	0.001	0.999	0.000
H47.4 Disorders of optic chiasm	0.001	0.999	0.000
J03.9 Acute tonsillitis, unspecified	0.001	0.999	0.000
N75.0 Cyst of Bartholin's gland	0.000	0.999	0.001
S00.1 Contusion of eyelid and periocular area	0.001	0.999	0.000
T79.8 Other early complications of trauma	0.001	0.999	0.000
U04.9 Severe acute respiratory syndrome [SARS], unspecified	0.001	0.999	0.000
U06.9 Emergency use of U06.9	0.001	0.999	0.000
U06.8 Emergency use of U06.8	0.001	0.999	0.000
U06.7 Emergency use of U06.7	0.001	0.999	0.000
U06.6 Emergency use of U06.6	0.001	0.999	0.000
U06.5 Emergency use of U06.5	0.001	0.999	0.000
U06.4 Emergency use of U06.4	0.001	0.999	0.000
U06.3 Emergency use of U06.3	0.001	0.999	0.000
U06.2 Emergency use of U06.2	0.001	0.999	0.000
U06.1 Emergency use of U06.1	0.001	0.999	0.000
U06.0 Emergency use of U06.0	0.001	0.999	0.000
U07.9 Emergency use of U07.9	0.001	0.999	0.000
U07.8 Emergency use of U07.8	0.001	0.999	0.000
U07.7 Emergency use of U07.7	0.001	0.999	0.000
U07.6 Emergency use of U07.6	0.001	0.999	0.000
U07.5 Emergency use of U07.5	0.001	0.999	0.000
U07.4 Emergency use of U07.4	0.001	0.999	0.000
U07.3 Emergency use of U07.3	0.001	0.999	0.000
U07.2 Emergency use of U07.2	0.001	0.999	0.000
U07.1 Emergency use of U07.1	0.001	0.999	0.000
U07.0 Emergency use of U07.0	0.001	0.999	0.000
U50.9 Inquest Adjourned Death	0.001	0.999	0.000
U50.3 Level of care administered to neonates (Maximal Intensive Care)	0.001	0.999	0.000
U50.2 Level of care administered to neonates (High Dependancy Intensive Care)	0.001	0.999	0.000
U50.1 Level of care administered to neonates (Special Care)	0.001	0.999	0.000
U50.0 Level of care administered to neonates (Normal Care)	0.001	0.999	0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.001	0.999	0.000
U88 Agent resistant to multiple antibiotics	0.001	0.999	0.000
B18.2 Chronic viral hepatitis C	0.000	0.999	0.001
G83.4 Cauda equina syndrome	0.000	0.999	0.001
O61.9 Failed induction of labour, unspecified	0.000	0.999	0.001
O72.0 Third-stage haemorrhage	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations