TreeWAS – Variant ID: rs9348862

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M45.X9 Ankylosing spondylitis (Site unspecified)	1.000	0.000	0.000
M06.9 Rheumatoid arthritis, unspecified	0.997	0.003	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.996	0.004	0.000
M06 Other rheumatoid arthritis	0.996	0.004	0.000
M45 Ankylosing spondylitis	0.995	0.005	0.000
M05-M14 Inflammatory polyarthropathies	0.984	0.016	0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.972	0.028	0.000
M06.0 Seronegative rheumatoid arthritis	0.965	0.035	0.000
E03.9 Hypothyroidism, unspecified	0.000	0.039	0.961
M07 Psoriatic and enteropathic arthropathies	0.957	0.043	0.000
E03 Other hypothyroidism	0.000	0.043	0.957
E10 Insulin-dependent diabetes mellitus	0.000	0.045	0.955
E00-E07 Disorders of thyroid gland	0.000	0.045	0.955
E10.9 Without complications	0.000	0.051	0.949
E10-E14 Diabetes mellitus	0.000	0.053	0.947
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.053	0.947
M07.3 Other psoriatic arthropathies	0.938	0.062	0.000
M45-M49 Spondylopathies	0.937	0.063	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.929	0.071	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.911	0.089	0.000
E10.1 With ketoacidosis	0.000	0.096	0.904
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.894	0.106	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.890	0.110	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.888	0.112	0.000
E10.3 With ophthalmic complications	0.000	0.134	0.866
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.147	0.853
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.844	0.156	0.000
M14 Arthropathies in other diseases classified elsewhere	0.834	0.166	0.000
E10.4 With neurological complications	0.000	0.177	0.823
M07.39 Other psoriatic arthropathies (Site unspecified)	0.821	0.179	0.000
E50-E64 Other nutritional deficiencies	0.000	0.189	0.811
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.795	0.205	0.000
E04 Other non-toxic goitre	0.000	0.208	0.792
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.790	0.210	0.000
E20-E35 Disorders of other endocrine glands	0.000	0.216	0.784
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.220	0.780
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.772	0.227	0.000
E10.5 With peripheral circulatory complications	0.000	0.228	0.772
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.771	0.229	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.771	0.229	0.000
M06.4 Inflammatory polyarthropathy	0.767	0.233	0.000
M05 Seropositive rheumatoid arthritis	0.765	0.235	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.758	0.242	0.000
M45.X2 Ankylosing spondylitis (Cervical region)	0.755	0.245	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.752	0.248	0.000
M06.3 Rheumatoid nodule	0.744	0.256	0.000
E55 Vitamin D deficiency	0.000	0.268	0.732
E13 Other specified diabetes mellitus	0.000	0.268	0.732
M00-M03 Infectious arthropathies	0.730	0.269	0.000
M14.6 Neuropathic arthropathy	0.726	0.274	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.715	0.285	0.000
M06.8 Other specified rheumatoid arthritis	0.714	0.286	0.000
M06.2 Rheumatoid bursitis	0.714	0.286	0.000
M06.1 Adult-onset Still's disease	0.714	0.286	0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.713	0.287	0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.713	0.287	0.000
M45.X6 Ankylosing spondylitis (Lumbar region)	0.713	0.287	0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.713	0.287	0.000
M45.X4 Ankylosing spondylitis (Thoracic region)	0.713	0.287	0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.713	0.287	0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.713	0.287	0.000
M80-M85 Disorders of bone density and structure	0.712	0.288	0.000
M12 Other specific arthropathies	0.706	0.294	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.706	0.294	0.000
M08 Juvenile arthritis	0.706	0.294	0.000
E40-E46 Malnutrition	0.000	0.299	0.701
E06 Thyroiditis	0.000	0.306	0.694
M86-M90 Other osteopathies	0.692	0.308	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.692	0.308	0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.692	0.308	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.692	0.308	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.692	0.308	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.692	0.308	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.692	0.308	0.000
E27 Other disorders of adrenal gland	0.000	0.313	0.687
M07.6 Other enteropathic arthropathies	0.686	0.314	0.000
M07.5 Arthropathy in ulcerative colitis	0.686	0.314	0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.686	0.314	0.000
M07.2 Psoriatic spondylitis	0.686	0.314	0.000
M07.1 Arthritis mutilans	0.686	0.314	0.000
M07.0 Distal interphalangeal psoriatic arthropathy	0.686	0.314	0.000
E04.1 Non-toxic single thyroid nodule	0.000	0.314	0.686
E03.5 Myxoedema coma	0.000	0.314	0.686
E03.4 Atrophy of thyroid (acquired)	0.000	0.314	0.686
E03.3 Postinfectious hypothyroidism	0.000	0.314	0.686
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.314	0.686
E03.1 Congenital hypothyroidism without goitre	0.000	0.314	0.686
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.314	0.686
E10.8 With unspecified complications	0.000	0.315	0.685
E10.7 With multiple complications	0.000	0.315	0.685
E10.0 With coma	0.000	0.315	0.685
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.315	0.685
E00 Congenital iodine-deficiency syndrome	0.000	0.315	0.685
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.315	0.685
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.320	0.680
M60-M63 Disorders of muscles	0.680	0.320	0.000
E12 Malnutrition-related diabetes mellitus	0.000	0.321	0.679
E07 Other disorders of thyroid	0.000	0.321	0.679
E55.9 Vitamin D deficiency, unspecified	0.000	0.325	0.675
M11 Other crystal arthropathies	0.675	0.325	0.000
M07.38 Other psoriatic arthropathies (Other)	0.672	0.327	0.000
M07.36 Other psoriatic arthropathies (Lower leg)	0.672	0.327	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.672	0.327	0.000
M07.34 Other psoriatic arthropathies (Hand)	0.672	0.327	0.000
M07.33 Other psoriatic arthropathies (Forearm)	0.672	0.327	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.672	0.327	0.000
M07.31 Other psoriatic arthropathies (Shoulder region)	0.672	0.327	0.000
M49 Spondylopathies in diseases classified elsewhere	0.672	0.328	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.338	0.662
E10.2 With renal complications	0.000	0.345	0.654
E05.9 Thyrotoxicosis, unspecified	0.000	0.348	0.652
M91-M94 Chondropathies	0.647	0.353	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.647	0.353	0.000
M40-M43 Deforming dorsopathies	0.647	0.353	0.000
E27.1 Primary adrenocortical insufficiency	0.000	0.354	0.646
E03.8 Other specified hypothyroidism	0.000	0.355	0.645
E22 Hyperfunction of pituitary gland	0.000	0.358	0.642
E04.2 Non-toxic multinodular goitre	0.000	0.360	0.640
M46 Other inflammatory spondylopathies	0.634	0.366	0.000
E05.8 Other thyrotoxicosis	0.000	0.388	0.611
E05.5 Thyroid crisis or storm	0.000	0.388	0.611
E05.4 Thyrotoxicosis factitia	0.000	0.388	0.611
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.388	0.611
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.388	0.611
M05.9 Seropositive rheumatoid arthritis, unspecified	0.608	0.392	0.000
E10.6 With other specified complications	0.000	0.393	0.607
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.606	0.394	0.000
E21.0 Primary hyperparathyroidism	0.000	0.398	0.602
M65-M68 Disorders of synovium and tendon	0.598	0.402	0.000
M80 Osteoporosis with pathological fracture	0.598	0.402	0.000
M14.8 Arthropathies in other specified diseases classified elsewhere	0.598	0.402	0.000
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders	0.598	0.402	0.000
M14.4 Arthropathy in amyloidosis	0.598	0.402	0.000
M14.3 Lipoid dermatoarthritis	0.598	0.402	0.000
M14.2 Diabetic arthropathy	0.598	0.402	0.000
M14.1 Crystal arthropathy in other metabolic disorders	0.598	0.402	0.000
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders	0.598	0.402	0.000
E04.0 Non-toxic diffuse goitre	0.000	0.405	0.595
E26 Hyperaldosteronism	0.000	0.407	0.593
M02 Reactive arthropathies	0.589	0.411	0.000
M85 Other disorders of bone density and structure	0.585	0.415	0.000
E14 Unspecified diabetes mellitus	0.000	0.416	0.584
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.418	0.582
E63 Other nutritional deficiencies	0.000	0.418	0.582
E56 Other vitamin deficiencies	0.000	0.418	0.582
E51 Thiamine deficiency	0.000	0.418	0.582
E50 Vitamin A deficiency	0.000	0.418	0.582
E60 Dietary zinc deficiency	0.000	0.418	0.582
E59 Dietary selenium deficiency	0.000	0.418	0.582
E58 Dietary calcium deficiency	0.000	0.418	0.582
E54 Ascorbic acid deficiency	0.000	0.418	0.582
E52 Niacin deficiency [pellagra]	0.000	0.418	0.582
M20-M25 Other joint disorders	0.580	0.420	0.000
E13.9 Without complications	0.000	0.422	0.577
E53 Deficiency of other B group vitamins	0.000	0.431	0.569
E04.8 Other specified non-toxic goitre	0.000	0.432	0.568
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.436	0.563
M06.34 Rheumatoid nodule (Hand)	0.563	0.437	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.438	0.562
E32 Diseases of thymus	0.000	0.438	0.562
E31 Polyglandular dysfunction	0.000	0.438	0.562
E30 Disorders of puberty, not elsewhere classified	0.000	0.438	0.562
E25 Adrenogenital disorders	0.000	0.438	0.562
E28 Ovarian dysfunction	0.000	0.439	0.561
M86 Osteomyelitis	0.553	0.446	0.000
E20 Hypoparathyroidism	0.000	0.449	0.551
M06.48 Inflammatory polyarthropathy (Other)	0.550	0.450	0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.550	0.450	0.000
M06.46 Inflammatory polyarthropathy (Lower leg)	0.550	0.450	0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.550	0.450	0.000
M06.44 Inflammatory polyarthropathy (Hand)	0.550	0.450	0.000
M06.43 Inflammatory polyarthropathy (Forearm)	0.550	0.450	0.000
M06.42 Inflammatory polyarthropathy (Upper arm)	0.550	0.450	0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.550	0.450	0.000
M05.8 Other seropositive rheumatoid arthritis	0.549	0.451	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.549	0.451	0.000
M05.2 Rheumatoid vasculitis	0.549	0.451	0.000
M05.1 Rheumatoid lung disease	0.549	0.451	0.000
M05.0 Felty's syndrome	0.549	0.451	0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.547	0.453	0.000
E61 Deficiency of other nutrient elements	0.000	0.454	0.546
M06.39 Rheumatoid nodule (Site unspecified)	0.533	0.467	0.000
M06.38 Rheumatoid nodule (Other)	0.533	0.467	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.533	0.467	0.000
M06.36 Rheumatoid nodule (Lower leg)	0.533	0.467	0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.533	0.467	0.000
M06.33 Rheumatoid nodule (Forearm)	0.533	0.467	0.000
M06.32 Rheumatoid nodule (Upper arm)	0.533	0.467	0.000
M06.31 Rheumatoid nodule (Shoulder region)	0.533	0.467	0.000
M06.30 Rheumatoid nodule (Multiple sites)	0.533	0.467	0.000
M24 Other specific joint derangements	0.526	0.474	0.000
E55.0 Rickets, active	0.000	0.475	0.525
E46 Unspecified protein-energy malnutrition	0.000	0.475	0.525
E13.8 With unspecified complications	0.000	0.475	0.525
E13.7 With multiple complications	0.000	0.475	0.525
E13.6 With other specified complications	0.000	0.475	0.525
E13.5 With peripheral circulatory complications	0.000	0.475	0.525
E13.4 With neurological complications	0.000	0.475	0.525
E13.3 With ophthalmic complications	0.000	0.475	0.525
E13.2 With renal complications	0.000	0.475	0.525
E13.1 With ketoacidosis	0.000	0.475	0.525
E13.0 With coma	0.000	0.475	0.525
M03 Postinfective and reactive arthropathies in diseases classified elsewhere	0.524	0.476	0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere	0.524	0.476	0.000
M00 Pyogenic arthritis	0.522	0.477	0.000
M89 Other disorders of bone	0.522	0.478	0.000
E06.9 Thyroiditis, unspecified	0.000	0.483	0.517
M34 Systemic sclerosis	0.516	0.484	0.000
M40 Kyphosis and lordosis	0.516	0.484	0.000
M10 Gout	0.514	0.486	0.000
E22.0 Acromegaly and pituitary gigantism	0.000	0.488	0.512
M06.19 Adult-onset Still's disease (Site unspecified)	0.512	0.488	0.000
M06.18 Adult-onset Still's disease (Other)	0.512	0.488	0.000
M06.17 Adult-onset Still's disease (Ankle and foot)	0.512	0.488	0.000
M06.16 Adult-onset Still's disease (Lower leg)	0.512	0.488	0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.512	0.488	0.000
M06.14 Adult-onset Still's disease (Hand)	0.512	0.488	0.000
M06.13 Adult-onset Still's disease (Forearm)	0.512	0.488	0.000
M06.12 Adult-onset Still's disease (Upper arm)	0.512	0.488	0.000
M06.11 Adult-onset Still's disease (Shoulder region)	0.512	0.488	0.000
M06.10 Adult-onset Still's disease (Multiple sites)	0.512	0.488	0.000
M06.29 Rheumatoid bursitis (Site unspecified)	0.512	0.488	0.000
M06.28 Rheumatoid bursitis (Other)	0.512	0.488	0.000
M06.27 Rheumatoid bursitis (Ankle and foot)	0.512	0.488	0.000
M06.26 Rheumatoid bursitis (Lower leg)	0.512	0.488	0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.512	0.488	0.000
M06.24 Rheumatoid bursitis (Hand)	0.512	0.488	0.000
M06.23 Rheumatoid bursitis (Forearm)	0.512	0.488	0.000
M06.22 Rheumatoid bursitis (Upper arm)	0.512	0.488	0.000
M06.21 Rheumatoid bursitis (Shoulder region)	0.512	0.488	0.000
M06.20 Rheumatoid bursitis (Multiple sites)	0.512	0.488	0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.512	0.488	0.000
M06.88 Other specified rheumatoid arthritis (Other)	0.512	0.488	0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.512	0.488	0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.512	0.488	0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.512	0.488	0.000
M06.84 Other specified rheumatoid arthritis (Hand)	0.512	0.488	0.000
M06.83 Other specified rheumatoid arthritis (Forearm)	0.512	0.488	0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.512	0.488	0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.512	0.488	0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.512	0.488	0.000
M83 Adult osteomalacia	0.510	0.490	0.000
M82 Osteoporosis in diseases classified elsewhere	0.510	0.490	0.000
E24 Cushing's syndrome	0.000	0.490	0.510
E34 Other endocrine disorders	0.000	0.493	0.507
M08.9 Juvenile arthritis, unspecified	0.506	0.494	0.000
M08.8 Other juvenile arthritis	0.506	0.494	0.000
M08.4 Pauciarticular juvenile arthritis	0.506	0.494	0.000
M08.3 Juvenile polyarthritis (seronegative)	0.506	0.494	0.000
M08.2 Juvenile arthritis with systemic onset	0.506	0.494	0.000
M08.1 Juvenile ankylosing spondylitis	0.506	0.494	0.000
M08.0 Juvenile rheumatoid arthritis	0.506	0.494	0.000
M09.8 Juvenile arthritis in other diseases classified elsewhere	0.506	0.494	0.000
M09.2 Juvenile arthritis in ulcerative colitis	0.506	0.494	0.000
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]	0.506	0.494	0.000
M09.0 Juvenile arthritis in psoriasis	0.506	0.494	0.000
M12.8 Other specific arthropathies, not elsewhere classified	0.506	0.494	0.000
M12.5 Traumatic arthropathy	0.506	0.494	0.000
M12.4 Intermittent hydrarthrosis	0.506	0.494	0.000
M12.3 Palindromic rheumatism	0.506	0.494	0.000
M12.2 Villonodular synovitis (pigmented)	0.506	0.494	0.000
M12.1 Kaschin-Beck disease	0.506	0.494	0.000
M12.0 Chronic postrheumatic arthropathy [Jaccoud]	0.506	0.494	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.497	0.502
E45 Retarded development following protein-energy malnutrition	0.000	0.497	0.502
E43 Unspecified severe protein-energy malnutrition	0.000	0.497	0.502
E42 Marasmic kwashiorkor	0.000	0.497	0.502
E41 Nutritional marasmus	0.000	0.497	0.502
E40 Kwashiorkor	0.000	0.497	0.502
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.502	0.498	0.000
E07.9 Disorder of thyroid, unspecified	0.000	0.498	0.502
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.502	0.498	0.000
M62 Other disorders of muscle	0.501	0.499	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.500	0.500
M92 Other juvenile osteochondrosis	0.500	0.500	0.000
E06.5 Other chronic thyroiditis	0.000	0.502	0.498
E06.4 Drug-induced thyroiditis	0.000	0.502	0.498
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.502	0.498
E06.1 Subacute thyroiditis	0.000	0.502	0.498
E06.0 Acute thyroiditis	0.000	0.502	0.498
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.493	0.507	0.000
E27.5 Adrenomedullary hyperfunction	0.000	0.507	0.492
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.507	0.492
E27.2 Addisonian crisis	0.000	0.507	0.492
E27.0 Other adrenocortical overactivity	0.000	0.507	0.492
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)	0.492	0.508	0.000
M07.08 Distal interphalangeal proriatic arthropathy-Other	0.492	0.508	0.000
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)	0.492	0.508	0.000
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg	0.492	0.508	0.000
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh	0.492	0.508	0.000
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)	0.492	0.508	0.000
M07.03 Distal interphalangeal proriatic arthropathy-Forearm	0.492	0.508	0.000
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm	0.492	0.508	0.000
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region	0.492	0.508	0.000
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)	0.492	0.508	0.000
M07.19 Arthritis mutilans (Site unspecified)	0.492	0.508	0.000
M07.18 Arthritis mutilans (Other)	0.492	0.508	0.000
M07.17 Arthritis mutilans (Ankle and foot)	0.492	0.508	0.000
M07.16 Arthritis mutilans (Lower leg)	0.492	0.508	0.000
M07.15 Arthritis mutilans (Pelvic region and thigh)	0.492	0.508	0.000
M07.14 Arthritis mutilans (Hand)	0.492	0.508	0.000
M07.13 Arthritis mutilans (Forearm)	0.492	0.508	0.000
M07.12 Arthritis mutilans (Upper arm)	0.492	0.508	0.000
M07.11 Arthritis mutilans (Shoulder region)	0.492	0.508	0.000
M07.10 Arthritis mutilans (Multiple sites)	0.492	0.508	0.000
M07.29 Psoriatic spondylitis (Site unspecified)	0.492	0.508	0.000
M07.28 Psoriatic spondylitis (Other)	0.492	0.508	0.000
M07.27 Psoriatic spondylitis (Ankle and foot)	0.492	0.508	0.000
M07.26 Psoriatic spondylitis (Lower leg)	0.492	0.508	0.000
M07.25 Psoriatic spondylitis (Pelvic region and thigh)	0.492	0.508	0.000
M07.24 Psoriatic spondylitis (Hand)	0.492	0.508	0.000
M07.23 Psoriatic spondylitis (Forearm)	0.492	0.508	0.000
M07.22 Psoriatic spondylitis (Upper arm)	0.492	0.508	0.000
M07.21 Psoriatic spondylitis (Shoulder region)	0.492	0.508	0.000
M07.20 Psoriatic spondylitis (Multiple sites)	0.492	0.508	0.000
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)	0.492	0.508	0.000
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)	0.492	0.508	0.000
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)	0.492	0.508	0.000
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)	0.492	0.508	0.000
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)	0.492	0.508	0.000
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)	0.492	0.508	0.000
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)	0.492	0.508	0.000
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)	0.492	0.508	0.000
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)	0.492	0.508	0.000
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)	0.492	0.508	0.000
M07.59 Arthropathy in ulcerative colitis (Site unspecified)	0.492	0.508	0.000
M07.58 Arthropathy in ulcerative colitis (Other)	0.492	0.508	0.000
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)	0.492	0.508	0.000
M07.56 Arthropathy in ulcerative colitis (Lower leg)	0.492	0.508	0.000
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)	0.492	0.508	0.000
M07.54 Arthropathy in ulcerative colitis (Hand)	0.492	0.508	0.000
M07.53 Arthropathy in ulcerative colitis (Forearm)	0.492	0.508	0.000
M07.52 Arthropathy in ulcerative colitis (Upper arm)	0.492	0.508	0.000
M07.51 Arthropathy in ulcerative colitis (Shoulder region)	0.492	0.508	0.000
M07.50 Arthropathy in ulcerative colitis (Multiple sites)	0.492	0.508	0.000
M07.69 Other enteropathic arthropathies (Site unspecified)	0.492	0.508	0.000
M07.68 Other enteropathic arthropathies (Other)	0.492	0.508	0.000
M07.67 Other enteropathic arthropathies (Ankle and foot)	0.492	0.508	0.000
M07.66 Other enteropathic arthropathies (Lower leg)	0.492	0.508	0.000
M07.65 Other enteropathic arthropathies (Pelvic region and thigh)	0.492	0.508	0.000
M07.64 Other enteropathic arthropathies (Hand)	0.492	0.508	0.000
M07.63 Other enteropathic arthropathies (Forearm)	0.492	0.508	0.000
M07.62 Other enteropathic arthropathies (Upper arm)	0.492	0.508	0.000
M07.61 Other enteropathic arthropathies (Shoulder region)	0.492	0.508	0.000
M07.60 Other enteropathic arthropathies (Multiple sites)	0.492	0.508	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.509	0.491
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.509	0.491
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.509	0.491
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.509	0.491
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.509	0.491
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.509	0.491
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.509	0.491
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.509	0.491
E16 Other disorders of pancreatic internal secretion	0.000	0.510	0.490
E15 Nondiabetic hypoglycaemic coma	0.000	0.512	0.488
M63 Disorders of muscle in diseases classified elsewhere	0.487	0.512	0.000
M61 Calcification and ossification of muscle	0.487	0.512	0.000
M60 Myositis	0.487	0.512	0.000
M02.3 Reiter's disease	0.487	0.513	0.000
E06.3 Autoimmune thyroiditis	0.000	0.513	0.487
E12.9 Without complications	0.000	0.513	0.487
E12.8 With unspecified complications	0.000	0.513	0.487
E12.7 With multiple complications	0.000	0.513	0.487
E12.6 With other specified complications	0.000	0.513	0.487
E12.5 With peripheral circulatory complications	0.000	0.513	0.487
E12.4 With neurological complications	0.000	0.513	0.487
E12.3 With ophthalmic complications	0.000	0.513	0.487
E12.2 With renal complications	0.000	0.513	0.487
E12.1 With ketoacidosis	0.000	0.513	0.487
E12.0 With coma	0.000	0.513	0.487
E07.1 Dyshormogenetic goitre	0.000	0.513	0.486
E07.0 Hypersecretion of calcitonin	0.000	0.513	0.486
M90 Osteopathies in diseases classified elsewhere	0.485	0.515	0.000
M11.9 Crystal arthropathy, unspecified	0.484	0.516	0.000
M11.8 Other specified crystal arthropathies	0.484	0.516	0.000
M11.1 Familial chondrocalcinosis	0.484	0.516	0.000
M11.0 Hydroxyapatite deposition disease	0.484	0.516	0.000
M49.8 Spondylopathy in other diseases classified elsewhere	0.482	0.518	0.000
M49.5 Collapsed vertebra in diseases classified elsewhere	0.482	0.518	0.000
M49.4 Neuropathic spondylopathy	0.482	0.518	0.000
M49.3 Spondylopathy in other infectious and parasitic diseases classified elsewhere	0.482	0.518	0.000
M49.2 Enterobacterial spondylitis	0.482	0.518	0.000
M49.1 Brucella spondylitis	0.482	0.518	0.000
M49.0 Tuberculosis of spine	0.482	0.518	0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.480	0.520	0.000
M85.0 Fibrous dysplasia (monostotic)	0.479	0.520	0.000
M88 Paget's disease of bone [osteitis deformans]	0.477	0.523	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.000	0.525	0.475
E21.4 Other specified disorders of parathyroid gland	0.000	0.525	0.475
E21.2 Other hyperparathyroidism	0.000	0.525	0.475
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.000	0.525	0.475
M34.9 Systemic sclerosis, unspecified	0.467	0.532	0.000
M80.0 Postmenopausal osteoporosis with pathological fracture	0.467	0.533	0.000
M85.6 Other cyst of bone	0.467	0.533	0.000
M21 Other acquired deformities of limbs	0.466	0.534	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.535	0.465
M91 Juvenile osteochondrosis of hip and pelvis	0.464	0.536	0.000
M42 Spinal osteochondrosis	0.464	0.536	0.000
E07.8 Other specified disorders of thyroid	0.000	0.537	0.463
E27.8 Other specified disorders of adrenal gland	0.000	0.539	0.461
M67 Other disorders of synovium and tendon	0.461	0.539	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.539	0.460
E22.8 Other hyperfunction of pituitary gland	0.000	0.539	0.460
E22.1 Hyperprolactinaemia	0.000	0.539	0.460
M31 Other necrotising vasculopathies	0.459	0.541	0.000
M84 Disorders of continuity of bone	0.459	0.541	0.000
M46.4 Discitis, unspecified	0.457	0.543	0.000
E26.0 Primary hyperaldosteronism	0.000	0.544	0.456
M46.8 Other specified inflammatory spondylopathies	0.455	0.545	0.000
M46.5 Other infective spondylopathies	0.455	0.545	0.000
M46.3 Infection of intervertebral disk (pyogenic)	0.455	0.545	0.000
M46.2 Osteomyelitis of vertebra	0.455	0.545	0.000
M46.1 Sacro-iliitis, not elsewhere classified	0.455	0.545	0.000
M46.0 Spinal enthesopathy	0.455	0.545	0.000
E29 Testicular dysfunction	0.000	0.545	0.454
M11.2 Other chondrocalcinosis	0.453	0.547	0.000
M87 Osteonecrosis	0.452	0.548	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.447	0.553	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.447	0.553	0.000
M23 Internal derangement of knee	0.441	0.559	0.000
M94 Other disorders of cartilage	0.439	0.561	0.000
M48 Other spondylopathies	0.438	0.562	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.437	0.563	0.000
E27.9 Disorder of adrenal gland, unspecified	0.000	0.563	0.436
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.436	0.564	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.436	0.564	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.436	0.564	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.436	0.564	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.436	0.564	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.436	0.564	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.436	0.564	0.000
M13 Other arthritis	0.434	0.566	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.430	0.570	0.000
M86.9 Osteomyelitis, unspecified	0.429	0.570	0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.429	0.571	0.000
M80.8 Other osteoporosis with pathological fracture	0.429	0.571	0.000
M80.5 Idiopathic osteoporosis with pathological fracture	0.429	0.571	0.000
M80.4 Drug-induced osteoporosis with pathological fracture	0.429	0.571	0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.429	0.571	0.000
M80.2 Osteoporosis of disuse with pathological fracture	0.429	0.571	0.000
M86.6 Other chronic osteomyelitis	0.428	0.572	0.000
M93 Other osteochondropathies	0.427	0.573	0.000
M31.3 Wegener's granulomatosis	0.427	0.573	0.000
E70-E90 Metabolic disorders	0.000	0.574	0.426
E26.9 Hyperaldosteronism, unspecified	0.000	0.575	0.425
E26.8 Other hyperaldosteronism	0.000	0.575	0.425
E26.1 Secondary hyperaldosteronism	0.000	0.575	0.425
M24.0 Loose body in joint	0.424	0.575	0.000
M50-M54 Other dorsopathies	0.424	0.576	0.000
M02.9 Reactive arthopathy, unspecified	0.422	0.578	0.000
M02.8 Other reactive arthropathies	0.422	0.578	0.000
M02.2 Postimmunisation arthropathy	0.422	0.578	0.000
M02.1 Postdysenteric arthropathy	0.422	0.578	0.000
M02.0 Arthropathy following intestinal bypass	0.422	0.578	0.000
M43 Other deforming dorsopathies	0.422	0.578	0.000
M40.2 Other and unspecified kyphosis	0.421	0.578	0.000
M85.9 Disorder of bone density and structure, unspecified	0.419	0.581	0.000
M85.5 Aneurysmal bone cyst	0.419	0.581	0.000
M85.4 Solitary bone cyst	0.419	0.581	0.000
M85.3 Osteitis condensans	0.419	0.581	0.000
M85.2 Hyperostosis of skull	0.419	0.581	0.000
M85.1 Skeletal fluorosis	0.419	0.581	0.000
E14.8 With unspecified complications	0.000	0.581	0.419
E14.7 With multiple complications	0.000	0.581	0.419
E14.6 With other specified complications	0.000	0.581	0.419
E14.5 With peripheral circulatory complications	0.000	0.581	0.419
E14.4 With neurological complications	0.000	0.581	0.419
E14.2 Withrenal complications	0.000	0.581	0.419
E14.1 With ketoacidosis	0.000	0.581	0.419
E14.0 With coma	0.000	0.581	0.419
M41 Scoliosis	0.418	0.582	0.000
E50.9 Vitamin A deficiency, unspecified	0.000	0.583	0.417
E50.8 Other manifestations of vitamin A deficiency	0.000	0.583	0.417
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.583	0.417
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.583	0.417
E50.5 Vitamin A deficiency with night blindness	0.000	0.583	0.417
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.583	0.417
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.583	0.417
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.583	0.417
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.583	0.417
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.583	0.417
E51.9 Thiamine deficiency, unspecified	0.000	0.583	0.417
E51.8 Other manifestations of thiamine deficiency	0.000	0.583	0.417
E51.2 Wernicke's encephalopathy	0.000	0.583	0.417
E51.1 Beriberi	0.000	0.583	0.417
E56.9 Vitamin deficiency, unspecified	0.000	0.583	0.417
E56.8 Deficiency of other vitamins	0.000	0.583	0.417
E56.1 Deficiency of vitamin K	0.000	0.583	0.417
E56.0 Deficiency of vitamin E	0.000	0.583	0.417
E63.9 Nutritional deficiency, unspecified	0.000	0.583	0.417
E63.8 Other specified nutritional deficiencies	0.000	0.583	0.417
E63.1 Imbalance of constituents of food intake	0.000	0.583	0.417
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.583	0.417
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.583	0.417
E64.8 Sequelae of other nutritional deficiencies	0.000	0.583	0.417
E64.3 Sequelae of rickets	0.000	0.583	0.417
E64.2 Sequelae of vitamin C deficiency	0.000	0.583	0.417
E64.1 Sequelae of vitamin A deficiency	0.000	0.583	0.417
E64.0 Sequelae of protein-energy malnutrition	0.000	0.583	0.417
E65-E68 Obesity and other hyperalimentation	0.000	0.583	0.417

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations