TreeWAS – Variant ID: rs9348863

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M45.X9 Ankylosing spondylitis (Site unspecified)	1.000	0.000	0.000
E03.9 Hypothyroidism, unspecified	0.000	0.000	1.000
E00-E07 Disorders of thyroid gland	0.000	0.001	0.999
M06.9 Rheumatoid arthritis, unspecified	0.999	0.001	0.000
E03 Other hypothyroidism	0.000	0.001	0.999
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.999	0.001	0.000
E10 Insulin-dependent diabetes mellitus	0.000	0.001	0.999
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.001	0.999
E10-E14 Diabetes mellitus	0.000	0.002	0.998
M06 Other rheumatoid arthritis	0.998	0.002	0.000
M45 Ankylosing spondylitis	0.996	0.004	0.000
M05-M14 Inflammatory polyarthropathies	0.992	0.008	0.000
E10.9 Without complications	0.000	0.009	0.991
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.973	0.027	0.000
M07 Psoriatic and enteropathic arthropathies	0.968	0.032	0.000
E10.1 With ketoacidosis	0.000	0.035	0.965
M45-M49 Spondylopathies	0.954	0.046	0.000
M07.3 Other psoriatic arthropathies	0.951	0.049	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.949	0.051	0.000
E10.3 With ophthalmic complications	0.000	0.058	0.942
M06.0 Seronegative rheumatoid arthritis	0.929	0.071	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.085	0.915
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.903	0.097	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.900	0.100	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.887	0.113	0.000
E50-E64 Other nutritional deficiencies	0.000	0.114	0.886
E70-E90 Metabolic disorders	0.000	0.123	0.877
E10.4 With neurological complications	0.000	0.124	0.876
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.871	0.129	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.856	0.144	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.849	0.151	0.000
E04 Other non-toxic goitre	0.000	0.152	0.848
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.157	0.843
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.829	0.171	0.000
E10.5 With peripheral circulatory complications	0.000	0.173	0.827
K90.0 Coeliac disease	0.000	0.175	0.825
M05 Seropositive rheumatoid arthritis	0.824	0.176	0.000
E55 Vitamin D deficiency	0.000	0.187	0.813
E06 Thyroiditis	0.000	0.191	0.809
M14 Arthropathies in other diseases classified elsewhere	0.796	0.203	0.000
E87 Other disorders of fluid, electrolyte and acid-base balance	0.000	0.204	0.796
M06.4 Inflammatory polyarthropathy	0.788	0.212	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.788	0.212	0.000
E13 Other specified diabetes mellitus	0.000	0.216	0.784
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.218	0.782
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.781	0.219	0.000
M80-M85 Disorders of bone density and structure	0.778	0.222	0.000
E87.6 Hypokalaemia	0.000	0.226	0.774
E55.9 Vitamin D deficiency, unspecified	0.000	0.239	0.761
E20-E35 Disorders of other endocrine glands	0.000	0.241	0.759
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.752	0.247	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.752	0.248	0.000
M45.X2 Ankylosing spondylitis (Cervical region)	0.751	0.249	0.000
M06.3 Rheumatoid nodule	0.743	0.257	0.000
M00-M03 Infectious arthropathies	0.742	0.258	0.000
E04.2 Non-toxic multinodular goitre	0.000	0.267	0.733
E88 Other metabolic disorders	0.000	0.271	0.728
E40-E46 Malnutrition	0.000	0.279	0.721
M40-M43 Deforming dorsopathies	0.718	0.282	0.000
M60-M63 Disorders of muscles	0.717	0.283	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.000	0.283	0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.283	0.717
E00 Congenital iodine-deficiency syndrome	0.000	0.283	0.717
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.283	0.717
M06.98 Rheumatoid arthritis, unspecified (Other)	0.716	0.283	0.000
E03.5 Myxoedema coma	0.000	0.283	0.716
E03.4 Atrophy of thyroid (acquired)	0.000	0.283	0.716
E03.3 Postinfectious hypothyroidism	0.000	0.283	0.716
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.283	0.716
E03.1 Congenital hypothyroidism without goitre	0.000	0.283	0.716
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.283	0.716
E10.8 With unspecified complications	0.000	0.284	0.716
E10.7 With multiple complications	0.000	0.284	0.716
E10.0 With coma	0.000	0.284	0.716
E12 Malnutrition-related diabetes mellitus	0.000	0.284	0.716
M06.8 Other specified rheumatoid arthritis	0.715	0.284	0.000
M06.2 Rheumatoid bursitis	0.715	0.284	0.000
M06.1 Adult-onset Still's disease	0.715	0.284	0.000
E14 Unspecified diabetes mellitus	0.000	0.285	0.715
E07 Other disorders of thyroid	0.000	0.286	0.714
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.714	0.286	0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.714	0.286	0.000
M45.X6 Ankylosing spondylitis (Lumbar region)	0.714	0.286	0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.714	0.286	0.000
M45.X4 Ankylosing spondylitis (Thoracic region)	0.714	0.286	0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.714	0.286	0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.714	0.286	0.000
M12 Other specific arthropathies	0.711	0.289	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.711	0.289	0.000
M08 Juvenile arthritis	0.711	0.289	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.704	0.296	0.000
E04.1 Non-toxic single thyroid nodule	0.000	0.298	0.702
E05.9 Thyrotoxicosis, unspecified	0.000	0.302	0.698
E10.2 With renal complications	0.000	0.303	0.697
M07.6 Other enteropathic arthropathies	0.694	0.306	0.000
M07.5 Arthropathy in ulcerative colitis	0.694	0.306	0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.694	0.306	0.000
M07.2 Psoriatic spondylitis	0.694	0.306	0.000
M07.1 Arthritis mutilans	0.694	0.306	0.000
M07.0 Distal interphalangeal psoriatic arthropathy	0.694	0.306	0.000
M80 Osteoporosis with pathological fracture	0.690	0.310	0.000
E73 Lactose intolerance	0.000	0.316	0.684
M07.38 Other psoriatic arthropathies (Other)	0.682	0.318	0.000
M07.36 Other psoriatic arthropathies (Lower leg)	0.682	0.318	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.682	0.318	0.000
M07.34 Other psoriatic arthropathies (Hand)	0.682	0.318	0.000
M07.33 Other psoriatic arthropathies (Forearm)	0.682	0.318	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.682	0.318	0.000
M07.31 Other psoriatic arthropathies (Shoulder region)	0.682	0.318	0.000
M11 Other crystal arthropathies	0.681	0.318	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.678	0.322	0.000
M49 Spondylopathies in diseases classified elsewhere	0.672	0.328	0.000
M91-M94 Chondropathies	0.671	0.329	0.000
E87.0 Hyperosmolality and hypernatraemia	0.000	0.332	0.668
M06.08 Seronegative rheumatoid arthritis (Other)	0.666	0.334	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.666	0.334	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.666	0.334	0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.666	0.334	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.666	0.334	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.666	0.334	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.666	0.334	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.666	0.334	0.000
E86 Volume depletion	0.000	0.335	0.665
E03.8 Other specified hypothyroidism	0.000	0.335	0.664
E83 Disorders of mineral metabolism	0.000	0.341	0.659
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.342	0.658
M14.6 Neuropathic arthropathy	0.657	0.343	0.000
E05.8 Other thyrotoxicosis	0.000	0.344	0.656
E05.5 Thyroid crisis or storm	0.000	0.344	0.656
E05.4 Thyrotoxicosis factitia	0.000	0.344	0.656
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.344	0.656
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.344	0.656
M86-M90 Other osteopathies	0.656	0.344	0.000
E06.3 Autoimmune thyroiditis	0.000	0.344	0.656
M85 Other disorders of bone density and structure	0.644	0.355	0.000
E87.1 Hypo-osmolality and hyponatraemia	0.000	0.360	0.640
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.362	0.638
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.637	0.363	0.000
E53 Deficiency of other B group vitamins	0.000	0.363	0.637
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.365	0.635
E63 Other nutritional deficiencies	0.000	0.365	0.635
E56 Other vitamin deficiencies	0.000	0.365	0.635
E51 Thiamine deficiency	0.000	0.365	0.635
E50 Vitamin A deficiency	0.000	0.365	0.635
E60 Dietary zinc deficiency	0.000	0.365	0.635
E59 Dietary selenium deficiency	0.000	0.365	0.635
E58 Dietary calcium deficiency	0.000	0.365	0.635
E54 Ascorbic acid deficiency	0.000	0.365	0.635
E52 Niacin deficiency [pellagra]	0.000	0.365	0.635
E10.6 With other specified complications	0.000	0.368	0.632
E13.9 Without complications	0.000	0.369	0.631
E27 Other disorders of adrenal gland	0.000	0.371	0.629
E85 Amyloidosis	0.000	0.371	0.628
E84 Cystic fibrosis	0.000	0.371	0.628
E79 Disorders of purine and pyrimidine metabolism	0.000	0.371	0.628
E77 Disorders of glycoprotein metabolism	0.000	0.371	0.628
E76 Disorders of glycosaminoglycan metabolism	0.000	0.371	0.628
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.000	0.371	0.628
E72 Other disorders of amino-acid metabolism	0.000	0.371	0.628
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.000	0.371	0.628
E70 Disorders of aromatic amino-acid metabolism	0.000	0.371	0.628
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.000	0.371	0.628
E16 Other disorders of pancreatic internal secretion	0.000	0.373	0.627
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.000	0.378	0.622
E22 Hyperfunction of pituitary gland	0.000	0.380	0.620
E74 Other disorders of carbohydrate metabolism	0.000	0.381	0.619
E04.0 Non-toxic diffuse goitre	0.000	0.384	0.616
E04.8 Other specified non-toxic goitre	0.000	0.392	0.608
E61 Deficiency of other nutrient elements	0.000	0.392	0.608
M02 Reactive arthropathies	0.608	0.392	0.000
E06.9 Thyroiditis, unspecified	0.000	0.396	0.604
M46 Other inflammatory spondylopathies	0.603	0.397	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.599	0.401	0.000
E87.5 Hyperkalaemia	0.000	0.404	0.596
M80.9 Unspecified osteoporosis with pathological fracture	0.594	0.406	0.000
M05.8 Other seropositive rheumatoid arthritis	0.591	0.409	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.591	0.409	0.000
M05.2 Rheumatoid vasculitis	0.591	0.409	0.000
M05.1 Rheumatoid lung disease	0.591	0.409	0.000
M05.0 Felty's syndrome	0.591	0.409	0.000
M50-M54 Other dorsopathies	0.585	0.415	0.000
E55.0 Rickets, active	0.000	0.417	0.583
E06.5 Other chronic thyroiditis	0.000	0.420	0.580
E06.4 Drug-induced thyroiditis	0.000	0.420	0.580
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.420	0.580
E06.1 Subacute thyroiditis	0.000	0.420	0.580
E06.0 Acute thyroiditis	0.000	0.420	0.580
E27.1 Primary adrenocortical insufficiency	0.000	0.420	0.580
E89.3 Postprocedural hypopituitarism	0.000	0.427	0.573
M14.8 Arthropathies in other specified diseases classified elsewhere	0.571	0.429	0.000
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders	0.571	0.429	0.000
M14.4 Arthropathy in amyloidosis	0.571	0.429	0.000
M14.3 Lipoid dermatoarthritis	0.571	0.429	0.000
M14.2 Diabetic arthropathy	0.571	0.429	0.000
M14.1 Crystal arthropathy in other metabolic disorders	0.571	0.429	0.000
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders	0.571	0.429	0.000
E87.4 Mixed disorder of acid-base balance	0.000	0.429	0.571
M40 Kyphosis and lordosis	0.570	0.430	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.569	0.431	0.000
E21.0 Primary hyperparathyroidism	0.000	0.432	0.568
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.568	0.432	0.000
M06.48 Inflammatory polyarthropathy (Other)	0.565	0.435	0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.565	0.435	0.000
M06.46 Inflammatory polyarthropathy (Lower leg)	0.565	0.435	0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.565	0.435	0.000
M06.44 Inflammatory polyarthropathy (Hand)	0.565	0.435	0.000
M06.43 Inflammatory polyarthropathy (Forearm)	0.565	0.435	0.000
M06.42 Inflammatory polyarthropathy (Upper arm)	0.565	0.435	0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.565	0.435	0.000
E13.8 With unspecified complications	0.000	0.438	0.562
E13.7 With multiple complications	0.000	0.438	0.562
E13.6 With other specified complications	0.000	0.438	0.562
E13.5 With peripheral circulatory complications	0.000	0.438	0.562
E13.4 With neurological complications	0.000	0.438	0.562
E13.3 With ophthalmic complications	0.000	0.438	0.562
E13.2 With renal complications	0.000	0.438	0.562
E13.1 With ketoacidosis	0.000	0.438	0.562
E13.0 With coma	0.000	0.438	0.562
M10 Gout	0.562	0.438	0.000
E26 Hyperaldosteronism	0.000	0.439	0.561
E15 Nondiabetic hypoglycaemic coma	0.000	0.439	0.561
M43 Other deforming dorsopathies	0.561	0.439	0.000
M06.34 Rheumatoid nodule (Hand)	0.560	0.439	0.000
M83 Adult osteomalacia	0.558	0.442	0.000
M82 Osteoporosis in diseases classified elsewhere	0.558	0.442	0.000
E14.9 Without complications	0.000	0.443	0.557
E83.3 Disorders of phosphorus metabolism	0.000	0.445	0.555
E89.2 Postprocedural hypoparathyroidism	0.000	0.446	0.554
M62 Other disorders of muscle	0.551	0.449	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.546	0.454	0.000
E73.9 Lactose intolerance, unspecified	0.000	0.455	0.545
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.455	0.544
E32 Diseases of thymus	0.000	0.455	0.544
E31 Polyglandular dysfunction	0.000	0.455	0.544
E30 Disorders of puberty, not elsewhere classified	0.000	0.455	0.544
E25 Adrenogenital disorders	0.000	0.455	0.544
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.544	0.456	0.000
E16.2 Hypoglycaemia, unspecified	0.000	0.457	0.543
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.542	0.457	0.000
M85.0 Fibrous dysplasia (monostotic)	0.537	0.463	0.000
E07.9 Disorder of thyroid, unspecified	0.000	0.465	0.535
E20 Hypoparathyroidism	0.000	0.467	0.533
M06.39 Rheumatoid nodule (Site unspecified)	0.533	0.467	0.000
M06.38 Rheumatoid nodule (Other)	0.533	0.467	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.533	0.467	0.000
M06.36 Rheumatoid nodule (Lower leg)	0.533	0.467	0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.533	0.467	0.000
M06.33 Rheumatoid nodule (Forearm)	0.533	0.467	0.000
M06.32 Rheumatoid nodule (Upper arm)	0.533	0.467	0.000
M06.31 Rheumatoid nodule (Shoulder region)	0.533	0.467	0.000
M06.30 Rheumatoid nodule (Multiple sites)	0.533	0.467	0.000
M03 Postinfective and reactive arthropathies in diseases classified elsewhere	0.532	0.468	0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere	0.532	0.468	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.530	0.469	0.000
M50 Cervical disk disorders	0.529	0.471	0.000
E88.9 Metabolic disorder, unspecified	0.000	0.478	0.522
E88.8 Other specified metabolic disorders	0.000	0.478	0.522
E88.3 Tumour lysis syndrome	0.000	0.478	0.522
E88.2 Lipomatosis, not elsewhere classified	0.000	0.478	0.522
E88.1 Lipodystrophy, not elsewhere classified	0.000	0.478	0.522
E46 Unspecified protein-energy malnutrition	0.000	0.478	0.522
M80.0 Postmenopausal osteoporosis with pathological fracture	0.521	0.479	0.000
M92 Other juvenile osteochondrosis	0.519	0.480	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.483	0.517
E45 Retarded development following protein-energy malnutrition	0.000	0.483	0.517
E43 Unspecified severe protein-energy malnutrition	0.000	0.483	0.517
E42 Marasmic kwashiorkor	0.000	0.483	0.517
E41 Nutritional marasmus	0.000	0.483	0.517
E40 Kwashiorkor	0.000	0.483	0.517
M42 Spinal osteochondrosis	0.515	0.485	0.000
E89.0 Postprocedural hypothyroidism	0.000	0.485	0.515
M63 Disorders of muscle in diseases classified elsewhere	0.514	0.486	0.000
M61 Calcification and ossification of muscle	0.514	0.486	0.000
M60 Myositis	0.514	0.486	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.000	0.486	0.514
E89.8 Other postprocedural endocrine and metabolic disorders	0.000	0.486	0.514
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.000	0.486	0.514
E89.5 Postprocedural testicular hypofunction	0.000	0.486	0.514
E89.4 Postprocedural ovarian failure	0.000	0.486	0.514
E89.1 Postprocedural hypoinsulinaemia	0.000	0.486	0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.486	0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.486	0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.486	0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.486	0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.486	0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.486	0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.486	0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.486	0.514
E12.9 Without complications	0.000	0.487	0.513
E12.8 With unspecified complications	0.000	0.487	0.513
E12.7 With multiple complications	0.000	0.487	0.513
E12.6 With other specified complications	0.000	0.487	0.513
E12.5 With peripheral circulatory complications	0.000	0.487	0.513
E12.4 With neurological complications	0.000	0.487	0.513
E12.3 With ophthalmic complications	0.000	0.487	0.513
E12.2 With renal complications	0.000	0.487	0.513
E12.1 With ketoacidosis	0.000	0.487	0.513
E12.0 With coma	0.000	0.487	0.513
M06.19 Adult-onset Still's disease (Site unspecified)	0.513	0.487	0.000
M06.18 Adult-onset Still's disease (Other)	0.513	0.487	0.000
M06.17 Adult-onset Still's disease (Ankle and foot)	0.513	0.487	0.000
M06.16 Adult-onset Still's disease (Lower leg)	0.513	0.487	0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.513	0.487	0.000
M06.14 Adult-onset Still's disease (Hand)	0.513	0.487	0.000
M06.13 Adult-onset Still's disease (Forearm)	0.513	0.487	0.000
M06.12 Adult-onset Still's disease (Upper arm)	0.513	0.487	0.000
M06.11 Adult-onset Still's disease (Shoulder region)	0.513	0.487	0.000
M06.10 Adult-onset Still's disease (Multiple sites)	0.513	0.487	0.000
M06.29 Rheumatoid bursitis (Site unspecified)	0.513	0.487	0.000
M06.28 Rheumatoid bursitis (Other)	0.513	0.487	0.000
M06.27 Rheumatoid bursitis (Ankle and foot)	0.513	0.487	0.000
M06.26 Rheumatoid bursitis (Lower leg)	0.513	0.487	0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.513	0.487	0.000
M06.24 Rheumatoid bursitis (Hand)	0.513	0.487	0.000
M06.23 Rheumatoid bursitis (Forearm)	0.513	0.487	0.000
M06.22 Rheumatoid bursitis (Upper arm)	0.513	0.487	0.000
M06.21 Rheumatoid bursitis (Shoulder region)	0.513	0.487	0.000
M06.20 Rheumatoid bursitis (Multiple sites)	0.513	0.487	0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.513	0.487	0.000
M06.88 Other specified rheumatoid arthritis (Other)	0.513	0.487	0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.513	0.487	0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.513	0.487	0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.513	0.487	0.000
M06.84 Other specified rheumatoid arthritis (Hand)	0.513	0.487	0.000
M06.83 Other specified rheumatoid arthritis (Forearm)	0.513	0.487	0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.513	0.487	0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.513	0.487	0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.513	0.487	0.000
E14.8 With unspecified complications	0.000	0.487	0.513
E14.7 With multiple complications	0.000	0.487	0.513
E14.6 With other specified complications	0.000	0.487	0.513
E14.5 With peripheral circulatory complications	0.000	0.487	0.513
E14.4 With neurological complications	0.000	0.487	0.513
E14.2 Withrenal complications	0.000	0.487	0.513
E14.1 With ketoacidosis	0.000	0.487	0.513
E14.0 With coma	0.000	0.487	0.513
E07.1 Dyshormogenetic goitre	0.000	0.488	0.512
E07.0 Hypersecretion of calcitonin	0.000	0.488	0.512
M02.3 Reiter's disease	0.512	0.488	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.511	0.489	0.000
M08.9 Juvenile arthritis, unspecified	0.510	0.490	0.000
M08.8 Other juvenile arthritis	0.510	0.490	0.000
M08.4 Pauciarticular juvenile arthritis	0.510	0.490	0.000
M08.3 Juvenile polyarthritis (seronegative)	0.510	0.490	0.000
M08.2 Juvenile arthritis with systemic onset	0.510	0.490	0.000
M08.1 Juvenile ankylosing spondylitis	0.510	0.490	0.000
M08.0 Juvenile rheumatoid arthritis	0.510	0.490	0.000
M09.8 Juvenile arthritis in other diseases classified elsewhere	0.510	0.490	0.000
M09.2 Juvenile arthritis in ulcerative colitis	0.510	0.490	0.000
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]	0.510	0.490	0.000
M09.0 Juvenile arthritis in psoriasis	0.510	0.490	0.000
M12.8 Other specific arthropathies, not elsewhere classified	0.510	0.490	0.000
M12.5 Traumatic arthropathy	0.510	0.490	0.000
M12.4 Intermittent hydrarthrosis	0.510	0.490	0.000
M12.3 Palindromic rheumatism	0.510	0.490	0.000
M12.2 Villonodular synovitis (pigmented)	0.510	0.490	0.000
M12.1 Kaschin-Beck disease	0.510	0.490	0.000
M12.0 Chronic postrheumatic arthropathy [Jaccoud]	0.510	0.490	0.000
M00 Pyogenic arthritis	0.508	0.491	0.000
E34 Other endocrine disorders	0.000	0.495	0.505
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.505	0.495	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.505	0.495	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.505	0.495	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.505	0.495	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.505	0.495	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.505	0.495	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.505	0.495	0.000
M65-M68 Disorders of synovium and tendon	0.503	0.497	0.000
E87.3 Alkalosis	0.000	0.499	0.500
M85.6 Other cyst of bone	0.500	0.500	0.000
E24 Cushing's syndrome	0.000	0.502	0.498
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)	0.498	0.502	0.000
M07.08 Distal interphalangeal proriatic arthropathy-Other	0.498	0.502	0.000
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)	0.498	0.502	0.000
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg	0.498	0.502	0.000
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh	0.498	0.502	0.000
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)	0.498	0.502	0.000
M07.03 Distal interphalangeal proriatic arthropathy-Forearm	0.498	0.502	0.000
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm	0.498	0.502	0.000
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region	0.498	0.502	0.000
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)	0.498	0.502	0.000
M07.19 Arthritis mutilans (Site unspecified)	0.498	0.502	0.000
M07.18 Arthritis mutilans (Other)	0.498	0.502	0.000
M07.17 Arthritis mutilans (Ankle and foot)	0.498	0.502	0.000
M07.16 Arthritis mutilans (Lower leg)	0.498	0.502	0.000
M07.15 Arthritis mutilans (Pelvic region and thigh)	0.498	0.502	0.000
M07.14 Arthritis mutilans (Hand)	0.498	0.502	0.000
M07.13 Arthritis mutilans (Forearm)	0.498	0.502	0.000
M07.12 Arthritis mutilans (Upper arm)	0.498	0.502	0.000
M07.11 Arthritis mutilans (Shoulder region)	0.498	0.502	0.000
M07.10 Arthritis mutilans (Multiple sites)	0.498	0.502	0.000
M07.29 Psoriatic spondylitis (Site unspecified)	0.498	0.502	0.000
M07.28 Psoriatic spondylitis (Other)	0.498	0.502	0.000
M07.27 Psoriatic spondylitis (Ankle and foot)	0.498	0.502	0.000
M07.26 Psoriatic spondylitis (Lower leg)	0.498	0.502	0.000
M07.25 Psoriatic spondylitis (Pelvic region and thigh)	0.498	0.502	0.000
M07.24 Psoriatic spondylitis (Hand)	0.498	0.502	0.000
M07.23 Psoriatic spondylitis (Forearm)	0.498	0.502	0.000
M07.22 Psoriatic spondylitis (Upper arm)	0.498	0.502	0.000
M07.21 Psoriatic spondylitis (Shoulder region)	0.498	0.502	0.000
M07.20 Psoriatic spondylitis (Multiple sites)	0.498	0.502	0.000
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)	0.498	0.502	0.000
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)	0.498	0.502	0.000
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)	0.498	0.502	0.000
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)	0.498	0.502	0.000
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)	0.498	0.502	0.000
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)	0.498	0.502	0.000
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)	0.498	0.502	0.000
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)	0.498	0.502	0.000
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)	0.498	0.502	0.000
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)	0.498	0.502	0.000
M07.59 Arthropathy in ulcerative colitis (Site unspecified)	0.498	0.502	0.000
M07.58 Arthropathy in ulcerative colitis (Other)	0.498	0.502	0.000
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)	0.498	0.502	0.000
M07.56 Arthropathy in ulcerative colitis (Lower leg)	0.498	0.502	0.000
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)	0.498	0.502	0.000
M07.54 Arthropathy in ulcerative colitis (Hand)	0.498	0.502	0.000
M07.53 Arthropathy in ulcerative colitis (Forearm)	0.498	0.502	0.000
M07.52 Arthropathy in ulcerative colitis (Upper arm)	0.498	0.502	0.000
M07.51 Arthropathy in ulcerative colitis (Shoulder region)	0.498	0.502	0.000
M07.50 Arthropathy in ulcerative colitis (Multiple sites)	0.498	0.502	0.000
M07.69 Other enteropathic arthropathies (Site unspecified)	0.498	0.502	0.000
M07.68 Other enteropathic arthropathies (Other)	0.498	0.502	0.000
M07.67 Other enteropathic arthropathies (Ankle and foot)	0.498	0.502	0.000
M07.66 Other enteropathic arthropathies (Lower leg)	0.498	0.502	0.000
M07.65 Other enteropathic arthropathies (Pelvic region and thigh)	0.498	0.502	0.000
M07.64 Other enteropathic arthropathies (Hand)	0.498	0.502	0.000
M07.63 Other enteropathic arthropathies (Forearm)	0.498	0.502	0.000
M07.62 Other enteropathic arthropathies (Upper arm)	0.498	0.502	0.000
M07.61 Other enteropathic arthropathies (Shoulder region)	0.498	0.502	0.000
M07.60 Other enteropathic arthropathies (Multiple sites)	0.498	0.502	0.000
E28 Ovarian dysfunction	0.000	0.503	0.497
M13 Other arthritis	0.497	0.503	0.000
M88 Paget's disease of bone [osteitis deformans]	0.495	0.505	0.000
M80.8 Other osteoporosis with pathological fracture	0.495	0.505	0.000
M80.5 Idiopathic osteoporosis with pathological fracture	0.495	0.505	0.000
M80.4 Drug-induced osteoporosis with pathological fracture	0.495	0.505	0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.495	0.505	0.000
M80.2 Osteoporosis of disuse with pathological fracture	0.495	0.505	0.000
E73.8 Other lactose intolerance	0.000	0.510	0.490
E73.1 Secondary lactase deficiency	0.000	0.510	0.490
E73.0 Congenital lactase deficiency	0.000	0.510	0.490
M11.9 Crystal arthropathy, unspecified	0.489	0.511	0.000
M11.8 Other specified crystal arthropathies	0.489	0.511	0.000
M11.1 Familial chondrocalcinosis	0.489	0.511	0.000
M11.0 Hydroxyapatite deposition disease	0.489	0.511	0.000
E22.0 Acromegaly and pituitary gigantism	0.000	0.511	0.489
M89 Other disorders of bone	0.488	0.511	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.515	0.485
E07.8 Other specified disorders of thyroid	0.000	0.516	0.484
M84 Disorders of continuity of bone	0.483	0.517	0.000
M49.8 Spondylopathy in other diseases classified elsewhere	0.481	0.518	0.000
M49.4 Neuropathic spondylopathy	0.481	0.518	0.000
M49.3 Spondylopathy in other infectious and parasitic diseases classified elsewhere	0.481	0.518	0.000
M49.2 Enterobacterial spondylitis	0.481	0.518	0.000
M49.1 Brucella spondylitis	0.481	0.518	0.000
M49.0 Tuberculosis of spine	0.481	0.518	0.000
M91 Juvenile osteochondrosis of hip and pelvis	0.481	0.519	0.000
M48 Other spondylopathies	0.473	0.527	0.000
E83.9 Disorder of mineral metabolism, unspecified	0.000	0.527	0.472
E83.8 Other disorders of mineral metabolism	0.000	0.527	0.472
E83.2 Disorders of zinc metabolism	0.000	0.527	0.472
E83.0 Disorders of copper metabolism	0.000	0.527	0.472
M50.2 Other cervical disk displacement	0.472	0.528	0.000
E83.5 Disorders of calcium metabolism	0.000	0.528	0.472
E83.1 Disorders of iron metabolism	0.000	0.529	0.471
M70-M79 Other soft tissue disorders	0.471	0.529	0.000
M49.5 Collapsed vertebra in diseases classified elsewhere	0.469	0.531	0.000
E04.9 Non-toxic goitre, unspecified	0.000	0.536	0.464
M40.2 Other and unspecified kyphosis	0.464	0.536	0.000
M86 Osteomyelitis	0.463	0.537	0.000
M85.9 Disorder of bone density and structure, unspecified	0.462	0.538	0.000
M85.5 Aneurysmal bone cyst	0.462	0.538	0.000
M85.4 Solitary bone cyst	0.462	0.538	0.000
M85.3 Osteitis condensans	0.462	0.538	0.000
M85.2 Hyperostosis of skull	0.462	0.538	0.000
M85.1 Skeletal fluorosis	0.462	0.538	0.000
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)	0.460	0.540	0.000
M11.2 Other chondrocalcinosis	0.459	0.541	0.000
E53.8 Deficiency of other specified B group vitamins	0.000	0.542	0.458
E21.5 Disorder of parathyroid gland, unspecified	0.000	0.542	0.457
E21.4 Other specified disorders of parathyroid gland	0.000	0.542	0.457
E21.2 Other hyperparathyroidism	0.000	0.542	0.457
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.000	0.542	0.457
E53.9 Vitamin B deficiency, unspecified	0.000	0.543	0.456
E53.1 Pyridoxine deficiency	0.000	0.543	0.456
E53.0 Riboflavin deficiency	0.000	0.543	0.456
M94 Other disorders of cartilage	0.456	0.544	0.000
E50.9 Vitamin A deficiency, unspecified	0.000	0.544	0.455
E50.8 Other manifestations of vitamin A deficiency	0.000	0.544	0.455
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.544	0.455
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.544	0.455
E50.5 Vitamin A deficiency with night blindness	0.000	0.544	0.455
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.544	0.455
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.544	0.455
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.544	0.455
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.544	0.455
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.544	0.455
E51.9 Thiamine deficiency, unspecified	0.000	0.544	0.455
E51.8 Other manifestations of thiamine deficiency	0.000	0.544	0.455

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations