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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs9366776
log Bayes Factor = 11.525
Chromosome 6   position 31,256,630  (GRCh37) Explore rs9366776 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M45.X9 Ankylosing spondylitis (Site unspecified)
1.000 0.000 0.000
E03.9 Hypothyroidism, unspecified
0.000 0.002 0.998
E00-E07 Disorders of thyroid gland
0.000 0.003 0.997
E03 Other hypothyroidism
0.000 0.003 0.997
M06.9 Rheumatoid arthritis, unspecified
0.997 0.003 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.996 0.004 0.000
M45 Ankylosing spondylitis
0.995 0.005 0.000
E10 Insulin-dependent diabetes mellitus
0.000 0.005 0.995
M06 Other rheumatoid arthritis
0.995 0.005 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.006 0.994
E10-E14 Diabetes mellitus
0.000 0.007 0.993
E10.9 Without complications
0.000 0.015 0.985
M05-M14 Inflammatory polyarthropathies
0.983 0.017 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.976 0.024 0.000
M07 Psoriatic and enteropathic arthropathies
0.958 0.042 0.000
E10.1 With ketoacidosis
0.000 0.047 0.953
M07.3 Other psoriatic arthropathies
0.940 0.060 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.062 0.938
M45-M49 Spondylopathies
0.936 0.064 0.000
M06.0 Seronegative rheumatoid arthritis
0.935 0.065 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.928 0.072 0.000
E10.3 With ophthalmic complications
0.000 0.072 0.928
M07.30 Other psoriatic arthropathies (Multiple sites)
0.890 0.110 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.887 0.113 0.000
E50-E64 Other nutritional deficiencies
0.000 0.115 0.885
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.124 0.876
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.872 0.128 0.000
E10.4 With neurological complications
0.000 0.131 0.869
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.864 0.136 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.861 0.139 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.829 0.171 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.816 0.184 0.000
E04 Other non-toxic goitre
0.000 0.184 0.816
E06 Thyroiditis
0.000 0.187 0.813
E55 Vitamin D deficiency
0.000 0.195 0.805
E20-E35 Disorders of other endocrine glands
0.000 0.201 0.799
E10.5 With peripheral circulatory complications
0.000 0.206 0.794
M14 Arthropathies in other diseases classified elsewhere
0.792 0.208 0.000
M06.4 Inflammatory polyarthropathy
0.784 0.216 0.000
M05 Seropositive rheumatoid arthritis
0.781 0.219 0.000
K90.0 Coeliac disease
0.000 0.219 0.781
E07 Other disorders of thyroid
0.000 0.223 0.777
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.773 0.227 0.000
E13 Other specified diabetes mellitus
0.000 0.239 0.761
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.758 0.242 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.755 0.245 0.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.245 0.755
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.753 0.247 0.000
M45.X2 Ankylosing spondylitis (Cervical region)
0.752 0.248 0.000
E55.9 Vitamin D deficiency, unspecified
0.000 0.252 0.748
M06.3 Rheumatoid nodule
0.739 0.261 0.000
E40-E46 Malnutrition
0.000 0.263 0.737
M00-M03 Infectious arthropathies
0.726 0.274 0.000
E70-E90 Metabolic disorders
0.000 0.277 0.723
M80-M85 Disorders of bone density and structure
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.285 0.715
E00 Congenital iodine-deficiency syndrome
0.000 0.285 0.715
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.285 0.715
E03.5 Myxoedema coma
0.000 0.285 0.715
E03.4 Atrophy of thyroid (acquired)
0.000 0.285 0.715
E03.3 Postinfectious hypothyroidism
0.000 0.285 0.715
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.285 0.715
E03.1 Congenital hypothyroidism without goitre
0.000 0.285 0.715
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.285 0.715
M06.98 Rheumatoid arthritis, unspecified (Other)
0.715 0.285 0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.713 0.286 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.713 0.286 0.000
M45.X6 Ankylosing spondylitis (Lumbar region)
0.713 0.286 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.713 0.286 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.713 0.286 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.713 0.286 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.713 0.286 0.000
E10.8 With unspecified complications
0.000 0.287 0.713
E10.7 With multiple complications
0.000 0.287 0.713
E10.0 With coma
0.000 0.287 0.713
M06.8 Other specified rheumatoid arthritis
0.713 0.287 0.000
M06.2 Rheumatoid bursitis
0.713 0.287 0.000
M06.1 Adult-onset Still's disease
0.713 0.287 0.000
E12 Malnutrition-related diabetes mellitus
0.000 0.288 0.712
E04.2 Non-toxic multinodular goitre
0.000 0.294 0.706
M12 Other specific arthropathies
0.705 0.295 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.705 0.295 0.000
M08 Juvenile arthritis
0.705 0.295 0.000
M60-M63 Disorders of muscles
0.698 0.302 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.302 0.698
E27 Other disorders of adrenal gland
0.000 0.307 0.693
E10.2 With renal complications
0.000 0.308 0.691
M07.6 Other enteropathic arthropathies
0.687 0.313 0.000
M07.5 Arthropathy in ulcerative colitis
0.687 0.313 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.687 0.313 0.000
M07.2 Psoriatic spondylitis
0.687 0.313 0.000
M07.1 Arthritis mutilans
0.687 0.313 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.687 0.313 0.000
M11 Other crystal arthropathies
0.679 0.321 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.324 0.676
M07.38 Other psoriatic arthropathies (Other)
0.674 0.326 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.674 0.326 0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.674 0.326 0.000
M07.34 Other psoriatic arthropathies (Hand)
0.674 0.326 0.000
M07.33 Other psoriatic arthropathies (Forearm)
0.674 0.326 0.000
M07.32 Other psoriatic arthropathies (Upper arm)
0.674 0.326 0.000
M07.31 Other psoriatic arthropathies (Shoulder region)
0.674 0.326 0.000
E05.8 Other thyrotoxicosis
0.000 0.327 0.672
E05.5 Thyroid crisis or storm
0.000 0.327 0.672
E05.4 Thyrotoxicosis factitia
0.000 0.327 0.672
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.327 0.672
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.327 0.672
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.329 0.671
M49 Spondylopathies in diseases classified elsewhere
0.671 0.329 0.000
M06.08 Seronegative rheumatoid arthritis (Other)
0.670 0.330 0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.670 0.330 0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.670 0.330 0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.670 0.330 0.000
M06.04 Seronegative rheumatoid arthritis (Hand)
0.670 0.330 0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.670 0.330 0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.670 0.330 0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.670 0.330 0.000
E06.3 Autoimmune thyroiditis
0.000 0.334 0.666
E53 Deficiency of other B group vitamins
0.000 0.334 0.666
M40-M43 Deforming dorsopathies
0.665 0.335 0.000
E22 Hyperfunction of pituitary gland
0.000 0.339 0.661
E03.8 Other specified hypothyroidism
0.000 0.339 0.660
E04.1 Non-toxic single thyroid nodule
0.000 0.341 0.659
M14.6 Neuropathic arthropathy
0.655 0.345 0.000
M91-M94 Chondropathies
0.654 0.346 0.000
E27.1 Primary adrenocortical insufficiency
0.000 0.347 0.653
E14 Unspecified diabetes mellitus
0.000 0.350 0.650
M86-M90 Other osteopathies
0.648 0.351 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.645 0.355 0.000
E07.9 Disorder of thyroid, unspecified
0.000 0.361 0.639
M05.9 Seropositive rheumatoid arthritis, unspecified
0.637 0.363 0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.634 0.366 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.366 0.634
E63 Other nutritional deficiencies
0.000 0.366 0.634
E56 Other vitamin deficiencies
0.000 0.366 0.634
E51 Thiamine deficiency
0.000 0.366 0.634
E50 Vitamin A deficiency
0.000 0.366 0.634
E60 Dietary zinc deficiency
0.000 0.366 0.634
E59 Dietary selenium deficiency
0.000 0.366 0.634
E58 Dietary calcium deficiency
0.000 0.366 0.634
E54 Ascorbic acid deficiency
0.000 0.366 0.634
E52 Niacin deficiency [pellagra]
0.000 0.366 0.634
E10.6 With other specified complications
0.000 0.372 0.628
M46 Other inflammatory spondylopathies
0.623 0.377 0.000
M80 Osteoporosis with pathological fracture
0.621 0.379 0.000
E21.0 Primary hyperparathyroidism
0.000 0.388 0.612
E06.9 Thyroiditis, unspecified
0.000 0.394 0.606
E88 Other metabolic disorders
0.000 0.397 0.603
E61 Deficiency of other nutrient elements
0.000 0.398 0.602
M02 Reactive arthropathies
0.595 0.405 0.000
E13.9 Without complications
0.000 0.406 0.594
E26 Hyperaldosteronism
0.000 0.409 0.591
E04.0 Non-toxic diffuse goitre
0.000 0.409 0.591
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.410 0.590
E04.8 Other specified non-toxic goitre
0.000 0.415 0.585
E06.5 Other chronic thyroiditis
0.000 0.417 0.583
E06.4 Drug-induced thyroiditis
0.000 0.417 0.583
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.417 0.583
E06.1 Subacute thyroiditis
0.000 0.417 0.583
E06.0 Acute thyroiditis
0.000 0.417 0.583
E55.0 Rickets, active
0.000 0.423 0.577
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.427 0.573
E32 Diseases of thymus
0.000 0.427 0.573
E31 Polyglandular dysfunction
0.000 0.427 0.573
E30 Disorders of puberty, not elsewhere classified
0.000 0.427 0.573
E25 Adrenogenital disorders
0.000 0.427 0.573
M14.8 Arthropathies in other specified diseases classified elsewhere
0.568 0.432 0.000
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.568 0.432 0.000
M14.4 Arthropathy in amyloidosis
0.568 0.432 0.000
M14.3 Lipoid dermatoarthritis
0.568 0.432 0.000
M14.2 Diabetic arthropathy
0.568 0.432 0.000
M14.1 Crystal arthropathy in other metabolic disorders
0.568 0.432 0.000
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.568 0.432 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.434 0.566
M85 Other disorders of bone density and structure
0.565 0.435 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.563 0.437 0.000
M06.48 Inflammatory polyarthropathy (Other)
0.562 0.438 0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.562 0.438 0.000
M06.46 Inflammatory polyarthropathy (Lower leg)
0.562 0.438 0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.562 0.438 0.000
M06.44 Inflammatory polyarthropathy (Hand)
0.562 0.438 0.000
M06.43 Inflammatory polyarthropathy (Forearm)
0.562 0.438 0.000
M06.42 Inflammatory polyarthropathy (Upper arm)
0.562 0.438 0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.562 0.438 0.000
M10 Gout
0.561 0.439 0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.560 0.440 0.000
M05.8 Other seropositive rheumatoid arthritis
0.560 0.440 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.560 0.440 0.000
M05.2 Rheumatoid vasculitis
0.560 0.440 0.000
M05.1 Rheumatoid lung disease
0.560 0.440 0.000
M05.0 Felty's syndrome
0.560 0.440 0.000
E20 Hypoparathyroidism
0.000 0.440 0.559
E07.1 Dyshormogenetic goitre
0.000 0.443 0.557
E07.0 Hypersecretion of calcitonin
0.000 0.443 0.557
M06.34 Rheumatoid nodule (Hand)
0.556 0.443 0.000
E46 Unspecified protein-energy malnutrition
0.000 0.447 0.553
E73 Lactose intolerance
0.000 0.447 0.552
E13.8 With unspecified complications
0.000 0.454 0.545
E13.7 With multiple complications
0.000 0.454 0.545
E13.6 With other specified complications
0.000 0.454 0.545
E13.5 With peripheral circulatory complications
0.000 0.454 0.545
E13.4 With neurological complications
0.000 0.454 0.545
E13.3 With ophthalmic complications
0.000 0.454 0.545
E13.2 With renal complications
0.000 0.454 0.545
E13.1 With ketoacidosis
0.000 0.454 0.545
E13.0 With coma
0.000 0.454 0.545
M50-M54 Other dorsopathies
0.544 0.456 0.000
E83 Disorders of mineral metabolism
0.000 0.458 0.542
E85 Amyloidosis
0.000 0.459 0.541
E86 Volume depletion
0.000 0.460 0.540
E87.6 Hypokalaemia
0.000 0.462 0.538
E28 Ovarian dysfunction
0.000 0.462 0.537
E22.0 Acromegaly and pituitary gigantism
0.000 0.464 0.536
M62 Other disorders of muscle
0.533 0.467 0.000
E34 Other endocrine disorders
0.000 0.469 0.531
M06.39 Rheumatoid nodule (Site unspecified)
0.530 0.470 0.000
M06.38 Rheumatoid nodule (Other)
0.530 0.470 0.000
M06.37 Rheumatoid nodule (Ankle and foot)
0.530 0.470 0.000
M06.36 Rheumatoid nodule (Lower leg)
0.530 0.470 0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.530 0.470 0.000
M06.33 Rheumatoid nodule (Forearm)
0.530 0.470 0.000
M06.32 Rheumatoid nodule (Upper arm)
0.530 0.470 0.000
M06.31 Rheumatoid nodule (Shoulder region)
0.530 0.470 0.000
M06.30 Rheumatoid nodule (Multiple sites)
0.530 0.470 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.471 0.528
E45 Retarded development following protein-energy malnutrition
0.000 0.471 0.528
E43 Unspecified severe protein-energy malnutrition
0.000 0.471 0.528
E42 Marasmic kwashiorkor
0.000 0.471 0.528
E41 Nutritional marasmus
0.000 0.471 0.528
E40 Kwashiorkor
0.000 0.471 0.528
M40 Kyphosis and lordosis
0.528 0.472 0.000
E07.8 Other specified disorders of thyroid
0.000 0.475 0.525
M20-M25 Other joint disorders
0.525 0.475 0.000
E24 Cushing's syndrome
0.000 0.477 0.523
M03 Postinfective and reactive arthropathies in diseases classified elsewhere
0.520 0.480 0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere
0.520 0.480 0.000
E84 Cystic fibrosis
0.000 0.482 0.518
E79 Disorders of purine and pyrimidine metabolism
0.000 0.482 0.518
E77 Disorders of glycoprotein metabolism
0.000 0.482 0.518
E76 Disorders of glycosaminoglycan metabolism
0.000 0.482 0.518
E72 Other disorders of amino-acid metabolism
0.000 0.482 0.518
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.482 0.518
E70 Disorders of aromatic amino-acid metabolism
0.000 0.482 0.518
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.482 0.518
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.482 0.518
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.515 0.485 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.485 0.515
M80.9 Unspecified osteoporosis with pathological fracture
0.515 0.485 0.000
M83 Adult osteomalacia
0.514 0.486 0.000
M82 Osteoporosis in diseases classified elsewhere
0.514 0.486 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.487 0.513
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.487 0.513
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.487 0.513
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.487 0.513
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.487 0.513
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.487 0.513
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.487 0.513
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.487 0.513
M06.19 Adult-onset Still's disease (Site unspecified)
0.511 0.489 0.000
M06.18 Adult-onset Still's disease (Other)
0.511 0.489 0.000
M06.17 Adult-onset Still's disease (Ankle and foot)
0.511 0.489 0.000
M06.16 Adult-onset Still's disease (Lower leg)
0.511 0.489 0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.511 0.489 0.000
M06.14 Adult-onset Still's disease (Hand)
0.511 0.489 0.000
M06.13 Adult-onset Still's disease (Forearm)
0.511 0.489 0.000
M06.12 Adult-onset Still's disease (Upper arm)
0.511 0.489 0.000
M06.11 Adult-onset Still's disease (Shoulder region)
0.511 0.489 0.000
M06.10 Adult-onset Still's disease (Multiple sites)
0.511 0.489 0.000
M06.29 Rheumatoid bursitis (Site unspecified)
0.511 0.489 0.000
M06.28 Rheumatoid bursitis (Other)
0.511 0.489 0.000
M06.27 Rheumatoid bursitis (Ankle and foot)
0.511 0.489 0.000
M06.26 Rheumatoid bursitis (Lower leg)
0.511 0.489 0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.511 0.489 0.000
M06.24 Rheumatoid bursitis (Hand)
0.511 0.489 0.000
M06.23 Rheumatoid bursitis (Forearm)
0.511 0.489 0.000
M06.22 Rheumatoid bursitis (Upper arm)
0.511 0.489 0.000
M06.21 Rheumatoid bursitis (Shoulder region)
0.511 0.489 0.000
M06.20 Rheumatoid bursitis (Multiple sites)
0.511 0.489 0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.511 0.489 0.000
M06.88 Other specified rheumatoid arthritis (Other)
0.511 0.489 0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.511 0.489 0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.511 0.489 0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.511 0.489 0.000
M06.84 Other specified rheumatoid arthritis (Hand)
0.511 0.489 0.000
M06.83 Other specified rheumatoid arthritis (Forearm)
0.511 0.489 0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.511 0.489 0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.511 0.489 0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.511 0.489 0.000
E12.9 Without complications
0.000 0.489 0.511
E12.8 With unspecified complications
0.000 0.489 0.511
E12.7 With multiple complications
0.000 0.489 0.511
E12.6 With other specified complications
0.000 0.489 0.511
E12.5 With peripheral circulatory complications
0.000 0.489 0.511
E12.4 With neurological complications
0.000 0.489 0.511
E12.3 With ophthalmic complications
0.000 0.489 0.511
E12.2 With renal complications
0.000 0.489 0.511
E12.1 With ketoacidosis
0.000 0.489 0.511
E12.0 With coma
0.000 0.489 0.511
E53.8 Deficiency of other specified B group vitamins
0.000 0.490 0.509
E74 Other disorders of carbohydrate metabolism
0.000 0.491 0.509
M92 Other juvenile osteochondrosis
0.507 0.493 0.000
M08.9 Juvenile arthritis, unspecified
0.505 0.494 0.000
M08.8 Other juvenile arthritis
0.505 0.494 0.000
M08.4 Pauciarticular juvenile arthritis
0.505 0.494 0.000
M08.3 Juvenile polyarthritis (seronegative)
0.505 0.494 0.000
M08.2 Juvenile arthritis with systemic onset
0.505 0.494 0.000
M08.1 Juvenile ankylosing spondylitis
0.505 0.494 0.000
M08.0 Juvenile rheumatoid arthritis
0.505 0.494 0.000
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.505 0.494 0.000
M09.2 Juvenile arthritis in ulcerative colitis
0.505 0.494 0.000
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.505 0.494 0.000
M09.0 Juvenile arthritis in psoriasis
0.505 0.494 0.000
M12.8 Other specific arthropathies, not elsewhere classified
0.505 0.494 0.000
M12.5 Traumatic arthropathy
0.505 0.494 0.000
M12.4 Intermittent hydrarthrosis
0.505 0.494 0.000
M12.3 Palindromic rheumatism
0.505 0.494 0.000
M12.2 Villonodular synovitis (pigmented)
0.505 0.494 0.000
M12.1 Kaschin-Beck disease
0.505 0.494 0.000
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.505 0.494 0.000
M89 Other disorders of bone
0.504 0.496 0.000
M02.3 Reiter's disease
0.502 0.498 0.000
E15 Nondiabetic hypoglycaemic coma
0.000 0.499 0.500
M63 Disorders of muscle in diseases classified elsewhere
0.500 0.499 0.000
M61 Calcification and ossification of muscle
0.500 0.499 0.000
M60 Myositis
0.500 0.499 0.000
E27.5 Adrenomedullary hyperfunction
0.000 0.503 0.497
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.503 0.497
E27.2 Addisonian crisis
0.000 0.503 0.497
E27.0 Other adrenocortical overactivity
0.000 0.503 0.497
M00 Pyogenic arthritis
0.497 0.503 0.000
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)
0.492 0.507 0.000
M07.08 Distal interphalangeal proriatic arthropathy-Other
0.492 0.507 0.000
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)
0.492 0.507 0.000
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg
0.492 0.507 0.000
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh
0.492 0.507 0.000
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)
0.492 0.507 0.000
M07.03 Distal interphalangeal proriatic arthropathy-Forearm
0.492 0.507 0.000
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm
0.492 0.507 0.000
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region
0.492 0.507 0.000
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)
0.492 0.507 0.000
M07.19 Arthritis mutilans (Site unspecified)
0.492 0.507 0.000
M07.18 Arthritis mutilans (Other)
0.492 0.507 0.000
M07.17 Arthritis mutilans (Ankle and foot)
0.492 0.507 0.000
M07.16 Arthritis mutilans (Lower leg)
0.492 0.507 0.000
M07.15 Arthritis mutilans (Pelvic region and thigh)
0.492 0.507 0.000
M07.14 Arthritis mutilans (Hand)
0.492 0.507 0.000
M07.13 Arthritis mutilans (Forearm)
0.492 0.507 0.000
M07.12 Arthritis mutilans (Upper arm)
0.492 0.507 0.000
M07.11 Arthritis mutilans (Shoulder region)
0.492 0.507 0.000
M07.10 Arthritis mutilans (Multiple sites)
0.492 0.507 0.000
M07.29 Psoriatic spondylitis (Site unspecified)
0.492 0.507 0.000
M07.28 Psoriatic spondylitis (Other)
0.492 0.507 0.000
M07.27 Psoriatic spondylitis (Ankle and foot)
0.492 0.507 0.000
M07.26 Psoriatic spondylitis (Lower leg)
0.492 0.507 0.000
M07.25 Psoriatic spondylitis (Pelvic region and thigh)
0.492 0.507 0.000
M07.24 Psoriatic spondylitis (Hand)
0.492 0.507 0.000
M07.23 Psoriatic spondylitis (Forearm)
0.492 0.507 0.000
M07.22 Psoriatic spondylitis (Upper arm)
0.492 0.507 0.000
M07.21 Psoriatic spondylitis (Shoulder region)
0.492 0.507 0.000
M07.20 Psoriatic spondylitis (Multiple sites)
0.492 0.507 0.000
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)
0.492 0.507 0.000
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)
0.492 0.507 0.000
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)
0.492 0.507 0.000
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)
0.492 0.507 0.000
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)
0.492 0.507 0.000
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)
0.492 0.507 0.000
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)
0.492 0.507 0.000
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)
0.492 0.507 0.000
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)
0.492 0.507 0.000
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)
0.492 0.507 0.000
M07.59 Arthropathy in ulcerative colitis (Site unspecified)
0.492 0.507 0.000
M07.58 Arthropathy in ulcerative colitis (Other)
0.492 0.507 0.000
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)
0.492 0.507 0.000
M07.56 Arthropathy in ulcerative colitis (Lower leg)
0.492 0.507 0.000
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)
0.492 0.507 0.000
M07.54 Arthropathy in ulcerative colitis (Hand)
0.492 0.507 0.000
M07.53 Arthropathy in ulcerative colitis (Forearm)
0.492 0.507 0.000
M07.52 Arthropathy in ulcerative colitis (Upper arm)
0.492 0.507 0.000
M07.51 Arthropathy in ulcerative colitis (Shoulder region)
0.492 0.507 0.000
M07.50 Arthropathy in ulcerative colitis (Multiple sites)
0.492 0.507 0.000
M07.69 Other enteropathic arthropathies (Site unspecified)
0.492 0.507 0.000
M07.68 Other enteropathic arthropathies (Other)
0.492 0.507 0.000
M07.67 Other enteropathic arthropathies (Ankle and foot)
0.492 0.507 0.000
M07.66 Other enteropathic arthropathies (Lower leg)
0.492 0.507 0.000
M07.65 Other enteropathic arthropathies (Pelvic region and thigh)
0.492 0.507 0.000
M07.64 Other enteropathic arthropathies (Hand)
0.492 0.507 0.000
M07.63 Other enteropathic arthropathies (Forearm)
0.492 0.507 0.000
M07.62 Other enteropathic arthropathies (Upper arm)
0.492 0.507 0.000
M07.61 Other enteropathic arthropathies (Shoulder region)
0.492 0.507 0.000
M07.60 Other enteropathic arthropathies (Multiple sites)
0.492 0.507 0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture
0.488 0.512 0.000
M50 Cervical disk disorders
0.487 0.513 0.000
M11.9 Crystal arthropathy, unspecified
0.487 0.513 0.000
M11.8 Other specified crystal arthropathies
0.487 0.513 0.000
M11.1 Familial chondrocalcinosis
0.487 0.513 0.000
M11.0 Hydroxyapatite deposition disease
0.487 0.513 0.000
E16 Other disorders of pancreatic internal secretion
0.000 0.514 0.486
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.515 0.485
E21.4 Other specified disorders of parathyroid gland
0.000 0.515 0.485
E21.2 Other hyperparathyroidism
0.000 0.515 0.485
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.515 0.485
M49.8 Spondylopathy in other diseases classified elsewhere
0.481 0.519 0.000
M49.5 Collapsed vertebra in diseases classified elsewhere
0.481 0.519 0.000
M49.4 Neuropathic spondylopathy
0.481 0.519 0.000
M49.3 Spondylopathy in other infectious and parasitic diseases classified elsewhere
0.481 0.519 0.000
M49.2 Enterobacterial spondylitis
0.481 0.519 0.000
M49.1 Brucella spondylitis
0.481 0.519 0.000
M49.0 Tuberculosis of spine
0.481 0.519 0.000
E87.0 Hyperosmolality and hypernatraemia
0.000 0.520 0.480
M65-M68 Disorders of synovium and tendon
0.479 0.521 0.000
M86 Osteomyelitis
0.478 0.522 0.000
E53.9 Vitamin B deficiency, unspecified
0.000 0.522 0.478
E53.1 Pyridoxine deficiency
0.000 0.522 0.478
E53.0 Riboflavin deficiency
0.000 0.522 0.478
E14.9 Without complications
0.000 0.523 0.477
E29 Testicular dysfunction
0.000 0.523 0.477
M42 Spinal osteochondrosis
0.477 0.523 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.477 0.523 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.475 0.524 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.526 0.474
E22.8 Other hyperfunction of pituitary gland
0.000 0.526 0.474
E22.1 Hyperprolactinaemia
0.000 0.526 0.474
E89.3 Postprocedural hypopituitarism
0.000 0.528 0.472
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.529 0.471
M80.0 Postmenopausal osteoporosis with pathological fracture
0.471 0.529 0.000
M84 Disorders of continuity of bone
0.470 0.530 0.000
M34 Systemic sclerosis
0.470 0.530 0.000
M91 Juvenile osteochondrosis of hip and pelvis
0.469 0.531 0.000
E14.8 With unspecified complications
0.000 0.534 0.466
E14.7 With multiple complications
0.000 0.534 0.466
E14.6 With other specified complications
0.000 0.534 0.466
E14.5 With peripheral circulatory complications
0.000 0.534 0.466
E14.4 With neurological complications
0.000 0.534 0.466
E14.2 Withrenal complications
0.000 0.534 0.466
E14.1 With ketoacidosis
0.000 0.534 0.466
E14.0 With coma
0.000 0.534 0.466
E27.8 Other specified disorders of adrenal gland
0.000 0.535 0.464
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.463 0.537 0.000
M11.2 Other chondrocalcinosis
0.461 0.539 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.540 0.459
E89.2 Postprocedural hypoparathyroidism
0.000 0.543 0.457
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.456 0.543 0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.456 0.543 0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.456 0.543 0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.456 0.543 0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.456 0.543 0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.456 0.543 0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.456 0.543 0.000
E50.9 Vitamin A deficiency, unspecified
0.000 0.545 0.455
E50.8 Other manifestations of vitamin A deficiency
0.000 0.545 0.455
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.545 0.455
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.545 0.455
E50.5 Vitamin A deficiency with night blindness
0.000 0.545 0.455
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.545 0.455
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.545 0.455
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.545 0.455
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.545 0.455
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.545 0.455
E51.9 Thiamine deficiency, unspecified
0.000 0.545 0.455
E51.8 Other manifestations of thiamine deficiency
0.000 0.545 0.455
E51.2 Wernicke's encephalopathy
0.000 0.545 0.455
E51.1 Beriberi
0.000 0.545 0.455
E56.9 Vitamin deficiency, unspecified
0.000 0.545 0.455
E56.8 Deficiency of other vitamins
0.000 0.545 0.455
E56.1 Deficiency of vitamin K
0.000 0.545 0.455
E56.0 Deficiency of vitamin E
0.000 0.545 0.455
E63.9 Nutritional deficiency, unspecified
0.000 0.545 0.455
E63.8 Other specified nutritional deficiencies
0.000 0.545 0.455
E63.1 Imbalance of constituents of food intake
0.000 0.545 0.455
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.545 0.455
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.545 0.455
E64.8 Sequelae of other nutritional deficiencies
0.000 0.545 0.455
E64.3 Sequelae of rickets
0.000 0.545 0.455
E64.2 Sequelae of vitamin C deficiency
0.000 0.545 0.455
E64.1 Sequelae of vitamin A deficiency
0.000 0.545 0.455
E64.0 Sequelae of protein-energy malnutrition
0.000 0.545 0.455
M13 Other arthritis
0.453 0.547 0.000
M24 Other specific joint derangements
0.452 0.548 0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)
0.450 0.550 0.000
M88 Paget's disease of bone [osteitis deformans]
0.450 0.550 0.000
M46.4 Discitis, unspecified
0.449 0.551 0.000
M43 Other deforming dorsopathies
0.449 0.551 0.000
M90 Osteopathies in diseases classified elsewhere
0.448 0.552 0.000
M85.0 Fibrous dysplasia (monostotic)
0.448 0.552 0.000
M46.8 Other specified inflammatory spondylopathies
0.446 0.553 0.000
M46.5 Other infective spondylopathies
0.446 0.553 0.000
M46.3 Infection of intervertebral disk (pyogenic)
0.446 0.553 0.000
M46.2 Osteomyelitis of vertebra
0.446 0.553 0.000
M46.1 Sacro-iliitis, not elsewhere classified
0.446 0.553 0.000
M46.0 Spinal enthesopathy
0.446 0.553 0.000
M80.8 Other osteoporosis with pathological fracture
0.445 0.555 0.000
M80.5 Idiopathic osteoporosis with pathological fracture
0.445 0.555 0.000
M80.4 Drug-induced osteoporosis with pathological fracture
0.445 0.555 0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture
0.445 0.555 0.000
M80.2 Osteoporosis of disuse with pathological fracture
0.445 0.555 0.000
E83.3 Disorders of phosphorus metabolism
0.000 0.555 0.445
E26.0 Primary hyperaldosteronism
0.000 0.558 0.442
M93 Other osteochondropathies
0.441 0.559 0.000
M48 Other spondylopathies
0.440 0.560 0.000
M85.6 Other cyst of bone
0.439 0.561 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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