TreeWAS – Variant ID: rs9378109

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	0.000	0.000	1.000
K90.0 Coeliac disease	0.000	0.000	1.000
L40.9 Psoriasis, unspecified	1.000	0.000	0.000
L40.5 Arthropathic psoriasis	1.000	0.000	0.000
L40 Psoriasis	1.000	0.000	0.000
E00-E07 Disorders of thyroid gland	0.000	0.000	1.000
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.000	1.000
E10 Insulin-dependent diabetes mellitus	0.000	0.000	1.000
E10.9 Without complications	0.000	0.000	1.000
E03 Other hypothyroidism	0.000	0.000	1.000
E05.9 Thyrotoxicosis, unspecified	0.000	0.000	1.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.001	0.999
E10-E14 Diabetes mellitus	0.000	0.002	0.998
E50-E64 Other nutritional deficiencies	0.000	0.010	0.990
L40.0 Psoriasis vulgaris	0.988	0.012	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.985	0.015	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.018	0.982
E53 Deficiency of other B group vitamins	0.000	0.019	0.981
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.979	0.021	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.977	0.023	0.000
E53.8 Deficiency of other specified B group vitamins	0.000	0.025	0.975
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.963	0.037	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.948	0.052	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.939	0.061	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.938	0.062	0.000
E10.4 With neurological complications	0.000	0.067	0.933
T39.1 4-Aminophenol derivatives	0.924	0.076	0.000
T43.2 Other and unspecified antidepressants	0.910	0.090	0.000
E10.5 With peripheral circulatory complications	0.000	0.094	0.906
L40.1 Generalised pustular psoriasis	0.895	0.105	0.000
T42.4 Benzodiazepines	0.891	0.109	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.885	0.115	0.000
E10.3 With ophthalmic complications	0.000	0.121	0.879
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.879	0.121	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.873	0.127	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.845	0.155	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.842	0.158	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.175	0.825
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.817	0.183	0.000
E10.2 With renal complications	0.000	0.185	0.815
T43.6 Psychostimulants with abuse potential	0.813	0.187	0.000
E06 Thyroiditis	0.000	0.190	0.810
E55 Vitamin D deficiency	0.000	0.193	0.807
T43.4 Butyrophenone and thioxanthene neuroleptics	0.804	0.196	0.000
L40.8 Other psoriasis	0.799	0.201	0.000
E10.6 With other specified complications	0.000	0.217	0.783
T50.6 Antidotes and chelating agents, not elsewhere classified	0.776	0.224	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.771	0.229	0.000
E04 Other non-toxic goitre	0.000	0.234	0.766
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.758	0.242	0.000
E10.0 With coma	0.000	0.246	0.754
E10.8 With unspecified complications	0.000	0.253	0.747
T39.0 Salicylates	0.738	0.262	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.735	0.265	0.000
E04.9 Non-toxic goitre, unspecified	0.000	0.268	0.732
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.718	0.282	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.717	0.283	0.000
L40.4 Guttate psoriasis	0.717	0.283	0.000
L40.3 Pustulosis palmaris et plantaris	0.717	0.283	0.000
L40.2 Acrodermatitis continua	0.717	0.283	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.283	0.717
E00 Congenital iodine-deficiency syndrome	0.000	0.283	0.717
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.283	0.717
E05.8 Other thyrotoxicosis	0.000	0.283	0.717
E05.5 Thyroid crisis or storm	0.000	0.283	0.717
E05.4 Thyrotoxicosis factitia	0.000	0.283	0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.283	0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.283	0.717
E10.7 With multiple complications	0.000	0.283	0.717
E03.5 Myxoedema coma	0.000	0.283	0.717
E03.4 Atrophy of thyroid (acquired)	0.000	0.283	0.717
E03.3 Postinfectious hypothyroidism	0.000	0.283	0.717
E03.1 Congenital hypothyroidism without goitre	0.000	0.283	0.717
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.283	0.717
E12 Malnutrition-related diabetes mellitus	0.000	0.284	0.715
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.290	0.710
E63 Other nutritional deficiencies	0.000	0.290	0.710
E56 Other vitamin deficiencies	0.000	0.290	0.710
E51 Thiamine deficiency	0.000	0.290	0.710
E50 Vitamin A deficiency	0.000	0.290	0.710
E60 Dietary zinc deficiency	0.000	0.290	0.710
E59 Dietary selenium deficiency	0.000	0.290	0.710
E58 Dietary calcium deficiency	0.000	0.290	0.710
E54 Ascorbic acid deficiency	0.000	0.290	0.710
E52 Niacin deficiency [pellagra]	0.000	0.290	0.710
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.290	0.710
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.707	0.293	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.707	0.293	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.707	0.293	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.707	0.293	0.000
E07 Other disorders of thyroid	0.000	0.294	0.706
E53.9 Vitamin B deficiency, unspecified	0.000	0.297	0.703
E53.1 Pyridoxine deficiency	0.000	0.297	0.703
E53.0 Riboflavin deficiency	0.000	0.297	0.703
T36 Poisoning by systemic antibiotics	0.703	0.297	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.702	0.298	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.702	0.298	0.000
T42.3 Barbiturates	0.702	0.298	0.000
T42.2 Succinimides and oxazolidinediones	0.702	0.298	0.000
T42.0 Hydantoin derivatives	0.702	0.298	0.000
E06.3 Autoimmune thyroiditis	0.000	0.298	0.701
T43.9 Psychotropic drug, unspecified	0.700	0.299	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.700	0.299	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.700	0.299	0.000
E16 Other disorders of pancreatic internal secretion	0.000	0.300	0.700
T47.0 Histamine H(2)-receptor antagonists	0.686	0.314	0.000
E61 Deficiency of other nutrient elements	0.000	0.316	0.684
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.679	0.321	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.679	0.321	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.679	0.321	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.679	0.321	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.679	0.321	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.679	0.321	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.679	0.321	0.000
T44.0 Anticholinesterase agents	0.679	0.321	0.000
E55.9 Vitamin D deficiency, unspecified	0.000	0.324	0.676
T50.8 Diagnostic agents	0.673	0.327	0.000
T50.7 Analeptics and opioid receptor antagonists	0.673	0.327	0.000
T50.5 Appetite depressants	0.673	0.327	0.000
T50.4 Drugs affecting uric acid metabolism	0.673	0.327	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.673	0.327	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.673	0.327	0.000
T50.1 Loop [high-ceiling] diuretics	0.673	0.327	0.000
T50.0 Mineralocorticoids and their antagonists	0.673	0.327	0.000
T39.4 Antirheumatics, not elsewhere classified	0.672	0.328	0.000
T39.2 Pyrazolone derivatives	0.672	0.328	0.000
E10.1 With ketoacidosis	0.000	0.328	0.672
T42.1 Iminostilbenes	0.670	0.330	0.000
T45.0 Antiallergic and antiemetic drugs	0.650	0.350	0.000
E03.8 Other specified hypothyroidism	0.000	0.355	0.645
E13 Other specified diabetes mellitus	0.000	0.365	0.634
J45.9 Asthma, unspecified	0.000	0.381	0.619
T46.4 Angiotensin-converting-enzyme inhibitors	0.615	0.385	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.603	0.396	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.600	0.400	0.000
E15 Nondiabetic hypoglycaemic coma	0.000	0.408	0.591
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.586	0.414	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.586	0.414	0.000
T47.7 Emetics	0.586	0.414	0.000
T47.6 Antidiarrhoeal drugs	0.586	0.414	0.000
T47.5 Digestants	0.586	0.414	0.000
T47.4 Other laxatives	0.586	0.414	0.000
T47.3 Saline and osmotic laxatives	0.586	0.414	0.000
T47.2 Stimulant laxatives	0.586	0.414	0.000
E16.2 Hypoglycaemia, unspecified	0.000	0.414	0.586
E06.5 Other chronic thyroiditis	0.000	0.419	0.581
E06.4 Drug-induced thyroiditis	0.000	0.419	0.581
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.419	0.581
E06.1 Subacute thyroiditis	0.000	0.419	0.581
E06.0 Acute thyroiditis	0.000	0.419	0.581
E55.0 Rickets, active	0.000	0.421	0.578
E40-E46 Malnutrition	0.000	0.428	0.572
T46.1 Calcium-channel blockers	0.571	0.429	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.566	0.434	0.000
E07.9 Disorder of thyroid, unspecified	0.000	0.438	0.562
E65-E68 Obesity and other hyperalimentation	0.000	0.439	0.561
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.440	0.560
T38.1 Thyroid hormones and substitutes	0.560	0.440	0.000
J45 Asthma	0.000	0.445	0.555
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.552	0.447	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.552	0.447	0.000
T46.7 Peripheral vasodilators	0.552	0.447	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.552	0.447	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.552	0.447	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.552	0.447	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.552	0.447	0.000
E04.8 Other specified non-toxic goitre	0.000	0.451	0.549
J45.0 Predominantly allergic asthma	0.000	0.454	0.546
T45.9 Primarily systemic and haematological agent, unspecified	0.544	0.456	0.000
T45.8 Other primarily systemic and haematological agents	0.544	0.456	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.544	0.456	0.000
T45.6 Fibrinolysis-affecting drugs	0.544	0.456	0.000
T45.4 Iron and its compounds	0.544	0.456	0.000
T45.3 Enzymes, not elsewhere classified	0.544	0.456	0.000
T45.2 Vitamins, not elsewhere classified	0.544	0.456	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.534	0.465	0.000
E16.1 Other hypoglycaemia	0.000	0.469	0.531
T38.9 Other and unspecified hormone antagonists	0.527	0.473	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.527	0.473	0.000
T38.7 Androgens and anabolic congeners	0.527	0.473	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.527	0.473	0.000
T38.5 Other oestrogens and progestogens	0.527	0.473	0.000
T38.4 Oral contraceptives	0.527	0.473	0.000
T38.2 Antithyroid drugs	0.527	0.473	0.000
T38.0 Glucocorticoids and synthetic analogues	0.527	0.473	0.000
E06.9 Thyroiditis, unspecified	0.000	0.476	0.524
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.521	0.479	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.479	0.521
E04.0 Non-toxic diffuse goitre	0.000	0.480	0.520
T45.1 Antineoplastic and immunosuppressive drugs	0.518	0.482	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.486	0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.486	0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.486	0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.486	0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.486	0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.486	0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.486	0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.486	0.514
K90 Intestinal malabsorption	0.000	0.487	0.513
E12.9 Without complications	0.000	0.487	0.513
E12.8 With unspecified complications	0.000	0.487	0.513
E12.7 With multiple complications	0.000	0.487	0.513
E12.6 With other specified complications	0.000	0.487	0.513
E12.5 With peripheral circulatory complications	0.000	0.487	0.513
E12.4 With neurological complications	0.000	0.487	0.513
E12.3 With ophthalmic complications	0.000	0.487	0.513
E12.2 With renal complications	0.000	0.487	0.513
E12.1 With ketoacidosis	0.000	0.487	0.513
E12.0 With coma	0.000	0.487	0.513
E50.9 Vitamin A deficiency, unspecified	0.000	0.491	0.509
E50.8 Other manifestations of vitamin A deficiency	0.000	0.491	0.509
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.491	0.509
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.491	0.509
E50.5 Vitamin A deficiency with night blindness	0.000	0.491	0.509
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.491	0.509
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.491	0.509
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.491	0.509
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.491	0.509
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.491	0.509
E51.9 Thiamine deficiency, unspecified	0.000	0.491	0.509
E51.8 Other manifestations of thiamine deficiency	0.000	0.491	0.509
E51.2 Wernicke's encephalopathy	0.000	0.491	0.509
E51.1 Beriberi	0.000	0.491	0.509
E56.9 Vitamin deficiency, unspecified	0.000	0.491	0.509
E56.8 Deficiency of other vitamins	0.000	0.491	0.509
E56.1 Deficiency of vitamin K	0.000	0.491	0.509
E56.0 Deficiency of vitamin E	0.000	0.491	0.509
E63.9 Nutritional deficiency, unspecified	0.000	0.491	0.509
E63.8 Other specified nutritional deficiencies	0.000	0.491	0.509
E63.1 Imbalance of constituents of food intake	0.000	0.491	0.509
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.491	0.509
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.491	0.509
E64.8 Sequelae of other nutritional deficiencies	0.000	0.491	0.509
E64.3 Sequelae of rickets	0.000	0.491	0.509
E64.2 Sequelae of vitamin C deficiency	0.000	0.491	0.509
E64.1 Sequelae of vitamin A deficiency	0.000	0.491	0.509
E64.0 Sequelae of protein-energy malnutrition	0.000	0.491	0.509
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.507	0.493	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.507	0.493	0.000
T37.5 Antiviral drugs	0.507	0.493	0.000
T37.4 Anthelminthics	0.507	0.493	0.000
T37.3 Other antiprotozoal drugs	0.507	0.493	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.507	0.493	0.000
T37.1 Antimycobacterial drugs	0.507	0.493	0.000
T37.0 Sulphonamides	0.507	0.493	0.000
T41.5 Therapeutic gases	0.507	0.493	0.000
T41.4 Anaesthetic, unspecified	0.507	0.493	0.000
T41.3 Local anaesthetics	0.507	0.493	0.000
T41.2 Other and unspecified general anaesthetics	0.507	0.493	0.000
T41.1 Intravenous anaesthetics	0.507	0.493	0.000
T41.0 Inhaled anaesthetics	0.507	0.493	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.507	0.493	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.507	0.493	0.000
T48.5 Anti-common-cold drugs	0.507	0.493	0.000
T48.4 Expectorants	0.507	0.493	0.000
T48.3 Antitussives	0.507	0.493	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.507	0.493	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.507	0.493	0.000
T48.0 Oxytocic drugs	0.507	0.493	0.000
T49.9 Topical agent, unspecified	0.507	0.493	0.000
T49.8 Other topical agents	0.507	0.493	0.000
T49.7 Dental drugs, topically applied	0.507	0.493	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.507	0.493	0.000
T49.5 Ophthalmological drugs and preparations	0.507	0.493	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.507	0.493	0.000
T49.3 Emollients, demulcents and protectants	0.507	0.493	0.000
T49.2 Local astringents and local detergents	0.507	0.493	0.000
T49.1 Antipruritics	0.507	0.493	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.507	0.493	0.000
E07.1 Dyshormogenetic goitre	0.000	0.494	0.506
E07.0 Hypersecretion of calcitonin	0.000	0.494	0.506
T36.9 Systemic antibiotic, unspecified	0.504	0.496	0.000
T36.8 Other systemic antibiotics	0.504	0.496	0.000
T36.7 Antifungal antibiotics, systemically used	0.504	0.496	0.000
T36.6 Rifamycins	0.504	0.496	0.000
T36.5 Aminoglycosides	0.504	0.496	0.000
T36.4 Tetracyclines	0.504	0.496	0.000
T36.3 Macrolides	0.504	0.496	0.000
T36.2 Chloramphenicol group	0.504	0.496	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.504	0.496	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.498	0.502
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.498	0.502
E16.4 Abnormal secretion of gastrin	0.000	0.498	0.502
E16.3 Increased secretion of glucagon	0.000	0.498	0.502
T36.0 Penicillins	0.500	0.500	0.000
E61.9 Deficiency of nutrient element, unspecified	0.000	0.510	0.490
E61.8 Deficiency of other specified nutrient elements	0.000	0.510	0.490
E61.7 Deficiency of multiple nutrient elements	0.000	0.510	0.490
E61.6 Vanadium deficiency	0.000	0.510	0.490
E61.5 Molybdenum deficiency	0.000	0.510	0.490
E61.4 Chromium deficiency	0.000	0.510	0.490
E61.3 Manganese deficiency	0.000	0.510	0.490
E61.0 Copper deficiency	0.000	0.510	0.490
E61.2 Magnesium deficiency	0.000	0.510	0.490
T45.5 Anticoagulants	0.470	0.530	0.000
E61.1 Iron deficiency	0.000	0.536	0.464
E13.8 With unspecified complications	0.000	0.545	0.455
E13.7 With multiple complications	0.000	0.545	0.455
E13.6 With other specified complications	0.000	0.545	0.455
E13.5 With peripheral circulatory complications	0.000	0.545	0.455
E13.4 With neurological complications	0.000	0.545	0.455
E13.3 With ophthalmic complications	0.000	0.545	0.455
E13.2 With renal complications	0.000	0.545	0.455
E13.1 With ketoacidosis	0.000	0.545	0.455
E13.0 With coma	0.000	0.545	0.455
K90.9 Intestinal malabsorption, unspecified	0.000	0.562	0.438
M07.30 Other psoriatic arthropathies (Multiple sites)	0.429	0.571	0.000
M07.3 Other psoriatic arthropathies	0.421	0.579	0.000
E07.8 Other specified disorders of thyroid	0.000	0.587	0.413
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.589	0.410
E45 Retarded development following protein-energy malnutrition	0.000	0.589	0.410
E43 Unspecified severe protein-energy malnutrition	0.000	0.589	0.410
E42 Marasmic kwashiorkor	0.000	0.589	0.410
E41 Nutritional marasmus	0.000	0.589	0.410
E40 Kwashiorkor	0.000	0.589	0.410
M07.39 Other psoriatic arthropathies (Site unspecified)	0.410	0.590	0.000
E67 Other hyperalimentation	0.000	0.597	0.402
E68 Sequelae of hyperalimentation	0.000	0.597	0.402
J45.8 Mixed asthma	0.000	0.602	0.398
E20-E35 Disorders of other endocrine glands	0.000	0.622	0.378
E13.9 Without complications	0.000	0.626	0.374
K90.3 Pancreatic steatorrhoea	0.000	0.632	0.368
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.632	0.368
K90.1 Tropical sprue	0.000	0.632	0.368
M07.36 Other psoriatic arthropathies (Lower leg)	0.354	0.646	0.000
E04.1 Non-toxic single thyroid nodule	0.000	0.649	0.351
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.650	0.350
E66 Obesity	0.000	0.653	0.347
M07.34 Other psoriatic arthropathies (Hand)	0.346	0.654	0.000
J45.1 Nonallergic asthma	0.000	0.657	0.343
E27 Other disorders of adrenal gland	0.000	0.660	0.340
K90.8 Other intestinal malabsorption	0.000	0.667	0.333
E65 Localised adiposity	0.000	0.672	0.328
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.323	0.676	0.000
E27.1 Primary adrenocortical insufficiency	0.000	0.678	0.322
E14 Unspecified diabetes mellitus	0.000	0.688	0.312
E66.8 Other obesity	0.000	0.696	0.304
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.303	0.696	0.001
M07.38 Other psoriatic arthropathies (Other)	0.302	0.698	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.302	0.698	0.000
M07.33 Other psoriatic arthropathies (Forearm)	0.302	0.698	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.302	0.698	0.000
M07.31 Other psoriatic arthropathies (Shoulder region)	0.302	0.698	0.000
E44.1 Mild protein-energy malnutrition	0.000	0.705	0.294
E44.0 Moderate protein-energy malnutrition	0.000	0.705	0.294
E67.8 Other specified hyperalimentation	0.000	0.711	0.289
E67.3 Hypervitaminosis D	0.000	0.711	0.289
E67.2 Megavitamin-B6 syndrome	0.000	0.711	0.289
E67.1 Hypercarotenaemia	0.000	0.711	0.289
E67.0 Hypervitaminosis A	0.000	0.711	0.289
E04.2 Non-toxic multinodular goitre	0.000	0.718	0.282
E27.8 Other specified disorders of adrenal gland	0.000	0.719	0.281
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.729	0.271
E32 Diseases of thymus	0.000	0.729	0.271
E31 Polyglandular dysfunction	0.000	0.729	0.271
E30 Disorders of puberty, not elsewhere classified	0.000	0.729	0.271
E25 Adrenogenital disorders	0.000	0.729	0.271
E46 Unspecified protein-energy malnutrition	0.001	0.733	0.266
E29 Testicular dysfunction	0.000	0.733	0.267
E24 Cushing's syndrome	0.000	0.737	0.263
E34 Other endocrine disorders	0.000	0.738	0.262
E22 Hyperfunction of pituitary gland	0.000	0.741	0.259
E66.2 Extreme obesity with alveolar hypoventilation	0.000	0.741	0.259
E28 Ovarian dysfunction	0.000	0.748	0.252
E66.1 Drug-induced obesity	0.000	0.751	0.249
E27.5 Adrenomedullary hyperfunction	0.000	0.756	0.244
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.756	0.244
E27.0 Other adrenocortical overactivity	0.000	0.756	0.244
E20 Hypoparathyroidism	0.000	0.758	0.241
E27.2 Addisonian crisis	0.000	0.761	0.239
E14.4 With neurological complications	0.000	0.769	0.231
E66.0 Obesity due to excess calories	0.000	0.773	0.227
L40-L45 Papulosquamous disorders	0.224	0.776	0.000
E14.8 With unspecified complications	0.000	0.776	0.224
E14.7 With multiple complications	0.000	0.776	0.224
E14.6 With other specified complications	0.000	0.776	0.224
E14.2 Withrenal complications	0.000	0.776	0.224
E14.0 With coma	0.000	0.776	0.224
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.222	0.777	0.001
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.779	0.221
E22.1 Hyperprolactinaemia	0.000	0.780	0.220
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.218	0.782	0.001
T40.8 Lysergide [LSD]	0.218	0.782	0.001
T40.7 Cannabis (derivatives)	0.218	0.782	0.001
T40.5 Cocaine	0.218	0.782	0.001
T40.3 Methadone	0.218	0.782	0.001
T40.1 Heroin	0.218	0.782	0.001
T40.0 Opium	0.218	0.782	0.001
E26 Hyperaldosteronism	0.000	0.783	0.216
E14.3 With ophthalmic complications	0.000	0.785	0.215
E28.3 Primary ovarian failure	0.000	0.790	0.209
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.803	0.197
E24.9 Cushing's syndrome, unspecified	0.000	0.803	0.196
E25.9 Adrenogenital disorder, unspecified	0.000	0.806	0.194
E25.8 Other adrenogenital disorders	0.000	0.806	0.194
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.806	0.194
E30.9 Disorder of puberty, unspecified	0.000	0.806	0.194
E30.8 Other disorders of puberty	0.000	0.806	0.194
E30.1 Precocious puberty	0.000	0.806	0.194
E30.0 Delayed puberty	0.000	0.806	0.194
E31.9 Polyglandular dysfunction, unspecified	0.000	0.806	0.194
E31.8 Other polyglandular dysfunction	0.000	0.806	0.194
E31.1 Polyglandular hyperfunction	0.000	0.806	0.194
E31.0 Autoimmune polyglandular failure	0.000	0.806	0.194
E32.9 Disease of thymus, unspecified	0.000	0.806	0.194
E32.8 Other diseases of thymus	0.000	0.806	0.194
E32.1 Abscess of thymus	0.000	0.806	0.194
E32.0 Persistent hyperplasia of thymus	0.000	0.806	0.194
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.806	0.194
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.806	0.194
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.806	0.194
T40.6 Other and unspecified narcotics	0.193	0.807	0.001
E34.0 Carcinoid syndrome	0.000	0.808	0.192
E29.9 Testicular dysfunction, unspecified	0.000	0.808	0.191
E29.8 Other testicular dysfunction	0.000	0.808	0.191
E29.0 Testicular hyperfunction	0.000	0.808	0.191
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.189	0.811	0.000
E14.1 With ketoacidosis	0.000	0.811	0.189
E24.8 Other Cushing's syndrome	0.000	0.811	0.189
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.811	0.189
E24.3 Ectopic ACTH syndrome	0.000	0.811	0.189
E24.1 Nelson's syndrome	0.000	0.811	0.189
E24.0 Pituitary-dependent Cushing's disease	0.000	0.811	0.189
E14.5 With peripheral circulatory complications	0.000	0.812	0.188
E34.8 Other specified endocrine disorders	0.000	0.812	0.188
E34.5 Androgen resistance syndrome	0.000	0.812	0.188
E34.4 Constitutional tall stature	0.000	0.812	0.188
E34.3 Short stature, not elsewhere classified	0.000	0.812	0.188
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.812	0.188
E34.1 Other hypersecretion of intestinal hormones	0.000	0.812	0.188
E29.1 Testicular hypofunction	0.000	0.812	0.187
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.814	0.186
E22.8 Other hyperfunction of pituitary gland	0.000	0.814	0.186
M07 Psoriatic and enteropathic arthropathies	0.183	0.817	0.000
E28.9 Ovarian dysfunction, unspecified	0.000	0.819	0.181
E28.8 Other ovarian dysfunction	0.000	0.819	0.181
E28.1 Androgen excess	0.000	0.819	0.181
E28.0 Oestrogen excess	0.000	0.819	0.181
T20-T25 Burns and corrosions of external body surface, specified by site	0.180	0.820	0.000
S80-S89 Injuries to the knee and lower leg	0.179	0.821	0.000
S82 Fracture of lower leg, including ankle	0.176	0.824	0.000
E34.9 Endocrine disorder, unspecified	0.000	0.825	0.175
E20.8 Other hypoparathyroidism	0.000	0.826	0.173
E20.1 Pseudohypoparathyroidism	0.000	0.826	0.173
E20.0 Idiopathic hypoparathyroidism	0.000	0.826	0.173
E24.2 Drug-induced Cushing's syndrome	0.000	0.828	0.171
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.832	0.168
S10-S19 Injuries to the neck	0.166	0.834	0.000
S82.1 Fracture of upper end of tibia	0.166	0.834	0.000
T40.4 Other synthetic narcotics	0.165	0.834	0.001
S82.5 Fracture of medial malleolus	0.165	0.834	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.161	0.839	0.000
L44 Other papulosquamous disorders	0.161	0.839	0.000
L41 Parapsoriasis	0.161	0.839	0.000
L45 Papulosquamous disorders in diseases classified elsewhere	0.161	0.839	0.000
S82.10 Fracture of upper end of tibia (closed)	0.160	0.840	0.000
E27.9 Disorder of adrenal gland, unspecified	0.000	0.841	0.159
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.159	0.841	0.000
S82.50 Fracture of medial malleolus (closed)	0.158	0.842	0.000
E26.9 Hyperaldosteronism, unspecified	0.000	0.844	0.155
E26.8 Other hyperaldosteronism	0.000	0.844	0.155
E26.1 Secondary hyperaldosteronism	0.000	0.844	0.155
T15-T19 Effects of foreign body entering through natural orifice	0.154	0.846	0.000
T66-T78 Other and unspecified effects of external causes	0.153	0.847	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.151	0.849	0.000
T25 Burn and corrosion of ankle and foot	0.151	0.849	0.000
E70-E90 Metabolic disorders	0.000	0.850	0.150
E21.3 Hyperparathyroidism, unspecified	0.000	0.851	0.149
S82.0 Fracture of patella	0.149	0.851	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.148	0.852	0.000
S11 Open wound of neck	0.145	0.855	0.000
S82.4 Fracture of fibula alone	0.145	0.855	0.000
E20.9 Hypoparathyroidism, unspecified	0.000	0.856	0.144
T21 Burn and corrosion of trunk	0.143	0.857	0.000
S10 Superficial injury of neck	0.142	0.858	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.000	0.858	0.142
E21.4 Other specified disorders of parathyroid gland	0.000	0.858	0.142
E21.2 Other hyperparathyroidism	0.000	0.858	0.142
T20 Burn and corrosion of head and neck	0.139	0.861	0.000
L42 Pityriasis rosea	0.138	0.861	0.000
S81 Open wound of lower leg	0.138	0.862	0.000
T00-T07 Injuries involving multiple body regions	0.138	0.862	0.000
S82.6 Fracture of lateral malleolus	0.138	0.862	0.000
S86 Injury of muscle and tendon at lower leg level	0.137	0.863	0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.136	0.864	0.000
T33-T35 Frostbite	0.136	0.864	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.136	0.864	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.000	0.865	0.134
T22.2 Burn of second degree of shoulder and upper limb, except wrist and hand	0.134	0.866	0.000
S30 Superficial injury of abdomen, lower back and pelvis	0.134	0.866	0.000
T11 Other injuries of upper limb, level unspecified	0.134	0.866	0.000
T18 Foreign body in alimentary tract	0.133	0.867	0.000
E22.0 Acromegaly and pituitary gigantism	0.000	0.867	0.133
E23 Hypofunction and other disorders of pituitary gland	0.000	0.867	0.133
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.133	0.867	0.000
T09 Other injuries of spine and trunk, level unspecified	0.132	0.868	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.000	0.868	0.132
M07.6 Other enteropathic arthropathies	0.131	0.868	0.000
M07.5 Arthropathy in ulcerative colitis	0.131	0.868	0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.131	0.868	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations