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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs9380236
log Bayes Factor = 10.6286
Chromosome 6   position 31,254,664  (GRCh37) Explore rs9380236 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M45.X9 Ankylosing spondylitis (Site unspecified)
1.000 0.000 0.000
E03.9 Hypothyroidism, unspecified
0.000 0.001 0.999
E00-E07 Disorders of thyroid gland
0.000 0.002 0.998
E03 Other hypothyroidism
0.000 0.002 0.998
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.004 0.996
E10 Insulin-dependent diabetes mellitus
0.000 0.004 0.996
E10-E14 Diabetes mellitus
0.000 0.005 0.995
M45 Ankylosing spondylitis
0.992 0.008 0.000
M06.9 Rheumatoid arthritis, unspecified
0.992 0.008 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.992 0.008 0.000
M06 Other rheumatoid arthritis
0.989 0.011 0.000
E10.9 Without complications
0.000 0.014 0.986
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.973 0.027 0.000
M05-M14 Inflammatory polyarthropathies
0.971 0.029 0.000
E10.1 With ketoacidosis
0.000 0.046 0.954
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.056 0.944
M07 Psoriatic and enteropathic arthropathies
0.943 0.057 0.000
M06.0 Seronegative rheumatoid arthritis
0.930 0.070 0.000
E10.3 With ophthalmic complications
0.000 0.073 0.927
M07.3 Other psoriatic arthropathies
0.924 0.076 0.000
M45-M49 Spondylopathies
0.913 0.087 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.902 0.098 0.000
E50-E64 Other nutritional deficiencies
0.000 0.107 0.893
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.888 0.112 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.121 0.879
M07.30 Other psoriatic arthropathies (Multiple sites)
0.875 0.125 0.000
E10.4 With neurological complications
0.000 0.131 0.869
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.868 0.132 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.852 0.148 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.843 0.157 0.000
E04 Other non-toxic goitre
0.000 0.178 0.822
E55 Vitamin D deficiency
0.000 0.179 0.821
E20-E35 Disorders of other endocrine glands
0.000 0.180 0.820
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.814 0.186 0.000
E06 Thyroiditis
0.000 0.188 0.812
M07.39 Other psoriatic arthropathies (Site unspecified)
0.802 0.198 0.000
E10.5 With peripheral circulatory complications
0.000 0.202 0.798
E05.9 Thyrotoxicosis, unspecified
0.000 0.217 0.783
M14 Arthropathies in other diseases classified elsewhere
0.783 0.217 0.000
M06.4 Inflammatory polyarthropathy
0.780 0.220 0.000
E70-E90 Metabolic disorders
0.000 0.223 0.777
E55.9 Vitamin D deficiency, unspecified
0.000 0.230 0.770
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.760 0.240 0.000
E13 Other specified diabetes mellitus
0.000 0.241 0.759
K90.0 Coeliac disease
0.000 0.241 0.759
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.755 0.245 0.000
M05 Seropositive rheumatoid arthritis
0.755 0.245 0.000
E07 Other disorders of thyroid
0.000 0.246 0.754
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.752 0.248 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.750 0.250 0.000
M06.3 Rheumatoid nodule
0.735 0.264 0.000
E40-E46 Malnutrition
0.000 0.265 0.735
E27 Other disorders of adrenal gland
0.000 0.277 0.723
E04.2 Non-toxic multinodular goitre
0.000 0.282 0.718
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.284 0.716
E00 Congenital iodine-deficiency syndrome
0.000 0.284 0.716
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.284 0.716
E03.5 Myxoedema coma
0.000 0.284 0.716
E03.4 Atrophy of thyroid (acquired)
0.000 0.284 0.716
E03.3 Postinfectious hypothyroidism
0.000 0.284 0.716
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.284 0.716
E03.1 Congenital hypothyroidism without goitre
0.000 0.284 0.716
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.284 0.716
E10.8 With unspecified complications
0.000 0.286 0.714
E10.7 With multiple complications
0.000 0.286 0.714
E10.0 With coma
0.000 0.286 0.714
E12 Malnutrition-related diabetes mellitus
0.000 0.286 0.713
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.711 0.288 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.711 0.288 0.000
M45.X6 Ankylosing spondylitis (Lumbar region)
0.711 0.288 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.711 0.288 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.711 0.288 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.711 0.288 0.000
M45.X2 Ankylosing spondylitis (Cervical region)
0.711 0.288 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.711 0.288 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.711 0.289 0.000
M06.8 Other specified rheumatoid arthritis
0.709 0.291 0.000
M06.2 Rheumatoid bursitis
0.709 0.291 0.000
M06.1 Adult-onset Still's disease
0.709 0.291 0.000
M00-M03 Infectious arthropathies
0.706 0.294 0.000
M12 Other specific arthropathies
0.696 0.304 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.696 0.304 0.000
M08 Juvenile arthritis
0.696 0.304 0.000
E10.2 With renal complications
0.000 0.308 0.692
E22 Hyperfunction of pituitary gland
0.000 0.311 0.689
E14 Unspecified diabetes mellitus
0.000 0.313 0.687
E27.1 Primary adrenocortical insufficiency
0.000 0.313 0.687
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.319 0.681
M60-M63 Disorders of muscles
0.680 0.319 0.000
E05.8 Other thyrotoxicosis
0.000 0.323 0.677
E05.5 Thyroid crisis or storm
0.000 0.323 0.677
E05.4 Thyrotoxicosis factitia
0.000 0.323 0.677
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.323 0.677
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.323 0.677
M07.6 Other enteropathic arthropathies
0.676 0.324 0.000
M07.5 Arthropathy in ulcerative colitis
0.676 0.324 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.676 0.324 0.000
M07.2 Psoriatic spondylitis
0.676 0.324 0.000
M07.1 Arthritis mutilans
0.676 0.324 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.676 0.324 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.325 0.675
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.325 0.675
M11 Other crystal arthropathies
0.671 0.328 0.000
M06.08 Seronegative rheumatoid arthritis (Other)
0.667 0.333 0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.667 0.333 0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.667 0.333 0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.667 0.333 0.000
M06.04 Seronegative rheumatoid arthritis (Hand)
0.667 0.333 0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.667 0.333 0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.667 0.333 0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.667 0.333 0.000
E53 Deficiency of other B group vitamins
0.000 0.335 0.665
E06.3 Autoimmune thyroiditis
0.000 0.336 0.664
M07.38 Other psoriatic arthropathies (Other)
0.662 0.338 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.662 0.338 0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.662 0.338 0.000
M07.34 Other psoriatic arthropathies (Hand)
0.662 0.338 0.000
M07.33 Other psoriatic arthropathies (Forearm)
0.662 0.338 0.000
M07.32 Other psoriatic arthropathies (Upper arm)
0.662 0.338 0.000
M07.31 Other psoriatic arthropathies (Shoulder region)
0.662 0.338 0.000
E03.8 Other specified hypothyroidism
0.000 0.340 0.660
M80-M85 Disorders of bone density and structure
0.659 0.341 0.000
E04.1 Non-toxic single thyroid nodule
0.000 0.341 0.659
M49 Spondylopathies in diseases classified elsewhere
0.655 0.345 0.000
M14.6 Neuropathic arthropathy
0.647 0.352 0.000
E88 Other metabolic disorders
0.000 0.355 0.645
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.359 0.640
E63 Other nutritional deficiencies
0.000 0.359 0.640
E56 Other vitamin deficiencies
0.000 0.359 0.640
E51 Thiamine deficiency
0.000 0.359 0.640
E50 Vitamin A deficiency
0.000 0.359 0.640
E60 Dietary zinc deficiency
0.000 0.359 0.640
E59 Dietary selenium deficiency
0.000 0.359 0.640
E58 Dietary calcium deficiency
0.000 0.359 0.640
E54 Ascorbic acid deficiency
0.000 0.359 0.640
E52 Niacin deficiency [pellagra]
0.000 0.359 0.640
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.364 0.636
M40-M43 Deforming dorsopathies
0.634 0.366 0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.631 0.369 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.369 0.630
E10.6 With other specified complications
0.000 0.372 0.628
M86-M90 Other osteopathies
0.622 0.378 0.000
E26 Hyperaldosteronism
0.000 0.379 0.621
M91-M94 Chondropathies
0.620 0.380 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.617 0.383 0.000
E87.6 Hypokalaemia
0.000 0.389 0.611
E61 Deficiency of other nutrient elements
0.000 0.393 0.607
M46 Other inflammatory spondylopathies
0.605 0.394 0.000
E06.9 Thyroiditis, unspecified
0.000 0.395 0.605
E07.9 Disorder of thyroid, unspecified
0.000 0.399 0.601
E21.0 Primary hyperparathyroidism
0.000 0.400 0.600
M05.9 Seropositive rheumatoid arthritis, unspecified
0.600 0.400 0.000
E04.0 Non-toxic diffuse goitre
0.000 0.405 0.595
E73 Lactose intolerance
0.000 0.407 0.593
E86 Volume depletion
0.000 0.409 0.591
E04.8 Other specified non-toxic goitre
0.000 0.410 0.590
E13.9 Without complications
0.000 0.411 0.589
E55.0 Rickets, active
0.000 0.411 0.589
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.412 0.588
E32 Diseases of thymus
0.000 0.412 0.588
E31 Polyglandular dysfunction
0.000 0.412 0.588
E30 Disorders of puberty, not elsewhere classified
0.000 0.412 0.588
E25 Adrenogenital disorders
0.000 0.412 0.588
E83 Disorders of mineral metabolism
0.000 0.413 0.587
E06.5 Other chronic thyroiditis
0.000 0.418 0.582
E06.4 Drug-induced thyroiditis
0.000 0.418 0.582
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.418 0.582
E06.1 Subacute thyroiditis
0.000 0.418 0.582
E06.0 Acute thyroiditis
0.000 0.418 0.582
E85 Amyloidosis
0.000 0.419 0.581
M02 Reactive arthropathies
0.579 0.421 0.000
E20 Hypoparathyroidism
0.000 0.426 0.574
M80 Osteoporosis with pathological fracture
0.567 0.433 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.562 0.438 0.000
M14.8 Arthropathies in other specified diseases classified elsewhere
0.561 0.439 0.000
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.561 0.439 0.000
M14.4 Arthropathy in amyloidosis
0.561 0.439 0.000
M14.3 Lipoid dermatoarthritis
0.561 0.439 0.000
M14.2 Diabetic arthropathy
0.561 0.439 0.000
M14.1 Crystal arthropathy in other metabolic disorders
0.561 0.439 0.000
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.561 0.439 0.000
M06.48 Inflammatory polyarthropathy (Other)
0.559 0.441 0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.559 0.441 0.000
M06.46 Inflammatory polyarthropathy (Lower leg)
0.559 0.441 0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.559 0.441 0.000
M06.44 Inflammatory polyarthropathy (Hand)
0.559 0.441 0.000
M06.43 Inflammatory polyarthropathy (Forearm)
0.559 0.441 0.000
M06.42 Inflammatory polyarthropathy (Upper arm)
0.559 0.441 0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.559 0.441 0.000
E22.0 Acromegaly and pituitary gigantism
0.000 0.442 0.558
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.557 0.442 0.000
E84 Cystic fibrosis
0.000 0.443 0.557
E79 Disorders of purine and pyrimidine metabolism
0.000 0.443 0.557
E77 Disorders of glycoprotein metabolism
0.000 0.443 0.557
E76 Disorders of glycosaminoglycan metabolism
0.000 0.443 0.557
E72 Other disorders of amino-acid metabolism
0.000 0.443 0.557
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.443 0.557
E70 Disorders of aromatic amino-acid metabolism
0.000 0.443 0.557
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.443 0.557
M06.34 Rheumatoid nodule (Hand)
0.554 0.446 0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.449 0.551
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.449 0.551
E28 Ovarian dysfunction
0.000 0.450 0.550
E46 Unspecified protein-energy malnutrition
0.000 0.452 0.548
E74 Other disorders of carbohydrate metabolism
0.000 0.453 0.547
E34 Other endocrine disorders
0.000 0.453 0.547
M10 Gout
0.547 0.453 0.000
E13.8 With unspecified complications
0.000 0.456 0.544
E13.7 With multiple complications
0.000 0.456 0.544
E13.6 With other specified complications
0.000 0.456 0.544
E13.5 With peripheral circulatory complications
0.000 0.456 0.544
E13.4 With neurological complications
0.000 0.456 0.544
E13.3 With ophthalmic complications
0.000 0.456 0.544
E13.2 With renal complications
0.000 0.456 0.544
E13.1 With ketoacidosis
0.000 0.456 0.544
E13.0 With coma
0.000 0.456 0.544
M05.8 Other seropositive rheumatoid arthritis
0.541 0.459 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.541 0.459 0.000
M05.2 Rheumatoid vasculitis
0.541 0.459 0.000
M05.1 Rheumatoid lung disease
0.541 0.459 0.000
M05.0 Felty's syndrome
0.541 0.459 0.000
M20-M25 Other joint disorders
0.541 0.459 0.000
E07.1 Dyshormogenetic goitre
0.000 0.459 0.541
E07.0 Hypersecretion of calcitonin
0.000 0.459 0.541
E87.0 Hyperosmolality and hypernatraemia
0.000 0.463 0.537
E24 Cushing's syndrome
0.000 0.464 0.536
M06.39 Rheumatoid nodule (Site unspecified)
0.527 0.472 0.000
M06.38 Rheumatoid nodule (Other)
0.527 0.472 0.000
M06.37 Rheumatoid nodule (Ankle and foot)
0.527 0.472 0.000
M06.36 Rheumatoid nodule (Lower leg)
0.527 0.472 0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.527 0.472 0.000
M06.33 Rheumatoid nodule (Forearm)
0.527 0.472 0.000
M06.32 Rheumatoid nodule (Upper arm)
0.527 0.472 0.000
M06.31 Rheumatoid nodule (Shoulder region)
0.527 0.472 0.000
M06.30 Rheumatoid nodule (Multiple sites)
0.527 0.472 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.473 0.527
E45 Retarded development following protein-energy malnutrition
0.000 0.473 0.527
E43 Unspecified severe protein-energy malnutrition
0.000 0.473 0.527
E42 Marasmic kwashiorkor
0.000 0.473 0.527
E41 Nutritional marasmus
0.000 0.473 0.527
E40 Kwashiorkor
0.000 0.473 0.527
M50-M54 Other dorsopathies
0.523 0.477 0.000
M62 Other disorders of muscle
0.521 0.479 0.000
M85 Other disorders of bone density and structure
0.520 0.480 0.000
E14.9 Without complications
0.000 0.480 0.520
E27.5 Adrenomedullary hyperfunction
0.000 0.481 0.519
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.481 0.519
E27.2 Addisonian crisis
0.000 0.481 0.519
E27.0 Other adrenocortical overactivity
0.000 0.481 0.519
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.487 0.513
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.487 0.513
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.487 0.513
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.487 0.513
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.487 0.513
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.487 0.513
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.487 0.513
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.487 0.513
E12.9 Without complications
0.000 0.488 0.512
E12.8 With unspecified complications
0.000 0.488 0.512
E12.7 With multiple complications
0.000 0.488 0.512
E12.6 With other specified complications
0.000 0.488 0.512
E12.5 With peripheral circulatory complications
0.000 0.488 0.512
E12.4 With neurological complications
0.000 0.488 0.512
E12.3 With ophthalmic complications
0.000 0.488 0.512
E12.2 With renal complications
0.000 0.488 0.512
E12.1 With ketoacidosis
0.000 0.488 0.512
E12.0 With coma
0.000 0.488 0.512
E07.8 Other specified disorders of thyroid
0.000 0.491 0.509
M06.19 Adult-onset Still's disease (Site unspecified)
0.508 0.492 0.000
M06.18 Adult-onset Still's disease (Other)
0.508 0.492 0.000
M06.17 Adult-onset Still's disease (Ankle and foot)
0.508 0.492 0.000
M06.16 Adult-onset Still's disease (Lower leg)
0.508 0.492 0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.508 0.492 0.000
M06.14 Adult-onset Still's disease (Hand)
0.508 0.492 0.000
M06.13 Adult-onset Still's disease (Forearm)
0.508 0.492 0.000
M06.12 Adult-onset Still's disease (Upper arm)
0.508 0.492 0.000
M06.11 Adult-onset Still's disease (Shoulder region)
0.508 0.492 0.000
M06.10 Adult-onset Still's disease (Multiple sites)
0.508 0.492 0.000
M06.29 Rheumatoid bursitis (Site unspecified)
0.508 0.492 0.000
M06.28 Rheumatoid bursitis (Other)
0.508 0.492 0.000
M06.27 Rheumatoid bursitis (Ankle and foot)
0.508 0.492 0.000
M06.26 Rheumatoid bursitis (Lower leg)
0.508 0.492 0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.508 0.492 0.000
M06.24 Rheumatoid bursitis (Hand)
0.508 0.492 0.000
M06.23 Rheumatoid bursitis (Forearm)
0.508 0.492 0.000
M06.22 Rheumatoid bursitis (Upper arm)
0.508 0.492 0.000
M06.21 Rheumatoid bursitis (Shoulder region)
0.508 0.492 0.000
M06.20 Rheumatoid bursitis (Multiple sites)
0.508 0.492 0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.508 0.492 0.000
M06.88 Other specified rheumatoid arthritis (Other)
0.508 0.492 0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.508 0.492 0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.508 0.492 0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.508 0.492 0.000
M06.84 Other specified rheumatoid arthritis (Hand)
0.508 0.492 0.000
M06.83 Other specified rheumatoid arthritis (Forearm)
0.508 0.492 0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.508 0.492 0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.508 0.492 0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.508 0.492 0.000
M03 Postinfective and reactive arthropathies in diseases classified elsewhere
0.506 0.494 0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere
0.506 0.494 0.000
E89.3 Postprocedural hypopituitarism
0.000 0.496 0.504
E53.8 Deficiency of other specified B group vitamins
0.000 0.498 0.501
M08.9 Juvenile arthritis, unspecified
0.499 0.501 0.000
M08.8 Other juvenile arthritis
0.499 0.501 0.000
M08.4 Pauciarticular juvenile arthritis
0.499 0.501 0.000
M08.3 Juvenile polyarthritis (seronegative)
0.499 0.501 0.000
M08.2 Juvenile arthritis with systemic onset
0.499 0.501 0.000
M08.1 Juvenile ankylosing spondylitis
0.499 0.501 0.000
M08.0 Juvenile rheumatoid arthritis
0.499 0.501 0.000
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.499 0.501 0.000
M09.2 Juvenile arthritis in ulcerative colitis
0.499 0.501 0.000
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.499 0.501 0.000
M09.0 Juvenile arthritis in psoriasis
0.499 0.501 0.000
M12.8 Other specific arthropathies, not elsewhere classified
0.499 0.501 0.000
M12.5 Traumatic arthropathy
0.499 0.501 0.000
M12.4 Intermittent hydrarthrosis
0.499 0.501 0.000
M12.3 Palindromic rheumatism
0.499 0.501 0.000
M12.2 Villonodular synovitis (pigmented)
0.499 0.501 0.000
M12.1 Kaschin-Beck disease
0.499 0.501 0.000
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.499 0.501 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.506 0.494
E22.8 Other hyperfunction of pituitary gland
0.000 0.506 0.494
E22.1 Hyperprolactinaemia
0.000 0.506 0.494
M40 Kyphosis and lordosis
0.494 0.506 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.506 0.494
E14.8 With unspecified complications
0.000 0.507 0.493
E14.7 With multiple complications
0.000 0.507 0.493
E14.6 With other specified complications
0.000 0.507 0.493
E14.5 With peripheral circulatory complications
0.000 0.507 0.493
E14.4 With neurological complications
0.000 0.507 0.493
E14.2 Withrenal complications
0.000 0.507 0.493
E14.1 With ketoacidosis
0.000 0.507 0.493
E14.0 With coma
0.000 0.507 0.493
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.509 0.491
E29 Testicular dysfunction
0.000 0.511 0.489
E87.1 Hypo-osmolality and hyponatraemia
0.000 0.511 0.489
M02.3 Reiter's disease
0.488 0.512 0.000
E15 Nondiabetic hypoglycaemic coma
0.000 0.512 0.488
M63 Disorders of muscle in diseases classified elsewhere
0.488 0.512 0.000
M61 Calcification and ossification of muscle
0.488 0.512 0.000
M60 Myositis
0.488 0.512 0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.487 0.512 0.000
E89.2 Postprocedural hypoparathyroidism
0.000 0.513 0.487
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)
0.485 0.515 0.000
M07.08 Distal interphalangeal proriatic arthropathy-Other
0.485 0.515 0.000
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)
0.485 0.515 0.000
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg
0.485 0.515 0.000
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh
0.485 0.515 0.000
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)
0.485 0.515 0.000
M07.03 Distal interphalangeal proriatic arthropathy-Forearm
0.485 0.515 0.000
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm
0.485 0.515 0.000
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region
0.485 0.515 0.000
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)
0.485 0.515 0.000
M07.19 Arthritis mutilans (Site unspecified)
0.485 0.515 0.000
M07.18 Arthritis mutilans (Other)
0.485 0.515 0.000
M07.17 Arthritis mutilans (Ankle and foot)
0.485 0.515 0.000
M07.16 Arthritis mutilans (Lower leg)
0.485 0.515 0.000
M07.15 Arthritis mutilans (Pelvic region and thigh)
0.485 0.515 0.000
M07.14 Arthritis mutilans (Hand)
0.485 0.515 0.000
M07.13 Arthritis mutilans (Forearm)
0.485 0.515 0.000
M07.12 Arthritis mutilans (Upper arm)
0.485 0.515 0.000
M07.11 Arthritis mutilans (Shoulder region)
0.485 0.515 0.000
M07.10 Arthritis mutilans (Multiple sites)
0.485 0.515 0.000
M07.29 Psoriatic spondylitis (Site unspecified)
0.485 0.515 0.000
M07.28 Psoriatic spondylitis (Other)
0.485 0.515 0.000
M07.27 Psoriatic spondylitis (Ankle and foot)
0.485 0.515 0.000
M07.26 Psoriatic spondylitis (Lower leg)
0.485 0.515 0.000
M07.25 Psoriatic spondylitis (Pelvic region and thigh)
0.485 0.515 0.000
M07.24 Psoriatic spondylitis (Hand)
0.485 0.515 0.000
M07.23 Psoriatic spondylitis (Forearm)
0.485 0.515 0.000
M07.22 Psoriatic spondylitis (Upper arm)
0.485 0.515 0.000
M07.21 Psoriatic spondylitis (Shoulder region)
0.485 0.515 0.000
M07.20 Psoriatic spondylitis (Multiple sites)
0.485 0.515 0.000
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)
0.485 0.515 0.000
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)
0.485 0.515 0.000
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)
0.485 0.515 0.000
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)
0.485 0.515 0.000
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)
0.485 0.515 0.000
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)
0.485 0.515 0.000
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)
0.485 0.515 0.000
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)
0.485 0.515 0.000
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)
0.485 0.515 0.000
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)
0.485 0.515 0.000
M07.59 Arthropathy in ulcerative colitis (Site unspecified)
0.485 0.515 0.000
M07.58 Arthropathy in ulcerative colitis (Other)
0.485 0.515 0.000
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)
0.485 0.515 0.000
M07.56 Arthropathy in ulcerative colitis (Lower leg)
0.485 0.515 0.000
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)
0.485 0.515 0.000
M07.54 Arthropathy in ulcerative colitis (Hand)
0.485 0.515 0.000
M07.53 Arthropathy in ulcerative colitis (Forearm)
0.485 0.515 0.000
M07.52 Arthropathy in ulcerative colitis (Upper arm)
0.485 0.515 0.000
M07.51 Arthropathy in ulcerative colitis (Shoulder region)
0.485 0.515 0.000
M07.50 Arthropathy in ulcerative colitis (Multiple sites)
0.485 0.515 0.000
M07.69 Other enteropathic arthropathies (Site unspecified)
0.485 0.515 0.000
M07.68 Other enteropathic arthropathies (Other)
0.485 0.515 0.000
M07.67 Other enteropathic arthropathies (Ankle and foot)
0.485 0.515 0.000
M07.66 Other enteropathic arthropathies (Lower leg)
0.485 0.515 0.000
M07.65 Other enteropathic arthropathies (Pelvic region and thigh)
0.485 0.515 0.000
M07.64 Other enteropathic arthropathies (Hand)
0.485 0.515 0.000
M07.63 Other enteropathic arthropathies (Forearm)
0.485 0.515 0.000
M07.62 Other enteropathic arthropathies (Upper arm)
0.485 0.515 0.000
M07.61 Other enteropathic arthropathies (Shoulder region)
0.485 0.515 0.000
M07.60 Other enteropathic arthropathies (Multiple sites)
0.485 0.515 0.000
M34 Systemic sclerosis
0.485 0.515 0.000
E27.8 Other specified disorders of adrenal gland
0.000 0.515 0.484
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.516 0.484
E21.4 Other specified disorders of parathyroid gland
0.000 0.516 0.484
E21.2 Other hyperparathyroidism
0.000 0.516 0.484
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.516 0.484
M00 Pyogenic arthritis
0.483 0.517 0.000
M11.9 Crystal arthropathy, unspecified
0.481 0.518 0.000
M11.8 Other specified crystal arthropathies
0.481 0.518 0.000
M11.1 Familial chondrocalcinosis
0.481 0.518 0.000
M11.0 Hydroxyapatite deposition disease
0.481 0.518 0.000
M92 Other juvenile osteochondrosis
0.481 0.519 0.000
E26.0 Primary hyperaldosteronism
0.000 0.521 0.479
E53.9 Vitamin B deficiency, unspecified
0.000 0.523 0.477
E53.1 Pyridoxine deficiency
0.000 0.523 0.477
E53.0 Riboflavin deficiency
0.000 0.523 0.477
M89 Other disorders of bone
0.476 0.524 0.000
M83 Adult osteomalacia
0.473 0.527 0.000
M82 Osteoporosis in diseases classified elsewhere
0.473 0.527 0.000
M65-M68 Disorders of synovium and tendon
0.470 0.530 0.000
M49.8 Spondylopathy in other diseases classified elsewhere
0.469 0.530 0.000
M49.5 Collapsed vertebra in diseases classified elsewhere
0.469 0.530 0.000
M49.4 Neuropathic spondylopathy
0.469 0.530 0.000
M49.3 Spondylopathy in other infectious and parasitic diseases classified elsewhere
0.469 0.530 0.000
M49.2 Enterobacterial spondylitis
0.469 0.530 0.000
M49.1 Brucella spondylitis
0.469 0.530 0.000
M49.0 Tuberculosis of spine
0.469 0.530 0.000
M50 Cervical disk disorders
0.467 0.533 0.000
E83.3 Disorders of phosphorus metabolism
0.000 0.534 0.466
M24 Other specific joint derangements
0.465 0.535 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.465 0.535 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.464 0.535 0.000
E88.9 Metabolic disorder, unspecified
0.000 0.537 0.463
E88.8 Other specified metabolic disorders
0.000 0.537 0.463
E88.3 Tumour lysis syndrome
0.000 0.537 0.463
E88.2 Lipomatosis, not elsewhere classified
0.000 0.537 0.463
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.537 0.463
E87.5 Hyperkalaemia
0.000 0.538 0.462
E73.9 Lactose intolerance, unspecified
0.000 0.538 0.462
E50.9 Vitamin A deficiency, unspecified
0.000 0.541 0.459
E50.8 Other manifestations of vitamin A deficiency
0.000 0.541 0.459
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.541 0.459
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.541 0.459
E50.5 Vitamin A deficiency with night blindness
0.000 0.541 0.459
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.541 0.459
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.541 0.459
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.541 0.459
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.541 0.459
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.541 0.459
E51.9 Thiamine deficiency, unspecified
0.000 0.541 0.459
E51.8 Other manifestations of thiamine deficiency
0.000 0.541 0.459
E51.2 Wernicke's encephalopathy
0.000 0.541 0.459
E51.1 Beriberi
0.000 0.541 0.459
E56.9 Vitamin deficiency, unspecified
0.000 0.541 0.459
E56.8 Deficiency of other vitamins
0.000 0.541 0.459
E56.1 Deficiency of vitamin K
0.000 0.541 0.459
E56.0 Deficiency of vitamin E
0.000 0.541 0.459
E63.9 Nutritional deficiency, unspecified
0.000 0.541 0.459
E63.8 Other specified nutritional deficiencies
0.000 0.541 0.459
E63.1 Imbalance of constituents of food intake
0.000 0.541 0.459
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.541 0.459
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.541 0.459
E64.8 Sequelae of other nutritional deficiencies
0.000 0.541 0.459
E64.3 Sequelae of rickets
0.000 0.541 0.459
E64.2 Sequelae of vitamin C deficiency
0.000 0.541 0.459
E64.1 Sequelae of vitamin A deficiency
0.000 0.541 0.459
E64.0 Sequelae of protein-energy malnutrition
0.000 0.541 0.459
M86 Osteomyelitis
0.459 0.541 0.000
M11.2 Other chondrocalcinosis
0.457 0.543 0.000
E87.4 Mixed disorder of acid-base balance
0.000 0.544 0.456
E16 Other disorders of pancreatic internal secretion
0.000 0.545 0.455
M42 Spinal osteochondrosis
0.454 0.545 0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.548 0.452
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.548 0.452
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.548 0.452
E89.5 Postprocedural testicular hypofunction
0.000 0.548 0.452
E89.4 Postprocedural ovarian failure
0.000 0.548 0.452
E89.1 Postprocedural hypoinsulinaemia
0.000 0.548 0.452
E89.0 Postprocedural hypothyroidism
0.000 0.553 0.447
M80.1 Postoophorectomy osteoporosis with pathological fracture
0.446 0.554 0.000
E26.9 Hyperaldosteronism, unspecified
0.000 0.554 0.445
E26.8 Other hyperaldosteronism
0.000 0.554 0.445
E26.1 Secondary hyperaldosteronism
0.000 0.554 0.445
M91 Juvenile osteochondrosis of hip and pelvis
0.445 0.555 0.000
E83.5 Disorders of calcium metabolism
0.000 0.556 0.444
E83.1 Disorders of iron metabolism
0.000 0.557 0.443
M21 Other acquired deformities of limbs
0.442 0.558 0.000
E85.4 Organ-limited amyloidosis
0.000 0.560 0.440
M34.9 Systemic sclerosis, unspecified
0.439 0.561 0.000
M46.4 Discitis, unspecified
0.438 0.562 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.436 0.564 0.000
E61.9 Deficiency of nutrient element, unspecified
0.000 0.565 0.435
E61.8 Deficiency of other specified nutrient elements
0.000 0.565 0.435
E61.7 Deficiency of multiple nutrient elements
0.000 0.565 0.435
E61.6 Vanadium deficiency
0.000 0.565 0.435
E61.5 Molybdenum deficiency
0.000 0.565 0.435
E61.4 Chromium deficiency
0.000 0.565 0.435

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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