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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs9380238
log Bayes Factor = 117.836
Chromosome 6   position 31,267,618  (GRCh37) Explore rs9380238 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
L40.5 Arthropathic psoriasis
1.000 0.000 0.000
L40 Psoriasis
1.000 0.000 0.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
M07.39 Other psoriatic arthropathies (Site unspecified)
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
L40.0 Psoriasis vulgaris
1.000 0.000 0.000
E03 Other hypothyroidism
0.000 0.000 1.000
M07.3 Other psoriatic arthropathies
0.999 0.001 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.002 0.998
E05.9 Thyrotoxicosis, unspecified
0.000 0.003 0.997
M07.30 Other psoriatic arthropathies (Multiple sites)
0.992 0.008 0.000
E07 Other disorders of thyroid
0.000 0.071 0.929
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.902 0.098 0.000
L40.8 Other psoriasis
0.897 0.103 0.000
E07.9 Disorder of thyroid, unspecified
0.000 0.112 0.888
L40.1 Generalised pustular psoriasis
0.885 0.115 0.000
M07.34 Other psoriatic arthropathies (Hand)
0.854 0.146 0.000
L40.4 Guttate psoriasis
0.839 0.161 0.000
E10 Insulin-dependent diabetes mellitus
0.000 0.169 0.831
M07.36 Other psoriatic arthropathies (Lower leg)
0.830 0.170 0.000
E10.9 Without complications
0.000 0.178 0.822
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.178 0.822
E10-E14 Diabetes mellitus
0.000 0.185 0.815
M07.31 Other psoriatic arthropathies (Shoulder region)
0.811 0.189 0.000
E10.4 With neurological complications
0.000 0.227 0.773
E06 Thyroiditis
0.000 0.263 0.737
M35.3 Polymyalgia rheumatica
0.000 0.278 0.722
E10.1 With ketoacidosis
0.000 0.279 0.721
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.279 0.721
L40.3 Pustulosis palmaris et plantaris
0.717 0.283 0.000
L40.2 Acrodermatitis continua
0.717 0.283 0.000
E05.8 Other thyrotoxicosis
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
M07.38 Other psoriatic arthropathies (Other)
0.716 0.284 0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.716 0.284 0.000
M07.33 Other psoriatic arthropathies (Forearm)
0.716 0.284 0.000
M07.32 Other psoriatic arthropathies (Upper arm)
0.716 0.284 0.000
E10.3 With ophthalmic complications
0.000 0.286 0.714
E70-E90 Metabolic disorders
0.000 0.294 0.706
E83 Disorders of mineral metabolism
0.000 0.301 0.699
M35 Other systemic involvement of connective tissue
0.000 0.311 0.689
M35.0 Sicca syndrome [Sjogren]
0.000 0.315 0.685
E10.5 With peripheral circulatory complications
0.000 0.327 0.673
E07.1 Dyshormogenetic goitre
0.000 0.334 0.666
E07.0 Hypersecretion of calcitonin
0.000 0.334 0.666
E10.2 With renal complications
0.000 0.339 0.661
E83.5 Disorders of calcium metabolism
0.000 0.345 0.655
E73 Lactose intolerance
0.000 0.354 0.646
E10.0 With coma
0.000 0.365 0.635
E83.1 Disorders of iron metabolism
0.000 0.390 0.610
E07.8 Other specified disorders of thyroid
0.000 0.394 0.606
E04 Other non-toxic goitre
0.000 0.395 0.605
E73.9 Lactose intolerance, unspecified
0.000 0.398 0.602
E83.3 Disorders of phosphorus metabolism
0.000 0.403 0.597
E10.7 With multiple complications
0.000 0.404 0.596
E03.8 Other specified hypothyroidism
0.000 0.415 0.584
E12 Malnutrition-related diabetes mellitus
0.000 0.415 0.584
E83.4 Disorders of magnesium metabolism
0.000 0.415 0.585
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.417 0.583
E85 Amyloidosis
0.000 0.425 0.575
E06.3 Autoimmune thyroiditis
0.000 0.445 0.555
E10.6 With other specified complications
0.000 0.454 0.546
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.467 0.533
E10.8 With unspecified complications
0.000 0.468 0.532
E06.5 Other chronic thyroiditis
0.000 0.472 0.528
E06.4 Drug-induced thyroiditis
0.000 0.472 0.528
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.472 0.528
E06.1 Subacute thyroiditis
0.000 0.472 0.528
E06.0 Acute thyroiditis
0.000 0.472 0.528
E74 Other disorders of carbohydrate metabolism
0.000 0.474 0.526
E06.9 Thyroiditis, unspecified
0.000 0.479 0.521
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E84 Cystic fibrosis
0.000 0.494 0.506
E79 Disorders of purine and pyrimidine metabolism
0.000 0.494 0.506
E77 Disorders of glycoprotein metabolism
0.000 0.494 0.506
E76 Disorders of glycosaminoglycan metabolism
0.000 0.494 0.506
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.494 0.506
E72 Other disorders of amino-acid metabolism
0.000 0.494 0.506
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.494 0.506
E70 Disorders of aromatic amino-acid metabolism
0.000 0.494 0.506
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.494 0.506
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.499 0.501
E83.8 Other disorders of mineral metabolism
0.000 0.499 0.501
E83.2 Disorders of zinc metabolism
0.000 0.499 0.501
E83.0 Disorders of copper metabolism
0.000 0.499 0.501
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.506 0.494
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.506 0.494
M35.5 Multifocal fibrosclerosis
0.000 0.506 0.494
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.506 0.494
M35.1 Other overlap syndromes
0.000 0.506 0.494
E40-E46 Malnutrition
0.000 0.508 0.492
M35.2 Behcet's disease
0.000 0.508 0.492
M35.7 Hypermobility syndrome
0.000 0.511 0.489
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.512 0.487
E50-E64 Other nutritional deficiencies
0.000 0.512 0.488
E85.9 Amyloidosis, unspecified
0.000 0.515 0.485
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.532 0.468
M35.8 Other specified systemic involvement of connective tissue
0.000 0.532 0.468
E73.8 Other lactose intolerance
0.000 0.537 0.463
E73.1 Secondary lactase deficiency
0.000 0.537 0.463
E73.0 Congenital lactase deficiency
0.000 0.537 0.463
E04.9 Non-toxic goitre, unspecified
0.000 0.538 0.462
E13 Other specified diabetes mellitus
0.000 0.551 0.449
E04.8 Other specified non-toxic goitre
0.000 0.566 0.434
M07 Psoriatic and enteropathic arthropathies
0.431 0.569 0.000
E12.9 Without complications
0.000 0.581 0.419
E12.8 With unspecified complications
0.000 0.581 0.419
E12.7 With multiple complications
0.000 0.581 0.419
E12.6 With other specified complications
0.000 0.581 0.419
E12.5 With peripheral circulatory complications
0.000 0.581 0.419
E12.4 With neurological complications
0.000 0.581 0.419
E12.3 With ophthalmic complications
0.000 0.581 0.419
E12.2 With renal complications
0.000 0.581 0.419
E12.1 With ketoacidosis
0.000 0.581 0.419
E12.0 With coma
0.000 0.581 0.419
E85.8 Other amyloidosis
0.000 0.588 0.412
E85.3 Secondary systemic amyloidosis
0.000 0.588 0.412
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.588 0.412
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.588 0.412
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.588 0.412
E20-E35 Disorders of other endocrine glands
0.000 0.590 0.410
E04.1 Non-toxic single thyroid nodule
0.000 0.593 0.407
E85.4 Organ-limited amyloidosis
0.000 0.596 0.404
E04.2 Non-toxic multinodular goitre
0.000 0.600 0.400
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.603 0.396
E15 Nondiabetic hypoglycaemic coma
0.000 0.618 0.382
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.622 0.378
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.623 0.377
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.623 0.377
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.623 0.377
E74.2 Disorders of galactose metabolism
0.000 0.623 0.377
E74.1 Disorders of fructose metabolism
0.000 0.623 0.377
E74.0 Glycogen storage disease
0.000 0.623 0.377
E88 Other metabolic disorders
0.000 0.634 0.366
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.637 0.363
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.637 0.363
E70.3 Albinism
0.000 0.637 0.363
E70.2 Disorders of tyrosine metabolism
0.000 0.637 0.363
E70.1 Other hyperphenylalaninaemias
0.000 0.637 0.363
E70.0 Classical phenylketonuria
0.000 0.637 0.363
E71.3 Disorders of fatty-acid metabolism
0.000 0.637 0.363
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.637 0.363
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.637 0.363
E71.0 Maple-syrup-urine disease
0.000 0.637 0.363
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.637 0.363
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.637 0.363
E72.5 Disorders of glycine metabolism
0.000 0.637 0.363
E72.4 Disorders of ornithine metabolism
0.000 0.637 0.363
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.637 0.363
E72.2 Disorders of urea cycle metabolism
0.000 0.637 0.363
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.637 0.363
E72.0 Disorders of amino-acid transport
0.000 0.637 0.363
E75.6 Lipid storage disorder, unspecified
0.000 0.637 0.363
E75.5 Other lipid storage disorders
0.000 0.637 0.363
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.637 0.363
E75.3 Sphingolipidosis, unspecified
0.000 0.637 0.363
E75.2 Other sphingolipidosis
0.000 0.637 0.363
E75.1 Other gangliosidosis
0.000 0.637 0.363
E75.0 GM2 gangliosidosis
0.000 0.637 0.363
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.637 0.363
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.637 0.363
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.637 0.363
E76.2 Other mucopolysaccharidoses
0.000 0.637 0.363
E76.1 Mucopolysaccharidosis, type II
0.000 0.637 0.363
E76.0 Mucopolysaccharidosis, type I
0.000 0.637 0.363
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.637 0.363
E77.8 Other disorders of glycoprotein metabolism
0.000 0.637 0.363
E77.1 Defects in glycoprotein degradation
0.000 0.637 0.363
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.637 0.363
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.637 0.363
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.637 0.363
E79.1 Lesch-Nyhan syndrome
0.000 0.637 0.363
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.637 0.363
E84.9 Cystic fibrosis, unspecified
0.000 0.637 0.363
E84.8 Cystic fibrosis with other manifestations
0.000 0.637 0.363
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.637 0.363
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.637 0.363
E89.0 Postprocedural hypothyroidism
0.000 0.637 0.363
E14 Unspecified diabetes mellitus
0.000 0.638 0.361
E04.0 Non-toxic diffuse goitre
0.000 0.641 0.359
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified
0.000 0.646 0.354
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.647 0.353
E45 Retarded development following protein-energy malnutrition
0.000 0.647 0.353
E43 Unspecified severe protein-energy malnutrition
0.000 0.647 0.353
E42 Marasmic kwashiorkor
0.000 0.647 0.353
E41 Nutritional marasmus
0.000 0.647 0.353
E40 Kwashiorkor
0.000 0.647 0.353
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.650 0.350
E63 Other nutritional deficiencies
0.000 0.650 0.350
E56 Other vitamin deficiencies
0.000 0.650 0.350
E51 Thiamine deficiency
0.000 0.650 0.350
E50 Vitamin A deficiency
0.000 0.650 0.350
E60 Dietary zinc deficiency
0.000 0.650 0.350
E59 Dietary selenium deficiency
0.000 0.650 0.350
E58 Dietary calcium deficiency
0.000 0.650 0.350
E54 Ascorbic acid deficiency
0.000 0.650 0.350
E52 Niacin deficiency [pellagra]
0.000 0.650 0.350
E89.3 Postprocedural hypopituitarism
0.000 0.658 0.342
E65-E68 Obesity and other hyperalimentation
0.000 0.658 0.342
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.662 0.338
K90 Intestinal malabsorption
0.000 0.664 0.336
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.664 0.336
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.664 0.336
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.664 0.336
E89.5 Postprocedural testicular hypofunction
0.000 0.664 0.336
E89.4 Postprocedural ovarian failure
0.000 0.664 0.336
E89.1 Postprocedural hypoinsulinaemia
0.000 0.664 0.336
E53 Deficiency of other B group vitamins
0.000 0.669 0.331
E87.0 Hyperosmolality and hypernatraemia
0.000 0.672 0.328
E16 Other disorders of pancreatic internal secretion
0.000 0.674 0.326
E55 Vitamin D deficiency
0.000 0.678 0.322
E13.8 With unspecified complications
0.000 0.678 0.322
E13.7 With multiple complications
0.000 0.678 0.322
E13.6 With other specified complications
0.000 0.678 0.322
E13.5 With peripheral circulatory complications
0.000 0.678 0.322
E13.4 With neurological complications
0.000 0.678 0.322
E13.3 With ophthalmic complications
0.000 0.678 0.322
E13.2 With renal complications
0.000 0.678 0.322
E13.1 With ketoacidosis
0.000 0.678 0.322
E13.0 With coma
0.000 0.678 0.322
E22 Hyperfunction of pituitary gland
0.000 0.681 0.319
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.683 0.317
E28 Ovarian dysfunction
0.000 0.686 0.314
E34 Other endocrine disorders
0.000 0.686 0.313
E20 Hypoparathyroidism
0.000 0.689 0.311
E61 Deficiency of other nutrient elements
0.000 0.689 0.311
M07.6 Other enteropathic arthropathies
0.309 0.691 0.000
M07.5 Arthropathy in ulcerative colitis
0.309 0.691 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.309 0.691 0.000
M07.2 Psoriatic spondylitis
0.309 0.691 0.000
M07.1 Arthritis mutilans
0.309 0.691 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.309 0.691 0.000
E29 Testicular dysfunction
0.000 0.695 0.305
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.706 0.294
E32 Diseases of thymus
0.000 0.706 0.294
E31 Polyglandular dysfunction
0.000 0.706 0.294
E30 Disorders of puberty, not elsewhere classified
0.000 0.706 0.294
E26 Hyperaldosteronism
0.000 0.708 0.291
E27 Other disorders of adrenal gland
0.000 0.708 0.291
E87.1 Hypo-osmolality and hyponatraemia
0.000 0.709 0.291
E21.0 Primary hyperparathyroidism
0.000 0.721 0.279
E27.1 Primary adrenocortical insufficiency
0.000 0.726 0.274
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.729 0.271
E80.6 Other disorders of bilirubin metabolism
0.000 0.729 0.271
E80.5 Crigler-Najjar syndrome
0.000 0.729 0.271
E80.3 Defects of catalase and peroxydase
0.000 0.729 0.271
E80.2 Other porphyria
0.000 0.729 0.271
E80.1 Porphyria cutanea tarda
0.000 0.729 0.271
E80.0 Hereditary erythropoietic porphyria
0.000 0.729 0.271
E88.9 Metabolic disorder, unspecified
0.000 0.737 0.263
E88.3 Tumour lysis syndrome
0.000 0.737 0.263
E14.3 With ophthalmic complications
0.000 0.739 0.261
E14.8 With unspecified complications
0.000 0.741 0.259
E14.7 With multiple complications
0.000 0.741 0.259
E14.6 With other specified complications
0.000 0.741 0.259
E14.5 With peripheral circulatory complications
0.000 0.741 0.259
E14.2 Withrenal complications
0.000 0.741 0.259
E14.1 With ketoacidosis
0.000 0.741 0.259
E14.0 With coma
0.000 0.741 0.259
E46 Unspecified protein-energy malnutrition
0.000 0.744 0.256
E44.1 Mild protein-energy malnutrition
0.000 0.747 0.253
E44.0 Moderate protein-energy malnutrition
0.000 0.747 0.253
E50.9 Vitamin A deficiency, unspecified
0.000 0.749 0.251
E50.8 Other manifestations of vitamin A deficiency
0.000 0.749 0.251
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.749 0.251
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.749 0.251
E50.5 Vitamin A deficiency with night blindness
0.000 0.749 0.251
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.749 0.251
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.749 0.251
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.749 0.251
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.749 0.251
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.749 0.251
E51.9 Thiamine deficiency, unspecified
0.000 0.749 0.251
E51.8 Other manifestations of thiamine deficiency
0.000 0.749 0.251
E51.2 Wernicke's encephalopathy
0.000 0.749 0.251
E51.1 Beriberi
0.000 0.749 0.251
E56.9 Vitamin deficiency, unspecified
0.000 0.749 0.251
E56.8 Deficiency of other vitamins
0.000 0.749 0.251
E56.1 Deficiency of vitamin K
0.000 0.749 0.251
E56.0 Deficiency of vitamin E
0.000 0.749 0.251
E63.9 Nutritional deficiency, unspecified
0.000 0.749 0.251
E63.8 Other specified nutritional deficiencies
0.000 0.749 0.251
E63.1 Imbalance of constituents of food intake
0.000 0.749 0.251
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.749 0.251
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.749 0.251
E64.8 Sequelae of other nutritional deficiencies
0.000 0.749 0.251
E64.3 Sequelae of rickets
0.000 0.749 0.251
E64.2 Sequelae of vitamin C deficiency
0.000 0.749 0.251
E64.1 Sequelae of vitamin A deficiency
0.000 0.749 0.251
E64.0 Sequelae of protein-energy malnutrition
0.000 0.749 0.251
E34.0 Carcinoid syndrome
0.000 0.751 0.249
E22.1 Hyperprolactinaemia
0.000 0.751 0.249
E22.0 Acromegaly and pituitary gigantism
0.000 0.753 0.247
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.753 0.247
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.753 0.247
E88.2 Lipomatosis, not elsewhere classified
0.000 0.753 0.246
E88.8 Other specified metabolic disorders
0.000 0.754 0.246
E67 Other hyperalimentation
0.000 0.755 0.245
E68 Sequelae of hyperalimentation
0.000 0.755 0.245
E28.2 Polycystic ovarian syndrome
0.000 0.755 0.245
L40-L45 Papulosquamous disorders
0.244 0.756 0.000
E89.2 Postprocedural hypoparathyroidism
0.000 0.757 0.243
E87.4 Mixed disorder of acid-base balance
0.000 0.757 0.242
E87.3 Alkalosis
0.000 0.759 0.241
K90.8 Other intestinal malabsorption
0.000 0.759 0.241
K90.3 Pancreatic steatorrhoea
0.000 0.759 0.241
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.759 0.241
K90.1 Tropical sprue
0.000 0.759 0.241
E20.9 Hypoparathyroidism, unspecified
0.000 0.760 0.240
E53.9 Vitamin B deficiency, unspecified
0.000 0.762 0.238
E53.1 Pyridoxine deficiency
0.000 0.762 0.238
E53.0 Riboflavin deficiency
0.000 0.762 0.238
E34.8 Other specified endocrine disorders
0.000 0.766 0.234
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.766 0.234
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.766 0.234
E16.4 Abnormal secretion of gastrin
0.000 0.766 0.234
E16.3 Increased secretion of glucagon
0.000 0.766 0.234
E55.0 Rickets, active
0.000 0.769 0.231
E29.1 Testicular hypofunction
0.000 0.770 0.230
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.771 0.229
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.771 0.229
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.771 0.229
E22.8 Other hyperfunction of pituitary gland
0.000 0.771 0.229
E65 Localised adiposity
0.000 0.771 0.228
E21.4 Other specified disorders of parathyroid gland
0.000 0.773 0.227
E21.2 Other hyperparathyroidism
0.000 0.773 0.227
E28.9 Ovarian dysfunction, unspecified
0.000 0.775 0.225
E28.8 Other ovarian dysfunction
0.000 0.775 0.225
E28.3 Primary ovarian failure
0.000 0.775 0.225
E28.1 Androgen excess
0.000 0.775 0.225
E28.0 Oestrogen excess
0.000 0.775 0.225
E34.5 Androgen resistance syndrome
0.000 0.775 0.225
E34.4 Constitutional tall stature
0.000 0.775 0.225
E34.3 Short stature, not elsewhere classified
0.000 0.775 0.225
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.775 0.225
E34.1 Other hypersecretion of intestinal hormones
0.000 0.775 0.225
E25 Adrenogenital disorders
0.001 0.775 0.224
E27.2 Addisonian crisis
0.000 0.776 0.223
E20.8 Other hypoparathyroidism
0.000 0.777 0.223
E20.1 Pseudohypoparathyroidism
0.000 0.777 0.223
E20.0 Idiopathic hypoparathyroidism
0.000 0.777 0.223
E61.9 Deficiency of nutrient element, unspecified
0.000 0.777 0.223
E61.8 Deficiency of other specified nutrient elements
0.000 0.777 0.223
E61.7 Deficiency of multiple nutrient elements
0.000 0.777 0.223
E61.6 Vanadium deficiency
0.000 0.777 0.223
E61.5 Molybdenum deficiency
0.000 0.777 0.223
E61.4 Chromium deficiency
0.000 0.777 0.223
E61.3 Manganese deficiency
0.000 0.777 0.223
E61.2 Magnesium deficiency
0.000 0.777 0.223
E61.0 Copper deficiency
0.000 0.777 0.223
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)
0.221 0.778 0.000
M07.08 Distal interphalangeal proriatic arthropathy-Other
0.221 0.778 0.000
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)
0.221 0.778 0.000
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg
0.221 0.778 0.000
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh
0.221 0.778 0.000
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)
0.221 0.778 0.000
M07.03 Distal interphalangeal proriatic arthropathy-Forearm
0.221 0.778 0.000
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm
0.221 0.778 0.000
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region
0.221 0.778 0.000
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)
0.221 0.778 0.000
M07.19 Arthritis mutilans (Site unspecified)
0.221 0.778 0.000
M07.18 Arthritis mutilans (Other)
0.221 0.778 0.000
M07.17 Arthritis mutilans (Ankle and foot)
0.221 0.778 0.000
M07.16 Arthritis mutilans (Lower leg)
0.221 0.778 0.000
M07.15 Arthritis mutilans (Pelvic region and thigh)
0.221 0.778 0.000
M07.14 Arthritis mutilans (Hand)
0.221 0.778 0.000
M07.13 Arthritis mutilans (Forearm)
0.221 0.778 0.000
M07.12 Arthritis mutilans (Upper arm)
0.221 0.778 0.000
M07.11 Arthritis mutilans (Shoulder region)
0.221 0.778 0.000
M07.10 Arthritis mutilans (Multiple sites)
0.221 0.778 0.000
M07.29 Psoriatic spondylitis (Site unspecified)
0.221 0.778 0.000
M07.28 Psoriatic spondylitis (Other)
0.221 0.778 0.000
M07.27 Psoriatic spondylitis (Ankle and foot)
0.221 0.778 0.000
M07.26 Psoriatic spondylitis (Lower leg)
0.221 0.778 0.000
M07.25 Psoriatic spondylitis (Pelvic region and thigh)
0.221 0.778 0.000
M07.24 Psoriatic spondylitis (Hand)
0.221 0.778 0.000
M07.23 Psoriatic spondylitis (Forearm)
0.221 0.778 0.000
M07.22 Psoriatic spondylitis (Upper arm)
0.221 0.778 0.000
M07.21 Psoriatic spondylitis (Shoulder region)
0.221 0.778 0.000
M07.20 Psoriatic spondylitis (Multiple sites)
0.221 0.778 0.000
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)
0.221 0.778 0.000
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)
0.221 0.778 0.000
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)
0.221 0.778 0.000
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)
0.221 0.778 0.000
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)
0.221 0.778 0.000
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)
0.221 0.778 0.000
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)
0.221 0.778 0.000
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)
0.221 0.778 0.000
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)
0.221 0.778 0.000
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)
0.221 0.778 0.000
M07.59 Arthropathy in ulcerative colitis (Site unspecified)
0.221 0.778 0.000
M07.58 Arthropathy in ulcerative colitis (Other)
0.221 0.778 0.000
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)
0.221 0.778 0.000
M07.56 Arthropathy in ulcerative colitis (Lower leg)
0.221 0.778 0.000
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)
0.221 0.778 0.000
M07.54 Arthropathy in ulcerative colitis (Hand)
0.221 0.778 0.000
M07.53 Arthropathy in ulcerative colitis (Forearm)
0.221 0.778 0.000
M07.52 Arthropathy in ulcerative colitis (Upper arm)
0.221 0.778 0.000
M07.51 Arthropathy in ulcerative colitis (Shoulder region)
0.221 0.778 0.000
M07.50 Arthropathy in ulcerative colitis (Multiple sites)
0.221 0.778 0.000
M07.69 Other enteropathic arthropathies (Site unspecified)
0.221 0.778 0.000
M07.68 Other enteropathic arthropathies (Other)
0.221 0.778 0.000
M07.67 Other enteropathic arthropathies (Ankle and foot)
0.221 0.778 0.000
M07.66 Other enteropathic arthropathies (Lower leg)
0.221 0.778 0.000
M07.65 Other enteropathic arthropathies (Pelvic region and thigh)
0.221 0.778 0.000
M07.64 Other enteropathic arthropathies (Hand)
0.221 0.778 0.000
M07.63 Other enteropathic arthropathies (Forearm)
0.221 0.778 0.000
M07.62 Other enteropathic arthropathies (Upper arm)
0.221 0.778 0.000
M07.61 Other enteropathic arthropathies (Shoulder region)
0.221 0.778 0.000
M07.60 Other enteropathic arthropathies (Multiple sites)
0.221 0.778 0.000
E14.4 With neurological complications
0.000 0.780 0.219
E53.8 Deficiency of other specified B group vitamins
0.000 0.781 0.219
E29.9 Testicular dysfunction, unspecified
0.000 0.781 0.219
E29.8 Other testicular dysfunction
0.000 0.781 0.219
E29.0 Testicular hyperfunction
0.000 0.781 0.219
E21.3 Hyperparathyroidism, unspecified
0.000 0.784 0.216
E16.1 Other hypoglycaemia
0.000 0.785 0.214
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.787 0.213
E30.9 Disorder of puberty, unspecified
0.000 0.789 0.211
E30.8 Other disorders of puberty
0.000 0.789 0.211
E30.1 Precocious puberty
0.000 0.789 0.211
E30.0 Delayed puberty
0.000 0.789 0.211
E31.9 Polyglandular dysfunction, unspecified
0.000 0.789 0.211
E31.8 Other polyglandular dysfunction
0.000 0.789 0.211
E31.1 Polyglandular hyperfunction
0.000 0.789 0.211
E31.0 Autoimmune polyglandular failure
0.000 0.789 0.211
E32.9 Disease of thymus, unspecified
0.000 0.789 0.211
E32.8 Other diseases of thymus
0.000 0.789 0.211
E32.1 Abscess of thymus
0.000 0.789 0.211
E32.0 Persistent hyperplasia of thymus
0.000 0.789 0.211
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.789 0.211
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.789 0.211
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.789 0.211
E26.9 Hyperaldosteronism, unspecified
0.000 0.791 0.209
E26.8 Other hyperaldosteronism
0.000 0.791 0.209
E26.1 Secondary hyperaldosteronism
0.000 0.791 0.209
E27.5 Adrenomedullary hyperfunction
0.000 0.791 0.209
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.791 0.209
E27.0 Other adrenocortical overactivity
0.000 0.791 0.209
E87.6 Hypokalaemia
0.000 0.791 0.209
E34.9 Endocrine disorder, unspecified
0.000 0.793 0.207
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.793 0.207
E26.0 Primary hyperaldosteronism
0.000 0.794 0.206
E55.9 Vitamin D deficiency, unspecified
0.000 0.796 0.204
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.799 0.201
E13.9 Without complications
0.001 0.813 0.186
E24 Cushing's syndrome
0.001 0.813 0.186
E61.1 Iron deficiency
0.000 0.815 0.185
E16.2 Hypoglycaemia, unspecified
0.000 0.816 0.184
E67.8 Other specified hyperalimentation
0.000 0.824 0.176
E67.3 Hypervitaminosis D
0.000 0.824 0.176
E67.2 Megavitamin-B6 syndrome
0.000 0.824 0.176
E67.1 Hypercarotenaemia
0.000 0.824 0.176
E67.0 Hypervitaminosis A
0.000 0.824 0.176
K90.9 Intestinal malabsorption, unspecified
0.000 0.825 0.175
L44 Other papulosquamous disorders
0.175 0.825 0.000
L41 Parapsoriasis
0.175 0.825 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.175 0.825 0.000
L42 Pityriasis rosea
0.170 0.830 0.000
E25.9 Adrenogenital disorder, unspecified
0.001 0.838 0.161
E25.8 Other adrenogenital disorders
0.001 0.838 0.161
E27.8 Other specified disorders of adrenal gland
0.001 0.850 0.149
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.000 0.854 0.145
E87.7 Fluid overload
0.000 0.855 0.145
E23 Hypofunction and other disorders of pituitary gland
0.001 0.855 0.144
E80.4 Gilbert's syndrome
0.000 0.857 0.142
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.858 0.142
E27.9 Disorder of adrenal gland, unspecified
0.001 0.864 0.135
E24.8 Other Cushing's syndrome
0.001 0.866 0.133
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.001 0.866 0.133
E24.3 Ectopic ACTH syndrome
0.001 0.866 0.133
E24.2 Drug-induced Cushing's syndrome
0.001 0.866 0.133
E24.1 Nelson's syndrome
0.001 0.866 0.133
L41.9 Parapsoriasis, unspecified
0.126 0.874 0.000
L41.8 Other parapsoriasis
0.126 0.874 0.000
L41.5 Retiform parapsoriasis
0.126 0.874 0.000
L41.4 Large plaque parapsoriasis
0.126 0.874 0.000
L41.3 Small plaque parapsoriasis
0.126 0.874 0.000
L41.2 Lymphomatoid papulosis
0.126 0.874 0.000
L41.1 Pityriasis lichenoides chronica
0.126 0.874 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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