TreeWAS – Variant ID: rs9394047

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M45.X9 Ankylosing spondylitis (Site unspecified)	1.000	0.000	0.000
M45 Ankylosing spondylitis	1.000	0.000	0.000
M45-M49 Spondylopathies	1.000	0.000	0.000
E03.9 Hypothyroidism, unspecified	0.000	0.001	0.999
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.999	0.001	0.000
M05-M14 Inflammatory polyarthropathies	0.999	0.001	0.000
M06 Other rheumatoid arthritis	0.998	0.002	0.000
# Top node	0.996	0.004	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.996	0.004	0.000
M06.9 Rheumatoid arthritis, unspecified	0.996	0.004	0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.994	0.006	0.000
O60-O75 Complications of labour and delivery	0.982	0.018	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.980	0.020	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.980	0.020	0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.967	0.033	0.000
Chapter V Mental and behavioural disorders	0.966	0.034	0.000
O63 Long labour	0.965	0.035	0.000
M48 Other spondylopathies	0.963	0.037	0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.961	0.039	0.000
F10 Mental and behavioural disorders due to use of alcohol	0.957	0.043	0.000
K90.0 Coeliac disease	0.000	0.044	0.956
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.954	0.046	0.000
O63.1 Prolonged second stage (of labour)	0.952	0.048	0.000
O42 Premature rupture of membranes	0.948	0.052	0.000
O00-O08 Pregnancy with abortive outcome	0.944	0.056	0.000
M06.0 Seronegative rheumatoid arthritis	0.942	0.058	0.000
Chapter I Certain infectious and parasitic diseases	0.936	0.064	0.000
F10.2 Dependence syndrome	0.927	0.073	0.000
M07 Psoriatic and enteropathic arthropathies	0.926	0.074	0.000
M48.0 Spinal stenosis	0.921	0.079	0.000
O75 Other complications of labour and delivery, not elsewhere classified	0.920	0.080	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.916	0.084	0.000
M48.02 Spinal stenosis (Cervical region)	0.907	0.093	0.000
O42.9 Premature rupture of membranes, unspecified	0.890	0.110	0.000
L20-L30 Dermatitis and eczema	0.889	0.111	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.887	0.113	0.000
A30-A49 Other bacterial diseases	0.881	0.119	0.000
Chapter VI Diseases of the nervous system	0.876	0.124	0.000
M07.3 Other psoriatic arthropathies	0.874	0.126	0.000
O02 Other abnormal products of conception	0.874	0.126	0.000
O32 Maternal care for known or suspected malpresentation of foetus	0.872	0.128	0.000
F99-F99 Unspecified mental disorder	0.872	0.128	0.000
O20-O29 Other maternal disorders predominantly related to pregnancy	0.867	0.133	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.864	0.136	0.000
O04 Medical abortion	0.863	0.137	0.000
L80-L99 Other disorders of the skin and subcutaneous tissue	0.859	0.141	0.000
L29 Pruritus	0.858	0.142	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.856	0.144	0.000
M60-M63 Disorders of muscles	0.855	0.145	0.000
F10.3 Withdrawal state	0.854	0.146	0.000
O75.0 Maternal distress during labour and delivery	0.849	0.151	0.000
O63.9 Long labour, unspecified	0.845	0.155	0.000
A46 Erysipelas	0.844	0.156	0.000
L40-L45 Papulosquamous disorders	0.844	0.156	0.000
O30 Multiple gestation	0.843	0.157	0.000
F10.1 Harmful use	0.840	0.160	0.000
O02.1 Missed abortion	0.837	0.163	0.000
G90-G99 Other disorders of the nervous system	0.831	0.169	0.000
L97 Ulcer of lower limb, not elsewhere classified	0.830	0.170	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.828	0.172	0.000
F11 Mental and behavioural disorders due to use of opioids	0.828	0.172	0.000
M86-M90 Other osteopathies	0.827	0.173	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.826	0.174	0.000
M45.X2 Ankylosing spondylitis (Cervical region)	0.825	0.175	0.000
Q80-Q89 Other congenital malformations	0.824	0.176	0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.824	0.176	0.000
L10-L14 Bullous disorders	0.812	0.188	0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.809	0.191	0.000
L00-L08 Infections of the skin and subcutaneous tissue	0.806	0.194	0.000
G91 Hydrocephalus	0.805	0.195	0.000
F99 Mental disorder, not otherwise specified	0.804	0.196	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.803	0.197	0.000
O73 Retained placenta and membranes, without haemorrhage	0.801	0.199	0.000
O47 False labour	0.798	0.202	0.000
B99-B99 Other infectious diseases	0.796	0.204	0.000
M46 Other inflammatory spondylopathies	0.794	0.206	0.000
M48.5 Collapsed vertebra, not elsewhere classified	0.793	0.207	0.000
M06.4 Inflammatory polyarthropathy	0.792	0.208	0.000
A00-A09 Intestinal infectious diseases	0.791	0.209	0.000
O75.2 Pyrexia during labour, not elsewhere classified	0.790	0.210	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.785	0.215	0.000
L29.0 Pruritus ani	0.784	0.216	0.000
L29.2 Pruritus vulvae	0.784	0.216	0.000
O04.9 Complete or unspecified, without complication	0.782	0.218	0.000
O26 Maternal care for other conditions predominantly related to pregnancy	0.782	0.218	0.000
O72 Postpartum haemorrhage	0.779	0.221	0.000
G91.9 Hydrocephalus, unspecified	0.775	0.225	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.775	0.225	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.774	0.226	0.000
L40 Psoriasis	0.773	0.227	0.000
O69 Labour and delivery complicated by umbilical cord complications	0.772	0.228	0.000
M40-M43 Deforming dorsopathies	0.772	0.228	0.000
O85-O92 Complications predominantly related to the puerperium	0.768	0.232	0.000
O43 Placental disorders	0.760	0.240	0.000
Chapter X Diseases of the respiratory system	0.760	0.240	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.755	0.245	0.000
G63 Polyneuropathy in diseases classified elsewhere	0.755	0.245	0.000
O30.0 Twin pregnancy	0.754	0.246	0.000
B25-B34 Other viral diseases	0.753	0.247	0.000
M48.04 Spinal stenosis (Thoracic region)	0.752	0.248	0.000
L40.5 Arthropathic psoriasis	0.752	0.248	0.000
L92 Granulomatous disorders of skin and subcutaneous tissue	0.749	0.251	0.000
M00-M03 Infectious arthropathies	0.749	0.251	0.000
M11 Other crystal arthropathies	0.748	0.252	0.000
A08 Viral and other specified intestinal infections	0.747	0.253	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.742	0.258	0.000
F10.4 Withdrawal state with delirium	0.742	0.258	0.000
G60 Hereditary and idiopathic neuropathy	0.739	0.260	0.000
M48.09 Spinal stenosis (Site unspecified)	0.739	0.261	0.000
F70-F79 Mental retardation	0.738	0.262	0.000
L83 Acanthosis nigricans	0.737	0.263	0.000
O66 Other obstructed labour	0.736	0.264	0.000
Q12 Congenital lens malformations	0.735	0.265	0.000
A49 Bacterial infection of unspecified site	0.735	0.265	0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.734	0.266	0.000
O32.0 Maternal care for unstable lie	0.734	0.266	0.000
M14 Arthropathies in other diseases classified elsewhere	0.732	0.267	0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.731	0.269	0.000
B15-B19 Viral hepatitis	0.727	0.273	0.000
F10.5 Psychotic disorder	0.726	0.274	0.000
Chapter XXII Codes for special purposes	0.723	0.277	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.722	0.278	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.720	0.280	0.000
L50-L54 Urticaria and erythema	0.719	0.281	0.000
B50-B64 Protozoal diseases	0.718	0.282	0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.717	0.283	0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.717	0.283	0.000
M45.X6 Ankylosing spondylitis (Lumbar region)	0.717	0.283	0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.717	0.283	0.000
M45.X4 Ankylosing spondylitis (Thoracic region)	0.717	0.283	0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.717	0.283	0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.717	0.283	0.000
Q18 Other congenital malformations of face and neck	0.717	0.283	0.000
F60-F69 Disorders of adult personality and behaviour	0.716	0.284	0.000
M12 Other specific arthropathies	0.716	0.284	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.716	0.284	0.000
M08 Juvenile arthritis	0.716	0.284	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.716	0.284	0.000
M06.8 Other specified rheumatoid arthritis	0.716	0.284	0.000
M06.2 Rheumatoid bursitis	0.716	0.284	0.000
M06.1 Adult-onset Still's disease	0.716	0.284	0.000
B20-B24 Human immunodeficiency virus [HIV] disease	0.715	0.285	0.000
O64 Obstructed labour due to malposition and malpresentation of foetus	0.715	0.285	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.714	0.285	0.000
G70-G73 Diseases of myoneural junction and muscle	0.714	0.286	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.714	0.286	0.000
M49 Spondylopathies in diseases classified elsewhere	0.714	0.286	0.000
M62 Other disorders of muscle	0.713	0.287	0.000
O72.2 Delayed and secondary postpartum haemorrhage	0.713	0.287	0.000
O40 Polyhydramnios	0.709	0.291	0.000
Chapter XX External causes of morbidity and mortality	0.708	0.292	0.000
O32.8 Maternal care for other malpresentation of foetus	0.707	0.293	0.000
G90 Disorders of autonomic nervous system	0.706	0.294	0.000
J30-J39 Other diseases of upper respiratory tract	0.705	0.295	0.000
G63.2 Diabetic polyneuropathy	0.705	0.295	0.000
O74 Complications of anaesthesia during labour and delivery	0.704	0.296	0.000
O65 Obstructed labour due to maternal pelvic abnormality	0.704	0.296	0.000
O60 Preterm delivery	0.704	0.296	0.000
F10.9 Unspecified mental and behavioural disorder	0.703	0.297	0.000
O61 Failed induction of labour	0.700	0.299	0.000
O75.8 Other specified complications of labour and delivery	0.699	0.300	0.000
A50-A64 Infections with a predominantly sexual mode of transmission	0.699	0.301	0.000
O35 Maternal care for known or suspected foetal abnormality and damage	0.698	0.302	0.000
M07.34 Other psoriatic arthropathies (Hand)	0.698	0.302	0.000
L08 Other local infections of skin and subcutaneous tissue	0.698	0.302	0.000
F11.2 Dependence syndrome	0.697	0.303	0.000
J20-J22 Other acute lower respiratory infections	0.697	0.303	0.000
B99 Other and unspecified infectious diseases	0.696	0.304	0.000
J32.9 Chronic sinusitis, unspecified	0.695	0.305	0.000
J32 Chronic sinusitis	0.695	0.305	0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.695	0.305	0.000
M89 Other disorders of bone	0.694	0.306	0.000
O45 Premature separation of placenta [abruptio placentae]	0.693	0.306	0.000
O33 Maternal care for known or suspected disproportion	0.693	0.306	0.000
O31 Complications specific to multiple gestation	0.693	0.306	0.000
Q60-Q64 Congenital malformations of the urinary system	0.693	0.307	0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.693	0.307	0.000
L12 Pemphigoid	0.692	0.308	0.000
M06.3 Rheumatoid nodule	0.692	0.308	0.000
O63.2 Delayed delivery of second twin, triplet, etc.	0.692	0.308	0.000
M48.9 Spondylopathy, unspecified	0.691	0.309	0.000
M48.8 Other specified spondylopathies	0.691	0.309	0.000
M48.4 Fatigue fracture of vertebra	0.691	0.309	0.000
M48.3 Traumatic spondylopathy	0.691	0.309	0.000
M48.2 Kissing spine	0.691	0.309	0.000
M48.1 Ankylosing hyperostosis [Forestier]	0.691	0.309	0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances	0.689	0.311	0.000
F18 Mental and behavioural disorders due to use of volatile solvents	0.689	0.311	0.000
F16 Mental and behavioural disorders due to use of hallucinogens	0.689	0.311	0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine	0.689	0.311	0.000
F14 Mental and behavioural disorders due to use of cocaine	0.689	0.311	0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics	0.689	0.311	0.000
E03 Other hypothyroidism	0.002	0.314	0.685
F80-F89 Disorders of psychological development	0.686	0.314	0.000
F10.8 Other mental and behavioural disorders	0.686	0.314	0.000
F10.7 Residual and late-onset psychotic disorder	0.686	0.314	0.000
F10.6 Amnesic syndrome	0.686	0.314	0.000
O23 Infections of genito-urinary tract in pregnancy	0.684	0.316	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.684	0.316	0.000
Q35-Q37 Cleft lip and cleft palate	0.684	0.316	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.684	0.316	0.000
L85 Other epidermal thickening	0.683	0.317	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.681	0.319	0.000
J00-J06 Acute upper respiratory infections	0.681	0.319	0.000
O42.2 Premature rupture of membranes, labour delayed by therapy	0.680	0.320	0.000
Q83 Congenital malformations of breast	0.680	0.320	0.000
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more	0.678	0.322	0.000
G60.0 Hereditary motor and sensory neuropathy	0.678	0.322	0.000
O32.2 Maternal care for transverse and oblique lie	0.678	0.322	0.000
O26.8 Other specified pregnancy-related conditions	0.677	0.323	0.000
M60 Myositis	0.677	0.323	0.000
O08 Complications following abortion and ectopic and molar pregnancy	0.677	0.323	0.000
O07 Failed attempted abortion	0.677	0.323	0.000
O06 Unspecified abortion	0.677	0.323	0.000
O05 Other abortion	0.677	0.323	0.000
O01 Hydatidiform mole	0.677	0.323	0.000
A08.4 Viral intestinal infection, unspecified	0.675	0.325	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.675	0.325	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.675	0.325	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.675	0.325	0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.675	0.325	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.675	0.325	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.675	0.325	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.675	0.325	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.675	0.325	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.675	0.325	0.000
O00 Ectopic pregnancy	0.673	0.326	0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.672	0.328	0.000
B85-B89 Pediculosis, acariasis and other infestations	0.671	0.329	0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.671	0.329	0.000
A75-A79 Rickettsioses	0.671	0.329	0.000
A70-A74 Other diseases caused by chlamydiae	0.671	0.329	0.000
A65-A69 Other spirochaetal diseases	0.671	0.329	0.000
A20-A28 Certain zoonotic bacterial diseases	0.671	0.329	0.000
A15-A19 Tuberculosis	0.671	0.329	0.000
L28 Lichen simplex chronicus and prurigo	0.669	0.330	0.000
M07.36 Other psoriatic arthropathies (Lower leg)	0.669	0.331	0.000
A48 Other bacterial diseases, not elsewhere classified	0.668	0.332	0.000
M46.9 Inflammatory spondylopathy, unspecified	0.667	0.333	0.000
L94 Other localised connective tissue disorders	0.665	0.335	0.000
O75.7 Vaginal delivery following previous Caesarean section	0.664	0.336	0.000
M07.6 Other enteropathic arthropathies	0.664	0.336	0.000
M07.5 Arthropathy in ulcerative colitis	0.664	0.336	0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.664	0.336	0.000
M07.2 Psoriatic spondylitis	0.664	0.336	0.000
M07.1 Arthritis mutilans	0.664	0.336	0.000
M07.0 Distal interphalangeal psoriatic arthropathy	0.664	0.336	0.000
Q89 Other congenital malformations, not elsewhere classified	0.662	0.338	0.000
O73.0 Retained placenta, without haemorrhage	0.661	0.339	0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)	0.660	0.339	0.000
M48.05 Spinal stenosis (Thoracolumbar region)	0.660	0.339	0.000
M48.03 Spinal stenosis (Cervicothoracic region)	0.660	0.339	0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)	0.660	0.339	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.660	0.340	0.000
O80-O84 Delivery	0.660	0.340	0.000
O75.9 Complication of labour and delivery, unspecified	0.659	0.340	0.000
O75.5 Delayed delivery after artificial rupture of membranes	0.659	0.340	0.000
O75.4 Other complications of obstetric surgery and procedures	0.659	0.340	0.000
O75.3 Other infection during labour	0.659	0.340	0.000
O75.1 Shock during or following labour and delivery	0.659	0.340	0.000
O04.1 Incomplete, complicated by delayed or excessive haemorrhage	0.659	0.341	0.000
O47.1 False labour at or after 37 completed weeks of gestation	0.657	0.343	0.000
F11.1 Harmful use	0.657	0.343	0.000
G20-G26 Extrapyramidal and movement disorders	0.656	0.344	0.000
Q21 Congenital malformations of cardiac septa	0.655	0.345	0.000
O26.9 Pregnancy-related condition, unspecified	0.654	0.345	0.000
O44 Placenta praevia	0.654	0.346	0.000
O04.4 Incomplete, without complication	0.653	0.347	0.000
A08.1 Acute gastro-enteropathy due to Norwalk agent	0.652	0.348	0.000
L81 Other disorders of pigmentation	0.650	0.350	0.000
L03 Cellulitis	0.650	0.350	0.000
M05 Seropositive rheumatoid arthritis	0.649	0.350	0.000
Q12.0 Congenital cataract	0.649	0.351	0.000
Q39 Congenital malformations of oesophagus	0.646	0.354	0.000
F12 Mental and behavioural disorders due to use of cannabinoids	0.644	0.355	0.000
B65-B83 Helminthiases	0.644	0.356	0.000
L08.9 Local infection of skin and subcutaneous tissue, unspecified	0.643	0.357	0.000
O32.4 Maternal care for high head at term	0.642	0.358	0.000
G91.1 Obstructive hydrocephalus	0.641	0.359	0.000
A80-A89 Viral infections of the central nervous system	0.639	0.361	0.000
B34 Viral infection of unspecified site	0.638	0.362	0.000
L25 Unspecified contact dermatitis	0.637	0.362	0.000
L24 Irritant contact dermatitis	0.637	0.362	0.000
L23 Allergic contact dermatitis	0.637	0.362	0.000
L20 Atopic dermatitis	0.637	0.362	0.000
L26 Exfoliative dermatitis	0.637	0.362	0.000
L22 Diaper [napkin] dermatitis	0.637	0.362	0.000
Q18.1 Preauricular sinus and cyst	0.637	0.363	0.000
O71 Other obstetric trauma	0.636	0.363	0.000
O21 Excessive vomiting in pregnancy	0.635	0.365	0.000
F10.0 Acute intoxication	0.634	0.366	0.000
M48.55 Collapsed vertebra, not elsewhere classified (Thoracolumbar region)	0.633	0.367	0.000
O90 Complications of the puerperium, not elsewhere classified	0.633	0.367	0.000
Q66 Congenital deformities of feet	0.632	0.368	0.000
A44 Bartonellosis	0.632	0.368	0.000
A43 Nocardiosis	0.632	0.368	0.000
A42 Actinomycosis	0.632	0.368	0.000
A39 Meningococcal infection	0.632	0.368	0.000
A37 Whooping cough	0.632	0.368	0.000
A36 Diphtheria	0.632	0.368	0.000
A32 Listeriosis	0.632	0.368	0.000
A31 Infection due to other mycobacteria	0.632	0.368	0.000
A30 Leprosy [Hansen's disease]	0.632	0.368	0.000
A38 Scarlet fever	0.632	0.368	0.000
A35 Other tetanus	0.632	0.368	0.000
A34 Obstetrical tetanus	0.632	0.368	0.000
A33 Tetanus neonatorum	0.632	0.368	0.000
J22 Unspecified acute lower respiratory infection	0.632	0.368	0.000
G98 Other disorders of nervous system, not elsewhere classified	0.630	0.370	0.000
L21 Seborrhoeic dermatitis	0.629	0.371	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.629	0.371	0.000
L92.8 Other granulomatous disorders of skin and subcutaneous tissue	0.629	0.371	0.000
Q00-Q07 Congenital malformations of the nervous system	0.627	0.373	0.000
M07.38 Other psoriatic arthropathies (Other)	0.626	0.373	0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.626	0.373	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.626	0.373	0.000
M07.33 Other psoriatic arthropathies (Forearm)	0.626	0.373	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.626	0.373	0.000
M07.31 Other psoriatic arthropathies (Shoulder region)	0.626	0.373	0.000
O02.9 Abnormal product of conception, unspecified	0.626	0.373	0.000
O02.8 Other specified abnormal products of conception	0.626	0.373	0.000
O32.9 Maternal care for malpresentation of foetus, unspecified	0.625	0.375	0.000
O32.6 Maternal care for compound presentation	0.625	0.375	0.000
O32.3 Maternal care for face, brow and chin presentation	0.625	0.375	0.000
Q76 Congenital malformations of spine and bony thorax	0.625	0.375	0.000
Q45 Other congenital malformations of digestive system	0.625	0.375	0.000
M90 Osteopathies in diseases classified elsewhere	0.624	0.376	0.000
O47.0 False labour before 37 completed weeks of gestation	0.623	0.377	0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.623	0.377	0.000
O29 Complications of anaesthesia during pregnancy	0.622	0.378	0.000
O28 Abnormal findings on antenatal screening of mother	0.622	0.378	0.000
O22 Venous complications in pregnancy	0.622	0.378	0.000
O25 Malnutrition in pregnancy	0.622	0.378	0.000
W50-W64 Exposure to animate mechanical forces	0.622	0.378	0.000
Q82 Other congenital malformations of skin	0.621	0.379	0.000
L29.9 Pruritus, unspecified	0.619	0.381	0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.619	0.381	0.000
O04.8 Complete or unspecified, with other and unspecified complications	0.619	0.381	0.000
O04.7 Complete or unspecified, complicated by embolism	0.619	0.381	0.000
O04.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.619	0.381	0.000
O04.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.619	0.381	0.000
O04.3 Incomplete, with other and unspecified complications	0.619	0.381	0.000
O04.2 Incomplete, complicated by embolism	0.619	0.381	0.000
O04.0 Incomplete, complicated by genital tract and pelvic infection	0.619	0.381	0.000
O69.1 Labour and delivery complicated by cord around neck, with compression	0.618	0.382	0.000
M41 Scoliosis	0.617	0.383	0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere	0.616	0.384	0.000
L87 Transepidermal elimination disorders	0.616	0.384	0.000
L88 Pyoderma gangrenosum	0.616	0.384	0.000
L86 Keratoderma in diseases classified elsewhere	0.616	0.384	0.000
A40 Streptococcal septicaemia	0.616	0.384	0.000
L29.3 Anogenital pruritus, unspecified	0.615	0.385	0.000
L29.1 Pruritus scroti	0.615	0.385	0.000
G94 Other disorders of brain in diseases classified elsewhere	0.615	0.385	0.000
O70 Perineal laceration during delivery	0.615	0.385	0.000
M48.00 Spinal stenosis (Multiple sites in spine)	0.615	0.385	0.000
Q17 Other congenital malformations of ear	0.614	0.386	0.000
Q16 Congenital malformations of ear causing impairment of hearing	0.614	0.386	0.000
Q15 Other congenital malformations of eye	0.614	0.386	0.000
Q14 Congenital malformations of posterior segment of eye	0.614	0.386	0.000
Q13 Congenital malformations of anterior segment of eye	0.614	0.386	0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos	0.614	0.386	0.000
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit	0.614	0.386	0.000
G12 Spinal muscular atrophy and related syndromes	0.614	0.386	0.000
G91.2 Normal-pressure hydrocephalus	0.613	0.387	0.000
L29.8 Other pruritus	0.613	0.387	0.000
M63 Disorders of muscle in diseases classified elsewhere	0.613	0.387	0.000
M61 Calcification and ossification of muscle	0.613	0.387	0.000
M02 Reactive arthropathies	0.612	0.388	0.000
M48.07 Spinal stenosis (Lumbosacral region)	0.611	0.389	0.000
B90-B94 Sequelae of infectious and parasitic diseases	0.610	0.390	0.000
M48.50 Collapsed vertebra, not elsewhere classified (Multiple sites in spine)	0.610	0.390	0.000
M91-M94 Chondropathies	0.609	0.391	0.000
L92.0 Granuloma annulare	0.606	0.394	0.000
L12.1 Cicatricial pemphigoid	0.606	0.394	0.000
M88 Paget's disease of bone [osteitis deformans]	0.606	0.394	0.000
B35-B49 Mycoses	0.605	0.395	0.000
L44 Other papulosquamous disorders	0.605	0.395	0.000
L41 Parapsoriasis	0.605	0.395	0.000
L45 Papulosquamous disorders in diseases classified elsewhere	0.605	0.395	0.000
L42 Pityriasis rosea	0.605	0.395	0.000
F17 Mental and behavioural disorders due to use of tobacco	0.605	0.395	0.000
O30.9 Multiple gestation, unspecified	0.604	0.396	0.000
O30.8 Other multiple gestation	0.604	0.396	0.000
O30.2 Quadruplet pregnancy	0.604	0.396	0.000
O30.1 Triplet pregnancy	0.604	0.396	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.602	0.398	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.599	0.400	0.000
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified	0.599	0.401	0.000
O72.0 Third-stage haemorrhage	0.595	0.404	0.000
G92 Toxic encephalopathy	0.595	0.404	0.000
L95 Vasculitis limited to skin, not elsewhere classified	0.594	0.406	0.000
F11.9 Unspecified mental and behavioural disorder	0.594	0.406	0.000
F11.8 Other mental and behavioural disorders	0.594	0.406	0.000
F11.7 Residual and late-onset psychotic disorder	0.594	0.406	0.000
F11.6 Amnesic syndrome	0.594	0.406	0.000
F11.5 Psychotic disorder	0.594	0.406	0.000
F11.4 Withdrawal state with delirium	0.594	0.406	0.000
F11.3 Withdrawal state	0.594	0.406	0.000
F11.0 Acute intoxication	0.594	0.406	0.000
J02 Acute pharyngitis	0.593	0.407	0.000
L80 Vitiligo	0.593	0.407	0.000
G64 Other disorders of peripheral nervous system	0.592	0.408	0.000
J01 Acute sinusitis	0.591	0.409	0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.591	0.409	0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.591	0.409	0.000
Q84 Other congenital malformations of integument	0.591	0.409	0.000
Q81 Epidermolysis bullosa	0.591	0.409	0.000
Q80 Congenital ichthyosis	0.591	0.409	0.000
O73.1 Retained portions of placenta and membranes, without haemorrhage	0.591	0.409	0.000
O43.1 Malformation of placenta	0.591	0.409	0.000
O20 Haemorrhage in early pregnancy	0.588	0.412	0.000
O69.8 Labour and delivery complicated by other cord complications	0.588	0.412	0.000
M48.56 Collapsed vertebra, not elsewhere classified (Lumbar region)	0.587	0.413	0.000
L05 Pilonidal cyst	0.585	0.415	0.000
A49.2 Haemophilus influenzae infection, unspecified	0.585	0.415	0.000
J09-J18 Influenza and pneumonia	0.584	0.416	0.000
A49.1 Streptococcal infection, unspecified	0.584	0.416	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.583	0.416	0.000
G90.9 Disorder of autonomic nervous system, unspecified	0.583	0.417	0.000
L13 Other bullous disorders	0.582	0.418	0.000
L11 Other acantholytic disorders	0.582	0.418	0.000
L10 Pemphigus	0.582	0.418	0.000
L14 Bullous disorders in diseases classified elsewhere	0.582	0.418	0.000
M86 Osteomyelitis	0.581	0.419	0.000
A07 Other protozoal intestinal diseases	0.581	0.419	0.000
X60-X84 Intentional self-harm	0.581	0.419	0.000
A49.9 Bacterial infection, unspecified	0.580	0.419	0.000
Y57 Other and unspecified drugs and medicaments	0.579	0.421	0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.579	0.421	0.000
Q85 Phakomatoses, not elsewhere classified	0.578	0.422	0.000
L04 Acute lymphadenitis	0.578	0.422	0.000
L01 Impetigo	0.578	0.422	0.000
L00 Staphylococcal scalded skin syndrome	0.578	0.422	0.000
O41 Other disorders of amniotic fluid and membranes	0.578	0.422	0.000
L40.0 Psoriasis vulgaris	0.578	0.422	0.000
G91.8 Other hydrocephalus	0.577	0.423	0.000
G91.3 Posttraumatic hydrocephalus, unspecified	0.577	0.423	0.000
G91.0 Communicating hydrocephalus	0.577	0.423	0.000
L84 Corns and callosities	0.576	0.424	0.000
M89.8 Other specified disorders of bone	0.575	0.425	0.000
F79 Unspecified mental retardation	0.575	0.425	0.000
O36 Maternal care for other known or suspected foetal problems	0.574	0.426	0.000
L03.3 Cellulitis of trunk	0.574	0.426	0.000
M87 Osteonecrosis	0.573	0.427	0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)	0.572	0.427	0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified	0.572	0.428	0.000
J33 Nasal polyp	0.572	0.428	0.000
O43.8 Other placental disorders	0.571	0.429	0.000
M40 Kyphosis and lordosis	0.570	0.429	0.000
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified	0.570	0.430	0.000
M46.8 Other specified inflammatory spondylopathies	0.569	0.430	0.000
M46.5 Other infective spondylopathies	0.569	0.430	0.000
M46.3 Infection of intervertebral disk (pyogenic)	0.569	0.430	0.000
M46.2 Osteomyelitis of vertebra	0.569	0.430	0.000
M46.1 Sacro-iliitis, not elsewhere classified	0.569	0.430	0.000
M46.0 Spinal enthesopathy	0.569	0.430	0.000
M48.59 Collapsed vertebra, not elsewhere classified (Site unspecified)	0.569	0.431	0.000
M48.58 Collapsed vertebra, not elsewhere classified (Sacral and sacrococcygeal region)	0.569	0.431	0.000
M48.57 Collapsed vertebra, not elsewhere classified (Lumbosacral region)	0.569	0.431	0.000
M48.53 Collapsed vertebra, not elsewhere classified (Cervicothoracic region)	0.569	0.431	0.000
M48.52 Collapsed vertebra, not elsewhere classified (Cervical region)	0.569	0.431	0.000
M48.51 Collapsed vertebra, not elsewhere classified (Occipito-atlanto-axial region)	0.569	0.431	0.000
Q43 Other congenital malformations of intestine	0.569	0.431	0.000
G72 Other myopathies	0.568	0.432	0.000
M06.48 Inflammatory polyarthropathy (Other)	0.568	0.432	0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.568	0.432	0.000
M06.46 Inflammatory polyarthropathy (Lower leg)	0.568	0.432	0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.568	0.432	0.000
M06.44 Inflammatory polyarthropathy (Hand)	0.568	0.432	0.000
M06.43 Inflammatory polyarthropathy (Forearm)	0.568	0.432	0.000
M06.42 Inflammatory polyarthropathy (Upper arm)	0.568	0.432	0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.568	0.432	0.000
M11.2 Other chondrocalcinosis	0.567	0.432	0.000
L03.0 Cellulitis of finger and toe	0.568	0.432	0.000
A06 Amoebiasis	0.567	0.433	0.000
A05 Other bacterial foodborne intoxications	0.567	0.433	0.000
A03 Shigellosis	0.567	0.433	0.000
A01 Typhoid and paratyphoid fevers	0.567	0.433	0.000
A00 Cholera	0.567	0.433	0.000
L40.8 Other psoriasis	0.567	0.433	0.000
G03 Meningitis due to other and unspecified causes	0.567	0.433	0.000
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)	0.567	0.433	0.000
L85.9 Epidermal thickening, unspecified	0.566	0.434	0.000
L93 Lupus erythematosus	0.566	0.434	0.000
O69.9 Labour and delivery complicated by cord complication, unspecified	0.565	0.435	0.000
L81.2 Freckles	0.564	0.436	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.563	0.437	0.000
Q78 Other osteochondrodysplasias	0.563	0.437	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.563	0.437	0.000
Q75 Other congenital malformations of skull and face bones	0.563	0.437	0.000
Q74 Other congenital malformations of limb(s)	0.563	0.437	0.000
Q73 Reduction defects of unspecified limb	0.563	0.437	0.000
Q72 Reduction defects of lower limb	0.563	0.437	0.000
Q71 Reduction defects of upper limb	0.563	0.437	0.000
Q70 Syndactyly	0.563	0.437	0.000
Q69 Polydactyly	0.563	0.437	0.000
Q68 Other congenital musculoskeletal deformities	0.563	0.437	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.563	0.437	0.000
B50 Plasmodium falciparum malaria	0.562	0.438	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations