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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs9467704
log Bayes Factor = 146.867
Chromosome 6   position 26,319,486  (GRCh37) Explore rs9467704 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
D64.9 Anaemia, unspecified
1.000 0.000 0.000
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
E83.1 Disorders of iron metabolism
0.000 0.000 1.000
K90.0 Coeliac disease
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
E03 Other hypothyroidism
1.000 0.000 0.000
D60-D64 Aplastic and other anaemias
1.000 0.000 0.000
D64 Other anaemias
1.000 0.000 0.000
M05-M14 Inflammatory polyarthropathies
1.000 0.000 0.000
R31 Unspecified haematuria
0.000 0.000 1.000
M35 Other systemic involvement of connective tissue
0.999 0.001 0.000
M35.0 Sicca syndrome [Sjogren]
0.999 0.001 0.000
H25-H28 Disorders of lens
0.999 0.001 0.000
H26 Other cataract
0.999 0.001 0.000
H26.9 Cataract, unspecified
0.998 0.002 0.000
M06 Other rheumatoid arthritis
0.998 0.002 0.000
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene
0.000 0.003 0.997
E10.3 With ophthalmic complications
0.997 0.003 0.000
M06.9 Rheumatoid arthritis, unspecified
0.997 0.003 0.000
K40 Inguinal hernia
0.000 0.003 0.997
K51 Ulcerative colitis
0.000 0.003 0.997
E70-E90 Metabolic disorders
0.996 0.004 0.000
Chapter XI Diseases of the digestive system
0.028 0.004 0.968
D80-D89 Certain disorders involving the immune mechanism
0.995 0.005 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.995 0.005 0.000
H30-H36 Disorders of choroid and retina
0.995 0.005 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.995 0.005 0.000
K90-K93 Other diseases of the digestive system
0.028 0.006 0.966
E20-E35 Disorders of other endocrine glands
0.993 0.007 0.000
E16 Other disorders of pancreatic internal secretion
0.992 0.008 0.000
K51.9 Ulcerative colitis, unspecified
0.000 0.008 0.992
Chapter II Neoplasms
0.992 0.008 0.000
K40-K46 Hernia
0.001 0.008 0.990
K50-K52 Noninfective enteritis and colitis
0.011 0.010 0.979
N40 Hyperplasia of prostate
0.000 0.010 0.990
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.990 0.010 0.000
D86 Sarcoidosis
0.990 0.010 0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.000 0.011 0.989
E27 Other disorders of adrenal gland
0.989 0.011 0.000
E16.2 Hypoglycaemia, unspecified
0.988 0.012 0.000
E27.1 Primary adrenocortical insufficiency
0.987 0.013 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.987 0.013 0.000
M24 Other specific joint derangements
0.987 0.013 0.000
K40.2 Bilateral inguinal hernia, without obstruction or gangrene
0.000 0.015 0.985
K51.2 Ulcerative (chronic) proctitis
0.000 0.015 0.985
D86.9 Sarcoidosis, unspecified
0.982 0.018 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.979 0.021 0.000
K44 Diaphragmatic hernia
0.000 0.021 0.978
C83.3 Large cell (diffuse)
0.977 0.023 0.000
K92 Other diseases of digestive system
0.000 0.027 0.973
E50-E64 Other nutritional deficiencies
0.973 0.027 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.972 0.028 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.972 0.028 0.000
E78.5 Hyperlipidaemia, unspecified
0.970 0.030 0.000
H36 Retinal disorders in diseases classified elsewhere
0.969 0.031 0.000
H43-H45 Disorders of vitreous body and globe
0.969 0.031 0.000
M15-M19 Arthrosis
0.968 0.032 0.000
M10 Gout
0.968 0.032 0.000
K44.9 Diaphragmatic hernia without obstruction or gangrene
0.000 0.032 0.968
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.967 0.033 0.000
D69 Purpura and other haemorrhagic conditions
0.966 0.034 0.000
M23 Internal derangement of knee
0.960 0.040 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.960 0.040 0.000
M22 Disorders of patella
0.959 0.041 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.954 0.046 0.000
E83 Disorders of mineral metabolism
0.931 0.048 0.021
H36.0 Diabetic retinopathy
0.951 0.049 0.000
M60-M63 Disorders of muscles
0.950 0.050 0.000
M17 Gonarthrosis [arthrosis of knee]
0.948 0.052 0.000
K92.1 Melaena
0.000 0.052 0.948
H43 Disorders of vitreous body
0.947 0.053 0.000
M34 Systemic sclerosis
0.946 0.054 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.945 0.055 0.000
C81 Hodgkin's disease
0.944 0.056 0.000
E53 Deficiency of other B group vitamins
0.943 0.057 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.943 0.057 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.940 0.060 0.000
M50-M54 Other dorsopathies
0.935 0.065 0.000
H43.1 Vitreous haemorrhage
0.932 0.068 0.000
C43 Malignant melanoma of skin
0.932 0.068 0.000
H26.4 After-cataract
0.928 0.072 0.000
K92.0 Haematemesis
0.000 0.073 0.927
K90 Intestinal malabsorption
0.884 0.074 0.042
E10.1 With ketoacidosis
0.924 0.076 0.000
M23.3 Other meniscus derangements
0.924 0.076 0.000
M17.9 Gonarthrosis, unspecified
0.923 0.077 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.921 0.079 0.000
E10.2 With renal complications
0.921 0.079 0.000
H34 Retinal vascular occlusions
0.919 0.081 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.919 0.081 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.918 0.082 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.918 0.082 0.000
E53.8 Deficiency of other specified B group vitamins
0.917 0.083 0.000
E83.5 Disorders of calcium metabolism
0.915 0.085 0.001
M18 Arthrosis of first carpometacarpal joint
0.915 0.085 0.000
M10.9 Gout, unspecified
0.914 0.086 0.000
I73 Other peripheral vascular diseases
0.914 0.086 0.000
M54 Dorsalgia
0.913 0.087 0.000
E11 Non-insulin-dependent diabetes mellitus
0.911 0.089 0.000
K51.4 Pseudopolyposis of colon
0.000 0.097 0.903
D50-D53 Nutritional anaemias
0.903 0.097 0.000
M24.1 Other articular cartilage disorders
0.902 0.098 0.000
H53-H54 Visual disturbances and blindness
0.902 0.098 0.000
M31 Other necrotising vasculopathies
0.899 0.101 0.000
K92.9 Disease of digestive system, unspecified
0.000 0.101 0.899
M62 Other disorders of muscle
0.898 0.102 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.898 0.102 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.895 0.105 0.000
L50-L54 Urticaria and erythema
0.894 0.106 0.000
Chapter IX Diseases of the circulatory system
0.892 0.108 0.000
E78.1 Pure hyperglyceridaemia
0.891 0.109 0.000
E78.6 Lipoprotein deficiency
0.891 0.109 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.888 0.112 0.000
L20-L30 Dermatitis and eczema
0.888 0.112 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.000 0.115 0.885
M54.5 Low back pain
0.883 0.117 0.000
I73.0 Raynaud's syndrome
0.880 0.120 0.000
I77 Other disorders of arteries and arterioles
0.880 0.120 0.000
I73.9 Peripheral vascular disease, unspecified
0.880 0.120 0.000
H54 Blindness and low vision
0.877 0.123 0.000
K92.2 Gastro-intestinal haemorrhage, unspecified
0.000 0.123 0.877
C84 Peripheral and cutaneous T-cell lymphomas
0.874 0.126 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.873 0.127 0.000
D69.6 Thrombocytopenia, unspecified
0.871 0.129 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.870 0.130 0.000
M22.2 Patellofemoral disorders
0.867 0.133 0.000
N40-N51 Diseases of male genital organs
0.000 0.134 0.866
M11 Other crystal arthropathies
0.866 0.134 0.000
K50 Crohn's disease [regional enteritis]
0.001 0.134 0.865
E10.4 With neurological complications
0.866 0.134 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.865 0.135 0.000
C43.3 Malignant melanoma of other and unspecified parts of face
0.863 0.137 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.862 0.138 0.000
E78.4 Other hyperlipidaemia
0.862 0.138 0.000
N42 Other disorders of prostate
0.000 0.138 0.862
C02 Malignant neoplasm of other and unspecified parts of tongue
0.857 0.143 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.855 0.145 0.000
M10.0 Idiopathic gout
0.852 0.148 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.850 0.150 0.000
H31 Other disorders of choroid
0.849 0.151 0.000
M22.3 Other derangements of patella
0.848 0.151 0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral
0.847 0.153 0.000
M13 Other arthritis
0.846 0.154 0.000
Q50-Q56 Congenital malformations of genital organs
0.845 0.155 0.000
E73 Lactose intolerance
0.844 0.156 0.000
D50 Iron deficiency anaemia
0.843 0.157 0.000
M54.1 Radiculopathy
0.842 0.158 0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.841 0.159 0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.841 0.159 0.000
E14 Unspecified diabetes mellitus
0.840 0.160 0.000
C43.4 Malignant melanoma of scalp and neck
0.839 0.161 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.838 0.162 0.000
M54.56 Low back pain (Lumbar region)
0.838 0.162 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.838 0.162 0.000
L30 Other dermatitis
0.834 0.166 0.000
C85.1 B-cell lymphoma, unspecified
0.834 0.166 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.834 0.166 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.831 0.168 0.000
M34.9 Systemic sclerosis, unspecified
0.830 0.170 0.000
C43.5 Malignant melanoma of trunk
0.830 0.170 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.829 0.171 0.000
M62.8 Other specified disorders of muscle
0.827 0.172 0.000
M24.2 Disorder of ligament
0.827 0.173 0.000
D69.4 Other primary thrombocytopenia
0.827 0.173 0.000
M34.1 CR(E)ST syndrome
0.826 0.174 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.826 0.174 0.000
E80.4 Gilbert's syndrome
0.823 0.177 0.000
M54.4 Lumbago with sciatica
0.823 0.177 0.000
E11.3 With ophthalmic complications
0.823 0.177 0.000
C83.7 Burkitt's tumour
0.823 0.177 0.000
E11.9 Without complications
0.821 0.179 0.000
E23 Hypofunction and other disorders of pituitary gland
0.820 0.180 0.000
D50.8 Other iron deficiency anaemias
0.819 0.181 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.819 0.181 0.000
N42.1 Congestion and haemorrhage of prostate
0.000 0.183 0.817
K51.8 Other ulcerative colitis
0.000 0.183 0.817
E84 Cystic fibrosis
0.815 0.185 0.000
H34.2 Other retinal artery occlusions
0.815 0.185 0.000
D86.0 Sarcoidosis of lung
0.814 0.186 0.000
C81.1 Nodular sclerosis
0.813 0.187 0.000
E61 Deficiency of other nutrient elements
0.813 0.187 0.000
M17.1 Other primary gonarthrosis
0.812 0.188 0.000
E10.8 With unspecified complications
0.812 0.188 0.000
Q60-Q64 Congenital malformations of the urinary system
0.810 0.190 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.809 0.191 0.000
C83.0 Small cell (diffuse)
0.806 0.194 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.788 0.195 0.017
L52 Erythema nodosum
0.805 0.195 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.805 0.195 0.000
M24.11 Other articular cartilage disorders (Shoulder region)
0.805 0.195 0.000
M23.9 Internal derangement of knee, unspecified
0.805 0.195 0.000
E21.3 Hyperparathyroidism, unspecified
0.801 0.199 0.000
L30.9 Dermatitis, unspecified
0.801 0.199 0.000
M23.4 Loose body in knee
0.800 0.200 0.000
M10.94 Gout, unspecified (Hand)
0.800 0.200 0.000
L10-L14 Bullous disorders
0.800 0.200 0.000
M18.1 Other primary arthrosis of first carpometacarpal joint
0.800 0.200 0.000
C83.1 Small cleaved cell (diffuse)
0.799 0.201 0.000
K50.1 Crohn's disease of large intestine
0.000 0.203 0.797
C85.7 Other specified types of non-Hodgkin's lymphoma
0.796 0.203 0.000
M13.0 Polyarthritis, unspecified
0.795 0.205 0.000
H26.2 Complicated cataract
0.795 0.205 0.000
E16.1 Other hypoglycaemia
0.795 0.205 0.000
H54.7 Unspecified visual loss
0.793 0.207 0.000
N42.8 Other specified disorders of prostate
0.000 0.207 0.793
M31.6 Other giant cell arteritis
0.792 0.208 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.792 0.208 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.791 0.209 0.000
I77.1 Stricture of artery
0.790 0.210 0.000
H35 Other retinal disorders
0.790 0.210 0.000
L40-L45 Papulosquamous disorders
0.787 0.213 0.000
C02.9 Tongue, unspecified
0.787 0.213 0.000
E10.0 With coma
0.787 0.213 0.000
I77.6 Arteritis, unspecified
0.787 0.213 0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)
0.786 0.214 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.786 0.214 0.000
D84 Other immunodeficiencies
0.785 0.215 0.000
H27 Other disorders of lens
0.785 0.215 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.784 0.216 0.000
E21.0 Primary hyperparathyroidism
0.784 0.216 0.000
D83 Common variable immunodeficiency
0.783 0.217 0.000
Q80-Q89 Other congenital malformations
0.783 0.217 0.000
K51.0 Ulcerative (chronic) enterocolitis
0.000 0.217 0.783
H47.2 Optic atrophy
0.782 0.218 0.000
M00-M03 Infectious arthropathies
0.781 0.219 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.780 0.220 0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.779 0.221 0.000
H26.1 Traumatic cataract
0.779 0.221 0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)
0.779 0.221 0.000
C81.9 Hodgkin's disease, unspecified
0.777 0.223 0.000
E11.0 With coma
0.776 0.224 0.000
I70 Atherosclerosis
0.774 0.226 0.000
E10.6 With other specified complications
0.774 0.226 0.000
C95 Leukaemia of unspecified cell type
0.774 0.226 0.000
D80 Immunodeficiency with predominantly antibody defects
0.773 0.227 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.773 0.227 0.000
I74 Arterial embolism and thrombosis
0.773 0.227 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.772 0.228 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.772 0.228 0.000
M10.90 Gout, unspecified (Multiple sites)
0.771 0.229 0.000
M11.2 Other chondrocalcinosis
0.770 0.230 0.000
H34.8 Other retinal vascular occlusions
0.769 0.231 0.000
M10.07 Idiopathic gout (Ankle and foot)
0.769 0.231 0.000
H54.4 Blindness, one eye
0.768 0.232 0.000
M10.99 Gout, unspecified (Site unspecified)
0.766 0.234 0.000
C81.2 Mixed cellularity
0.766 0.234 0.000
M50 Cervical disk disorders
0.764 0.236 0.000
M60 Myositis
0.764 0.236 0.000
D64.8 Other specified anaemias
0.763 0.237 0.000
C81.0 Lymphocytic predominance
0.763 0.237 0.000
E13 Other specified diabetes mellitus
0.763 0.237 0.000
L27 Dermatitis due to substances taken internally
0.762 0.237 0.000
E14.3 With ophthalmic complications
0.762 0.238 0.000
D69.9 Haemorrhagic condition, unspecified
0.760 0.240 0.000
H46 Optic neuritis
0.758 0.242 0.000
K90.9 Intestinal malabsorption, unspecified
0.741 0.242 0.017
D61 Other aplastic anaemias
0.757 0.243 0.000
D55-D59 Haemolytic anaemias
0.757 0.243 0.000
Chapter V Mental and behavioural disorders
0.757 0.243 0.000
D86.3 Sarcoidosis of skin
0.756 0.244 0.000
N42.9 Disorder of prostate, unspecified
0.000 0.244 0.756
M24.5 Contracture of joint
0.755 0.245 0.000
M24.0 Loose body in joint
0.754 0.246 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.753 0.247 0.000
M22.8 Other disorders of patella
0.753 0.247 0.000
L80 Vitiligo
0.753 0.247 0.000
E10.5 With peripheral circulatory complications
0.752 0.248 0.000
H18 Other disorders of cornea
0.752 0.248 0.000
C84.5 Other and unspecified T-cell lymphomas
0.752 0.248 0.000
M23.5 Chronic instability of knee
0.751 0.249 0.000
D69.0 Allergic purpura
0.749 0.251 0.000
M62.6 Muscle strain
0.749 0.251 0.000
K44.0 Diaphragmatic hernia with obstruction, without gangrene
0.000 0.251 0.749
M34.8 Other forms of systemic sclerosis
0.748 0.252 0.000
D86.8 Sarcoidosis of other and combined sites
0.747 0.253 0.000
M33 Dermatopolymyositis
0.747 0.253 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.745 0.254 0.000
C07 Malignant neoplasm of parotid gland
0.745 0.255 0.000
M23.1 Discoid meniscus (congenital)
0.745 0.255 0.000
H43.8 Other disorders of vitreous body
0.744 0.256 0.000
M23.30 Other meniscus derangements (Multiple sites)
0.743 0.257 0.000
Q00-Q07 Congenital malformations of the nervous system
0.743 0.257 0.000
E06 Thyroiditis
0.742 0.257 0.000
Q39 Congenital malformations of oesophagus
0.740 0.260 0.000
L50 Urticaria
0.738 0.262 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.737 0.263 0.000
E73.9 Lactose intolerance, unspecified
0.735 0.265 0.000
M15 Polyarthrosis
0.734 0.266 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.734 0.266 0.000
E27.2 Addisonian crisis
0.734 0.266 0.000
H47.3 Other disorders of optic disk
0.734 0.266 0.000
M62.80 Other specified disorders of muscle (Multiple sites)
0.734 0.266 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.734 0.266 0.000
L89 Decubitus ulcer
0.734 0.266 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.731 0.269 0.000
M32 Systemic lupus erythematosus
0.731 0.269 0.000
M24.7 Protrusio acetabuli
0.731 0.269 0.000
M54.50 Low back pain (Multiple sites in spine)
0.730 0.270 0.000
M13.00 Polyarthritis, unspecified (Multiple sites)
0.729 0.271 0.000
M06.4 Inflammatory polyarthropathy
0.728 0.272 0.000
H30 Chorioretinal inflammation
0.728 0.272 0.000
H43.9 Disorder of vitreous body, unspecified
0.728 0.272 0.000
C43.9 Malignant melanoma of skin, unspecified
0.728 0.272 0.000
M21 Other acquired deformities of limbs
0.727 0.273 0.000
E53.9 Vitamin B deficiency, unspecified
0.727 0.273 0.000
K51.5 Mucosal proctocolitis
0.000 0.274 0.726
H54.9 Unspecified visual impairment (binocular)
0.726 0.274 0.000
E88 Other metabolic disorders
0.725 0.275 0.000
M14 Arthropathies in other diseases classified elsewhere
0.724 0.276 0.000
E11.1 With ketoacidosis
0.721 0.279 0.000
M54.46 Lumbago with sciatica (Lumbar region)
0.721 0.279 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.720 0.280 0.000
E11.5 With peripheral circulatory complications
0.720 0.280 0.000
M22.0 Recurrent dislocation of patella
0.719 0.280 0.000
H47.0 Disorders of optic nerve, not elsewhere classified
0.719 0.281 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.719 0.281 0.000
C84.0 Mycosis fungoides
0.718 0.282 0.000
E20 Hypoparathyroidism
0.718 0.282 0.000
I77.8 Other specified disorders of arteries and arterioles
0.717 0.283 0.000
D63.8 Anaemia in other chronic diseases classified elsewhere
0.717 0.283 0.000
E10.7 With multiple complications
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.717 0.283 0.000
E03.5 Myxoedema coma
0.717 0.283 0.000
E03.4 Atrophy of thyroid (acquired)
0.717 0.283 0.000
E03.3 Postinfectious hypothyroidism
0.717 0.283 0.000
E03.1 Congenital hypothyroidism without goitre
0.717 0.283 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.717 0.283 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.717 0.283 0.000
D64.4 Congenital dyserythropoietic anaemia
0.717 0.283 0.000
D64.3 Other sideroblastic anaemias
0.717 0.283 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.717 0.283 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.717 0.283 0.000
D64.0 Hereditary sideroblastic anaemia
0.717 0.283 0.000
M12 Other specific arthropathies
0.717 0.283 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.717 0.283 0.000
M08 Juvenile arthritis
0.717 0.283 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.716 0.283 0.000
M35.8 Other specified systemic involvement of connective tissue
0.716 0.283 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.716 0.283 0.000
M35.5 Multifocal fibrosclerosis
0.716 0.283 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.716 0.283 0.000
M35.2 Behcet's disease
0.716 0.283 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.716 0.284 0.000
H26.3 Drug-induced cataract
0.716 0.284 0.000
M06.8 Other specified rheumatoid arthritis
0.715 0.284 0.000
M06.2 Rheumatoid bursitis
0.715 0.284 0.000
M06.1 Adult-onset Still's disease
0.715 0.284 0.000
H35.8 Other specified retinal disorders
0.715 0.285 0.000
K40.4 Unilateral or unspecified inguinal hernia, with gangrene
0.000 0.285 0.715
K40.1 Bilateral inguinal hernia, with gangrene
0.000 0.285 0.715
K51.1 Ulcerative (chronic) ileocolitis
0.000 0.285 0.715
E79 Disorders of purine and pyrimidine metabolism
0.714 0.286 0.000
E77 Disorders of glycoprotein metabolism
0.714 0.286 0.000
E76 Disorders of glycosaminoglycan metabolism
0.714 0.286 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.714 0.286 0.000
E72 Other disorders of amino-acid metabolism
0.714 0.286 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.714 0.286 0.000
E70 Disorders of aromatic amino-acid metabolism
0.714 0.286 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.714 0.286 0.000
D82 Immunodeficiency associated with other major defects
0.714 0.286 0.000
D81 Combined immunodeficiencies
0.714 0.286 0.000
M65-M68 Disorders of synovium and tendon
0.714 0.286 0.000
E15 Nondiabetic hypoglycaemic coma
0.714 0.286 0.000
M86-M90 Other osteopathies
0.714 0.286 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.713 0.287 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.713 0.287 0.000
C94 Other leukaemias of specified cell type
0.713 0.287 0.000
C93 Monocytic leukaemia
0.713 0.287 0.000
C86 Other specified types of T/NK-cell lymphoma
0.713 0.287 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.021 0.287 0.693
E07 Other disorders of thyroid
0.713 0.287 0.000
M24.26 Disorder of ligament (Lower leg)
0.712 0.288 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.712 0.288 0.000
E32 Diseases of thymus
0.712 0.288 0.000
E31 Polyglandular dysfunction
0.712 0.288 0.000
E30 Disorders of puberty, not elsewhere classified
0.712 0.288 0.000
E25 Adrenogenital disorders
0.712 0.288 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.711 0.289 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.711 0.289 0.000
E16.4 Abnormal secretion of gastrin
0.711 0.289 0.000
E16.3 Increased secretion of glucagon
0.711 0.289 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.711 0.289 0.000
L23 Allergic contact dermatitis
0.711 0.289 0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments
0.710 0.290 0.000
C43.6 Malignant melanoma of upper limb, including shoulder
0.710 0.290 0.000
E78.3 Hyperchylomicronaemia
0.710 0.290 0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.709 0.290 0.000
E27.5 Adrenomedullary hyperfunction
0.709 0.291 0.000
E27.0 Other adrenocortical overactivity
0.709 0.291 0.000
M35.7 Hypermobility syndrome
0.709 0.291 0.000
M23.0 Cystic meniscus
0.709 0.291 0.000
M54.47 Lumbago with sciatica (Lumbosacral region)
0.708 0.292 0.000
M54.12 Radiculopathy (Cervical region)
0.708 0.292 0.000
H43.2 Crystalline deposits in vitreous body
0.708 0.292 0.000
C83.6 Undifferentiated (diffuse)
0.707 0.293 0.000
C83.5 Lymphoblastic (diffuse)
0.707 0.293 0.000
C83.4 Immunoblastic (diffuse)
0.707 0.293 0.000
C83.2 Mixed small and large cell (diffuse)
0.707 0.293 0.000
M24.9 Joint derangement, unspecified
0.707 0.293 0.000
M24.6 Ankylosis of joint
0.707 0.293 0.000
L43 Lichen planus
0.707 0.293 0.000
C05 Malignant neoplasm of palate
0.707 0.293 0.000
D62 Acute posthaemorrhagic anaemia
0.707 0.293 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.000 0.294 0.706
E74 Other disorders of carbohydrate metabolism
0.706 0.294 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.705 0.295 0.000
Q35-Q37 Cleft lip and cleft palate
0.702 0.298 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.702 0.298 0.000
E05.8 Other thyrotoxicosis
0.702 0.298 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.702 0.298 0.000
K44.1 Diaphragmatic hernia with gangrene
0.000 0.298 0.701
M54.19 Radiculopathy (Site unspecified)
0.702 0.298 0.000
M11.26 Other chondrocalcinosis (Lower leg)
0.701 0.299 0.000
M06.3 Rheumatoid nodule
0.700 0.299 0.000
E11.6 With other specified complications
0.699 0.301 0.000
C92 Myeloid leukaemia
0.698 0.301 0.000
M62.86 Other specified disorders of muscle (Lower leg)
0.698 0.302 0.000
C13 Malignant neoplasm of hypopharynx
0.698 0.302 0.000
E61.1 Iron deficiency
0.698 0.302 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.698 0.302 0.000
E63 Other nutritional deficiencies
0.698 0.302 0.000
E56 Other vitamin deficiencies
0.698 0.302 0.000
E51 Thiamine deficiency
0.698 0.302 0.000
E50 Vitamin A deficiency
0.698 0.302 0.000
E60 Dietary zinc deficiency
0.698 0.302 0.000
E59 Dietary selenium deficiency
0.698 0.302 0.000
E58 Dietary calcium deficiency
0.698 0.302 0.000
E54 Ascorbic acid deficiency
0.698 0.302 0.000
E52 Niacin deficiency [pellagra]
0.698 0.302 0.000
Q51 Congenital malformations of uterus and cervix
0.697 0.303 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.697 0.303 0.000
C85.0 Lymphosarcoma
0.697 0.303 0.000
D67 Hereditary factor IX deficiency
0.697 0.303 0.000
H44 Disorders of globe
0.697 0.303 0.000
E78.2 Mixed hyperlipidaemia
0.696 0.304 0.000
I78 Diseases of capillaries
0.696 0.304 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.695 0.305 0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.695 0.305 0.000
M10.96 Gout, unspecified (Lower leg)
0.694 0.306 0.000
M10.4 Other secondary gout
0.694 0.306 0.000
M10.3 Gout due to impairment of renal function
0.694 0.306 0.000
M10.2 Drug-induced gout
0.694 0.306 0.000
M10.1 Lead-induced gout
0.694 0.306 0.000
M54.54 Low back pain-Thoracic
0.694 0.306 0.000
M23.99 Internal derangement of knee, unspecified (Unspecified ligament or Unspecified meniscus)
0.693 0.307 0.000
K50.8 Other Crohn's disease
0.000 0.307 0.692
M10.92 Gout, unspecified (Upper arm)
0.693 0.307 0.000
D69.8 Other specified haemorrhagic conditions
0.693 0.307 0.000
D69.2 Other nonthrombocytopenic purpura
0.693 0.307 0.000
D69.1 Qualitative platelet defects
0.693 0.307 0.000
C91 Lymphoid leukaemia
0.692 0.308 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.690 0.310 0.000
H54.6 Unqualified visual loss, one eye
0.690 0.310 0.000
M23.49 Loose body in knee-Unspec lig/men
0.690 0.310 0.000
M31.0 Hypersensitivity angiitis
0.689 0.311 0.000
M22.1 Recurrent subluxation of patella
0.688 0.312 0.000
M22.9 Disorder of patella, unspecified
0.688 0.312 0.000
E23.7 Disorder of pituitary gland, unspecified
0.688 0.312 0.000
C04 Malignant neoplasm of floor of mouth
0.687 0.313 0.000
H34.1 Central retinal artery occlusion
0.687 0.313 0.000
E23.2 Diabetes insipidus
0.685 0.315 0.000
E84.9 Cystic fibrosis, unspecified
0.685 0.315 0.000
K92.8 Other specified diseases of digestive system
0.000 0.316 0.683
L28 Lichen simplex chronicus and prurigo
0.683 0.317 0.000
L53 Other erythematous conditions
0.683 0.317 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.667 0.317 0.015
E83.8 Other disorders of mineral metabolism
0.667 0.317 0.015
E83.2 Disorders of zinc metabolism
0.667 0.317 0.015
E83.0 Disorders of copper metabolism
0.667 0.317 0.015
E29 Testicular dysfunction
0.682 0.318 0.000
M63 Disorders of muscle in diseases classified elsewhere
0.681 0.319 0.000
M61 Calcification and ossification of muscle
0.681 0.319 0.000
D51 Vitamin B12 deficiency anaemia
0.681 0.319 0.000
M17.5 Other secondary gonarthrosis
0.680 0.319 0.000
M21.0 Valgus deformity, not elsewhere classified
0.680 0.320 0.000
M17.4 Other secondary gonarthrosis, bilateral
0.680 0.320 0.000
M17.2 Posttraumatic gonarthrosis, bilateral
0.680 0.320 0.000
K40.0 Bilateral inguinal hernia, with obstruction, without gangrene
0.000 0.320 0.680
M23.6 Other spontaneous disruption of ligament(s) of knee
0.679 0.321 0.000
E83.4 Disorders of magnesium metabolism
0.671 0.321 0.008

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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