TreeWAS – Variant ID: rs960709

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
H60.9 Otitis externa, unspecified	0.000	0.977	0.023
H60 Otitis externa	0.000	0.978	0.022
H61.8 Other specified disorders of external ear	0.000	0.980	0.020
H60.3 Other infective otitis externa	0.000	0.982	0.018
H60-H62 Diseases of external ear	0.000	0.982	0.018
H61 Other disorders of external ear	0.000	0.982	0.018
H60.4 Cholesteatoma of external ear	0.000	0.982	0.018
H60.5 Acute otitis externa, non-infective	0.000	0.982	0.017
H60.8 Other otitis externa	0.000	0.983	0.017
S83.6 Sprain and strain of other and unspecified parts of knee	0.017	0.983	0.000
H60.1 Cellulitis of external ear	0.000	0.983	0.017
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.016	0.984	0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.016	0.984	0.000
H60.2 Malignant otitis externa	0.000	0.984	0.016
H60.0 Abscess of external ear	0.000	0.984	0.016
H61.3 Acquired stenosis of external ear canal	0.000	0.985	0.015
S83.2 Tear of meniscus, current	0.015	0.985	0.000
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.014	0.986	0.000
H61.1 Non-infective disorders of pinna	0.000	0.986	0.013
E27.1 Primary adrenocortical insufficiency	0.013	0.987	0.000
H62 Disorders of external ear in diseases classified elsewhere	0.000	0.987	0.013
S83.0 Dislocation of patella	0.013	0.987	0.000
E27 Other disorders of adrenal gland	0.013	0.987	0.000
H61.9 Disorder of external ear, unspecified	0.000	0.988	0.012
S83.3 Tear of articular cartilage of knee, current	0.012	0.988	0.000
S83.1 Dislocation of knee	0.012	0.988	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.012	0.988	0.000
E27.9 Disorder of adrenal gland, unspecified	0.012	0.988	0.000
S83.7 Injury to multiple structures of knee	0.011	0.988	0.000
H61.2 Impacted cerumen	0.000	0.989	0.011
H61.0 Perichondritis of external ear	0.000	0.989	0.011
E27.2 Addisonian crisis	0.010	0.990	0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.000	0.990	0.010
H62.8 Other disorders of external ear in diseases classified elsewhere	0.000	0.990	0.009
H62.4 Otitis externa in other diseases classified elsewhere	0.000	0.990	0.009
H62.3 Otitis externa in other infectious and parasitic diseases classified elsewhere	0.000	0.990	0.009
H62.2 Otitis externa in mycoses	0.000	0.990	0.009
H62.1 Otitis externa in viral diseases classified elsewhere	0.000	0.990	0.009
E27.5 Adrenomedullary hyperfunction	0.009	0.991	0.000
E27.0 Other adrenocortical overactivity	0.009	0.991	0.000
H62.0 Otitis externa in bacterial diseases classified elsewhere	0.000	0.991	0.009
E27.3 Drug-induced adrenocortical insufficiency	0.009	0.991	0.000
E20-E35 Disorders of other endocrine glands	0.008	0.992	0.000
E24 Cushing's syndrome	0.008	0.992	0.000
E23 Hypofunction and other disorders of pituitary gland	0.008	0.992	0.000
E83.1 Disorders of iron metabolism	0.000	0.992	0.008
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.008	0.992	0.000
E22 Hyperfunction of pituitary gland	0.007	0.993	0.000
E24.0 Pituitary-dependent Cushing's disease	0.007	0.993	0.000
E23.0 Hypopituitarism	0.007	0.993	0.000
E23.2 Diabetes insipidus	0.007	0.993	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.007	0.993	0.000
E27.8 Other specified disorders of adrenal gland	0.007	0.993	0.000
Q82 Other congenital malformations of skin	0.007	0.993	0.000
E24.9 Cushing's syndrome, unspecified	0.007	0.993	0.000
E20 Hypoparathyroidism	0.006	0.993	0.000
E83.3 Disorders of phosphorus metabolism	0.000	0.994	0.006
Q82.8 Other specified congenital malformations of skin	0.006	0.994	0.000
Q79.6 Ehlers-Danlos syndrome	0.006	0.994	0.000
Q79.8 Other congenital malformations of musculoskeletal system	0.006	0.994	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.006	0.994	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.006	0.994	0.000
E32 Diseases of thymus	0.006	0.994	0.000
E31 Polyglandular dysfunction	0.006	0.994	0.000
E30 Disorders of puberty, not elsewhere classified	0.006	0.994	0.000
E26 Hyperaldosteronism	0.006	0.994	0.000
E25 Adrenogenital disorders	0.006	0.994	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.006	0.994	0.000
Q82.5 Congenital nonneoplastic naevus	0.006	0.994	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.006	0.994	0.000
E24.2 Drug-induced Cushing's syndrome	0.006	0.994	0.000
Q82.0 Hereditary lymphoedema	0.006	0.994	0.000
E24.8 Other Cushing's syndrome	0.006	0.994	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.006	0.994	0.000
E24.3 Ectopic ACTH syndrome	0.006	0.994	0.000
E24.1 Nelson's syndrome	0.006	0.994	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.006	0.994	0.000
E23.1 Drug-induced hypopituitarism	0.006	0.994	0.000
Q78 Other osteochondrodysplasias	0.006	0.994	0.000
Q24 Other congenital malformations of heart	0.006	0.994	0.000
E23.6 Other disorders of pituitary gland	0.006	0.994	0.000
Q79.0 Congenital diaphragmatic hernia	0.006	0.994	0.000
Q80-Q89 Other congenital malformations	0.006	0.994	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.006	0.994	0.000
Q78.0 Osteogenesis imperfecta	0.006	0.994	0.000
Q60-Q64 Congenital malformations of the urinary system	0.006	0.994	0.000
Q18 Other congenital malformations of face and neck	0.006	0.994	0.000
E83 Disorders of mineral metabolism	0.000	0.994	0.006
E22.9 Hyperfunction of pituitary gland, unspecified	0.005	0.994	0.000
E22.8 Other hyperfunction of pituitary gland	0.005	0.994	0.000
Q18.1 Preauricular sinus and cyst	0.006	0.994	0.000
Q24.8 Other specified congenital malformations of heart	0.006	0.994	0.000
Q24.5 Malformation of coronary vessels	0.005	0.995	0.000
E29 Testicular dysfunction	0.005	0.995	0.000
E23.7 Disorder of pituitary gland, unspecified	0.005	0.995	0.000
E22.1 Hyperprolactinaemia	0.005	0.995	0.000
D04.3 Skin of other and unspecified parts of face	0.005	0.995	0.000
E20.9 Hypoparathyroidism, unspecified	0.005	0.995	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.005	0.995	0.000
Q15 Other congenital malformations of eye	0.005	0.995	0.000
Q40 Other congenital malformations of upper alimentary tract	0.005	0.995	0.000
Q79.9 Congenital malformation of musculoskeletal system, unspecified	0.005	0.995	0.000
Q79.5 Other congenital malformations of abdominal wall	0.005	0.995	0.000
Q79.4 Prune belly syndrome	0.005	0.995	0.000
Q79.3 Gastroschisis	0.005	0.995	0.000
Q79.2 Exomphalos	0.005	0.995	0.000
Q79.1 Other congenital malformations of diaphragm	0.005	0.995	0.000
Q61 Cystic kidney disease	0.005	0.995	0.000
Q82.9 Congenital malformation of skin, unspecified	0.005	0.995	0.000
Q82.4 Ectodermal dysplasia (anhidrotic)	0.005	0.995	0.000
Q82.3 Incontinentia pigmenti	0.005	0.995	0.000
Q82.1 Xeroderma pigmentosum	0.005	0.995	0.000
E83.4 Disorders of magnesium metabolism	0.000	0.995	0.005
S06.6 Traumatic subarachnoid haemorrhage	0.000	0.995	0.005
Q82.2 Mastocytosis	0.005	0.995	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.005	0.995	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.005	0.995	0.000
Q35-Q37 Cleft lip and cleft palate	0.005	0.995	0.000
E20.8 Other hypoparathyroidism	0.005	0.995	0.000
E20.1 Pseudohypoparathyroidism	0.005	0.995	0.000
E20.0 Idiopathic hypoparathyroidism	0.005	0.995	0.000
Q12 Congenital lens malformations	0.005	0.995	0.000
Q24.4 Congenital subaortic stenosis	0.005	0.995	0.000
Q39 Congenital malformations of oesophagus	0.005	0.995	0.000
D52.9 Folate deficiency anaemia, unspecified	0.005	0.995	0.000
J33.9 Nasal polyp, unspecified	0.000	0.995	0.005
M35.0 Sicca syndrome [Sjogren]	0.005	0.995	0.000
Q68 Other congenital musculoskeletal deformities	0.005	0.995	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.005	0.995	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.005	0.995	0.000
Q15.0 Congenital glaucoma	0.005	0.995	0.000
E25.9 Adrenogenital disorder, unspecified	0.004	0.995	0.000
E25.8 Other adrenogenital disorders	0.004	0.995	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.004	0.995	0.000
E30.9 Disorder of puberty, unspecified	0.004	0.995	0.000
E30.8 Other disorders of puberty	0.004	0.995	0.000
E30.1 Precocious puberty	0.004	0.995	0.000
E30.0 Delayed puberty	0.004	0.995	0.000
E31.9 Polyglandular dysfunction, unspecified	0.004	0.995	0.000
E31.8 Other polyglandular dysfunction	0.004	0.995	0.000
E31.1 Polyglandular hyperfunction	0.004	0.995	0.000
E31.0 Autoimmune polyglandular failure	0.004	0.995	0.000
E32.9 Disease of thymus, unspecified	0.004	0.995	0.000
E32.8 Other diseases of thymus	0.004	0.995	0.000
E32.1 Abscess of thymus	0.004	0.995	0.000
E32.0 Persistent hyperplasia of thymus	0.004	0.995	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.004	0.995	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.004	0.995	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.004	0.995	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.005	0.995	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.005	0.995	0.000
E26.9 Hyperaldosteronism, unspecified	0.005	0.995	0.000
E26.8 Other hyperaldosteronism	0.005	0.995	0.000
E26.1 Secondary hyperaldosteronism	0.005	0.995	0.000
H66.9 Otitis media, unspecified	0.000	0.995	0.005
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.005	0.995	0.000
Q75 Other congenital malformations of skull and face bones	0.005	0.995	0.000
Q73 Reduction defects of unspecified limb	0.005	0.995	0.000
Q72 Reduction defects of lower limb	0.005	0.995	0.000
Q71 Reduction defects of upper limb	0.005	0.995	0.000
Q70 Syndactyly	0.005	0.995	0.000
Q69 Polydactyly	0.005	0.995	0.000
E26.0 Primary hyperaldosteronism	0.005	0.995	0.000
Q61.3 Polycystic kidney, unspecified	0.005	0.995	0.000
Q39.4 Oesophageal web	0.005	0.995	0.000
Q40.3 Congenital malformation of stomach, unspecified	0.005	0.995	0.000
Q14 Congenital malformations of posterior segment of eye	0.004	0.995	0.000
Q24.0 Dextrocardia	0.004	0.995	0.000
Q16 Congenital malformations of ear causing impairment of hearing	0.004	0.995	0.000
Q13 Congenital malformations of anterior segment of eye	0.004	0.995	0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos	0.004	0.995	0.000
Q61.4 Renal dysplasia	0.004	0.995	0.000
Q24.6 Congenital heart block	0.004	0.996	0.000
Q24.3 Pulmonary infundibular stenosis	0.004	0.996	0.000
Q24.2 Cor triatriatum	0.004	0.996	0.000
Q24.1 Levocardia	0.004	0.996	0.000
Q40.1 Congenital hiatus hernia	0.004	0.996	0.000
Q78.9 Osteochondrodysplasia, unspecified	0.004	0.996	0.000
Q78.8 Other specified osteochondrodysplasias	0.004	0.996	0.000
Q78.6 Multiple congenital exostoses	0.004	0.996	0.000
Q78.5 Metaphyseal dysplasia	0.004	0.996	0.000
Q78.4 Enchondromatosis	0.004	0.996	0.000
Q78.3 Progressive diaphyseal dysplasia	0.004	0.996	0.000
Q78.2 Osteopetrosis	0.004	0.996	0.000
Q78.1 Polyostotic fibrous dysplasia	0.004	0.996	0.000
Q00-Q07 Congenital malformations of the nervous system	0.004	0.996	0.000
Q61.9 Cystic kidney disease, unspecified	0.004	0.996	0.000
Q45 Other congenital malformations of digestive system	0.004	0.996	0.000
G82.5 Tetraplegia, unspecified	0.004	0.996	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.004	0.996	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.004	0.996	0.000
Q66 Congenital deformities of feet	0.004	0.996	0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.004	0.996	0.000
Q84 Other congenital malformations of integument	0.004	0.996	0.000
Q81 Epidermolysis bullosa	0.004	0.996	0.000
Q80 Congenital ichthyosis	0.004	0.996	0.000
Q28 Other congenital malformations of circulatory system	0.004	0.996	0.000
Q18.9 Congenital malformation of face and neck, unspecified	0.004	0.996	0.000
Q18.8 Other specified congenital malformations of face and neck	0.004	0.996	0.000
Q18.7 Microcheilia	0.004	0.996	0.000
Q18.6 Macrocheilia	0.004	0.996	0.000
Q18.5 Microstomia	0.004	0.996	0.000
Q18.4 Macrostomia	0.004	0.996	0.000
Q18.3 Webbing of neck	0.004	0.996	0.000
Q18.2 Other branchial cleft malformations	0.004	0.996	0.000
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit	0.004	0.996	0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.004	0.996	0.000
Q99 Other chromosome abnormalities, not elsewhere classified	0.004	0.996	0.000
E83.9 Disorder of mineral metabolism, unspecified	0.000	0.996	0.004
E83.8 Other disorders of mineral metabolism	0.000	0.996	0.004
E83.2 Disorders of zinc metabolism	0.000	0.996	0.004
E83.0 Disorders of copper metabolism	0.000	0.996	0.004
Q64 Other congenital malformations of urinary system	0.004	0.996	0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.004	0.996	0.000
Q43 Other congenital malformations of intestine	0.004	0.996	0.000
E29.9 Testicular dysfunction, unspecified	0.004	0.996	0.000
E29.8 Other testicular dysfunction	0.004	0.996	0.000
E29.0 Testicular hyperfunction	0.004	0.996	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.004	0.996	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.004	0.996	0.000
E34 Other endocrine disorders	0.004	0.996	0.000
Q21 Congenital malformations of cardiac septa	0.004	0.996	0.000
Q74 Other congenital malformations of limb(s)	0.004	0.996	0.000
Q12.0 Congenital cataract	0.004	0.996	0.000
Q18.0 Sinus, fistula and cyst of branchial cleft	0.004	0.996	0.000
Q17 Other congenital malformations of ear	0.004	0.996	0.000
Q37 Cleft palate with cleft lip	0.004	0.996	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.000	0.996	0.004
E22.0 Acromegaly and pituitary gigantism	0.004	0.996	0.000
Q26 Congenital malformations of great veins	0.004	0.996	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.004	0.996	0.000
E28 Ovarian dysfunction	0.004	0.996	0.000
Q15.9 Congenital malformation of eye, unspecified	0.004	0.996	0.000
Q15.8 Other specified congenital malformations of eye	0.004	0.996	0.000
Q40.9 Congenital malformation of upper alimentary tract, unspecified	0.004	0.996	0.000
Q40.8 Other specified congenital malformations of upper alimentary tract	0.004	0.996	0.000
Q40.0 Congenital hypertrophic pyloric stenosis	0.004	0.996	0.000
Q63 Other congenital malformations of kidney	0.004	0.996	0.000
Q83 Congenital malformations of breast	0.004	0.996	0.000
Q44.6 Cystic disease of liver	0.004	0.996	0.000
Q60.2 Renal agenesis, unspecified	0.004	0.996	0.000
Q61.8 Other cystic kidney diseases	0.004	0.996	0.000
Q61.1 Polycystic kidney, infantile type	0.004	0.996	0.000
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.000	0.996	0.004
H74.3 Other acquired abnormalities of ear ossicles	0.000	0.996	0.004
Q40.2 Other specified congenital malformations of stomach	0.004	0.996	0.000
Q61.0 Congenital single renal cyst	0.004	0.996	0.000
Q65 Congenital deformities of hip	0.004	0.996	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.004	0.996	0.000
E21.4 Other specified disorders of parathyroid gland	0.004	0.996	0.000
E21.2 Other hyperparathyroidism	0.004	0.996	0.000
Q60.0 Renal agenesis, unilateral	0.004	0.996	0.000
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified	0.004	0.996	0.000
Q96 Turner's syndrome	0.004	0.996	0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified	0.004	0.996	0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified	0.004	0.996	0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified	0.004	0.996	0.000
Q91 Edwards' syndrome and Patau's syndrome	0.004	0.996	0.000
Q90 Down's syndrome	0.004	0.996	0.000
Q24.9 Congenital malformation of the heart, unspecified	0.004	0.996	0.000
Q36 Cleft lip	0.004	0.996	0.000
Q35 Cleft palate	0.004	0.996	0.000
H72 Perforation of tympanic membrane	0.000	0.996	0.004
Q68.8 Other specified congenital musculoskeletal deformities	0.004	0.996	0.000
H66 Suppurative and unspecified otitis media	0.000	0.996	0.004
Q12.9 Congenital lens malformation, unspecified	0.004	0.996	0.000
Q12.8 Other congenital lens malformations	0.004	0.996	0.000
Q12.4 Spherophakia	0.004	0.996	0.000
Q12.3 Congenital aphakia	0.004	0.996	0.000
Q12.2 Coloboma of lens	0.004	0.996	0.000
Q12.1 Congenital displaced lens	0.004	0.996	0.000
Q99.8 Other specified chromosome abnormalities	0.004	0.996	0.000
Chapter VIII Diseases of the ear and mastoid process	0.000	0.996	0.004
G57.6 Lesion of plantar nerve	0.000	0.996	0.004
Q43.1 Hirschsprung's disease	0.004	0.996	0.000
H65-H75 Diseases of middle ear and mastoid	0.000	0.996	0.004
Q39.9 Congenital malformation of oesophagus, unspecified	0.004	0.996	0.000
Q39.8 Other congenital malformations of oesophagus	0.004	0.996	0.000
Q39.5 Congenital dilatation of oesophagus	0.004	0.996	0.000
Q39.3 Congenital stenosis and stricture of oesophagus	0.004	0.996	0.000
Q39.2 Congenital tracheooesophageal fistula without atresia	0.004	0.996	0.000
Q39.1 Atresia of oesophagus with tracheooesophageal fistula	0.004	0.996	0.000
Q39.0 Atresia of oesophagus without fistula	0.004	0.996	0.000
Q21.1 Atrial septal defect	0.004	0.996	0.000
Q68.5 Congenital bowing of long bones of leg, unspecified	0.003	0.996	0.000
Q68.4 Congenital bowing of tibia and fibula	0.003	0.996	0.000
Q68.3 Congenital bowing of femur	0.003	0.996	0.000
Q68.2 Congenital deformity of knee	0.003	0.996	0.000
Q68.1 Congenital deformity of hand	0.003	0.996	0.000
Q68.0 Congenital deformity of sternocleidomastoid muscle	0.003	0.996	0.000
Q60.6 Potter's syndrome	0.004	0.996	0.000
Q60.5 Renal hypoplasia, unspecified	0.004	0.996	0.000
Q60.4 Renal hypoplasia, bilateral	0.004	0.996	0.000
Q60.3 Renal hypoplasia, unilateral	0.004	0.996	0.000
Q60.1 Renal agenesis, bilateral	0.004	0.996	0.000
G82 Paraplegia and tetraplegia	0.004	0.996	0.000
Q34 Other congenital malformations of respiratory system	0.003	0.996	0.000
Q33 Congenital malformations of lung	0.003	0.996	0.000
Q32 Congenital malformations of trachea and bronchus	0.003	0.996	0.000
Q31 Congenital malformations of larynx	0.003	0.996	0.000
Q30 Congenital malformations of nose	0.003	0.996	0.000
Q66.3 Other congenital varus deformities of feet	0.004	0.996	0.000
Q67.5 Congenital deformity of spine	0.003	0.996	0.000
Q44.7 Other congenital malformations of liver	0.003	0.996	0.000
Q44.5 Other congenital malformations of bile ducts	0.003	0.996	0.000
Q44.4 Choledochal cyst	0.003	0.996	0.000
Q44.3 Congenital stenosis and stricture of bile ducts	0.003	0.996	0.000
Q44.2 Atresia of bile ducts	0.003	0.996	0.000
Q44.1 Other congenital malformations of gallbladder	0.003	0.996	0.000
Q44.0 Agenesis, aplasia and hypoplasia of gallbladder	0.003	0.996	0.000
Q67.8 Other congenital deformities of chest	0.003	0.996	0.000
Q67.7 Pectus carinatum	0.003	0.996	0.000
Q67.6 Pectus excavatum	0.003	0.996	0.000
Q67.4 Other congenital deformities of skull, face and jaw	0.003	0.996	0.000
Q67.3 Plagiocephaly	0.003	0.996	0.000
Q67.2 Dolichocephaly	0.003	0.996	0.000
Q67.1 Compression facies	0.003	0.996	0.000
Q67.0 Facial asymmetry	0.003	0.996	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.004	0.996	0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.003	0.996	0.000
Q69.9 Polydactyly, unspecified	0.003	0.996	0.000
Q69.2 Accessory toe(s)	0.003	0.996	0.000
Q69.1 Accessory thumb(s)	0.003	0.996	0.000
Q69.0 Accessory finger(s)	0.003	0.996	0.000
Q70.9 Syndactyly, unspecified	0.003	0.996	0.000
Q70.4 Polysyndactyly	0.003	0.996	0.000
Q70.3 Webbed toes	0.003	0.996	0.000
Q70.2 Fused toes	0.003	0.996	0.000
Q70.1 Webbed fingers	0.003	0.996	0.000
Q70.0 Fused fingers	0.003	0.996	0.000
Q71.9 Reduction defect of upper limb, unspecified	0.003	0.996	0.000
Q71.8 Other reduction defects of upper limb(s)	0.003	0.996	0.000
Q71.6 Lobster-claw hand	0.003	0.996	0.000
Q71.5 Longitudinal reduction defect of ulna	0.003	0.996	0.000
Q71.4 Longitudinal reduction defect of radius	0.003	0.996	0.000
Q71.3 Congenital absence of hand and finger(s)	0.003	0.996	0.000
Q71.2 Congenital absence of both forearm and hand	0.003	0.996	0.000
Q71.1 Congenital absence of upper arm and forearm with hand present	0.003	0.996	0.000
Q71.0 Congenital complete absence of upper limb(s)	0.003	0.996	0.000
Q72.9 Reduction defect of lower limb, unspecified	0.003	0.996	0.000
Q72.8 Other reduction defects of lower limb(s)	0.003	0.996	0.000
Q72.7 Split foot	0.003	0.996	0.000
Q72.6 Longitudinal reduction defect of fibula	0.003	0.996	0.000
Q72.5 Longitudinal reduction defect of tibia	0.003	0.996	0.000
Q72.4 Longitudinal reduction defect of femur	0.003	0.996	0.000
Q72.3 Congenital absence of foot and toe(s)	0.003	0.996	0.000
Q72.2 Congenital absence of both lower leg and foot	0.003	0.996	0.000
Q72.1 Congenital absence of thigh and lower leg with foot present	0.003	0.996	0.000
Q72.0 Congenital complete absence of lower limb(s)	0.003	0.996	0.000
Q73.8 Other reduction defects of unspecified limb(s)	0.003	0.996	0.000
Q73.1 Phocomelia, unspecified limb(s)	0.003	0.996	0.000
Q73.0 Congenital absence of unspecified limb(s)	0.003	0.996	0.000
Q75.9 Congenital malformation of skull and face bones, unspecified	0.003	0.996	0.000
Q75.8 Other specified congenital malformations of skull and face bones	0.003	0.996	0.000
Q75.5 Oculomandibular dysostosis	0.003	0.996	0.000
Q75.4 Mandibulofacial dysostosis	0.003	0.996	0.000
Q75.3 Macrocephaly	0.003	0.996	0.000
Q75.2 Hypertelorism	0.003	0.996	0.000
Q75.1 Craniofacial dysostosis	0.003	0.996	0.000
Q75.0 Craniosynostosis	0.003	0.996	0.000
Q77.9 Osteochondrodysplasia with defects of growth of tubular bones and spine, unspecified	0.003	0.996	0.000
Q77.8 Other osteochondrodysplasia with defects of growth of tubular bones and spine	0.003	0.996	0.000
Q77.7 Spondyloepiphyseal dysplasia	0.003	0.996	0.000
Q77.6 Chondroectodermal dysplasia	0.003	0.996	0.000
Q77.5 Diastrophic dysplasia	0.003	0.996	0.000
Q77.4 Achondroplasia	0.003	0.996	0.000
Q77.3 Chondrodysplasia punctata	0.003	0.996	0.000
Q77.2 Short rib syndrome	0.003	0.996	0.000
Q77.1 Thanatophoric short stature	0.003	0.996	0.000
Q77.0 Achondrogenesis	0.003	0.996	0.000
H74 Other disorders of middle ear and mastoid	0.000	0.996	0.004
Q14.1 Congenital malformation of retina	0.003	0.996	0.000
Q61.2 Polycystic kidney, adult type	0.004	0.996	0.000
Q28.3 Other malformations of cerebral vessels	0.003	0.996	0.000
Q28.0 Arteriovenous malformation of precerebral vessels	0.003	0.996	0.000
Q14.9 Congenital malformation of posterior segment of eye, unspecified	0.003	0.996	0.000
Q14.8 Other congenital malformations of posterior segment of eye	0.003	0.996	0.000
Q14.3 Congenital malformation of choroid	0.003	0.996	0.000
Q14.2 Congenital malformation of optic disk	0.003	0.996	0.000
Q14.0 Congenital malformation of vitreous humour	0.003	0.996	0.000
Q21.9 Congenital malformation of cardiac septum, unspecified	0.003	0.996	0.000
Q87.8 Other specified congenital malformation syndromes, not elsewhere classified	0.003	0.996	0.000
Q66.0 Talipes equinovarus	0.003	0.996	0.000
Q11.3 Macrophthalmos	0.003	0.996	0.000
Q11.2 Microphthalmos	0.003	0.996	0.000
Q11.1 Other anophthalmos	0.003	0.996	0.000
Q11.0 Cystic eyeball	0.003	0.996	0.000
Q13.9 Congenital malformation of anterior segment of eye, unspecified	0.003	0.996	0.000
Q13.8 Other congenital malformations of anterior segment of eye	0.003	0.996	0.000
Q13.5 Blue sclera	0.003	0.996	0.000
Q13.4 Other congenital corneal malformations	0.003	0.996	0.000
Q13.3 Congenital corneal opacity	0.003	0.996	0.000
Q13.2 Other congenital malformations of iris	0.003	0.996	0.000
Q13.1 Absence of iris	0.003	0.996	0.000
Q13.0 Coloboma of iris	0.003	0.996	0.000
Q16.9 Congenital malformation of ear causing impairment of hearing, unspecified	0.003	0.996	0.000
Q16.5 Congenital malformation of inner ear	0.003	0.996	0.000
Q16.4 Other congenital malformations of middle ear	0.003	0.996	0.000
Q16.3 Congenital malformation of ear ossicles	0.003	0.996	0.000
Q16.2 Absence of eustachian tube	0.003	0.996	0.000
Q16.1 Congenital absence, atresia and stricture of auditory canal (external)	0.003	0.996	0.000
Q16.0 Congenital absence of (ear) auricle	0.003	0.996	0.000
Q85 Phakomatoses, not elsewhere classified	0.003	0.996	0.000
G82.1 Spastic paraplegia	0.003	0.996	0.000
H66.4 Suppurative otitis media, unspecified	0.000	0.996	0.003
Q37.9 Unspecified cleft palate with unilateral cleft lip	0.003	0.996	0.000
Q66.7 Pes cavus	0.003	0.996	0.000
Q07 Other congenital malformations of nervous system	0.003	0.996	0.000
H74.1 Adhesive middle ear disease	0.000	0.997	0.003
Q45.8 Other specified congenital malformations of digestive system	0.003	0.997	0.000
Q76 Congenital malformations of spine and bony thorax	0.003	0.997	0.000
Q63.2 Ectopic kidney	0.003	0.997	0.000
Q06 Other congenital malformations of spinal cord	0.003	0.997	0.000
Q01 Encephalocele	0.003	0.997	0.000
Q00 Anencephaly and similar malformations	0.003	0.997	0.000
Q02 Microcephaly	0.003	0.997	0.000
E29.1 Testicular hypofunction	0.003	0.997	0.000
Q89 Other congenital malformations, not elsewhere classified	0.003	0.997	0.000
Q43.3 Congenital malformations of intestinal fixation	0.003	0.997	0.000
Q45.9 Congenital malformation of digestive system, unspecified	0.003	0.997	0.000
Q45.3 Other congenital malformations of pancreas and pancreatic duct	0.003	0.997	0.000
Q45.2 Congenital pancreatic cyst	0.003	0.997	0.000
Q45.1 Annular pancreas	0.003	0.997	0.000
Q45.0 Agenesis, aplasia and hypoplasia of pancreas	0.003	0.997	0.000
R29.6 Tendency to fall, not elsewhere classified	0.000	0.997	0.003
Q41.9 Congenital absence, atresia and stenosis of small intestine, part unspecified	0.003	0.997	0.000
Q41.8 Congenital absence, atresia and stenosis of other specified parts of small intestine	0.003	0.997	0.000
Q41.2 Congenital absence, atresia and stenosis of ileum	0.003	0.997	0.000
Q41.1 Congenital absence, atresia and stenosis of jejunum	0.003	0.997	0.000
Q41.0 Congenital absence, atresia and stenosis of duodenum	0.003	0.997	0.000
Q42.9 Congenital absence, atresia and stenosis of large intestine, part unspecified	0.003	0.997	0.000
Q42.8 Congenital absence, atresia and stenosis of other parts of large intestine	0.003	0.997	0.000
Q42.3 Congenital absence, atresia and stenosis of anus without fistula	0.003	0.997	0.000
Q42.2 Congenital absence, atresia and stenosis of anus with fistula	0.003	0.997	0.000
Q42.1 Congenital absence, atresia and stenosis of rectum without fistula	0.003	0.997	0.000
Q42.0 Congenital absence, atresia and stenosis of rectum with fistula	0.003	0.997	0.000
Q63.1 Lobulated, fused and horseshoe kidney	0.003	0.997	0.000
E21.3 Hyperparathyroidism, unspecified	0.003	0.997	0.000
Q66.9 Congenital deformity of feet, unspecified	0.003	0.997	0.000
Q66.6 Other congenital valgus deformities of feet	0.003	0.997	0.000
Q66.5 Congenital pes planus	0.003	0.997	0.000
Q66.4 Talipes calcaneovalgus	0.003	0.997	0.000
Q66.1 Talipes calcaneovarus	0.003	0.997	0.000
Q80.9 Congenital ichthyosis, unspecified	0.003	0.997	0.000
Q80.8 Other congenital ichthyosis	0.003	0.997	0.000
Q80.4 Harlequin foetus	0.003	0.997	0.000
Q80.3 Congenital bullous ichthyosiform erythroderma	0.003	0.997	0.000
Q80.2 Lamellar ichthyosis	0.003	0.997	0.000
Q80.1 X-linked ichthyosis	0.003	0.997	0.000
Q80.0 Ichthyosis vulgaris	0.003	0.997	0.000
Q81.9 Epidermolysis bullosa, unspecified	0.003	0.997	0.000
Q81.8 Other epidermolysis bullosa	0.003	0.997	0.000
Q81.2 Epidermolysis bullosa dystrophica	0.003	0.997	0.000
Q81.1 Epidermolysis bullosa letalis	0.003	0.997	0.000
Q81.0 Epidermolysis bullosa simplex	0.003	0.997	0.000
Q84.9 Congenital malformation of integument, unspecified	0.003	0.997	0.000
Q84.8 Other specified congenital malformations of integument	0.003	0.997	0.000
Q84.6 Other congenital malformations of nails	0.003	0.997	0.000
Q84.5 Enlarged and hypertrophic nails	0.003	0.997	0.000
Q84.4 Congenital leukonychia	0.003	0.997	0.000
Q84.3 Anonychia	0.003	0.997	0.000
Q84.2 Other congenital malformations of hair	0.003	0.997	0.000
Q84.1 Congenital morphological disturbances of hair, not elsewhere classified	0.003	0.997	0.000
Q84.0 Congenital alopecia	0.003	0.997	0.000
Q86.8 Other congenital malformation syndromes due to known exogenous causes	0.003	0.997	0.000
Q86.2 Dysmorphism due to warfarin	0.003	0.997	0.000
Q86.1 Foetal hydantoin syndrome	0.003	0.997	0.000
Q86.0 Foetal alcohol syndrome (dysmorphic)	0.003	0.997	0.000
Q03 Congenital hydrocephalus	0.003	0.997	0.000
G83.4 Cauda equina syndrome	0.003	0.997	0.000
Q28.9 Congenital malformation of circulatory system, unspecified	0.003	0.997	0.000
Q28.8 Other specified congenital malformations of circulatory system	0.003	0.997	0.000
Q28.1 Other malformations of precerebral vessels	0.003	0.997	0.000
H72.1 Attic perforation of tympanic membrane	0.000	0.997	0.003
Q10.7 Congenital malformation of orbit	0.003	0.997	0.000
Q10.6 Other congenital malformations of lachrymal apparatus	0.003	0.997	0.000
Q10.5 Congenital stenosis and stricture of lachrymal duct	0.003	0.997	0.000
Q10.4 Absence and agenesis of lachrymal apparatus	0.003	0.997	0.000
Q10.3 Other congenital malformations of eyelid	0.003	0.997	0.000
Q10.2 Congenital entropion	0.003	0.997	0.000
Q10.1 Congenital ectropion	0.003	0.997	0.000
Q22.1 Congenital pulmonary valve stenosis	0.003	0.997	0.000
Q62.8 Other congenital malformations of ureter	0.003	0.997	0.000
Q62.7 Congenital vesico-uretero-renal reflux	0.003	0.997	0.000
Q62.6 Malposition of ureter	0.003	0.997	0.000
Q62.4 Agenesis of ureter	0.003	0.997	0.000
Q62.3 Other obstructive defects of renal pelvis and ureter	0.003	0.997	0.000
Q62.2 Congenital megaloureter	0.003	0.997	0.000
Q62.1 Atresia and stenosis of ureter	0.003	0.997	0.000
Q62.0 Congenital hydronephrosis	0.003	0.997	0.000
Q64.9 Congenital malformation of urinary system, unspecified	0.003	0.997	0.000
Q64.8 Other specified congenital malformations of urinary system	0.003	0.997	0.000
Q64.7 Other congenital malformations of bladder and urethra	0.003	0.997	0.000
Q64.6 Congenital diverticulum of bladder	0.003	0.997	0.000
Q64.5 Congenital absence of bladder and urethra	0.003	0.997	0.000
Q64.4 Malformation of urachus	0.003	0.997	0.000
Q64.2 Congenital posterior urethral valves	0.003	0.997	0.000
Q64.1 Exstrophy of urinary bladder	0.003	0.997	0.000
Q64.0 Epispadias	0.003	0.997	0.000
Q99.9 Chromosomal abnormality, unspecified	0.003	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations