TreeWAS – Variant ID: rs963837

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I10 Essential (primary) hypertension	0.000	0.085	0.915
I10-I15 Hypertensive diseases	0.000	0.714	0.286
E14 Unspecified diabetes mellitus	0.000	0.737	0.263
E10-E14 Diabetes mellitus	0.000	0.747	0.253
E14.9 Without complications	0.000	0.751	0.249
E11 Non-insulin-dependent diabetes mellitus	0.000	0.753	0.247
I11 Hypertensive heart disease	0.000	0.758	0.242
E14.3 With ophthalmic complications	0.000	0.761	0.239
E11.1 With ketoacidosis	0.000	0.764	0.236
E14.4 With neurological complications	0.000	0.766	0.234
E11.2 With renal complications	0.000	0.766	0.234
E10 Insulin-dependent diabetes mellitus	0.000	0.768	0.232
E14.1 With ketoacidosis	0.000	0.777	0.223
E11.5 With peripheral circulatory complications	0.000	0.779	0.221
I11.9 Hypertensive heart disease without (congestive) heart failure	0.000	0.780	0.220
E14.5 With peripheral circulatory complications	0.000	0.781	0.219
E10.8 With unspecified complications	0.000	0.790	0.210
E10.5 With peripheral circulatory complications	0.000	0.794	0.206
E11.4 With neurological complications	0.000	0.796	0.204
E14.2 Withrenal complications	0.000	0.798	0.202
I13 Hypertensive heart and renal disease	0.000	0.800	0.200
E10.3 With ophthalmic complications	0.000	0.803	0.197
E10.4 With neurological complications	0.000	0.804	0.196
E10.6 With other specified complications	0.000	0.808	0.192
E14.8 With unspecified complications	0.000	0.811	0.189
E14.7 With multiple complications	0.000	0.812	0.188
E14.0 With coma	0.000	0.812	0.188
E12 Malnutrition-related diabetes mellitus	0.000	0.819	0.181
E11.7 With multiple complications	0.000	0.823	0.177
E11.8 With unspecified complications	0.000	0.826	0.174
E13 Other specified diabetes mellitus	0.000	0.827	0.173
E11.3 With ophthalmic complications	0.000	0.829	0.171
E10.7 With multiple complications	0.000	0.830	0.170
I15 Secondary hypertension	0.000	0.833	0.166
E11.6 With other specified complications	0.000	0.836	0.164
E10.0 With coma	0.000	0.847	0.153
E14.6 With other specified complications	0.000	0.848	0.152
I11.0 Hypertensive heart disease with (congestive) heart failure	0.000	0.855	0.144
I13.9 Hypertensive heart and renal disease, unspecified	0.000	0.856	0.143
I13.1 Hypertensive heart and renal disease with renal failure	0.000	0.856	0.143
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.000	0.856	0.143
I12 Hypertensive renal disease	0.000	0.861	0.139
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.000	0.862	0.138
E12.9 Without complications	0.000	0.870	0.130
E12.8 With unspecified complications	0.000	0.870	0.130
E12.7 With multiple complications	0.000	0.870	0.130
E12.6 With other specified complications	0.000	0.870	0.130
E12.5 With peripheral circulatory complications	0.000	0.870	0.130
E12.4 With neurological complications	0.000	0.870	0.130
E12.3 With ophthalmic complications	0.000	0.870	0.130
E12.2 With renal complications	0.000	0.870	0.130
E12.1 With ketoacidosis	0.000	0.870	0.130
E12.0 With coma	0.000	0.870	0.130
E10.2 With renal complications	0.000	0.875	0.125
E13.8 With unspecified complications	0.000	0.876	0.124
E13.7 With multiple complications	0.000	0.876	0.124
E13.6 With other specified complications	0.000	0.876	0.124
E13.5 With peripheral circulatory complications	0.000	0.876	0.124
E13.4 With neurological complications	0.000	0.876	0.124
E13.3 With ophthalmic complications	0.000	0.876	0.124
E13.2 With renal complications	0.000	0.876	0.124
E13.1 With ketoacidosis	0.000	0.876	0.124
E13.0 With coma	0.000	0.876	0.124
E11.0 With coma	0.000	0.876	0.124
I15.0 Renovascular hypertension	0.000	0.880	0.120
I15.2 Hypertension secondary to endocrine disorders	0.000	0.880	0.119
I15.1 Hypertension secondary to other renal disorders	0.000	0.883	0.117
E13.9 Without complications	0.000	0.885	0.115
I15.9 Seconday hypertension, unspecified	0.000	0.891	0.109
E10.1 With ketoacidosis	0.000	0.895	0.105
I12.0 Hypertensive renal disease with renal failure	0.000	0.901	0.099
I15.8 Other secondary hypertension	0.000	0.901	0.099
E10.9 Without complications	0.000	0.942	0.058
I12.9 Hypertensive renal disease without renal failure	0.000	0.964	0.036
N92.4 Excessive bleeding in the premenopausal period	0.000	0.980	0.020
A08.1 Acute gastro-enteropathy due to Norwalk agent	0.000	0.984	0.016
H60.9 Otitis externa, unspecified	0.015	0.985	0.000
H60 Otitis externa	0.015	0.985	0.000
H60.3 Other infective otitis externa	0.015	0.985	0.000
H60.1 Cellulitis of external ear	0.014	0.986	0.000
H60.4 Cholesteatoma of external ear	0.013	0.986	0.000
A08 Viral and other specified intestinal infections	0.000	0.987	0.013
A08.4 Viral intestinal infection, unspecified	0.000	0.988	0.012
H60.2 Malignant otitis externa	0.011	0.988	0.000
H60.5 Acute otitis externa, non-infective	0.011	0.989	0.000
H60.8 Other otitis externa	0.011	0.989	0.000
H60.0 Abscess of external ear	0.011	0.989	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.990	0.010
A08.5 Other specified intestinal infections	0.000	0.990	0.010
A08.3 Other viral enteritis	0.000	0.990	0.010
M05.9 Seropositive rheumatoid arthritis, unspecified	0.000	0.991	0.009
A08.2 Adenoviral enteritis	0.000	0.991	0.009
A08.0 Rotaviral enteritis	0.000	0.991	0.009
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.992	0.008
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.992	0.008
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.000	0.992	0.008
K74.3 Primary biliary cirrhosis	0.008	0.992	0.000
M10.96 Gout, unspecified (Lower leg)	0.000	0.992	0.008
R22.3 Localised swelling, mass and lump, upper limb	0.000	0.992	0.008
G51.0 Bell's palsy	0.008	0.992	0.000
D47.3 Essential (haemorrhagic) thrombocythaemia	0.000	0.993	0.007
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.993	0.007
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.000	0.993	0.007
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.993	0.007
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.000	0.993	0.007
H60-H62 Diseases of external ear	0.007	0.993	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.000	0.994	0.006
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.000	0.994	0.006
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.994	0.006
M05 Seropositive rheumatoid arthritis	0.000	0.994	0.006
N18.4 Chronic kidney disease, stage 4	0.000	0.994	0.006
H62 Disorders of external ear in diseases classified elsewhere	0.005	0.995	0.000
M10.9 Gout, unspecified	0.000	0.995	0.005
M10.93 Gout, unspecified (Forearm)	0.000	0.995	0.005
N03.9 Unspecified	0.000	0.995	0.005
K74.5 Biliary cirrhosis, unspecified	0.005	0.995	0.000
Z91.6 Personal history of other physical trauma	0.000	0.995	0.005
H61 Other disorders of external ear	0.005	0.995	0.000
E40-E46 Malnutrition	0.000	0.995	0.005
G62.8 Other specified polyneuropathies	0.005	0.995	0.000
M10.92 Gout, unspecified (Upper arm)	0.000	0.995	0.005
H61.1 Non-infective disorders of pinna	0.005	0.995	0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.000	0.996	0.004
H62.0 Otitis externa in bacterial diseases classified elsewhere	0.004	0.996	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.000	0.996	0.004
M05.2 Rheumatoid vasculitis	0.000	0.996	0.004
M05.1 Rheumatoid lung disease	0.000	0.996	0.004
M05.0 Felty's syndrome	0.000	0.996	0.004
K74 Fibrosis and cirrhosis of liver	0.004	0.996	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.996	0.004
H62.8 Other disorders of external ear in diseases classified elsewhere	0.004	0.996	0.000
H62.4 Otitis externa in other diseases classified elsewhere	0.004	0.996	0.000
H62.3 Otitis externa in other infectious and parasitic diseases classified elsewhere	0.004	0.996	0.000
H62.2 Otitis externa in mycoses	0.004	0.996	0.000
H62.1 Otitis externa in viral diseases classified elsewhere	0.004	0.996	0.000
H61.2 Impacted cerumen	0.004	0.996	0.000
M10.90 Gout, unspecified (Multiple sites)	0.000	0.996	0.004
E06.3 Autoimmune thyroiditis	0.000	0.996	0.004
M05.8 Other seropositive rheumatoid arthritis	0.000	0.996	0.004
M10.98 Gout, unspecified (Other)	0.000	0.996	0.004
M10.95 Gout, unspecified (Pelvic region and thigh)	0.000	0.996	0.004
M10.91 Gout, unspecified (Shoulder region)	0.000	0.996	0.004
H61.0 Perichondritis of external ear	0.004	0.996	0.000
E22.0 Acromegaly and pituitary gigantism	0.000	0.996	0.004
C91.1 Chronic lymphocytic leukaemia	0.004	0.996	0.000
H61.9 Disorder of external ear, unspecified	0.004	0.996	0.000
E65-E68 Obesity and other hyperalimentation	0.000	0.996	0.004
M10.94 Gout, unspecified (Hand)	0.000	0.996	0.004
M10 Gout	0.000	0.996	0.004
E46 Unspecified protein-energy malnutrition	0.000	0.996	0.004
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.996	0.004
E45 Retarded development following protein-energy malnutrition	0.000	0.996	0.004
E43 Unspecified severe protein-energy malnutrition	0.000	0.996	0.004
E42 Marasmic kwashiorkor	0.000	0.996	0.004
E41 Nutritional marasmus	0.000	0.996	0.004
E40 Kwashiorkor	0.000	0.996	0.004
E50-E64 Other nutritional deficiencies	0.000	0.996	0.004
C43.3 Malignant melanoma of other and unspecified parts of face	0.004	0.996	0.000
E65 Localised adiposity	0.000	0.997	0.003
E20-E35 Disorders of other endocrine glands	0.000	0.997	0.003
E22 Hyperfunction of pituitary gland	0.000	0.997	0.003
M05.09 Felty's syndrome (Site unspecified)	0.000	0.997	0.003
M05.08 Felty's syndrome (Other)	0.000	0.997	0.003
M05.07 Felty's syndrome (Ankle and foot)	0.000	0.997	0.003
M05.06 Felty's syndrome (Lower leg)	0.000	0.997	0.003
M05.05 Felty's syndrome (Pelvic region and thigh)	0.000	0.997	0.003
M05.04 Felty's syndrome (Hand)	0.000	0.997	0.003
M05.03 Felty's syndrome (Forearm)	0.000	0.997	0.003
M05.02 Felty's syndrome (Upper arm)	0.000	0.997	0.003
M05.01 Felty's syndrome (Shoulder region)	0.000	0.997	0.003
M05.00 Felty's syndrome (Multiple sites)	0.000	0.997	0.003
M05.19 Rheumatoid lung disease (Site unspecified)	0.000	0.997	0.003
M05.18 Rheumatoid lung disease (Other)	0.000	0.997	0.003
M05.17 Rheumatoid lung disease (Ankle and foot)	0.000	0.997	0.003
M05.16 Rheumatoid lung disease (Lower leg)	0.000	0.997	0.003
M05.15 Rheumatoid lung disease (Pelvic region and thigh)	0.000	0.997	0.003
M05.14 Rheumatoid lung disease (Hand)	0.000	0.997	0.003
M05.13 Rheumatoid lung disease (Forearm)	0.000	0.997	0.003
M05.12 Rheumatoid lung disease (Upper arm)	0.000	0.997	0.003
M05.11 Rheumatoid lung disease (Shoulder region)	0.000	0.997	0.003
M05.10 Rheumatoid lung disease (Multiple sites)	0.000	0.997	0.003
M05.29 Rheumatoid vasculitis (Site unspecified)	0.000	0.997	0.003
M05.28 Rheumatoid vasculitis (Other)	0.000	0.997	0.003
M05.27 Rheumatoid vasculitis (Ankle and foot)	0.000	0.997	0.003
M05.26 Rheumatoid vasculitis (Lower leg)	0.000	0.997	0.003
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)	0.000	0.997	0.003
M05.24 Rheumatoid vasculitis (Hand)	0.000	0.997	0.003
M05.23 Rheumatoid vasculitis (Forearm)	0.000	0.997	0.003
M05.22 Rheumatoid vasculitis (Upper arm)	0.000	0.997	0.003
M05.21 Rheumatoid vasculitis (Shoulder region)	0.000	0.997	0.003
M05.20 Rheumatoid vasculitis (Multiple sites)	0.000	0.997	0.003
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)	0.000	0.997	0.003
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)	0.000	0.997	0.003
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)	0.000	0.997	0.003
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)	0.000	0.997	0.003
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)	0.000	0.997	0.003
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)	0.000	0.997	0.003
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)	0.000	0.997	0.003
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)	0.000	0.997	0.003
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)	0.000	0.997	0.003
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)	0.000	0.997	0.003
E20.9 Hypoparathyroidism, unspecified	0.000	0.997	0.003
K74.4 Secondary biliary cirrhosis	0.003	0.997	0.000
K74.2 Hepatic fibrosis with hepatic sclerosis	0.003	0.997	0.000
E20 Hypoparathyroidism	0.000	0.997	0.003
E15 Nondiabetic hypoglycaemic coma	0.000	0.997	0.003
K74.1 Hepatic sclerosis	0.003	0.997	0.000
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)	0.000	0.997	0.003
M05.88 Other seropositive rheumatoid arthritis (Other)	0.000	0.997	0.003
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)	0.000	0.997	0.003
M05.86 Other seropositive rheumatoid arthritis (Lower leg)	0.000	0.997	0.003
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)	0.000	0.997	0.003
M05.84 Other seropositive rheumatoid arthritis (Hand)	0.000	0.997	0.003
M05.83 Other seropositive rheumatoid arthritis (Forearm)	0.000	0.997	0.003
M05.82 Other seropositive rheumatoid arthritis (Upper arm)	0.000	0.997	0.003
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)	0.000	0.997	0.003
E23.0 Hypopituitarism	0.000	0.997	0.003
N18.9 Chronic renal failure, unspecified	0.000	0.997	0.003
H04.2 Epiphora	0.003	0.997	0.000
E06 Thyroiditis	0.000	0.997	0.003
M05-M14 Inflammatory polyarthropathies	0.000	0.997	0.003
E67 Other hyperalimentation	0.000	0.997	0.003
E68 Sequelae of hyperalimentation	0.000	0.997	0.003
H61.3 Acquired stenosis of external ear canal	0.003	0.997	0.000
E53 Deficiency of other B group vitamins	0.000	0.997	0.003
M10.4 Other secondary gout	0.000	0.997	0.003
M10.3 Gout due to impairment of renal function	0.000	0.997	0.003
M10.2 Drug-induced gout	0.000	0.997	0.003
M10.1 Lead-induced gout	0.000	0.997	0.003
E23 Hypofunction and other disorders of pituitary gland	0.000	0.997	0.003
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)	0.000	0.997	0.003
E44.1 Mild protein-energy malnutrition	0.000	0.997	0.003
E44.0 Moderate protein-energy malnutrition	0.000	0.997	0.003
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.997	0.003
E63 Other nutritional deficiencies	0.000	0.997	0.003
E50 Vitamin A deficiency	0.000	0.997	0.003
E60 Dietary zinc deficiency	0.000	0.997	0.003
E59 Dietary selenium deficiency	0.000	0.997	0.003
E54 Ascorbic acid deficiency	0.000	0.997	0.003
E52 Niacin deficiency [pellagra]	0.000	0.997	0.003
M12 Other specific arthropathies	0.000	0.997	0.003
M07.39 Other psoriatic arthropathies (Site unspecified)	0.000	0.997	0.003
H72.0 Central perforation of tympanic membrane	0.000	0.997	0.003
E61 Deficiency of other nutrient elements	0.000	0.997	0.003
E61.2 Magnesium deficiency	0.000	0.997	0.003
E51 Thiamine deficiency	0.000	0.997	0.003
Z04.8 Examination and observation for other specified reasons	0.000	0.997	0.003
E07 Other disorders of thyroid	0.000	0.997	0.003
E56 Other vitamin deficiencies	0.000	0.997	0.003
E58 Dietary calcium deficiency	0.000	0.997	0.003
E07.8 Other specified disorders of thyroid	0.000	0.997	0.003
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.997	0.003
E22.8 Other hyperfunction of pituitary gland	0.000	0.997	0.003
E16 Other disorders of pancreatic internal secretion	0.000	0.997	0.003
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.997	0.003
E32 Diseases of thymus	0.000	0.997	0.003
E30 Disorders of puberty, not elsewhere classified	0.000	0.997	0.003
N18 Chronic renal failure	0.000	0.997	0.003
E22.1 Hyperprolactinaemia	0.000	0.997	0.003
E20.8 Other hypoparathyroidism	0.000	0.997	0.002
E20.1 Pseudohypoparathyroidism	0.000	0.997	0.002
E20.0 Idiopathic hypoparathyroidism	0.000	0.997	0.002
E53.8 Deficiency of other specified B group vitamins	0.000	0.997	0.003
E28.3 Primary ovarian failure	0.000	0.997	0.003
H73.8 Other specified disorders of tympanic membrane	0.003	0.997	0.000
M12.3 Palindromic rheumatism	0.000	0.997	0.002
E00-E07 Disorders of thyroid gland	0.000	0.997	0.003
E28 Ovarian dysfunction	0.000	0.997	0.003
M10.99 Gout, unspecified (Site unspecified)	0.000	0.997	0.003
M10.0 Idiopathic gout	0.000	0.997	0.002
E31 Polyglandular dysfunction	0.000	0.997	0.002
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.000	0.997	0.003
E07.9 Disorder of thyroid, unspecified	0.000	0.997	0.003
E24 Cushing's syndrome	0.000	0.997	0.002
E06.1 Subacute thyroiditis	0.000	0.997	0.002
N90.7 Vulvar cyst	0.000	0.997	0.003
M12.39 Palindromic rheumatism (Site unspecified)	0.000	0.997	0.002
E26 Hyperaldosteronism	0.000	0.997	0.002
E25 Adrenogenital disorders	0.000	0.997	0.002
M11.86 Other specified crystal arthropathies (Lower leg)	0.000	0.997	0.002
M07 Psoriatic and enteropathic arthropathies	0.000	0.997	0.002
E06.4 Drug-induced thyroiditis	0.000	0.997	0.002
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.997	0.002
E06.0 Acute thyroiditis	0.000	0.997	0.002
E34 Other endocrine disorders	0.000	0.997	0.002
M09 Juvenile arthritis in diseases classified elsewhere	0.000	0.997	0.002
E67.8 Other specified hyperalimentation	0.000	0.998	0.002
E67.3 Hypervitaminosis D	0.000	0.998	0.002
E67.2 Megavitamin-B6 syndrome	0.000	0.998	0.002
E67.1 Hypercarotenaemia	0.000	0.998	0.002
E67.0 Hypervitaminosis A	0.000	0.998	0.002
G55.3 Nerve root and plexus compressions in other dorsopathies	0.000	0.998	0.002
K75.0 Abscess of liver	0.000	0.998	0.002
M11 Other crystal arthropathies	0.000	0.998	0.002
E53.1 Pyridoxine deficiency	0.000	0.998	0.002
E53.0 Riboflavin deficiency	0.000	0.998	0.002
M12.2 Villonodular synovitis (pigmented)	0.000	0.998	0.002
M10.19 Lead-induced gout (Site unspecified)	0.000	0.998	0.002
M10.18 Lead-induced gout (Other)	0.000	0.998	0.002
M10.17 Lead-induced gout (Ankle and foot)	0.000	0.998	0.002
M10.16 Lead-induced gout (Lower leg)	0.000	0.998	0.002
M10.15 Lead-induced gout (Pelvic region and thigh)	0.000	0.998	0.002
M10.14 Lead-induced gout (Hand)	0.000	0.998	0.002
M10.13 Lead-induced gout (Forearm)	0.000	0.998	0.002
M10.12 Lead-induced gout (Upper arm)	0.000	0.998	0.002
M10.11 Lead-induced gout (Shoulder region)	0.000	0.998	0.002
M10.10 Lead-induced gout (Multiple sites)	0.000	0.998	0.002
M10.29 Drug-induced gout (Site unspecified)	0.000	0.998	0.002
M10.28 Drug-induced gout (Other)	0.000	0.998	0.002
M10.27 Drug-induced gout (Ankle and foot)	0.000	0.998	0.002
M10.26 Drug-induced gout (Lower leg)	0.000	0.998	0.002
M10.25 Drug-induced gout (Pelvic region and thigh)	0.000	0.998	0.002
M10.24 Drug-induced gout (Hand)	0.000	0.998	0.002
M10.23 Drug-induced gout (Forearm)	0.000	0.998	0.002
M10.22 Drug-induced gout (Upper arm)	0.000	0.998	0.002
M10.21 Drug-induced gout (Shoulder region)	0.000	0.998	0.002
M10.20 Drug-induced gout (Multiple sites)	0.000	0.998	0.002
M10.39 Gout due to impairment of renal function (Site unspecified)	0.000	0.998	0.002
M10.38 Gout due to impairment of renal function (Other)	0.000	0.998	0.002
M10.37 Gout due to impairment of renal function (Ankle and foot)	0.000	0.998	0.002
M10.36 Gout due to impairment of renal function (Lower leg)	0.000	0.998	0.002
M10.35 Gout due to impairment of renal function (Pelvic region and thigh)	0.000	0.998	0.002
M10.34 Gout due to impairment of renal function (Hand)	0.000	0.998	0.002
M10.33 Gout due to impairment of renal function (Forearm)	0.000	0.998	0.002
M10.32 Gout due to impairment of renal function (Upper arm)	0.000	0.998	0.002
M10.31 Gout due to impairment of renal function (Shoulder region)	0.000	0.998	0.002
M10.30 Gout due to impairment of renal function (Multiple sites)	0.000	0.998	0.002
M10.49 Other secondary gout (Site unspecified)	0.000	0.998	0.002
M10.48 Other secondary gout (Other)	0.000	0.998	0.002
M10.47 Other secondary gout (Ankle and foot)	0.000	0.998	0.002
M10.46 Other secondary gout (Lower leg)	0.000	0.998	0.002
M10.45 Other secondary gout (Pelvic region and thigh)	0.000	0.998	0.002
M10.44 Other secondary gout (Hand)	0.000	0.998	0.002
M10.43 Other secondary gout (Forearm)	0.000	0.998	0.002
M10.42 Other secondary gout (Upper arm)	0.000	0.998	0.002
M10.41 Other secondary gout (Shoulder region)	0.000	0.998	0.002
M10.40 Other secondary gout (Multiple sites)	0.000	0.998	0.002
M11.8 Other specified crystal arthropathies	0.000	0.998	0.002
M12.8 Other specific arthropathies, not elsewhere classified	0.000	0.998	0.002
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.998	0.002
E23.1 Drug-induced hypopituitarism	0.000	0.998	0.002
E29 Testicular dysfunction	0.000	0.998	0.002
J98.8 Other specified respiratory disorders	0.002	0.998	0.000
E24.2 Drug-induced Cushing's syndrome	0.000	0.998	0.002
K74.0 Hepatic fibrosis	0.002	0.998	0.000
E34.9 Endocrine disorder, unspecified	0.000	0.998	0.002
E50.9 Vitamin A deficiency, unspecified	0.000	0.998	0.002
E50.8 Other manifestations of vitamin A deficiency	0.000	0.998	0.002
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.998	0.002
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.998	0.002
E50.5 Vitamin A deficiency with night blindness	0.000	0.998	0.002
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.998	0.002
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.998	0.002
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.998	0.002
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.998	0.002
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.998	0.002
E63.9 Nutritional deficiency, unspecified	0.000	0.998	0.002
E63.8 Other specified nutritional deficiencies	0.000	0.998	0.002
E63.1 Imbalance of constituents of food intake	0.000	0.998	0.002
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.998	0.002
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.998	0.002
E64.8 Sequelae of other nutritional deficiencies	0.000	0.998	0.002
E64.3 Sequelae of rickets	0.000	0.998	0.002
E64.2 Sequelae of vitamin C deficiency	0.000	0.998	0.002
E64.1 Sequelae of vitamin A deficiency	0.000	0.998	0.002
E64.0 Sequelae of protein-energy malnutrition	0.000	0.998	0.002
M12.4 Intermittent hydrarthrosis	0.000	0.998	0.002
M12.1 Kaschin-Beck disease	0.000	0.998	0.002
M12.0 Chronic postrheumatic arthropathy [Jaccoud]	0.000	0.998	0.002
M12.24 Villonodular synovitis (pigmented) (Hand)	0.000	0.998	0.002
E06.5 Other chronic thyroiditis	0.000	0.998	0.002
M12.5 Traumatic arthropathy	0.000	0.998	0.002
M10.07 Idiopathic gout (Ankle and foot)	0.000	0.998	0.002
E53.9 Vitamin B deficiency, unspecified	0.000	0.998	0.002
E61.9 Deficiency of nutrient element, unspecified	0.000	0.998	0.002
E61.8 Deficiency of other specified nutrient elements	0.000	0.998	0.002
E61.7 Deficiency of multiple nutrient elements	0.000	0.998	0.002
E61.6 Vanadium deficiency	0.000	0.998	0.002
E61.5 Molybdenum deficiency	0.000	0.998	0.002
E61.4 Chromium deficiency	0.000	0.998	0.002
E61.3 Manganese deficiency	0.000	0.998	0.002
E61.0 Copper deficiency	0.000	0.998	0.002
E07.1 Dyshormogenetic goitre	0.000	0.998	0.002
E07.0 Hypersecretion of calcitonin	0.000	0.998	0.002
E51.9 Thiamine deficiency, unspecified	0.000	0.998	0.002
E51.8 Other manifestations of thiamine deficiency	0.000	0.998	0.002
E51.1 Beriberi	0.000	0.998	0.002
G51 Facial nerve disorders	0.002	0.998	0.000
M08 Juvenile arthritis	0.000	0.998	0.002
E56.9 Vitamin deficiency, unspecified	0.000	0.998	0.002
E56.8 Deficiency of other vitamins	0.000	0.998	0.002
E56.0 Deficiency of vitamin E	0.000	0.998	0.002
E06.9 Thyroiditis, unspecified	0.000	0.998	0.002
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.998	0.002
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.998	0.002
E16.4 Abnormal secretion of gastrin	0.000	0.998	0.002
E16.3 Increased secretion of glucagon	0.000	0.998	0.002
E30.9 Disorder of puberty, unspecified	0.000	0.998	0.002
E30.8 Other disorders of puberty	0.000	0.998	0.002
E30.1 Precocious puberty	0.000	0.998	0.002
E30.0 Delayed puberty	0.000	0.998	0.002
E32.9 Disease of thymus, unspecified	0.000	0.998	0.002
E32.8 Other diseases of thymus	0.000	0.998	0.002
E32.1 Abscess of thymus	0.000	0.998	0.002
E32.0 Persistent hyperplasia of thymus	0.000	0.998	0.002
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.998	0.002
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.998	0.002
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.998	0.002
X41.9 Unspecified place	0.002	0.998	0.000
N18.1 Chronic kidney disease, stage 1	0.000	0.998	0.002
K11.5 Sialolithiasis	0.000	0.998	0.002
M06.4 Inflammatory polyarthropathy	0.000	0.998	0.002
S00.0 Superficial injury of scalp	0.000	0.998	0.002
M07.3 Other psoriatic arthropathies	0.000	0.998	0.002
W55.0 Home	0.000	0.998	0.002
Z21 Asymptomatic human immunodeficiency virus [HIV] infection status	0.000	0.998	0.002
E23.7 Disorder of pituitary gland, unspecified	0.000	0.998	0.002
E51.2 Wernicke's encephalopathy	0.000	0.998	0.002
E55 Vitamin D deficiency	0.000	0.998	0.002
K74.6 Other and unspecified cirrhosis of liver	0.002	0.998	0.000
M12.38 Palindromic rheumatism (Other)	0.000	0.998	0.002
M12.37 Palindromic rheumatism (Ankle and foot)	0.000	0.998	0.002
M12.36 Palindromic rheumatism (Lower leg)	0.000	0.998	0.002
M12.35 Palindromic rheumatism (Pelvic region and thigh)	0.000	0.998	0.002
M12.34 Palindromic rheumatism (Hand)	0.000	0.998	0.002
M12.33 Palindromic rheumatism (Forearm)	0.000	0.998	0.002
M12.32 Palindromic rheumatism (Upper arm)	0.000	0.998	0.002
M12.31 Palindromic rheumatism (Shoulder region)	0.000	0.998	0.002
E23.6 Other disorders of pituitary gland	0.000	0.998	0.002
E23.2 Diabetes insipidus	0.000	0.998	0.002
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.998	0.002
E00 Congenital iodine-deficiency syndrome	0.000	0.998	0.002
M10.08 Idiopathic gout (Other)	0.000	0.998	0.002
M10.05 Idiopathic gout (Pelvic region and thigh)	0.000	0.998	0.002
M10.03 Idiopathic gout (Forearm)	0.000	0.998	0.002
M10.02 Idiopathic gout (Upper arm)	0.000	0.998	0.002
M10.01 Idiopathic gout (Shoulder region)	0.000	0.998	0.002
E28.9 Ovarian dysfunction, unspecified	0.000	0.998	0.002
E28.8 Other ovarian dysfunction	0.000	0.998	0.002
E28.1 Androgen excess	0.000	0.998	0.002
E28.0 Oestrogen excess	0.000	0.998	0.002
E31.9 Polyglandular dysfunction, unspecified	0.000	0.998	0.002
E31.8 Other polyglandular dysfunction	0.000	0.998	0.002
E31.1 Polyglandular hyperfunction	0.000	0.998	0.002
M12.88 Other specific arthropathies, not elsewhere classified (Other)	0.000	0.998	0.002
E24.8 Other Cushing's syndrome	0.000	0.998	0.002
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.998	0.002
E24.3 Ectopic ACTH syndrome	0.000	0.998	0.002
E24.1 Nelson's syndrome	0.000	0.998	0.002
E56.1 Deficiency of vitamin K	0.000	0.998	0.002
M10.00 Idiopathic gout (Multiple sites)	0.000	0.998	0.002
E25.9 Adrenogenital disorder, unspecified	0.000	0.998	0.002
E25.8 Other adrenogenital disorders	0.000	0.998	0.002
E26.8 Other hyperaldosteronism	0.000	0.998	0.002
E26.1 Secondary hyperaldosteronism	0.000	0.998	0.002
N18.0 End-stage renal disease	0.000	0.998	0.002
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.998	0.002
G51.3 Clonic hemifacial spasm	0.002	0.998	0.000
M07.5 Arthropathy in ulcerative colitis	0.000	0.998	0.002
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.000	0.998	0.002
M07.2 Psoriatic spondylitis	0.000	0.998	0.002
M07.1 Arthritis mutilans	0.000	0.998	0.002
M07.0 Distal interphalangeal psoriatic arthropathy	0.000	0.998	0.002
S00.9 Superficial injury of head, part unspecified	0.000	0.998	0.002
X49.9 Unspecified place	0.002	0.998	0.000
Z84.8 Family history of other specified conditions	0.000	0.998	0.002
D69.3 Idiopathic thrombocytopenic purpura	0.000	0.998	0.002
E34.5 Androgen resistance syndrome	0.000	0.998	0.002
E34.4 Constitutional tall stature	0.000	0.998	0.002
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.998	0.002
E34.1 Other hypersecretion of intestinal hormones	0.000	0.998	0.002
H61.8 Other specified disorders of external ear	0.002	0.998	0.000
M09.8 Juvenile arthritis in other diseases classified elsewhere	0.000	0.998	0.002
M09.2 Juvenile arthritis in ulcerative colitis	0.000	0.998	0.002
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]	0.000	0.998	0.002
M09.0 Juvenile arthritis in psoriasis	0.000	0.998	0.002
M12.29 Villonodular synovitis (pigmented) (Site unspecified)	0.000	0.998	0.002
M12.28 Villonodular synovitis (pigmented) (Other)	0.000	0.998	0.002
M12.27 Villonodular synovitis (pigmented) (Ankle and foot)	0.000	0.998	0.002
M12.25 Villonodular synovitis (pigmented) (Pelvic region and thigh)	0.000	0.998	0.002
M12.23 Villonodular synovitis (pigmented) (Forearm)	0.000	0.998	0.002
M12.22 Villonodular synovitis (pigmented) (Upper arm)	0.000	0.998	0.002
M12.21 Villonodular synovitis (pigmented) (Shoulder region)	0.000	0.998	0.002
M12.20 Villonodular synovitis (pigmented) (Multiple sites)	0.000	0.998	0.002
M11.1 Familial chondrocalcinosis	0.000	0.998	0.002
M11.0 Hydroxyapatite deposition disease	0.000	0.998	0.002
M11.89 Other specified crystal arthropathies (Site unspecified)	0.000	0.998	0.002
M11.88 Other specified crystal arthropathies (Other)	0.000	0.998	0.002
M11.87 Other specified crystal arthropathies (Ankle and foot)	0.000	0.998	0.002
M11.85 Other specified crystal arthropathies (Pelvic region and thigh)	0.000	0.998	0.002
M11.84 Other specified crystal arthropathies (Hand)	0.000	0.998	0.002
M11.83 Other specified crystal arthropathies (Forearm)	0.000	0.998	0.002
M11.82 Other specified crystal arthropathies (Upper arm)	0.000	0.998	0.002
M11.81 Other specified crystal arthropathies (Shoulder region)	0.000	0.998	0.002
M11.80 Other specified crystal arthropathies (Multiple sites)	0.000	0.998	0.002
M12.89 Other specific arthropathies, not elsewhere classified (Site unspecified)	0.000	0.998	0.002
M12.87 Other specific arthropathies, not elsewhere classified (Ankle and foot)	0.000	0.998	0.002
M12.86 Other specific arthropathies, not elsewhere classified (Lower leg)	0.000	0.998	0.002
M12.85 Other specific arthropathies, not elsewhere classified (Pelvic region and thigh)	0.000	0.998	0.002
M12.84 Other specific arthropathies, not elsewhere classified (Hand)	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations