TreeWAS – Variant ID: rs9659323

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E05 Thyrotoxicosis [hyperthyroidism]	0.217	0.783	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.214	0.786	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.205	0.795	0.000
E04.2 Non-toxic multinodular goitre	0.201	0.799	0.000
E00-E07 Disorders of thyroid gland	0.200	0.800	0.000
E04 Other non-toxic goitre	0.198	0.802	0.000
E03 Other hypothyroidism	0.180	0.820	0.000
E05.8 Other thyrotoxicosis	0.174	0.826	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.171	0.829	0.000
E05.9 Thyrotoxicosis, unspecified	0.170	0.830	0.000
E03.9 Hypothyroidism, unspecified	0.161	0.839	0.000
E04.0 Non-toxic diffuse goitre	0.160	0.840	0.000
E05.5 Thyroid crisis or storm	0.156	0.844	0.000
E05.4 Thyrotoxicosis factitia	0.156	0.844	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.156	0.844	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.151	0.849	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.147	0.853	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.144	0.856	0.000
E00 Congenital iodine-deficiency syndrome	0.144	0.856	0.000
E04.8 Other specified non-toxic goitre	0.142	0.858	0.000
E04.1 Non-toxic single thyroid nodule	0.134	0.866	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.133	0.867	0.000
E03.5 Myxoedema coma	0.129	0.871	0.000
E03.4 Atrophy of thyroid (acquired)	0.129	0.871	0.000
E03.3 Postinfectious hypothyroidism	0.129	0.871	0.000
E03.8 Other specified hypothyroidism	0.128	0.872	0.000
E06 Thyroiditis	0.116	0.884	0.000
E07 Other disorders of thyroid	0.110	0.889	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.103	0.897	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.103	0.897	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.103	0.897	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.103	0.897	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.103	0.897	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.103	0.897	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.103	0.897	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.103	0.897	0.000
E03.1 Congenital hypothyroidism without goitre	0.102	0.898	0.000
E07.8 Other specified disorders of thyroid	0.088	0.911	0.000
E06.9 Thyroiditis, unspecified	0.085	0.915	0.000
E06.4 Drug-induced thyroiditis	0.084	0.916	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.084	0.916	0.000
E06.0 Acute thyroiditis	0.084	0.916	0.000
E06.5 Other chronic thyroiditis	0.083	0.917	0.000
E07.1 Dyshormogenetic goitre	0.079	0.920	0.000
E07.0 Hypersecretion of calcitonin	0.079	0.920	0.000
E06.1 Subacute thyroiditis	0.076	0.924	0.000
E04.9 Non-toxic goitre, unspecified	0.070	0.930	0.000
E06.3 Autoimmune thyroiditis	0.066	0.934	0.000
Z95.5 Presence of coronary angioplasty implant and graft	0.050	0.950	0.000
Z95.8 Presence of other cardiac and vascular implants and grafts	0.041	0.959	0.000
Z95 Presence of cardiac and vascular implants and grafts	0.038	0.962	0.000
Z95.0 Presence of cardiac pacemaker	0.037	0.963	0.000
M25.51 Pain in joint (Shoulder region)	0.028	0.972	0.000
Z95.2 Presence of prosthetic heart valve	0.027	0.973	0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.025	0.975	0.000
Z95.3 Presence of xenogenic heart valve	0.024	0.976	0.000
J18.9 Pneumonia, unspecified	0.022	0.978	0.000
L29.9 Pruritus, unspecified	0.000	0.979	0.021
E07.9 Disorder of thyroid, unspecified	0.020	0.980	0.000
L29.2 Pruritus vulvae	0.000	0.980	0.020
H61.0 Perichondritis of external ear	0.020	0.980	0.000
E10.9 Without complications	0.020	0.980	0.000
L29 Pruritus	0.000	0.980	0.020
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.017	0.983	0.000
L29.8 Other pruritus	0.000	0.985	0.015
L29.1 Pruritus scroti	0.000	0.986	0.014
L29.0 Pruritus ani	0.000	0.986	0.014
H61 Other disorders of external ear	0.014	0.986	0.000
T78.4 Allergy, unspecified	0.014	0.986	0.000
L29.3 Anogenital pruritus, unspecified	0.000	0.987	0.013
H60 Otitis externa	0.013	0.987	0.000
H60.1 Cellulitis of external ear	0.013	0.987	0.000
T78.0 Anaphylactic shock due to adverse food reaction	0.012	0.988	0.000
H60.9 Otitis externa, unspecified	0.012	0.988	0.000
H61.9 Disorder of external ear, unspecified	0.012	0.988	0.000
H60-H62 Diseases of external ear	0.012	0.988	0.000
H60.4 Cholesteatoma of external ear	0.011	0.988	0.000
T78 Adverse effects, not elsewhere classified	0.012	0.988	0.000
H61.1 Non-infective disorders of pinna	0.010	0.990	0.000
H60.8 Other otitis externa	0.010	0.990	0.000
L20-L30 Dermatitis and eczema	0.000	0.991	0.009
T78.2 Anaphylactic shock, unspecified	0.009	0.991	0.000
I69 Sequelae of cerebrovascular disease	0.009	0.991	0.000
H60.0 Abscess of external ear	0.009	0.991	0.000
L27.0 Generalised skin eruption due to drugs and medicaments	0.000	0.991	0.009
H60.5 Acute otitis externa, non-infective	0.009	0.991	0.000
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung	0.009	0.991	0.000
H60.3 Other infective otitis externa	0.009	0.991	0.000
L27 Dermatitis due to substances taken internally	0.000	0.991	0.009
T78.8 Other adverse effects, not elsewhere classified	0.008	0.992	0.000
H61.3 Acquired stenosis of external ear canal	0.008	0.992	0.000
T78.1 Other adverse food reactions, not elsewhere classified	0.008	0.992	0.000
H62 Disorders of external ear in diseases classified elsewhere	0.008	0.992	0.000
R07.0 Pain in throat	0.008	0.992	0.000
L23 Allergic contact dermatitis	0.000	0.992	0.008
L21 Seborrhoeic dermatitis	0.000	0.992	0.008
H60.2 Malignant otitis externa	0.008	0.992	0.000
K13.7 Other and unspecified lesions of oral mucosa	0.008	0.992	0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.008	0.992	0.000
T78.9 Adverse effect, unspecified	0.008	0.992	0.000
J18 Pneumonia, organism unspecified	0.007	0.993	0.000
I61 Intracerebral haemorrhage	0.007	0.993	0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.007	0.993	0.000
L23.5 Allergic contact dermatitis due to other chemical products	0.000	0.993	0.007
C71.2 Temporal lobe	0.007	0.993	0.000
I61.9 Intracerebral haemorrhage, unspecified	0.007	0.993	0.000
H61.8 Other specified disorders of external ear	0.007	0.993	0.000
J30.1 Allergic rhinitis due to pollen	0.007	0.993	0.000
L21.9 Seborrhoeic dermatitis, unspecified	0.000	0.993	0.007
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.007	0.993	0.000
T78.3 Angioneurotic oedema	0.007	0.993	0.000
L24 Irritant contact dermatitis	0.000	0.993	0.007
L22 Diaper [napkin] dermatitis	0.000	0.993	0.007
L25 Unspecified contact dermatitis	0.000	0.993	0.007
R20.2 Paraesthesia of skin	0.007	0.993	0.000
I61.5 Intracerebral haemorrhage, intraventricular	0.007	0.993	0.000
I69.1 Sequelae of intracerebral haemorrhage	0.007	0.993	0.000
J18.0 Bronchopneumonia, unspecified	0.007	0.993	0.000
L27.2 Dermatitis due to ingested food	0.000	0.993	0.006
L27.9 Dermatitis due to unspecified substance taken internally	0.000	0.993	0.006
L27.8 Dermatitis due to other substances taken internally	0.000	0.993	0.006
H61.2 Impacted cerumen	0.006	0.994	0.000
H62.8 Other disorders of external ear in diseases classified elsewhere	0.006	0.994	0.000
H62.4 Otitis externa in other diseases classified elsewhere	0.006	0.994	0.000
H62.3 Otitis externa in other infectious and parasitic diseases classified elsewhere	0.006	0.994	0.000
H62.2 Otitis externa in mycoses	0.006	0.994	0.000
H62.1 Otitis externa in viral diseases classified elsewhere	0.006	0.994	0.000
L23.8 Allergic contact dermatitis due to other agents	0.000	0.994	0.006
L23.1 Allergic contact dermatitis due to adhesives	0.000	0.994	0.006
L21.8 Other seborrhoeic dermatitis	0.000	0.994	0.006
L21.1 Seborrhoeic infantile dermatitis	0.000	0.994	0.006
L21.0 Seborrhoea capitis	0.000	0.994	0.006
L23.7 Allergic contact dermatitis due to plants, except food	0.000	0.994	0.006
L23.6 Allergic contact dermatitis due to food in contact with the skin	0.000	0.994	0.006
L23.4 Allergic contact dermatitis due to dyes	0.000	0.994	0.006
L23.3 Allergic contact dermatitis due to drugs in contact with the skin	0.000	0.994	0.006
L23.2 Allergic contact dermatitis due to cosmetics	0.000	0.994	0.006
L23.0 Allergic contact dermatitis due to metals	0.000	0.994	0.006
L20 Atopic dermatitis	0.000	0.994	0.006
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.006	0.994	0.000
L28 Lichen simplex chronicus and prurigo	0.000	0.994	0.006
E11.2 With renal complications	0.000	0.994	0.006
L26 Exfoliative dermatitis	0.000	0.994	0.006
M70.22 Olecranon bursitis-Upper arm	0.006	0.994	0.000
H62.0 Otitis externa in bacterial diseases classified elsewhere	0.005	0.994	0.000
J18.8 Other pneumonia, organism unspecified	0.006	0.994	0.000
J18.2 Hypostatic pneumonia, unspecified	0.005	0.994	0.000
I61.3 Intracerebral haemorrhage in brain stem	0.005	0.994	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.006	0.994	0.000
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs	0.005	0.995	0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.005	0.995	0.000
C71 Malignant neoplasm of brain	0.005	0.995	0.000
E89.0 Postprocedural hypothyroidism	0.005	0.995	0.000
I61.4 Intracerebral haemorrhage in cerebellum	0.005	0.995	0.000
E78.2 Mixed hyperlipidaemia	0.005	0.995	0.000
L27.1 Localised skin eruption due to drugs and medicaments	0.000	0.995	0.005
L23.9 Allergic contact dermatitis, unspecified cause	0.000	0.995	0.005
L24.9 Irritant contact dermatitis, unspecified cause	0.000	0.995	0.005
L24.8 Irritant contact dermatitis due to other agents	0.000	0.995	0.005
L24.7 Irritant contact dermatitis due to plants, except food	0.000	0.995	0.005
L24.6 Irritant contact dermatitis due to food in contact with the skin	0.000	0.995	0.005
L24.5 Irritant contact dermatitis due to other chemical products	0.000	0.995	0.005
L24.4 Irritant contact dermatitis due to drugs in contact with the skin	0.000	0.995	0.005
L24.3 Irritant contact dermatitis due to cosmetics	0.000	0.995	0.005
L24.2 Irritant contact dermatitis due to solvents	0.000	0.995	0.005
L24.1 Irritant contact dermatitis due to oils and greases	0.000	0.995	0.005
L24.0 Irritant contact dermatitis due to detergents	0.000	0.995	0.005
L25.8 Unspecified contact dermatitis due to other agents	0.000	0.995	0.005
L25.5 Unspecified contact dermatitis due to plants, except food	0.000	0.995	0.005
L25.4 Unspecified contact dermatitis due to food in contact with the skin	0.000	0.995	0.005
L25.3 Unspecified contact dermatitis due to other chemical products	0.000	0.995	0.005
L25.2 Unspecified contact dermatitis due to dyes	0.000	0.995	0.005
L25.1 Unspecified contact dermatitis due to drugs in contact with the skin	0.000	0.995	0.005
L25.0 Unspecified contact dermatitis due to cosmetics	0.000	0.995	0.005
L25.9 Unspecified contact dermatitis, unspecified cause	0.000	0.995	0.005
I69.3 Sequelae of cerebral infarction	0.005	0.995	0.000
C71.0 Cerebrum, except lobes and ventricles	0.005	0.995	0.000
I61.6 Intracerebral haemorrhage, multiple localised	0.005	0.995	0.000
K02.8 Other dental caries	0.005	0.995	0.000
R07.4 Chest pain, unspecified	0.005	0.995	0.000
S61.8 Open wound of other parts of wrist and hand	0.000	0.995	0.005
I67.8 Other specified cerebrovascular diseases	0.005	0.995	0.000
I61.8 Other intracerebral haemorrhage	0.005	0.995	0.000
L30 Other dermatitis	0.000	0.995	0.005
L20.8 Other atopic dermatitis	0.000	0.995	0.004
L20.0 Besnier's prurigo	0.000	0.995	0.004
C71.5 Cerebral ventricle	0.004	0.995	0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)	0.005	0.995	0.000
C71.4 Occipital lobe	0.004	0.996	0.000
C71.3 Parietal lobe	0.004	0.996	0.000
L28.1 Prurigo nodularis	0.000	0.996	0.004
I60-I69 Cerebrovascular diseases	0.004	0.996	0.000
C71.8 Overlapping lesion of brain	0.004	0.996	0.000
C71.7 Brain stem	0.004	0.996	0.000
R07 Pain in throat and chest	0.004	0.996	0.000
I68.0 Cerebral amyloid angiopathy	0.004	0.996	0.000
Z87.8 Personal history of other specified conditions	0.000	0.996	0.004
I68 Cerebrovascular disorders in diseases classified elsewhere	0.004	0.996	0.000
R07.1 Chest pain on breathing	0.004	0.996	0.000
C71.6 Cerebellum	0.004	0.996	0.000
M95.0 Acquired deformity of nose	0.000	0.996	0.004
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome	0.000	0.996	0.004
L28.2 Other prurigo	0.000	0.996	0.004
E50-E64 Other nutritional deficiencies	0.004	0.996	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.004	0.996	0.000
L28.0 Lichen simplex chronicus	0.000	0.996	0.004
Z30.5 Surveillance of (intra-uterine) contraceptive device	0.004	0.996	0.000
C71.9 Brain, unspecified	0.004	0.996	0.000
L30.3 Infective dermatitis	0.000	0.996	0.004
L30.8 Other specified dermatitis	0.000	0.996	0.004
M70.2 Olecranon bursitis	0.004	0.996	0.000
I24.8 Other forms of acute ischaemic heart disease	0.004	0.996	0.000
I62 Other nontraumatic intracranial haemorrhage	0.004	0.996	0.000
D11.0 Parotid gland	0.004	0.996	0.000
S82.00 Fracture of patella (closed)	0.004	0.996	0.000
E89.1 Postprocedural hypoinsulinaemia	0.004	0.996	0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.004	0.996	0.000
E55 Vitamin D deficiency	0.004	0.996	0.000
E65-E68 Obesity and other hyperalimentation	0.004	0.996	0.000
L30.1 Dyshidrosis [pompholyx]	0.000	0.996	0.003
N08.3 Glomerular disorders in diabetes mellitus	0.000	0.996	0.004
L30.5 Pityriasis alba	0.000	0.996	0.003
L30.2 Cutaneous autosensitisation	0.000	0.996	0.003
I22.9 Subsequent myocardial infarction of unspecified site	0.004	0.996	0.000
T66-T78 Other and unspecified effects of external causes	0.003	0.996	0.000
L30.4 Erythema intertrigo	0.000	0.997	0.003
K35.0 Acute appendicitis with generalised peritonitis	0.000	0.997	0.003
L20.9 Atopic dermatitis, unspecified	0.000	0.997	0.003
M70.23 Olecranon bursitis-Forearm	0.003	0.997	0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.003	0.997	0.000
E61 Deficiency of other nutrient elements	0.003	0.997	0.000
E89.8 Other postprocedural endocrine and metabolic disorders	0.003	0.997	0.000
E78.4 Other hyperlipidaemia	0.003	0.997	0.000
E65 Localised adiposity	0.003	0.997	0.000
E58 Dietary calcium deficiency	0.003	0.997	0.000
E55.9 Vitamin D deficiency, unspecified	0.003	0.997	0.000
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.003	0.997	0.000
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.003	0.997	0.000
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.003	0.997	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.003	0.997	0.000
T71 Asphyxiation	0.003	0.997	0.000
E78.1 Pure hyperglyceridaemia	0.003	0.997	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.003	0.997	0.000
E63 Other nutritional deficiencies	0.003	0.997	0.000
E50 Vitamin A deficiency	0.003	0.997	0.000
E60 Dietary zinc deficiency	0.003	0.997	0.000
E59 Dietary selenium deficiency	0.003	0.997	0.000
E52 Niacin deficiency [pellagra]	0.003	0.997	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.003	0.997	0.000
E89.5 Postprocedural testicular hypofunction	0.003	0.997	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.003	0.997	0.000
M53.38 Sacrococcygeal disorders, not elsewhere classified-Sacral/s	0.003	0.997	0.000
E61.2 Magnesium deficiency	0.003	0.997	0.000
E70-E90 Metabolic disorders	0.003	0.997	0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.003	0.997	0.000
L30.0 Nummular dermatitis	0.000	0.997	0.003
Z95.4 Presence of other heart-valve replacement	0.003	0.997	0.000
E40-E46 Malnutrition	0.003	0.997	0.000
I66.3 Occlusion and stenosis of cerebellar arteries	0.003	0.997	0.000
I62.1 Nontraumatic extradural haemorrhage	0.003	0.997	0.000
E10-E14 Diabetes mellitus	0.003	0.997	0.000
E56 Other vitamin deficiencies	0.003	0.997	0.000
I67 Other cerebrovascular diseases	0.003	0.997	0.000
M70.29 Olecranon bursitis-Site unspec	0.003	0.997	0.000
M70.28 Olecranon bursitis-Other	0.003	0.997	0.000
M70.27 Olecranon bursitis-Ankle/Foot	0.003	0.997	0.000
M70.26 Olecranon bursitis-Lower Leg	0.003	0.997	0.000
M70.25 Olecranon bursitis-Pelvic/Thigh	0.003	0.997	0.000
M70.24 Olecranon bursitis-Hand	0.003	0.997	0.000
M70.21 Olecranon bursitis-Shldr region	0.003	0.997	0.000
M70.20 Olecranon bursitis-Mult sites	0.003	0.997	0.000
E89.2 Postprocedural hypoparathyroidism	0.003	0.997	0.000
E51 Thiamine deficiency	0.003	0.997	0.000
I69.0 Sequelae of subarachnoid haemorrhage	0.002	0.997	0.000
E54 Ascorbic acid deficiency	0.003	0.997	0.000
I95.2 Hypotension due to drugs	0.003	0.997	0.000
Q50.4 Embryonic cyst of Fallopian tube	0.003	0.997	0.000
E55.0 Rickets, active	0.003	0.997	0.000
T66 Unspecified effects of radiation	0.003	0.997	0.000
E78.6 Lipoprotein deficiency	0.003	0.997	0.000
E67 Other hyperalimentation	0.003	0.997	0.000
E68 Sequelae of hyperalimentation	0.003	0.997	0.000
E85.4 Organ-limited amyloidosis	0.003	0.997	0.000
E10 Insulin-dependent diabetes mellitus	0.003	0.997	0.000
T74 Maltreatment syndromes	0.003	0.997	0.000
T73 Effects of other deprivation	0.003	0.997	0.000
T69 Other effects of reduced temperature	0.003	0.997	0.000
T67 Effects of heat and light	0.003	0.997	0.000
E89.3 Postprocedural hypopituitarism	0.003	0.997	0.000
J30.3 Other allergic rhinitis	0.003	0.997	0.000
E89.4 Postprocedural ovarian failure	0.003	0.997	0.000
E61.9 Deficiency of nutrient element, unspecified	0.003	0.997	0.000
E61.8 Deficiency of other specified nutrient elements	0.003	0.997	0.000
E61.7 Deficiency of multiple nutrient elements	0.003	0.997	0.000
E61.6 Vanadium deficiency	0.003	0.997	0.000
E61.5 Molybdenum deficiency	0.003	0.997	0.000
E61.4 Chromium deficiency	0.003	0.997	0.000
E61.3 Manganese deficiency	0.003	0.997	0.000
E61.0 Copper deficiency	0.003	0.997	0.000
I66.8 Occlusion and stenosis of other cerebral artery	0.003	0.997	0.000
I66.2 Occlusion and stenosis of posterior cerebral artery	0.003	0.997	0.000
I66.1 Occlusion and stenosis of anterior cerebral artery	0.003	0.997	0.000
E85 Amyloidosis	0.003	0.997	0.000
Q66.7 Pes cavus	0.003	0.997	0.000
E72 Other disorders of amino-acid metabolism	0.003	0.997	0.000
J30 Vasomotor and allergic rhinitis	0.003	0.997	0.000
E53 Deficiency of other B group vitamins	0.003	0.997	0.000
Z96.8 Presence of other specified functional implants	0.000	0.997	0.003
V23.4 Driver injured in traffic accident	0.000	0.997	0.003
E80 Disorders of porphyrin and bilirubin metabolism	0.003	0.997	0.000
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.002	0.997	0.000
I66.0 Occlusion and stenosis of middle cerebral artery	0.002	0.997	0.000
C71.1 Frontal lobe	0.002	0.997	0.000
I67.7 Cerebral arteritis, not elsewhere classified	0.002	0.997	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.002	0.997	0.000
C45.0 Mesothelioma of pleura	0.003	0.997	0.000
E50.9 Vitamin A deficiency, unspecified	0.002	0.997	0.000
E50.8 Other manifestations of vitamin A deficiency	0.002	0.997	0.000
E50.7 Other ocular manifestations of vitamin A deficiency	0.002	0.997	0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.002	0.997	0.000
E50.5 Vitamin A deficiency with night blindness	0.002	0.997	0.000
E50.4 Vitamin A deficiency with keratomalacia	0.002	0.997	0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.002	0.997	0.000
E50.2 Vitamin A deficiency with corneal xerosis	0.002	0.997	0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.002	0.997	0.000
E50.0 Vitamin A deficiency with conjunctival xerosis	0.002	0.997	0.000
E63.9 Nutritional deficiency, unspecified	0.002	0.997	0.000
E63.8 Other specified nutritional deficiencies	0.002	0.997	0.000
E63.1 Imbalance of constituents of food intake	0.002	0.997	0.000
E63.0 Essential fatty acid [EFA] deficiency	0.002	0.997	0.000
E64.9 Sequelae of unspecified nutritional deficiency	0.002	0.997	0.000
E64.8 Sequelae of other nutritional deficiencies	0.002	0.997	0.000
E64.3 Sequelae of rickets	0.002	0.997	0.000
E64.2 Sequelae of vitamin C deficiency	0.002	0.997	0.000
E64.1 Sequelae of vitamin A deficiency	0.002	0.997	0.000
E64.0 Sequelae of protein-energy malnutrition	0.002	0.997	0.000
Q79.6 Ehlers-Danlos syndrome	0.003	0.997	0.000
Q66 Congenital deformities of feet	0.003	0.997	0.000
E15 Nondiabetic hypoglycaemic coma	0.002	0.997	0.000
E77 Disorders of glycoprotein metabolism	0.002	0.997	0.000
E76 Disorders of glycosaminoglycan metabolism	0.002	0.997	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.002	0.997	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.002	0.997	0.000
T70 Effects of air pressure and water pressure	0.002	0.997	0.000
E70 Disorders of aromatic amino-acid metabolism	0.002	0.997	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.002	0.997	0.000
E45 Retarded development following protein-energy malnutrition	0.002	0.997	0.000
E43 Unspecified severe protein-energy malnutrition	0.002	0.997	0.000
E42 Marasmic kwashiorkor	0.002	0.997	0.000
E41 Nutritional marasmus	0.002	0.997	0.000
E40 Kwashiorkor	0.002	0.997	0.000
E73 Lactose intolerance	0.002	0.997	0.000
Q78 Other osteochondrodysplasias	0.002	0.997	0.000
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.002	0.998	0.000
Z94.0 Kidney transplant status	0.000	0.998	0.002
E78.3 Hyperchylomicronaemia	0.002	0.998	0.000
E12 Malnutrition-related diabetes mellitus	0.002	0.998	0.000
S62.00 Fracture of navicular [scaphoid] bone of hand (closed)	0.000	0.998	0.002
E56.9 Vitamin deficiency, unspecified	0.002	0.998	0.000
E56.8 Deficiency of other vitamins	0.002	0.998	0.000
E56.0 Deficiency of vitamin E	0.002	0.998	0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.002	0.998	0.000
Q78.0 Osteogenesis imperfecta	0.002	0.998	0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.002	0.998	0.000
I67.5 Moyamoya disease	0.002	0.998	0.000
I67.4 Hypertensive encephalopathy	0.002	0.998	0.000
I67.3 Progressive vascular leukoencephalopathy	0.002	0.998	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.002	0.998	0.000
E51.9 Thiamine deficiency, unspecified	0.002	0.998	0.000
E51.8 Other manifestations of thiamine deficiency	0.002	0.998	0.000
E51.1 Beriberi	0.002	0.998	0.000
E85.8 Other amyloidosis	0.002	0.998	0.000
E74 Other disorders of carbohydrate metabolism	0.002	0.998	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.002	0.998	0.000
E75.2 Other sphingolipidosis	0.002	0.998	0.000
C02.9 Tongue, unspecified	0.000	0.998	0.002
Q66.9 Congenital deformity of feet, unspecified	0.002	0.998	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.002	0.998	0.000
Q66.3 Other congenital varus deformities of feet	0.002	0.998	0.000
E13 Other specified diabetes mellitus	0.002	0.998	0.000
E14.5 With peripheral circulatory complications	0.002	0.998	0.000
E67.8 Other specified hyperalimentation	0.002	0.998	0.000
E67.3 Hypervitaminosis D	0.002	0.998	0.000
E67.2 Megavitamin-B6 syndrome	0.002	0.998	0.000
E67.1 Hypercarotenaemia	0.002	0.998	0.000
E67.0 Hypervitaminosis A	0.002	0.998	0.000
E61.1 Iron deficiency	0.002	0.998	0.000
E72.0 Disorders of amino-acid transport	0.002	0.998	0.000
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified	0.002	0.998	0.000
N21.0 Calculus in bladder	0.000	0.998	0.002
E84 Cystic fibrosis	0.002	0.998	0.000
E79 Disorders of purine and pyrimidine metabolism	0.002	0.998	0.000
E80.1 Porphyria cutanea tarda	0.002	0.998	0.000
C45.9 Mesothelioma, unspecified	0.002	0.998	0.000
T67.9 Effects of heat and light, unspecified	0.002	0.998	0.000
T67.8 Other effects of heat and light	0.002	0.998	0.000
T67.7 Heat oedema	0.002	0.998	0.000
T67.6 Heat fatigue, transient	0.002	0.998	0.000
T67.5 Heat exhaustion, unspecified	0.002	0.998	0.000
T67.4 Heat exhaustion due to salt depletion	0.002	0.998	0.000
T67.3 Heat exhaustion, anhydrotic	0.002	0.998	0.000
T67.2 Heat cramp	0.002	0.998	0.000
T67.1 Heat syncope	0.002	0.998	0.000
T67.0 Heatstroke and sunstroke	0.002	0.998	0.000
T69.9 Effect of reduced temperature, unspecified	0.002	0.998	0.000
T69.8 Other specified effects of reduced temperature	0.002	0.998	0.000
T69.1 Chilblains	0.002	0.998	0.000
T69.0 Immersion hand and foot	0.002	0.998	0.000
T73.9 Effect of deprivation, unspecified	0.002	0.998	0.000
T73.8 Other effects of deprivation	0.002	0.998	0.000
T73.3 Exhaustion due to excessive exertion	0.002	0.998	0.000
T73.2 Exhaustion due to exposure	0.002	0.998	0.000
T73.1 Effects of thirst	0.002	0.998	0.000
T73.0 Effects of hunger	0.002	0.998	0.000
T74.9 Maltreatment syndrome, unspecified	0.002	0.998	0.000
T74.8 Other maltreatment syndromes	0.002	0.998	0.000
T74.3 Psychological abuse	0.002	0.998	0.000
T74.2 Sexual abuse	0.002	0.998	0.000
T74.1 Physical abuse	0.002	0.998	0.000
T74.0 Neglect or abandonment	0.002	0.998	0.000
E88 Other metabolic disorders	0.002	0.998	0.000
E56.1 Deficiency of vitamin K	0.002	0.998	0.000
Q66.6 Other congenital valgus deformities of feet	0.002	0.998	0.000
Q78.2 Osteopetrosis	0.002	0.998	0.000
S62.51 Fracture of thumb (open)	0.002	0.998	0.000
E13.3 With ophthalmic complications	0.002	0.998	0.000
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.002	0.998	0.000
Q65 Congenital deformities of hip	0.002	0.998	0.000
E72.9 Disorder of amino-acid metabolism, unspecified	0.002	0.998	0.000
E72.8 Other specified disorders of amino-acid metabolism	0.002	0.998	0.000
E72.5 Disorders of glycine metabolism	0.002	0.998	0.000
E72.4 Disorders of ornithine metabolism	0.002	0.998	0.000
E72.3 Disorders of lysine and hydroxylysine metabolism	0.002	0.998	0.000
E72.2 Disorders of urea cycle metabolism	0.002	0.998	0.000
E85.2 Heredofamilial amyloidosis, unspecified	0.002	0.998	0.000
E85.1 Neuropathic heredofamilial amyloidosis	0.002	0.998	0.000
E85.0 Nonneuropathic heredofamilial amyloidosis	0.002	0.998	0.000
Z03.4 Observation for suspected myocardial infarction	0.002	0.998	0.000
T68 Hypothermia	0.002	0.998	0.000
E53.1 Pyridoxine deficiency	0.002	0.998	0.000
E53.0 Riboflavin deficiency	0.002	0.998	0.000
E80.4 Gilbert's syndrome	0.002	0.998	0.000
H81.1 Benign paroxysmal vertigo	0.002	0.998	0.000
K73.9 Chronic hepatitis, unspecified	0.000	0.998	0.002
Q65.2 Congenital dislocation of hip, unspecified	0.002	0.998	0.000
Z50.0 Cardiac rehabilitation	0.002	0.998	0.000
E14 Unspecified diabetes mellitus	0.002	0.998	0.000
Q74 Other congenital malformations of limb(s)	0.002	0.998	0.000
T75 Effects of other external causes	0.002	0.998	0.000
E10.8 With unspecified complications	0.002	0.998	0.000
E53.8 Deficiency of other specified B group vitamins	0.002	0.998	0.000
S62.60 Fracture of other finger (closed)	0.000	0.998	0.002
E10.0 With coma	0.002	0.998	0.000
E51.2 Wernicke's encephalopathy	0.002	0.998	0.000
E80.7 Disorder of bilirubin metabolism, unspecified	0.002	0.998	0.000
E80.5 Crigler-Najjar syndrome	0.002	0.998	0.000
E80.3 Defects of catalase and peroxydase	0.002	0.998	0.000
E80.0 Hereditary erythropoietic porphyria	0.002	0.998	0.000
J30.2 Other seasonal allergic rhinitis	0.002	0.998	0.000
I67.2 Cerebral atherosclerosis	0.002	0.998	0.000
Q66.2 Metatarsus varus	0.002	0.998	0.000
C45 Mesothelioma	0.002	0.998	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.002	0.998	0.000
M13.94 Arthritis, unspecified (Hand)	0.002	0.998	0.000
E10.4 With neurological complications	0.002	0.998	0.000
E75.6 Lipid storage disorder, unspecified	0.002	0.998	0.000
E75.4 Neuronal ceroid lipofuscinosis	0.002	0.998	0.000
E75.3 Sphingolipidosis, unspecified	0.002	0.998	0.000
E75.1 Other gangliosidosis	0.002	0.998	0.000
E75.0 GM2 gangliosidosis	0.002	0.998	0.000
K46.9 Unspecified abdominal hernia without obstruction or gangrene	0.002	0.998	0.000
O63.9 Long labour, unspecified	0.002	0.998	0.000
Q66.5 Congenital pes planus	0.002	0.998	0.000
Q66.4 Talipes calcaneovalgus	0.002	0.998	0.000
Q66.1 Talipes calcaneovarus	0.002	0.998	0.000
Q68 Other congenital musculoskeletal deformities	0.002	0.998	0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.002	0.998	0.000
Q70 Syndactyly	0.002	0.998	0.000
C45.7 Mesothelioma of other sites	0.002	0.998	0.000
E71.3 Disorders of fatty-acid metabolism	0.002	0.998	0.000
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.002	0.998	0.000
E71.1 Other disorders of branched-chain amino-acid metabolism	0.002	0.998	0.000
E71.0 Maple-syrup-urine disease	0.002	0.998	0.000
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.002	0.998	0.000
E76.8 Other disorders of glucosaminoglycan metabolism	0.002	0.998	0.000
E76.3 Mucopolysaccharidosis, unspecified	0.002	0.998	0.000
E76.2 Other mucopolysaccharidoses	0.002	0.998	0.000
E76.1 Mucopolysaccharidosis, type II	0.002	0.998	0.000
E76.0 Mucopolysaccharidosis, type I	0.002	0.998	0.000
E77.9 Disorder of glycoprotein metabolism, unspecified	0.002	0.998	0.000
E77.8 Other disorders of glycoprotein metabolism	0.002	0.998	0.000
E77.1 Defects in glycoprotein degradation	0.002	0.998	0.000
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.002	0.998	0.000
G71.1 Myotonic disorders	0.000	0.998	0.002
I71.3 Abdominal aortic aneurysm, ruptured	0.002	0.998	0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.002	0.998	0.000
E70.8 Other disorders of aromatic amino-acid metabolism	0.002	0.998	0.000
E70.2 Disorders of tyrosine metabolism	0.002	0.998	0.000
E70.1 Other hyperphenylalaninaemias	0.002	0.998	0.000
E70.0 Classical phenylketonuria	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations