TreeWAS – Variant ID: rs975752

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.582	0.418	0.000
I69 Sequelae of cerebrovascular disease	0.581	0.419	0.000
I69.1 Sequelae of intracerebral haemorrhage	0.546	0.454	0.000
I60-I69 Cerebrovascular diseases	0.543	0.457	0.000
I63 Cerebral infarction	0.540	0.460	0.000
I63.9 Cerebral infarction, unspecified	0.538	0.462	0.000
I69.3 Sequelae of cerebral infarction	0.528	0.472	0.000
I62 Other nontraumatic intracranial haemorrhage	0.460	0.540	0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.432	0.568	0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.423	0.577	0.000
I63.8 Other cerebral infarction	0.421	0.578	0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.416	0.584	0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.416	0.584	0.000
I61 Intracerebral haemorrhage	0.409	0.591	0.000
I64 Stroke, not specified as haemorrhage or infarction	0.397	0.603	0.000
I68 Cerebrovascular disorders in diseases classified elsewhere	0.390	0.610	0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.390	0.610	0.000
I69.0 Sequelae of subarachnoid haemorrhage	0.388	0.612	0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.387	0.613	0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.387	0.613	0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.387	0.613	0.000
I60 Subarachnoid haemorrhage	0.377	0.623	0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.367	0.633	0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.366	0.633	0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.349	0.650	0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.337	0.663	0.000
I62.1 Nontraumatic extradural haemorrhage	0.330	0.670	0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.318	0.682	0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.312	0.688	0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.304	0.696	0.000
I61.4 Intracerebral haemorrhage in cerebellum	0.299	0.701	0.000
I61.6 Intracerebral haemorrhage, multiple localised	0.293	0.707	0.000
I61.3 Intracerebral haemorrhage in brain stem	0.293	0.707	0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.289	0.711	0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.285	0.715	0.000
I61.8 Other intracerebral haemorrhage	0.281	0.719	0.000
I61.9 Intracerebral haemorrhage, unspecified	0.280	0.720	0.000
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.279	0.720	0.000
I66.8 Occlusion and stenosis of other cerebral artery	0.279	0.720	0.000
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.279	0.720	0.000
I66.3 Occlusion and stenosis of cerebellar arteries	0.279	0.720	0.000
I66.2 Occlusion and stenosis of posterior cerebral artery	0.279	0.720	0.000
I66.1 Occlusion and stenosis of anterior cerebral artery	0.279	0.720	0.000
I66.0 Occlusion and stenosis of middle cerebral artery	0.279	0.720	0.000
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.279	0.720	0.000
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.279	0.720	0.000
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.279	0.720	0.000
I68.0 Cerebral amyloid angiopathy	0.279	0.720	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.273	0.726	0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.271	0.729	0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.271	0.729	0.000
I60.5 Subarachnoid haemorrhage from vertebral artery	0.271	0.729	0.000
I60.4 Subarachnoid haemorrhage from basilar artery	0.271	0.729	0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.271	0.729	0.000
I61.5 Intracerebral haemorrhage, intraventricular	0.271	0.729	0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.267	0.733	0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.266	0.734	0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.252	0.748	0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.251	0.749	0.000
I65.8 Occlusion and stenosis of other precerebral artery	0.251	0.749	0.000
I65.1 Occlusion and stenosis of basilar artery	0.251	0.749	0.000
I65.0 Occlusion and stenosis of vertebral artery	0.251	0.749	0.000
I60.8 Other subarachnoid haemorrhage	0.241	0.759	0.000
I67 Other cerebrovascular diseases	0.217	0.783	0.000
I67.1 Cerebral aneurysm, nonruptured	0.163	0.837	0.000
I67.2 Cerebral atherosclerosis	0.163	0.837	0.000
I67.7 Cerebral arteritis, not elsewhere classified	0.156	0.844	0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.156	0.844	0.000
I67.5 Moyamoya disease	0.156	0.844	0.000
I67.4 Hypertensive encephalopathy	0.156	0.844	0.000
I67.3 Progressive vascular leukoencephalopathy	0.156	0.844	0.000
I67.0 Dissection of cerebral arteries, nonruptured	0.151	0.849	0.000
I65.2 Occlusion and stenosis of carotid artery	0.136	0.864	0.000
I67.8 Other specified cerebrovascular diseases	0.101	0.898	0.000
I67.9 Cerebrovascular disease, unspecified	0.066	0.934	0.000
K76 Other diseases of liver	0.043	0.957	0.000
K76.0 Fatty (change of) liver, not elsewhere classified	0.042	0.958	0.000
K70-K77 Diseases of liver	0.042	0.958	0.000
K76.6 Portal hypertension	0.039	0.961	0.000
K74 Fibrosis and cirrhosis of liver	0.039	0.961	0.000
K75 Other inflammatory liver diseases	0.039	0.961	0.000
K76.9 Liver disease, unspecified	0.038	0.962	0.000
K75.9 Inflammatory liver disease, unspecified	0.038	0.962	0.000
K74.6 Other and unspecified cirrhosis of liver	0.037	0.963	0.000
K73 Chronic hepatitis, not elsewhere classified	0.036	0.964	0.000
R00.2 Palpitations	0.034	0.966	0.000
K70 Alcoholic liver disease	0.032	0.968	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.031	0.969	0.000
K76.5 Hepatic veno-occlusive disease	0.031	0.969	0.000
K76.4 Peliosis hepatis	0.031	0.969	0.000
K76.3 Infarction of liver	0.031	0.969	0.000
K76.2 Central haemorrhagic necrosis of liver	0.031	0.969	0.000
K76.1 Chronic passive congestion of liver	0.031	0.969	0.000
K75.4 Autoimmune hepatitis	0.031	0.969	0.000
K77 Liver disorders in diseases classified elsewhere	0.030	0.970	0.000
K71 Toxic liver disease	0.030	0.970	0.000
K76.7 Hepatorenal syndrome	0.029	0.971	0.000
K74.5 Biliary cirrhosis, unspecified	0.028	0.971	0.000
K74.3 Primary biliary cirrhosis	0.028	0.972	0.000
K74.4 Secondary biliary cirrhosis	0.028	0.972	0.000
K74.2 Hepatic fibrosis with hepatic sclerosis	0.028	0.972	0.000
K74.1 Hepatic sclerosis	0.028	0.972	0.000
K75.3 Granulomatous hepatitis, not elsewhere classified	0.028	0.972	0.000
K75.2 Nonspecific reactive hepatitis	0.028	0.972	0.000
K75.1 Phlebitis of portal vein	0.028	0.972	0.000
K72 Hepatic failure, not elsewhere classified	0.028	0.972	0.000
K73.9 Chronic hepatitis, unspecified	0.028	0.972	0.000
K76.8 Other specified diseases of liver	0.027	0.973	0.000
K73.8 Other chronic hepatitis, not elsewhere classified	0.026	0.974	0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.026	0.974	0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.026	0.974	0.000
K70.9 Alcoholic liver disease, unspecified	0.026	0.974	0.000
K70.3 Alcoholic cirrhosis of liver	0.026	0.974	0.000
K74.0 Hepatic fibrosis	0.025	0.975	0.000
K75.8 Other specified inflammatory liver diseases	0.025	0.975	0.000
K70.1 Alcoholic hepatitis	0.024	0.976	0.000
K75.0 Abscess of liver	0.023	0.976	0.000
K70.2 Alcoholic fibrosis and sclerosis of liver	0.023	0.977	0.000
K70.0 Alcoholic fatty liver	0.022	0.978	0.000
K71.9 Toxic liver disease, unspecified	0.022	0.978	0.000
K71.8 Toxic liver disease with other disorders of liver	0.022	0.978	0.000
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.022	0.978	0.000
K71.6 Toxic liver disease with hepatitis, not elsewhere classified	0.022	0.978	0.000
K71.5 Toxic liver disease with chronic active hepatitis	0.022	0.978	0.000
K71.4 Toxic liver disease with chronic lobular hepatitis	0.022	0.978	0.000
K71.3 Toxic liver disease with chronic persistent hepatitis	0.022	0.978	0.000
K71.2 Toxic liver disease with acute hepatitis	0.022	0.978	0.000
K71.1 Toxic liver disease with hepatic necrosis	0.022	0.978	0.000
K71.0 Toxic liver disease with cholestasis	0.022	0.978	0.000
K77.8 Liver disorders in other diseases classified elsewhere	0.022	0.978	0.000
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.022	0.978	0.000
K72.1 Chronic hepatic failure	0.020	0.980	0.000
K72.0 Acute and subacute hepatic failure	0.020	0.980	0.000
K70.4 Alcoholic hepatic failure	0.019	0.980	0.000
K72.9 Hepatic failure, unspecified	0.018	0.982	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.012	0.988	0.000
Chapter IX Diseases of the circulatory system	0.012	0.988	0.000
I99 Other and unspecified disorders of circulatory system	0.011	0.989	0.000
I98 Other disorders of circulatory system in diseases classified elsewhere	0.010	0.990	0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.010	0.990	0.000
I95 Hypotension	0.009	0.991	0.000
I95.8 Other hypotension	0.009	0.991	0.000
I00-I02 Acute rheumatic fever	0.009	0.991	0.000
I95.2 Hypotension due to drugs	0.009	0.991	0.000
I98.2 Oesophageal varices in diseases classified elsewhere	0.008	0.992	0.000
I05-I09 Chronic rheumatic heart diseases	0.008	0.992	0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.008	0.992	0.000
K35.1 Acute appendicitis with peritoneal abscess	0.008	0.992	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.008	0.992	0.000
I97.2 Postmastectomy lymphoedema syndrome	0.008	0.992	0.000
I05 Rheumatic mitral valve diseases	0.008	0.992	0.000
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.007	0.993	0.000
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.007	0.993	0.000
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.007	0.993	0.000
I98.0 Cardiovascular syphilis	0.007	0.993	0.000
I97.9 Postprocedural disorder of circulatory system, unspecified	0.007	0.993	0.000
I97.0 Postcardiotomy syndrome	0.007	0.993	0.000
I05.9 Mitral valve disease, unspecified	0.007	0.993	0.000
I95.0 Idiopathic hypotension	0.007	0.993	0.000
I97.1 Other functional disturbances following cardiac surgery	0.007	0.993	0.000
I09 Other rheumatic heart diseases	0.007	0.993	0.000
K35 Acute appendicitis	0.007	0.993	0.000
I02 Rheumatic chorea	0.006	0.993	0.000
I01 Rheumatic fever with heart involvement	0.006	0.993	0.000
I00 Rheumatic fever without mention of heart involvement	0.006	0.993	0.000
K36 Other appendicitis	0.006	0.994	0.000
I05.0 Mitral stenosis	0.006	0.994	0.000
S02.20 Fracture of nasal bones (closed)	0.006	0.994	0.000
I06 Rheumatic aortic valve diseases	0.006	0.994	0.000
O80.0 Spontaneous vertex delivery	0.006	0.994	0.000
K35.2 Acute appendicitis with generalized peritonitis	0.006	0.994	0.000
I28 Other diseases of pulmonary vessels	0.006	0.994	0.000
I05.8 Other mitral valve diseases	0.006	0.994	0.000
I07 Rheumatic tricuspid valve diseases	0.006	0.994	0.000
I09.9 Rheumatic heart disease, unspecified	0.006	0.994	0.000
I27 Other pulmonary heart diseases	0.006	0.994	0.000
T42.4 Benzodiazepines	0.000	0.994	0.006
I05.2 Mitral stenosis with insufficiency	0.005	0.994	0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.006	0.994	0.000
K35.3 Acute appendicitis with localized peritonitis	0.006	0.994	0.000
I05.1 Rheumatic mitral insufficiency	0.005	0.994	0.000
K35-K38 Diseases of appendix	0.005	0.994	0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.005	0.995	0.000
I86.4 Gastric varices	0.005	0.995	0.000
I10-I15 Hypertensive diseases	0.005	0.995	0.000
I09.8 Other specified rheumatic heart diseases	0.005	0.995	0.000
I09.2 Chronic rheumatic pericarditis	0.005	0.995	0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.005	0.995	0.000
I09.0 Rheumatic myocarditis	0.005	0.995	0.000
K35.0 Acute appendicitis with generalised peritonitis	0.005	0.995	0.000
I26 Pulmonary embolism	0.005	0.995	0.000
Z72.1 Alcohol use	0.005	0.995	0.000
I01.9 Acute rheumatic heart disease, unspecified	0.005	0.995	0.000
I01.8 Other acute rheumatic heart disease	0.005	0.995	0.000
I01.2 Acute rheumatic myocarditis	0.005	0.995	0.000
I01.1 Acute rheumatic endocarditis	0.005	0.995	0.000
I01.0 Acute rheumatic pericarditis	0.005	0.995	0.000
I02.9 Rheumatic chorea without heart involvement	0.005	0.995	0.000
I02.0 Rheumatic chorea with heart involvement	0.005	0.995	0.000
I27.9 Pulmonary heart disease, unspecified	0.005	0.995	0.000
I86 Varicose veins of other sites	0.005	0.995	0.000
R00 Abnormalities of heart beat	0.005	0.995	0.000
I27.2 Other secondary pulmonary hypertension	0.005	0.995	0.000
I83.1 Varicose veins of lower extremities with inflammation	0.005	0.995	0.000
I06.9 Rheumatic aortic valve disease, unspecified	0.004	0.995	0.000
I06.8 Other rheumatic aortic valve diseases	0.004	0.995	0.000
I06.2 Rheumatic aortic stenosis with insufficiency	0.004	0.995	0.000
I06.1 Rheumatic aortic insufficiency	0.004	0.995	0.000
I06.0 Rheumatic aortic stenosis	0.004	0.995	0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.005	0.995	0.000
I27.8 Other specified pulmonary heart diseases	0.004	0.995	0.000
I28.9 Disease of pulmonary vessels, unspecified	0.004	0.995	0.000
I28.8 Other specified diseases of pulmonary vessels	0.004	0.995	0.000
I28.1 Aneurysm of pulmonary artery	0.004	0.995	0.000
I28.0 Arteriovenous fistula of pulmonary vessels	0.004	0.995	0.000
I83 Varicose veins of lower extremities	0.005	0.995	0.000
I11 Hypertensive heart disease	0.004	0.995	0.000
K38 Other diseases of appendix	0.004	0.996	0.000
I07.9 Tricuspid valve disease, unspecified	0.004	0.996	0.000
I07.8 Other tricuspid valve diseases	0.004	0.996	0.000
I07.2 Tricuspid stenosis with insufficiency	0.004	0.996	0.000
I07.0 Tricuspid stenosis	0.004	0.996	0.000
I82 Other venous embolism and thrombosis	0.004	0.996	0.000
I27.1 Kyphoscoliotic heart disease	0.004	0.996	0.000
K35.9 Acute appendicitis, unspecified	0.004	0.996	0.000
I85 Oesophageal varices	0.004	0.996	0.000
I87 Other disorders of veins	0.004	0.996	0.000
I95.1 Orthostatic hypotension	0.004	0.996	0.000
K35.8 Acute appendicitis, other and unspecified	0.004	0.996	0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.004	0.996	0.000
I13 Hypertensive heart and renal disease	0.004	0.996	0.000
I88 Nonspecific lymphadenitis	0.004	0.996	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.004	0.996	0.000
I80 Phlebitis and thrombophlebitis	0.004	0.996	0.000
I83.0 Varicose veins of lower extremities with ulcer	0.004	0.996	0.000
I07.1 Tricuspid insufficiency	0.004	0.996	0.000
K38.1 Appendicular concretions	0.004	0.996	0.000
I81 Portal vein thrombosis	0.004	0.996	0.000
I85.9 Oesophageal varices without bleeding	0.004	0.996	0.000
I86.3 Vulval varices	0.003	0.996	0.000
I86.2 Pelvic varices	0.003	0.996	0.000
I86.0 Sublingual varices	0.003	0.996	0.000
I12 Hypertensive renal disease	0.004	0.996	0.000
I15 Secondary hypertension	0.004	0.996	0.000
I82.8 Embolism and thrombosis of other specified veins	0.004	0.996	0.000
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes	0.004	0.996	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.000	0.996	0.004
I11.0 Hypertensive heart disease with (congestive) heart failure	0.003	0.996	0.000
I87.2 Venous insufficiency (chronic) (peripheral)	0.003	0.996	0.000
K38.9 Disease of appendix, unspecified	0.003	0.997	0.000
K38.3 Fistula of appendix	0.003	0.997	0.000
K38.2 Diverticulum of appendix	0.003	0.997	0.000
K38.0 Hyperplasia of appendix	0.003	0.997	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.000	0.997	0.003
I82.3 Embolism and thrombosis of renal vein	0.003	0.997	0.000
I82.1 Thrombophlebitis migrans	0.003	0.997	0.000
I82.0 Budd-Chiari syndrome	0.003	0.997	0.000
R00.1 Bradycardia, unspecified	0.003	0.997	0.000
I82.9 Embolism and thrombosis of unspecified vein	0.003	0.997	0.000
I86.8 Varicose veins of other specified sites	0.003	0.997	0.000
I87.9 Disorder of vein, unspecified	0.003	0.997	0.000
I87.0 Postphlebitic syndrome	0.003	0.997	0.000
R00.8 Other and unspecified abnormalities of heart beat	0.003	0.997	0.000
I87.1 Compression of vein	0.003	0.997	0.000
I82.2 Embolism and thrombosis of vena cava	0.003	0.997	0.000
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified	0.003	0.997	0.000
K38.8 Other specified diseases of appendix	0.003	0.997	0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.003	0.997	0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation	0.003	0.997	0.000
I80.8 Phlebitis and thrombophlebitis of other sites	0.003	0.997	0.000
I13.9 Hypertensive heart and renal disease, unspecified	0.003	0.997	0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.003	0.997	0.000
I13.1 Hypertensive heart and renal disease with renal failure	0.003	0.997	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.003	0.997	0.000
K37 Unspecified appendicitis	0.003	0.997	0.000
I12.9 Hypertensive renal disease without renal failure	0.003	0.997	0.000
I88.8 Other nonspecific lymphadenitis	0.003	0.997	0.000
I88.1 Chronic lymphadenitis, except mesenteric	0.003	0.997	0.000
I88.0 Nonspecific mesenteric lymphadenitis	0.003	0.997	0.000
I87.8 Other specified disorders of veins	0.003	0.997	0.000
I89.1 Lymphangitis	0.003	0.997	0.000
S02.2 Fracture of nasal bones	0.003	0.997	0.000
J45.9 Asthma, unspecified	0.000	0.997	0.003
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.000	0.997	0.003
I70-I79 Diseases of arteries, arterioles and capillaries	0.003	0.997	0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site	0.003	0.997	0.000
I15.9 Seconday hypertension, unspecified	0.003	0.997	0.000
I15.8 Other secondary hypertension	0.003	0.997	0.000
I15.2 Hypertension secondary to endocrine disorders	0.003	0.997	0.000
I15.0 Renovascular hypertension	0.003	0.997	0.000
I71.3 Abdominal aortic aneurysm, ruptured	0.003	0.997	0.000
I85.0 Oesophageal varices with bleeding	0.003	0.997	0.000
I88.9 Nonspecific lymphadenitis, unspecified	0.003	0.997	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.000	0.997	0.003
T42.5 Mixed antiepileptics, not elsewhere classified	0.000	0.997	0.003
T42.3 Barbiturates	0.000	0.997	0.003
T42.2 Succinimides and oxazolidinediones	0.000	0.997	0.003
T42.0 Hydantoin derivatives	0.000	0.997	0.003
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.000	0.997	0.003
T43.5 Other and unspecified antipsychotics and neuroleptics	0.000	0.997	0.003
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.000	0.997	0.002
I15.1 Hypertension secondary to other renal disorders	0.002	0.997	0.000
I89.0 Lymphoedema, not elsewhere classified	0.002	0.997	0.000
T42.1 Iminostilbenes	0.000	0.997	0.002
I73 Other peripheral vascular diseases	0.002	0.997	0.000
S02.21 Fracture of nasal bones (open)	0.002	0.998	0.000
W06.0 Home	0.002	0.998	0.000
I73.9 Peripheral vascular disease, unspecified	0.002	0.998	0.000
M67.8 Other specified disorders of synovium and tendon	0.002	0.998	0.000
O80 Single spontaneous delivery	0.002	0.998	0.000
J38.7 Other diseases of larynx	0.000	0.998	0.002
N85.9 Noninflammatory disorder of uterus, unspecified	0.000	0.998	0.002
T36-T50 Poisoning by drugs, medicaments and biological substances	0.000	0.998	0.002
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.002	0.998	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.998	0.002
I86.1 Scrotal varices	0.002	0.998	0.001
I27.0 Primary pulmonary hypertension	0.002	0.998	0.000
T43.9 Psychotropic drug, unspecified	0.000	0.998	0.002
T43.8 Other psychotropic drugs, not elsewhere classified	0.000	0.998	0.002
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.998	0.002
N85.8 Other specified noninflammatory disorders of uterus	0.000	0.998	0.002
I71 Aortic aneurysm and dissection	0.002	0.998	0.000
I77.9 Disorder of arteries and arterioles, unspecified	0.002	0.998	0.000
I12.0 Hypertensive renal disease with renal failure	0.002	0.998	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.002	0.998	0.000
I77 Other disorders of arteries and arterioles	0.002	0.998	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.998	0.002
N03.9 Unspecified	0.002	0.998	0.000
I70 Atherosclerosis	0.002	0.998	0.000
M47.99 Spondylosis, unspecified (Site unspecified)	0.000	0.998	0.002
I73.1 Thromboangiitis obliterans [Buerger]	0.002	0.998	0.000
I73.8 Other specified peripheral vascular diseases	0.002	0.998	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.000	0.998	0.002
S72.10 Pertrochanteric fracture (closed)	0.000	0.998	0.002
T43.6 Psychostimulants with abuse potential	0.000	0.998	0.002
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.998	0.002
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.000	0.998	0.002
I77.8 Other specified disorders of arteries and arterioles	0.002	0.998	0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.002	0.998	0.000
O80.1 Spontaneous breech delivery	0.002	0.998	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.998	0.002
O80.8 Other single spontaneous delivery	0.002	0.998	0.000
I72 Other aneurysm	0.002	0.998	0.000
N85.2 Hypertrophy of uterus	0.000	0.998	0.002
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.000	0.998	0.002
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.998	0.002
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.000	0.998	0.002
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.000	0.998	0.002
T41 Poisoning by anaesthetics and therapeutic gases	0.000	0.998	0.002
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.000	0.998	0.002
I78 Diseases of capillaries	0.002	0.998	0.000
N85 Other noninflammatory disorders of uterus, except cervix	0.000	0.998	0.002
I71.8 Aortic aneurysm of unspecified site, ruptured	0.002	0.998	0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.002	0.998	0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.002	0.998	0.000
I71.1 Thoracic aortic aneurysm, ruptured	0.002	0.998	0.000
I72.9 Aneurysm of unspecified site	0.002	0.998	0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.002	0.998	0.000
Z75.1 Person awaiting admission to adequate facility elsewhere	0.002	0.998	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.002	0.998	0.000
I77.5 Necrosis of artery	0.002	0.998	0.000
I77.4 Coeliac artery compression syndrome	0.002	0.998	0.000
I77.3 Arterial fibromuscular dysplasia	0.002	0.998	0.000
I77.2 Rupture of artery	0.002	0.998	0.000
N85.0 Endometrial glandular hyperplasia	0.000	0.998	0.002
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.002	0.998	0.000
I79.1 Aortitis in diseases classified elsewhere	0.002	0.998	0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.002	0.998	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.000	0.998	0.002
D26.1 Corpus uteri	0.002	0.998	0.000
Z75.3 Unavailability and inaccessibility of health-care facilities	0.002	0.998	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.000	0.998	0.002
T36 Poisoning by systemic antibiotics	0.000	0.998	0.002
I70.9 Generalised and unspecified atherosclerosis	0.002	0.998	0.000
I70.8 Atherosclerosis of other arteries	0.002	0.998	0.000
I70.1 Atherosclerosis of renal artery	0.002	0.998	0.000
I77.0 Arteriovenous fistula, acquired	0.002	0.998	0.000
Z03.8 Observation for other suspected diseases and conditions	0.002	0.998	0.000
T45.0 Antiallergic and antiemetic drugs	0.000	0.998	0.002
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.998	0.002
T46.8 Antivaricose drugs, including sclerosing agents	0.000	0.998	0.002
T46.7 Peripheral vasodilators	0.000	0.998	0.002
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.998	0.002
T46.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.998	0.002
T46.3 Coronary vasodilators, not elsewhere classified	0.000	0.998	0.002
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.998	0.002
T46.1 Calcium-channel blockers	0.000	0.998	0.002
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.998	0.002
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.998	0.002
Z74.0 Reduced mobility	0.002	0.998	0.000
Z75 Problems related to medical facilities and other health care	0.002	0.998	0.000
Z72 Problems related to lifestyle	0.002	0.998	0.000
I70.0 Atherosclerosis of aorta	0.001	0.998	0.000
T38.9 Other and unspecified hormone antagonists	0.000	0.998	0.001
T38.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.998	0.001
T38.7 Androgens and anabolic congeners	0.000	0.998	0.001
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.000	0.998	0.001
T38.5 Other oestrogens and progestogens	0.000	0.998	0.001
T38.4 Oral contraceptives	0.000	0.998	0.001
T38.2 Antithyroid drugs	0.000	0.998	0.001
T38.1 Thyroid hormones and substitutes	0.000	0.998	0.001
T38.0 Glucocorticoids and synthetic analogues	0.000	0.998	0.001
T45.9 Primarily systemic and haematological agent, unspecified	0.000	0.998	0.001
T45.8 Other primarily systemic and haematological agents	0.000	0.998	0.001
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.000	0.998	0.001
T45.6 Fibrinolysis-affecting drugs	0.000	0.998	0.001
T45.5 Anticoagulants	0.000	0.998	0.001
T45.4 Iron and its compounds	0.000	0.998	0.001
T45.3 Enzymes, not elsewhere classified	0.000	0.998	0.001
T45.2 Vitamins, not elsewhere classified	0.000	0.998	0.001
T45.1 Antineoplastic and immunosuppressive drugs	0.000	0.998	0.001
I71.0 Dissection of aorta [any part]	0.001	0.998	0.000
I72.6 Aneurysm and dissection of vertebral artery	0.001	0.998	0.000
I72.5 Aneurysm and dissection of other precerebral arteries	0.001	0.998	0.000
I72.2 Aneurysm of renal artery	0.001	0.998	0.000
I72.1 Aneurysm of artery of upper extremity	0.001	0.998	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.000	0.998	0.001
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.000	0.998	0.001
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.998	0.001
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.000	0.998	0.001
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.000	0.998	0.001
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.000	0.998	0.001
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.000	0.998	0.001
T44.1 Other parasympathomimetics [cholinergics]	0.000	0.998	0.001
T44.0 Anticholinesterase agents	0.000	0.998	0.001
S82.50 Fracture of medial malleolus (closed)	0.002	0.998	0.000
I72.8 Aneurysm of other specified arteries	0.001	0.998	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.000	0.998	0.001
T37.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.998	0.001
T37.5 Antiviral drugs	0.000	0.998	0.001
T37.4 Anthelminthics	0.000	0.998	0.001
T37.3 Other antiprotozoal drugs	0.000	0.998	0.001
T37.2 Antimalarials and drugs acting on other blood protozoa	0.000	0.998	0.001
T37.1 Antimycobacterial drugs	0.000	0.998	0.001
T37.0 Sulphonamides	0.000	0.998	0.001
T41.5 Therapeutic gases	0.000	0.998	0.001
T41.4 Anaesthetic, unspecified	0.000	0.998	0.001
T41.3 Local anaesthetics	0.000	0.998	0.001
T41.2 Other and unspecified general anaesthetics	0.000	0.998	0.001
T41.1 Intravenous anaesthetics	0.000	0.998	0.001
T41.0 Inhaled anaesthetics	0.000	0.998	0.001
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.998	0.002
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.000	0.998	0.001
T47.8 Other agents primarily affecting the gastro-intestinal system	0.000	0.998	0.001
T47.7 Emetics	0.000	0.998	0.001
T47.6 Antidiarrhoeal drugs	0.000	0.998	0.001
T47.5 Digestants	0.000	0.998	0.001
T47.4 Other laxatives	0.000	0.998	0.001
T47.3 Saline and osmotic laxatives	0.000	0.998	0.001
T47.2 Stimulant laxatives	0.000	0.998	0.001
T47.1 Other antacids and anti-gastric-secretion drugs	0.000	0.998	0.001
T47.0 Histamine H(2)-receptor antagonists	0.000	0.998	0.001
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.000	0.998	0.001
T48.6 Antiasthmatics, not elsewhere classified	0.000	0.998	0.001
T48.5 Anti-common-cold drugs	0.000	0.998	0.001
T48.4 Expectorants	0.000	0.998	0.001
T48.3 Antitussives	0.000	0.998	0.001
T48.2 Other and unspecified agents primarily acting on muscles	0.000	0.998	0.001
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.000	0.998	0.001
T48.0 Oxytocic drugs	0.000	0.998	0.001
T49.9 Topical agent, unspecified	0.000	0.998	0.001
T49.8 Other topical agents	0.000	0.998	0.001
T49.7 Dental drugs, topically applied	0.000	0.998	0.001
T49.6 Otorhinolaryngological drugs and preparations	0.000	0.998	0.001
T49.5 Ophthalmological drugs and preparations	0.000	0.998	0.001
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.000	0.998	0.001
T49.3 Emollients, demulcents and protectants	0.000	0.998	0.001
T49.2 Local astringents and local detergents	0.000	0.998	0.001
T49.1 Antipruritics	0.000	0.998	0.001
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.000	0.998	0.001
I08 Multiple valve diseases	0.001	0.998	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.000	0.998	0.002
I78.9 Disease of capillaries, unspecified	0.001	0.998	0.000
I78.8 Other diseases of capillaries	0.001	0.998	0.000
C67.9 Bladder, unspecified	0.000	0.998	0.002
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.000	0.998	0.002
M41.99 Scoliosis, unspecified (Site unspecified)	0.000	0.998	0.002
N85.7 Haematometra	0.000	0.998	0.001
N85.5 Inversion of uterus	0.000	0.998	0.001
N85.3 Subinvolution of uterus	0.000	0.998	0.001
T43.2 Other and unspecified antidepressants	0.000	0.998	0.002
Z72.8 Other problems related to lifestyle	0.002	0.998	0.000
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.002	0.998	0.000
C67.4 Posterior wall of bladder	0.000	0.998	0.002
J69.0 Pneumonitis due to food and vomit	0.002	0.998	0.000
N85.6 Intra-uterine synechiae	0.000	0.998	0.002
T39.1 4-Aminophenol derivatives	0.000	0.998	0.002
C67.2 Lateral wall of bladder	0.000	0.998	0.002
K22.9 Disease of oesophagus, unspecified	0.000	0.998	0.002
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.001	0.998	0.000
I70.11 Atherosclerosis of renal artery (with gangrene)	0.001	0.998	0.000
I70.10 Atherosclerosis of renal artery (without gangrene)	0.001	0.998	0.000
I70.81 Atherosclerosis of other arteries (with gangrene)	0.001	0.998	0.000
I70.80 Atherosclerosis of other arteries (without gangrene)	0.001	0.998	0.000
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.001	0.998	0.000
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.001	0.998	0.000
M48.06 Spinal stenosis (Lumbar region)	0.000	0.998	0.002
I73.0 Raynaud's syndrome	0.002	0.998	0.000
T36.9 Systemic antibiotic, unspecified	0.000	0.998	0.001
T36.8 Other systemic antibiotics	0.000	0.998	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations