TreeWAS – Variant ID: rs9772809

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
S82.10 Fracture of upper end of tibia (closed)	0.000	0.992	0.008
K51.9 Ulcerative colitis, unspecified	0.000	0.992	0.008
S82.1 Fracture of upper end of tibia	0.000	0.993	0.007
M81.99 Osteoporosis, unspecified (Site unspecified)	0.000	0.994	0.006
K60.3 Anal fistula	0.000	0.994	0.006
C18.9 Colon, unspecified	0.006	0.994	0.000
S82 Fracture of lower leg, including ankle	0.000	0.994	0.006
S82.11 Fracture of upper end of tibia (open)	0.000	0.995	0.005
S82.2 Fracture of shaft of tibia	0.000	0.995	0.005
M81.9 Osteoporosis, unspecified	0.000	0.995	0.005
S82.7 Multiple fractures of lower leg	0.000	0.995	0.005
S82.4 Fracture of fibula alone	0.000	0.995	0.004
S82.3 Fracture of lower end of tibia	0.000	0.996	0.004
S82.0 Fracture of patella	0.000	0.996	0.004
S82.9 Fracture of lower leg, part unspecified	0.000	0.996	0.004
S82.5 Fracture of medial malleolus	0.000	0.996	0.004
S82.20 Fracture of shaft of tibia (closed)	0.000	0.996	0.004
C18 Malignant neoplasm of colon	0.004	0.996	0.000
S82.21 Fracture of shaft of tibia (open)	0.000	0.996	0.004
M81.90 Osteoporosis, unspecified (Multiple sites)	0.000	0.996	0.004
S81 Open wound of lower leg	0.000	0.996	0.004
S80-S89 Injuries to the knee and lower leg	0.000	0.996	0.004
S82.70 Multiple fractures of lower leg (closed)	0.000	0.996	0.004
S82.6 Fracture of lateral malleolus	0.000	0.996	0.004
S82.40 Fracture of fibula alone (closed)	0.000	0.996	0.004
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.000	0.996	0.004
S82.30 Fracture of lower end of tibia (closed)	0.000	0.996	0.004
K51.2 Ulcerative (chronic) proctitis	0.000	0.996	0.004
S81.9 Open wound of lower leg, part unspecified	0.000	0.996	0.004
K51 Ulcerative colitis	0.000	0.996	0.004
S82.00 Fracture of patella (closed)	0.000	0.996	0.004
S81.8 Open wound of other parts of lower leg	0.000	0.996	0.004
M81.91 Osteoporosis, unspecified (Shoulder region)	0.000	0.996	0.004
M81.96 Osteoporosis, unspecified (Lower leg)	0.000	0.996	0.004
M81.94 Osteoporosis, unspecified (Hand)	0.000	0.996	0.004
M81.98 Osteoporosis, unspecified (Other)	0.000	0.996	0.004
C18.2 Ascending colon	0.004	0.996	0.000
S82.71 Multiple fractures of lower leg (open)	0.000	0.996	0.003
M81.92 Osteoporosis, unspecified (Upper arm)	0.000	0.996	0.003
S82.41 Fracture of fibula alone (open)	0.000	0.996	0.003
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.000	0.996	0.003
M81.93 Osteoporosis, unspecified (Forearm)	0.000	0.996	0.003
C18.0 Caecum	0.003	0.996	0.000
S82.50 Fracture of medial malleolus (closed)	0.000	0.997	0.003
S82.91 Fracture of lower leg, part unspecified (open)	0.000	0.997	0.003
C18.3 Hepatic flexure	0.003	0.997	0.000
C18.4 Transverse colon	0.003	0.997	0.000
S82.90 Fracture of lower leg, part unspecified (closed)	0.000	0.997	0.003
C18.1 Appendix	0.003	0.997	0.000
S82.01 Fracture of patella (open)	0.000	0.997	0.003
S82.31 Fracture of lower end of tibia (open)	0.000	0.997	0.003
C18.5 Splenic flexure	0.003	0.997	0.000
S80 Superficial injury of lower leg	0.000	0.997	0.003
S89 Other and unspecified injuries of lower leg	0.000	0.997	0.003
S81.0 Open wound of knee	0.000	0.997	0.003
S87 Crushing injury of lower leg	0.000	0.997	0.003
N60.4 Mammary duct ectasia	0.003	0.997	0.000
C18.6 Descending colon	0.003	0.997	0.000
K51.0 Ulcerative (chronic) enterocolitis	0.000	0.997	0.003
S82.51 Fracture of medial malleolus (open)	0.000	0.997	0.003
N60 Benign mammary dysplasia	0.003	0.997	0.000
N60.0 Solitary cyst of breast	0.003	0.997	0.000
S88 Traumatic amputation of lower leg	0.000	0.997	0.003
S82.61 Fracture of lateral malleolus (open)	0.000	0.997	0.003
S85 Injury of blood vessels at lower leg level	0.000	0.997	0.003
S84 Injury of nerves at lower leg level	0.000	0.997	0.003
S86 Injury of muscle and tendon at lower leg level	0.000	0.997	0.003
M81 Osteoporosis without pathological fracture	0.000	0.997	0.003
S81.7 Multiple open wounds of lower leg	0.000	0.997	0.003
C18.8 Overlapping lesion of colon	0.003	0.997	0.000
C18.7 Sigmoid colon	0.003	0.997	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.000	0.997	0.003
S80.9 Superficial injury of lower leg, unspecified	0.000	0.997	0.003
K51.1 Ulcerative (chronic) ileocolitis	0.000	0.997	0.003
S80.7 Multiple superficial injuries of lower leg	0.000	0.997	0.003
S89.9 Unspecified injury of lower leg	0.000	0.997	0.003
N60.3 Fibrosclerosis of breast	0.003	0.997	0.000
S82.8 Fractures of other parts of lower leg	0.000	0.997	0.003
K51.5 Mucosal proctocolitis	0.000	0.997	0.003
N60.1 Diffuse cystic mastopathy	0.003	0.997	0.000
N60.8 Other benign mammary dysplasias	0.003	0.997	0.000
S87.8 Crushing injury of other and unspecified parts of lower leg	0.000	0.997	0.003
S82.60 Fracture of lateral malleolus (closed)	0.000	0.997	0.003
S80.1 Contusion of other and unspecified parts of lower leg	0.000	0.997	0.003
H92.1 Otorrhoea	0.000	0.997	0.003
C20 Malignant neoplasm of rectum	0.003	0.997	0.000
M81.2 Osteoporosis of disuse	0.000	0.997	0.003
S89.7 Multiple injuries of lower leg	0.000	0.997	0.002
S89.1 Other specified injuries of lower leg	0.000	0.997	0.002
S89.0 Multiple injuries of lower leg	0.000	0.997	0.002
K51.4 Pseudopolyposis of colon	0.000	0.997	0.002
S87.0 Crushing injury of knee	0.000	0.997	0.002
S83.3 Tear of articular cartilage of knee, current	0.000	0.997	0.002
M75.1 Rotator cuff syndrome	0.003	0.997	0.000
M81.3 Postsurgical malabsorption osteoporosis	0.000	0.997	0.002
N60.9 Benign mammary dysplasia, unspecified	0.002	0.997	0.000
N60.2 Fibroadenosis of breast	0.003	0.997	0.000
S89.8 Other specified injuries of lower leg	0.000	0.997	0.002
K60 Fissure and fistula of anal and rectal regions	0.000	0.997	0.003
S86.2 Injury of muscle(s) and tendon(s) of anterior muscle group at lower leg level	0.000	0.997	0.002
S88.9 Traumatic amputation of lower leg, level unspecified	0.000	0.997	0.002
S88.1 Traumatic amputation at level between knee and ankle	0.000	0.997	0.002
S88.0 Traumatic amputation at knee level	0.000	0.997	0.002
S80.0 Contusion of knee	0.000	0.997	0.002
S83.7 Injury to multiple structures of knee	0.000	0.997	0.002
S85.9 Injury of unspecified blood vessel at lower leg level	0.000	0.997	0.002
S85.8 Injury of other blood vessels at lower leg level	0.000	0.997	0.002
S85.7 Injury of multiple blood vessels at lower leg level	0.000	0.997	0.002
S85.5 Injury of popliteal vein	0.000	0.997	0.002
S85.4 Injury of lesser saphenous vein at lower leg level	0.000	0.997	0.002
S85.3 Injury of greater saphenous vein at lower leg level	0.000	0.997	0.002
S85.2 Injury of peroneal artery	0.000	0.997	0.002
S85.0 Injury of popliteal artery	0.000	0.997	0.002
K51.8 Other ulcerative colitis	0.000	0.997	0.002
S84.9 Injury of unspecified nerve at lower leg level	0.000	0.997	0.002
S84.8 Injury of other nerves at lower leg level	0.000	0.997	0.002
S84.7 Injury of multiple nerves at lower leg level	0.000	0.997	0.002
S84.2 Injury of cutaneous sensory nerve at lower leg level	0.000	0.997	0.002
S84.0 Injury of tibial nerve at lower leg level	0.000	0.997	0.002
S86.3 Injury of muscle(s) and tendon(s) of peroneal muscle group at lower leg level	0.000	0.997	0.002
S85.1 Injury of (anterior)(posterior) tibial artery	0.000	0.997	0.002
S84.1 Injury of peroneal nerve at lower leg level	0.000	0.998	0.002
S86.0 Injury of Achilles tendon	0.000	0.998	0.002
S86.7 Injury of multiple muscles and tendons at lower leg level	0.000	0.998	0.002
S86.1 Injury of other muscle(s) and tendon(s) of posterior muscle group at lower leg level	0.000	0.998	0.002
M81.8 Other osteoporosis	0.000	0.998	0.002
M81.6 Localised osteoporosis [Lequesne]	0.000	0.998	0.002
M81.5 Idiopathic osteoporosis	0.000	0.998	0.002
M81.0 Postmenopausal osteoporosis	0.000	0.998	0.002
M81.20 Osteoporosis of disuse (Multiple sites)	0.000	0.998	0.002
K51.3 Ulcerative (chronic) rectosigmoiditis	0.000	0.998	0.002
M81.1 Postoophorectomy osteoporosis	0.000	0.998	0.002
S83.0 Dislocation of patella	0.000	0.998	0.002
S86.9 Injury of unspecified muscle and tendon at lower leg level	0.000	0.998	0.002
M81.4 Drug-induced osteoporosis	0.000	0.998	0.002
E16.2 Hypoglycaemia, unspecified	0.000	0.998	0.002
S80.8 Other superficial injuries of lower leg	0.000	0.998	0.002
S86.8 Injury of other muscles and tendons at lower leg level	0.000	0.998	0.002
S83.1 Dislocation of knee	0.000	0.998	0.002
S82.86 Maisonneuve's fracture	0.000	0.998	0.002
M81.30 Postsurgical malabsorption osteoporosis (Multiple sites)	0.000	0.998	0.002
K60.5 Anorectal fistula	0.000	0.998	0.002
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.000	0.998	0.002
O36.8 Maternal care for other specified foetal problems	0.002	0.998	0.000
G56.0 Carpal tunnel syndrome	0.002	0.998	0.000
S83.6 Sprain and strain of other and unspecified parts of knee	0.000	0.998	0.002
K60.4 Rectal fistula	0.000	0.998	0.002
K21.0 Gastro-oesophageal reflux disease with oesophagitis	0.002	0.998	0.000
H92 Otalgia and effusion of ear	0.000	0.998	0.002
M81.29 Osteoporosis of disuse (Site unspecified)	0.000	0.998	0.002
M81.28 Osteoporosis of disuse (Other)	0.000	0.998	0.002
M81.27 Osteoporosis of disuse (Ankle and foot)	0.000	0.998	0.002
M81.26 Osteoporosis of disuse (Lower leg)	0.000	0.998	0.002
M81.25 Osteoporosis of disuse (Pelvic region and thigh)	0.000	0.998	0.002
M81.24 Osteoporosis of disuse (Hand)	0.000	0.998	0.002
M81.23 Osteoporosis of disuse (Forearm)	0.000	0.998	0.002
M81.22 Osteoporosis of disuse (Upper arm)	0.000	0.998	0.002
M81.21 Osteoporosis of disuse (Shoulder region)	0.000	0.998	0.002
S83.2 Tear of meniscus, current	0.000	0.998	0.002
C15-C26 Malignant neoplasms of digestive organs	0.002	0.998	0.000
M81.39 Postsurgical malabsorption osteoporosis (Site unspecified)	0.000	0.998	0.002
M81.38 Postsurgical malabsorption osteoporosis (Other)	0.000	0.998	0.002
M81.37 Postsurgical malabsorption osteoporosis (Ankle and foot)	0.000	0.998	0.002
M81.36 Postsurgical malabsorption osteoporosis (Lower leg)	0.000	0.998	0.002
M81.35 Postsurgical malabsorption osteoporosis (Pelvic region and thigh)	0.000	0.998	0.002
M81.34 Postsurgical malabsorption osteoporosis (Hand)	0.000	0.998	0.002
M81.33 Postsurgical malabsorption osteoporosis (Forearm)	0.000	0.998	0.002
M81.32 Postsurgical malabsorption osteoporosis (Upper arm)	0.000	0.998	0.002
M81.31 Postsurgical malabsorption osteoporosis (Shoulder region)	0.000	0.998	0.002
S82.81 Fractures of other parts of lower leg (open)	0.000	0.998	0.002
M81.09 Postmenopausal osteoporosis (Site unspecified)	0.000	0.998	0.002
M81.89 Other osteoporosis (Site unspecified)	0.000	0.998	0.002
H92.0 Otalgia	0.000	0.998	0.002
K60.0 Acute anal fissure	0.000	0.998	0.002
M81.08 Postmenopausal osteoporosis (Other)	0.000	0.998	0.002
M81.07 Postmenopausal osteoporosis (Ankle and foot)	0.000	0.998	0.002
M81.06 Postmenopausal osteoporosis (Lower leg)	0.000	0.998	0.002
M81.05 Postmenopausal osteoporosis (Pelvic region and thigh)	0.000	0.998	0.002
M81.04 Postmenopausal osteoporosis (Hand)	0.000	0.998	0.002
M81.03 Postmenopausal osteoporosis (Forearm)	0.000	0.998	0.002
M81.02 Postmenopausal osteoporosis (Upper arm)	0.000	0.998	0.002
M81.01 Postmenopausal osteoporosis (Shoulder region)	0.000	0.998	0.002
M81.88 Other osteoporosis (Other)	0.000	0.998	0.002
M81.87 Other osteoporosis (Ankle and foot)	0.000	0.998	0.002
M81.86 Other osteoporosis (Lower leg)	0.000	0.998	0.002
M81.85 Other osteoporosis (Pelvic region and thigh)	0.000	0.998	0.002
M81.84 Other osteoporosis (Hand)	0.000	0.998	0.002
M81.83 Other osteoporosis (Forearm)	0.000	0.998	0.002
M81.82 Other osteoporosis (Upper arm)	0.000	0.998	0.002
M81.81 Other osteoporosis (Shoulder region)	0.000	0.998	0.002
S86.00 Unspecified injury of Achilles tendon	0.000	0.998	0.002
M75.0 Adhesive capsulitis of shoulder	0.002	0.998	0.000
M81.59 Idiopathic osteoporosis (Site unspecified)	0.000	0.998	0.002
M81.58 Idiopathic osteoporosis (Other)	0.000	0.998	0.002
M81.57 Idiopathic osteoporosis (Ankle and foot)	0.000	0.998	0.002
M81.56 Idiopathic osteoporosis (Lower leg)	0.000	0.998	0.002
M81.55 Idiopathic osteoporosis (Pelvic region and thigh)	0.000	0.998	0.002
M81.54 Idiopathic osteoporosis (Hand)	0.000	0.998	0.002
M81.53 Idiopathic osteoporosis (Forearm)	0.000	0.998	0.002
M81.52 Idiopathic osteoporosis (Upper arm)	0.000	0.998	0.002
M81.51 Idiopathic osteoporosis (Shoulder region)	0.000	0.998	0.002
M81.50 Idiopathic osteoporosis (Multiple sites)	0.000	0.998	0.002
M81.69 Localized osteoporosis [Lequesne] (Site unspecified)	0.000	0.998	0.002
M81.68 Localized osteoporosis [Lequesne] (Other)	0.000	0.998	0.002
M81.67 Localized osteoporosis [Lequesne] (Ankle and foot)	0.000	0.998	0.002
M81.66 Localized osteoporosis [Lequesne] (Lower leg)	0.000	0.998	0.002
M81.65 Localized osteoporosis [Lequesne] (Pelvic region and thigh)	0.000	0.998	0.002
M81.64 Localized osteoporosis [Lequesne] (Hand)	0.000	0.998	0.002
M81.63 Localized osteoporosis [Lequesne] (Forearm)	0.000	0.998	0.002
M81.62 Localized osteoporosis [Lequesne] (Upper arm)	0.000	0.998	0.002
M81.61 Localized osteoporosis [Lequesne] (Shoulder region)	0.000	0.998	0.002
M81.60 Localized osteoporosis [Lequesne] (Multiple sites)	0.000	0.998	0.002
M81.00 Postmenopausal osteoporosis (Multiple sites)	0.000	0.998	0.002
M81.19 Postoophorectomy osteoporosis (Site unspecified)	0.000	0.998	0.002
M81.18 Postoophorectomy osteoporosis (Other)	0.000	0.998	0.002
M81.17 Postoophorectomy osteoporosis (Ankle and foot)	0.000	0.998	0.002
M81.16 Postoophorectomy osteoporosis (Lower leg)	0.000	0.998	0.002
M81.15 Postoophorectomy osteoporosis (Pelvic region and thigh)	0.000	0.998	0.002
M81.14 Postoophorectomy osteoporosis (Hand)	0.000	0.998	0.002
M81.13 Postoophorectomy osteoporosis (Forearm)	0.000	0.998	0.002
M81.12 Postoophorectomy osteoporosis (Upper arm)	0.000	0.998	0.002
M81.11 Postoophorectomy osteoporosis (Shoulder region)	0.000	0.998	0.002
M81.80 Other osteoporosis (Multiple sites)	0.000	0.998	0.002
K60.2 Anal fissure, unspecified	0.000	0.998	0.002
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.000	0.998	0.002
C26 Malignant neoplasm of other and ill-defined digestive organs	0.002	0.998	0.000
M81.10 Postoophorectomy osteoporosis (Multiple sites)	0.000	0.998	0.002
M81.49 Drug-induced osteoporosis (Site unspecified)	0.000	0.998	0.002
M81.48 Drug-induced osteoporosis (Other)	0.000	0.998	0.002
M81.47 Drug-induced osteoporosis (Ankle and foot)	0.000	0.998	0.002
M81.46 Drug-induced osteoporosis (Lower leg)	0.000	0.998	0.002
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)	0.000	0.998	0.002
M81.44 Drug-induced osteoporosis (Hand)	0.000	0.998	0.002
M81.43 Drug-induced osteoporosis (Forearm)	0.000	0.998	0.002
M81.42 Drug-induced osteoporosis (Upper arm)	0.000	0.998	0.002
M81.41 Drug-induced osteoporosis (Shoulder region)	0.000	0.998	0.002
C26.0 Intestinal tract, part unspecified	0.002	0.998	0.000
H92.2 Otorrhagia	0.000	0.998	0.002
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.002	0.998	0.000
C21 Malignant neoplasm of anus and anal canal	0.002	0.998	0.000
M81.40 Drug-induced osteoporosis (Multiple sites)	0.000	0.998	0.002
C21.0 Anus, unspecified	0.002	0.998	0.000
M75 Shoulder lesions	0.002	0.998	0.000
C24.1 Ampulla of Vater	0.002	0.998	0.000
C17 Malignant neoplasm of small intestine	0.002	0.998	0.000
M19.01 Primary arthrosis of other joints (Shoulder region)	0.000	0.998	0.002
C24.0 Extrahepatic bile duct	0.002	0.998	0.000
C21.1 Anal canal	0.002	0.998	0.000
K60.1 Chronic anal fissure	0.000	0.998	0.002
E16 Other disorders of pancreatic internal secretion	0.000	0.998	0.002
C23 Malignant neoplasm of gallbladder	0.002	0.998	0.000
C26.8 Overlapping lesion of digestive system	0.002	0.998	0.000
C26.1 Spleen	0.002	0.998	0.000
M75.5 Bursitis of shoulder	0.002	0.998	0.000
O80.9 Single spontaneous delivery, unspecified	0.002	0.998	0.000
Y44.2 Anticoagulants	0.000	0.998	0.002
E16.1 Other hypoglycaemia	0.000	0.998	0.002
N87.1 Moderate cervical dysplasia	0.000	0.998	0.002
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.002	0.998	0.000
C21.2 Cloacogenic zone	0.001	0.998	0.000
C24.8 Overlapping lesion of biliary tract	0.001	0.998	0.000
C26.9 Ill-defined sites within the digestive system	0.001	0.998	0.000
H93.8 Other specified disorders of ear	0.000	0.998	0.002
H93 Other disorders of ear, not elsewhere classified	0.000	0.998	0.002
C24.9 Biliary tract, unspecified	0.001	0.998	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.998	0.002
M75.2 Bicipital tendinitis	0.002	0.998	0.000
H93.1 Tinnitus	0.000	0.998	0.002
C17.0 Duodenum	0.001	0.998	0.000
C21.8 Overlapping lesion of rectum, anus and anal canal	0.001	0.998	0.000
M75.8 Other shoulder lesions	0.001	0.998	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.000	0.998	0.002
Z45.0 Adjustment and management of cardiac pacemaker	0.002	0.998	0.000
C22.9 Liver, unspecified	0.001	0.998	0.000
H93.3 Disorders of acoustic nerve	0.000	0.998	0.001
I27.0 Primary pulmonary hypertension	0.000	0.998	0.002
C17.8 Overlapping lesion of small intestine	0.001	0.998	0.000
C17.3 Meckel's diverticulum	0.001	0.998	0.000
C17.1 Jejunum	0.001	0.998	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.998	0.001
C25 Malignant neoplasm of pancreas	0.001	0.998	0.000
C17.9 Small intestine, unspecified	0.001	0.998	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.998	0.001
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.998	0.001
E16.4 Abnormal secretion of gastrin	0.000	0.998	0.001
E16.3 Increased secretion of glucagon	0.000	0.998	0.001
A41.9 Septicaemia, unspecified	0.002	0.998	0.000
H93.9 Disorder of ear, unspecified	0.000	0.998	0.001
M75.3 Calcific tendinitis of shoulder	0.001	0.998	0.000
C16 Malignant neoplasm of stomach	0.001	0.998	0.000
M75.9 Shoulder lesion, unspecified	0.001	0.998	0.000
S00.8 Superficial injury of other parts of head	0.002	0.998	0.000
T42.4 Benzodiazepines	0.000	0.998	0.001
C17.2 Ileum	0.001	0.998	0.000
N87.0 Mild cervical dysplasia	0.000	0.998	0.001
M85.65 Other cyst of bone (Pelvic region and thigh)	0.000	0.998	0.001
C22.7 Other specified carcinomas of liver	0.001	0.998	0.000
C22.4 Other sarcomas of liver	0.001	0.998	0.000
C22.3 Angiosarcoma of liver	0.001	0.998	0.000
C22.2 Hepatoblastoma	0.001	0.998	0.000
H93.2 Other abnormal auditory perceptions	0.000	0.998	0.001
M19.02 Primary arthrosis of other joints (Upper arm)	0.000	0.999	0.001
M19.00 Primary arthrosis of other joints (Multiple sites)	0.000	0.999	0.001
H93.0 Degenerative and vascular disorders of ear	0.000	0.999	0.001
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.000	0.999	0.001
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.000	0.999	0.001
M19.03 Primary arthrosis of other joints (Forearm)	0.000	0.999	0.001
G56.2 Lesion of ulnar nerve	0.000	0.999	0.001
M75.81 Other shoulder lesions, right shoulder	0.001	0.999	0.000
C25.1 Body of pancreas	0.001	0.999	0.000
E11.5 With peripheral circulatory complications	0.000	0.999	0.001
K75.8 Other specified inflammatory liver diseases	0.000	0.999	0.001
M19.0 Primary arthrosis of other joints	0.000	0.999	0.001
C16.6 Greater curvature of stomach, unspecified	0.001	0.999	0.000
C22.1 Intrahepatic bile duct carcinoma	0.001	0.999	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.000	0.999	0.001
C15 Malignant neoplasm of oesophagus	0.001	0.999	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.001	0.999	0.000
S62.30 Fracture of other metacarpal bone (closed)	0.000	0.999	0.001
C16.8 Overlapping lesion of stomach	0.001	0.999	0.000
C16.3 Pyloric antrum	0.001	0.999	0.000
M85.6 Other cyst of bone	0.000	0.999	0.001
T42.0 Hydantoin derivatives	0.000	0.999	0.001
C25.8 Overlapping lesion of pancreas	0.001	0.999	0.000
C25.4 Endocrine pancreas	0.001	0.999	0.000
C25.2 Tail of pancreas	0.001	0.999	0.000
N64.5 Other signs and symptoms in breast	0.001	0.999	0.000
C16.9 Stomach, unspecified	0.001	0.999	0.000
C25.3 Pancreatic duct	0.001	0.999	0.000
H52.2 Astigmatism	0.001	0.999	0.000
H52.0 Hypermetropia	0.001	0.999	0.000
O80 Single spontaneous delivery	0.001	0.999	0.000
M85.67 Other cyst of bone (Ankle and foot)	0.000	0.999	0.001
C16.5 Lesser curvature of stomach, unspecified	0.001	0.999	0.000
C16.2 Body of stomach	0.001	0.999	0.000
C25.7 Other parts of pancreas	0.001	0.999	0.000
O80.8 Other single spontaneous delivery	0.001	0.999	0.000
T40.2 Other opioids	0.000	0.999	0.001
T42.3 Barbiturates	0.000	0.999	0.001
T50.6 Antidotes and chelating agents, not elsewhere classified	0.000	0.999	0.001
H90-H95 Other disorders of ear	0.000	0.999	0.001
M19.04 Primary arthrosis of other joints (Hand)	0.000	0.999	0.001
C16.1 Fundus of stomach	0.001	0.999	0.000
C25.0 Head of pancreas	0.001	0.999	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.000	0.999	0.001
T42.5 Mixed antiepileptics, not elsewhere classified	0.000	0.999	0.001
T42.2 Succinimides and oxazolidinediones	0.000	0.999	0.001
M85.68 Other cyst of bone (Other)	0.000	0.999	0.001
C22.0 Liver cell carcinoma	0.001	0.999	0.000
H52.3 Anisometropia and aniseikonia	0.001	0.999	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.000	0.999	0.001
J47 Bronchiectasis	0.000	0.999	0.001
M19.08 Primary arthrosis of other joints (Other)	0.000	0.999	0.001
M19.05 Primary arthrosis of other joints (Pelvic region and thigh)	0.000	0.999	0.001
S82.80 Fractures of other parts of lower leg (closed)	0.000	0.999	0.001
C15.1 Thoracic part of oesophagus	0.001	0.999	0.000
C15.0 Cervical part of oesophagus	0.001	0.999	0.000
C16.4 Pylorus	0.001	0.999	0.000
K75.4 Autoimmune hepatitis	0.000	0.999	0.001
T50.8 Diagnostic agents	0.000	0.999	0.001
T50.7 Analeptics and opioid receptor antagonists	0.000	0.999	0.001
T50.5 Appetite depressants	0.000	0.999	0.001
T50.4 Drugs affecting uric acid metabolism	0.000	0.999	0.001
T50.3 Electrolytic, caloric and water-balance agents	0.000	0.999	0.001
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.000	0.999	0.001
T50.0 Mineralocorticoids and their antagonists	0.000	0.999	0.001
N60-N64 Disorders of breast	0.001	0.999	0.000
M85.69 Other cyst of bone (Site unspecified)	0.000	0.999	0.001
M85.63 Other cyst of bone (Forearm)	0.000	0.999	0.001
M85.62 Other cyst of bone (Upper arm)	0.000	0.999	0.001
M85.61 Other cyst of bone (Shoulder region)	0.000	0.999	0.001
M85.60 Other cyst of bone (Multiple sites)	0.000	0.999	0.001
C15.8 Overlapping lesion of oesophagus	0.001	0.999	0.000
C15.2 Abdominal part of oesophagus	0.001	0.999	0.000
C25.9 Pancreas, unspecified	0.001	0.999	0.000
T50.1 Loop [high-ceiling] diuretics	0.000	0.999	0.001
Z08.0 Follow-up examination after surgery for malignant neoplasm	0.001	0.999	0.000
H52 Disorders of refraction and accommodation	0.001	0.999	0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.000	0.999	0.001
N64 Other disorders of breast	0.001	0.999	0.000
M85.64 Other cyst of bone (Hand)	0.000	0.999	0.001
C15.4 Middle third of oesophagus	0.001	0.999	0.000
H52.1 Myopia	0.001	0.999	0.000
H95.0 Recurrent cholesteatoma of postmastoidectomy cavity	0.000	0.999	0.001
S00.0 Superficial injury of scalp	0.001	0.999	0.000
N62 Hypertrophy of breast	0.001	0.999	0.000
M19.06 Primary arthrosis of other joints-Lower leg	0.000	0.999	0.001
M85.66 Other cyst of bone (Lower leg)	0.000	0.999	0.001
E06.3 Autoimmune thyroiditis	0.000	0.999	0.001
M85.9 Disorder of bone density and structure, unspecified	0.000	0.999	0.001
N64.9 Disorder of breast, unspecified	0.001	0.999	0.000
O80.1 Spontaneous breech delivery	0.001	0.999	0.000
O80.0 Spontaneous vertex delivery	0.001	0.999	0.000
T42.1 Iminostilbenes	0.000	0.999	0.001
M85 Other disorders of bone density and structure	0.000	0.999	0.001
M19.09 Primary arthrosis of other joints (Site unspecified)	0.000	0.999	0.001
C15.3 Upper third of oesophagus	0.001	0.999	0.000
H52.7 Disorder of refraction, unspecified	0.001	0.999	0.000
H94 Other disorders of ear in diseases classified elsewhere	0.000	0.999	0.001
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.000	0.999	0.001
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.000	0.999	0.001
M85.98 Disorder of bone density and structure, unspecified (Other)	0.000	0.999	0.001
H52.4 Presbyopia	0.001	0.999	0.000
J86.9 Pyothorax without fistula	0.000	0.999	0.001
T40.6 Other and unspecified narcotics	0.000	0.999	0.001
N61 Inflammatory disorders of breast	0.001	0.999	0.000
T36 Poisoning by systemic antibiotics	0.000	0.999	0.001
T36-T50 Poisoning by drugs, medicaments and biological substances	0.000	0.999	0.001
H52.6 Other disorders of refraction	0.001	0.999	0.000
H52.5 Disorders of accommodation	0.001	0.999	0.000
N64.3 Galactorrhoea not associated with childbirth	0.001	0.999	0.000
N64.2 Atrophy of breast	0.001	0.999	0.000
T36.4 Tetracyclines	0.000	0.999	0.001
Z01.8 Other specified special examinations	0.000	0.999	0.001
M85.99 Disorder of bone density and structure, unspecified (Site unspecified)	0.000	0.999	0.001
H91.1 Presbycusis	0.000	0.999	0.001
N64.0 Fissure and fistula of nipple	0.001	0.999	0.000
T36.0 Penicillins	0.000	0.999	0.001
Y83.4 Other reconstructive surgery	0.001	0.999	0.000
C19 Malignant neoplasm of rectosigmoid junction	0.001	0.999	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.000	0.999	0.001
M19.07 Primary arthrosis of other joints (Ankle and foot)	0.000	0.999	0.001
M85.97 Disorder of bone density and structure, unspecified (Ankle and foot)	0.000	0.999	0.001
M85.96 Disorder of bone density and structure, unspecified (Lower leg)	0.000	0.999	0.001
M85.95 Disorder of bone density and structure, unspecified (Pelvic region and thigh)	0.000	0.999	0.001
M85.94 Disorder of bone density and structure, unspecified (Hand)	0.000	0.999	0.001
M85.93 Disorder of bone density and structure, unspecified (Forearm)	0.000	0.999	0.001
M85.92 Disorder of bone density and structure, unspecified (Upper arm)	0.000	0.999	0.001
M85.91 Disorder of bone density and structure, unspecified (Shoulder region)	0.000	0.999	0.001
M85.90 Disorder of bone density and structure, unspecified (Multiple sites)	0.000	0.999	0.001
C16.0 Cardia	0.001	0.999	0.000
H95.9 Postprocedural disorder of ear and mastoid process, unspecified	0.000	0.999	0.001
H95.8 Other postprocedural disorders of ear and mastoid process	0.000	0.999	0.001
H95.1 Other disorders following mastoidectomy	0.000	0.999	0.001
M85.5 Aneurysmal bone cyst	0.000	0.999	0.001
M85.4 Solitary bone cyst	0.000	0.999	0.001
M85.3 Osteitis condensans	0.000	0.999	0.001
M85.1 Skeletal fluorosis	0.000	0.999	0.001
T36.8 Other systemic antibiotics	0.000	0.999	0.001
T40.3 Methadone	0.000	0.999	0.001
T43.5 Other and unspecified antipsychotics and neuroleptics	0.000	0.999	0.001
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.999	0.001
A41.0 Septicaemia due to Staphylococcus aureus	0.000	0.999	0.001
H61.0 Perichondritis of external ear	0.001	0.999	0.000
H94.8 Other specified disorders of ear in diseases classified elsewhere	0.000	0.999	0.001
H94.0 Acoustic neuritis in infectious and parasitic diseases classified elsewhere	0.000	0.999	0.001
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene	0.001	0.999	0.000
M85.2 Hyperostosis of skull	0.000	0.999	0.001
M85.0 Fibrous dysplasia (monostotic)	0.000	0.999	0.001
T37.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.999	0.001
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.000	0.999	0.001
T40.8 Lysergide [LSD]	0.000	0.999	0.001
T40.7 Cannabis (derivatives)	0.000	0.999	0.001
T40.0 Opium	0.000	0.999	0.001
T43.8 Other psychotropic drugs, not elsewhere classified	0.000	0.999	0.001
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.000	0.999	0.001
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.000	0.999	0.001
H91.8 Other specified hearing loss	0.000	0.999	0.001
H91.3 Deaf mutism, not elsewhere classified	0.000	0.999	0.001
M80.9 Unspecified osteoporosis with pathological fracture	0.001	0.999	0.000
T36.9 Systemic antibiotic, unspecified	0.000	0.999	0.001
T36.7 Antifungal antibiotics, systemically used	0.000	0.999	0.001
T36.6 Rifamycins	0.000	0.999	0.001
T36.5 Aminoglycosides	0.000	0.999	0.001
T36.2 Chloramphenicol group	0.000	0.999	0.001
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.000	0.999	0.001
T37.2 Antimalarials and drugs acting on other blood protozoa	0.000	0.999	0.001
T38.1 Thyroid hormones and substitutes	0.000	0.999	0.001
T40.1 Heroin	0.000	0.999	0.001
T43.9 Psychotropic drug, unspecified	0.000	0.999	0.001
T43.2 Other and unspecified antidepressants	0.000	0.999	0.001
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.999	0.001
T41 Poisoning by anaesthetics and therapeutic gases	0.000	0.999	0.001
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.999	0.001
M85.47 Solitary bone cyst (Ankle and foot)	0.000	0.999	0.001
M85.45 Solitary bone cyst (Pelvic region and thigh)	0.000	0.999	0.001
N64.1 Fat necrosis of breast	0.001	0.999	0.000
S00.1 Contusion of eyelid and periocular area	0.001	0.999	0.000
T36.3 Macrolides	0.000	0.999	0.001
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.000	0.999	0.001
T37.5 Antiviral drugs	0.000	0.999	0.001
T37.4 Anthelminthics	0.000	0.999	0.001
T37.3 Other antiprotozoal drugs	0.000	0.999	0.001
T37.1 Antimycobacterial drugs	0.000	0.999	0.001
T37.0 Sulphonamides	0.000	0.999	0.001
T39.0 Salicylates	0.000	0.999	0.001
T40.5 Cocaine	0.000	0.999	0.001
T43.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.999	0.001
Y44.6 Natural blood and blood products	0.000	0.999	0.001
K75 Other inflammatory liver diseases	0.000	0.999	0.001
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.000	0.999	0.001
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.000	0.999	0.001
M85.19 Skeletal fluorosis (Site unspecified)	0.000	0.999	0.001
M85.18 Skeletal fluorosis (Other)	0.000	0.999	0.001
M85.17 Skeletal fluorosis (Ankle and foot)	0.000	0.999	0.001
M85.16 Skeletal fluorosis (Lower leg)	0.000	0.999	0.001
M85.15 Skeletal fluorosis (Pelvic region and thigh)	0.000	0.999	0.001
M85.14 Skeletal fluorosis (Hand)	0.000	0.999	0.001
M85.13 Skeletal fluorosis (Forearm)	0.000	0.999	0.001
M85.12 Skeletal fluorosis (Upper arm)	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations