TreeWAS – Variant ID: rs983561

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E05.9 Thyrotoxicosis, unspecified	1.000	0.000	0.000
E10.9 Without complications	1.000	0.000	0.000
K90.0 Coeliac disease	1.000	0.000	0.000
E05 Thyrotoxicosis [hyperthyroidism]	1.000	0.000	0.000
E10 Insulin-dependent diabetes mellitus	1.000	0.000	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	1.000	0.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000	0.000
E05.0 Thyrotoxicosis with diffuse goitre	1.000	0.000	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	1.000	0.000	0.000
E10-E14 Diabetes mellitus	1.000	0.000	0.000
C44 Other malignant neoplasms of skin	1.000	0.000	0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type	1.000	0.000	0.000
E00-E07 Disorders of thyroid gland	1.000	0.000	0.000
C83 Diffuse non-Hodgkin's lymphoma	1.000	0.000	0.000
C83.3 Large cell (diffuse)	1.000	0.000	0.000
E10.1 With ketoacidosis	1.000	0.000	0.000
E10.3 With ophthalmic complications	0.999	0.001	0.000
H00.1 Chalazion	0.000	0.001	0.999
C44.2 Skin of ear and external auricular canal	0.997	0.003	0.000
C44.3 Skin of other and unspecified parts of face	0.997	0.003	0.000
C43-C44 Melanoma and other malignant neoplasms of skin	0.996	0.004	0.000
K52.8 Other specified non-infective gastro-enteritis and colitis	0.996	0.004	0.000
Chapter II Neoplasms	0.995	0.005	0.000
K90 Intestinal malabsorption	0.995	0.005	0.000
C44.6 Skin of upper limb, including shoulder	0.995	0.005	0.000
# Top node	0.993	0.007	0.000
E10.2 With renal complications	0.991	0.009	0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.991	0.009	0.000
K50-K52 Noninfective enteritis and colitis	0.988	0.012	0.000
K52 Other non-infective gastro-enteritis and colitis	0.988	0.012	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.987	0.013	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.985	0.015	0.000
Chapter XI Diseases of the digestive system	0.984	0.016	0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.984	0.016	0.000
K90-K93 Other diseases of the digestive system	0.984	0.016	0.000
E14 Unspecified diabetes mellitus	0.980	0.020	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.979	0.021	0.000
L40-L45 Papulosquamous disorders	0.975	0.022	0.002
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.975	0.025	0.000
L43 Lichen planus	0.975	0.025	0.001
L43.9 Lichen planus, unspecified	0.973	0.027	0.000
C85.1 B-cell lymphoma, unspecified	0.969	0.031	0.000
C02 Malignant neoplasm of other and unspecified parts of tongue	0.969	0.031	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.967	0.033	0.000
M18 Arthrosis of first carpometacarpal joint	0.967	0.033	0.000
E10.4 With neurological complications	0.967	0.033	0.000
M35.0 Sicca syndrome [Sjogren]	0.964	0.036	0.000
M15-M19 Arthrosis	0.964	0.036	0.000
M20-M25 Other joint disorders	0.963	0.037	0.000
M35 Other systemic involvement of connective tissue	0.962	0.038	0.000
K51 Ulcerative colitis	0.960	0.040	0.000
E16 Other disorders of pancreatic internal secretion	0.958	0.042	0.000
C44.4 Skin of scalp and neck	0.955	0.045	0.000
M34 Systemic sclerosis	0.953	0.047	0.000
L40.9 Psoriasis, unspecified	0.000	0.050	0.950
E14.3 With ophthalmic complications	0.945	0.055	0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral	0.945	0.055	0.000
E16.2 Hypoglycaemia, unspecified	0.945	0.055	0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.943	0.057	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.936	0.064	0.000
K51.4 Pseudopolyposis of colon	0.934	0.066	0.000
K51.0 Ulcerative (chronic) enterocolitis	0.931	0.069	0.000
L50-L54 Urticaria and erythema	0.926	0.074	0.000
D69 Purpura and other haemorrhagic conditions	0.926	0.074	0.000
K90.9 Intestinal malabsorption, unspecified	0.925	0.075	0.000
M18.1 Other primary arthrosis of first carpometacarpal joint	0.924	0.076	0.000
C81 Hodgkin's disease	0.922	0.078	0.000
D60-D64 Aplastic and other anaemias	0.918	0.082	0.000
C02.9 Tongue, unspecified	0.915	0.085	0.000
D80-D89 Certain disorders involving the immune mechanism	0.914	0.086	0.000
M24 Other specific joint derangements	0.909	0.091	0.000
L10-L14 Bullous disorders	0.897	0.103	0.000
C84 Peripheral and cutaneous T-cell lymphomas	0.893	0.107	0.000
C02.1 Border of tongue	0.892	0.108	0.000
M34.9 Systemic sclerosis, unspecified	0.891	0.109	0.000
H00 Hordeolum and chalazion	0.000	0.127	0.873
M24.1 Other articular cartilage disorders	0.873	0.127	0.000
C06 Malignant neoplasm of other and unspecified parts of mouth	0.872	0.128	0.000
E40-E46 Malnutrition	0.862	0.138	0.000
M60-M63 Disorders of muscles	0.860	0.140	0.000
M34.1 CR(E)ST syndrome	0.856	0.144	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.847	0.153	0.000
H00.0 Hordeolum and other deep inflammation of eyelid	0.000	0.153	0.847
C81.1 Nodular sclerosis	0.844	0.156	0.000
L52 Erythema nodosum	0.842	0.158	0.000
M32 Systemic lupus erythematosus	0.841	0.159	0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.838	0.162	0.000
D69.4 Other primary thrombocytopenia	0.838	0.162	0.000
D61 Other aplastic anaemias	0.836	0.164	0.000
L13 Other bullous disorders	0.835	0.165	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.834	0.166	0.000
M15 Polyarthrosis	0.833	0.167	0.000
D69.6 Thrombocytopenia, unspecified	0.830	0.170	0.000
E06 Thyroiditis	0.830	0.170	0.000
D55-D59 Haemolytic anaemias	0.822	0.178	0.000
E14.8 With unspecified complications	0.822	0.178	0.000
M34.8 Other forms of systemic sclerosis	0.821	0.179	0.000
E10.0 With coma	0.819	0.181	0.000
J45.9 Asthma, unspecified	0.000	0.185	0.815
C88 Malignant immunoproliferative diseases	0.814	0.186	0.000
K51.9 Ulcerative colitis, unspecified	0.812	0.188	0.000
L53 Other erythematous conditions	0.811	0.189	0.000
L51 Erythema multiforme	0.810	0.190	0.000
E07 Other disorders of thyroid	0.807	0.193	0.000
C02.3 Anterior two-thirds of tongue, part unspecified	0.806	0.194	0.000
M24.5 Contracture of joint	0.806	0.194	0.000
D69.2 Other nonthrombocytopenic purpura	0.802	0.198	0.000
D80 Immunodeficiency with predominantly antibody defects	0.801	0.199	0.000
M35.7 Hypermobility syndrome	0.801	0.199	0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.800	0.200	0.000
C84.5 Other and unspecified T-cell lymphomas	0.799	0.201	0.000
E10.8 With unspecified complications	0.798	0.202	0.000
C40-C41 Malignant neoplasms of bone and articular cartilage	0.798	0.202	0.000
C04 Malignant neoplasm of floor of mouth	0.797	0.203	0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.793	0.207	0.000
C83.1 Small cleaved cell (diffuse)	0.793	0.207	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.791	0.209	0.000
L13.0 Dermatitis herpetiformis	0.791	0.209	0.000
E14.1 With ketoacidosis	0.790	0.210	0.000
L43.0 Hypertrophic lichen planus	0.789	0.210	0.000
M24.11 Other articular cartilage disorders (Shoulder region)	0.789	0.211	0.000
D83 Common variable immunodeficiency	0.788	0.212	0.000
M60 Myositis	0.784	0.216	0.000
C85.7 Other specified types of non-Hodgkin's lymphoma	0.779	0.221	0.000
C91 Lymphoid leukaemia	0.776	0.224	0.000
C03 Malignant neoplasm of gum	0.775	0.225	0.000
D69.5 Secondary thrombocytopenia	0.773	0.227	0.000
M34.0 Progressive systemic sclerosis	0.773	0.227	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.768	0.232	0.000
C83.7 Burkitt's tumour	0.768	0.232	0.000
E10.7 With multiple complications	0.768	0.232	0.000
C10 Malignant neoplasm of oropharynx	0.766	0.234	0.000
L43.8 Other lichen planus	0.765	0.235	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.765	0.235	0.000
E46 Unspecified protein-energy malnutrition	0.763	0.237	0.000
C82.2 Large cell, follicular	0.759	0.240	0.000
C05 Malignant neoplasm of palate	0.759	0.241	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.756	0.244	0.000
C83.0 Small cell (diffuse)	0.755	0.244	0.000
D62 Acute posthaemorrhagic anaemia	0.755	0.245	0.000
C82.4 Follicular lymphoma grade IIIb	0.755	0.245	0.000
M32.1 Systemic lupus erythematosus with organ or system involvement	0.754	0.246	0.000
C44.0 Skin of lip	0.754	0.246	0.000
E10.5 With peripheral circulatory complications	0.753	0.247	0.000
D73 Diseases of spleen	0.752	0.248	0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.751	0.248	0.000
C08 Malignant neoplasm of other and unspecified major salivary glands	0.751	0.249	0.000
C07 Malignant neoplasm of parotid gland	0.749	0.251	0.000
C06.0 Cheek mucosa	0.747	0.253	0.000
E14.2 Withrenal complications	0.745	0.255	0.000
E07.8 Other specified disorders of thyroid	0.745	0.255	0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.743	0.257	0.000
C44.9 Malignant neoplasm of skin, unspecified	0.743	0.257	0.000
E14.5 With peripheral circulatory complications	0.740	0.260	0.000
D61.9 Aplastic anaemia, unspecified	0.731	0.269	0.000
C81.9 Hodgkin's disease, unspecified	0.730	0.270	0.000
C82.0 Small cleaved cell, follicular	0.729	0.271	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.726	0.274	0.000
C44.7 Skin of lower limb, including hip	0.724	0.276	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.722	0.278	0.000
C82.3 Follicular lymphoma grade IIIa	0.721	0.279	0.000
L40 Psoriasis	0.344	0.279	0.377
E14.6 With other specified complications	0.721	0.279	0.000
M35.1 Other overlap syndromes	0.720	0.280	0.000
C85.0 Lymphosarcoma	0.717	0.283	0.000
E05.5 Thyroid crisis or storm	0.717	0.283	0.000
E05.4 Thyrotoxicosis factitia	0.717	0.283	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.717	0.283	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.717	0.283	0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.717	0.283	0.000
C94 Other leukaemias of specified cell type	0.717	0.283	0.000
E12 Malnutrition-related diabetes mellitus	0.717	0.283	0.000
C44.8 Overlapping lesion of skin	0.717	0.283	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.717	0.283	0.000
E00 Congenital iodine-deficiency syndrome	0.717	0.283	0.000
C83.6 Undifferentiated (diffuse)	0.717	0.283	0.000
C83.5 Lymphoblastic (diffuse)	0.717	0.283	0.000
C83.4 Immunoblastic (diffuse)	0.717	0.283	0.000
C83.2 Mixed small and large cell (diffuse)	0.717	0.283	0.000
E14.4 With neurological complications	0.716	0.284	0.000
L51.9 Erythema multiforme, unspecified	0.714	0.286	0.000
M15.4 Erosive (osteo)arthrosis	0.713	0.287	0.000
K90.3 Pancreatic steatorrhoea	0.713	0.287	0.000
K90.2 Blind loop syndrome, not elsewhere classified	0.713	0.287	0.000
K90.1 Tropical sprue	0.713	0.287	0.000
M40-M43 Deforming dorsopathies	0.712	0.287	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.712	0.288	0.000
K50 Crohn's disease [regional enteritis]	0.711	0.288	0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.711	0.289	0.000
C82.6 Cutaneous follicle centre lymphoma	0.710	0.290	0.000
C82.5 Diffuse follicle centre lymphoma	0.710	0.290	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.710	0.290	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.707	0.293	0.000
D73.0 Hyposplenism	0.707	0.293	0.000
K93 Disorders of other digestive organs in diseases classified elsewhere	0.705	0.295	0.000
M24.56 Contracture of joint (Lower leg)	0.704	0.296	0.000
K52.3 Indeterminate colitis	0.704	0.296	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.703	0.297	0.000
K51.1 Ulcerative (chronic) ileocolitis	0.703	0.297	0.000
C02.2 Ventral surface of tongue	0.702	0.297	0.000
E14.7 With multiple complications	0.702	0.298	0.000
E14.0 With coma	0.702	0.298	0.000
L44 Other papulosquamous disorders	0.699	0.299	0.002
L41 Parapsoriasis	0.699	0.299	0.002
L45 Papulosquamous disorders in diseases classified elsewhere	0.699	0.299	0.002
C06.9 Mouth, unspecified	0.700	0.300	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.700	0.300	0.000
D61.1 Drug-induced aplastic anaemia	0.699	0.301	0.000
E15 Nondiabetic hypoglycaemic coma	0.699	0.301	0.000
L43.3 Subacute (active) lichen planus	0.699	0.301	0.001
L43.2 Lichenoid drug reaction	0.699	0.301	0.001
L43.1 Bullous lichen planus	0.699	0.301	0.001
K90.8 Other intestinal malabsorption	0.699	0.301	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.699	0.301	0.000
K51.5 Mucosal proctocolitis	0.699	0.301	0.000
C13 Malignant neoplasm of hypopharynx	0.698	0.302	0.000
D83.9 Common variable immunodeficiency, unspecified	0.698	0.302	0.000
K50.1 Crohn's disease of large intestine	0.697	0.303	0.000
D56 Thalassaemia	0.696	0.304	0.000
D64 Other anaemias	0.695	0.305	0.000
L53.9 Erythematous condition, unspecified	0.695	0.305	0.000
C02.8 Overlapping lesion of tongue	0.694	0.305	0.000
C02.0 Dorsal surface of tongue	0.694	0.305	0.000
M18.5 Other secondary arthrosis of first carpometacarpal joint	0.693	0.306	0.000
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral	0.693	0.306	0.000
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint	0.693	0.306	0.000
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral	0.693	0.306	0.000
L12 Pemphigoid	0.692	0.308	0.000
M60.9 Myositis, unspecified	0.692	0.308	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.690	0.310	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.690	0.310	0.000
M35.5 Multifocal fibrosclerosis	0.690	0.310	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.690	0.310	0.000
E20-E35 Disorders of other endocrine glands	0.690	0.310	0.000
C84.8 Cutaneous T-cell lymphoma, unspecified	0.688	0.312	0.000
C81.2 Mixed cellularity	0.687	0.313	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.687	0.313	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.687	0.313	0.000
E16.4 Abnormal secretion of gastrin	0.687	0.313	0.000
E16.3 Increased secretion of glucagon	0.687	0.313	0.000
M24.9 Joint derangement, unspecified	0.686	0.314	0.000
M35.2 Behcet's disease	0.684	0.315	0.000
C91.5 Adult T-cell leukaemia	0.684	0.316	0.000
M34.2 Systemic sclerosis induced by drugs and chemicals	0.683	0.317	0.000
D84 Other immunodeficiencies	0.680	0.320	0.000
E50-E64 Other nutritional deficiencies	0.680	0.320	0.000
L57 Skin changes due to chronic exposure to nonionising radiation	0.678	0.322	0.000
D73.5 Infarction of spleen	0.676	0.324	0.000
C12 Malignant neoplasm of pyriform sinus	0.676	0.324	0.000
M00-M03 Infectious arthropathies	0.676	0.324	0.000
E06.3 Autoimmune thyroiditis	0.675	0.325	0.000
K52.1 Toxic gastro-enteritis and colitis	0.674	0.326	0.000
M24.7 Protrusio acetabuli	0.673	0.327	0.000
M24.17 Other articular cartilage disorders (Ankle and foot)	0.671	0.329	0.000
D67 Hereditary factor IX deficiency	0.671	0.329	0.000
C91.9 Lymphoid leukaemia, unspecified	0.669	0.331	0.000
M15.0 Primary generalised (osteo)arthrosis	0.669	0.331	0.000
C84.0 Mycosis fungoides	0.668	0.332	0.000
D58 Other hereditary haemolytic anaemias	0.665	0.335	0.000
L54 Erythema in diseases classified elsewhere	0.664	0.336	0.000
C86 Other specified types of T/NK-cell lymphoma	0.664	0.336	0.000
D69.8 Other specified haemorrhagic conditions	0.664	0.336	0.000
D69.1 Qualitative platelet defects	0.664	0.336	0.000
Q43 Other congenital malformations of intestine	0.663	0.337	0.000
Q60-Q64 Congenital malformations of the urinary system	0.663	0.337	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.663	0.337	0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx	0.662	0.338	0.000
C81.7 Other Hodgkin's disease	0.661	0.339	0.000
C81.4 Lymphocyte-rich classical Hodgkin lymphoma	0.661	0.339	0.000
C81.3 Lymphocytic depletion	0.661	0.339	0.000
E10.6 With other specified complications	0.658	0.342	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.658	0.342	0.000
C41 Malignant neoplasm of bone and articular cartilage of other and unspecified sites	0.657	0.342	0.000
M15.2 Bouchard's nodes (with arthropathy)	0.657	0.343	0.000
C00 Malignant neoplasm of lip	0.657	0.343	0.000
D81 Combined immunodeficiencies	0.655	0.344	0.000
M60.0 Infective myositis	0.654	0.346	0.000
L53.0 Toxic erythema	0.652	0.348	0.000
D89.1 Cryoglobulinaemia	0.651	0.349	0.000
C95 Leukaemia of unspecified cell type	0.650	0.350	0.000
C74 Malignant neoplasm of adrenal gland	0.649	0.351	0.000
E06.9 Thyroiditis, unspecified	0.644	0.356	0.000
L10 Pemphigus	0.643	0.357	0.000
L14 Bullous disorders in diseases classified elsewhere	0.643	0.357	0.000
C81.0 Lymphocytic predominance	0.643	0.357	0.000
M24.51 Contracture of joint (Shoulder region)	0.642	0.358	0.000
E28 Ovarian dysfunction	0.642	0.358	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.641	0.359	0.000
M24.6 Ankylosis of joint	0.641	0.359	0.000
C04.0 Anterior floor of mouth	0.640	0.360	0.000
C06.2 Retromolar area	0.640	0.360	0.000
C84.9 Mature T/NK-cell lymphoma, unspecified	0.640	0.360	0.000
C84.7 Anaplastic large cell lymphoma, ALK-negative	0.640	0.360	0.000
C84.6 Anaplastic large cell lymphoma, ALK-positive	0.640	0.360	0.000
C84.3 Lymphoepithelioid lymphoma	0.640	0.360	0.000
C84.2 T-zone lymphoma	0.640	0.360	0.000
C84.1 Sezary's diease	0.640	0.360	0.000
C11 Malignant neoplasm of nasopharynx	0.639	0.361	0.000
C88.0 Waldenstrom's macroglobulinaemia	0.639	0.361	0.000
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]	0.638	0.362	0.000
M24.57 Contracture of joint (Ankle and foot)	0.638	0.362	0.000
D82 Immunodeficiency associated with other major defects	0.636	0.363	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.636	0.364	0.000
L42 Pityriasis rosea	0.634	0.364	0.002
M24.2 Disorder of ligament	0.636	0.364	0.000
C05.0 Hard palate	0.633	0.367	0.000
M65-M68 Disorders of synovium and tendon	0.633	0.367	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.632	0.368	0.000
M24.19 Other articular cartilage disorders (Site unspecified)	0.626	0.374	0.000
M24.18 Other articular cartilage disorders (Other)	0.626	0.374	0.000
M24.14 Other articular cartilage disorders (Hand)	0.626	0.374	0.000
M24.12 Other articular cartilage disorders (Upper arm)	0.626	0.374	0.000
M24.10 Other articular cartilage disorders (Multiple sites)	0.626	0.374	0.000
C93 Monocytic leukaemia	0.625	0.374	0.000
C03.1 Lower gum	0.625	0.375	0.000
C06.8 Overlapping lesion of other and unspecified parts of mouth	0.625	0.375	0.000
C06.1 Vestibule of mouth	0.625	0.375	0.000
D63 Anaemia in chronic diseases classified elsewhere	0.624	0.375	0.000
M30 Polyarteritis nodosa and related conditions	0.623	0.376	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.619	0.381	0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.618	0.381	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.618	0.382	0.000
E45 Retarded development following protein-energy malnutrition	0.618	0.382	0.000
E43 Unspecified severe protein-energy malnutrition	0.618	0.382	0.000
E42 Marasmic kwashiorkor	0.618	0.382	0.000
E41 Nutritional marasmus	0.618	0.382	0.000
E40 Kwashiorkor	0.618	0.382	0.000
D56.1 Beta thalassaemia	0.618	0.382	0.000
M63 Disorders of muscle in diseases classified elsewhere	0.617	0.383	0.000
M61 Calcification and ossification of muscle	0.617	0.383	0.000
M62 Other disorders of muscle	0.615	0.385	0.000
M60.99 Myositis, unspecified (Site unspecified)	0.613	0.386	0.000
M40 Kyphosis and lordosis	0.612	0.388	0.000
C10.9 Oropharynx, unspecified	0.609	0.391	0.000
L51.1 Bullous erythema multiforme	0.609	0.391	0.000
Q35-Q37 Cleft lip and cleft palate	0.608	0.392	0.000
D61.0 Constitutional aplastic anaemia	0.607	0.393	0.000
K52.2 Allergic and dietetic gastro-enteritis and colitis	0.606	0.394	0.000
C69 Malignant neoplasm of eye and adnexa	0.604	0.396	0.000
C04.9 Floor of mouth, unspecified	0.604	0.396	0.000
M35.8 Other specified systemic involvement of connective tissue	0.604	0.396	0.000
L57.0 Actinic keratosis	0.604	0.396	0.000
M32.9 Systemic lupus erythematosus, unspecified	0.603	0.397	0.000
M32.8 Other forms of systemic lupus erythematosus	0.603	0.397	0.000
M32.0 Drug-induced systemic lupus erythematosus	0.603	0.397	0.000
C84.4 Peripheral T-cell lymphoma	0.603	0.397	0.000
M15.3 Secondary multiple arthrosis	0.602	0.398	0.000
Q43.9 Congenital malformation of intestine, unspecified	0.602	0.398	0.000
E16.1 Other hypoglycaemia	0.601	0.399	0.000
C21.1 Anal canal	0.001	0.399	0.600
D61.8 Other specified aplastic anaemias	0.599	0.400	0.000
D61.3 Idiopathic aplastic anaemia	0.599	0.400	0.000
D61.2 Aplastic anaemia due to other external agents	0.599	0.400	0.000
L13.9 Bullous disorder, unspecified	0.599	0.401	0.000
L13.8 Other specified bullous disorders	0.599	0.401	0.000
L13.1 Subcorneal pustular dermatitis	0.599	0.401	0.000
D89.3 Immune reconstitution syndrome	0.598	0.402	0.000
M86-M90 Other osteopathies	0.596	0.404	0.000
C21 Malignant neoplasm of anus and anal canal	0.009	0.404	0.587
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.595	0.404	0.000
E06.5 Other chronic thyroiditis	0.595	0.405	0.000
E06.4 Drug-induced thyroiditis	0.595	0.405	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.595	0.405	0.000
E06.1 Subacute thyroiditis	0.595	0.405	0.000
E06.0 Acute thyroiditis	0.595	0.405	0.000
L11 Other acantholytic disorders	0.594	0.405	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.594	0.406	0.000
L56 Other acute skin changes due to ultraviolet radiation	0.594	0.406	0.000
Q61 Cystic kidney disease	0.593	0.407	0.000
C02.4 Lingual tonsil	0.592	0.408	0.000
C01 Malignant neoplasm of base of tongue	0.591	0.409	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.590	0.410	0.000
D57 Sickle-cell disorders	0.589	0.411	0.000
D55 Anaemia due to enzyme disorders	0.589	0.411	0.000
C21.0 Anus, unspecified	0.001	0.413	0.586
C88.9 Malignant immunoproliferative disease, unspecified	0.583	0.416	0.000
C88.7 Other malignant immunoproliferative diseases	0.583	0.416	0.000
C88.3 Immunoproliferative small intestinal disease	0.583	0.416	0.000
C88.2 Gamma heavy chain disease	0.583	0.416	0.000
C88.1 Alpha heavy chain disease	0.583	0.416	0.000
E28.3 Primary ovarian failure	0.583	0.417	0.000
L53.3 Other chronic figurate erythema	0.581	0.419	0.000
L53.2 Erythema marginatum	0.581	0.419	0.000
L53.1 Erythema annulare centrifugum	0.581	0.419	0.000
L51.8 Other erythema multiforme	0.581	0.419	0.000
L51.2 Toxic epidermal necrolysis [Lyell]	0.581	0.419	0.000
L51.0 Nonbullous erythema multiforme	0.581	0.419	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.579	0.420	0.000
E07.1 Dyshormogenetic goitre	0.579	0.421	0.000
E07.0 Hypersecretion of calcitonin	0.579	0.421	0.000
C08.0 Submandibular gland	0.578	0.422	0.000
M24.59 Contracture of joint (Site unspecified)	0.578	0.422	0.000
M24.58 Contracture of joint (Other)	0.578	0.422	0.000
M24.53 Contracture of joint (Forearm)	0.578	0.422	0.000
M24.52 Contracture of joint (Upper arm)	0.578	0.422	0.000
M24.50 Contracture of joint (Multiple sites)	0.578	0.422	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.574	0.426	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.574	0.426	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.574	0.426	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.574	0.426	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.574	0.426	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.574	0.426	0.000
D73.1 Hypersplenism	0.574	0.426	0.000
L53.8 Other specified erythematous conditions	0.574	0.426	0.000
L58 Radiodermatitis	0.573	0.426	0.000
L55 Sunburn	0.573	0.426	0.000
E23 Hypofunction and other disorders of pituitary gland	0.573	0.427	0.000
C42 hematopoietic and reticuloendothelial systems (ICD-O-3 specific)	0.572	0.428	0.000
C04.8 Overlapping lesion of floor of mouth	0.572	0.428	0.000
C04.1 Lateral floor of mouth	0.572	0.428	0.000
E26 Hyperaldosteronism	0.571	0.429	0.000
M15.1 Heberden's nodes (with arthropathy)	0.571	0.429	0.000
C40 Malignant neoplasm of bone and articular cartilage of limbs	0.569	0.430	0.000
C73 Malignant neoplasm of thyroid gland	0.569	0.431	0.000
M15.8 Other polyarthrosis	0.568	0.432	0.000
D74 Methaemoglobinaemia	0.567	0.433	0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.567	0.433	0.000
D71 Functional disorders of polymorphonuclear neutrophils	0.567	0.433	0.000
Q50-Q56 Congenital malformations of genital organs	0.566	0.434	0.000
D73.4 Cyst of spleen	0.566	0.434	0.000
C75 Malignant neoplasm of other endocrine glands and related structures	0.566	0.434	0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.565	0.434	0.000
D83.8 Other common variable immunodeficiencies	0.565	0.435	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.565	0.435	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.565	0.435	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.565	0.435	0.000
Q00-Q07 Congenital malformations of the nervous system	0.565	0.435	0.000
M24.13 Other articular cartilage disorders (Forearm)	0.563	0.437	0.000
M60.8 Other myositis	0.562	0.438	0.000
M60.2 Foreign body granuloma of soft tissue, not elsewhere classified	0.562	0.438	0.000
M60.1 Interstitial myositis	0.562	0.438	0.000
M24.26 Disorder of ligament (Lower leg)	0.559	0.441	0.000
C82.1 Mixed small cleaved and large cell, follicular	0.557	0.443	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.556	0.444	0.000
C91.8 Mature B-cell leukaemia Burkitt-type	0.556	0.444	0.000
C91.7 Other lymphoid leukaemia	0.556	0.444	0.000
C91.6 Prolymphocytic leukaemia of T-cell type	0.556	0.444	0.000
C91.3 Prolymphocytic leukaemia	0.556	0.444	0.000
C91.2 Subacute lymphocytic leukaemia	0.556	0.444	0.000
C03.9 Gum, unspecified	0.556	0.444	0.000
C03.0 Upper gum	0.556	0.444	0.000
M80-M85 Disorders of bone density and structure	0.556	0.444	0.000
L57.8 Other skin changes due to chronic exposure to nonionising radiation	0.554	0.446	0.000
C91.0 Acute lymphoblastic leukaemia	0.553	0.447	0.000
M24.54 Contracture of joint (Hand)	0.552	0.448	0.000
E13 Other specified diabetes mellitus	0.552	0.448	0.000
D64.3 Other sideroblastic anaemias	0.552	0.448	0.000
D64.0 Hereditary sideroblastic anaemia	0.552	0.448	0.000
M15.00 Primary generalized (osteo)arthrosis, Multiple sites	0.551	0.449	0.000
Q43.0 Meckel's diverticulum	0.550	0.450	0.000
C10.8 Overlapping lesion of oropharynx	0.549	0.451	0.000
C10.4 Branchial cleft	0.549	0.451	0.000
C10.3 Posterior wall of oropharynx	0.549	0.451	0.000
C10.2 Lateral wall of oropharynx	0.549	0.451	0.000
C10.1 Anterior surface of epiglottis	0.549	0.451	0.000
C10.0 Vallecula	0.549	0.451	0.000
M17 Gonarthrosis [arthrosis of knee]	0.549	0.451	0.000
C08.9 Major salivary gland, unspecified	0.545	0.454	0.000
C05.8 Overlapping lesion of palate	0.544	0.456	0.000
C05.2 Uvula	0.544	0.456	0.000
M15.9 Polyarthrosis, unspecified	0.543	0.457	0.000
D84.9 Immunodeficiency, unspecified	0.542	0.457	0.000
E05.8 Other thyrotoxicosis	0.542	0.457	0.000
E25 Adrenogenital disorders	0.542	0.458	0.000
E51 Thiamine deficiency	0.540	0.460	0.000
M60.05 Infective myositis (Pelvic region and thigh)	0.540	0.460	0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.539	0.460	0.000
D73.2 Chronic congestive splenomegaly	0.539	0.461	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.539	0.461	0.000
C08.8 Overlapping lesion of major salivary glands	0.539	0.461	0.000
C08.1 Sublingual gland	0.539	0.461	0.000
C05.9 Palate, unspecified	0.536	0.463	0.000
L59 Other disorders of skin and subcutaneous tissue related to radiation	0.536	0.464	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.535	0.465	0.000
E28.2 Polycystic ovarian syndrome	0.535	0.465	0.000
L12.1 Cicatricial pemphigoid	0.535	0.465	0.000
D73.9 Disease of spleen, unspecified	0.535	0.465	0.000
D70 Agranulocytosis	0.535	0.465	0.000
Q43.1 Hirschsprung's disease	0.533	0.467	0.000
M40.2 Other and unspecified kyphosis	0.533	0.467	0.000
C97 Malignant neoplasms of independent (primary) multiple sites	0.533	0.467	0.000
D69.0 Allergic purpura	0.532	0.468	0.000
Q61.3 Polycystic kidney, unspecified	0.530	0.470	0.000
C70 Malignant neoplasm of meninges	0.530	0.470	0.000
M24.55 Contracture of joint (Pelvic region and thigh)	0.529	0.471	0.000
Q40 Other congenital malformations of upper alimentary tract	0.529	0.471	0.000
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere	0.528	0.472	0.000
M24.66 Ankylosis of joint (Lower leg)	0.527	0.472	0.000
C41.2 Vertebral column	0.527	0.473	0.000
M24.96 Joint derangement, unspecified (Lower leg)	0.526	0.474	0.000
M60.95 Myositis, unspecified (Pelvic region and thigh)	0.526	0.474	0.000
Q43.3 Congenital malformations of intestinal fixation	0.525	0.475	0.000
D58.0 Hereditary spherocytosis	0.525	0.475	0.000
C13.0 Postcricoid region	0.524	0.476	0.000
D64.8 Other specified anaemias	0.524	0.476	0.000
C90 Multiple myeloma and malignant plasma cell neoplasms	0.523	0.477	0.000
Q61.9 Cystic kidney disease, unspecified	0.521	0.479	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.520	0.480	0.000
M17.1 Other primary gonarthrosis	0.520	0.480	0.000
L12.9 Pemphigoid, unspecified	0.519	0.481	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations