TreeWAS – Variant ID: rs9847987

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K60.2 Anal fissure, unspecified	0.067	0.933	0.000
I51.8 Other ill-defined heart diseases	0.046	0.954	0.000
C91.1 Chronic lymphocytic leukaemia	0.000	0.962	0.038
K60 Fissure and fistula of anal and rectal regions	0.035	0.965	0.000
K60.1 Chronic anal fissure	0.031	0.969	0.000
K60.0 Acute anal fissure	0.026	0.974	0.000
K60.3 Anal fistula	0.025	0.975	0.000
K60.5 Anorectal fistula	0.025	0.975	0.000
K05.3 Chronic periodontitis	0.000	0.976	0.024
C91 Lymphoid leukaemia	0.000	0.977	0.023
K60.4 Rectal fistula	0.020	0.979	0.000
C91.9 Lymphoid leukaemia, unspecified	0.000	0.981	0.019
C91.0 Acute lymphoblastic leukaemia	0.000	0.982	0.018
C91.8 Mature B-cell leukaemia Burkitt-type	0.000	0.984	0.016
C91.7 Other lymphoid leukaemia	0.000	0.984	0.016
C91.6 Prolymphocytic leukaemia of T-cell type	0.000	0.984	0.016
C91.3 Prolymphocytic leukaemia	0.000	0.984	0.016
C91.2 Subacute lymphocytic leukaemia	0.000	0.984	0.016
C91.5 Adult T-cell leukaemia	0.000	0.984	0.016
C91.4 Hairy-cell leukaemia	0.000	0.984	0.016
D86 Sarcoidosis	0.014	0.986	0.000
K05 Gingivitis and periodontal diseases	0.000	0.986	0.014
D86.9 Sarcoidosis, unspecified	0.014	0.986	0.000
D86.1 Sarcoidosis of lymph nodes	0.013	0.987	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.012	0.988	0.000
D80-D89 Certain disorders involving the immune mechanism	0.012	0.988	0.000
K05.6 Periodontal disease, unspecified	0.000	0.988	0.012
K05.1 Chronic gingivitis	0.000	0.988	0.012
D86.0 Sarcoidosis of lung	0.011	0.989	0.000
D86.8 Sarcoidosis of other and combined sites	0.011	0.989	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.011	0.989	0.000
N89.8 Other specified noninflammatory disorders of vagina	0.000	0.989	0.011
D84 Other immunodeficiencies	0.011	0.989	0.000
S72.00 Fracture of neck of femur (closed)	0.011	0.989	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.011	0.989	0.000
D86.3 Sarcoidosis of skin	0.011	0.989	0.000
K05.2 Acute periodontitis	0.000	0.990	0.010
K05.4 Periodontosis	0.000	0.990	0.010
K05.0 Acute gingivitis	0.000	0.990	0.010
D83 Common variable immunodeficiency	0.010	0.990	0.000
M48.06 Spinal stenosis (Lumbar region)	0.010	0.990	0.000
K05.5 Other periodontal diseases	0.000	0.990	0.009
D84.1 Defects in the complement system	0.009	0.991	0.000
D84.9 Immunodeficiency, unspecified	0.009	0.991	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.009	0.991	0.000
N89.5 Stricture and atresia of vagina	0.000	0.991	0.009
D82 Immunodeficiency associated with other major defects	0.009	0.991	0.000
D81 Combined immunodeficiencies	0.009	0.991	0.000
D80 Immunodeficiency with predominantly antibody defects	0.009	0.991	0.000
D83.9 Common variable immunodeficiency, unspecified	0.009	0.991	0.000
N89 Other noninflammatory disorders of vagina	0.000	0.991	0.009
D89.1 Cryoglobulinaemia	0.009	0.991	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.009	0.991	0.000
S72.0 Fracture of neck of femur	0.008	0.992	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.008	0.992	0.000
D84.8 Other specified immunodeficiencies	0.008	0.992	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.008	0.992	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.008	0.992	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.008	0.992	0.000
D89.3 Immune reconstitution syndrome	0.008	0.992	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.008	0.992	0.000
K05.22 Aggressive periodontitis, generalized	0.000	0.992	0.007
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.007	0.992	0.000
D83.8 Other common variable immunodeficiencies	0.007	0.992	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.007	0.992	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.007	0.992	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.007	0.992	0.000
S72.10 Pertrochanteric fracture (closed)	0.007	0.993	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.007	0.993	0.000
S61.1 Open wound of finger(s) with damage to nail	0.007	0.993	0.000
N89.6 Tight hymenal ring	0.000	0.993	0.007
M48.0 Spinal stenosis	0.007	0.993	0.000
R63.8 Other symptoms and signs concerning food and fluid intake	0.000	0.993	0.007
S72.1 Pertrochanteric fracture	0.007	0.993	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.007	0.993	0.000
D81.9 Combined immunodeficiency, unspecified	0.006	0.993	0.000
D81.8 Other combined immunodeficiencies	0.006	0.993	0.000
D81.7 Major histocompatibility complex class II deficiency	0.006	0.993	0.000
D81.6 Major histocompatibility complex class I deficiency	0.006	0.993	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.006	0.993	0.000
D81.4 Nezelof's syndrome	0.006	0.993	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.006	0.993	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.006	0.993	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.006	0.993	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.006	0.993	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.006	0.993	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.006	0.993	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.006	0.993	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.006	0.993	0.000
D82.2 Immunodeficiency with short-limbed stature	0.006	0.993	0.000
D82.1 Di George's syndrome	0.006	0.993	0.000
D82.0 Wiskott-Aldrich syndrome	0.006	0.993	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.006	0.993	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.006	0.993	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.006	0.993	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.006	0.993	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.006	0.993	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.006	0.993	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.006	0.993	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.006	0.993	0.000
S72 Fracture of femur	0.007	0.993	0.000
N89.7 Haematocolpos	0.000	0.993	0.006
N89.4 Leukoplakia of vagina	0.000	0.993	0.006
N89.3 Dysplasia of vagina, unspecified	0.000	0.993	0.006
N89.2 Severe vaginal dysplasia, not elsewhere classified	0.000	0.993	0.006
N89.1 Moderate vaginal dysplasia	0.000	0.993	0.006
N89.0 Mild vaginal dysplasia	0.000	0.993	0.006
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.006	0.993	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.006	0.993	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.006	0.993	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.006	0.993	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.006	0.993	0.000
M48.00 Spinal stenosis (Multiple sites in spine)	0.007	0.993	0.000
N89.9 Noninflammatory disorder of vagina, unspecified	0.000	0.993	0.006
B37.8 Candidiasis of other sites	0.006	0.994	0.000
M48.07 Spinal stenosis (Lumbosacral region)	0.006	0.994	0.000
S72.01 Fracture of neck of femur (open)	0.006	0.994	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.006	0.994	0.000
S72.9 Fracture of femur, part unspecified	0.006	0.994	0.000
Q24 Other congenital malformations of heart	0.006	0.994	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.006	0.994	0.000
Q24.8 Other specified congenital malformations of heart	0.005	0.994	0.000
S72.90 Fracture of femur, part unspecified (closed)	0.005	0.995	0.000
Q21 Congenital malformations of cardiac septa	0.005	0.995	0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)	0.005	0.995	0.000
Q21.0 Ventricular septal defect	0.005	0.995	0.000
M48.05 Spinal stenosis (Thoracolumbar region)	0.005	0.995	0.000
M48.03 Spinal stenosis (Cervicothoracic region)	0.005	0.995	0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)	0.005	0.995	0.000
S72.11 Pertrochanteric fracture (open)	0.005	0.995	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.005	0.995	0.000
S72.7 Multiple fractures of femur	0.005	0.995	0.000
Q24.9 Congenital malformation of the heart, unspecified	0.005	0.995	0.000
Z75.1 Person awaiting admission to adequate facility elsewhere	0.000	0.995	0.005
S72.8 Fractures of other parts of femur	0.005	0.995	0.000
S72.3 Fracture of shaft of femur	0.005	0.995	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.005	0.995	0.000
Q23 Congenital malformations of aortic and mitral valves	0.005	0.995	0.000
Q25 Congenital malformations of great arteries	0.004	0.995	0.000
S72.91 Fracture of femur, part unspecified (open)	0.004	0.995	0.000
M48.09 Spinal stenosis (Site unspecified)	0.004	0.996	0.000
Q24.5 Malformation of coronary vessels	0.004	0.996	0.000
M48.04 Spinal stenosis (Thoracic region)	0.004	0.996	0.000
Q24.6 Congenital heart block	0.004	0.996	0.000
Q24.4 Congenital subaortic stenosis	0.004	0.996	0.000
Q24.3 Pulmonary infundibular stenosis	0.004	0.996	0.000
Q24.2 Cor triatriatum	0.004	0.996	0.000
Q24.1 Levocardia	0.004	0.996	0.000
Q24.0 Dextrocardia	0.004	0.996	0.000
S72.4 Fracture of lower end of femur	0.004	0.996	0.000
Q26 Congenital malformations of great veins	0.004	0.996	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.004	0.996	0.000
Q21.1 Atrial septal defect	0.004	0.996	0.000
R22.1 Localised swelling, mass and lump, neck	0.004	0.996	0.000
Q21.9 Congenital malformation of cardiac septum, unspecified	0.004	0.996	0.000
Q21.8 Other congenital malformations of cardiac septa	0.004	0.996	0.000
Q21.4 Aortopulmonary septal defect	0.004	0.996	0.000
Q21.3 Tetralogy of Fallot	0.004	0.996	0.000
Q21.2 Atrioventricular septal defect	0.004	0.996	0.000
Q22.5 Ebstein's anomaly	0.004	0.996	0.000
Q28 Other congenital malformations of circulatory system	0.004	0.996	0.000
Z90.1 Acquired absence of breast(s)	0.004	0.996	0.000
S72.2 Subtrochanteric fracture	0.004	0.996	0.000
Q27 Other congenital malformations of peripheral vascular system	0.004	0.996	0.000
M05 Seropositive rheumatoid arthritis	0.004	0.996	0.000
S72.71 Multiple fractures of femur (open)	0.004	0.996	0.000
S72.70 Multiple fractures of femur (closed)	0.004	0.996	0.000
Q23.0 Congenital stenosis of aortic valve	0.004	0.996	0.000
Q25.4 Other congenital malformations of aorta	0.004	0.996	0.000
S72.31 Fracture of shaft of femur (open)	0.003	0.996	0.000
S72.81 Fractures of other parts of femur (open)	0.003	0.996	0.000
Q23.1 Congenital insufficiency of aortic valve	0.004	0.996	0.000
R40.0 Somnolence	0.000	0.996	0.004
I51 Complications and ill-defined descriptions of heart disease	0.004	0.996	0.000
Q22.9 Congenital malformation of tricuspid valve, unspecified	0.003	0.996	0.000
Q22.8 Other congenital malformations of tricuspid valve	0.003	0.996	0.000
Q22.6 Hypoplastic right heart syndrome	0.003	0.996	0.000
Q22.4 Congenital tricuspid stenosis	0.003	0.996	0.000
Q22.3 Other congenital malformations of pulmonary valve	0.003	0.996	0.000
Q22.2 Congenital pulmonary valve insufficiency	0.003	0.996	0.000
Q22.1 Congenital pulmonary valve stenosis	0.003	0.996	0.000
Q22.0 Pulmonary valve atresia	0.003	0.996	0.000
Q38.7 Pharyngeal pouch	0.004	0.996	0.000
Q25.1 Coarctation of aorta	0.003	0.996	0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.003	0.996	0.000
Q23.8 Other congenital malformations of aortic and mitral valves	0.003	0.996	0.000
Q23.4 Hypoplastic left heart syndrome	0.003	0.996	0.000
Q23.3 Congenital mitral insufficiency	0.003	0.996	0.000
Q23.2 Congenital mitral stenosis	0.003	0.996	0.000
Q25.9 Congenital malformation of great arteries, unspecified	0.003	0.996	0.000
Q25.8 Other congenital malformations of great arteries	0.003	0.996	0.000
Q25.7 Other congenital malformations of pulmonary artery	0.003	0.996	0.000
Q25.6 Stenosis of pulmonary artery	0.003	0.996	0.000
Q25.5 Atresia of pulmonary artery	0.003	0.996	0.000
Q25.3 Stenosis of aorta	0.003	0.996	0.000
Q25.2 Atresia of aorta	0.003	0.996	0.000
Q25.0 Patent ductus arteriosus	0.003	0.996	0.000
M48 Other spondylopathies	0.004	0.996	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.004	0.996	0.000
M48.02 Spinal stenosis (Cervical region)	0.003	0.996	0.000
I51.6 Cardiovascular disease, unspecified	0.003	0.996	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.003	0.996	0.000
Q51.3 Bicornate uterus	0.003	0.997	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.003	0.997	0.000
S72.80 Fractures of other parts of femur (closed)	0.003	0.997	0.000
S70-S79 Injuries to the hip and thigh	0.003	0.997	0.000
S72.30 Fracture of shaft of femur (closed)	0.003	0.997	0.000
Q27.3 Peripheral arteriovenous malformation	0.003	0.997	0.000
Q28.3 Other malformations of cerebral vessels	0.003	0.997	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.003	0.997	0.000
S72.41 Fracture of lower end of femur (open)	0.003	0.997	0.000
Q20.9 Congenital malformation of cardiac chambers and connexions, unspecified	0.003	0.997	0.000
Q20.8 Other congenital malformations of cardiac chambers and connexions	0.003	0.997	0.000
Q20.6 Isomerism of atrial appendages	0.003	0.997	0.000
Q20.5 Discordant atrioventricular connexion	0.003	0.997	0.000
Q20.4 Double inlet ventricle	0.003	0.997	0.000
Q20.3 Discordant ventriculoarterial connexion	0.003	0.997	0.000
Q20.2 Double outlet left ventricle	0.003	0.997	0.000
Q20.1 Double outlet right ventricle	0.003	0.997	0.000
Q20.0 Common arterial trunk	0.003	0.997	0.000
Q26.9 Congenital malformation of great vein, unspecified	0.003	0.997	0.000
Q26.8 Other congenital malformations of great veins	0.003	0.997	0.000
Q26.6 Portal vein-hepatic artery fistula	0.003	0.997	0.000
Q26.5 Anomalous portal venous connexion	0.003	0.997	0.000
Q26.4 Anomalous pulmonary venous connexion, unspecified	0.003	0.997	0.000
Q26.3 Partial anomalous pulmonary venous connexion	0.003	0.997	0.000
Q26.2 Total anomalous pulmonary venous connexion	0.003	0.997	0.000
Q26.1 Persistent left superior vena cava	0.003	0.997	0.000
Q26.0 Congenital stenosis of vena cava	0.003	0.997	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.003	0.997	0.000
Q51 Congenital malformations of uterus and cervix	0.003	0.997	0.000
Q28.9 Congenital malformation of circulatory system, unspecified	0.003	0.997	0.000
Q28.8 Other specified congenital malformations of circulatory system	0.003	0.997	0.000
Q28.1 Other malformations of precerebral vessels	0.003	0.997	0.000
Q28.0 Arteriovenous malformation of precerebral vessels	0.003	0.997	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.003	0.997	0.000
S72.21 Subtrochanteric fracture (open)	0.003	0.997	0.000
Q40 Other congenital malformations of upper alimentary tract	0.003	0.997	0.000
Q27.4 Congenital phlebectasia	0.003	0.997	0.000
Q27.2 Other congenital malformations of renal artery	0.003	0.997	0.000
Q27.1 Congenital renal artery stenosis	0.003	0.997	0.000
Q27.0 Congenital absence and hypoplasia of umbilical artery	0.003	0.997	0.000
S79 Other and unspecified injuries of hip and thigh	0.003	0.997	0.000
M13.00 Polyarthritis, unspecified (Multiple sites)	0.000	0.997	0.003
I51.0 Cardiac septal defect, acquired	0.003	0.997	0.000
Q50-Q56 Congenital malformations of genital organs	0.003	0.997	0.000
M05.8 Other seropositive rheumatoid arthritis	0.003	0.997	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.003	0.997	0.000
M05.2 Rheumatoid vasculitis	0.003	0.997	0.000
M05.1 Rheumatoid lung disease	0.003	0.997	0.000
M05.0 Felty's syndrome	0.003	0.997	0.000
M48.56 Collapsed vertebra, not elsewhere classified (Lumbar region)	0.003	0.997	0.000
Q30 Congenital malformations of nose	0.003	0.997	0.000
M48.5 Collapsed vertebra, not elsewhere classified	0.003	0.997	0.000
S79.9 Unspecified injury of hip and thigh	0.003	0.997	0.000
S70 Superficial injury of hip and thigh	0.003	0.997	0.000
Q30.3 Congenital perforated nasal septum	0.003	0.997	0.000
Q51.2 Other doubling of uterus	0.003	0.997	0.000
I51.5 Myocardial degeneration	0.003	0.997	0.000
I51.2 Rupture of papillary muscle, not elsewhere classified	0.003	0.997	0.000
Q14 Congenital malformations of posterior segment of eye	0.003	0.997	0.000
Q90 Down's syndrome	0.003	0.997	0.000
Q35-Q37 Cleft lip and cleft palate	0.003	0.997	0.000
Q99 Other chromosome abnormalities, not elsewhere classified	0.003	0.997	0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.003	0.997	0.000
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.003	0.997	0.000
Q28.2 Arteriovenous malformation of cerebral vessels	0.003	0.997	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.003	0.997	0.000
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit	0.003	0.997	0.000
M48.9 Spondylopathy, unspecified	0.003	0.997	0.000
M48.8 Other specified spondylopathies	0.003	0.997	0.000
M48.4 Fatigue fracture of vertebra	0.003	0.997	0.000
M48.3 Traumatic spondylopathy	0.003	0.997	0.000
M48.2 Kissing spine	0.003	0.997	0.000
M48.1 Ankylosing hyperostosis [Forestier]	0.003	0.997	0.000
Q40.8 Other specified congenital malformations of upper alimentary tract	0.003	0.997	0.000
K52.8 Other specified non-infective gastro-enteritis and colitis	0.000	0.997	0.003
Q00-Q07 Congenital malformations of the nervous system	0.003	0.997	0.000
Q27.8 Other specified congenital malformations of peripheral vascular system	0.003	0.997	0.000
Q38.8 Other congenital malformations of pharynx	0.003	0.997	0.000
Q38.6 Other congenital malformations of mouth	0.003	0.997	0.000
Q38.5 Congenital malformations of palate, not elsewhere classified	0.003	0.997	0.000
Q38.4 Congenital malformations of salivary glands and ducts	0.003	0.997	0.000
Q38.3 Other congenital malformations of tongue	0.003	0.997	0.000
Q38.2 Macroglossia	0.003	0.997	0.000
Q38.1 Ankyloglossia	0.003	0.997	0.000
Q38.0 Congenital malformations of lips, not elsewhere classified	0.003	0.997	0.000
S70.0 Contusion of hip	0.003	0.997	0.000
Q45 Other congenital malformations of digestive system	0.003	0.997	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.003	0.997	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.003	0.997	0.000
Q40.2 Other specified congenital malformations of stomach	0.003	0.997	0.000
Q44.4 Choledochal cyst	0.003	0.997	0.000
S78 Traumatic amputation of hip and thigh	0.003	0.997	0.000
S77 Crushing injury of hip and thigh	0.003	0.997	0.000
S75 Injury of blood vessels at hip and thigh level	0.003	0.997	0.000
S74 Injury of nerves at hip and thigh level	0.003	0.997	0.000
S71 Open wound of hip and thigh	0.003	0.997	0.000
I51.3 Intracardiac thrombosis, not elsewhere classified	0.003	0.997	0.000
Q17 Other congenital malformations of ear	0.003	0.997	0.000
Q14.1 Congenital malformation of retina	0.003	0.997	0.000
S70.8 Other superficial injuries of hip and thigh	0.003	0.997	0.000
Q18 Other congenital malformations of face and neck	0.003	0.997	0.000
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified	0.003	0.997	0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified	0.003	0.997	0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified	0.003	0.997	0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified	0.003	0.997	0.000
Q91 Edwards' syndrome and Patau's syndrome	0.003	0.997	0.000
Q53 Undescended testicle	0.003	0.997	0.000
Q90.9 Down's syndrome, unspecified	0.002	0.997	0.000
Q16 Congenital malformations of ear causing impairment of hearing	0.002	0.997	0.000
Q15 Other congenital malformations of eye	0.002	0.997	0.000
Q13 Congenital malformations of anterior segment of eye	0.002	0.997	0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos	0.002	0.997	0.000
Q51.9 Congenital malformation of uterus and cervix, unspecified	0.002	0.997	0.000
Q51.7 Congenital fistulae between uterus and digestive and urinary tracts	0.002	0.997	0.000
Q51.6 Embryonic cyst of cervix	0.002	0.997	0.000
Q51.5 Agenesis and aplasia of cervix	0.002	0.997	0.000
Q51.4 Unicornate uterus	0.002	0.997	0.000
Q51.1 Doubling of uterus with doubling of cervix and vagina	0.002	0.997	0.000
Q51.0 Agenesis and aplasia of uterus	0.002	0.997	0.000
Q43 Other congenital malformations of intestine	0.003	0.997	0.000
Q96 Turner's syndrome	0.002	0.997	0.000
I07.1 Tricuspid insufficiency	0.003	0.997	0.000
Q99.8 Other specified chromosome abnormalities	0.002	0.997	0.000
Q34 Other congenital malformations of respiratory system	0.002	0.997	0.000
Q33 Congenital malformations of lung	0.002	0.997	0.000
Q32 Congenital malformations of trachea and bronchus	0.002	0.997	0.000
Q31 Congenital malformations of larynx	0.002	0.997	0.000
Q98.4 Klinefelter's syndrome, unspecified	0.002	0.997	0.000
S42.10 Fracture of scapula (closed)	0.003	0.997	0.000
Q40.9 Congenital malformation of upper alimentary tract, unspecified	0.002	0.997	0.000
Q40.3 Congenital malformation of stomach, unspecified	0.002	0.997	0.000
Q40.1 Congenital hiatus hernia	0.002	0.997	0.000
Q40.0 Congenital hypertrophic pyloric stenosis	0.002	0.997	0.000
Q12 Congenital lens malformations	0.002	0.997	0.000
Q10.0 Congenital ptosis	0.002	0.997	0.000
S72.40 Fracture of lower end of femur (closed)	0.002	0.997	0.000
S79.7 Multiple injuries of hip and thigh	0.002	0.997	0.000
Q56 Indeterminate sex and pseudohermaphroditism	0.002	0.997	0.000
Q55 Other congenital malformations of male genital organs	0.002	0.997	0.000
Q52 Other congenital malformations of female genitalia	0.002	0.997	0.000
M05.09 Felty's syndrome (Site unspecified)	0.002	0.997	0.000
M05.08 Felty's syndrome (Other)	0.002	0.997	0.000
M05.07 Felty's syndrome (Ankle and foot)	0.002	0.997	0.000
M05.06 Felty's syndrome (Lower leg)	0.002	0.997	0.000
M05.05 Felty's syndrome (Pelvic region and thigh)	0.002	0.997	0.000
M05.04 Felty's syndrome (Hand)	0.002	0.997	0.000
M05.03 Felty's syndrome (Forearm)	0.002	0.997	0.000
M05.02 Felty's syndrome (Upper arm)	0.002	0.997	0.000
M05.01 Felty's syndrome (Shoulder region)	0.002	0.997	0.000
M05.00 Felty's syndrome (Multiple sites)	0.002	0.997	0.000
M05.19 Rheumatoid lung disease (Site unspecified)	0.002	0.997	0.000
M05.18 Rheumatoid lung disease (Other)	0.002	0.997	0.000
M05.17 Rheumatoid lung disease (Ankle and foot)	0.002	0.997	0.000
M05.16 Rheumatoid lung disease (Lower leg)	0.002	0.997	0.000
M05.15 Rheumatoid lung disease (Pelvic region and thigh)	0.002	0.997	0.000
M05.14 Rheumatoid lung disease (Hand)	0.002	0.997	0.000
M05.13 Rheumatoid lung disease (Forearm)	0.002	0.997	0.000
M05.12 Rheumatoid lung disease (Upper arm)	0.002	0.997	0.000
M05.11 Rheumatoid lung disease (Shoulder region)	0.002	0.997	0.000
M05.10 Rheumatoid lung disease (Multiple sites)	0.002	0.997	0.000
M05.29 Rheumatoid vasculitis (Site unspecified)	0.002	0.997	0.000
M05.28 Rheumatoid vasculitis (Other)	0.002	0.997	0.000
M05.27 Rheumatoid vasculitis (Ankle and foot)	0.002	0.997	0.000
M05.26 Rheumatoid vasculitis (Lower leg)	0.002	0.997	0.000
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)	0.002	0.997	0.000
M05.24 Rheumatoid vasculitis (Hand)	0.002	0.997	0.000
M05.23 Rheumatoid vasculitis (Forearm)	0.002	0.997	0.000
M05.22 Rheumatoid vasculitis (Upper arm)	0.002	0.997	0.000
M05.21 Rheumatoid vasculitis (Shoulder region)	0.002	0.997	0.000
M05.20 Rheumatoid vasculitis (Multiple sites)	0.002	0.997	0.000
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)	0.002	0.997	0.000
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)	0.002	0.997	0.000
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)	0.002	0.997	0.000
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)	0.002	0.997	0.000
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)	0.002	0.997	0.000
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)	0.002	0.997	0.000
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)	0.002	0.997	0.000
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)	0.002	0.997	0.000
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)	0.002	0.997	0.000
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)	0.002	0.997	0.000
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)	0.002	0.997	0.000
M05.88 Other seropositive rheumatoid arthritis (Other)	0.002	0.997	0.000
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)	0.002	0.997	0.000
M05.86 Other seropositive rheumatoid arthritis (Lower leg)	0.002	0.997	0.000
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)	0.002	0.997	0.000
M05.84 Other seropositive rheumatoid arthritis (Hand)	0.002	0.997	0.000
M05.83 Other seropositive rheumatoid arthritis (Forearm)	0.002	0.997	0.000
M05.82 Other seropositive rheumatoid arthritis (Upper arm)	0.002	0.997	0.000
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)	0.002	0.997	0.000
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)	0.002	0.997	0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.002	0.997	0.000
S79.8 Other specified injuries of hip and thigh	0.002	0.998	0.000
Q30.9 Congenital malformation of nose, unspecified	0.002	0.998	0.000
Q30.8 Other congenital malformations of nose	0.002	0.998	0.000
Q30.2 Fissured, notched and cleft nose	0.002	0.998	0.000
Q30.1 Agenesis and underdevelopment of nose	0.002	0.998	0.000
Q30.0 Choanal atresia	0.002	0.998	0.000
Q37 Cleft palate with cleft lip	0.002	0.998	0.000
S76 Injury of muscle and tendon at hip and thigh level	0.002	0.998	0.000
M48.59 Collapsed vertebra, not elsewhere classified (Site unspecified)	0.002	0.998	0.000
M48.58 Collapsed vertebra, not elsewhere classified (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M48.57 Collapsed vertebra, not elsewhere classified (Lumbosacral region)	0.002	0.998	0.000
M48.53 Collapsed vertebra, not elsewhere classified (Cervicothoracic region)	0.002	0.998	0.000
M48.52 Collapsed vertebra, not elsewhere classified (Cervical region)	0.002	0.998	0.000
M48.51 Collapsed vertebra, not elsewhere classified (Occipito-atlanto-axial region)	0.002	0.998	0.000
I51.4 Myocarditis, unspecified	0.002	0.998	0.000
S70.7 Multiple superficial injuries of hip and thigh	0.002	0.998	0.000
S70.1 Contusion of thigh	0.002	0.998	0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.002	0.998	0.000
I44.1 Atrioventricular block, second degree	0.002	0.998	0.000
Q18.0 Sinus, fistula and cyst of branchial cleft	0.002	0.998	0.000
Q90.2 Trisomy 21, translocation	0.002	0.998	0.000
Q90.1 Trisomy 21, mosaicism (mitotic nondisjunction)	0.002	0.998	0.000
Q90.0 Trisomy 21, meiotic nondisjunction	0.002	0.998	0.000
Z75.2 Other waiting period for investigation and treatment	0.000	0.998	0.002
Q14.9 Congenital malformation of posterior segment of eye, unspecified	0.002	0.998	0.000
Q14.8 Other congenital malformations of posterior segment of eye	0.002	0.998	0.000
Q14.3 Congenital malformation of choroid	0.002	0.998	0.000
Q14.2 Congenital malformation of optic disk	0.002	0.998	0.000
Q14.0 Congenital malformation of vitreous humour	0.002	0.998	0.000
Q99.9 Chromosomal abnormality, unspecified	0.002	0.998	0.000
Q99.2 Fragile X chromosome	0.002	0.998	0.000
Q99.1 46,XX true hermaphrodite	0.002	0.998	0.000
Q99.0 Chimera 46,XX/46,XY	0.002	0.998	0.000
Z53.9 Procedure not carried out, unspecified reason	0.002	0.998	0.000
Q36 Cleft lip	0.002	0.998	0.000
Q35 Cleft palate	0.002	0.998	0.000
Q43.3 Congenital malformations of intestinal fixation	0.002	0.998	0.000
Q98.9 Sex chromosome abnormality, male phenotype, unspecified	0.002	0.998	0.000
Q98.8 Other specified sex chromosome abnormalities, male phenotype	0.002	0.998	0.000
Q98.7 Male with sex chromosome mosaicism	0.002	0.998	0.000
Q98.6 Male with structurally abnormal sex chromosome	0.002	0.998	0.000
Q98.5 Karyotype 47,XYY	0.002	0.998	0.000
Q98.3 Other male with 46,XX karyotype	0.002	0.998	0.000
Q98.2 Klinefelter's syndrome, male with 46,XX karyotype	0.002	0.998	0.000
Q98.1 Klinefelter's syndrome, male with more than two X chromosomes	0.002	0.998	0.000
Q98.0 Klinefelter's syndrome karyotype 47,XXY	0.002	0.998	0.000
Z75 Problems related to medical facilities and other health care	0.000	0.998	0.002
M48.55 Collapsed vertebra, not elsewhere classified (Thoracolumbar region)	0.002	0.998	0.000
Q44.7 Other congenital malformations of liver	0.002	0.998	0.000
Q44.5 Other congenital malformations of bile ducts	0.002	0.998	0.000
Q44.3 Congenital stenosis and stricture of bile ducts	0.002	0.998	0.000
Q44.2 Atresia of bile ducts	0.002	0.998	0.000
Q44.1 Other congenital malformations of gallbladder	0.002	0.998	0.000
Q44.0 Agenesis, aplasia and hypoplasia of gallbladder	0.002	0.998	0.000
Q53.1 Undescended testicle, unilateral	0.002	0.998	0.000
Q05 Spina bifida	0.002	0.998	0.000
D73.0 Hyposplenism	0.000	0.998	0.002
Q10.7 Congenital malformation of orbit	0.002	0.998	0.000
Q10.6 Other congenital malformations of lachrymal apparatus	0.002	0.998	0.000
Q10.5 Congenital stenosis and stricture of lachrymal duct	0.002	0.998	0.000
Q10.4 Absence and agenesis of lachrymal apparatus	0.002	0.998	0.000
Q10.3 Other congenital malformations of eyelid	0.002	0.998	0.000
Q10.2 Congenital entropion	0.002	0.998	0.000
Q10.1 Congenital ectropion	0.002	0.998	0.000
M48.19 Ankylosing hyperostosis [Forestier] (Site unspecified)	0.002	0.998	0.000
M48.18 Ankylosing hyperostosis [Forestier] (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M48.17 Ankylosing hyperostosis [Forestier] (Lumbosacral region)	0.002	0.998	0.000
M48.16 Ankylosing hyperostosis [Forestier] (Lumbar region)	0.002	0.998	0.000
M48.15 Ankylosing hyperostosis [Forestier] (Thoracolumbar region)	0.002	0.998	0.000
M48.14 Ankylosing hyperostosis [Forestier] (Thoracic region)	0.002	0.998	0.000
M48.13 Ankylosing hyperostosis [Forestier] (Cervicothoracic region)	0.002	0.998	0.000
M48.12 Ankylosing hyperostosis [Forestier] (Cervical region)	0.002	0.998	0.000
M48.11 Ankylosing hyperostosis [Forestier] (Occipito-atlanto-axial region)	0.002	0.998	0.000
M48.10 Ankylosing hyperostosis [Forestier] (Multiple sites in spine)	0.002	0.998	0.000
M48.29 Kissing spine (Site unspecified)	0.002	0.998	0.000
M48.28 Kissing spine (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M48.27 Kissing spine (Lumbosacral region)	0.002	0.998	0.000
M48.26 Kissing spine (Lumbar region)	0.002	0.998	0.000
M48.25 Kissing spine (Thoracolumbar region)	0.002	0.998	0.000
M48.24 Kissing spine (Thoracic region)	0.002	0.998	0.000
M48.23 Kissing spine (Cervicothoracic region)	0.002	0.998	0.000
M48.22 Kissing spine (Cervical region)	0.002	0.998	0.000
M48.21 Kissing spine (Occipito-atlanto-axial region)	0.002	0.998	0.000
M48.20 Kissing spine (Multiple sites in spine)	0.002	0.998	0.000
M48.39 Traumatic spondylopathy (Site unspecified)	0.002	0.998	0.000
M48.38 Traumatic spondylopathy (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M48.37 Traumatic spondylopathy (Lumbosacral region)	0.002	0.998	0.000
M48.36 Traumatic spondylopathy (Lumbar region)	0.002	0.998	0.000
M48.35 Traumatic spondylopathy (Thoracolumbar region)	0.002	0.998	0.000
M48.34 Traumatic spondylopathy (Thoracic region)	0.002	0.998	0.000
M48.33 Traumatic spondylopathy (Cervicothoracic region)	0.002	0.998	0.000
M48.32 Traumatic spondylopathy (Cervical region)	0.002	0.998	0.000
M48.31 Traumatic spondylopathy (Occipito-atlanto-axial region)	0.002	0.998	0.000
M48.30 Traumatic spondylopathy (Multiple sites in spine)	0.002	0.998	0.000
M48.49 Fatigue fracture of vertebra (Site unspecified)	0.002	0.998	0.000
M48.48 Fatigue fracture of vertebra (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M48.47 Fatigue fracture of vertebra (Lumbosacral region)	0.002	0.998	0.000
M48.46 Fatigue fracture of vertebra (Lumbar region)	0.002	0.998	0.000
M48.45 Fatigue fracture of vertebra (Thoracolumbar region)	0.002	0.998	0.000
M48.44 Fatigue fracture of vertebra (Thoracic region)	0.002	0.998	0.000
M48.43 Fatigue fracture of vertebra (Cervicothoracic region)	0.002	0.998	0.000
M48.42 Fatigue fracture of vertebra (Cervical region)	0.002	0.998	0.000
M48.41 Fatigue fracture of vertebra (Occipito-atlanto-axial region)	0.002	0.998	0.000
M48.40 Fatigue fracture of vertebra (Multiple sites in spine)	0.002	0.998	0.000
M48.50 Collapsed vertebra, not elsewhere classified (Multiple sites in spine)	0.002	0.998	0.000
M48.89 Other specified spondylopathies (Site unspecified)	0.002	0.998	0.000
M48.88 Other specified spondylopathies (Sacral and sacrococcygeal region)	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations