TreeWAS – Variant ID: rs9985766

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K80.2 Calculus of gallbladder without cholecystitis	0.957	0.043	0.000
K80 Cholelithiasis	0.947	0.053	0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis	0.911	0.089	0.000
K80.1 Calculus of gallbladder with other cholecystitis	0.890	0.110	0.000
K80.0 Calculus of gallbladder with acute cholecystitis	0.797	0.203	0.000
K80.8 Other cholelithiasis	0.793	0.207	0.000
K80.3 Calculus of bile duct with cholangitis	0.679	0.321	0.000
K80.4 Calculus of bile duct with cholecystitis	0.545	0.455	0.000
K80.36 Calculus of bile duct with acute and chronic cholangitis without obstruction	0.487	0.513	0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.444	0.556	0.000
K82 Other diseases of gallbladder	0.420	0.580	0.000
K82.8 Other specified diseases of gallbladder	0.408	0.592	0.000
K85 Acute pancreatitis	0.380	0.620	0.000
K82.1 Hydrops of gallbladder	0.374	0.626	0.000
K85.2 Alcohol-induced acute pancreatitis	0.319	0.681	0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.318	0.681	0.000
K85.1 Biliary acute pancreatitis	0.317	0.683	0.000
K82.0 Obstruction of gallbladder	0.314	0.686	0.000
K82.3 Fistula of gallbladder	0.298	0.702	0.000
K85.0 Idiopathic acute pancreatitis	0.287	0.713	0.000
K85.3 Drug-induced acute pancreatitis	0.273	0.727	0.000
K82.4 Cholesterolosis of gallbladder	0.259	0.741	0.000
K85.8 Other acute pancreatitis	0.258	0.742	0.000
K83 Other diseases of biliary tract	0.254	0.746	0.000
K85.9 Acute pancreatitis, unspecified	0.243	0.757	0.000
K81 Cholecystitis	0.236	0.764	0.000
K82.2 Perforation of gallbladder	0.235	0.764	0.000
K87.1 Disorders of pancreas in diseases classified elsewhere	0.228	0.771	0.000
K87.0 Disorders of gallbladder and biliary tract in diseases classified elsewhere	0.228	0.771	0.000
K82.9 Disease of gallbladder, unspecified	0.218	0.781	0.000
K81.9 Cholecystitis, unspecified	0.200	0.800	0.000
K83.1 Obstruction of bile duct	0.197	0.803	0.000
K83.5 Biliary cyst	0.195	0.805	0.000
K83.9 Disease of biliary tract, unspecified	0.191	0.809	0.000
K83.3 Fistula of bile duct	0.185	0.814	0.000
K83.4 Spasm of sphincter of Oddi	0.182	0.817	0.000
K83.2 Perforation of bile duct	0.182	0.817	0.000
K81.8 Other cholecystitis	0.164	0.836	0.000
K83.0 Cholangitis	0.145	0.855	0.000
K81.0 Acute cholecystitis	0.119	0.881	0.000
K83.8 Other specified diseases of biliary tract	0.093	0.907	0.000
K81.1 Chronic cholecystitis	0.092	0.908	0.000
R20.2 Paraesthesia of skin	0.070	0.930	0.000
K86 Other diseases of pancreas	0.029	0.971	0.000
Z88.5 Personal history of allergy to narcotic agent	0.027	0.973	0.000
D12.5 Sigmoid colon	0.000	0.976	0.024
K86.1 Other chronic pancreatitis	0.021	0.979	0.000
Z88.6 Personal history of allergy to analgesic agent	0.021	0.979	0.000
Z88.7 Personal history of allergy to serum and vaccine	0.019	0.981	0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances	0.019	0.981	0.000
R20 Disturbances of skin sensation	0.017	0.983	0.000
K86.9 Disease of pancreas, unspecified	0.016	0.983	0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances	0.016	0.984	0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances	0.015	0.985	0.000
K86.0 Alcohol-induced chronic pancreatitis	0.013	0.986	0.000
R20.1 Hypoaesthesia of skin	0.013	0.987	0.000
R20.3 Hyperaesthesia	0.013	0.987	0.000
Z88.3 Personal history of allergy to other anti-infective agents	0.013	0.987	0.000
K86.2 Cyst of pancreas	0.012	0.988	0.000
K86.3 Pseudocyst of pancreas	0.011	0.989	0.000
R20.0 Anaesthesia of skin	0.011	0.989	0.000
Z88.1 Personal history of allergy to other antibiotic agents	0.010	0.990	0.000
N02.9 Unspecified	0.009	0.991	0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.000	0.991	0.009
Z88.4 Personal history of allergy to anaesthetic agent	0.009	0.991	0.000
K86.8 Other specified diseases of pancreas	0.008	0.992	0.000
K22.2 Oesophageal obstruction	0.008	0.992	0.000
Q61.2 Polycystic kidney, adult type	0.008	0.992	0.000
Q61 Cystic kidney disease	0.007	0.993	0.000
I42.1 Obstructive hypertrophic cardiomyopathy	0.000	0.993	0.007
Q61.9 Cystic kidney disease, unspecified	0.007	0.993	0.000
Q61.3 Polycystic kidney, unspecified	0.006	0.994	0.000
R23.3 Spontaneous ecchymoses	0.006	0.994	0.000
Z75.1 Person awaiting admission to adequate facility elsewhere	0.006	0.994	0.000
Q61.4 Renal dysplasia	0.005	0.994	0.000
T83.0 Mechanical complication of urinary (indwelling) catheter	0.006	0.994	0.000
N80.9 Endometriosis, unspecified	0.005	0.995	0.000
R23.4 Changes in skin texture	0.005	0.995	0.000
R23 Other skin changes	0.005	0.995	0.000
Q61.8 Other cystic kidney diseases	0.005	0.995	0.000
Q61.1 Polycystic kidney, infantile type	0.005	0.995	0.000
Q61.0 Congenital single renal cyst	0.005	0.995	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.005	0.995	0.000
Z88.2 Personal history of allergy to sulphonamides	0.005	0.995	0.000
I42 Cardiomyopathy	0.000	0.995	0.005
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.005	0.995	0.000
I42.2 Other hypertrophic cardiomyopathy	0.000	0.995	0.005
Q60-Q64 Congenital malformations of the urinary system	0.005	0.995	0.000
R23.0 Cyanosis	0.004	0.995	0.000
I42.6 Alcoholic cardiomyopathy	0.000	0.996	0.004
I42.0 Dilated cardiomyopathy	0.000	0.996	0.004
C79.2 Secondary malignant neoplasm of skin	0.000	0.996	0.004
C79 Secondary malignant neoplasm of other sites	0.000	0.996	0.004
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.000	0.996	0.004
Q61.5 Medullary cystic kidney	0.004	0.996	0.000
G93.9 Disorder of brain, unspecified	0.004	0.996	0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.004	0.996	0.000
M22.8 Other disorders of patella	0.000	0.996	0.004
I42.8 Other cardiomyopathies	0.000	0.996	0.004
Q62.5 Duplication of ureter	0.004	0.996	0.000
M75.0 Adhesive capsulitis of shoulder	0.004	0.996	0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.000	0.996	0.004
I42.7 Cardiomyopathy due to drugs and other external agents	0.000	0.996	0.004
I42.5 Other restrictive cardiomyopathy	0.000	0.996	0.004
I42.4 Endocardial fibroelastosis	0.000	0.996	0.004
I42.3 Endomyocardial (eosinophilic) disease	0.000	0.996	0.004
I42.9 Cardiomyopathy, unspecified	0.000	0.996	0.004
C79.8 Secondary malignant neoplasm of other specified sites	0.000	0.996	0.004
M19.90 Arthrosis, unspecified (Multiple sites)	0.004	0.996	0.000
R23.2 Flushing	0.004	0.996	0.000
Q50.4 Embryonic cyst of Fallopian tube	0.000	0.996	0.004
Q64 Other congenital malformations of urinary system	0.003	0.997	0.000
Y84.1 Kidney dialysis	0.003	0.997	0.000
M43.16 Spondylolisthesis (Lumbar region)	0.003	0.997	0.000
Q62.8 Other congenital malformations of ureter	0.003	0.997	0.000
Q62.7 Congenital vesico-uretero-renal reflux	0.003	0.997	0.000
Q62.6 Malposition of ureter	0.003	0.997	0.000
Q62.4 Agenesis of ureter	0.003	0.997	0.000
Q62.3 Other obstructive defects of renal pelvis and ureter	0.003	0.997	0.000
Q62.2 Congenital megaloureter	0.003	0.997	0.000
Q62.1 Atresia and stenosis of ureter	0.003	0.997	0.000
Q62.0 Congenital hydronephrosis	0.003	0.997	0.000
M88.90 Paget's disease of bone, unspecified (Multiple sites)	0.003	0.997	0.000
Z75 Problems related to medical facilities and other health care	0.003	0.997	0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs	0.000	0.997	0.003
D09.0 Bladder	0.003	0.997	0.000
R23.1 Pallor	0.003	0.997	0.000
I46.0 Cardiac arrest with successful resuscitation	0.000	0.997	0.003
C79.9 Secondary malignant neoplasm, unspecified site	0.000	0.997	0.003
D41.4 Bladder	0.000	0.997	0.003
Q63 Other congenital malformations of kidney	0.003	0.997	0.000
E53.8 Deficiency of other specified B group vitamins	0.003	0.997	0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral	0.003	0.997	0.000
Q44.6 Cystic disease of liver	0.003	0.997	0.000
M77.91 Enthesopathy, unspecified (Shoulder region)	0.003	0.997	0.000
K51.8 Other ulcerative colitis	0.000	0.997	0.003
Z75.3 Unavailability and inaccessibility of health-care facilities	0.003	0.997	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.003	0.997	0.000
R23.8 Other and unspecified skin changes	0.003	0.997	0.000
N02 Recurrent and persistent haematuria	0.003	0.997	0.000
Z75.2 Other waiting period for investigation and treatment	0.003	0.997	0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.003	0.997	0.000
J86.9 Pyothorax without fistula	0.003	0.997	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.003	0.997	0.000
N83.8 Other noninflammatory disorders of ovary, Fallopian tube and broad ligament	0.000	0.997	0.003
G93 Other disorders of brain	0.003	0.997	0.000
M43.19 Spondylolisthesis (Site unspecified)	0.003	0.997	0.000
R20.8 Other and unspecified disturbances of skin sensation	0.003	0.997	0.000
Q64.9 Congenital malformation of urinary system, unspecified	0.003	0.997	0.000
Q64.8 Other specified congenital malformations of urinary system	0.003	0.997	0.000
Q64.7 Other congenital malformations of bladder and urethra	0.003	0.997	0.000
Q64.6 Congenital diverticulum of bladder	0.003	0.997	0.000
Q64.5 Congenital absence of bladder and urethra	0.003	0.997	0.000
Q64.4 Malformation of urachus	0.003	0.997	0.000
Q64.2 Congenital posterior urethral valves	0.003	0.997	0.000
Q64.1 Exstrophy of urinary bladder	0.003	0.997	0.000
Q64.0 Epispadias	0.003	0.997	0.000
T83.2 Mechanical complication of graft of urinary organ	0.003	0.997	0.000
M43.1 Spondylolisthesis	0.003	0.997	0.000
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.003	0.997	0.000
Q87.8 Other specified congenital malformation syndromes, not elsewhere classified	0.003	0.997	0.000
Q66.8 Other congenital deformities of feet	0.000	0.997	0.003
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.003	0.997	0.000
Q64.3 Other atresia and stenosis of urethra and bladder neck	0.003	0.997	0.000
G93.0 Cerebral cysts	0.003	0.997	0.000
Q63.1 Lobulated, fused and horseshoe kidney	0.003	0.997	0.000
M18.1 Other primary arthrosis of first carpometacarpal joint	0.003	0.997	0.000
Z75.9 Unspecified problem related to medical facilities and other health care	0.003	0.997	0.000
Z75.0 Medical services not available in home	0.003	0.997	0.000
G93.3 Postviral fatigue syndrome	0.003	0.997	0.000
Z29.8 Other specified prophylactic measures	0.000	0.997	0.003
C79.6 Secondary malignant neoplasm of ovary	0.000	0.997	0.002
G93.6 Cerebral oedema	0.003	0.997	0.000
Z75.4 Unavailability and inaccessibility of other helping agencies	0.002	0.997	0.000
Q74.1 Congenital malformation of knee	0.002	0.997	0.000
Z75.5 Holiday relief care	0.002	0.997	0.000
Q74 Other congenital malformations of limb(s)	0.002	0.997	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.003	0.997	0.000
Q63.9 Congenital malformation of kidney, unspecified	0.002	0.997	0.000
Q63.8 Other specified congenital malformations of kidney	0.002	0.997	0.000
Q63.3 Hyperplastic and giant kidney	0.002	0.997	0.000
Q63.2 Ectopic kidney	0.002	0.997	0.000
Q96.9 Turner's syndrome, unspecified	0.002	0.997	0.000
T83.1 Mechanical complication of other urinary devices and implants	0.002	0.997	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.002	0.997	0.000
Q44.4 Choledochal cyst	0.002	0.998	0.000
Q74.0 Other congenital malformations of upper limb(s), including shoulder girdle	0.002	0.998	0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.002	0.998	0.000
W22.9 Unspecified place	0.002	0.998	0.000
Z75.8 Other problems related to medical facilities and other health care	0.002	0.998	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.000	0.998	0.002
Q80-Q89 Other congenital malformations	0.002	0.998	0.000
Q27.3 Peripheral arteriovenous malformation	0.002	0.998	0.000
Q96 Turner's syndrome	0.002	0.998	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.002	0.998	0.000
E07.9 Disorder of thyroid, unspecified	0.002	0.998	0.000
Q87.1 Congenital malformation syndromes predominantly associated with short stature	0.002	0.998	0.000
G93.2 Benign intracranial hypertension	0.002	0.998	0.000
Q60.6 Potter's syndrome	0.002	0.998	0.000
Q60.5 Renal hypoplasia, unspecified	0.002	0.998	0.000
Q60.4 Renal hypoplasia, bilateral	0.002	0.998	0.000
Q60.3 Renal hypoplasia, unilateral	0.002	0.998	0.000
Q60.1 Renal agenesis, bilateral	0.002	0.998	0.000
Q87.4 Marfan's syndrome	0.002	0.998	0.000
N02.7 Diffuse crescentic glomerulonephritis	0.002	0.998	0.000
N02.6 Dense deposit disease	0.002	0.998	0.000
N02.5 Diffuse mesangiocapillary glomerulonephritis	0.002	0.998	0.000
N02.4 Diffuse endocapillary proliferative glomerulonephritis	0.002	0.998	0.000
N02.3 Diffuse mesangial proliferative glomerulonephritis	0.002	0.998	0.000
N02.2 Diffuse membranous glomerulonephritis	0.002	0.998	0.000
N02.1 Focal and segmental glomerular lesions	0.002	0.998	0.000
N02.0 Minor glomerular abnormality	0.002	0.998	0.000
R05 Cough	0.002	0.998	0.000
S02.30 Fracture of orbital floor (closed)	0.002	0.998	0.000
Q44.5 Other congenital malformations of bile ducts	0.002	0.998	0.000
Q39 Congenital malformations of oesophagus	0.002	0.998	0.000
H18.5 Hereditary corneal dystrophies	0.000	0.998	0.002
J86.0 Pyothorax with fistula	0.002	0.998	0.000
Q44.7 Other congenital malformations of liver	0.002	0.998	0.000
Q44.3 Congenital stenosis and stricture of bile ducts	0.002	0.998	0.000
Q44.2 Atresia of bile ducts	0.002	0.998	0.000
Q44.1 Other congenital malformations of gallbladder	0.002	0.998	0.000
Q44.0 Agenesis, aplasia and hypoplasia of gallbladder	0.002	0.998	0.000
G93.7 Reye's syndrome	0.002	0.998	0.000
M77.9 Enthesopathy, unspecified	0.002	0.998	0.000
M88.9 Paget's disease of bone, unspecified	0.002	0.998	0.000
M43.17 Spondylolisthesis (Lumbosacral region)	0.002	0.998	0.000
M43.18 Spondylolisthesis (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M43.15 Spondylolisthesis (Thoracolumbar region)	0.002	0.998	0.000
M43.14 Spondylolisthesis (Thoracic region)	0.002	0.998	0.000
M43.13 Spondylolisthesis (Cervicothoracic region)	0.002	0.998	0.000
M43.11 Spondylolisthesis (Occipito-atlanto-axial region)	0.002	0.998	0.000
M43.10 Spondylolisthesis (Multiple sites in spine)	0.002	0.998	0.000
Q24.5 Malformation of coronary vessels	0.002	0.998	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.002	0.998	0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract	0.002	0.998	0.000
Q60.2 Renal agenesis, unspecified	0.002	0.998	0.000
Q87.5 Other congenital malformation syndromes with other skeletal changes	0.002	0.998	0.000
Q87.3 Congenital malformation syndromes involving early overgrowth	0.002	0.998	0.000
Q87.2 Congenital malformation syndromes predominantly involving limbs	0.002	0.998	0.000
Q87.0 Congenital malformation syndromes predominantly affecting facial appearance	0.002	0.998	0.000
J86 Pyothorax	0.002	0.998	0.000
M18 Arthrosis of first carpometacarpal joint	0.002	0.998	0.000
G93.8 Other specified disorders of brain	0.002	0.998	0.000
Q27 Other congenital malformations of peripheral vascular system	0.002	0.998	0.000
Q45 Other congenital malformations of digestive system	0.002	0.998	0.000
Q35-Q37 Cleft lip and cleft palate	0.002	0.998	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.002	0.998	0.000
M77.95 Enthesopathy, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
F43.9 Reaction to severe stress, unspecified	0.002	0.998	0.000
G95.9 Disease of spinal cord, unspecified	0.002	0.998	0.000
Z09.0 Follow-up examination after surgery for other conditions	0.000	0.998	0.002
R72 Abnormality of white blood cells, not elsewhere classified	0.000	0.998	0.002
M43.12 Spondylolisthesis (Cervical region)	0.002	0.998	0.000
Q39.6 Diverticulum of oesophagus	0.002	0.998	0.000
Q74.2 Other congenital malformations of lower limb(s), including pelvic girdle	0.002	0.998	0.000
Q74.9 Unspecified congenital malformation of limb(s)	0.002	0.998	0.000
Q74.8 Other specified congenital malformations of limb(s)	0.002	0.998	0.000
Q74.3 Arthrogryposis multiplex congenita	0.002	0.998	0.000
V49.9 Car occupant [any] injured in unspecified traffic accident	0.002	0.998	0.000
S01.5 Open wound of lip and oral cavity	0.002	0.998	0.000
I22 Subsequent myocardial infarction	0.002	0.998	0.000
Q28 Other congenital malformations of circulatory system	0.002	0.998	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.002	0.998	0.000
E53 Deficiency of other B group vitamins	0.002	0.998	0.000
Q24 Other congenital malformations of heart	0.002	0.998	0.000
Q66 Congenital deformities of feet	0.001	0.998	0.001
Q90 Down's syndrome	0.002	0.998	0.000
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint	0.002	0.998	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.002	0.998	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.002	0.998	0.000
M77.94 Enthesopathy, unspecified (Hand)	0.002	0.998	0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
Q39.4 Oesophageal web	0.002	0.998	0.000
Q50.6 Other congenital malformatons of Fallopian tube and broad ligament	0.000	0.998	0.002
Q50.3 Other congenital malformations of ovary	0.000	0.998	0.002
Q50.2 Congenital torsion of ovary	0.000	0.998	0.002
Q50.1 Developmental ovarian cyst	0.000	0.998	0.002
Q50.0 Congenital absence of ovary	0.000	0.998	0.002
M75.2 Bicipital tendinitis	0.002	0.998	0.000
Q45.3 Other congenital malformations of pancreas and pancreatic duct	0.002	0.998	0.000
Z97.8 Presence of other specified devices	0.002	0.998	0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.002	0.998	0.000
Q84 Other congenital malformations of integument	0.002	0.998	0.000
Q81 Epidermolysis bullosa	0.002	0.998	0.000
Q80 Congenital ichthyosis	0.002	0.998	0.000
Q28.2 Arteriovenous malformation of cerebral vessels	0.002	0.998	0.000
Q60.0 Renal agenesis, unilateral	0.002	0.998	0.000
Q96.8 Other variants of Turner's syndrome	0.002	0.998	0.000
Q96.4 Mosaicism, 45,X/other cell line(s) with abnormal sex chromosome	0.002	0.998	0.000
Q96.3 Mosaicism, 45,X/46,XX or XY	0.002	0.998	0.000
Q96.2 Karyotype 46,X with abnormal sex chromosome, except iso (Xq)	0.002	0.998	0.000
Q96.1 Karyotype 46,X iso (Xq)	0.002	0.998	0.000
Q96.0 Karyotype 45,X	0.002	0.998	0.000
Q82 Other congenital malformations of skin	0.002	0.998	0.000
Q99 Other chromosome abnormalities, not elsewhere classified	0.002	0.998	0.000
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified	0.002	0.998	0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified	0.002	0.998	0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified	0.002	0.998	0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified	0.002	0.998	0.000
Q91 Edwards' syndrome and Patau's syndrome	0.002	0.998	0.000
G93.5 Compression of brain	0.002	0.998	0.000
Q37 Cleft palate with cleft lip	0.002	0.998	0.000
Q40 Other congenital malformations of upper alimentary tract	0.002	0.998	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.002	0.998	0.000
Q89 Other congenital malformations, not elsewhere classified	0.002	0.998	0.000
M13.97 Arthritis, unspecified (Ankle and foot)	0.002	0.998	0.000
M40.29 Other and unspecified kyphosis (Site unspecified)	0.002	0.998	0.000
M88.99 Paget's disease of bone, unspecified (Site unspecified)	0.002	0.998	0.000
E53.9 Vitamin B deficiency, unspecified	0.002	0.998	0.000
Q50.5 Embryonic cyst of broad ligament	0.000	0.998	0.002
Q25 Congenital malformations of great arteries	0.002	0.998	0.000
C79.7 Secondary malignant neoplasm of adrenal gland	0.000	0.998	0.002
M75.4 Impingement syndrome of shoulder	0.002	0.998	0.000
Q39.9 Congenital malformation of oesophagus, unspecified	0.002	0.998	0.000
Q39.8 Other congenital malformations of oesophagus	0.002	0.998	0.000
Q39.5 Congenital dilatation of oesophagus	0.002	0.998	0.000
Q39.3 Congenital stenosis and stricture of oesophagus	0.002	0.998	0.000
Q39.2 Congenital tracheooesophageal fistula without atresia	0.002	0.998	0.000
Q39.1 Atresia of oesophagus with tracheooesophageal fistula	0.002	0.998	0.000
Q39.0 Atresia of oesophagus without fistula	0.002	0.998	0.000
S05.3 Ocular laceration without prolapse or loss of intraocular tissue	0.002	0.998	0.000
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.002	0.998	0.000
S13.4 Sprain and strain of cervical spine	0.002	0.998	0.000
M77.99 Enthesopathy, unspecified (Site unspecified)	0.002	0.998	0.000
M77.98 Enthesopathy, unspecified (Other)	0.002	0.998	0.000
M77.93 Enthesopathy, unspecified (Forearm)	0.002	0.998	0.000
M77.92 Enthesopathy, unspecified (Upper arm)	0.002	0.998	0.000
M77.90 Enthesopathy, unspecified (Multiple sites)	0.002	0.998	0.000
M88.98 Paget's disease of bone, unspecified (Other)	0.002	0.998	0.000
M88.97 Paget's disease of bone, unspecified (Ankle and foot)	0.002	0.998	0.000
M88.96 Paget's disease of bone, unspecified (Lower leg)	0.002	0.998	0.000
M88.94 Paget's disease of bone, unspecified (Hand)	0.002	0.998	0.000
M88.93 Paget's disease of bone, unspecified (Forearm)	0.002	0.998	0.000
M88.92 Paget's disease of bone, unspecified (Upper arm)	0.002	0.998	0.000
M88.91 Paget's disease of bone, unspecified (Shoulder region)	0.002	0.998	0.000
S01.1 Open wound of eyelid and periocular area	0.002	0.998	0.000
T83.3 Mechanical complication of intra-uterine contraceptive device	0.002	0.998	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.002	0.998	0.000
Q75 Other congenital malformations of skull and face bones	0.002	0.998	0.000
Q73 Reduction defects of unspecified limb	0.002	0.998	0.000
Q72 Reduction defects of lower limb	0.002	0.998	0.000
Q71 Reduction defects of upper limb	0.002	0.998	0.000
Q70 Syndactyly	0.002	0.998	0.000
Q69 Polydactyly	0.002	0.998	0.000
Q68 Other congenital musculoskeletal deformities	0.002	0.998	0.000
K29.3 Chronic superficial gastritis	0.002	0.998	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.002	0.998	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.002	0.998	0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.002	0.998	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.002	0.998	0.000
M18.5 Other secondary arthrosis of first carpometacarpal joint	0.002	0.998	0.000
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral	0.002	0.998	0.000
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral	0.002	0.998	0.000
Q26 Congenital malformations of great veins	0.002	0.998	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.002	0.998	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.002	0.998	0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
M88.95 Paget's disease of bone, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
Q27.4 Congenital phlebectasia	0.002	0.998	0.000
Q27.2 Other congenital malformations of renal artery	0.002	0.998	0.000
Q27.1 Congenital renal artery stenosis	0.002	0.998	0.000
Q27.0 Congenital absence and hypoplasia of umbilical artery	0.002	0.998	0.000
Q45.9 Congenital malformation of digestive system, unspecified	0.002	0.998	0.000
Q45.8 Other specified congenital malformations of digestive system	0.002	0.998	0.000
Q45.2 Congenital pancreatic cyst	0.002	0.998	0.000
Q45.1 Annular pancreas	0.002	0.998	0.000
Q45.0 Agenesis, aplasia and hypoplasia of pancreas	0.002	0.998	0.000
Z96.6 Presence of orthopaedic joint implants	0.002	0.998	0.000
Q36 Cleft lip	0.002	0.998	0.000
Q35 Cleft palate	0.002	0.998	0.000
Q83 Congenital malformations of breast	0.002	0.998	0.000
C22.9 Liver, unspecified	0.000	0.998	0.002
Q37.9 Unspecified cleft palate with unilateral cleft lip	0.002	0.998	0.000
Q82.2 Mastocytosis	0.002	0.998	0.000
Q24.6 Congenital heart block	0.002	0.998	0.000
Q90.9 Down's syndrome, unspecified	0.002	0.998	0.000
R21 Rash and other nonspecific skin eruption	0.002	0.998	0.000
A63.0 Anogenital (venereal) warts	0.002	0.998	0.000
Q79.8 Other congenital malformations of musculoskeletal system	0.002	0.998	0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.002	0.998	0.000
Y84.9 Medical procedure, unspecified	0.002	0.998	0.000
Q85 Phakomatoses, not elsewhere classified	0.002	0.998	0.000
Q50-Q56 Congenital malformations of genital organs	0.001	0.998	0.001
M77.96 Enthesopathy, unspecified (Lower leg)	0.002	0.998	0.000
G93.1 Anoxic brain damage, not elsewhere classified	0.002	0.998	0.000
Q28.9 Congenital malformation of circulatory system, unspecified	0.002	0.998	0.000
Q28.8 Other specified congenital malformations of circulatory system	0.002	0.998	0.000
Q28.3 Other malformations of cerebral vessels	0.002	0.998	0.000
Q28.1 Other malformations of precerebral vessels	0.002	0.998	0.000
Q28.0 Arteriovenous malformation of precerebral vessels	0.002	0.998	0.000
Q38.0 Congenital malformations of lips, not elsewhere classified	0.002	0.998	0.000
Q67.5 Congenital deformity of spine	0.002	0.998	0.000
Q82.0 Hereditary lymphoedema	0.002	0.998	0.000
Q34 Other congenital malformations of respiratory system	0.002	0.998	0.000
Q33 Congenital malformations of lung	0.002	0.998	0.000
Q32 Congenital malformations of trachea and bronchus	0.002	0.998	0.000
Q31 Congenital malformations of larynx	0.002	0.998	0.000
Q30 Congenital malformations of nose	0.002	0.998	0.000
Q78 Other osteochondrodysplasias	0.001	0.998	0.000
Q76 Congenital malformations of spine and bony thorax	0.002	0.998	0.000
E53.1 Pyridoxine deficiency	0.002	0.998	0.000
E53.0 Riboflavin deficiency	0.002	0.998	0.000
Q24.4 Congenital subaortic stenosis	0.002	0.998	0.000
Q24.3 Pulmonary infundibular stenosis	0.002	0.998	0.000
Q24.2 Cor triatriatum	0.002	0.998	0.000
Q24.1 Levocardia	0.002	0.998	0.000
Q24.0 Dextrocardia	0.002	0.998	0.000
Q63.0 Accessory kidney	0.002	0.998	0.000
Q90.2 Trisomy 21, translocation	0.002	0.998	0.000
Q90.1 Trisomy 21, mosaicism (mitotic nondisjunction)	0.002	0.998	0.000
Q90.0 Trisomy 21, meiotic nondisjunction	0.002	0.998	0.000
Y84.3 Shock therapy	0.002	0.998	0.000
Z90.1 Acquired absence of breast(s)	0.002	0.998	0.000
M75 Shoulder lesions	0.002	0.998	0.000
Q41.9 Congenital absence, atresia and stenosis of small intestine, part unspecified	0.001	0.998	0.000
Q41.8 Congenital absence, atresia and stenosis of other specified parts of small intestine	0.001	0.998	0.000
Q41.2 Congenital absence, atresia and stenosis of ileum	0.001	0.998	0.000
Q41.1 Congenital absence, atresia and stenosis of jejunum	0.001	0.998	0.000
Q41.0 Congenital absence, atresia and stenosis of duodenum	0.001	0.998	0.000
Q42.9 Congenital absence, atresia and stenosis of large intestine, part unspecified	0.001	0.998	0.000
Q42.8 Congenital absence, atresia and stenosis of other parts of large intestine	0.001	0.998	0.000
Q42.3 Congenital absence, atresia and stenosis of anus without fistula	0.001	0.998	0.000
Q42.2 Congenital absence, atresia and stenosis of anus with fistula	0.001	0.998	0.000
Q42.1 Congenital absence, atresia and stenosis of rectum without fistula	0.001	0.998	0.000
Q42.0 Congenital absence, atresia and stenosis of rectum with fistula	0.001	0.998	0.000
Q66.6 Other congenital valgus deformities of feet	0.001	0.998	0.001
Q66.5 Congenital pes planus	0.001	0.998	0.001
Q66.4 Talipes calcaneovalgus	0.001	0.998	0.001
Q66.1 Talipes calcaneovarus	0.001	0.998	0.001
Q66.0 Talipes equinovarus	0.001	0.998	0.001
M13.96 Arthritis, unspecified (Lower leg)	0.002	0.998	0.000
Q66.3 Other congenital varus deformities of feet	0.001	0.998	0.001
Q80.9 Congenital ichthyosis, unspecified	0.001	0.998	0.000
Q80.8 Other congenital ichthyosis	0.001	0.998	0.000
Q80.4 Harlequin foetus	0.001	0.998	0.000
Q80.3 Congenital bullous ichthyosiform erythroderma	0.001	0.998	0.000
Q80.2 Lamellar ichthyosis	0.001	0.998	0.000
Q80.1 X-linked ichthyosis	0.001	0.998	0.000
Q80.0 Ichthyosis vulgaris	0.001	0.998	0.000
Q81.9 Epidermolysis bullosa, unspecified	0.001	0.998	0.000
Q81.8 Other epidermolysis bullosa	0.001	0.998	0.000
Q81.2 Epidermolysis bullosa dystrophica	0.001	0.998	0.000
Q81.1 Epidermolysis bullosa letalis	0.001	0.998	0.000
Q81.0 Epidermolysis bullosa simplex	0.001	0.998	0.000
Q84.9 Congenital malformation of integument, unspecified	0.001	0.998	0.000
Q84.8 Other specified congenital malformations of integument	0.001	0.998	0.000
Q84.6 Other congenital malformations of nails	0.001	0.998	0.000
Q84.5 Enlarged and hypertrophic nails	0.001	0.998	0.000
Q84.4 Congenital leukonychia	0.001	0.998	0.000
Q84.3 Anonychia	0.001	0.998	0.000
Q84.2 Other congenital malformations of hair	0.001	0.998	0.000
Q84.1 Congenital morphological disturbances of hair, not elsewhere classified	0.001	0.998	0.000
Q84.0 Congenital alopecia	0.001	0.998	0.000
Q86.8 Other congenital malformation syndromes due to known exogenous causes	0.001	0.998	0.000
Q86.2 Dysmorphism due to warfarin	0.001	0.998	0.000
Q86.1 Foetal hydantoin syndrome	0.001	0.998	0.000
Q86.0 Foetal alcohol syndrome (dysmorphic)	0.001	0.998	0.000
M77.47 Metatarsalgia-Ankle/Foot	0.002	0.998	0.000
Q25.4 Other congenital malformations of aorta	0.002	0.998	0.000
Q25.0 Patent ductus arteriosus	0.002	0.998	0.000
Q66.9 Congenital deformity of feet, unspecified	0.001	0.998	0.001
Q67.4 Other congenital deformities of skull, face and jaw	0.001	0.998	0.000
Q82.9 Congenital malformation of skin, unspecified	0.002	0.998	0.000
Q82.4 Ectodermal dysplasia (anhidrotic)	0.002	0.998	0.000
Q82.3 Incontinentia pigmenti	0.002	0.998	0.000
Q82.1 Xeroderma pigmentosum	0.002	0.998	0.000
Q91.7 Patau's syndrome, unspecified	0.001	0.998	0.000
Q91.6 Trisomy 13, translocation	0.001	0.998	0.000
Q91.5 Trisomy 13, mosaicism (mitotic nondisjunction)	0.001	0.998	0.000
Q91.4 Trisomy 13, meiotic nondisjunction	0.001	0.998	0.000
Q91.3 Edwards' syndrome, unspecified	0.001	0.998	0.000
Q91.2 Trisomy 18, translocation	0.001	0.998	0.000
Q91.1 Trisomy 18, mosaicism (mitotic nondisjunction)	0.001	0.998	0.000
Q91.0 Trisomy 18, meiotic nondisjunction	0.001	0.998	0.000
Q92.9 Trisomy and partial trisomy of autosomes, unspecified	0.001	0.998	0.000
Q92.8 Other specified trisomies and partial trisomies of autosomes	0.001	0.998	0.000
Q92.7 Triploidy and polyploidy	0.001	0.998	0.000
Q92.6 Extra marker chromosomes	0.001	0.998	0.000
Q92.5 Duplications with other complex rearrangements	0.001	0.998	0.000
Q92.4 Duplications seen only at prometaphase	0.001	0.998	0.000
Q92.3 Minor partial trisomy	0.001	0.998	0.000
Q92.2 Major partial trisomy	0.001	0.998	0.000
Q92.1 Whole chromosome trisomy, mosaicism (mitotic nondisjunction)	0.001	0.998	0.000
Q92.0 Whole chromosome trisomy, meiotic nondisjunction	0.001	0.998	0.000
Q93.9 Deletion from autosomes, unspecified	0.001	0.998	0.000
Q93.8 Other deletions from the autosomes	0.001	0.998	0.000
Q93.7 Deletions with other complex rearrangements	0.001	0.998	0.000
Q93.6 Deletions seen only at prometaphase	0.001	0.998	0.000
Q93.5 Other deletions of part of a chromosome	0.001	0.998	0.000
Q93.4 Deletion of short arm of chromosome 5	0.001	0.998	0.000
Q93.3 Deletion of short arm of chromosome 4	0.001	0.998	0.000
Q93.2 Chromosome replaced with ring or dicentric	0.001	0.998	0.000
Q93.1 Whole chromosome monosomy, mosaicism (mitotic nondisjunction)	0.001	0.998	0.000
Q93.0 Whole chromosome monosomy, meiotic nondisjunction	0.001	0.998	0.000
Q95.9 Balanced rearrangement and structural marker, unspecified	0.001	0.998	0.000
Q95.8 Other balanced rearrangements and structural markers	0.001	0.998	0.000
Q95.5 Individuals with autosomal fragile site	0.001	0.998	0.000
Q95.4 Individuals with marker heterochromatin	0.001	0.998	0.000
Q95.3 Balanced sex/autosomal rearrangement in abnormal individual	0.001	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations