TreeWAS – Variant ID: Affx-20090607

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K80.1 Calculus of gallbladder with other cholecystitis	1.000	0.000	0.000
K80 Cholelithiasis	1.000	0.000	0.000
E78.0 Pure hypercholesterolaemia	0.000	0.000	1.000
K80.2 Calculus of gallbladder without cholecystitis	1.000	0.000	0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis	0.999	0.001	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.000	0.025	0.975
K80.0 Calculus of gallbladder with acute cholecystitis	0.975	0.025	0.000
E78.5 Hyperlipidaemia, unspecified	0.000	0.044	0.956
E78.2 Mixed hyperlipidaemia	0.000	0.097	0.903
Z95.5 Presence of coronary angioplasty implant and graft	0.000	0.139	0.861
I25.8 Other forms of chronic ischaemic heart disease	0.000	0.147	0.853
I25 Chronic ischaemic heart disease	0.000	0.147	0.853
I25.1 Atherosclerotic heart disease	0.000	0.150	0.850
I25.2 Old myocardial infarction	0.000	0.239	0.761
I25.9 Chronic ischaemic heart disease, unspecified	0.000	0.245	0.755
K80.4 Calculus of bile duct with cholecystitis	0.746	0.254	0.000
E78.8 Other disorders of lipoprotein metabolism	0.000	0.273	0.727
K80.3 Calculus of bile duct with cholangitis	0.717	0.283	0.000
E78.1 Pure hyperglyceridaemia	0.000	0.286	0.714
I25.3 Aneurysm of heart	0.000	0.289	0.711
E78.6 Lipoprotein deficiency	0.000	0.301	0.699
E78.3 Hyperchylomicronaemia	0.000	0.301	0.699
E78.9 Disorder of lipoprotein metabolism, unspecified	0.000	0.320	0.680
E78.4 Other hyperlipidaemia	0.000	0.346	0.654
I25.0 Atherosclerotic cardiovascular disease, so described	0.000	0.387	0.613
I25.6 Silent myocardial ischaemia	0.000	0.388	0.612
I25.4 Coronary artery aneurysm	0.000	0.475	0.524
K80.36 Calculus of bile duct with acute and chronic cholangitis without obstruction	0.514	0.486	0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.501	0.499	0.000
I20-I25 Ischaemic heart diseases	0.000	0.510	0.490
K82 Other diseases of gallbladder	0.489	0.511	0.000
K82.8 Other specified diseases of gallbladder	0.480	0.520	0.000
I22 Subsequent myocardial infarction	0.000	0.564	0.436
K80.8 Other cholelithiasis	0.434	0.566	0.000
K81 Cholecystitis	0.429	0.571	0.000
K82.1 Hydrops of gallbladder	0.380	0.620	0.000
K81.9 Cholecystitis, unspecified	0.378	0.622	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.000	0.625	0.375
I22.9 Subsequent myocardial infarction of unspecified site	0.000	0.633	0.367
K82.2 Perforation of gallbladder	0.364	0.636	0.000
K81.1 Chronic cholecystitis	0.361	0.639	0.000
K82.3 Fistula of gallbladder	0.360	0.640	0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.359	0.641	0.000
K82.4 Cholesterolosis of gallbladder	0.357	0.643	0.000
I20 Angina pectoris	0.000	0.645	0.355
I21 Acute myocardial infarction	0.000	0.659	0.341
I23 Certain current complications following acute myocardial infarction	0.000	0.662	0.338
I22.8 Subsequent myocardial infarction of other sites	0.000	0.665	0.335
K82.9 Disease of gallbladder, unspecified	0.329	0.670	0.000
I25.5 Ischaemic cardiomyopathy	0.000	0.670	0.329
K81.8 Other cholecystitis	0.327	0.672	0.000
I20.0 Unstable angina	0.000	0.679	0.321
K82.0 Obstruction of gallbladder	0.320	0.680	0.000
I21.9 Acute myocardial infarction, unspecified	0.000	0.682	0.318
I21.1 Acute transmural myocardial infarction of inferior wall	0.000	0.692	0.308
I22.0 Subsequent myocardial infarction of anterior wall	0.000	0.734	0.266
I35 Nonrheumatic aortic valve disorders	0.000	0.738	0.262
I35.2 Aortic (valve) stenosis with insufficiency	0.000	0.741	0.259
K87.1 Disorders of pancreas in diseases classified elsewhere	0.258	0.742	0.000
K87.0 Disorders of gallbladder and biliary tract in diseases classified elsewhere	0.258	0.742	0.000
I35.0 Aortic (valve) stenosis	0.000	0.748	0.252
I20.9 Angina pectoris, unspecified	0.000	0.752	0.248
I21.X Presumed acute myicardial infaction (unconfirmed)	0.000	0.756	0.244
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.000	0.757	0.242
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.000	0.757	0.242
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.000	0.757	0.242
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.000	0.757	0.242
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.000	0.757	0.242
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.000	0.757	0.242
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.000	0.757	0.242
K85 Acute pancreatitis	0.238	0.762	0.000
I35.9 Aortic valve disorder, unspecified	0.000	0.768	0.232
I21.3 Acute transmural myocardial infarction of unspecified site	0.000	0.770	0.230
I23.8 Other current complications following acute myocardial infarction	0.000	0.771	0.229
I24 Other acute ischaemic heart diseases	0.000	0.773	0.227
I35.1 Aortic (valve) insufficiency	0.000	0.773	0.227
I42 Cardiomyopathy	0.000	0.789	0.211
I30-I52 Other forms of heart disease	0.000	0.797	0.203
I20.1 Angina pectoris with documented spasm	0.000	0.798	0.201
I42.9 Cardiomyopathy, unspecified	0.000	0.799	0.201
I35.8 Other aortic valve disorders	0.000	0.805	0.195
I38 Endocarditis, valve unspecified	0.000	0.808	0.192
I42.1 Obstructive hypertrophic cardiomyopathy	0.000	0.810	0.190
K85.1 Biliary acute pancreatitis	0.187	0.813	0.000
Chapter IX Diseases of the circulatory system	0.000	0.815	0.185
I20.8 Other forms of angina pectoris	0.000	0.816	0.184
I24.9 Acute ischaemic heart disease, unspecified	0.000	0.816	0.184
I42.0 Dilated cardiomyopathy	0.000	0.821	0.179
I21.2 Acute transmural myocardial infarction of other sites	0.000	0.823	0.177
I42.2 Other hypertrophic cardiomyopathy	0.000	0.825	0.175
I42.6 Alcoholic cardiomyopathy	0.000	0.827	0.173
I31 Other diseases of pericardium	0.000	0.829	0.171
K85.3 Drug-induced acute pancreatitis	0.170	0.829	0.000
K85.0 Idiopathic acute pancreatitis	0.170	0.829	0.000
K81.0 Acute cholecystitis	0.167	0.832	0.000
I37 Pulmonary valve disorders	0.000	0.839	0.161
K85.2 Alcohol-induced acute pancreatitis	0.155	0.845	0.000
K83 Other diseases of biliary tract	0.154	0.846	0.000
I42.7 Cardiomyopathy due to drugs and other external agents	0.000	0.849	0.151
I42.5 Other restrictive cardiomyopathy	0.000	0.849	0.151
I42.4 Endocardial fibroelastosis	0.000	0.849	0.151
I42.3 Endomyocardial (eosinophilic) disease	0.000	0.849	0.151
I42.8 Other cardiomyopathies	0.000	0.849	0.151
I31.9 Disease of pericardium, unspecified	0.000	0.850	0.150
I05-I09 Chronic rheumatic heart diseases	0.000	0.852	0.148
I52 Other heart disorders in diseases classified elsewhere	0.000	0.854	0.146
I48 Atrial fibrillation and flutter	0.000	0.854	0.146
I41 Myocarditis in diseases classified elsewhere	0.000	0.854	0.146
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.000	0.854	0.146
I32 Pericarditis in diseases classified elsewhere	0.000	0.854	0.146
I24.1 Dressler's syndrome	0.000	0.854	0.146
I33 Acute and subacute endocarditis	0.000	0.856	0.144
I51.7 Cardiomegaly	0.000	0.856	0.144
I24.8 Other forms of acute ischaemic heart disease	0.000	0.857	0.143
K85.8 Other acute pancreatitis	0.142	0.858	0.000
I51 Complications and ill-defined descriptions of heart disease	0.000	0.858	0.142
I30 Acute pericarditis	0.000	0.859	0.141
I43 Cardiomyopathy in diseases classified elsewhere	0.000	0.861	0.139
I40 Acute myocarditis	0.000	0.865	0.134
I37.1 Pulmonary valve insufficiency	0.000	0.869	0.131
I07 Rheumatic tricuspid valve diseases	0.000	0.869	0.131
I36 Nonrheumatic tricuspid valve disorders	0.000	0.869	0.131
I00-I02 Acute rheumatic fever	0.000	0.869	0.131
K83.3 Fistula of bile duct	0.130	0.870	0.000
I31.0 Chronic adhesive pericarditis	0.000	0.873	0.127
I31.1 Chronic constrictive pericarditis	0.000	0.876	0.124
I31.8 Other specified diseases of pericardium	0.000	0.877	0.123
I31.2 Haemopericardium, not elsewhere classified	0.000	0.877	0.123
I07.1 Tricuspid insufficiency	0.000	0.881	0.119
I30.1 Infective pericarditis	0.000	0.884	0.116
I37.9 Pulmonary valve disorder, unspecified	0.000	0.884	0.116
I37.8 Other pulmonary valve disorders	0.000	0.884	0.116
I37.2 Pulmonary valve stenosis with insufficiency	0.000	0.884	0.116
I37.0 Pulmonary valve stenosis	0.000	0.884	0.116
I31.3 Pericardial effusion (noninflammatory)	0.000	0.884	0.116
I46 Cardiac arrest	0.000	0.886	0.114
I33.0 Acute and subacute infective endocarditis	0.000	0.887	0.112
I51.0 Cardiac septal defect, acquired	0.000	0.887	0.112
I95-I99 Other and unspecified disorders of the circulatory system	0.000	0.888	0.112
K83.5 Biliary cyst	0.111	0.889	0.000
K83.4 Spasm of sphincter of Oddi	0.111	0.889	0.000
K83.2 Perforation of bile duct	0.111	0.889	0.000
I09 Other rheumatic heart diseases	0.000	0.892	0.108
I06 Rheumatic aortic valve diseases	0.000	0.893	0.106
I21.4 Acute subendocardial myocardial infarction	0.000	0.895	0.105
I32.8 Pericarditis in other diseases classified elsewhere	0.000	0.895	0.105
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere	0.000	0.895	0.105
I32.0 Pericarditis in bacterial diseases classified elsewhere	0.000	0.895	0.105
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere	0.000	0.895	0.105
I39.4 Multiple valve disorders in diseases classified elsewhere	0.000	0.895	0.105
I39.3 Pulmonary valve disorders in diseases classified elsewhere	0.000	0.895	0.105
I39.2 Tricuspid valve disorders in diseases classified elsewhere	0.000	0.895	0.105
I39.1 Aortic valve disorders in diseases classified elsewhere	0.000	0.895	0.105
I39.0 Mitral valve disorders in diseases classified elsewhere	0.000	0.895	0.105
I41.8 Myocarditis in other diseases classified elsewhere	0.000	0.895	0.105
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere	0.000	0.895	0.105
I41.1 Myocarditis in viral diseases classified elsewhere	0.000	0.895	0.105
I41.0 Myocarditis in bacterial diseases classified elsewhere	0.000	0.895	0.105
I48.9 Atrial fibrillation and atrial flutter, unspecified	0.000	0.895	0.105
I48.4 Atypical atrial flutter	0.000	0.895	0.105
I48.3 Typical atrial flutter	0.000	0.895	0.105
I48.2 Chronic atrial fibrillation	0.000	0.895	0.105
I48.1 Persistent atrial fibrillation	0.000	0.895	0.105
I48.0 Paroxysmal atrial fibrillation	0.000	0.895	0.105
I52.8 Other heart disorders in other diseases classified elsewhere	0.000	0.895	0.105
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere	0.000	0.895	0.105
I52.0 Other heart disorders in bacterial diseases classified elsewhere	0.000	0.895	0.105
I51.5 Myocardial degeneration	0.000	0.898	0.102
I51.2 Rupture of papillary muscle, not elsewhere classified	0.000	0.898	0.102
I30.8 Other forms of acute pericarditis	0.000	0.898	0.101
I30.0 Acute nonspecific idiopathic pericarditis	0.000	0.898	0.101
I08 Multiple valve diseases	0.000	0.900	0.100
I43.8 Cardiomyopathy in other diseases classified elsewhere	0.000	0.900	0.100
I43.2 Cardiomyopathy in nutritional diseases	0.000	0.900	0.100
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere	0.000	0.900	0.100
I51.3 Intracardiac thrombosis, not elsewhere classified	0.000	0.901	0.099
I99 Other and unspecified disorders of circulatory system	0.000	0.902	0.098
I40.9 Acute myocarditis, unspecified	0.000	0.903	0.096
I40.8 Other acute myocarditis	0.000	0.903	0.096
I40.1 Isolated myocarditis	0.000	0.903	0.096
K85.9 Acute pancreatitis, unspecified	0.095	0.905	0.000
I07.9 Tricuspid valve disease, unspecified	0.000	0.906	0.094
I07.8 Other tricuspid valve diseases	0.000	0.906	0.094
I07.2 Tricuspid stenosis with insufficiency	0.000	0.906	0.094
I07.0 Tricuspid stenosis	0.000	0.906	0.094
I36.9 Nonrheumatic tricuspid valve disorder, unspecified	0.000	0.906	0.094
I36.8 Other nonrheumatic tricuspid valve disorders	0.000	0.906	0.094
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency	0.000	0.906	0.094
I36.0 Nonrheumatic tricuspid (valve) stenosis	0.000	0.906	0.094
I02 Rheumatic chorea	0.000	0.906	0.094
I01 Rheumatic fever with heart involvement	0.000	0.906	0.094
I43.1 Cardiomyopathy in metabolic diseases	0.000	0.907	0.093
I00 Rheumatic fever without mention of heart involvement	0.000	0.908	0.092
I08.1 Disorders of both mitral and tricuspid valves	0.000	0.909	0.091
I05 Rheumatic mitral valve diseases	0.000	0.910	0.090
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.000	0.910	0.090
I51.6 Cardiovascular disease, unspecified	0.000	0.910	0.090
I33.9 Acute endocarditis, unspecified	0.000	0.910	0.089
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.000	0.912	0.088
K83.9 Disease of biliary tract, unspecified	0.088	0.912	0.000
I46.9 Cardiac arrest, unspecified	0.000	0.913	0.087
I40.0 Infective myocarditis	0.000	0.915	0.085
I46.1 Sudden cardiac death, so described	0.000	0.918	0.082
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.000	0.919	0.081
K83.1 Obstruction of bile duct	0.081	0.919	0.000
I09.9 Rheumatic heart disease, unspecified	0.000	0.920	0.079
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.000	0.921	0.079
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.000	0.921	0.078
I09.8 Other specified rheumatic heart diseases	0.000	0.922	0.078
I09.2 Chronic rheumatic pericarditis	0.000	0.922	0.078
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.000	0.922	0.078
I09.0 Rheumatic myocarditis	0.000	0.922	0.078
I06.9 Rheumatic aortic valve disease, unspecified	0.000	0.923	0.076
I06.8 Other rheumatic aortic valve diseases	0.000	0.923	0.076
I06.2 Rheumatic aortic stenosis with insufficiency	0.000	0.923	0.076
I06.1 Rheumatic aortic insufficiency	0.000	0.923	0.076
I06.0 Rheumatic aortic stenosis	0.000	0.923	0.076
I98 Other disorders of circulatory system in diseases classified elsewhere	0.000	0.927	0.073
I30.9 Acute pericarditis, unspecified	0.000	0.928	0.072
I08.9 Multiple valve disease, unspecified	0.000	0.928	0.072
I47 Paroxysmal tachycardia	0.000	0.929	0.071
K83.8 Other specified diseases of biliary tract	0.071	0.929	0.000
Z95 Presence of cardiac and vascular implants and grafts	0.000	0.930	0.070
Z95.8 Presence of other cardiac and vascular implants and grafts	0.000	0.931	0.069
I01.9 Acute rheumatic heart disease, unspecified	0.000	0.932	0.067
I01.8 Other acute rheumatic heart disease	0.000	0.932	0.067
I01.2 Acute rheumatic myocarditis	0.000	0.932	0.067
I01.1 Acute rheumatic endocarditis	0.000	0.932	0.067
I01.0 Acute rheumatic pericarditis	0.000	0.932	0.067
I02.9 Rheumatic chorea without heart involvement	0.000	0.932	0.067
I02.0 Rheumatic chorea with heart involvement	0.000	0.932	0.067
I21.0 Acute transmural myocardial infarction of anterior wall	0.000	0.932	0.068
I05.9 Mitral valve disease, unspecified	0.000	0.932	0.067
I05.0 Mitral stenosis	0.000	0.935	0.065
I05.8 Other mitral valve diseases	0.000	0.935	0.065
I10-I15 Hypertensive diseases	0.000	0.936	0.064
K83.0 Cholangitis	0.064	0.936	0.000
I97.2 Postmastectomy lymphoedema syndrome	0.000	0.937	0.063
I44 Atrioventricular and left bundle-branch block	0.000	0.938	0.062
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.001	0.939	0.061
I27 Other pulmonary heart diseases	0.000	0.940	0.060
I97.9 Postprocedural disorder of circulatory system, unspecified	0.000	0.942	0.058
I97.0 Postcardiotomy syndrome	0.000	0.942	0.058
I08.0 Disorders of both mitral and aortic valves	0.000	0.942	0.058
I47.0 Reentry ventricular arrhythmia	0.000	0.942	0.058
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.000	0.942	0.058
I28 Other diseases of pulmonary vessels	0.000	0.943	0.057
I05.1 Rheumatic mitral insufficiency	0.000	0.943	0.056
I05.2 Mitral stenosis with insufficiency	0.000	0.945	0.055
I51.4 Myocarditis, unspecified	0.001	0.945	0.054
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.000	0.945	0.055
I97.1 Other functional disturbances following cardiac surgery	0.000	0.947	0.053
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.000	0.947	0.053
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.000	0.947	0.053
I98.0 Cardiovascular syphilis	0.000	0.947	0.053
I51.9 Heart disease, unspecified	0.000	0.948	0.052
I11 Hypertensive heart disease	0.000	0.952	0.048
Z95.4 Presence of other heart-valve replacement	0.000	0.952	0.048
I44.4 Left anterior fascicular block	0.000	0.953	0.047
I47.9 Paroxysmal tachycardia, unspecified	0.000	0.953	0.047
I44.1 Atrioventricular block, second degree	0.000	0.953	0.047
Z95.3 Presence of xenogenic heart valve	0.000	0.954	0.046
I15 Secondary hypertension	0.000	0.954	0.046
I13 Hypertensive heart and renal disease	0.000	0.954	0.046
I26 Pulmonary embolism	0.000	0.954	0.046
I27.9 Pulmonary heart disease, unspecified	0.000	0.955	0.045
I44.5 Left posterior fascicular block	0.000	0.955	0.045
I08.8 Other multiple valve diseases	0.000	0.956	0.043
I45 Other conduction disorders	0.000	0.956	0.044
I27.8 Other specified pulmonary heart diseases	0.000	0.957	0.043
I27.1 Kyphoscoliotic heart disease	0.000	0.957	0.043
I98.2 Oesophageal varices in diseases classified elsewhere	0.000	0.958	0.042
I27.2 Other secondary pulmonary hypertension	0.000	0.958	0.042
I28.9 Disease of pulmonary vessels, unspecified	0.000	0.959	0.041
I28.1 Aneurysm of pulmonary artery	0.000	0.959	0.041
I28.0 Arteriovenous fistula of pulmonary vessels	0.000	0.959	0.041
I46.0 Cardiac arrest with successful resuscitation	0.000	0.960	0.040
I11.9 Hypertensive heart disease without (congestive) heart failure	0.000	0.960	0.040
I44.6 Other and unspecified fascicular block	0.000	0.960	0.040
I15.9 Seconday hypertension, unspecified	0.000	0.961	0.039
I44.7 Left bundle-branch block, unspecified	0.000	0.961	0.039
I70-I79 Diseases of arteries, arterioles and capillaries	0.000	0.962	0.038
I27.0 Primary pulmonary hypertension	0.000	0.964	0.036
I77 Other disorders of arteries and arterioles	0.000	0.964	0.036
I50 Heart failure	0.000	0.964	0.036
I12 Hypertensive renal disease	0.000	0.964	0.035
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.000	0.965	0.034
I44.0 Atrioventricular block, first degree	0.000	0.966	0.034
I77.9 Disorder of arteries and arterioles, unspecified	0.000	0.966	0.034
I28.8 Other specified diseases of pulmonary vessels	0.000	0.966	0.033
I15.8 Other secondary hypertension	0.000	0.966	0.033
I15.2 Hypertension secondary to endocrine disorders	0.000	0.966	0.033
I13.9 Hypertensive heart and renal disease, unspecified	0.000	0.967	0.033
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.000	0.967	0.033
I13.1 Hypertensive heart and renal disease with renal failure	0.000	0.967	0.033
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.000	0.967	0.033
I44.3 Other and unspecified atrioventricular block	0.000	0.967	0.033
I45.9 Conduction disorder, unspecified	0.000	0.968	0.032
I77.1 Stricture of artery	0.000	0.968	0.032
I44.2 Atrioventricular block, complete	0.000	0.968	0.032
I15.0 Renovascular hypertension	0.000	0.968	0.032
I45.4 Nonspecific intraventricular block	0.000	0.968	0.031
I45.0 Right fascicular block	0.000	0.968	0.031
I11.0 Hypertensive heart disease with (congestive) heart failure	0.000	0.970	0.030
I45.6 Preexcitation syndrome	0.000	0.970	0.030
K58.9 Irritable bowel syndrome without diarrhoea	0.029	0.971	0.000
I72 Other aneurysm	0.000	0.971	0.029
I45.3 Trifascicular block	0.000	0.972	0.028
I45.8 Other specified conduction disorders	0.000	0.972	0.028
E70-E90 Metabolic disorders	0.000	0.973	0.027
I47.2 Ventricular tachycardia	0.000	0.973	0.027
I15.1 Hypertension secondary to other renal disorders	0.000	0.973	0.027
E83.4 Disorders of magnesium metabolism	0.000	0.973	0.027
I45.5 Other specified heart block	0.000	0.973	0.027
I08.2 Disorders of both aortic and tricuspid valves	0.002	0.974	0.024
E83 Disorders of mineral metabolism	0.000	0.974	0.026
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.974	0.026
I34 Nonrheumatic mitral valve disorders	0.000	0.974	0.026
I77.5 Necrosis of artery	0.000	0.974	0.026
I77.4 Coeliac artery compression syndrome	0.000	0.974	0.026
I77.3 Arterial fibromuscular dysplasia	0.000	0.974	0.026
K86 Other diseases of pancreas	0.024	0.974	0.002
I77.6 Arteritis, unspecified	0.000	0.975	0.025
I12.0 Hypertensive renal disease with renal failure	0.000	0.975	0.025
I72.8 Aneurysm of other specified arteries	0.000	0.975	0.025
I77.0 Arteriovenous fistula, acquired	0.000	0.975	0.024
I50.0 Congestive heart failure	0.000	0.976	0.024
Z95.2 Presence of prosthetic heart valve	0.000	0.976	0.024
I77.8 Other specified disorders of arteries and arterioles	0.000	0.976	0.023
I74 Arterial embolism and thrombosis	0.000	0.977	0.023
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.000	0.978	0.022
I45.2 Bifascicular block	0.000	0.979	0.021
I72.0 Aneurysm of carotid artery	0.000	0.979	0.021
I70 Atherosclerosis	0.000	0.979	0.021
I72.9 Aneurysm of unspecified site	0.000	0.979	0.021
E83.5 Disorders of calcium metabolism	0.000	0.979	0.021
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.000	0.979	0.021
I72.4 Aneurysm of artery of lower extremity	0.000	0.979	0.021
I72.6 Aneurysm and dissection of vertebral artery	0.000	0.979	0.021
I72.5 Aneurysm and dissection of other precerebral arteries	0.000	0.979	0.021
I72.1 Aneurysm of artery of upper extremity	0.000	0.979	0.021
I72.2 Aneurysm of renal artery	0.000	0.980	0.020
I74.5 Embolism and thrombosis of iliac artery	0.000	0.980	0.020
I77.2 Rupture of artery	0.000	0.980	0.020
E83.3 Disorders of phosphorus metabolism	0.000	0.980	0.020
E84 Cystic fibrosis	0.000	0.980	0.020
E77 Disorders of glycoprotein metabolism	0.000	0.980	0.020
E76 Disorders of glycosaminoglycan metabolism	0.000	0.980	0.020
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.000	0.980	0.020
E72 Other disorders of amino-acid metabolism	0.000	0.980	0.020
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.000	0.980	0.020
E70 Disorders of aromatic amino-acid metabolism	0.000	0.980	0.020
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.000	0.980	0.020
K86.9 Disease of pancreas, unspecified	0.019	0.980	0.001
E89.2 Postprocedural hypoparathyroidism	0.000	0.980	0.020
E79 Disorders of purine and pyrimidine metabolism	0.000	0.981	0.019
E83.9 Disorder of mineral metabolism, unspecified	0.000	0.981	0.019
E83.8 Other disorders of mineral metabolism	0.000	0.981	0.019
E83.2 Disorders of zinc metabolism	0.000	0.981	0.019
E83.0 Disorders of copper metabolism	0.000	0.981	0.019
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.981	0.019
I79.1 Aortitis in diseases classified elsewhere	0.000	0.981	0.019
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.000	0.981	0.019
I95 Hypotension	0.000	0.981	0.019
E88 Other metabolic disorders	0.000	0.981	0.019
I34.8 Other nonrheumatic mitral valve disorders	0.000	0.982	0.018
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.000	0.982	0.018
I51.8 Other ill-defined heart diseases	0.000	0.982	0.018
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.000	0.982	0.017
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.000	0.983	0.017
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.000	0.983	0.017
I74.0 Embolism and thrombosis of abdominal aorta	0.000	0.983	0.017
I45.1 Other and unspecified right bundle-branch block	0.000	0.983	0.017
I47.1 Supraventricular tachycardia	0.000	0.983	0.017
I74.9 Embolism and thrombosis of unspecified artery	0.000	0.983	0.017
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.000	0.984	0.016
E74 Other disorders of carbohydrate metabolism	0.000	0.984	0.016
I60-I69 Cerebrovascular diseases	0.000	0.984	0.016
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.000	0.984	0.016
E89.8 Other postprocedural endocrine and metabolic disorders	0.000	0.984	0.016
E89.5 Postprocedural testicular hypofunction	0.000	0.984	0.016
E89.4 Postprocedural ovarian failure	0.000	0.984	0.016
E89.1 Postprocedural hypoinsulinaemia	0.000	0.984	0.016
I12.9 Hypertensive renal disease without renal failure	0.000	0.984	0.016
I70.0 Atherosclerosis of aorta	0.000	0.984	0.016
E88.2 Lipomatosis, not elsewhere classified	0.000	0.984	0.016
I70.9 Generalised and unspecified atherosclerosis	0.000	0.985	0.015
I70.8 Atherosclerosis of other arteries	0.000	0.985	0.015
E89.3 Postprocedural hypopituitarism	0.000	0.985	0.015
I95.0 Idiopathic hypotension	0.000	0.985	0.015
E73 Lactose intolerance	0.000	0.985	0.015
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.000	0.985	0.015
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.000	0.985	0.014
E70.8 Other disorders of aromatic amino-acid metabolism	0.000	0.985	0.014
E70.3 Albinism	0.000	0.985	0.014
E70.2 Disorders of tyrosine metabolism	0.000	0.985	0.014
E70.1 Other hyperphenylalaninaemias	0.000	0.985	0.014
E70.0 Classical phenylketonuria	0.000	0.985	0.014
E71.3 Disorders of fatty-acid metabolism	0.000	0.985	0.014
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.000	0.985	0.014
E71.1 Other disorders of branched-chain amino-acid metabolism	0.000	0.985	0.014
E71.0 Maple-syrup-urine disease	0.000	0.985	0.014
E72.9 Disorder of amino-acid metabolism, unspecified	0.000	0.985	0.014
E72.8 Other specified disorders of amino-acid metabolism	0.000	0.985	0.014
E72.5 Disorders of glycine metabolism	0.000	0.985	0.014
E72.4 Disorders of ornithine metabolism	0.000	0.985	0.014
E72.3 Disorders of lysine and hydroxylysine metabolism	0.000	0.985	0.014
E72.2 Disorders of urea cycle metabolism	0.000	0.985	0.014
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.000	0.985	0.014
E72.0 Disorders of amino-acid transport	0.000	0.985	0.014
E75.6 Lipid storage disorder, unspecified	0.000	0.985	0.014
E75.5 Other lipid storage disorders	0.000	0.985	0.014
E75.4 Neuronal ceroid lipofuscinosis	0.000	0.985	0.014
E75.3 Sphingolipidosis, unspecified	0.000	0.985	0.014
E75.2 Other sphingolipidosis	0.000	0.985	0.014
E75.1 Other gangliosidosis	0.000	0.985	0.014
E75.0 GM2 gangliosidosis	0.000	0.985	0.014
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.000	0.985	0.014
E76.8 Other disorders of glucosaminoglycan metabolism	0.000	0.985	0.014
E76.3 Mucopolysaccharidosis, unspecified	0.000	0.985	0.014
E76.2 Other mucopolysaccharidoses	0.000	0.985	0.014
E76.1 Mucopolysaccharidosis, type II	0.000	0.985	0.014
E76.0 Mucopolysaccharidosis, type I	0.000	0.985	0.014
E77.9 Disorder of glycoprotein metabolism, unspecified	0.000	0.985	0.014
E77.8 Other disorders of glycoprotein metabolism	0.000	0.985	0.014
E77.1 Defects in glycoprotein degradation	0.000	0.985	0.014
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.000	0.985	0.014
E84.9 Cystic fibrosis, unspecified	0.000	0.985	0.014
E84.8 Cystic fibrosis with other manifestations	0.000	0.985	0.014
E84.1 Cystic fibrosis with intestinal manifestations	0.000	0.985	0.014
E84.0 Cystic fibrosis with pulmonary manifestations	0.000	0.985	0.014
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.000	0.985	0.014
I72.3 Aneurysm of iliac artery	0.000	0.986	0.014
I65.2 Occlusion and stenosis of carotid artery	0.000	0.986	0.014
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.000	0.986	0.014
E79.8 Other disorders of purine and pyrimidine metabolism	0.000	0.986	0.014
E79.1 Lesch-Nyhan syndrome	0.000	0.986	0.014
E88.9 Metabolic disorder, unspecified	0.000	0.986	0.014
E85 Amyloidosis	0.000	0.986	0.013
E88.8 Other specified metabolic disorders	0.000	0.987	0.013
I95.8 Other hypotension	0.000	0.987	0.013
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.000	0.987	0.013
I70.1 Atherosclerosis of renal artery	0.000	0.987	0.013
E88.1 Lipodystrophy, not elsewhere classified	0.000	0.987	0.013
I34.2 Nonrheumatic mitral (valve) stenosis	0.000	0.987	0.013
E88.3 Tumour lysis syndrome	0.000	0.987	0.013
I34.1 Mitral (valve) prolapse	0.000	0.987	0.013
I61 Intracerebral haemorrhage	0.000	0.987	0.013
K86.1 Other chronic pancreatitis	0.012	0.988	0.001
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.000	0.988	0.012
I70.2 Atherosclerosis of arteries of the extremities	0.000	0.988	0.012
K66.0 Peritoneal adhesions	0.012	0.988	0.000
E74.9 Disorder of carbohydrate metabolism, unspecified	0.000	0.988	0.011
E74.8 Other specified disorders of carbohydrate metabolism	0.000	0.988	0.011
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.000	0.988	0.011
E74.2 Disorders of galactose metabolism	0.000	0.988	0.011
E74.1 Disorders of fructose metabolism	0.000	0.988	0.011
E74.0 Glycogen storage disease	0.000	0.988	0.011
I70.00 Atherosclerosis of aorta (without gangrene)	0.000	0.988	0.012
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.000	0.988	0.012
E80 Disorders of porphyrin and bilirubin metabolism	0.000	0.988	0.011
I70.01 Atherosclerosis of aorta (with gangrene)	0.000	0.988	0.011
K86.0 Alcohol-induced chronic pancreatitis	0.010	0.989	0.002
I70.81 Atherosclerosis of other arteries (with gangrene)	0.000	0.989	0.011
I70.80 Atherosclerosis of other arteries (without gangrene)	0.000	0.989	0.011
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.000	0.989	0.011
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.000	0.989	0.011
I49 Other cardiac arrhythmias	0.000	0.989	0.011
I95.2 Hypotension due to drugs	0.000	0.989	0.011
J06.9 Acute upper respiratory infection, unspecified	0.000	0.989	0.011
I74.8 Embolism and thrombosis of other arteries	0.000	0.989	0.011
E73.8 Other lactose intolerance	0.000	0.989	0.011
E73.1 Secondary lactase deficiency	0.000	0.989	0.011
E73.0 Congenital lactase deficiency	0.000	0.989	0.011
I68 Cerebrovascular disorders in diseases classified elsewhere	0.000	0.989	0.011
I61.5 Intracerebral haemorrhage, intraventricular	0.000	0.989	0.011
I78 Diseases of capillaries	0.000	0.989	0.011
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.000	0.989	0.011
I65.8 Occlusion and stenosis of other precerebral artery	0.000	0.989	0.011
I65.1 Occlusion and stenosis of basilar artery	0.000	0.989	0.011
I62 Other nontraumatic intracranial haemorrhage	0.000	0.989	0.011
I65.0 Occlusion and stenosis of vertebral artery	0.000	0.989	0.010
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.000	0.990	0.010
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.000	0.990	0.010
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.000	0.990	0.010
Z90.4 Acquired absence of other parts of digestive tract	0.010	0.990	0.000
I61.3 Intracerebral haemorrhage in brain stem	0.000	0.990	0.010
E85.8 Other amyloidosis	0.000	0.990	0.010
E85.2 Heredofamilial amyloidosis, unspecified	0.000	0.990	0.010
E85.1 Neuropathic heredofamilial amyloidosis	0.000	0.990	0.010
E85.0 Nonneuropathic heredofamilial amyloidosis	0.000	0.990	0.010
Z95.0 Presence of cardiac pacemaker	0.000	0.990	0.010
I61.4 Intracerebral haemorrhage in cerebellum	0.000	0.990	0.010
I70.11 Atherosclerosis of renal artery (with gangrene)	0.000	0.990	0.009
I71 Aortic aneurysm and dissection	0.000	0.991	0.009
I69 Sequelae of cerebrovascular disease	0.000	0.991	0.009
I49.3 Ventricular premature depolarisation	0.000	0.991	0.009
I61.6 Intracerebral haemorrhage, multiple localised	0.000	0.991	0.009
E85.3 Secondary systemic amyloidosis	0.000	0.991	0.009
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.000	0.991	0.009

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations