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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

Affx-52341719
log Bayes Factor = 201.372
Chromosome 6   position 32,552,146  (GRCh37) Explore Affx-52341719 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
H36.0 Diabetic retinopathy
0.000 0.000 1.000
J45.9 Asthma, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
J40-J47 Chronic lower respiratory diseases
0.000 0.000 1.000
Chapter XI Diseases of the digestive system
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
M05-M14 Inflammatory polyarthropathies
0.000 0.000 1.000
E16.2 Hypoglycaemia, unspecified
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
# Top node
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
E16 Other disorders of pancreatic internal secretion
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.000 1.000
J45 Asthma
0.000 0.000 1.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.000 1.000
M05 Seropositive rheumatoid arthritis
0.000 0.000 1.000
K51.9 Ulcerative colitis, unspecified
1.000 0.000 0.000
J44 Other chronic obstructive pulmonary disease
0.000 0.000 1.000
Chapter X Diseases of the respiratory system
0.000 0.001 0.999
H36 Retinal disorders in diseases classified elsewhere
0.000 0.001 0.999
K51 Ulcerative colitis
0.999 0.001 0.000
E10.4 With neurological complications
0.000 0.001 0.999
K90 Intestinal malabsorption
0.000 0.001 0.999
K90-K93 Other diseases of the digestive system
0.000 0.001 0.999
Chapter VII Diseases of the eye and adnexa
0.000 0.001 0.999
H30-H36 Disorders of choroid and retina
0.000 0.001 0.999
E14.9 Without complications
0.000 0.002 0.998
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.002 0.998
G35-G37 Demyelinating diseases of the central nervous system
0.997 0.002 0.000
G37 Other demyelinating diseases of central nervous system
0.997 0.003 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.003 0.997
G37.9 Demyelinating disease of central nervous system, unspecified
0.996 0.004 0.000
E14.3 With ophthalmic complications
0.000 0.004 0.996
K70-K77 Diseases of liver
0.000 0.004 0.996
K50-K52 Noninfective enteritis and colitis
0.001 0.006 0.993
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.000 0.006 0.994
E83.1 Disorders of iron metabolism
0.994 0.006 0.000
K55-K64 Other diseases of intestines
0.000 0.007 0.993
K51.3 Ulcerative (chronic) rectosigmoiditis
0.991 0.009 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.010 0.990
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.012 0.988
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.000 0.014 0.986
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.016 0.984
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.017 0.983
H40-H42 Glaucoma
0.000 0.017 0.983
K74 Fibrosis and cirrhosis of liver
0.000 0.017 0.983
K82 Other diseases of gallbladder
0.000 0.020 0.980
E10.5 With peripheral circulatory complications
0.000 0.022 0.978
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.023 0.977
K50 Crohn's disease [regional enteritis]
0.000 0.026 0.974
E11.3 With ophthalmic complications
0.000 0.027 0.973
K82.8 Other specified diseases of gallbladder
0.000 0.028 0.972
H40 Glaucoma
0.000 0.029 0.971
H43-H45 Disorders of vitreous body and globe
0.000 0.030 0.970
J33.9 Nasal polyp, unspecified
0.000 0.031 0.969
K60 Fissure and fistula of anal and rectal regions
0.000 0.032 0.968
J33 Nasal polyp
0.000 0.033 0.967
H40.9 Glaucoma, unspecified
0.000 0.033 0.967
K74.3 Primary biliary cirrhosis
0.000 0.034 0.966
E05.9 Thyrotoxicosis, unspecified
0.000 0.035 0.965
E11.1 With ketoacidosis
0.000 0.037 0.963
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.043 0.957
H43 Disorders of vitreous body
0.000 0.044 0.956
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.045 0.955
K63 Other diseases of intestine
0.000 0.045 0.955
E06 Thyroiditis
0.000 0.046 0.954
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.046 0.954
J43 Emphysema
0.000 0.047 0.953
K51.8 Other ulcerative colitis
0.950 0.050 0.000
J30-J39 Other diseases of upper respiratory tract
0.000 0.053 0.947
J46 Status asthmaticus
0.000 0.055 0.945
K58 Irritable bowel syndrome
0.000 0.056 0.944
H34 Retinal vascular occlusions
0.000 0.059 0.941
K63.9 Disease of intestine, unspecified
0.000 0.060 0.940
E10.2 With renal complications
0.000 0.064 0.936
K72 Hepatic failure, not elsewhere classified
0.000 0.065 0.935
K52 Other non-infective gastro-enteritis and colitis
0.000 0.066 0.933
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.068 0.932
J33.8 Other polyp of sinus
0.000 0.070 0.930
H43.3 Other vitreous opacities
0.000 0.070 0.930
K58.0 Irritable bowel syndrome with diarrhoea
0.000 0.071 0.929
J86 Pyothorax
0.000 0.072 0.928
E06.3 Autoimmune thyroiditis
0.000 0.077 0.923
K75 Other inflammatory liver diseases
0.000 0.077 0.923
K86 Other diseases of pancreas
0.000 0.078 0.922
K60.0 Acute anal fissure
0.000 0.083 0.917
K55 Vascular disorders of intestine
0.000 0.084 0.916
M07 Psoriatic and enteropathic arthropathies
0.000 0.085 0.914
M65-M68 Disorders of synovium and tendon
0.000 0.090 0.910
J43.9 Emphysema, unspecified
0.000 0.090 0.910
K60.2 Anal fissure, unspecified
0.000 0.094 0.906
K50.1 Crohn's disease of large intestine
0.000 0.095 0.905
K63.3 Ulcer of intestine
0.000 0.097 0.903
M06.0 Seronegative rheumatoid arthritis
0.000 0.100 0.900
E11.5 With peripheral circulatory complications
0.000 0.103 0.897
K75.4 Autoimmune hepatitis
0.000 0.105 0.895
L40-L45 Papulosquamous disorders
0.000 0.105 0.895
J44.9 Chronic obstructive pulmonary disease, unspecified
0.000 0.105 0.895
E03.8 Other specified hypothyroidism
0.000 0.106 0.894
E07 Other disorders of thyroid
0.000 0.107 0.893
L43 Lichen planus
0.000 0.107 0.893
L43.9 Lichen planus, unspecified
0.000 0.109 0.891
H40.1 Primary open-angle glaucoma
0.000 0.110 0.890
K62 Other diseases of anus and rectum
0.000 0.110 0.890
L40 Psoriasis
0.000 0.114 0.886
J86.9 Pyothorax without fistula
0.000 0.115 0.885
L40.5 Arthropathic psoriasis
0.000 0.122 0.878
K82.1 Hydrops of gallbladder
0.000 0.127 0.873
E13 Other specified diabetes mellitus
0.000 0.128 0.872
K50.8 Other Crohn's disease
0.000 0.128 0.872
E11.6 With other specified complications
0.000 0.128 0.872
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.131 0.869
K74.5 Biliary cirrhosis, unspecified
0.000 0.131 0.869
K86.2 Cyst of pancreas
0.000 0.133 0.867
M65 Synovitis and tenosynovitis
0.000 0.133 0.867
K62.4 Stenosis of anus and rectum
0.000 0.134 0.866
K55.2 Angiodysplasia of colon
0.000 0.134 0.866
H34.8 Other retinal vascular occlusions
0.000 0.137 0.863
K60.5 Anorectal fistula
0.000 0.137 0.863
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.139 0.861
E78.0 Pure hypercholesterolaemia
0.000 0.143 0.857
K52.9 Non-infective gastro-enteritis and colitis, unspecified
0.000 0.146 0.854
K72.9 Hepatic failure, unspecified
0.000 0.147 0.853
M07.3 Other psoriatic arthropathies
0.000 0.147 0.853
E11.2 With renal complications
0.000 0.147 0.853
Chapter IX Diseases of the circulatory system
0.000 0.151 0.849
M06.3 Rheumatoid nodule
0.000 0.154 0.846
I20-I25 Ischaemic heart diseases
0.000 0.154 0.846
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.154 0.845
E70-E90 Metabolic disorders
0.001 0.155 0.844
K52.1 Toxic gastro-enteritis and colitis
0.000 0.155 0.845
I10-I15 Hypertensive diseases
0.000 0.158 0.842
K62.1 Rectal polyp
0.000 0.160 0.840
K51.4 Pseudopolyposis of colon
0.839 0.161 0.000
M06.4 Inflammatory polyarthropathy
0.000 0.165 0.835
E07.9 Disorder of thyroid, unspecified
0.000 0.165 0.835
H43.8 Other disorders of vitreous body
0.000 0.166 0.834
H25-H28 Disorders of lens
0.000 0.168 0.832
M65.4 Radial styloid tenosynovitis [de Quervain]
0.000 0.173 0.827
I22 Subsequent myocardial infarction
0.000 0.174 0.826
K73 Chronic hepatitis, not elsewhere classified
0.000 0.176 0.824
K51.2 Ulcerative (chronic) proctitis
0.824 0.176 0.000
G37.8 Other specified demyelinating diseases of central nervous system
0.824 0.176 0.000
J86.0 Pyothorax with fistula
0.000 0.180 0.820
H40.5 Glaucoma secondary to other eye disorders
0.000 0.180 0.820
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.185 0.815
K51.5 Mucosal proctocolitis
0.813 0.187 0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.812 0.188 0.000
J95-J99 Other diseases of the respiratory system
0.000 0.189 0.811
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.190 0.810
K63.4 Enteroptosis
0.000 0.191 0.809
K86.1 Other chronic pancreatitis
0.000 0.193 0.807
K81 Cholecystitis
0.000 0.195 0.805
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.196 0.804
I20 Angina pectoris
0.000 0.197 0.803
I12 Hypertensive renal disease
0.000 0.202 0.798
K72.0 Acute and subacute hepatic failure
0.000 0.204 0.796
K55.8 Other vascular disorders of intestine
0.000 0.204 0.796
E16.1 Other hypoglycaemia
0.000 0.207 0.793
J33.0 Polyp of nasal cavity
0.000 0.207 0.793
K50.0 Crohn's disease of small intestine
0.000 0.210 0.790
I10 Essential (primary) hypertension
0.000 0.210 0.790
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.212 0.788
M14 Arthropathies in other diseases classified elsewhere
0.000 0.213 0.787
H27 Other disorders of lens
0.000 0.218 0.782
E13.9 Without complications
0.000 0.219 0.781
E40-E46 Malnutrition
0.000 0.224 0.776
M65.9 Synovitis and tenosynovitis, unspecified
0.000 0.224 0.776
H34.2 Other retinal artery occlusions
0.000 0.225 0.775
K90.9 Intestinal malabsorption, unspecified
0.000 0.226 0.773
I24 Other acute ischaemic heart diseases
0.000 0.233 0.767
K52.8 Other specified non-infective gastro-enteritis and colitis
0.000 0.240 0.760
I20.1 Angina pectoris with documented spasm
0.000 0.240 0.760
K82.9 Disease of gallbladder, unspecified
0.000 0.242 0.758
K62.7 Radiation proctitis
0.000 0.242 0.758
E11.0 With coma
0.000 0.243 0.757
L40.9 Psoriasis, unspecified
0.000 0.244 0.756
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)
0.000 0.247 0.753
K50.9 Crohn's disease, unspecified
0.000 0.254 0.746
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.254 0.746
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.254 0.746
K81.1 Chronic cholecystitis
0.000 0.255 0.745
K82.2 Perforation of gallbladder
0.000 0.259 0.741
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.260 0.740
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.260 0.740
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)
0.000 0.261 0.739
J43.2 Centrilobular emphysema
0.000 0.263 0.737
H43.2 Crystalline deposits in vitreous body
0.000 0.269 0.731
J98 Other respiratory disorders
0.000 0.270 0.730
K82.3 Fistula of gallbladder
0.000 0.272 0.728
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.273 0.727
I12.9 Hypertensive renal disease without renal failure
0.000 0.274 0.726
H34.1 Central retinal artery occlusion
0.000 0.275 0.725
H40.4 Glaucoma secondary to eye inflammation
0.000 0.276 0.724
I15 Secondary hypertension
0.000 0.276 0.724
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.276 0.724
H43.9 Disorder of vitreous body, unspecified
0.000 0.277 0.722
M70-M79 Other soft tissue disorders
0.000 0.278 0.722
H30 Chorioretinal inflammation
0.000 0.280 0.720
M11 Other crystal arthropathies
0.000 0.280 0.720
J37 Chronic laryngitis and laryngotracheitis
0.000 0.280 0.720
K74.6 Other and unspecified cirrhosis of liver
0.000 0.281 0.719
M15-M19 Arthrosis
0.000 0.281 0.719
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.282 0.718
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
E10.8 With unspecified complications
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E10.6 With other specified complications
0.000 0.283 0.717
E10.0 With coma
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
M06.8 Other specified rheumatoid arthritis
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E14.8 With unspecified complications
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.6 With other specified complications
0.000 0.283 0.717
E14.5 With peripheral circulatory complications
0.000 0.283 0.717
E14.4 With neurological complications
0.000 0.283 0.717
E14.2 Withrenal complications
0.000 0.283 0.717
E14.1 With ketoacidosis
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.717
M08 Juvenile arthritis
0.000 0.283 0.717
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.283 0.717
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.283 0.717
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.283 0.717
E16.4 Abnormal secretion of gastrin
0.000 0.283 0.717
E16.3 Increased secretion of glucagon
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.717
J45.8 Mixed asthma
0.000 0.283 0.717
J45.1 Nonallergic asthma
0.000 0.283 0.717
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.283 0.717
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.283 0.717
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.283 0.717
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.283 0.717
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.283 0.717
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.283 0.717
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.283 0.717
M05.8 Other seropositive rheumatoid arthritis
0.000 0.283 0.717
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.283 0.717
M05.2 Rheumatoid vasculitis
0.000 0.283 0.717
M05.1 Rheumatoid lung disease
0.000 0.283 0.717
M05.0 Felty's syndrome
0.000 0.283 0.717
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.283 0.716
K51.1 Ulcerative (chronic) ileocolitis
0.716 0.283 0.000
K90.3 Pancreatic steatorrhoea
0.000 0.284 0.716
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.284 0.716
K90.1 Tropical sprue
0.000 0.284 0.716
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.284 0.716
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.284 0.716
G36 Other acute disseminated demyelination
0.715 0.285 0.000
G37.5 Concentric sclerosis [Balo]
0.715 0.285 0.000
G37.4 Subacute necrotising myelitis
0.715 0.285 0.000
G37.2 Central pontine myelinolysis
0.715 0.285 0.000
G37.1 Central demyelination of corpus callosum
0.715 0.285 0.000
G37.0 Diffuse sclerosis
0.715 0.285 0.000
K77 Liver disorders in diseases classified elsewhere
0.000 0.286 0.714
K71 Toxic liver disease
0.000 0.286 0.714
K86.3 Pseudocyst of pancreas
0.000 0.288 0.712
K64 Haemorrhoids and perianal venous thrombosis
0.000 0.288 0.712
K51.0 Ulcerative (chronic) enterocolitis
0.707 0.293 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.000 0.293 0.707
K75.9 Inflammatory liver disease, unspecified
0.000 0.293 0.707
H27.0 Aphakia
0.000 0.293 0.707
E83 Disorders of mineral metabolism
0.647 0.294 0.059
K63.2 Fistula of intestine
0.000 0.295 0.705
I20.9 Angina pectoris, unspecified
0.000 0.295 0.705
H42 Glaucoma in diseases classified elsewhere
0.000 0.295 0.705
K74.4 Secondary biliary cirrhosis
0.000 0.295 0.704
K74.2 Hepatic fibrosis with hepatic sclerosis
0.000 0.295 0.704
K74.1 Hepatic sclerosis
0.000 0.295 0.704
K62.0 Anal polyp
0.000 0.296 0.704
L43.8 Other lichen planus
0.000 0.296 0.704
M06.34 Rheumatoid nodule (Hand)
0.000 0.297 0.703
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.299 0.701
M18 Arthrosis of first carpometacarpal joint
0.000 0.299 0.701
E05.5 Thyroid crisis or storm
0.000 0.300 0.700
E05.4 Thyrotoxicosis factitia
0.000 0.300 0.700
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.300 0.700
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.300 0.700
J41 Simple and mucopurulent chronic bronchitis
0.000 0.300 0.699
H40.6 Glaucoma secondary to drugs
0.000 0.304 0.696
H40.3 Glaucoma secondary to eye trauma
0.000 0.304 0.696
E78.1 Pure hyperglyceridaemia
0.000 0.304 0.696
J98.4 Other disorders of lung
0.000 0.304 0.696
I12.0 Hypertensive renal disease with renal failure
0.000 0.304 0.696
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.000 0.305 0.695
E11.8 With unspecified complications
0.000 0.306 0.693
J33.1 Polypoid sinus degeneration
0.000 0.307 0.693
J32 Chronic sinusitis
0.000 0.307 0.693
K86.0 Alcohol-induced chronic pancreatitis
0.000 0.308 0.692
I20.0 Unstable angina
0.000 0.312 0.688
M14.6 Neuropathic arthropathy
0.000 0.313 0.687
H43.0 Vitreous prolapse
0.000 0.314 0.686
E06.5 Other chronic thyroiditis
0.000 0.316 0.684
E06.4 Drug-induced thyroiditis
0.000 0.316 0.684
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.316 0.684
E06.1 Subacute thyroiditis
0.000 0.316 0.684
E06.0 Acute thyroiditis
0.000 0.316 0.684
M66 Spontaneous rupture of synovium and tendon
0.000 0.316 0.684
J43.8 Other emphysema
0.000 0.317 0.683
J43.1 Panlobular emphysema
0.000 0.317 0.683
J43.0 MacLeod's syndrome
0.000 0.317 0.683
K73.9 Chronic hepatitis, unspecified
0.000 0.319 0.681
K55.1 Chronic vascular disorders of intestine
0.000 0.320 0.680
H34.0 Transient retinal artery occlusion
0.000 0.325 0.675
E06.9 Thyroiditis, unspecified
0.000 0.326 0.674
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.326 0.674
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)
0.000 0.326 0.674
K72.1 Chronic hepatic failure
0.000 0.329 0.671
E88 Other metabolic disorders
0.001 0.331 0.668
M12 Other specific arthropathies
0.000 0.334 0.666
H27.8 Other specified disorders of lens
0.000 0.334 0.666
M65.1 Other infective (teno)synovitis
0.000 0.335 0.665
H34.9 Retinal vascular occlusion, unspecified
0.000 0.335 0.665
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.337 0.663
K52.2 Allergic and dietetic gastro-enteritis and colitis
0.000 0.338 0.662
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.338 0.661
K75.2 Nonspecific reactive hepatitis
0.000 0.338 0.661
K75.1 Phlebitis of portal vein
0.000 0.338 0.661
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.339 0.661
M10 Gout
0.000 0.339 0.661
L40.8 Other psoriasis
0.000 0.340 0.660
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.343 0.657
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.343 0.657
M07.6 Other enteropathic arthropathies
0.000 0.344 0.656
M07.5 Arthropathy in ulcerative colitis
0.000 0.344 0.656
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.344 0.656
M07.2 Psoriatic spondylitis
0.000 0.344 0.656
M07.1 Arthritis mutilans
0.000 0.344 0.656
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.344 0.656
K81.9 Cholecystitis, unspecified
0.000 0.346 0.654
E05.8 Other thyrotoxicosis
0.000 0.347 0.653
H43.1 Vitreous haemorrhage
0.000 0.347 0.653
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.000 0.347 0.653
E78.2 Mixed hyperlipidaemia
0.000 0.347 0.653
H25 Senile cataract
0.000 0.351 0.649
M77 Other enthesopathies
0.000 0.354 0.646
I23 Certain current complications following acute myocardial infarction
0.000 0.354 0.646
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.354 0.646
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.354 0.646
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.354 0.646
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.354 0.646
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.354 0.646
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.354 0.646
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.354 0.646
K62.2 Anal prolapse
0.000 0.354 0.646
K82.0 Obstruction of gallbladder
0.000 0.356 0.644
J60-J70 Lung diseases due to external agents
0.000 0.356 0.644
M15 Polyarthrosis
0.000 0.357 0.643
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.000 0.358 0.642
L44 Other papulosquamous disorders
0.000 0.358 0.642
L41 Parapsoriasis
0.000 0.358 0.642
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.358 0.642
H25.1 Senile nuclear cataract
0.000 0.359 0.641
E07.1 Dyshormogenetic goitre
0.000 0.359 0.640
E07.0 Hypersecretion of calcitonin
0.000 0.359 0.640
L43.3 Subacute (active) lichen planus
0.000 0.360 0.640
L43.2 Lichenoid drug reaction
0.000 0.360 0.640
L43.1 Bullous lichen planus
0.000 0.360 0.640
L43.0 Hypertrophic lichen planus
0.000 0.360 0.640
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.000 0.362 0.638
M65.94 Synovitis and tenosynovitis, unspecified (Hand)
0.000 0.364 0.636
L40.4 Guttate psoriasis
0.000 0.364 0.635
L40.3 Pustulosis palmaris et plantaris
0.000 0.364 0.635
L40.2 Acrodermatitis continua
0.000 0.364 0.635
L40.1 Generalised pustular psoriasis
0.000 0.364 0.635
K86.8 Other specified diseases of pancreas
0.000 0.365 0.635
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.000 0.365 0.635
J42 Unspecified chronic bronchitis
0.000 0.365 0.635
M77.1 Lateral epicondylitis
0.000 0.367 0.633
I15.1 Hypertension secondary to other renal disorders
0.000 0.370 0.630
E13.8 With unspecified complications
0.000 0.375 0.625
E13.7 With multiple complications
0.000 0.375 0.625
E13.6 With other specified complications
0.000 0.375 0.625
E13.5 With peripheral circulatory complications
0.000 0.375 0.625
E13.4 With neurological complications
0.000 0.375 0.625
E13.3 With ophthalmic complications
0.000 0.375 0.625
E13.2 With renal complications
0.000 0.375 0.625
E13.1 With ketoacidosis
0.000 0.375 0.625
E13.0 With coma
0.000 0.375 0.625
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.375 0.625
M77.12 Lateral epicondylitis (Upper arm)
0.000 0.376 0.624
M18.1 Other primary arthrosis of first carpometacarpal joint
0.000 0.377 0.623
M65.2 Calcific tendinitis
0.000 0.378 0.621
M65.0 Abscess of tendon sheath
0.000 0.378 0.621
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)
0.000 0.379 0.621
E74 Other disorders of carbohydrate metabolism
0.001 0.380 0.619
K90.8 Other intestinal malabsorption
0.000 0.380 0.620
E46 Unspecified protein-energy malnutrition
0.000 0.384 0.616
K91.3 Postoperative intestinal obstruction
0.000 0.386 0.614
J98.0 Diseases of bronchus, not elsewhere classified
0.000 0.387 0.613
E80 Disorders of porphyrin and bilirubin metabolism
0.001 0.387 0.612
M07.38 Other psoriatic arthropathies (Other)
0.000 0.388 0.612
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.388 0.612
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.388 0.612
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.388 0.612
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.388 0.612
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.388 0.612
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.388 0.612
I00-I02 Acute rheumatic fever
0.000 0.391 0.609
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.393 0.607
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.393 0.607
M06.38 Rheumatoid nodule (Other)
0.000 0.393 0.607
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.393 0.607
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.393 0.607
M06.33 Rheumatoid nodule (Forearm)
0.000 0.393 0.607
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.393 0.607
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.393 0.607
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.393 0.607
E78.6 Lipoprotein deficiency
0.000 0.394 0.606
E78.3 Hyperchylomicronaemia
0.000 0.394 0.606
E77 Disorders of glycoprotein metabolism
0.001 0.394 0.605
E76 Disorders of glycosaminoglycan metabolism
0.001 0.394 0.605
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.001 0.394 0.605
E72 Other disorders of amino-acid metabolism
0.001 0.394 0.605
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.001 0.394 0.605
E70 Disorders of aromatic amino-acid metabolism
0.001 0.394 0.605
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.001 0.394 0.605
I13 Hypertensive heart and renal disease
0.000 0.396 0.604
J85 Abscess of lung and mediastinum
0.000 0.398 0.602
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.001 0.399 0.601
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)
0.000 0.399 0.601
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral
0.000 0.399 0.601
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.401 0.599
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.401 0.599
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.401 0.599
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.401 0.599
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.401 0.599
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.401 0.599
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.401 0.599
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.401 0.599
L42 Pityriasis rosea
0.000 0.401 0.598
E11.4 With neurological complications
0.000 0.403 0.597
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.000 0.404 0.596
M65.49 Radial styloid tenosynovitis [de Quervain]-Site unspec
0.000 0.407 0.593
M65.48 Radial styloid tenosynovitis [de Quervain]-Other
0.000 0.407 0.593
M65.47 Radial styloid tenosynovitis [de Quervain]-Ankle/foot
0.000 0.407 0.593
M65.46 Radial styloid tenosynovitis [de Quervain]-Lower leg
0.000 0.407 0.593
M65.45 Radial styloid tenosynovitis [de Quervain]-Pelvic/thigh
0.000 0.407 0.593
M65.42 Radial styloid tenosynovitis [de Quervain]-Upper arm
0.000 0.407 0.593
M65.41 Radial styloid tenosynovitis [de Quervain]-Shldr region
0.000 0.407 0.593
M65.40 Radial styloid tenosynovitis [de Quervain] (Multiple sites)
0.000 0.407 0.593
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.409 0.591
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.000 0.409 0.591
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.000 0.409 0.591
K75.8 Other specified inflammatory liver diseases
0.000 0.409 0.591
K60.1 Chronic anal fissure
0.000 0.409 0.591
J98.6 Disorders of diaphragm
0.000 0.414 0.586
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.415 0.585
H27.1 Dislocation of lens
0.000 0.418 0.582
J32.4 Chronic pansinusitis
0.000 0.418 0.582
J96 Respiratory failure, not elsewhere classified
0.000 0.418 0.582
K80 Cholelithiasis
0.000 0.423 0.577
K60.4 Rectal fistula
0.000 0.424 0.575
K52.0 Gastro-enteritis and colitis due to radiation
0.000 0.426 0.574
I11 Hypertensive heart disease
0.000 0.426 0.574
L10-L14 Bullous disorders
0.000 0.426 0.574
K55.9 Vascular disorder of intestine, unspecified
0.000 0.428 0.572
E83.3 Disorders of phosphorus metabolism
0.551 0.428 0.021
K74.0 Hepatic fibrosis
0.000 0.428 0.571
M60-M63 Disorders of muscles
0.000 0.429 0.571
K91.1 Postgastric surgery syndromes
0.000 0.431 0.569
K63.0 Abscess of intestine
0.000 0.431 0.568
E84 Cystic fibrosis
0.001 0.433 0.566
E07.8 Other specified disorders of thyroid
0.000 0.434 0.566
E83.9 Disorder of mineral metabolism, unspecified
0.531 0.434 0.035
K91.0 Vomiting following gastro-intestinal surgery
0.000 0.434 0.565
M70 Soft tissue disorders related to use, overuse and pressure
0.000 0.435 0.565
J98.9 Respiratory disorder, unspecified
0.000 0.435 0.565
K81.8 Other cholecystitis
0.000 0.435 0.564
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.000 0.435 0.564
M14.4 Arthropathy in amyloidosis
0.000 0.435 0.564
M14.3 Lipoid dermatoarthritis
0.000 0.435 0.564
M14.2 Diabetic arthropathy
0.000 0.435 0.564
M14.1 Crystal arthropathy in other metabolic disorders
0.000 0.435 0.564
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.000 0.435 0.564

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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