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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1014552
log Bayes Factor = 15.2389
Chromosome 4   position 25,108,270  (GRCh37) Explore rs1014552 on Ensembl!
Variant rs1014552 is part of Cluster X0274

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
0.999 0.001 0.000
N30-N39 Other diseases of urinary system
0.999 0.001 0.000
N32 Other disorders of bladder
0.998 0.002 0.000
N32.8 Other specified disorders of bladder
0.997 0.003 0.000
Chapter I Certain infectious and parasitic diseases
0.997 0.003 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.995 0.005 0.000
Chapter XX External causes of morbidity and mortality
0.992 0.008 0.000
T43.2 Other and unspecified antidepressants
0.987 0.013 0.000
S00-S09 Injuries to the head
0.980 0.020 0.000
H30-H36 Disorders of choroid and retina
0.980 0.020 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.976 0.024 0.000
Chapter X Diseases of the respiratory system
0.965 0.035 0.000
B95-B98 Bacterial, viral and other infectious agents
0.965 0.035 0.000
J40-J47 Chronic lower respiratory diseases
0.957 0.043 0.000
H35 Other retinal disorders
0.953 0.047 0.000
H25-H28 Disorders of lens
0.952 0.048 0.000
S09 Other and unspecified injuries of head
0.952 0.048 0.000
Chapter VIII Diseases of the ear and mastoid process
0.942 0.058 0.000
J44 Other chronic obstructive pulmonary disease
0.941 0.059 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.936 0.064 0.000
S50-S59 Injuries to the elbow and forearm
0.935 0.065 0.000
O60-O75 Complications of labour and delivery
0.934 0.066 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.934 0.066 0.000
Chapter XXII Codes for special purposes
0.932 0.068 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.932 0.068 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.929 0.071 0.000
H25 Senile cataract
0.928 0.072 0.000
S80-S89 Injuries to the knee and lower leg
0.927 0.073 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.927 0.073 0.000
S09.9 Unspecified injury of head
0.922 0.078 0.000
J30-J39 Other diseases of upper respiratory tract
0.918 0.082 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.912 0.088 0.000
H35.3 Degeneration of macula and posterior pole
0.910 0.090 0.000
H25.9 Senile cataract, unspecified
0.905 0.095 0.000
N32.9 Bladder disorder, unspecified
0.901 0.099 0.000
N00-N08 Glomerular diseases
0.900 0.100 0.000
H65-H75 Diseases of middle ear and mastoid
0.900 0.100 0.000
A00-A09 Intestinal infectious diseases
0.893 0.107 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.891 0.109 0.000
N60-N64 Disorders of breast
0.886 0.114 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.882 0.118 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.881 0.119 0.000
O00-O08 Pregnancy with abortive outcome
0.879 0.121 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.877 0.123 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.872 0.128 0.000
Chapter VI Diseases of the nervous system
0.872 0.128 0.000
O72 Postpartum haemorrhage
0.872 0.128 0.000
N17-N19 Renal failure
0.871 0.129 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.869 0.131 0.000
Chapter V Mental and behavioural disorders
0.869 0.131 0.000
H33 Retinal detachments and breaks
0.864 0.136 0.000
S82 Fracture of lower leg, including ankle
0.864 0.136 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.861 0.139 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.856 0.144 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.852 0.148 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.851 0.149 0.000
S52 Fracture of forearm
0.847 0.153 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.846 0.154 0.000
Y83.8 Other surgical procedures
0.845 0.155 0.000
Chapter II Neoplasms
0.842 0.158 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.842 0.158 0.000
T66-T78 Other and unspecified effects of external causes
0.842 0.158 0.000
H53-H54 Visual disturbances and blindness
0.839 0.161 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.839 0.161 0.000
J43 Emphysema
0.838 0.162 0.000
W20-W49 Exposure to inanimate mechanical forces
0.835 0.165 0.000
J46 Status asthmaticus
0.835 0.165 0.000
J32 Chronic sinusitis
0.833 0.167 0.000
U80 Agent resistant to penicillin and related antibiotics
0.831 0.168 0.000
X60-X84 Intentional self-harm
0.824 0.176 0.000
N60 Benign mammary dysplasia
0.823 0.177 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.822 0.178 0.000
H35.7 Separation of retinal layers
0.821 0.179 0.000
A30-A49 Other bacterial diseases
0.821 0.179 0.000
N73 Other female pelvic inflammatory diseases
0.820 0.180 0.000
S06 Intracranial injury
0.820 0.180 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.819 0.181 0.000
O72.1 Other immediate postpartum haemorrhage
0.817 0.183 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.816 0.184 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.812 0.188 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.810 0.190 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.804 0.196 0.000
J60-J70 Lung diseases due to external agents
0.800 0.200 0.000
T40.2 Other opioids
0.798 0.202 0.000
C64-C68 Malignant neoplasms of urinary tract
0.797 0.203 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.797 0.203 0.000
N72 Inflammatory disease of cervix uteri
0.797 0.203 0.000
S52.0 Fracture of upper end of ulna
0.796 0.204 0.000
T92 Sequelae of injuries of upper limb
0.796 0.204 0.000
N10-N16 Renal tubulo-interstitial diseases
0.790 0.210 0.000
G40-G47 Episodic and paroxysmal disorders
0.790 0.210 0.000
T42.4 Benzodiazepines
0.789 0.211 0.000
T39.0 Salicylates
0.787 0.213 0.000
H43-H45 Disorders of vitreous body and globe
0.787 0.213 0.000
B35-B49 Mycoses
0.785 0.215 0.000
J32.9 Chronic sinusitis, unspecified
0.784 0.216 0.000
H65 Nonsuppurative otitis media
0.780 0.220 0.000
H50 Other strabismus
0.780 0.220 0.000
N35 Urethral stricture
0.780 0.220 0.000
H66 Suppurative and unspecified otitis media
0.780 0.220 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.779 0.221 0.000
J40 Bronchitis, not specified as acute or chronic
0.778 0.222 0.000
S10-S19 Injuries to the neck
0.777 0.223 0.000
A80-A89 Viral infections of the central nervous system
0.776 0.224 0.000
J37 Chronic laryngitis and laryngotracheitis
0.775 0.225 0.000
S60-S69 Injuries to the wrist and hand
0.775 0.225 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.774 0.226 0.000
H25.1 Senile nuclear cataract
0.773 0.227 0.000
N18 Chronic renal failure
0.772 0.228 0.000
N32.3 Diverticulum of bladder
0.770 0.230 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.770 0.230 0.000
W00-W19 Falls
0.770 0.230 0.000
N03 Chronic nephritic syndrome
0.768 0.232 0.000
S00 Superficial injury of head
0.767 0.233 0.000
S09.8 Other specified injuries of head
0.767 0.233 0.000
J30 Vasomotor and allergic rhinitis
0.767 0.233 0.000
T90 Sequelae of injuries of head
0.766 0.234 0.000
A04 Other bacterial intestinal infections
0.765 0.235 0.000
C67 Malignant neoplasm of bladder
0.765 0.235 0.000
V40-V49 Car occupant injured in transport accident
0.763 0.237 0.000
V10-V19 Pedal cyclist injured in transport accident
0.762 0.238 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.762 0.238 0.000
N60.1 Diffuse cystic mastopathy
0.762 0.238 0.000
H53 Visual disturbances
0.762 0.238 0.000
H52 Disorders of refraction and accommodation
0.761 0.239 0.000
H10-H13 Disorders of conjunctiva
0.760 0.239 0.000
S52.00 Fracture of upper end of ulna (closed)
0.760 0.240 0.000
S82.3 Fracture of lower end of tibia
0.760 0.240 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.760 0.240 0.000
H33.0 Retinal detachment with retinal break
0.759 0.241 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.759 0.241 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.757 0.242 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.757 0.243 0.000
T93 Sequelae of injuries of lower limb
0.755 0.245 0.000
Y86 Sequelae of other accidents
0.755 0.245 0.000
U80.1 Methicillin resistant agent
0.754 0.246 0.000
J43.9 Emphysema, unspecified
0.753 0.247 0.000
S40-S49 Injuries to the shoulder and upper arm
0.752 0.248 0.000
N04 Nephrotic syndrome
0.751 0.249 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.751 0.249 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.751 0.249 0.000
S51 Open wound of forearm
0.751 0.249 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.748 0.252 0.000
N63 Unspecified lump in breast
0.747 0.253 0.000
H60-H62 Diseases of external ear
0.746 0.253 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.747 0.253 0.000
A08 Viral and other specified intestinal infections
0.744 0.256 0.000
F60-F69 Disorders of adult personality and behaviour
0.743 0.257 0.000
B25-B34 Other viral diseases
0.743 0.257 0.000
S02 Fracture of skull and facial bones
0.741 0.258 0.000
S50 Superficial injury of forearm
0.737 0.263 0.000
N73.6 Female pelvic peritoneal adhesions
0.736 0.264 0.000
J38.3 Other diseases of vocal cords
0.734 0.266 0.000
O04 Medical abortion
0.734 0.266 0.000
J38.0 Paralysis of vocal cords and larynx
0.733 0.267 0.000
T79-T79 Certain early complications of trauma
0.733 0.267 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.732 0.268 0.000
H34 Retinal vascular occlusions
0.732 0.268 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.732 0.268 0.000
H74 Other disorders of middle ear and mastoid
0.731 0.269 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.731 0.269 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.730 0.270 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.730 0.270 0.000
T51 Toxic effect of alcohol
0.729 0.271 0.000
O66 Other obstructed labour
0.729 0.271 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.729 0.271 0.000
S89 Other and unspecified injuries of lower leg
0.726 0.274 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.726 0.274 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.725 0.275 0.000
U80.8 Agent resistant to other penicillin-related antibiotic
0.725 0.275 0.000
Chapter IX Diseases of the circulatory system
0.724 0.276 0.000
N32.1 Vesicointestinal fistula
0.724 0.276 0.000
Y83.4 Other reconstructive surgery
0.723 0.277 0.000
N40-N51 Diseases of male genital organs
0.722 0.278 0.000
S70-S79 Injuries to the hip and thigh
0.722 0.278 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.722 0.278 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.722 0.278 0.000
H33.5 Other retinal detachments
0.720 0.280 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.718 0.282 0.000
O61 Failed induction of labour
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.717 0.283 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.717 0.283 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.717 0.283 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.717 0.283 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.717 0.283 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.717 0.283 0.000
T36 Poisoning by systemic antibiotics
0.717 0.283 0.000
N25-N29 Other disorders of kidney and ureter
0.717 0.283 0.000
N37 Urethral disorders in diseases classified elsewhere
0.716 0.284 0.000
N34 Urethritis and urethral syndrome
0.716 0.284 0.000
N33 Bladder disorders in diseases classified elsewhere
0.716 0.284 0.000
N32.4 Rupture of bladder, nontraumatic
0.716 0.284 0.000
N32.2 Vesical fistula, not elsewhere classified
0.716 0.284 0.000
B99-B99 Other infectious diseases
0.715 0.285 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.715 0.285 0.000
B65-B83 Helminthiases
0.715 0.285 0.000
B50-B64 Protozoal diseases
0.715 0.285 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.715 0.285 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.715 0.285 0.000
A75-A79 Rickettsioses
0.715 0.285 0.000
A70-A74 Other diseases caused by chlamydiae
0.715 0.285 0.000
A65-A69 Other spirochaetal diseases
0.715 0.285 0.000
A20-A28 Certain zoonotic bacterial diseases
0.715 0.285 0.000
A15-A19 Tuberculosis
0.715 0.285 0.000
D10-D36 Benign neoplasms
0.714 0.286 0.000
T43.9 Psychotropic drug, unspecified
0.713 0.287 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.713 0.287 0.000
T43.6 Psychostimulants with abuse potential
0.713 0.287 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.713 0.287 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.713 0.287 0.000
Y83.3 Surgical operation with formation of external stoma
0.712 0.288 0.000
H35.0 Background retinopathy and retinal vascular changes
0.712 0.288 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.711 0.289 0.000
Y35-Y36 Legal intervention and operations of war
0.711 0.289 0.000
Y10-Y34 Event of undetermined intent
0.711 0.289 0.000
Y00-Y09 Assault
0.711 0.289 0.000
X85-X99 Assault
0.711 0.289 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.711 0.289 0.000
X50-X57 Overexertion, travel and privation
0.711 0.289 0.000
X30-X39 Exposure to forces of nature
0.711 0.289 0.000
X20-X29 Contact with venomous animals and plants
0.711 0.289 0.000
X10-X19 Contact with heat and hot substances
0.711 0.289 0.000
X00-X09 Exposure to smoke, fire and flames
0.711 0.289 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.711 0.289 0.000
W75-W84 Other accidental threats to breathing
0.711 0.289 0.000
W65-W74 Accidental drowning and submersion
0.711 0.289 0.000
W50-W64 Exposure to animate mechanical forces
0.711 0.289 0.000
V98-V99 Other and unspecified transport accidents
0.711 0.289 0.000
V95-V97 Air and space transport accidents
0.711 0.289 0.000
V90-V94 Water transport accidents
0.711 0.289 0.000
V80-V89 Other land transport accidents
0.711 0.289 0.000
V70-V79 Bus occupant injured in transport accident
0.711 0.289 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.711 0.289 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.711 0.289 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.711 0.289 0.000
V01-V09 Pedestrian injured in transport accident
0.711 0.289 0.000
N70 Salpingitis and oophoritis
0.711 0.289 0.000
O70 Perineal laceration during delivery
0.710 0.290 0.000
V20-V29 Motorcycle rider injured in transport accident
0.708 0.292 0.000
N39 Other disorders of urinary system
0.706 0.294 0.000
T91 Sequelae of injuries of neck and trunk
0.705 0.295 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.704 0.296 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.704 0.296 0.000
S08 Traumatic amputation of part of head
0.703 0.297 0.000
S07 Crushing injury of head
0.703 0.297 0.000
S05 Injury of eye and orbit
0.703 0.297 0.000
S04 Injury of cranial nerves
0.703 0.297 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.703 0.297 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.703 0.297 0.000
H31 Other disorders of choroid
0.703 0.297 0.000
H30 Chorioretinal inflammation
0.703 0.297 0.000
H55-H59 Other disorders of eye and adnexa
0.702 0.298 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.702 0.298 0.000
D25 Leiomyoma of uterus
0.702 0.298 0.000
H49 Paralytic strabismus
0.701 0.299 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.700 0.299 0.000
O85-O92 Complications predominantly related to the puerperium
0.700 0.300 0.000
N99-N99 Other disorders of the genitourinary system
0.700 0.300 0.000
O02 Other abnormal products of conception
0.698 0.302 0.000
T92.1 Sequelae of fracture of arm
0.698 0.302 0.000
D25.9 Leiomyoma of uterus, unspecified
0.697 0.303 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.696 0.303 0.000
S20-S29 Injuries to the thorax
0.696 0.304 0.000
H65.9 Nonsuppurative otitis media, unspecified
0.696 0.304 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.696 0.304 0.000
S82.4 Fracture of fibula alone
0.695 0.305 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.694 0.306 0.000
T68 Hypothermia
0.694 0.306 0.000
B15-B19 Viral hepatitis
0.694 0.306 0.000
U51 Admission status on psychiatric patients
0.692 0.308 0.000
J69 Pneumonitis due to solids and liquids
0.692 0.308 0.000
B07 Viral warts
0.691 0.309 0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.690 0.310 0.000
H35.8 Other specified retinal disorders
0.690 0.310 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.690 0.310 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.689 0.311 0.000
S52.7 Multiple fractures of forearm
0.689 0.311 0.000
I60-I69 Cerebrovascular diseases
0.688 0.312 0.000
C51-C58 Malignant neoplasms of female genital organs
0.686 0.314 0.000
N36 Other disorders of urethra
0.686 0.314 0.000
J41 Simple and mucopurulent chronic bronchitis
0.686 0.314 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.685 0.315 0.000
N48 Other disorders of penis
0.685 0.315 0.000
S82.30 Fracture of lower end of tibia (closed)
0.685 0.315 0.000
N05 Unspecified nephritic syndrome
0.685 0.315 0.000
N75 Diseases of Bartholin's gland
0.685 0.315 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.685 0.315 0.000
Y84.8 Other medical procedures
0.684 0.316 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.684 0.316 0.000
H25.0 Senile incipient cataract
0.684 0.316 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.684 0.316 0.000
H35.9 Retinal disorder, unspecified
0.683 0.317 0.000
H35.6 Retinal haemorrhage
0.683 0.317 0.000
H35.5 Hereditary retinal dystrophy
0.683 0.317 0.000
H35.2 Other proliferative retinopathy
0.683 0.317 0.000
H35.1 Retinopathy of prematurity
0.683 0.317 0.000
T86 Failure and rejection of transplanted organs and tissues
0.683 0.317 0.000
T39.1 4-Aminophenol derivatives
0.683 0.317 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.683 0.317 0.000
H27 Other disorders of lens
0.683 0.317 0.000
O62 Abnormalities of forces of labour
0.683 0.317 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.682 0.317 0.000
S09.7 Multiple injuries of head
0.682 0.318 0.000
S09.2 Traumatic rupture of ear drum
0.682 0.318 0.000
S09.1 Injury of muscle and tendon of head
0.682 0.318 0.000
S09.0 Injury of blood vessels of head, not elsewhere classified
0.682 0.318 0.000
H72 Perforation of tympanic membrane
0.682 0.318 0.000
T40.4 Other synthetic narcotics
0.681 0.319 0.000
S06.5 Traumatic subdural haemorrhage
0.680 0.320 0.000
H50.9 Strabismus, unspecified
0.680 0.320 0.000
N76 Other inflammation of vagina and vulva
0.680 0.320 0.000
O03 Spontaneous abortion
0.679 0.321 0.000
H71 Cholesteatoma of middle ear
0.678 0.322 0.000
G20-G26 Extrapyramidal and movement disorders
0.678 0.322 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.677 0.323 0.000
N17 Acute renal failure
0.677 0.323 0.000
S90-S99 Injuries to the ankle and foot
0.676 0.323 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.676 0.324 0.000
C67.9 Bladder, unspecified
0.675 0.325 0.000
J37.0 Chronic laryngitis
0.673 0.327 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.673 0.327 0.000
N03.9 Unspecified
0.673 0.327 0.000
O00 Ectopic pregnancy
0.672 0.328 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.672 0.328 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.671 0.329 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.671 0.329 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.671 0.329 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.671 0.329 0.000
S59 Other and unspecified injuries of forearm
0.671 0.329 0.000
S58 Traumatic amputation of forearm
0.671 0.329 0.000
S57 Crushing injury of forearm
0.671 0.329 0.000
S56 Injury of muscle and tendon at forearm level
0.671 0.329 0.000
S55 Injury of blood vessels at forearm level
0.671 0.329 0.000
S54 Injury of nerves at forearm level
0.671 0.329 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.671 0.329 0.000
H90-H95 Other disorders of ear
0.670 0.330 0.000
S52.8 Fracture of other parts of forearm
0.670 0.330 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.670 0.330 0.000
O72.2 Delayed and secondary postpartum haemorrhage
0.670 0.330 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.670 0.330 0.000
O74 Complications of anaesthesia during labour and delivery
0.670 0.330 0.000
O73 Retained placenta and membranes, without haemorrhage
0.670 0.330 0.000
O71 Other obstetric trauma
0.670 0.330 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.670 0.330 0.000
O60 Preterm delivery
0.670 0.330 0.000
N74 Female pelvic inflammatory disorders in diseases classified elsewhere
0.670 0.330 0.000
N71 Inflammatory disease of uterus, except cervix
0.670 0.330 0.000
H35.4 Peripheral retinal degeneration
0.670 0.330 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.668 0.332 0.000
T98 Sequelae of other and unspecified effects of external causes
0.668 0.332 0.000
T95 Sequelae of burns, corrosions and frostbite
0.668 0.332 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.668 0.332 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.668 0.332 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.668 0.332 0.000
W29 Contact with other powered hand tools and household machinery
0.668 0.332 0.000
A41 Other septicaemia
0.668 0.332 0.000
N30 Cystitis
0.667 0.333 0.000
S62 Fracture at wrist and hand level
0.667 0.333 0.000
G43 Migraine
0.666 0.334 0.000
S82.1 Fracture of upper end of tibia
0.666 0.334 0.000
H66.9 Otitis media, unspecified
0.666 0.334 0.000
N64 Other disorders of breast
0.666 0.334 0.000
H25.2 Senile cataract, morgagnian type
0.666 0.334 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.665 0.334 0.000
S88 Traumatic amputation of lower leg
0.665 0.335 0.000
S87 Crushing injury of lower leg
0.665 0.335 0.000
S86 Injury of muscle and tendon at lower leg level
0.665 0.335 0.000
S85 Injury of blood vessels at lower leg level
0.665 0.335 0.000
S84 Injury of nerves at lower leg level
0.665 0.335 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.665 0.335 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.665 0.335 0.000
T39.4 Antirheumatics, not elsewhere classified
0.665 0.335 0.000
T39.2 Pyrazolone derivatives
0.665 0.335 0.000
H53.0 Amblyopia ex anopsia
0.664 0.336 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.663 0.337 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.662 0.338 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.661 0.339 0.000
F30-F39 Mood [affective] disorders
0.660 0.340 0.000
H33.2 Serous retinal detachment
0.660 0.340 0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere
0.659 0.341 0.000
T78 Adverse effects, not elsewhere classified
0.659 0.341 0.000
F80-F89 Disorders of psychological development
0.659 0.341 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.658 0.342 0.000
N60.2 Fibroadenosis of breast
0.657 0.342 0.000
N13 Obstructive and reflux uropathy
0.657 0.343 0.000
N39.4 Other specified urinary incontinence
0.656 0.344 0.000
H44 Disorders of globe
0.656 0.344 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.655 0.345 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.654 0.346 0.000
G82 Paraplegia and tetraplegia
0.654 0.346 0.000
H51 Other disorders of binocular movement
0.654 0.346 0.000
F60 Specific personality disorders
0.653 0.347 0.000
S82.0 Fracture of patella
0.652 0.348 0.000
S00.0 Superficial injury of scalp
0.652 0.348 0.000
T47.1 Other antacids and anti-gastric-secretion drugs
0.652 0.348 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.651 0.349 0.000
C67.2 Lateral wall of bladder
0.650 0.350 0.000
J36 Peritonsillar abscess
0.649 0.351 0.000
W22 Striking against or struck by other objects
0.648 0.351 0.000
H53.8 Other visual disturbances
0.648 0.352 0.000
J95-J99 Other diseases of the respiratory system
0.648 0.352 0.000
T90.2 Sequelae of fracture of skull and facial bones
0.647 0.353 0.000
G81 Hemiplegia
0.647 0.353 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.646 0.354 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.646 0.354 0.000
N06 Isolated proteinuria with specified morphological lesion
0.646 0.354 0.000
N01 Rapidly progressive nephritic syndrome
0.646 0.354 0.000
N00 Acute nephritic syndrome
0.646 0.354 0.000
J30.3 Other allergic rhinitis
0.646 0.354 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.645 0.355 0.000
H70 Mastoiditis and related conditions
0.645 0.355 0.000
H69 Other disorders of Eustachian tube
0.645 0.355 0.000
H68 Eustachian salpingitis and obstruction
0.645 0.355 0.000
H67 Otitis media in diseases classified elsewhere
0.645 0.355 0.000
N04.9 Unspecified
0.644 0.356 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.644 0.356 0.000
S82.6 Fracture of lateral malleolus
0.644 0.356 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.643 0.357 0.000
J38.2 Nodules of vocal cords
0.643 0.357 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.641 0.359 0.000
J39 Other diseases of upper respiratory tract
0.641 0.359 0.000
A07 Other protozoal intestinal diseases
0.640 0.360 0.000
A06 Amoebiasis
0.640 0.360 0.000
A05 Other bacterial foodborne intoxications
0.640 0.360 0.000
A03 Shigellosis
0.640 0.360 0.000
A02 Other Salmonella infections
0.640 0.360 0.000
A01 Typhoid and paratyphoid fevers
0.640 0.360 0.000
A00 Cholera
0.640 0.360 0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.639 0.361 0.000
T40.8 Lysergide [LSD]
0.639 0.361 0.000
T40.7 Cannabis (derivatives)
0.639 0.361 0.000
T40.6 Other and unspecified narcotics
0.639 0.361 0.000
T40.5 Cocaine
0.639 0.361 0.000
T40.3 Methadone
0.639 0.361 0.000
T40.1 Heroin
0.639 0.361 0.000
T40.0 Opium
0.639 0.361 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.638 0.362 0.000
E70-E90 Metabolic disorders
0.637 0.363 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.637 0.363 0.000
H52.1 Myopia
0.637 0.363 0.000
C67.3 Anterior wall of bladder
0.636 0.364 0.000
W25 Contact with sharp glass
0.635 0.365 0.000
S81 Open wound of lower leg
0.635 0.365 0.000
N18.9 Chronic renal failure, unspecified
0.634 0.366 0.000
S82.5 Fracture of medial malleolus
0.634 0.366 0.000
B37 Candidiasis
0.633 0.367 0.000
T87 Complications peculiar to reattachment and amputation
0.633 0.367 0.000
U81 Agent resistant to vancomycin and related antibiotics
0.631 0.369 0.000
U50 Level of care administered to neonates
0.631 0.369 0.000
U07 Emergency use of U07
0.631 0.369 0.000
U06 Emergency use of U06
0.631 0.369 0.000
U04 Severe acute respiratory syndrome [SARS]
0.631 0.369 0.000
U52 First in a series of a regular day/night admissions
0.631 0.369 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.630 0.370 0.000
O08 Complications following abortion and ectopic and molar pregnancy
0.630 0.370 0.000
O07 Failed attempted abortion
0.630 0.370 0.000
O06 Unspecified abortion
0.630 0.370 0.000
O05 Other abortion
0.630 0.370 0.000
O01 Hydatidiform mole
0.630 0.370 0.000
O04.9 Complete or unspecified, without complication
0.630 0.370 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.629 0.370 0.000
T81 Complications of procedures, not elsewhere classified
0.629 0.371 0.000
A49 Bacterial infection of unspecified site
0.628 0.372 0.000
T51.0 Ethanol
0.628 0.372 0.000
S82.8 Fractures of other parts of lower leg
0.627 0.373 0.000
G70-G73 Diseases of myoneural junction and muscle
0.625 0.375 0.000
O72.3 Postpartum coagulation defects
0.625 0.375 0.000
O72.0 Third-stage haemorrhage
0.625 0.375 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.625 0.375 0.000
H65.4 Other chronic nonsuppurative otitis media
0.625 0.375 0.000
N18.4 Chronic kidney disease, stage 4
0.625 0.375 0.000
S83.2 Tear of meniscus, current
0.624 0.376 0.000
H73 Other disorders of tympanic membrane
0.624 0.376 0.000
I63 Cerebral infarction
0.624 0.376 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.624 0.376 0.000
T93.2 Sequelae of other fractures of lower limb
0.623 0.377 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.623 0.377 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.623 0.377 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.623 0.377 0.000
T42.3 Barbiturates
0.623 0.377 0.000
T42.2 Succinimides and oxazolidinediones
0.623 0.377 0.000
T42.1 Iminostilbenes
0.623 0.377 0.000
T42.0 Hydantoin derivatives
0.623 0.377 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.623 0.377 0.000
F70-F79 Mental retardation
0.623 0.377 0.000
N35.9 Urethral stricture, unspecified
0.623 0.377 0.000
S67 Crushing injury of wrist and hand
0.623 0.377 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.623 0.377 0.000
S06.3 Focal brain injury
0.622 0.378 0.000
D27 Benign neoplasm of ovary
0.622 0.378 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.621 0.379 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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