TreeWAS – Variant ID: rs10245353

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I08 Multiple valve diseases	0.000	0.948	0.052
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.000	0.949	0.051
I08.1 Disorders of both mitral and tricuspid valves	0.000	0.949	0.051
I08.0 Disorders of both mitral and aortic valves	0.000	0.950	0.050
I08.2 Disorders of both aortic and tricuspid valves	0.000	0.955	0.045
I08.9 Multiple valve disease, unspecified	0.000	0.964	0.035
Z13.6 Special screening examination for cardiovascular disorders	0.000	0.969	0.031
I08.8 Other multiple valve diseases	0.000	0.972	0.028
S72.10 Pertrochanteric fracture (closed)	0.000	0.987	0.013
R22.4 Localised swelling, mass and lump, lower limb	0.008	0.992	0.000
I05-I09 Chronic rheumatic heart diseases	0.000	0.992	0.008
M93.9 Osteochondropathy, unspecified	0.008	0.992	0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.007	0.993	0.000
K72.9 Hepatic failure, unspecified	0.000	0.993	0.007
S72.1 Pertrochanteric fracture	0.000	0.993	0.006
I09 Other rheumatic heart diseases	0.000	0.994	0.006
M93 Other osteochondropathies	0.006	0.994	0.000
I06 Rheumatic aortic valve diseases	0.000	0.994	0.005
E34.9 Endocrine disorder, unspecified	0.005	0.995	0.000
S72.11 Pertrochanteric fracture (open)	0.000	0.995	0.005
Y83.3 Surgical operation with formation of external stoma	0.000	0.995	0.005
I09.9 Rheumatic heart disease, unspecified	0.000	0.995	0.004
I09.8 Other specified rheumatic heart diseases	0.000	0.995	0.004
I09.2 Chronic rheumatic pericarditis	0.000	0.995	0.004
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.000	0.995	0.004
I09.0 Rheumatic myocarditis	0.000	0.995	0.004
M92 Other juvenile osteochondrosis	0.005	0.995	0.000
M91-M94 Chondropathies	0.005	0.995	0.000
K70.3 Alcoholic cirrhosis of liver	0.000	0.995	0.005
M93.8 Other specified osteochondropathies	0.004	0.995	0.000
M93.2 Osteochondritis dissecans	0.004	0.995	0.000
M93.1 Kienbock's disease of adults	0.004	0.995	0.000
M93.0 Slipped upper femoral epiphysis (nontraumatic)	0.004	0.995	0.000
K72 Hepatic failure, not elsewhere classified	0.000	0.996	0.004
M92.7 Juvenile osteochondrosis of metatarsus	0.004	0.996	0.000
K70 Alcoholic liver disease	0.000	0.996	0.004
I07 Rheumatic tricuspid valve diseases	0.000	0.996	0.004
I05 Rheumatic mitral valve diseases	0.000	0.996	0.004
I06.9 Rheumatic aortic valve disease, unspecified	0.000	0.996	0.004
I06.8 Other rheumatic aortic valve diseases	0.000	0.996	0.004
I06.2 Rheumatic aortic stenosis with insufficiency	0.000	0.996	0.004
I06.1 Rheumatic aortic insufficiency	0.000	0.996	0.004
M92.6 Juvenile osteochondrosis of tarsus	0.004	0.996	0.000
E34 Other endocrine disorders	0.004	0.996	0.000
M94 Other disorders of cartilage	0.004	0.996	0.000
J42 Unspecified chronic bronchitis	0.004	0.996	0.000
M94.88 Other specified disorders of cartilage (Other)	0.004	0.996	0.000
M91 Juvenile osteochondrosis of hip and pelvis	0.004	0.996	0.000
K70.4 Alcoholic hepatic failure	0.000	0.996	0.004
M94.8 Other specified disorders of cartilage	0.004	0.996	0.000
K70.0 Alcoholic fatty liver	0.000	0.996	0.004
I06.0 Rheumatic aortic stenosis	0.000	0.996	0.003
K70.9 Alcoholic liver disease, unspecified	0.000	0.996	0.004
M92.5 Juvenile osteochondrosis of tibia and fibula	0.003	0.996	0.000
M92.1 Juvenile osteochondrosis of radius and ulna	0.003	0.996	0.000
M92.9 Juvenile osteochondrosis, unspecified	0.003	0.996	0.000
M92.8 Other specified juvenile osteochondrosis	0.003	0.996	0.000
M92.4 Juvenile osteochondrosis of patella	0.003	0.996	0.000
M92.3 Other juvenile osteochondrosis of upper limb	0.003	0.996	0.000
M92.2 Juvenile osteochondrosis of hand	0.003	0.996	0.000
M92.0 Juvenile osteochondrosis of humerus	0.003	0.996	0.000
H61.2 Impacted cerumen	0.004	0.996	0.000
I05.1 Rheumatic mitral insufficiency	0.000	0.996	0.003
M93.26 Osteochondritis dissecans knee	0.003	0.996	0.000
M93.86 Other specified osteochondropathies, lower leg	0.003	0.996	0.000
K72.1 Chronic hepatic failure	0.000	0.997	0.003
M94.0 Chondrocostal junction syndrome [Tietze]	0.003	0.997	0.000
E34.0 Carcinoid syndrome	0.003	0.997	0.000
I05.8 Other mitral valve diseases	0.000	0.997	0.003
K70.2 Alcoholic fibrosis and sclerosis of liver	0.000	0.997	0.003
I07.9 Tricuspid valve disease, unspecified	0.000	0.997	0.003
I07.8 Other tricuspid valve diseases	0.000	0.997	0.003
I07.2 Tricuspid stenosis with insufficiency	0.000	0.997	0.003
I07.0 Tricuspid stenosis	0.000	0.997	0.003
K70.1 Alcoholic hepatitis	0.000	0.997	0.003
H25.0 Senile incipient cataract	0.003	0.997	0.000
E34.5 Androgen resistance syndrome	0.003	0.997	0.000
E34.4 Constitutional tall stature	0.003	0.997	0.000
E34.3 Short stature, not elsewhere classified	0.003	0.997	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.003	0.997	0.000
E34.1 Other hypersecretion of intestinal hormones	0.003	0.997	0.000
M94.9 Disorder of cartilage, unspecified	0.003	0.997	0.000
E34.8 Other specified endocrine disorders	0.003	0.997	0.000
M94.3 Chondrolysis	0.003	0.997	0.000
M94.1 Relapsing polychondritis	0.003	0.997	0.000
M91.2 Coxa plana	0.003	0.997	0.000
K70-K77 Diseases of liver	0.000	0.997	0.003
I05.9 Mitral valve disease, unspecified	0.000	0.997	0.003
M91.1 Juvenile osteochondrosis of head of femur [Legg-Calve-Perthes]	0.003	0.997	0.000
E24 Cushing's syndrome	0.003	0.997	0.000
M94.87 Other specified disorders of cartilage (Ankle and foot)	0.003	0.997	0.000
M94.08 Chondrocostal junction syndrome [Tietze]-Other	0.003	0.997	0.000
M91.9 Juvenile osteochondrosis of hip and pelvis, unspecified	0.003	0.997	0.000
M91.8 Other juvenile osteochondrosis of hip and pelvis	0.003	0.997	0.000
M91.3 Pseudocoxalgia	0.003	0.997	0.000
M91.0 Juvenile osteochondrosis of pelvis	0.003	0.997	0.000
E20.9 Hypoparathyroidism, unspecified	0.003	0.997	0.000
E20-E35 Disorders of other endocrine glands	0.003	0.997	0.000
M94.85 Other specified disorders of cartilage (Pelvic region and thigh)	0.003	0.997	0.000
M94.84 Other specified disorders of cartilage (Hand)	0.003	0.997	0.000
M94.83 Other specified disorders of cartilage (Forearm)	0.003	0.997	0.000
M94.82 Other specified disorders of cartilage (Upper arm)	0.003	0.997	0.000
M94.81 Other specified disorders of cartilage (Shoulder region)	0.003	0.997	0.000
M94.80 Other specified disorders of cartilage (Multiple sites)	0.003	0.997	0.000
E20 Hypoparathyroidism	0.003	0.997	0.000
E28 Ovarian dysfunction	0.003	0.997	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.003	0.997	0.000
M92.10 Juvenile osteochondrosis of radius and ulna, unspecified arm	0.003	0.997	0.000
M92.51 Juvenile osteochondrosis of tibia and fibula, right leg	0.003	0.997	0.000
M92.50 Juvenile osteochondrosis of tibia and fibula, unspecified leg	0.003	0.997	0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.000	0.997	0.003
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)	0.003	0.997	0.000
K72.0 Acute and subacute hepatic failure	0.000	0.997	0.003
K74.0 Hepatic fibrosis	0.000	0.997	0.003
K75.0 Abscess of liver	0.000	0.997	0.003
E24.8 Other Cushing's syndrome	0.003	0.997	0.000
M94.09 Chondrocostal junction syndrome [Tietze]-Site unspec	0.003	0.997	0.000
M94.07 Chondrocostal junction syndrome [Tietze]-Ankle/foot	0.003	0.997	0.000
M94.06 Chondrocostal junction syndrome [Tietze]-Lower leg	0.003	0.997	0.000
M94.05 Chondrocostal junction syndrome [Tietze]-Pelvic/thigh	0.003	0.997	0.000
M94.04 Chondrocostal junction syndrome [Tietze]-Hand	0.003	0.997	0.000
M94.03 Chondrocostal junction syndrome [Tietze]-Forearm	0.003	0.997	0.000
M94.02 Chondrocostal junction syndrome [Tietze]-Upper arm	0.003	0.997	0.000
M94.01 Chondrocostal junction syndrome [Tietze]-Shldr region	0.003	0.997	0.000
M94.00 Chondrocostal junction syndrome [Tietze]-Mult sites	0.003	0.997	0.000
E28.3 Primary ovarian failure	0.003	0.997	0.000
H61.8 Other specified disorders of external ear	0.003	0.997	0.000
K75 Other inflammatory liver diseases	0.000	0.997	0.003
H61 Other disorders of external ear	0.003	0.997	0.000
E25 Adrenogenital disorders	0.003	0.997	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.003	0.997	0.000
E24.2 Drug-induced Cushing's syndrome	0.003	0.997	0.000
M91.20 Coxa plana-Mult sites	0.002	0.997	0.000
I05.2 Mitral stenosis with insufficiency	0.000	0.997	0.002
M94.2 Chondromalacia	0.002	0.997	0.000
L43.9 Lichen planus, unspecified	0.000	0.997	0.003
M94.86 Other specified disorders of cartilage (Lower leg)	0.003	0.997	0.000
M94.96 Disorder of cartilage, unspecified (Lower leg)	0.002	0.997	0.000
K75.9 Inflammatory liver disease, unspecified	0.000	0.997	0.003
E24.9 Cushing's syndrome, unspecified	0.003	0.997	0.000
M94.99 Disorder of cartilage, unspecified (Site unspecified)	0.002	0.997	0.000
M94.98 Disorder of cartilage, unspecified (Other)	0.002	0.997	0.000
M94.97 Disorder of cartilage, unspecified (Ankle and foot)	0.002	0.997	0.000
M94.95 Disorder of cartilage, unspecified (Pelvic region and thigh)	0.002	0.997	0.000
M94.94 Disorder of cartilage, unspecified (Hand)	0.002	0.997	0.000
M94.93 Disorder of cartilage, unspecified (Forearm)	0.002	0.997	0.000
M94.92 Disorder of cartilage, unspecified (Upper arm)	0.002	0.997	0.000
M94.91 Disorder of cartilage, unspecified (Shoulder region)	0.002	0.997	0.000
M94.90 Disorder of cartilage, unspecified (Multiple sites)	0.002	0.997	0.000
E24.0 Pituitary-dependent Cushing's disease	0.002	0.997	0.000
M94.19 Relapsing polychondritis (Site unspecified)	0.002	0.997	0.000
M94.18 Relapsing polychondritis (Other)	0.002	0.997	0.000
M94.17 Relapsing polychondritis (Ankle and foot)	0.002	0.997	0.000
M94.16 Relapsing polychondritis (Lower leg)	0.002	0.997	0.000
M94.15 Relapsing polychondritis (Pelvic region and thigh)	0.002	0.997	0.000
M94.14 Relapsing polychondritis (Hand)	0.002	0.997	0.000
M94.13 Relapsing polychondritis (Forearm)	0.002	0.997	0.000
M94.12 Relapsing polychondritis (Upper arm)	0.002	0.997	0.000
M94.11 Relapsing polychondritis (Shoulder region)	0.002	0.997	0.000
M94.10 Relapsing polychondritis (Multiple sites)	0.002	0.997	0.000
M94.39 Chondrolysis (Site unspecified)	0.002	0.997	0.000
M94.38 Chondrolysis (Other)	0.002	0.997	0.000
M94.37 Chondrolysis (Ankle and foot)	0.002	0.997	0.000
M94.36 Chondrolysis (Lower leg)	0.002	0.997	0.000
M94.35 Chondrolysis (Pelvic region and thigh)	0.002	0.997	0.000
M94.34 Chondrolysis (Hand)	0.002	0.997	0.000
M94.33 Chondrolysis (Forearm)	0.002	0.997	0.000
M94.32 Chondrolysis (Upper arm)	0.002	0.997	0.000
M94.31 Chondrolysis (Shoulder region)	0.002	0.997	0.000
M94.30 Chondrolysis (Multiple sites)	0.002	0.997	0.000
E28.2 Polycystic ovarian syndrome	0.003	0.997	0.000
M91.29 Coxa plana-Site unspec	0.002	0.997	0.000
M91.28 Coxa plana-Other	0.002	0.997	0.000
M91.27 Coxa plana-Ankle/Foot	0.002	0.997	0.000
M91.26 Coxa plana-Lower Leg	0.002	0.997	0.000
M91.25 Coxa plana-Pelvic/Thigh	0.002	0.997	0.000
M91.24 Coxa plana-Hand	0.002	0.997	0.000
M91.23 Coxa plana-Forearm	0.002	0.997	0.000
M91.22 Coxa plana-Upper arm	0.002	0.997	0.000
M91.21 Coxa plana-Shldr region	0.002	0.997	0.000
D47.1 Chronic myeloproliferative disease	0.000	0.997	0.003
M91.15 Juv osteochondrosis head of femur [Legg-Calve-Perthes]-Pelv	0.002	0.997	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.002	0.997	0.000
K77 Liver disorders in diseases classified elsewhere	0.000	0.997	0.002
S42.20 Fracture of upper end of humerus (closed)	0.003	0.997	0.000
K74 Fibrosis and cirrhosis of liver	0.000	0.997	0.003
M94.89 Other specified disorders of cartilage (Site unspecified)	0.002	0.997	0.000
Z03.8 Observation for other suspected diseases and conditions	0.000	0.997	0.003
M91.19 Juv osteochondrosis head of femur [Legg-Calve-Perthes]-Site	0.002	0.998	0.000
M91.18 Juv osteochondrosis head of femur [Legg-Calve-Perthes]-Othe	0.002	0.998	0.000
M91.17 Juv osteochondrosis head of femur [Legg-Calve-Perthes]-Ankl	0.002	0.998	0.000
M91.16 Juv osteochondrosis head of femur [Legg-Calve-Perthes]-Lowe	0.002	0.998	0.000
M91.14 Juv osteochondrosis head of femur [Legg-Calve-Perthes]-Hand	0.002	0.998	0.000
M91.13 Juv osteochondrosis head of femur [Legg-Calve-Perthes]-Fore	0.002	0.998	0.000
M91.12 Juv osteochondrosis head of femur [Legg-Calve-Perthes]-Uppe	0.002	0.998	0.000
M91.11 Juv osteochondrosis head of femur [Legg-Calve-Perthes]-Shld	0.002	0.998	0.000
M91.10 Juv osteochondrosis head of femur [Legg-Calve-Perthes]-Mult	0.002	0.998	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.002	0.998	0.000
E24.3 Ectopic ACTH syndrome	0.002	0.998	0.000
E24.1 Nelson's syndrome	0.002	0.998	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.002	0.998	0.000
I05.0 Mitral stenosis	0.000	0.998	0.002
M91.09 Juvenile osteochondrosis of pelvis-Site unspec	0.002	0.998	0.000
M91.08 Juvenile osteochondrosis of pelvis-Other	0.002	0.998	0.000
M91.07 Juvenile osteochondrosis of pelvis-Ankle/Foot	0.002	0.998	0.000
M91.06 Juvenile osteochondrosis of pelvis-Lower Leg	0.002	0.998	0.000
M91.05 Juvenile osteochondrosis of pelvis-Pelvic/Thigh	0.002	0.998	0.000
M91.04 Juvenile osteochondrosis of pelvis-Hand	0.002	0.998	0.000
M91.03 Juvenile osteochondrosis of pelvis-Forearm	0.002	0.998	0.000
M91.02 Juvenile osteochondrosis of pelvis-Upper arm	0.002	0.998	0.000
M91.01 Juvenile osteochondrosis of pelvis-Shldr region	0.002	0.998	0.000
M91.00 Juvenile osteochondrosis of pelvis-Mult sites	0.002	0.998	0.000
M91.39 Pseudocoxalgia-Site unspec	0.002	0.998	0.000
M91.38 Pseudocoxalgia-Other	0.002	0.998	0.000
M91.37 Pseudocoxalgia-Ankle/Foot	0.002	0.998	0.000
M91.36 Pseudocoxalgia-Lower Leg	0.002	0.998	0.000
M91.35 Pseudocoxalgia-Pelvic/Thigh	0.002	0.998	0.000
M91.34 Pseudocoxalgia-Hand	0.002	0.998	0.000
M91.33 Pseudocoxalgia-Forearm	0.002	0.998	0.000
M91.32 Pseudocoxalgia-Upper arm	0.002	0.998	0.000
M91.31 Pseudocoxalgia-Shldr region	0.002	0.998	0.000
M91.30 Pseudocoxalgia-Mult sites	0.002	0.998	0.000
M91.89 Other juvenile osteochondrosis of hip and pelvis-Site unspe	0.002	0.998	0.000
M91.88 Other juvenile osteochondrosis of hip and pelvis-Other	0.002	0.998	0.000
M91.87 Other juvenile osteochondrosis of hip and pelvis-Ankle/Foot	0.002	0.998	0.000
M91.86 Other juvenile osteochondrosis of hip and pelvis-Lower Leg	0.002	0.998	0.000
M91.85 Other juvenile osteochondrosis of hip and pelvis-Pelvic/Thi	0.002	0.998	0.000
M91.84 Other juvenile osteochondrosis of hip and pelvis-Hand	0.002	0.998	0.000
M91.83 Other juvenile osteochondrosis of hip and pelvis-Forearm	0.002	0.998	0.000
M91.82 Other juvenile osteochondrosis of hip and pelvis-Upper arm	0.002	0.998	0.000
M91.81 Other juvenile osteochondrosis of hip and pelvis-Shldr regi	0.002	0.998	0.000
M91.80 Other juvenile osteochondrosis of hip and pelvis (Multiple sites)	0.002	0.998	0.000
M91.99 Juvenile osteochondrosis of hip and pelvis, unspecified-Sit	0.002	0.998	0.000
M91.98 Juvenile osteochondrosis of hip and pelvis, unspecified-Oth	0.002	0.998	0.000
M91.97 Juvenile osteochondrosis of hip and pelvis, unspecified-Ank	0.002	0.998	0.000
M91.96 Juvenile osteochondrosis of hip and pelvis, unspecified-Low	0.002	0.998	0.000
M91.95 Juvenile osteochondrosis of hip and pelvis, unspecified-Pel	0.002	0.998	0.000
M91.94 Juvenile osteochondrosis of hip and pelvis, unspecified-Han	0.002	0.998	0.000
M91.93 Juvenile osteochondrosis of hip and pelvis, unspecified-For	0.002	0.998	0.000
M91.92 Juvenile osteochondrosis of hip and pelvis, unspecified-Upp	0.002	0.998	0.000
M91.91 Juvenile osteochondrosis of hip and pelvis, unspecified-Shl	0.002	0.998	0.000
M91.90 Juvenile osteochondrosis of hip and pelvis, unspecified (Multiple sites)	0.002	0.998	0.000
E21.0 Primary hyperparathyroidism	0.002	0.998	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.002	0.998	0.000
E32 Diseases of thymus	0.002	0.998	0.000
E31 Polyglandular dysfunction	0.002	0.998	0.000
E30 Disorders of puberty, not elsewhere classified	0.002	0.998	0.000
E20.8 Other hypoparathyroidism	0.002	0.998	0.000
E20.1 Pseudohypoparathyroidism	0.002	0.998	0.000
E20.0 Idiopathic hypoparathyroidism	0.002	0.998	0.000
E28.9 Ovarian dysfunction, unspecified	0.002	0.998	0.000
E28.8 Other ovarian dysfunction	0.002	0.998	0.000
E28.1 Androgen excess	0.002	0.998	0.000
E28.0 Oestrogen excess	0.002	0.998	0.000
G31.9 Degenerative disease of nervous system, unspecified	0.000	0.998	0.002
R27.0 Ataxia, unspecified	0.000	0.998	0.002
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.998	0.002
K71 Toxic liver disease	0.000	0.998	0.002
H61.3 Acquired stenosis of external ear canal	0.002	0.998	0.000
J92.9 Pleural plaque without asbestos	0.000	0.998	0.002
E27 Other disorders of adrenal gland	0.002	0.998	0.000
R60.0 Localised oedema	0.000	0.998	0.002
K38.1 Appendicular concretions	0.002	0.998	0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)	0.002	0.998	0.000
Z11.2 Special screening examination for other bacterial diseases	0.000	0.998	0.002
H61.9 Disorder of external ear, unspecified	0.002	0.998	0.000
Q28.2 Arteriovenous malformation of cerebral vessels	0.000	0.998	0.002
K75.3 Granulomatous hepatitis, not elsewhere classified	0.000	0.998	0.002
K75.2 Nonspecific reactive hepatitis	0.000	0.998	0.002
K75.1 Phlebitis of portal vein	0.000	0.998	0.002
E21.5 Disorder of parathyroid gland, unspecified	0.002	0.998	0.000
E21.4 Other specified disorders of parathyroid gland	0.002	0.998	0.000
E21.2 Other hyperparathyroidism	0.002	0.998	0.000
E25.9 Adrenogenital disorder, unspecified	0.002	0.998	0.000
E25.8 Other adrenogenital disorders	0.002	0.998	0.000
M94.29 Chondromalacia (Site unspecified)	0.002	0.998	0.000
M94.28 Chondromalacia (Other)	0.002	0.998	0.000
M94.27 Chondromalacia (Ankle and foot)	0.002	0.998	0.000
M94.25 Chondromalacia (Pelvic region and thigh)	0.002	0.998	0.000
M94.24 Chondromalacia (Hand)	0.002	0.998	0.000
M94.23 Chondromalacia (Forearm)	0.002	0.998	0.000
M94.22 Chondromalacia (Upper arm)	0.002	0.998	0.000
M94.21 Chondromalacia (Shoulder region)	0.002	0.998	0.000
M94.20 Chondromalacia (Multiple sites)	0.002	0.998	0.000
M23.2 Derangement of meniscus due to old tear or injury	0.002	0.998	0.000
K73 Chronic hepatitis, not elsewhere classified	0.000	0.998	0.002
N90.7 Vulvar cyst	0.000	0.998	0.002
E22 Hyperfunction of pituitary gland	0.002	0.998	0.000
H61.1 Non-infective disorders of pinna	0.002	0.998	0.000
K77.8 Liver disorders in other diseases classified elsewhere	0.000	0.998	0.002
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.000	0.998	0.002
K74.4 Secondary biliary cirrhosis	0.000	0.998	0.002
K74.2 Hepatic fibrosis with hepatic sclerosis	0.000	0.998	0.002
K74.1 Hepatic sclerosis	0.000	0.998	0.002
E26 Hyperaldosteronism	0.002	0.998	0.000
D03.3 Melanoma in situ of other and unspecified parts of face	0.000	0.998	0.002
H61.0 Perichondritis of external ear	0.002	0.998	0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)	0.002	0.998	0.000
E30.9 Disorder of puberty, unspecified	0.002	0.998	0.000
E30.8 Other disorders of puberty	0.002	0.998	0.000
E30.1 Precocious puberty	0.002	0.998	0.000
E30.0 Delayed puberty	0.002	0.998	0.000
E31.9 Polyglandular dysfunction, unspecified	0.002	0.998	0.000
E31.8 Other polyglandular dysfunction	0.002	0.998	0.000
E31.1 Polyglandular hyperfunction	0.002	0.998	0.000
E31.0 Autoimmune polyglandular failure	0.002	0.998	0.000
E32.9 Disease of thymus, unspecified	0.002	0.998	0.000
E32.8 Other diseases of thymus	0.002	0.998	0.000
E32.1 Abscess of thymus	0.002	0.998	0.000
E32.0 Persistent hyperplasia of thymus	0.002	0.998	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.002	0.998	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.002	0.998	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.002	0.998	0.000
K71.9 Toxic liver disease, unspecified	0.000	0.998	0.002
K71.8 Toxic liver disease with other disorders of liver	0.000	0.998	0.002
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.000	0.998	0.002
K71.6 Toxic liver disease with hepatitis, not elsewhere classified	0.000	0.998	0.002
K71.5 Toxic liver disease with chronic active hepatitis	0.000	0.998	0.002
K71.4 Toxic liver disease with chronic lobular hepatitis	0.000	0.998	0.002
K71.3 Toxic liver disease with chronic persistent hepatitis	0.000	0.998	0.002
K71.2 Toxic liver disease with acute hepatitis	0.000	0.998	0.002
K71.1 Toxic liver disease with hepatic necrosis	0.000	0.998	0.002
O14.0 Moderate preeclampsia	0.002	0.998	0.000
E29 Testicular dysfunction	0.002	0.998	0.000
E27.5 Adrenomedullary hyperfunction	0.002	0.998	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.002	0.998	0.000
E27.0 Other adrenocortical overactivity	0.002	0.998	0.000
I33.0 Acute and subacute infective endocarditis	0.000	0.998	0.002
K74.3 Primary biliary cirrhosis	0.000	0.998	0.002
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.002	0.998	0.000
K75.4 Autoimmune hepatitis	0.000	0.998	0.002
E27.2 Addisonian crisis	0.002	0.998	0.000
E27.1 Primary adrenocortical insufficiency	0.002	0.998	0.000
M23.27 Derangement of meniscus due to old tear or injury-Capsular	0.002	0.998	0.000
K73.8 Other chronic hepatitis, not elsewhere classified	0.000	0.998	0.002
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.000	0.998	0.002
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.000	0.998	0.002
K85.1 Biliary acute pancreatitis	0.000	0.998	0.002
Z98.1 Arthrodesis status	0.000	0.998	0.002
K71.0 Toxic liver disease with cholestasis	0.000	0.998	0.002
W49.6 Industrial and construction area	0.002	0.998	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.002	0.998	0.000
E22.8 Other hyperfunction of pituitary gland	0.002	0.998	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.002	0.998	0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.000	0.998	0.002
E22.0 Acromegaly and pituitary gigantism	0.002	0.998	0.000
K74.5 Biliary cirrhosis, unspecified	0.000	0.998	0.002
S72 Fracture of femur	0.000	0.998	0.002
D48.1 Connective and other soft tissue	0.002	0.998	0.000
E26.9 Hyperaldosteronism, unspecified	0.001	0.998	0.000
E26.8 Other hyperaldosteronism	0.001	0.998	0.000
E26.1 Secondary hyperaldosteronism	0.001	0.998	0.000
I72.4 Aneurysm of artery of lower extremity	0.000	0.998	0.002
D62 Acute posthaemorrhagic anaemia	0.000	0.998	0.002
K73.2 Chronic active hepatitis, not elsewhere classified	0.000	0.998	0.002
Z39.1 Care and examination of lactating mother	0.002	0.998	0.000
G31.8 Other specified degenerative diseases of nervous system	0.000	0.998	0.002
I45.9 Conduction disorder, unspecified	0.000	0.998	0.002
M94.26 Chondromalacia (Lower leg)	0.001	0.998	0.001
C43.5 Malignant melanoma of trunk	0.002	0.998	0.000
E29.9 Testicular dysfunction, unspecified	0.001	0.998	0.000
E29.8 Other testicular dysfunction	0.001	0.998	0.000
E29.0 Testicular hyperfunction	0.001	0.998	0.000
G31.0 Circumscribed brain atrophy	0.000	0.998	0.002
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.998	0.002
M77.91 Enthesopathy, unspecified (Shoulder region)	0.002	0.998	0.000
E27.8 Other specified disorders of adrenal gland	0.002	0.998	0.000
W24.9 Unspecified place	0.002	0.998	0.000
M21.24 Flexion deformity (Hand)	0.000	0.998	0.002
S72.8 Fractures of other parts of femur	0.000	0.998	0.002
I70.00 Atherosclerosis of aorta (without gangrene)	0.000	0.998	0.002
I30.9 Acute pericarditis, unspecified	0.002	0.998	0.000
R56.8 Other and unspecified convulsions	0.000	0.998	0.002
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.002	0.998	0.000
G31.1 Senile degeneration of brain, not elsewhere classified	0.000	0.998	0.001
N42.8 Other specified disorders of prostate	0.000	0.998	0.002
S72.80 Fractures of other parts of femur (closed)	0.000	0.998	0.001
I07.1 Tricuspid insufficiency	0.001	0.998	0.001
K73.9 Chronic hepatitis, unspecified	0.000	0.998	0.001
S22.00 Fracture of thoracic vertebra (closed)	0.000	0.998	0.002
E27.9 Disorder of adrenal gland, unspecified	0.001	0.998	0.000
G31.2 Degeneration of nervous system due to alcohol	0.000	0.998	0.001
S72.7 Multiple fractures of femur	0.000	0.998	0.001
Z92.6 Personal history of chemotherapy for neoplastic disease	0.000	0.998	0.002
G83.4 Cauda equina syndrome	0.000	0.998	0.002
D47.2 Monoclonal gammopathy	0.000	0.998	0.001
H72.0 Central perforation of tympanic membrane	0.002	0.998	0.000
C15.9 Oesophagus, unspecified	0.002	0.998	0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.000	0.998	0.002
Q28 Other congenital malformations of circulatory system	0.000	0.998	0.001
K82.1 Hydrops of gallbladder	0.001	0.999	0.000
S72.2 Subtrochanteric fracture	0.000	0.999	0.001
Z22.5 Carrier of viral hepatitis	0.000	0.999	0.001
S72.81 Fractures of other parts of femur (open)	0.000	0.999	0.001
A87.9 Viral meningitis, unspecified	0.000	0.999	0.001
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified	0.000	0.999	0.001
I51.8 Other ill-defined heart diseases	0.000	0.999	0.001
Q23.1 Congenital insufficiency of aortic valve	0.000	0.999	0.001
S72.9 Fracture of femur, part unspecified	0.000	0.999	0.001
S72.4 Fracture of lower end of femur	0.000	0.999	0.001
Z85.6 Personal history of leukaemia	0.001	0.999	0.000
I72 Other aneurysm	0.000	0.999	0.001
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.000	0.999	0.001
Q23.0 Congenital stenosis of aortic valve	0.000	0.999	0.001
E22.1 Hyperprolactinaemia	0.001	0.999	0.000
F41.2 Mixed anxiety and depressive disorder	0.001	0.999	0.000
M85.8 Other specified disorders of bone density and structure	0.001	0.999	0.000
W29.9 Unspecified place	0.001	0.999	0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.000	0.999	0.001
E26.0 Primary hyperaldosteronism	0.001	0.999	0.000
K35.9 Acute appendicitis, unspecified	0.000	0.999	0.001
O12.0 Gestational oedema	0.001	0.999	0.000
W24.6 Industrial and construction area	0.001	0.999	0.000
K37 Unspecified appendicitis	0.001	0.999	0.000
W24 Contact with lifting and transmission devices, not elsewhere classified	0.001	0.999	0.000
M85.87 Other specified disorders of bone density and structure (Ankle and foot)	0.001	0.999	0.000
I72.9 Aneurysm of unspecified site	0.000	0.999	0.001
K35.1 Acute appendicitis with peritoneal abscess	0.001	0.999	0.000
M25.74 Osteophyte (Hand)	0.001	0.999	0.000
S72.71 Multiple fractures of femur (open)	0.000	0.999	0.001
S72.70 Multiple fractures of femur (closed)	0.000	0.999	0.001
E29.1 Testicular hypofunction	0.000	0.999	0.001
F31.9 Bipolar affective disorder, unspecified	0.001	0.999	0.000
I70.0 Atherosclerosis of aorta	0.000	0.999	0.001
I72.0 Aneurysm of carotid artery	0.000	0.999	0.001
K21.0 Gastro-oesophageal reflux disease with oesophagitis	0.001	0.999	0.000
W49 Exposure to other and unspecified inanimate mechanical forces	0.001	0.999	0.000
M85.88 Other specified disorders of bone density and structure (Other)	0.001	0.999	0.000
I72.3 Aneurysm of iliac artery	0.000	0.999	0.001
F84.5 Asperger's syndrome	0.001	0.999	0.000
I72.2 Aneurysm of renal artery	0.000	0.999	0.001
O20.0 Threatened abortion	0.001	0.999	0.000
S68.1 Traumatic amputation of other single finger (complete)(partial)	0.001	0.999	0.000
S72.3 Fracture of shaft of femur	0.000	0.999	0.001
S72.21 Subtrochanteric fracture (open)	0.000	0.999	0.001
C45.7 Mesothelioma of other sites	0.000	0.999	0.001
Q28.9 Congenital malformation of circulatory system, unspecified	0.000	0.999	0.001
Q28.8 Other specified congenital malformations of circulatory system	0.000	0.999	0.001
Q28.3 Other malformations of cerebral vessels	0.000	0.999	0.001
Q28.1 Other malformations of precerebral vessels	0.000	0.999	0.001
Q28.0 Arteriovenous malformation of precerebral vessels	0.000	0.999	0.001
V19.8 Pedal cyclist [any] injured in other specified transport accidents	0.001	0.999	0.000
W49.0 Home	0.001	0.999	0.000
Z92.4 Personal history of major surgery, not elsewhere classified	0.000	0.999	0.001
M85.80 Other specified disorders of bone density and structure (Multiple sites)	0.001	0.999	0.000
S72.91 Fracture of femur, part unspecified (open)	0.000	0.999	0.001
D75.2 Essential thrombocytosis	0.001	0.999	0.000
E53.8 Deficiency of other specified B group vitamins	0.001	0.999	0.000
G58.8 Other specified mononeuropathies	0.001	0.999	0.000
I72.6 Aneurysm and dissection of vertebral artery	0.000	0.999	0.001
I72.5 Aneurysm and dissection of other precerebral arteries	0.000	0.999	0.001
I72.1 Aneurysm of artery of upper extremity	0.000	0.999	0.001
M50.1 Cervical disk disorder with radiculopathy	0.000	0.999	0.001
S42.2 Fracture of upper end of humerus	0.001	0.999	0.000
L43 Lichen planus	0.000	0.999	0.001
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.001	0.999	0.000
M85.86 Other specified disorders of bone density and structure (Lower leg)	0.001	0.999	0.000
M85.84 Other specified disorders of bone density and structure (Hand)	0.001	0.999	0.000
M85.83 Other specified disorders of bone density and structure (Forearm)	0.001	0.999	0.000
M85.82 Other specified disorders of bone density and structure (Upper arm)	0.001	0.999	0.000
M85.81 Other specified disorders of bone density and structure (Shoulder region)	0.001	0.999	0.000
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.000	0.999	0.001
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]	0.000	0.999	0.001
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour	0.000	0.999	0.001
H33.5 Other retinal detachments	0.001	0.999	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.000	0.999	0.001
I71 Aortic aneurysm and dissection	0.000	0.999	0.001
Q23 Congenital malformations of aortic and mitral valves	0.000	0.999	0.001
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)	0.001	0.999	0.000
W24.8 Other specified place	0.001	0.999	0.000
W24.7 Farm	0.001	0.999	0.000
W24.5 Trade and service area	0.001	0.999	0.000
W24.4 Street and highway	0.001	0.999	0.000
W24.3 Sports and athletics area	0.001	0.999	0.000
W24.2 School, other institution and public administrative area	0.001	0.999	0.000
W24.1 Residential institution	0.001	0.999	0.000
W24.0 Home	0.001	0.999	0.000
W25.8 Other specified place	0.001	0.999	0.000
W49.8 Other specified place	0.001	0.999	0.000
W49.7 Farm	0.001	0.999	0.000
W49.5 Trade and service area	0.001	0.999	0.000
W49.4 Street and highway	0.001	0.999	0.000
W49.3 Sports and athletics area	0.001	0.999	0.000
W49.2 School, other institution and public administrative area	0.001	0.999	0.000
W49.1 Residential institution	0.001	0.999	0.000
J92 Pleural plaque	0.000	0.999	0.001
K38 Other diseases of appendix	0.001	0.999	0.000
I70.01 Atherosclerosis of aorta (with gangrene)	0.000	0.999	0.001
S36.10 Injury of liver or gallbladder (without open wound into cavity)	0.000	0.999	0.001
S72.40 Fracture of lower end of femur (closed)	0.000	0.999	0.001
C45.0 Mesothelioma of pleura	0.000	0.999	0.001
I72.8 Aneurysm of other specified arteries	0.000	0.999	0.001
M77.96 Enthesopathy, unspecified (Lower leg)	0.001	0.999	0.000
S72.20 Subtrochanteric fracture (closed)	0.000	0.999	0.001
S72.31 Fracture of shaft of femur (open)	0.000	0.999	0.001
S72.41 Fracture of lower end of femur (open)	0.000	0.999	0.001
O12.2 Gestational oedema with proteinuria	0.001	0.999	0.000
X78.0 Home	0.001	0.999	0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.001	0.999	0.000
S72.90 Fracture of femur, part unspecified (closed)	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations