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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs10431397
log Bayes Factor = 0.624202
Chromosome 12   position 118,106,194  (GRCh37) Explore rs10431397 on Ensembl!
Variant rs10431397 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.247 0.753
I25 Chronic ischaemic heart disease
0.000 0.251 0.749
I20-I25 Ischaemic heart diseases
0.000 0.265 0.735
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.294 0.706
I21 Acute myocardial infarction
0.000 0.308 0.692
I21.9 Acute myocardial infarction, unspecified
0.000 0.324 0.676
Chapter IX Diseases of the circulatory system
0.000 0.338 0.662
I30-I52 Other forms of heart disease
0.000 0.342 0.658
I50 Heart failure
0.000 0.348 0.652
I50.0 Congestive heart failure
0.000 0.361 0.639
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.378 0.622
I51 Complications and ill-defined descriptions of heart disease
0.000 0.403 0.597
I73 Other peripheral vascular diseases
0.000 0.413 0.587
I24 Other acute ischaemic heart diseases
0.000 0.432 0.568
I25.2 Old myocardial infarction
0.000 0.438 0.562
I22 Subsequent myocardial infarction
0.000 0.441 0.559
I73.9 Peripheral vascular disease, unspecified
0.000 0.448 0.552
I47 Paroxysmal tachycardia
0.000 0.454 0.546
I50.1 Left ventricular failure
0.000 0.457 0.543
I51.7 Cardiomegaly
0.000 0.461 0.539
I25.6 Silent myocardial ischaemia
0.000 0.463 0.537
I25.4 Coronary artery aneurysm
0.000 0.463 0.537
I25.3 Aneurysm of heart
0.000 0.463 0.537
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.463 0.537
I31 Other diseases of pericardium
0.000 0.470 0.530
I23 Certain current complications following acute myocardial infarction
0.000 0.473 0.527
I25.5 Ischaemic cardiomyopathy
0.000 0.477 0.523
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.478 0.522
I50.9 Heart failure, unspecified
0.000 0.479 0.521
I20 Angina pectoris
0.000 0.479 0.521
I49 Other cardiac arrhythmias
0.000 0.480 0.520
I71 Aortic aneurysm and dissection
0.000 0.502 0.498
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.503 0.496
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.503 0.496
I42 Cardiomyopathy
0.000 0.504 0.496
I05-I09 Chronic rheumatic heart diseases
0.000 0.511 0.489
I46 Cardiac arrest
0.000 0.514 0.486
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.515 0.484
I47.2 Ventricular tachycardia
0.000 0.520 0.480
I21.4 Acute subendocardial myocardial infarction
0.000 0.520 0.480
I00-I02 Acute rheumatic fever
0.000 0.525 0.474
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.527 0.472
I52 Other heart disorders in diseases classified elsewhere
0.000 0.528 0.472
I48 Atrial fibrillation and flutter
0.000 0.528 0.472
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.528 0.472
I41 Myocarditis in diseases classified elsewhere
0.000 0.528 0.472
I40 Acute myocarditis
0.000 0.528 0.472
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.528 0.472
I37 Pulmonary valve disorders
0.000 0.528 0.472
I36 Nonrheumatic tricuspid valve disorders
0.000 0.528 0.472
I33 Acute and subacute endocarditis
0.000 0.528 0.472
I32 Pericarditis in diseases classified elsewhere
0.000 0.528 0.472
I30 Acute pericarditis
0.000 0.528 0.472
I77 Other disorders of arteries and arterioles
0.000 0.528 0.472
I51.9 Heart disease, unspecified
0.000 0.533 0.467
I73.0 Raynaud's syndrome
0.000 0.533 0.467
I35 Nonrheumatic aortic valve disorders
0.000 0.550 0.450
I25.1 Atherosclerotic heart disease
0.000 0.550 0.450
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.554 0.446
I72 Other aneurysm
0.000 0.554 0.446
I70 Atherosclerosis
0.000 0.554 0.446
I24.8 Other forms of acute ischaemic heart disease
0.000 0.561 0.439
I51.8 Other ill-defined heart diseases
0.000 0.563 0.437
I34 Nonrheumatic mitral valve disorders
0.000 0.565 0.434
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.568 0.432
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.571 0.429
I51.6 Cardiovascular disease, unspecified
0.000 0.571 0.428
I51.5 Myocardial degeneration
0.000 0.571 0.428
I51.4 Myocarditis, unspecified
0.000 0.571 0.428
I51.3 Intracardiac thrombosis, not elsewhere classified
0.000 0.571 0.428
I51.2 Rupture of papillary muscle, not elsewhere classified
0.000 0.571 0.428
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.000 0.571 0.428
I51.0 Cardiac septal defect, acquired
0.000 0.571 0.428
I20.9 Angina pectoris, unspecified
0.000 0.573 0.427
I49.3 Ventricular premature depolarisation
0.000 0.574 0.426
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.577 0.423
I74 Arterial embolism and thrombosis
0.000 0.578 0.422
I73.8 Other specified peripheral vascular diseases
0.000 0.579 0.421
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.579 0.421
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.582 0.418
I31.3 Pericardial effusion (noninflammatory)
0.000 0.585 0.415
I78 Diseases of capillaries
0.000 0.586 0.414
I31.9 Disease of pericardium, unspecified
0.000 0.588 0.412
I24.1 Dressler's syndrome
0.000 0.593 0.407
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.593 0.407
I42.0 Dilated cardiomyopathy
0.000 0.597 0.403
I22.8 Subsequent myocardial infarction of other sites
0.000 0.599 0.401
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.599 0.401
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.599 0.401
I20.8 Other forms of angina pectoris
0.000 0.601 0.399
I46.0 Cardiac arrest with successful resuscitation
0.000 0.603 0.397
I49.5 Sick sinus syndrome
0.000 0.608 0.392
I47.9 Paroxysmal tachycardia, unspecified
0.000 0.608 0.392
I47.0 Reentry ventricular arrhythmia
0.000 0.608 0.392
I49.9 Cardiac arrhythmia, unspecified
0.000 0.610 0.389
I27 Other pulmonary heart diseases
0.000 0.613 0.387
I77.1 Stricture of artery
0.000 0.615 0.385
I10-I15 Hypertensive diseases
0.000 0.619 0.381
I31.8 Other specified diseases of pericardium
0.000 0.620 0.380
I31.2 Haemopericardium, not elsewhere classified
0.000 0.620 0.380
I31.1 Chronic constrictive pericarditis
0.000 0.620 0.380
I31.0 Chronic adhesive pericarditis
0.000 0.620 0.380
I49.0 Ventricular fibrillation and flutter
0.000 0.620 0.380
I23.8 Other current complications following acute myocardial infarction
0.000 0.622 0.378
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.622 0.378
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.622 0.378
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.622 0.378
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.622 0.378
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.622 0.378
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.622 0.378
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.622 0.378
I49.2 Junctional premature depolarisation
0.000 0.627 0.373
I49.1 Atrial premature depolarisation
0.000 0.627 0.373
I45 Other conduction disorders
0.000 0.631 0.369
I08 Multiple valve diseases
0.000 0.635 0.365
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.635 0.365
I35.1 Aortic (valve) insufficiency
0.000 0.637 0.363
I47.1 Supraventricular tachycardia
0.000 0.641 0.359
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.643 0.357
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.643 0.357
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.643 0.357
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.643 0.357
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.643 0.357
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.643 0.357
I71.0 Dissection of aorta [any part]
0.000 0.643 0.357
I42.8 Other cardiomyopathies
0.000 0.644 0.356
I42.7 Cardiomyopathy due to drugs and other external agents
0.000 0.644 0.356
I42.6 Alcoholic cardiomyopathy
0.000 0.644 0.356
I42.5 Other restrictive cardiomyopathy
0.000 0.644 0.356
I42.4 Endocardial fibroelastosis
0.000 0.644 0.356
I42.3 Endomyocardial (eosinophilic) disease
0.000 0.644 0.356
I42.2 Other hypertrophic cardiomyopathy
0.000 0.644 0.356
I42.1 Obstructive hypertrophic cardiomyopathy
0.000 0.644 0.356
I09 Other rheumatic heart diseases
0.000 0.649 0.351
I07 Rheumatic tricuspid valve diseases
0.000 0.649 0.351
I06 Rheumatic aortic valve diseases
0.000 0.649 0.351
I05 Rheumatic mitral valve diseases
0.000 0.649 0.351
I49.4 Other and unspecified premature depolarisation
0.000 0.649 0.350
I34.0 Mitral (valve) insufficiency
0.000 0.651 0.349
I46.1 Sudden cardiac death, so described
0.000 0.652 0.348
I28 Other diseases of pulmonary vessels
0.000 0.652 0.347
I20.1 Angina pectoris with documented spasm
0.000 0.654 0.346
I02 Rheumatic chorea
0.000 0.660 0.340
I01 Rheumatic fever with heart involvement
0.000 0.660 0.340
I00 Rheumatic fever without mention of heart involvement
0.000 0.660 0.340
I35.2 Aortic (valve) stenosis with insufficiency
0.000 0.661 0.339
I30.9 Acute pericarditis, unspecified
0.000 0.662 0.338
I30.8 Other forms of acute pericarditis
0.000 0.662 0.338
I30.1 Infective pericarditis
0.000 0.662 0.338
I30.0 Acute nonspecific idiopathic pericarditis
0.000 0.662 0.338
I32.8 Pericarditis in other diseases classified elsewhere
0.000 0.662 0.338
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.662 0.338
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.000 0.662 0.338
I33.9 Acute endocarditis, unspecified
0.000 0.662 0.338
I33.0 Acute and subacute infective endocarditis
0.000 0.662 0.338
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.000 0.662 0.338
I36.8 Other nonrheumatic tricuspid valve disorders
0.000 0.662 0.338
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.000 0.662 0.338
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.000 0.662 0.338
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.000 0.662 0.338
I37.9 Pulmonary valve disorder, unspecified
0.000 0.662 0.338
I37.8 Other pulmonary valve disorders
0.000 0.662 0.338
I37.2 Pulmonary valve stenosis with insufficiency
0.000 0.662 0.338
I37.1 Pulmonary valve insufficiency
0.000 0.662 0.338
I37.0 Pulmonary valve stenosis
0.000 0.662 0.338
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.000 0.662 0.338
I39.4 Multiple valve disorders in diseases classified elsewhere
0.000 0.662 0.338
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.000 0.662 0.338
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.000 0.662 0.338
I39.1 Aortic valve disorders in diseases classified elsewhere
0.000 0.662 0.338
I39.0 Mitral valve disorders in diseases classified elsewhere
0.000 0.662 0.338
I40.9 Acute myocarditis, unspecified
0.000 0.662 0.338
I40.8 Other acute myocarditis
0.000 0.662 0.338
I40.1 Isolated myocarditis
0.000 0.662 0.338
I40.0 Infective myocarditis
0.000 0.662 0.338
I41.8 Myocarditis in other diseases classified elsewhere
0.000 0.662 0.338
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.662 0.338
I41.1 Myocarditis in viral diseases classified elsewhere
0.000 0.662 0.338
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.000 0.662 0.338
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.000 0.662 0.338
I43.2 Cardiomyopathy in nutritional diseases
0.000 0.662 0.338
I43.1 Cardiomyopathy in metabolic diseases
0.000 0.662 0.338
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.000 0.662 0.338
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.000 0.662 0.338
I48.4 Atypical atrial flutter
0.000 0.662 0.338
I48.3 Typical atrial flutter
0.000 0.662 0.338
I48.2 Chronic atrial fibrillation
0.000 0.662 0.338
I48.1 Persistent atrial fibrillation
0.000 0.662 0.338
I48.0 Paroxysmal atrial fibrillation
0.000 0.662 0.338
I52.8 Other heart disorders in other diseases classified elsewhere
0.000 0.662 0.338
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.662 0.338
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.000 0.662 0.338
I77.8 Other specified disorders of arteries and arterioles
0.000 0.662 0.338
I77.5 Necrosis of artery
0.000 0.662 0.338
I77.4 Coeliac artery compression syndrome
0.000 0.662 0.338
I77.3 Arterial fibromuscular dysplasia
0.000 0.662 0.338
I77.2 Rupture of artery
0.000 0.662 0.338
I77.0 Arteriovenous fistula, acquired
0.000 0.662 0.338
I49.8 Other specified cardiac arrhythmias
0.000 0.663 0.337
I77.6 Arteritis, unspecified
0.000 0.664 0.336
I38 Endocarditis, valve unspecified
0.000 0.665 0.335
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.668 0.332
I35.9 Aortic valve disorder, unspecified
0.000 0.677 0.322
I35.8 Other aortic valve disorders
0.000 0.677 0.322
I42.9 Cardiomyopathy, unspecified
0.000 0.679 0.321
I70.9 Generalised and unspecified atherosclerosis
0.000 0.680 0.320
I70.8 Atherosclerosis of other arteries
0.000 0.680 0.320
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.680 0.320
I70.1 Atherosclerosis of renal artery
0.000 0.680 0.320
I70.0 Atherosclerosis of aorta
0.000 0.680 0.320
I72.9 Aneurysm of unspecified site
0.000 0.680 0.320
I72.8 Aneurysm of other specified arteries
0.000 0.680 0.320
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.680 0.320
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.680 0.320
I72.4 Aneurysm of artery of lower extremity
0.000 0.680 0.320
I72.3 Aneurysm of iliac artery
0.000 0.680 0.320
I72.2 Aneurysm of renal artery
0.000 0.680 0.320
I72.1 Aneurysm of artery of upper extremity
0.000 0.680 0.320
I72.0 Aneurysm of carotid artery
0.000 0.680 0.320
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.680 0.320
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.680 0.320
I79.1 Aortitis in diseases classified elsewhere
0.000 0.680 0.320
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.680 0.320
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.685 0.315
I27.0 Primary pulmonary hypertension
0.000 0.687 0.312
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.000 0.688 0.312
I34.8 Other nonrheumatic mitral valve disorders
0.000 0.688 0.312
I34.2 Nonrheumatic mitral (valve) stenosis
0.000 0.688 0.312
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.692 0.308
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.692 0.307
I99 Other and unspecified disorders of circulatory system
0.000 0.692 0.307
I26 Pulmonary embolism
0.000 0.694 0.306
I44 Atrioventricular and left bundle-branch block
0.000 0.697 0.303
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.697 0.303
I74.8 Embolism and thrombosis of other arteries
0.000 0.697 0.303
I74.5 Embolism and thrombosis of iliac artery
0.000 0.697 0.303
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.697 0.303
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.697 0.303
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.697 0.303
I78.9 Disease of capillaries, unspecified
0.000 0.703 0.297
I78.8 Other diseases of capillaries
0.000 0.703 0.297
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.703 0.297
I46.9 Cardiac arrest, unspecified
0.000 0.706 0.294
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.707 0.293
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.000 0.712 0.288
I27.2 Other secondary pulmonary hypertension
0.000 0.715 0.284
I08.1 Disorders of both mitral and tricuspid valves
0.000 0.716 0.284
I95 Hypotension
0.000 0.720 0.280
I27.9 Pulmonary heart disease, unspecified
0.000 0.722 0.278
I27.8 Other specified pulmonary heart diseases
0.000 0.722 0.278
I27.1 Kyphoscoliotic heart disease
0.000 0.722 0.278
I20.0 Unstable angina
0.000 0.724 0.276
I15 Secondary hypertension
0.000 0.727 0.273
I13 Hypertensive heart and renal disease
0.000 0.727 0.273
I11 Hypertensive heart disease
0.000 0.727 0.273
I12 Hypertensive renal disease
0.000 0.734 0.266
I45.9 Conduction disorder, unspecified
0.000 0.735 0.265
I45.8 Other specified conduction disorders
0.000 0.735 0.265
I45.6 Preexcitation syndrome
0.000 0.735 0.265
I45.5 Other specified heart block
0.000 0.735 0.265
I45.4 Nonspecific intraventricular block
0.000 0.735 0.265
I45.3 Trifascicular block
0.000 0.735 0.265
I45.2 Bifascicular block
0.000 0.735 0.265
I45.0 Right fascicular block
0.000 0.735 0.265
I78.1 Naevus, nonneoplastic
0.000 0.735 0.264
I08.9 Multiple valve disease, unspecified
0.000 0.738 0.262
I08.8 Other multiple valve diseases
0.000 0.738 0.262
I08.2 Disorders of both aortic and tricuspid valves
0.000 0.738 0.262
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.738 0.262
I05.9 Mitral valve disease, unspecified
0.000 0.748 0.251
I05.8 Other mitral valve diseases
0.000 0.748 0.251
I05.2 Mitral stenosis with insufficiency
0.000 0.748 0.251
I05.1 Rheumatic mitral insufficiency
0.000 0.748 0.251
I05.0 Mitral stenosis
0.000 0.748 0.251
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.748 0.251
I06.8 Other rheumatic aortic valve diseases
0.000 0.748 0.251
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.748 0.251
I06.1 Rheumatic aortic insufficiency
0.000 0.748 0.251
I06.0 Rheumatic aortic stenosis
0.000 0.748 0.251
I07.9 Tricuspid valve disease, unspecified
0.000 0.748 0.251
I07.8 Other tricuspid valve diseases
0.000 0.748 0.251
I07.2 Tricuspid stenosis with insufficiency
0.000 0.748 0.251
I07.1 Tricuspid insufficiency
0.000 0.748 0.251
I07.0 Tricuspid stenosis
0.000 0.748 0.251
I09.9 Rheumatic heart disease, unspecified
0.000 0.748 0.251
I09.8 Other specified rheumatic heart diseases
0.000 0.748 0.251
I09.2 Chronic rheumatic pericarditis
0.000 0.748 0.251
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.748 0.251
I09.0 Rheumatic myocarditis
0.000 0.748 0.251
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.751 0.249
I28.8 Other specified diseases of pulmonary vessels
0.000 0.751 0.249
I28.1 Aneurysm of pulmonary artery
0.000 0.751 0.249
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.751 0.249
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.756 0.244
I01.8 Other acute rheumatic heart disease
0.000 0.756 0.244
I01.2 Acute rheumatic myocarditis
0.000 0.756 0.244
I01.1 Acute rheumatic endocarditis
0.000 0.756 0.244
I01.0 Acute rheumatic pericarditis
0.000 0.756 0.244
I02.9 Rheumatic chorea without heart involvement
0.000 0.756 0.244
I02.0 Rheumatic chorea with heart involvement
0.000 0.756 0.244
I60-I69 Cerebrovascular diseases
0.000 0.757 0.242
I95.9 Hypotension, unspecified
0.000 0.763 0.237
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.770 0.229
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.770 0.229
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.770 0.229
I70.10 Atherosclerosis of renal artery (without gangrene)
0.000 0.770 0.229
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.770 0.229
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.770 0.229
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.770 0.229
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.770 0.229
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.770 0.229
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.770 0.229
I44.2 Atrioventricular block, complete
0.000 0.774 0.226
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.779 0.221
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.779 0.221
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.779 0.221
I97.1 Other functional disturbances following cardiac surgery
0.000 0.779 0.221
I97.0 Postcardiotomy syndrome
0.000 0.779 0.221
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.000 0.780 0.219
I44.6 Other and unspecified fascicular block
0.000 0.783 0.217
I44.5 Left posterior fascicular block
0.000 0.783 0.217
I44.4 Left anterior fascicular block
0.000 0.783 0.217
I44.3 Other and unspecified atrioventricular block
0.000 0.783 0.217
I08.0 Disorders of both mitral and aortic valves
0.000 0.785 0.214
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.790 0.210
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.790 0.210
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.790 0.210
I98.0 Cardiovascular syphilis
0.000 0.790 0.210
I12.0 Hypertensive renal disease with renal failure
0.000 0.795 0.205
I34.1 Mitral (valve) prolapse
0.001 0.795 0.204
I95.8 Other hypotension
0.000 0.799 0.201
I95.0 Idiopathic hypotension
0.000 0.799 0.201
I35.0 Aortic (valve) stenosis
0.000 0.800 0.200
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.804 0.196
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.804 0.196
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.804 0.196
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.804 0.196
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.804 0.196
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.804 0.196
I15.9 Seconday hypertension, unspecified
0.000 0.804 0.196
I15.8 Other secondary hypertension
0.000 0.804 0.196
I15.2 Hypertension secondary to endocrine disorders
0.000 0.804 0.196
I15.1 Hypertension secondary to other renal disorders
0.000 0.804 0.196
I15.0 Renovascular hypertension
0.000 0.804 0.196
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.804 0.195
I44.0 Atrioventricular block, first degree
0.000 0.807 0.193
I61 Intracerebral haemorrhage
0.000 0.809 0.191
I10 Essential (primary) hypertension
0.000 0.809 0.191
I44.7 Left bundle-branch block, unspecified
0.000 0.819 0.180
I60 Subarachnoid haemorrhage
0.000 0.822 0.178
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.000 0.822 0.178
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.826 0.174
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.000 0.826 0.174
I62 Other nontraumatic intracranial haemorrhage
0.000 0.826 0.174
I95.2 Hypotension due to drugs
0.000 0.833 0.166
I12.9 Hypertensive renal disease without renal failure
0.000 0.835 0.165
I45.1 Other and unspecified right bundle-branch block
0.001 0.838 0.162
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.000 0.842 0.158
I61.9 Intracerebral haemorrhage, unspecified
0.000 0.845 0.155
I64 Stroke, not specified as haemorrhage or infarction
0.000 0.849 0.151
I44.1 Atrioventricular block, second degree
0.001 0.850 0.149
I67 Other cerebrovascular diseases
0.000 0.856 0.144
I69 Sequelae of cerebrovascular disease
0.000 0.857 0.143
I95.1 Orthostatic hypotension
0.000 0.857 0.142
I61.8 Other intracerebral haemorrhage
0.000 0.863 0.137
I61.6 Intracerebral haemorrhage, multiple localised
0.000 0.863 0.137
I61.5 Intracerebral haemorrhage, intraventricular
0.000 0.863 0.137
I61.4 Intracerebral haemorrhage in cerebellum
0.000 0.863 0.137
I61.3 Intracerebral haemorrhage in brain stem
0.000 0.863 0.137
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.000 0.863 0.137
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.000 0.863 0.137
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.000 0.863 0.137
I60.9 Subarachnoid haemorrhage, unspecified
0.000 0.868 0.132
I60.8 Other subarachnoid haemorrhage
0.000 0.872 0.128
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.000 0.872 0.128
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.000 0.872 0.128
I60.5 Subarachnoid haemorrhage from vertebral artery
0.000 0.872 0.128
I60.4 Subarachnoid haemorrhage from basilar artery
0.000 0.872 0.128
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.000 0.872 0.128
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.000 0.872 0.128
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.000 0.872 0.128
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.000 0.872 0.128
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.000 0.875 0.125
I62.1 Nontraumatic extradural haemorrhage
0.000 0.875 0.125
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.000 0.875 0.125
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.000 0.875 0.125
I66.8 Occlusion and stenosis of other cerebral artery
0.000 0.875 0.125
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.000 0.875 0.125
I66.3 Occlusion and stenosis of cerebellar arteries
0.000 0.875 0.125
I66.2 Occlusion and stenosis of posterior cerebral artery
0.000 0.875 0.125
I66.1 Occlusion and stenosis of anterior cerebral artery
0.000 0.875 0.125
I66.0 Occlusion and stenosis of middle cerebral artery
0.000 0.875 0.125
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.000 0.875 0.125
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.000 0.875 0.125
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.000 0.875 0.125
I68.0 Cerebral amyloid angiopathy
0.000 0.875 0.125
I63 Cerebral infarction
0.000 0.881 0.118
I67.1 Cerebral aneurysm, nonruptured
0.000 0.883 0.117
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.000 0.887 0.113
I65.8 Occlusion and stenosis of other precerebral artery
0.000 0.887 0.113
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.000 0.887 0.113
I65.1 Occlusion and stenosis of basilar artery
0.000 0.887 0.113
I65.0 Occlusion and stenosis of vertebral artery
0.000 0.887 0.113
I67.7 Cerebral arteritis, not elsewhere classified
0.000 0.896 0.103
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.000 0.896 0.103
I67.5 Moyamoya disease
0.000 0.896 0.103
I67.4 Hypertensive encephalopathy
0.000 0.896 0.103
I67.3 Progressive vascular leukoencephalopathy
0.000 0.896 0.103
I67.0 Dissection of cerebral arteries, nonruptured
0.000 0.896 0.103
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.000 0.897 0.102
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.000 0.897 0.102
I69.1 Sequelae of intracerebral haemorrhage
0.000 0.897 0.102
I69.0 Sequelae of subarachnoid haemorrhage
0.000 0.897 0.102
I67.9 Cerebrovascular disease, unspecified
0.000 0.902 0.097
I65.2 Occlusion and stenosis of carotid artery
0.000 0.903 0.097
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.000 0.904 0.096
I67.2 Cerebral atherosclerosis
0.000 0.911 0.089
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.000 0.915 0.085
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.000 0.915 0.085
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.000 0.915 0.085
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.000 0.915 0.085
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.000 0.915 0.085
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.000 0.915 0.085
I69.3 Sequelae of cerebral infarction
0.001 0.919 0.081
I67.8 Other specified cerebrovascular diseases
0.000 0.923 0.076
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.000 0.925 0.075
I63.8 Other cerebral infarction
0.000 0.926 0.073
I63.9 Cerebral infarction, unspecified
0.000 0.932 0.068
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.000 0.933 0.067
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.951 0.049
I88 Nonspecific lymphadenitis
0.000 0.951 0.048
I81 Portal vein thrombosis
0.000 0.951 0.048
I85 Oesophageal varices
0.000 0.952 0.048
I82 Other venous embolism and thrombosis
0.000 0.954 0.046
I86 Varicose veins of other sites
0.000 0.956 0.043
I87 Other disorders of veins
0.000 0.960 0.039
I89.0 Lymphoedema, not elsewhere classified
0.000 0.964 0.036
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified
0.000 0.964 0.035
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.964 0.035
I89.1 Lymphangitis
0.000 0.964 0.035
I88.9 Nonspecific lymphadenitis, unspecified
0.000 0.965 0.035
I88.8 Other nonspecific lymphadenitis
0.000 0.965 0.035
I88.1 Chronic lymphadenitis, except mesenteric
0.000 0.965 0.035
I88.0 Nonspecific mesenteric lymphadenitis
0.000 0.965 0.035
I85.0 Oesophageal varices with bleeding
0.000 0.965 0.035
I85.9 Oesophageal varices without bleeding
0.000 0.965 0.034
I82.9 Embolism and thrombosis of unspecified vein
0.000 0.966 0.033
I82.3 Embolism and thrombosis of renal vein
0.000 0.966 0.033
I82.2 Embolism and thrombosis of vena cava
0.000 0.966 0.033
I82.1 Thrombophlebitis migrans
0.000 0.966 0.033
I82.0 Budd-Chiari syndrome
0.000 0.966 0.033
I80 Phlebitis and thrombophlebitis
0.000 0.967 0.033
I86.8 Varicose veins of other specified sites
0.000 0.968 0.031
I86.4 Gastric varices
0.000 0.968 0.031
I86.3 Vulval varices
0.000 0.968 0.031
I86.2 Pelvic varices
0.000 0.968 0.031
I86.0 Sublingual varices
0.000 0.968 0.031
I82.8 Embolism and thrombosis of other specified veins
0.000 0.969 0.031
I87.9 Disorder of vein, unspecified
0.000 0.971 0.028
I87.2 Venous insufficiency (chronic) (peripheral)
0.000 0.971 0.028
I87.0 Postphlebitic syndrome
0.000 0.971 0.028
I83 Varicose veins of lower extremities
0.000 0.973 0.026
I86.1 Scrotal varices
0.000 0.973 0.026
I87.1 Compression of vein
0.000 0.975 0.025
I87.8 Other specified disorders of veins
0.001 0.975 0.024
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.000 0.976 0.024
I80.8 Phlebitis and thrombophlebitis of other sites
0.000 0.976 0.024
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.000 0.976 0.024
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.000 0.976 0.024
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.000 0.978 0.022
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.000 0.981 0.019
I83.1 Varicose veins of lower extremities with inflammation
0.000 0.981 0.019
H02 Other disorders of eyelid
0.000 0.982 0.018
I83.0 Varicose veins of lower extremities with ulcer
0.000 0.983 0.017
H02.9 Disorder of eyelid, unspecified
0.000 0.984 0.016
H02.0 Entropion and trichiasis of eyelid
0.000 0.984 0.016
H02.4 Ptosis of eyelid
0.000 0.984 0.016
H02.1 Ectropion of eyelid
0.000 0.985 0.015
H02.3 Blepharochalasis
0.000 0.985 0.015
H02.8 Other specified disorders of eyelid
0.000 0.986 0.014
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.000 0.987 0.013
H02.7 Other degenerative disorders of eyelid and periocular area
0.000 0.987 0.013
H02.6 Xanthelasma of eyelid
0.000 0.987 0.013
H02.5 Other disorders affecting eyelid function
0.000 0.987 0.013
H02.2 Lagophthalmos
0.000 0.987 0.013
I84 Haemorrhoids
0.000 0.988 0.012
K29.6 Other gastritis
0.000 0.989 0.011
I84.2 Internal haemorrhoids without complication
0.000 0.990 0.010
I84.4 External haemorrhoids with other complications
0.000 0.991 0.009
I84.3 External thrombosed haemorrhoids
0.000 0.991 0.008
I84.0 Internal thrombosed haemorrhoids
0.000 0.991 0.008
I84.5 External haemorrhoids without complication
0.000 0.992 0.008
I84.6 Residual haemorrhoidal skin tags
0.000 0.993 0.007
I84.7 Unspecified thrombosed haemorrhoids
0.000 0.993 0.006
R00.2 Palpitations
0.006 0.994 0.000
Z95.0 Presence of cardiac pacemaker
0.000 0.994 0.006
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.000 0.994 0.006
R60.0 Localised oedema
0.005 0.995 0.000
I84.8 Unspecified haemorrhoids with other complications
0.000 0.995 0.005
H00 Hordeolum and chalazion
0.000 0.995 0.005

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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